CN109954088A - A kind of Chinese medicine of blood pressure lowering and preparation method thereof - Google Patents

A kind of Chinese medicine of blood pressure lowering and preparation method thereof Download PDF

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Publication number
CN109954088A
CN109954088A CN201711419967.3A CN201711419967A CN109954088A CN 109954088 A CN109954088 A CN 109954088A CN 201711419967 A CN201711419967 A CN 201711419967A CN 109954088 A CN109954088 A CN 109954088A
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parts
chinese medicine
motherwort
oyster
safflower
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CN201711419967.3A
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刘芬
张鹏
刘伟
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533—Leonurus (motherwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8988—Gastrodia

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Botany (AREA)
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  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to Chinese medicine of a kind of blood pressure lowering and preparation method thereof, which is made of the raw material of following weight proportion: 120 parts of uncaria, 120 parts of Poria cocos, 120 parts of Rhizoma Gastrodiae, 90 parts of Radix Salviae Miltiorrhizae, 90 parts of motherwort, 90 parts of Radix Angelicae Sinensis, 60 parts of semen plantaginis, 60 parts of safflower, 60 parts of oyster, 60 parts of dried orange peel, 60 parts of Herba Epimedii.Chinese medicine of the present invention has calming the liver to stop the wind, the function of blood circulation and channel invigorating.

Description

A kind of Chinese medicine of blood pressure lowering and preparation method thereof
Technical field
The present invention relates to Chinese medicines of a kind of blood pressure lowering and preparation method thereof, belong to the field of Chinese medicines.
Background technique
High blood pressure is since nervous centralis and humoral system dysfunction cause arterial pressure to increase for Major Clinical table Existing whole body chronic disease is a kind of common clinical, frequently-occurring disease, is the important risk factor for causing cardiovascular and cerebrovascular disease, together Complication caused by the organ functionals such as Shi Qixin, brain, kidney or organic change also seriously threatens the life and health of people.
Hypertension is common clinical, frequently-occurring disease, is one of cardiovascular disease common in the world today, disease incidence is year by year It is incremented by, and is in the trend of rejuvenation.There are many Western medicine for the treatment of hypertension at present, and Western medicine antihypertensive effect is very fast, but take for a long time easy Drug resistance is generated, and has certain adverse reaction.Chinese medicine effect mitigates, and decompression is steady, and adverse reaction is small, concurrent in prevention and treatment hypertension There is very big advantage in terms of the generation of disease and improvement life in patients.
Summary of the invention
A kind of Chinese medicine of blood pressure lowering of the present invention and preparation method thereof, the Traditional Chinese Medical on Treating Hypertension have significant effect, secondary work With small advantage.It is particularly suitable for the hypertensive patient of liver-yang hyperactivity.
Uncaria energy dispelling pathogenic wind and eliminating phlegm in side, Poria cocos invigorating the spleen for eliminating dampness gas, Rhizoma Gastrodiae is calming the liver to stop the wind, Radix Salviae Miltiorrhizae blood circulation and channel invigorating, and motherwort is mended Liver and kidney benefiting, Li Shui, Radix Angelicae Sinensis can invigorate blood circulation but also enrich blood, and semen plantaginis clearing damp and promoting diuresis, safflower nourishing blood for regulating menstruation, oyster are calming the liver, old Skin dispersing stagnated hepatoqi, Herba Epimedii tonifying kidney and strengthening yang, all medicines are played altogether in side plays calming the liver to stop the wind, the function of blood circulation and channel invigorating.
Technical solution of the present invention is as follows:
A kind of Chinese medicine of blood pressure lowering provided by the invention, is made of the bulk pharmaceutical chemicals of following weight proportion: uncaria 110~ 130 parts, 110~130 parts of Poria cocos, 110~130 parts of Rhizoma Gastrodiae, 80~100 parts of Radix Salviae Miltiorrhizae, 80~100 parts of motherwort, Radix Angelicae Sinensis 80~100 Part, 50~70 parts of semen plantaginis, 50~70 parts of safflower, 50~70 parts of oyster, 50~70 parts of dried orange peel, 50~70 parts of Herba Epimedii.
Chinese medicine for lowering blood pressure of the present invention is made of the bulk pharmaceutical chemicals of following weight proportion are as follows: 120 parts of uncaria, Poria cocos 120 parts, it is 120 parts of Rhizoma Gastrodiae, 90 parts of Radix Salviae Miltiorrhizae, 90 parts of motherwort, 90 parts of Radix Angelicae Sinensis, 60 parts of semen plantaginis, 60 parts of safflower, 60 parts of oyster, old 60 parts of skin, 60 parts of Herba Epimedii.
Preferably, Chinese medicine for lowering blood pressure of the present invention is made of the bulk pharmaceutical chemicals of following weight proportion are as follows: uncaria 130 Part, 130 parts of Poria cocos, 110 parts of Rhizoma Gastrodiae, 80 parts of Radix Salviae Miltiorrhizae, 100 parts of motherwort, 80 parts of Radix Angelicae Sinensis, 70 parts of semen plantaginis, 50 parts of safflower, oyster 70 parts, 70 parts of dried orange peel, 50 parts of Herba Epimedii.
Preferably, Chinese medicine for lowering blood pressure of the present invention is made of the bulk pharmaceutical chemicals of following weight proportion are as follows: uncaria 110 It is part, 110 parts of Poria cocos, 130 parts of Rhizoma Gastrodiae, 100 parts of Radix Salviae Miltiorrhizae, 80 parts of motherwort, 100 parts of Radix Angelicae Sinensis, 50 parts of semen plantaginis, 70 parts of safflower, male 50 parts of oyster, 50 parts of dried orange peel, 70 parts of Herba Epimedii.
Oral preparation made of technical solution of the present invention can be granule, tablet or hard capsule.
Granule: gained Traditional Chinese drug mixture being mixed with suitable dextrin, sucrose, is pelletized, dry, and granule is made.
Tablet: gained Traditional Chinese drug mixture is mixed with appropriate amount of starch, dextrin, granulation is tabletted.
Hard capsule: by gained Traditional Chinese drug mixture, being added suitable auxiliary material, granulation, encapsulated, and hard capsule is made.
The technical solution of the preparation method of Chinese medicine of the present invention is as follows:
Hook taking rattan, Poria cocos, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, motherwort, Radix Angelicae Sinensis, semen plantaginis, safflower, oyster, dried orange peel, Herba Epimedii, using subtracting Pressure constant temperature oven is dried, and drying temperature is 60~80 DEG C, and drying time is 1~3h, and uses common grinder, by drug Be ground into 80~120 mesh fine powders, sieving post-processing is uniformly mixed, sterilizing to get.
Preferably, the technical solution of the preparation method of Chinese medicine of the present invention is as follows:
Hook taking rattan, Poria cocos, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, motherwort, Radix Angelicae Sinensis, semen plantaginis, safflower, oyster, dried orange peel, Herba Epimedii, using subtracting Pressure constant temperature oven is dried, and drying temperature is 60 DEG C, drying time 2h, and uses common grinder, and drug is ground into 100 mesh fine powders, sieving post-processing, be uniformly mixed, sterilizing to get.
Chinese medicine of the present invention the utility model has the advantages that
The present invention is under the guidance of traditional chinese medicine theory and clinical experience, to choose each bulk pharmaceutical chemicals and its proportion, and utilization is all The mutual compatibility combination of position drug, plays synergistic function, plays calming the liver to stop the wind, the function of blood circulation and channel invigorating.Middle medical instrument of the invention It is effective in cure significant, it is easy to industrialized production the advantages of Small side effects.According to clinical verification, Chinese materia medica preparation of the invention is high in treatment The total effective rate of blood pressure is up to 73.6%.
Specific embodiment
It is the specific embodiment of the content of present invention below, for illustrating the skill of the technical problem of being solved in present specification Art scheme facilitates those skilled in the art understand that the content of present invention, but the realization of technical solution of the present invention is not limited to these Embodiment.
Embodiment 1
Hook taking rattan 120g, Poria cocos 120g, Rhizoma Gastrodiae 120g, Radix Salviae Miltiorrhizae 90g, motherwort 90g, Radix Angelicae Sinensis 90g, semen plantaginis 60g, safflower 60g, oyster 60g, dried orange peel 60g, Herba Epimedii 60g are dried using decompression constant temperature oven, and drying temperature is 60 DEG C, when dry Between be 2h, and use common grinder, drug be ground into 100 mesh fine powders, sieving post-processing is uniformly mixed, sterilizing to get.
Embodiment 2
It is hook taking rattan 130g, Poria cocos 130g, Rhizoma Gastrodiae 110g, Radix Salviae Miltiorrhizae 80g, motherwort 100g, Radix Angelicae Sinensis 80g, semen plantaginis 70g, red Flower 50g, oyster 70g, dried orange peel 70g, Herba Epimedii 50g are dried using decompression constant temperature oven, and drying temperature is 80 DEG C, dry Time is 3h, and uses common grinder, drug is ground into 120 mesh fine powders, sieving post-processing is uniformly mixed, sterilizing, i.e., ?.
Embodiment 3
It is hook taking rattan 110g, Poria cocos 110g, Rhizoma Gastrodiae 130g, Radix Salviae Miltiorrhizae 100g, motherwort 80g, Radix Angelicae Sinensis 100g, semen plantaginis 50g, red Flower 70g, oyster 50g, dried orange peel 50g, Herba Epimedii 70g are dried using decompression constant temperature oven, and drying temperature is 60 DEG C, dry Time is 1h, and uses common grinder, and drug is ground into 80 mesh fine powders, and sieving post-processing is uniformly mixed, sterilizing to get.
Embodiment 4
Hook taking rattan 115g, Poria cocos 125g, Rhizoma Gastrodiae 125g, Radix Salviae Miltiorrhizae 95g, motherwort 95g, Radix Angelicae Sinensis 85g, semen plantaginis 65g, safflower 65g, oyster 65g, dried orange peel 65g, Herba Epimedii 65g are dried using decompression constant temperature oven, and drying temperature is 60 DEG C, when dry Between be 2h, and use common grinder, drug be ground into 100 mesh fine powders, sieving post-processing is uniformly mixed, sterilizing to get.
Embodiment 5
Hook taking rattan 125g, Poria cocos 115g, Rhizoma Gastrodiae 115g, Radix Salviae Miltiorrhizae 85g, motherwort 85g, Radix Angelicae Sinensis 95g, semen plantaginis 60g, safflower 60g, oyster 60g, dried orange peel 60g, Herba Epimedii 60g are dried using decompression constant temperature oven, and drying temperature is 60 DEG C, when dry Between be 2h, and use common grinder, drug be ground into 100 mesh fine powders, sieving post-processing is uniformly mixed, sterilizing to get.

Claims (4)

1. a kind of Chinese medicine of blood pressure lowering, which is characterized in that it is made of the bulk pharmaceutical chemicals of following weight proportion: uncaria 110~130 Part, 110~130 parts of Poria cocos, 110~130 parts of Rhizoma Gastrodiae, 80~100 parts of Radix Salviae Miltiorrhizae, 80~100 parts of motherwort, 80~100 parts of Radix Angelicae Sinensis, 50~70 parts of semen plantaginis, 50~70 parts of safflower, 50~70 parts of oyster, 50~70 parts of dried orange peel, 50~70 parts of Herba Epimedii.
2. Chinese medicine as described in claim 1, which is characterized in that it is made of the bulk pharmaceutical chemicals of following weight proportion are as follows: uncaria 120 parts, it is 120 parts of Poria cocos, 120 parts of Rhizoma Gastrodiae, 90 parts of Radix Salviae Miltiorrhizae, 90 parts of motherwort, 90 parts of Radix Angelicae Sinensis, 60 parts of semen plantaginis, 60 parts of safflower, male 60 parts of oyster, 60 parts of dried orange peel, 60 parts of Herba Epimedii.
3. Chinese medicine as described in claim 1, which is characterized in that it is made of the bulk pharmaceutical chemicals of following weight proportion: uncaria 130 Part, 130 parts of Poria cocos, 110 parts of Rhizoma Gastrodiae, 80 parts of Radix Salviae Miltiorrhizae, 100 parts of motherwort, 80 parts of Radix Angelicae Sinensis, 70 parts of semen plantaginis, 50 parts of safflower, oyster 70 parts, 70 parts of dried orange peel, 50 parts of Herba Epimedii.
4. Chinese medicine as described in claim 1, which is characterized in that it is made of the bulk pharmaceutical chemicals of following weight proportion are as follows: uncaria 110 parts, 110 parts of Poria cocos, 130 parts of Rhizoma Gastrodiae, 100 parts of Radix Salviae Miltiorrhizae, 80 parts of motherwort, 100 parts of Radix Angelicae Sinensis, 50 parts of semen plantaginis, 70 parts of safflower, 50 parts of oyster, 50 parts of dried orange peel, 70 parts of Herba Epimedii.
CN201711419967.3A 2017-12-25 2017-12-25 A kind of Chinese medicine of blood pressure lowering and preparation method thereof Pending CN109954088A (en)

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CN201711419967.3A CN109954088A (en) 2017-12-25 2017-12-25 A kind of Chinese medicine of blood pressure lowering and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201711419967.3A CN109954088A (en) 2017-12-25 2017-12-25 A kind of Chinese medicine of blood pressure lowering and preparation method thereof

Publications (1)

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CN109954088A true CN109954088A (en) 2019-07-02

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Country Status (1)

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Application publication date: 20190702