CN109984785A - A kind of medical instrument - Google Patents

Abstract

The present invention relates to a kind of medical instruments, more particularly to a kind of internal stitching unstrument, the internal stitching unstrument is prepared by biocompatible material, the internal stitching unstrument at least one can inhale mention target suture tissue negative pressure suction mention component, the internal stitching unstrument can enter internal through natural cavity or/and opening, in mucomembranous surface or deep, organ surface or deep, other tissue surfaces or deep are sutured and be closed or the suture and closure of other positions and mode, and adjustable inserting needle depth, metering needle hole distance, it can be interrupted or continuously suture and be closed, in parallel or series or it can intersect or repeat or any combination of pitch of the laps and other or they.

Description

A kind of medical instrument

The interaction of related application is looked after.

Prolong the part that the application can be the Application Serial that 2 months (application number 201810152994.7) on the 21st 2018 submit It is continuous.

Technical field

The present invention relates to a kind of medical instrument, more particularly at least one a kind of negative pressure inhales and mentions the internal of component or unit Stitching unstrument.

Background technique

Through scope by natural cavity and opening, previous some abdominals or laparoscopic surgery or Minimally Invasive Surgery can avoid Caused damage.

According to scope, can be diagnosed, cut off, drained, but suturing is still problem: (soft) scope does not have laparoscope hand The stiffness of art operating parts, and the tissue to be sewn in vivo is soft and is not fixed, and is difficult accurate inserting needle, pulls out needle, knots, it is non- Top (or target suture tissue superficial part) negative pressure inhales the bottom (or target suture tissue deep) that mentions, and pincers are grabbed, hook is chosen, are bored and carried etc. And easily injury tissue even if pincers are grabbed or hook is chosen or bored and carried tissue, and more or less blocks inserting needle, even if inserting needle, It is difficult to pull out needle again or continuously pulls out needle or continuous acupuncture, even if pulling out needle, and is difficult securely to knot.

Degree of safety height, low manufacture cost, endoscopic surgery suture instruments easy to operate, still belong to rare at present.

Summary of the invention

For solve the problems, such as it is above-mentioned it is in the prior art at least one, the present invention provides a kind of internal stitching unstrument, and biofacies Hold and at least one negative pressure inhales the internal stitching unstrument for mentioning component or unit.

Prepare biocompatible internal stitching unstrument, the suction of at least one negative pressure mention component or unit (can be rope strip or/ With horn-like or/and discoid or/and triangular shape or/and square or/and ellipse or/and any combination), stitching unstrument is through machine Body natural cavity or/and opening enter in vivo, in mucomembranous surface or deep, organ surface or deep, other tissue surfaces or depth Portion is sutured and is closed, and negative pressure suction mentions component or unit connection negative pressure generator, can be inhaled and be mentioned target suture tissue；Negative pressure suction mentions Component or unit can be connect with stitching unstrument any part, can also be with it without any connection；Negative pressure suction, which mentions component or unit, to be connect Sensor can judge that suction proposes classification, the depth, area, volume of tissue etc. according to this；Stitching unstrument adjustable inserting needle depth, metering needle Hole distance, between pitch-row tissue can swell therewith, can be interrupted or continuously suture and be closed, can in parallel or series intersect or repeat or Pitch of the laps and any combination thereof can be knotted in vivo by suture knotting guide structure and/or direct and/or default knot, can also Internal part is directed to after knotting in vitro, it is also possible to pre-knotted suture, self-adhesion bad mold joint, self-styled suture etc.；Stitching unstrument can be rolled over Folded or/and torsion or/and overturning or/and bending and any combination thereof, can also be placed in capsule body enter in vivo, remote control intelligence behaviour Make；Stitching unstrument can have needle track (gap), line storehouse, push away bolt, pulling plug, ear bar, linear slit, control wire, external manipulation unit etc.；Stitching unstrument and The mobile connection moment of its needlework and/or soft slow and/or interruption and/or continue and dress is had an effect or/and pushed and pulled to any combination thereof It sets；Stitching unstrument knotter or/and ligaturing forceps or/and manipulator or/and metal clip or/and high molecular polymer are pressed from both sides or/and are glued Needlework are fixed or/and are closed to conjunction or/and heat seal or/and other physics or/and chemical or/and biological method；Suture body Outer operating unit can use the third finger for the hand for holding scope and little finger of toe combined operation.

Beneficial effects of the present invention include can through natural cavity or/and opening in vivo surface or deep be sutured (into Needle pulls out needle, knots), component can be mentioned with negative pressure suction or unit suction mentions target suture tissue and (avoids or reduces tissue damage, keeps away Exempt from or reduce to stop inserting needle), camera lens pollution when endoscope distal suction can be reduced, and can control depth of needle and pin hole distance, Especially only rely on soft endoscopic technic.

Detailed description of the invention:

Fig. 1 is structural schematic diagram.

Component represented by label or position in Fig. 1 are as follows: 1- line storehouse；2- suture needle；3- C-shaped needle track；The horn-like negative pressure of 4- is inhaled Mention pipe；5- cylinder stitching unstrument toggle；6- endoscope distal；7- control wire.

Specific embodiment:

Below with reference to specific example, the invention will be further described:

Embodiment 1

Using biocompatible medical stainless steel material or/and other medical metals or/and medical polymer, prepares and be suitble to scope remote The cylindrical stitching unstrument toggle and c-type stitching unstrument needle track at end, needle track veutro or avris have a wavy linear slit, wavy amplitude with Size is suitable for suture and goes out needle track but suture needle does not drop out, and suture needle can use conventional operation needle, can also special suture needle as needed, Inserting needle and back stitching can rely on control wire, control wire extend to it is external (in vitro can by the hand of gripping scope the third finger and Little finger of toe combined operation), or/and elastic construction (such as spring, elastic slice, indent) is relied on, or/and dependence is electronic, or/and relies on Latch or/and card slot.Stitching unstrument veutro center or/and avris or/and outer rim center or/and avris, bondage or other modes have 1 Root or 2 or several horn-like negative pressure straws, sucker body outer end closely connect negative pressure pump, internal section can parallel bondage in interior Mirror；Negative pressure suction, which mentions component, can connect sensor, can judge that suction proposes classification, the depth, area, volume of tissue etc. according to this；All components All necessary edge is round and smooth to prevent injury tissue.C-type stitching unstrument and horn-like suction pipe enter in vivo with scope when operation, reach target Suture site, horn-like suction pipe alignment target suture tissue, propose target by negative pressure suction and suture tissue, then manipulate in needle track Suture needle is sutured.After suture, extracting passes around urgent knot, avoids Slipped Clove Hitch, false knot.After knotting, pincers road trimming can be used.

Embodiment 2

Using biocompatible medical stainless steel material or/and other medical metals or/and medical polymer, prepares and be suitble to scope remote The cylindrical stitching unstrument toggle and stitching unstrument needle track at end, suture needle can use conventional operation needle, can also special suture needle as needed. Stitching unstrument veutro center or/and avris or/and outer rim center or/and avris, disjunctor are connected to 1 or 2 or several round negative pressure Small sucker, sucker connect tubule, and the latter can be clamped road and be extended in vitro.The external close connection Manual negative pressure instrument or electronic in end Negative pressure pump, or connect the included negative pressure generator of scope.Target suture tissue is mentioned into the suction of internal sucker, stitching unstrument discharges elastic force, Moment promote suture needle enter inserting needle duct, across tissue, go back into needle outlet road, needle extracts suture needle out, passes through preset line It ties (can be preset in suture knotting guide structure), tight knotting can be taken out, be directed to after can also knotting in vitro by the prior art Part in vivo, it is also possible to which manipulator or intelligent distant control knot.

Embodiment 3

The arc needle track (also can adjust, and prepare the suture needle of the corresponding adjustment) of corresponding conventional suture needle of performing the operation is arranged at stitching unstrument top, Needle track veutro or avris have wavy linear slit, and (wavy amplitude is suitable for suture export and needle track with size but suture needle is not fallen Out), the bipod of lower part, inserting needle side can be clinohedral class taper bound feet (so as to vertical inserting needle), and needle side can be big foot (to go out needle out When pick up needle).Needle track middle section nearby sets ampulla shape for needle track, and center can have several unidirectional ampulla shape point stamens convenient for suture needle entrance Needle track, big ampulla shape bottom connect the subsequent ampullula invagination of inserting needle part to be more conducive to pick up needle after needle.Inserting needle duct inserting needle It can rely on inserting needle part (pushing away bolt), pushing away bolt can be located in needle track, push suture needle to enter in-vivo tissue by inserting needle duct along needle track, wear It crosses tissue, go back into needle outlet road；Inserting needle end can preset knot.Pushing away bolt center has pin hole, and pushing away behind bolt has in ampullula shape It falling into, pushes away bolt and can control (or up and down) and split, respectively there is an ear bar in (or the left and right) up and down for pushing away bolt, and ear bar connects bracing wire, when tensing bracing wire, Inserting needle part clamps, and initial operation person will can push away bolt as far as possible and lean on toward needle point to be more conducive to inserting needle.Needle outlet says needle and can rely on There is pin hole in needle (pulling plug), pulling plug center, and pulling plug can control (or upper and lower) and split, and respectively there is an ear in (or left and right) up and down of pulling plug Bar, ear bar connect bracing wire, and can external manipulation unit, when tensing bracing wire, pulling plug is clamped, and also be can rely on the bolt that pushes away replied and is clamped needle Tip connects and pulls out suture needle, and needle end can preset knot out, and suture needle passes through preset knot with suture, takes out tight knot.In needle out Wired storehouse between end and the big ampulla shape of needle track, when picking up needle after needle track big ampulla shape bottom falls after rise and pushes away bolt, pulling plug continues past Needle end is returned out to pull out suture, and suture is placed in line storehouse.Line storehouse can also be open (also not having to line storehouse).Push away bolt and pulling plug Have an effect can also be according to other power-assisteds such as pulling force of pendulum model inserting needle part or biopsy forceps power moment for may be from elastic component.When operation It is mountable on scope, can also combine or split be mounted on special pusher or all be mounted on special pusher, It can also be placed in class capsule body by well-known technique and enter internal, remote control intelligent operation, if stitching unstrument is buckled into double pincers with soft scope The pincers road 1 of road scope is in question mark shape；Endoscopic forceps channel 2 has bracing wire control to push away bolt, separately there is the control pulling plug of bracing wire；Scope is through esophagus Into internal, suture site, slides stitching unstrument in vivo, and scope is made to be located at stitching unstrument needle track center of top, (can be in laundry hanging fork shape Rely on the bracing wire adjustment for pushing away bolt and pulling plug), can also c-type plane indulge diameter perpendicular to scope leading end portion and stitched with being monitored from stitching unstrument avris It closes, other angles are conducive to visual field eyesight and operation.It is open and enters in vivo through human body natural, big foot is first fallen, until target site Fall bound feet after the slight protuberance of tissue again, the bottom surface local slope of bound feet is just with tissue close to vertical, convenient for inserting needle.Stitching unstrument abdomen Side center or/and avris or/and outer rim center or/and avris, have 1 or 2 or several negative pressure straws, sucker body outer end is close Connect negative pressure pump, internal section can parallel bondage in scope.Before inserting needle, destination organization first is mentioned with negative pressure straw suction；External bracing wire, Promotion, which pushes away bolt, makes suture needle enter inserting needle end along needle track, breaks through tissue surface, continues to push pin；It is mobile when needle end appears suture needle out Near pulling plug to suture needle, suture needle is vised, is moved to and pushes away near bolt, is unclamped, suture needle is taken advantage of a situation into needle track；After suture needle enters needle track, Pulling plug is retracted again to needle end out, until out behind needle end, then suture clamping is pulled to line storehouse, ampulla shape point stamen makes suture can only be toward one Direction (front) is mobile；If continuous suture, and so on moves, tail end suture can gradually be pulled in the line storehouse of closely needle track, or In continuous suture, after next needle pulls out needle, torsion bound feet is first mentioned, suture is made to drop out needle track through linear slit, then mentions torsion big foot, makes suture Drop out line storehouse and needle track other parts.Can also be respectively coronal separated by seat piece bipod, it is separated when stitching unstrument is transferred, when lifting simultaneously Hold together, that is, clamps the end of a thread at both ends.The big foot at needle end out, cuts with line.Big foot lifts i.e. clamping suture needle tip, pulls out needle；Big foot is multiple Original is covered in mucous membrane, i.e., slightly opens big foot, and suture needle enters needle track by line storehouse.Between first needle and last needle each needle suture away from From, it can be estimated and be shifted by scope, it is also combinable to move the continuous suture of boots displacement.The foot for going out needle end of c-type or horse-hof shape, has line It cuts, when being pulled to suitable, big foot inside cord cuts short suture；The coronal line of the bipod of c-type or horse-hof shape can also be separated, transfer the time-division It opens, closes up when lifting, that is, clamp the end of a thread at both ends, clamped respectively by big foot and bound feet, rotate 180 °, knot in this way.Also it can be used Needlework are fixed or/and are closed to metal clip or/and high molecular polymer folder or/and other methods.Draw after can also knotting in vitro It leads internal.

Embodiment 4

The suture at inserting needle end makes suture form half set side of surgery one hand knotting through knotting guide structure (be similar to yin and carve intaglio plate), out Needle end passes through the knotting and partly covers side, and both ends are with the biopsy forceps or special pusher of biopsy forceps or repacking and using seat piece as branch Point tenses suture to knot, and equally, the suture at needle end makes suture form half set of surgery one hand knotting through knotting guide structure out Side, inserting needle end pass through the knotting and partly cover side, and the biopsy forceps or special pusher and with seat piece of biopsy forceps or repacking are used in both ends again For fulcrum, tense suture and knot again, during which, can also seat piece all 180 ° of 180 ° of rotation or partition part rotation in favor of urgent the Two knots (avoiding Slipped Clove Hitch, false knot etc.).Using seat piece as fulcrum, so that it may suture is tensed to knot, without dissociating, will not be individually straight It connects and involves tissue.Through dynamics measurement, in the case where soaking suture with physiological saline, the pulling force > 150N.

Embodiment 5

Special culture media is prepared, the cell of toxicity test is V79 cell, it is added into 6 orifice plates, is cultivated for 24 hours to logarithmic growth, The leaching liquor of this sample is prepared, extraction ratio is 0.1g/mL, and the dilution of MEM05 culture medium prepares 4 concentration groups of large span, if Positive control and negative control are set, 33.3/mL cell suspension is prepared, is added in 6 orifice plates with every hole 3mL cell suspension amount, is incubated for For 24 hours, it inhales and abandons culture medium, 2mL leaching liquor is added in every hole, and it is parallel to prepare 3 holes, it is incubated for 6d, 8d, which inhales, abandons culture medium, PBS washing, first Alcohol is fixed, 5% Giemsa dyeing, colony-forming efficiency >=control group 70%.

Embodiment 6

With 3 male and healthy albefaction rabbits of strain, 2.61 ± 0.73kg of weight wipes out two sides backbone hair for 24 hours before experiment, preparation is originally Sample polarity and nonpolar leaching liquor, are provided to inject, observe each injection point surrounding skin, remembered by standard by GB/T 16886.10 Subsystem judges Test sites and control position erythema and oedema score value, finally scores < 1.0 as the result is shown.

Embodiment 7

10 week old CBA/Ca female mices, 35 are randomly divided into 5 groups (every group 7): each 1 group of 2 kinds of leaching liquors, 2 kinds of positive controls Each 1 group, 1 group of blank group.25 μ L/d mouse ears back sides continue 3d, and in last 1 record weight, iv marker measures cell Proliferation.Laboratory sample SI<3.0 as the result is shown, positive control>=3.0.

Part that the present invention does not relate to includes the identical prior art, or be can be realized by using the prior art.

Claims (10)

1. a kind of internal stitching unstrument, which is characterized in that the internal stitching unstrument is prepared by biocompatible material, the internal seam The suction of at least one negative pressure of clutch mentions component, and the internal stitching unstrument enters in vivo through body natural cavity or/and opening, viscous Film surface or deep, organ surface or deep, other tissue surfaces or deep are sutured and are closed.

2. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument negative pressure suction, which mentions component, to inhale Mention target suture tissue.

3. internal stitching unstrument according to claim 1, which is characterized in that the negative pressure suction of the internal stitching unstrument mentions component company Connect negative pressure generator.

4. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument negative pressure suction mentions component can be with The connection of stitching unstrument any part, can also be with it without any connection.

5. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument negative pressure suction, which mentions component, to be connect Sensor.

6. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument needle track veutro or avris have Wavy linear slit, wavy amplitude goes out needle track suitable for suture with size but suture needle does not drop out, and the internal stitching unstrument is adjustable Depth of needle, metering needle hole distance, between pitch-row tissue can swell therewith, can be interrupted or continuously suture and be closed, can in parallel or string Connection intersects or repeats or pitch of the laps and any combination thereof, and the internal stitching unstrument can be by suture knotting guide structure and/or straight Connect and/or preset knot to knot in vivo, internal part is directed to after can also knotting in vitro, it is also possible to pre-knotted suture, from Bond suture, self-styled suture etc..

7. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument is foldable or/and reverses Or/and overturning or/and bending and any combination thereof, can also be placed in capsule body enter in vivo, remote control intelligent operation.

8. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument can have needle track (gap), line Storehouse pushes away bolt, pulling plug, ear bar, linear slit, control wire, external manipulation unit etc., the mobile connection of the internal stitching unstrument and its needlework Moment and/or soft slow and/or interruption and/or continue and any combination thereof have an effect or/and push-pull device at fixed.

9. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument knotter or/and beat Knot pincers or/and manipulator or/and metal clip or/and high molecular polymer folder or/and bonding or/and heat seal or/and other physics Or/and needlework are fixed or/and be closed to chemical or/and biological method.

10. internal stitching unstrument according to claim 1, which is characterized in that the internal stitching unstrument in vitro operation unit can With the third finger for the hand for holding scope and little finger of toe combined operation.