CN109953896A - A kind of dentinal tubule sealer and preparation method thereof - Google Patents
A kind of dentinal tubule sealer and preparation method thereof Download PDFInfo
- Publication number
- CN109953896A CN109953896A CN201711429143.4A CN201711429143A CN109953896A CN 109953896 A CN109953896 A CN 109953896A CN 201711429143 A CN201711429143 A CN 201711429143A CN 109953896 A CN109953896 A CN 109953896A
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- CN
- China
- Prior art keywords
- reagent
- dentinal tubule
- sealer
- tubule sealer
- inorganic filler
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/20—Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
Abstract
The present invention relates to a kind of dentinal tubule sealers and preparation method thereof, the sealer includes reagent A, reagent B and reagent C, the reagent A contains oxalic acid, acrylic acid and styrene sulfonic acid polymers and deionized water, the reagent B contains sodium fluoride, sodium bicarbonate and calcium hydroxide, the reagent C contains inorganic filler, after the reagent A and reagent B dissolution mixing, mixed with the reagent C in the needle tubing for be sealed in shading for subsequent use；Acid etching, bonding composition are effectively integrated into stir-in resin by the sealer provided through the above scheme, without in addition using bonding agent, simplify clinical manipulation, and can obtain excellent repairing effect.
Description
Technical field
The present invention relates to a kind of dental prosthetic materials more particularly to a kind of dentinal tubule sealer and preparation method thereof.
Background technique
The traditional therapy of defect of teeth is to use Dentin bonding (dentin after tooth preparation before modulus
Bonding agent, DBA) closing dentinal tubule, its permeability can be effectively reduced in this way, and it is sensitive to eliminate tooth body.Tradition
DBA closed treating type include total etching three-step approach system, from acid etching two-step method system, saprodontia part is pruned first, shape
After hole, it is coated with dental adhesive material in hole, visible light is irradiated sequentially for the position for being coated with adhesives, makes it
Dental compound resin is filled in solidification in cured layer of adhesive material, finally can to the dental compound resin irradiation of filling
It is light-exposed, make its solidification, not only step is more for such operation, and program is cumbersome, and due to the high viscosity and height of traditional compound resin
The characteristics such as elasticity modulus lead to problems such as there is polymerization shrinkage stress in clinical application greatly and easily in the presence of dead angle is filled, cannot
100% closing completely cuts off leakage；And in the directly reparation of deep dental caries, rebasing, isolation thorn is usually carried out using glass ion at present
Swash, reduces postoperative sensitivity, but its cohesive force between resin then substantially reduces.
Therefore, it develops a kind of easy to operate and is to the enclosure method that it is good that dentine has stronger cohesive force, sealing effect
A research hotspot of dental restorative area at present.
Summary of the invention
The dentinal tubule sealer and other preparation sides that the present invention provides a kind of cementitiousness is strong, sealing effect is good
Method.
In order to solve the above technical problems, the present invention provides a kind of dentinal tubule sealer and preparation method thereof, it is described
A kind of dentinal tubule sealer includes reagent A, reagent B and reagent C, and the constituent of the reagent A is that mass fraction is
2.3% oxalic acid, 5.0% acrylic acid and styrene sulfonic acid polymers and 92.7% deionized water;The composition of the reagent B at
Divide is sodium fluoride (NaF) 0.1% ~ 1.0%, sodium bicarbonate (NaHCO by mass percentage3) solution 97% ~ 99.85%, calcium hydroxide
(Ca (OH)2) 0.05% ~ 2.0%, the NaHCO3Concentration be 0.02 ~ 0.12mol/L, the Ca (OH)2Concentration be 0.1 ~
0.15mol/L；The constituent of the reagent C includes inorganic filler, and the load volume ratio of the inorganic filler is 65%.
In the first possible implementation, the inorganic filler in the reagent C is ytterbium oxide or silica.
It in the second possible implementation, in the reagent C further include tool in conjunction with the first possible implementation
There is the monomer methacryloxypropyl dodecyl bromopyridine of antibacterial activity.
A kind of preparation method of dentinal tubule sealer, specific preparation step include following several steps.
Oxalic acid, base acrylic acid and styrene sulfonic acid polymers are dissolved in deionized water, stirring is centrifuged to being completely dissolved
Washing, obtains the reagent A.
By NaF and Ca (OH)2 It is successively dissolved separately in NaOH solution, under 30 ~ 35 DEG C of water bath with thermostatic control, uniformly stirs
It mixes, the reagent B is obtained by filtration.
The reagent A and the reagent B are stirred evenly into mixing.
The reagent A stirred evenly and the reagent B are mixed in proportion with the reagent C, are put into closing shading
In needle tubing, dentinal tubule sealer is obtained.
The beneficial effects of the present invention are be effectively integrated into acid etching, bonding composition in stir-in resin, without in addition making
With bonding agent, clinical manipulation is simplified, and excellent repairing effect can be obtained；And technical solution operation letter provided by the invention
The single, adhesive strength with superelevation, it is very lasting after filling, durable.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, those skilled in the art obtain every other embodiment under the premise of not making any creative work, all
Belong to the scope of protection of the invention.
A kind of dentinal tubule sealer that specific embodiment provided by the invention provides includes reagent A, reagent B and reagent
C, the constituent of the reagent A be mass fraction be 2.3% oxalic acid, 5.0% acrylic acid and styrene sulfonic acid polymers and
92.7% deionized water;The constituent of the reagent B is sodium fluoride (NaF) 0.1% ~ 1.0%, bicarbonate by mass percentage
Sodium (NaHCO3) solution 97% ~ 99.85%, calcium hydroxide (Ca (OH)2) 0.05% ~ 2.0%, the NaHCO3Concentration be 0.02 ~
0.12mol/L, the Ca (OH)2Concentration be 0.1 ~ 0.15mol/L；The constituent of the reagent C includes inorganic filler,
The load volume ratio of the inorganic filler is 65%.
Wherein the inorganic filler in the reagent C is ytterbium oxide or silica, and further includes having to resist in the reagent C
The active monomer methacryloxypropyl dodecyl bromopyridine of bacterium.
A kind of preparation method of dentinal tubule sealer, specifically includes the following steps: by oxalic acid, base third
Olefin(e) acid and styrene sulfonic acid polymers are dissolved in deionized water, are stirred to being completely dissolved, centrifuge washing obtains the reagent A；
By NaF and Ca (OH)2 It is successively dissolved separately in NaOH solution, under 30 ~ 35 DEG C of water bath with thermostatic control, uniform stirring is filtered
To the reagent B；The reagent A and the reagent B are stirred evenly into mixing；By the reagent A stirred evenly and the examination
Agent B is mixed in proportion with the reagent C, is put into the needle tubing of closing shading, is obtained dentinal tubule sealer.
Specific embodiment one
A kind of dentinal tubule sealer that the present embodiment one provides includes reagent A, reagent B and reagent C, the group of the reagent A
It is the acrylic acid and styrene sulfonic acid polymers and 92.7% deionized water that mass fraction is 2.3% oxalic acid, 5.0% at ingredient;
The constituent of the reagent B is sodium fluoride (NaF) 0.1%, sodium bicarbonate (NaHCO by mass percentage3) solution 99.85%,
Calcium hydroxide (Ca (OH)2) 0.05%, the NaHCO3Concentration be 0.02mol/L, the Ca (OH)2Concentration be 0.15mol/
L；The constituent of the reagent C includes inorganic filler, and the load volume ratio of the inorganic filler is 65%.
Wherein the inorganic filler in the reagent C is ytterbium oxide, and further includes the list with antibacterial activity in the reagent C
Body methacryloxypropyl dodecyl bromopyridine.
Oxalic acid, base acrylic acid and styrene sulfonic acid polymers are dissolved in deionized water, stirring is centrifuged to being completely dissolved
Washing, obtains the reagent A；By NaF and Ca (OH)2 Successively it is dissolved separately in NaOH solution, under 30 DEG C of water bath with thermostatic control,
The reagent B is obtained by filtration in uniform stirring；The reagent A and the reagent B are stirred evenly into mixing；The institute that will be stirred evenly
It states reagent A and the reagent B is mixed in proportion with the reagent C, be put into the needle tubing of closing shading, obtain dentinal tubule envelope
Close agent.
Specific embodiment two
A kind of dentinal tubule sealer that this specific embodiment two provides includes reagent A, reagent B and reagent C, the reagent A
Constituent be mass fraction be 2.3% oxalic acid, 5.0% acrylic acid and styrene sulfonic acid polymers and 92.7% nothing from
Sub- water;The constituent of the reagent B is sodium fluoride (NaF) 1.0%, sodium bicarbonate (NaHCO by mass percentage3) solution
97%, calcium hydroxide (Ca (OH)2) 2.0%, the NaHCO3Concentration be 0.12mol/L, the Ca (OH)2Concentration be
0.1mol/L；The constituent of the reagent C includes inorganic filler, and the load volume ratio of the inorganic filler is 65%.
Wherein the inorganic filler in the reagent C is silica, and further includes having antibacterial activity in the reagent C
Monomer methacryloxypropyl dodecyl bromopyridine.
A kind of preparation method of dentinal tubule sealer, specifically includes the following steps: by oxalic acid, base third
Olefin(e) acid and styrene sulfonic acid polymers are dissolved in deionized water, are stirred to being completely dissolved, centrifuge washing obtains the reagent A；
By NaF and Ca (OH)2 It is successively dissolved separately in NaOH solution, under 30 DEG C of water bath with thermostatic control, institute is obtained by filtration in uniform stirring
State reagent B；The reagent A and the reagent B are stirred evenly into mixing；The reagent A stirred evenly and the reagent B is same
The reagent C mixes in proportion, is put into the needle tubing of closing shading, obtains dentinal tubule sealer.
Specific embodiment three
A kind of dentinal tubule sealer that this specific embodiment three provides includes reagent A, reagent B and reagent C, the reagent A
Constituent be mass fraction be 2.3% oxalic acid, 5.0% acrylic acid and styrene sulfonic acid polymers and 92.7% nothing from
Sub- water;The constituent of the reagent B is sodium fluoride (NaF) 0.5%, sodium bicarbonate (NaHCO by mass percentage3) solution
98%, calcium hydroxide (Ca (OH)2) 1.5%, the NaHCO3Concentration be 0.1mol/L, the Ca (OH)2Concentration be
0.12mol/L；The constituent of the reagent C includes inorganic filler, and the load volume ratio of the inorganic filler is 65%.
Wherein the inorganic filler in the reagent C is ytterbium oxide, and further includes the list with antibacterial activity in the reagent C
Body methacryloxypropyl dodecyl bromopyridine.
A kind of preparation method of dentinal tubule sealer, specifically includes the following steps: by oxalic acid, base third
Olefin(e) acid and styrene sulfonic acid polymers are dissolved in deionized water, are stirred to being completely dissolved, centrifuge washing obtains the reagent A；
By NaF and Ca (OH)2 It is successively dissolved separately in NaOH solution, under 32 DEG C of water bath with thermostatic control, institute is obtained by filtration in uniform stirring
State reagent B；The reagent A and the reagent B are stirred evenly into mixing；The reagent A stirred evenly and the reagent B is same
The reagent C mixes in proportion, is put into the needle tubing of closing shading, obtains dentinal tubule sealer.
Through the above technical solutions, acid etching, bonding composition are effectively integrated into stir-in resin, without in addition using viscous
Agent is connect, simplifies clinical manipulation, and excellent repairing effect can be obtained；And technical solution provided by the invention is easy to operate, tool
There is the adhesive strength of superelevation, it is very lasting after filling, durable.
A kind of dentinal tubule sealer and preparation method thereof is provided for the embodiments of the invention above to have carried out in detail
It introduces, specific case used herein is expounded technical solution of the present invention, and above embodiments are only of the invention
Preferred embodiment is not intended to limit the scope of protection of the present invention, for those of ordinary skill in the art, in the present invention
Technical scope in the thinkable variation of institute or improvement, should be covered by the protection scope of the present invention.
Claims (4)
1. a kind of dentinal tubule sealer, which is characterized in that including reagent A, reagent B and reagent C, the composition of the reagent A
Ingredient is the acrylic acid and styrene sulfonic acid polymers and 92.7% deionized water that mass fraction is 2.3% oxalic acid, 5.0%;
The constituent of the reagent B is sodium fluoride (NaF) 0.1% ~ 1.0%, sodium bicarbonate (NaHCO by mass percentage3) solution
97% ~ 99.85%, calcium hydroxide (Ca (OH)2) 0.05% ~ 2.0%, the NaHCO3Concentration be 0.02 ~ 0.12mol/L, the Ca
(OH)2Concentration be 0.1 ~ 0.15mol/L；
The constituent of the reagent C includes inorganic filler, and the load volume ratio of the inorganic filler is 65%.
2. a kind of dentinal tubule sealer according to claim 1, which is characterized in that inorganic in the reagent C is filled out
Material is ytterbium oxide or silica.
3. a kind of dentinal tubule sealer according to claim 1, which is characterized in that further include tool in the reagent C
There is the monomer methacryloxypropyl dodecyl bromopyridine of antibacterial activity.
4. a kind of preparation method of dentinal tubule sealer, which is characterized in that specific preparation process is as follows for it:
Oxalic acid, base acrylic acid and styrene sulfonic acid polymers are dissolved in deionized water, are stirred to being completely dissolved, centrifugation is washed
It washs, obtains the reagent A；
By NaF and Ca (OH)2 Successively it is dissolved separately in NaOH solution, under 30 ~ 35 DEG C of water bath with thermostatic control, uniform stirring, mistake
Filter obtains the reagent B；
The reagent A and the reagent B are stirred evenly into mixing；
The reagent A stirred evenly and the reagent B are mixed in proportion with the reagent C, are put into the needle tubing of closing shading
In, obtain dentinal tubule sealer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711429143.4A CN109953896A (en) | 2017-12-26 | 2017-12-26 | A kind of dentinal tubule sealer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711429143.4A CN109953896A (en) | 2017-12-26 | 2017-12-26 | A kind of dentinal tubule sealer and preparation method thereof |
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| Publication Number | Publication Date |
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| CN109953896A true CN109953896A (en) | 2019-07-02 |
Family
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| CN201711429143.4A Pending CN109953896A (en) | 2017-12-26 | 2017-12-26 | A kind of dentinal tubule sealer and preparation method thereof |
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Citations (8)
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|---|---|---|---|---|
| JPH05255029A (en) * | 1992-03-11 | 1993-10-05 | G C:Kk | Composition for treating tooth plane |
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| CN103239476A (en) * | 2013-05-23 | 2013-08-14 | 关晴光 | Sushuang bioactivity mineral powder as well as preparation method and application thereof |
| CN103491929A (en) * | 2011-02-03 | 2014-01-01 | 塞拉韦尔生物技术简易股份公司 | Dental cement composition |
| CN103876945A (en) * | 2014-04-17 | 2014-06-25 | 厦门大学 | Dentinal-tubule sealing agent and preparation method thereof |
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|---|---|---|---|---|
| JPH05255029A (en) * | 1992-03-11 | 1993-10-05 | G C:Kk | Composition for treating tooth plane |
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| CN106132421A (en) * | 2014-03-21 | 2016-11-16 | 欧米亚国际集团 | The calcium carbonate through surface reaction for desensitizing dental |
| CN103876945A (en) * | 2014-04-17 | 2014-06-25 | 厦门大学 | Dentinal-tubule sealing agent and preparation method thereof |
| CN106974834A (en) * | 2017-04-01 | 2017-07-25 | 首都医科大学附属北京口腔医院 | A kind of utilization deferred reaction forms material and its application of mineral matter in dentinal tubule |
| CN107362052A (en) * | 2017-06-30 | 2017-11-21 | 常州思宇知识产权运营有限公司 | A kind of sensitive teeth dentinal tubule sealer and preparation method thereof |
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Application publication date: 20190702 |
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