CN109938987B - Tic disorder therapeutic device placed in oral cavity - Google Patents
Tic disorder therapeutic device placed in oral cavity Download PDFInfo
- Publication number
- CN109938987B CN109938987B CN201910197837.2A CN201910197837A CN109938987B CN 109938987 B CN109938987 B CN 109938987B CN 201910197837 A CN201910197837 A CN 201910197837A CN 109938987 B CN109938987 B CN 109938987B
- Authority
- CN
- China
- Prior art keywords
- tongue
- oral cavity
- contacts
- fixing parts
- connecting part
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000000214 mouth Anatomy 0.000 title claims abstract description 37
- 230000001225 therapeutic effect Effects 0.000 title abstract description 13
- 208000016686 tic disease Diseases 0.000 title abstract description 13
- 210000004556 brain Anatomy 0.000 abstract description 16
- 210000003205 muscle Anatomy 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 8
- 230000003387 muscular Effects 0.000 abstract description 6
- 210000005036 nerve Anatomy 0.000 abstract description 6
- 208000035475 disorder Diseases 0.000 abstract description 4
- 230000004936 stimulating effect Effects 0.000 abstract description 4
- 206010028347 Muscle twitching Diseases 0.000 abstract description 3
- 210000004400 mucous membrane Anatomy 0.000 abstract description 3
- 238000005086 pumping Methods 0.000 abstract description 3
- 230000003252 repetitive effect Effects 0.000 abstract description 3
- 210000002435 tendon Anatomy 0.000 abstract description 3
- 206010049816 Muscle tightness Diseases 0.000 abstract description 2
- 208000036366 Sensation of pressure Diseases 0.000 abstract description 2
- 230000008602 contraction Effects 0.000 abstract description 2
- 238000011282 treatment Methods 0.000 description 20
- 230000000638 stimulation Effects 0.000 description 11
- 238000000034 method Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 201000010099 disease Diseases 0.000 description 4
- 238000012549 training Methods 0.000 description 4
- 238000011491 transcranial magnetic stimulation Methods 0.000 description 4
- 208000023655 Tic Diseases 0.000 description 3
- 208000008234 Tics Diseases 0.000 description 3
- 208000000323 Tourette Syndrome Diseases 0.000 description 3
- 208000016620 Tourette disease Diseases 0.000 description 3
- 239000000164 antipsychotic agent Substances 0.000 description 3
- 229940005529 antipsychotics Drugs 0.000 description 3
- 230000003542 behavioural effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 208000012902 Nervous system disease Diseases 0.000 description 2
- 208000025966 Neurological disease Diseases 0.000 description 2
- 230000001149 cognitive effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000004007 neuromodulation Effects 0.000 description 2
- 210000002027 skeletal muscle Anatomy 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- CEUORZQYGODEFX-UHFFFAOYSA-N Aripirazole Chemical compound ClC1=CC=CC(N2CCN(CCCCOC=3C=C4NC(=O)CCC4=CC=3)CC2)=C1Cl CEUORZQYGODEFX-UHFFFAOYSA-N 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 201000004311 Gilles de la Tourette syndrome Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- JTVPZMFULRWINT-UHFFFAOYSA-N N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide Chemical compound CCN(CC)CCNC(=O)C1=CC(S(C)(=O)=O)=CC=C1OC JTVPZMFULRWINT-UHFFFAOYSA-N 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 230000000561 anti-psychotic effect Effects 0.000 description 1
- 229960004372 aripiprazole Drugs 0.000 description 1
- 208000013404 behavioral symptom Diseases 0.000 description 1
- 238000013542 behavioral therapy Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000030214 innervation Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000004526 pharmaceutical effect Effects 0.000 description 1
- 239000000955 prescription drug Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000008430 psychophysiology Effects 0.000 description 1
- 238000001671 psychotherapy Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000003319 supportive effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 229960005344 tiapride Drugs 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000001755 vocal effect Effects 0.000 description 1
Landscapes
- Orthopedics, Nursing, And Contraception (AREA)
- Finger-Pressure Massage (AREA)
Abstract
The invention relates to the field of medical appliances, and provides a pumping disorder therapeutic device placed in an oral cavity. The connecting part is connected to one opposite side of the two fixing parts, the shape of the connecting part is adapted to the shape of the inner wall of part of the oral cavity between the two fixing parts, and a plurality of contacts are arranged on one side of the connecting part facing to the tongue. With these contacts, a sensation of pressure can be created on the tongue surface, and the resulting stimulus constantly adjusts the degree of muscular tension innervated by the brain when the mouth is stationary; when the oral cavity is active, the intensity of the stimulating signal formed by the contact is increased, and the regulation of the brain on the muscle tension degree is enhanced; thereby reducing the occurrence of 'short, rapid, repetitive muscle twitches'; the brain center is excited by the biting force of the upper jaw and the lower jaw, the movement muscles of the oral cavity skeletons, the tendons and the mucous membrane, the output of the nerve information is adjusted by active feedback, and the movement tension and the contraction frequency of the tic disorder muscle group are adjusted.
Description
Technical Field
The invention relates to the field of medical appliances, in particular to a pumping disorder therapeutic device placed in an oral cavity.
Background
Tic Disorders (TDs) are the most common group of neurological disorders that occur in childhood and adolescence. Clinically, it can be classified into 3 types: transient tic disorders (also known as tic disorders), chronic motor or vocal tic, tourette's syndrome (Tourette Syndrome, TS, tourette's syndrome), i.e., a combination of vocal and multiple motor tic disorders, most typically represented by TS. The motor tic and/or vocal tic (including dry cough, throat, nasal inhalation, etc.) of one or more parts, which are mainly involuntary, repetitive and rapid, may be accompanied by inattention, hyperactivity, compulsive movements or thinking and other behavioral symptoms. Mainly represents involuntary, purposeless, repetitive and rapid contractive movements; the pathogenesis is not yet defined. The incidence rate is 0.5-1/10 ten thousand, and the ratio of men to women is 3-5:1. The disease is long in duration, generally more than 1 year, and can last for 10 years or more, and has strong fluctuation, obvious time-hidden time, but mostly disappears before and after puberty. Lasting to adults, the severity of the twitch is also lessened.
The family and society burden that this disease brought is huge, brings huge psychological burden to children teenager oneself simultaneously, is unfavorable for the growth and the achievement of infant.
The etiology of this disease has not been elucidated and recent studies suggest that the disorder may interact with genetic factors, neurobiochemical factors, neuroimmunological factors, stress, environmental factors, etc. as a result of the childhood development.
Currently there is a lack of effective therapeutic drugs and means.
Current treatments for this disease include antipsychotics such as tiapride, aripiprazole, psychotherapy, behavioral therapy, and neuromodulation therapy. The use of antipsychotics is from initial dose, therapeutic dose, maintenance dose, to decrement until withdrawal, and must be performed following the order. The non-drug treatment requires more cooperation and investment of guardians.
Nevertheless, the therapeutic effect on TD is limited. The outstanding manifestations are:
1. parents have a number of concerns about the administration of antipsychotics to children during the growth phase, including adverse effects caused by the impact on normal growth and development. And as an antipsychotic drug for prescription drugs, it is often necessary to take a child patient to visit a mental hospital, who would make the child and people around family members feel "shame" as the child patient or the person himself suffers from mental diseases. Many infants are therefore in a state without any treatment.
2. As one of the most common neurological disorders, the existing non-pharmaceutical effects are very limited.
The prior non-drug treatment mainly comprises psychological treatment, behavioral treatment and nerve regulation treatment, including various psychological behavior treatment methods such as education, habit reversal training, prosody exercise, positive reinforcement, relaxation training, negative exercise method, self-supervision method, cognitive behavior treatment and the like, and transcranial magnetic stimulation treatment.
2.1 Psychological treatment
Including supportive psychological therapy, home intervention, and school intervention.
2.2 Behavioural treatment
Various behavioral intervention methods have been applied to treat TD and have achieved good results. Mainly comprises positive strengthening, regression method, intensive exercise, relaxation training, self-supervision, function or situation management method based, habit reversal training, exposure of effect prevention and cognitive behavior treatment.
2.3 Neuromodulation therapy
Nerve regulation and control treatment methods such as brain electrical biofeedback, deep brain stimulation, transcranial magnetic stimulation and the like are increasingly focused by a plurality of researchers at home and abroad, but the curative effect is not clear. Moreover, deep brain stimulation is an invasive technique, and is expensive, curative effects are to be observed, and the infants and family members are generally unacceptable.
To sum up, current treatments for TS are currently lacking in effective and acceptable therapeutic techniques.
At present, nerve regulation and control treatment methods such as brain electrical biofeedback, deep brain stimulation, transcranial magnetic stimulation and the like are used for treating TS. The therapeutic effect of the electroencephalogram biofeedback treatment TS is extremely limited, and the effect thereof has not been accepted by the International authorities- -the Association of Applied Psychophysiology and Biofeedback (AAPB) and the International Association of neurobiofeedback research (ISNR) - -.
Deep brain stimulation is an invasive technique, is expensive, has a curative effect to be observed, and is generally unacceptable to children and families.
The stimulation part, the stimulation frequency, the stimulation intensity and the stimulation treatment course of the transcranial magnetic stimulation treatment TS are not clear, and the medical institution of the infant is required to carry out the treatment, and the key is that adverse reactions such as large noise, headache, dizziness and the like are also caused, so that the therapeutic device is difficult to be accepted by the infant and family members clinically.
Disclosure of Invention
In order to solve the above technical problems or at least partially solve the above technical problems, the present application provides a tic disorder therapeutic apparatus placed in an interior of an oral cavity.
The invention provides a pumping disorder therapeutic device placed in an oral cavity, which comprises two fixing parts with U-shaped sections sleeved on teeth and/or gums at two sides of an upper jaw or a lower jaw, wherein a connecting part is connected between one opposite sides of the two fixing parts, the shape of the connecting part is matched with the shape of part of the inner wall of the oral cavity between the two fixing parts, and a plurality of contacts are arranged on at least one of the connecting part and the two fixing parts.
Optionally, a plurality of contacts are arranged on one side of the connecting part facing the tongue.
Optionally, one side of the connecting part facing away from the tongue is provided with a plurality of contacts
Optionally, the outer wall of one side of at least one fixing part facing away from the tongue is provided with a plurality of contacts.
Optionally, the connecting portion is connected at the U-shaped edge of two fixed portions, and at least one side of fixed portion towards the tongue is equipped with a plurality of contacts.
Optionally, at least part of the fixing part is sleeved on the gum, and a plurality of contacts are arranged on the inner wall of the part of the fixing part corresponding to the gum.
Optionally, the contact is a bump.
Optionally, a contact extending towards the bottom direction of the U-shaped fixing part is arranged at the edge of one side of at least one fixing part facing away from the tongue, and a plurality of contacts are arranged at one side of the contact facing away from the tongue and/or one side facing the tongue.
Optionally, the length of the extending contact is greater than the height of the fixing portion.
Optionally, the contact has elasticity.
With several contacts provided on at least one of the connecting part and the two fixing parts, it is possible to create a impression of the tongue and/or the inner wall of the mouth, these contacts "actively" creating a tactile and impression tension to the tongue and/or the muscles of the mouth when the mouth is stationary, these tensions as stimuli, constantly regulating the degree of muscular tension of the brain innervation; the strength of the stimulation signals of the touch sense and the pressure sense generated by the bulges is increased when the oral cavity is active or moves, so that the regulation of the muscular tension degree by the brain is enhanced; the occurrence of 'short-lived, rapid and repeated muscle twitches', especially the activities of expressive muscles and skeletal muscles of the head and the face, are reduced through the regulation of the muscular tension degree by the brain; the oral cavity skeleton exercise excites muscles, tendons and mucous membrane to excite brain centers through the biting force of the upper jaw and the lower jaw, the active feedback is used for adjusting the output of nerve information, adjusting the oral cavity exercise tension and adjusting the exercise tension and the contraction frequency of the tic disorder muscle group.
Drawings
FIG. 1 is a schematic view of a tic disorder therapeutic apparatus placed inside an oral cavity according to an embodiment of the present invention;
Fig. 2 is a schematic view of another view of a tic disorder therapeutic apparatus placed inside an oral cavity according to an embodiment of the present invention.
Reference numerals:
1. a fixing part; 2. a connection part; 3. and a contact.
Detailed Description
In order that the above-recited objects, features and advantages of the present invention can be more clearly understood, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. It is to be understood that the depicted embodiments are some, but not all, embodiments of the present invention. The specific embodiments described herein are to be considered in an illustrative rather than a restrictive sense. All other embodiments, which are obtained by a person skilled in the art based on the described embodiments of the invention, fall within the scope of protection of the invention.
Referring to fig. 1 and 2, the device for treating tic disorder provided by the embodiment of the invention comprises two fixing parts 1 with U-shaped cross sections sleeved on teeth and/or gum at two sides of an upper jaw or a lower jaw, wherein a connecting part 2 is connected between one opposite sides of the two fixing parts 1, the shape of the connecting part 2 is adapted to the shape of part of the inner wall of the oral cavity between the two fixing parts 1, wherein for children with teeth not yet growing fully or in a tooth picking stage, one part of the fixing parts 1 can be sleeved on the teeth, and the other part of the fixing parts 1 can be sleeved on the tooth bed; the connecting part 2 is positioned above the tongue in the case that the fixing part 1 is sleeved on the teeth and/or gums of the upper jaw, and the connecting part 2 is positioned below the tongue in the case that the fixing part 1 is sleeved on the teeth and/or gums of the lower jaw; the fixing parts 1 form a certain connecting force with the teeth and/or the gum by a sleeving manner, and the connecting parts 2 are used for fixing the relative positions of the two fixing parts 1, and can also be attached to the inner wall of the upper jaw or the lower jaw due to the adaptation of the shape to the inner wall of the oral cavity, and form a certain connecting force with the upper jaw or the lower jaw by utilizing the atmospheric pressure, so that the whole therapeutic apparatus is stably fixed on the upper tooth or the lower tooth.
The connecting part 2 and at least one of the two fixing parts 1 are provided with a plurality of contacts, and the contacts can be convex points protruding outwards or concave pits recessed inwards, and can be of any other shape, so long as the contact between the tongue and the connecting part can generate touch sense different from the contact of a smooth surface. The contacts act to create a sensation of pressure on the inner walls of the mouth and/or the upper or lower surface of the tongue, and when the mouth is at rest, these contacts "actively" create tactile and compressive tensions on the mouth and/or tongue muscles which act as stimuli, constantly regulating the degree of muscular tension innervated by the brain; when the oral cavity moves or moves, the intensity of the stimulation signals generated by the bulges is increased, so that the regulation of the brain on the muscle tension degree is enhanced; the occurrence of 'short-lived, rapid and repeated muscle twitches', especially the activities of expressive muscles and skeletal muscles of the head and the face, are reduced through the regulation of the muscular tension degree by the brain; the biting force of the upper jaw and the lower jaw excites muscles, tendons and mucous membrane through oral bone movement to excite brain centers, and the output of nerve information is actively fed back and regulated to regulate the oral movement tension.
In some embodiments, the side of the connection facing the tongue is provided with a number of contacts that create a stimulus to the upper or lower surface of the tongue, thereby producing a tactile and compressive stimulus to the tongue muscles.
In some embodiments, the side of the connection facing away from the tongue is provided with contacts for stimulating the inner wall of the mouth above or below the tongue.
In some embodiments, the outer wall of the side of at least one of the fixing portions 1 facing away from the tongue is provided with contacts for stimulating the inner wall of the mouth outside the teeth, thereby stimulating more muscle groups in the mouth.
In some embodiments, the connecting part 2 is connected to the U-shaped edges of the two fixing parts 1, so that the connecting part 2 and the fixing parts 1 are in smooth transition, discomfort is not caused to the oral cavity modeling, and the connecting part 2 can be exposed towards one side wall of the tongue; in addition, the side of the at least one fixing portion 1 facing the tongue is provided with several contacts, thereby creating a compressive tension to the side of the tongue.
In some embodiments, at least part of the fixing portion 1 is sleeved on the gum, and a part of the inner wall of the fixing portion 1 corresponding to the gum is provided with a plurality of contacts so as to form stimulation on the part of the gum.
Since the fixing portion 1 is in a socket-joint relationship with the teeth or gums, the outer contour of the fixing portion 1 substantially coincides with the contour of the teeth or gums, and therefore if only a plurality of contacts are provided on the side of the fixing portion 1 facing away from the tongue, these contacts cannot form a stimulus of a large extent and intensity with the inner wall of the oral cavity. Therefore, in this embodiment, the contact piece 3 extending towards the bottom direction of the U-shape of the fixing portion is disposed at the edge of the side of the at least one fixing portion 1 facing away from the tongue, and a plurality of contacts are disposed at the side of the contact piece 3 facing toward and/or facing away from the tongue, so that the contact piece 3 with the contacts can form a larger area and stronger contact with the inner wall of the oral cavity.
Further, the length of extension of the contact piece 3 is greater than the height of the fixing part 1, so that when the oral cavity is closed, the contact point on the contact piece 3 can be contacted with the inner wall of the oral cavity corresponding to the lower teeth, and can be contacted with the inner wall of the oral cavity corresponding to the upper teeth.
In addition, the contact 3 is preferably elastic so that a greater force of contact with the inner wall of the mouth can be made using the elastic force and no uncomfortable feeling is caused to the mouth.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.
Claims (3)
1. The device is characterized by comprising two U-shaped fixing parts sleeved on teeth and/or gums at two sides of an upper jaw or a lower jaw, wherein a connecting part is connected between one opposite sides of the two fixing parts, the shape of the connecting part is matched with the shape of part of the inner wall of the oral cavity between the two fixing parts, a plurality of contacts are arranged at one side of the connecting part facing the tongue and the side facing away from the tongue, and a plurality of contacts are arranged at one side of the two fixing parts facing the tongue and the side facing away from the tongue;
The edge of one side of the two fixing parts, which is away from the tongue, is provided with a contact piece extending towards the U-shaped bottom of the fixing parts, and one side of the contact piece, which is away from the tongue, and one side of the contact piece, which is towards the tongue, are provided with a plurality of contacts; the length of the extending contact piece is larger than the height of the fixing part;
at least part of the fixing part is sleeved on the gum, and a plurality of contacts are arranged on the inner wall of the part of the fixing part corresponding to the gum;
the contact has elasticity.
2. The device according to claim 1, wherein the connecting portion is connected to the U-shaped edges of the two fixing portions.
3. The device according to claim 1, wherein the contact is a bump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910197837.2A CN109938987B (en) | 2019-03-15 | 2019-03-15 | Tic disorder therapeutic device placed in oral cavity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910197837.2A CN109938987B (en) | 2019-03-15 | 2019-03-15 | Tic disorder therapeutic device placed in oral cavity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109938987A CN109938987A (en) | 2019-06-28 |
| CN109938987B true CN109938987B (en) | 2024-06-04 |
Family
ID=67009956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910197837.2A Active CN109938987B (en) | 2019-03-15 | 2019-03-15 | Tic disorder therapeutic device placed in oral cavity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109938987B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5584687A (en) * | 1993-08-09 | 1996-12-17 | E-Z Gard Industries, Inc. | Performance enhancing dental appliance |
| US5624257A (en) * | 1991-10-31 | 1997-04-29 | Farrell; Christopher J. | Oral appliance |
| US5865619A (en) * | 1993-08-09 | 1999-02-02 | Big Picture, Inc. | Triple composite performance enhancing dental appliance |
| US6371758B1 (en) * | 1996-08-05 | 2002-04-16 | Bite Tech, Inc. | One-piece customizable dental appliance |
| CN101801305A (en) * | 2007-09-14 | 2010-08-11 | 畸齿矫正圣何塞杜马冯世界研究所 | Face and mouth muscle stimulator |
| KR20170064555A (en) * | 2010-12-22 | 2017-06-09 | 페이트 세러퓨틱스, 인코포레이티드 | Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs |
| CN210170424U (en) * | 2019-03-15 | 2020-03-24 | 首都医科大学宣武医院 | Tic disorder therapeutic device placed in oral cavity |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7404403B2 (en) * | 1998-12-16 | 2008-07-29 | Christopher John Farrell | Oral appliance |
| US20020082493A1 (en) * | 2000-12-27 | 2002-06-27 | Anuthep Benja-Athon | Precise and correct method of treating dystonia |
| US6820623B2 (en) * | 2002-11-14 | 2004-11-23 | Bite Tech, Inc. | Polyethylene dental appliance and mouthguard with tactifier resin |
| US20080202530A1 (en) * | 2007-02-15 | 2008-08-28 | Sims Anthony B | Device and Method for the Treatment of Movement Disorders |
| US9968419B2 (en) * | 2010-06-23 | 2018-05-15 | Ramiro Michael Alvarez | Method and oral appliance for improving air intake and reducing bruxism |
| US20150173935A1 (en) * | 2012-07-23 | 2015-06-25 | University Of Washington Through Its Center For Commercialization | Oral orthoses and associated devices, systems, and methods |
| US20160120619A1 (en) * | 2014-10-29 | 2016-05-05 | Brian K. Bons | Orthotic Device |
-
2019
- 2019-03-15 CN CN201910197837.2A patent/CN109938987B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5624257A (en) * | 1991-10-31 | 1997-04-29 | Farrell; Christopher J. | Oral appliance |
| US5584687A (en) * | 1993-08-09 | 1996-12-17 | E-Z Gard Industries, Inc. | Performance enhancing dental appliance |
| US5865619A (en) * | 1993-08-09 | 1999-02-02 | Big Picture, Inc. | Triple composite performance enhancing dental appliance |
| US6371758B1 (en) * | 1996-08-05 | 2002-04-16 | Bite Tech, Inc. | One-piece customizable dental appliance |
| CN101801305A (en) * | 2007-09-14 | 2010-08-11 | 畸齿矫正圣何塞杜马冯世界研究所 | Face and mouth muscle stimulator |
| KR20170064555A (en) * | 2010-12-22 | 2017-06-09 | 페이트 세러퓨틱스, 인코포레이티드 | Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs |
| CN210170424U (en) * | 2019-03-15 | 2020-03-24 | 首都医科大学宣武医院 | Tic disorder therapeutic device placed in oral cavity |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109938987A (en) | 2019-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Chen et al. | The Cambridge Neurological Inventory: a clinical instrument for assessment of soft neurological signs in psychiatric patients | |
| Kiziltan et al. | Stuttering may be a type of action dystonia | |
| Williams | Traumatic brain injury | |
| AU2020102546A4 (en) | Interactive gaming device for cerebral palsy intervention, treatment and management and its method thereof | |
| CN210170424U (en) | Tic disorder therapeutic device placed in oral cavity | |
| CN109938987B (en) | Tic disorder therapeutic device placed in oral cavity | |
| CN210170425U (en) | Tic disorder therapeutic device placed in oral cavity | |
| Luthe | About the methods of autogenic therapy | |
| Lee et al. | Exploratory investigation of the effects of tactile stimulation using air pressure at the auricular vagus nerve on heart rate variability | |
| Pearcey et al. | What lies beneath the brain: Neural circuits involved in human locomotion | |
| Paddison et al. | Spinal cord injury | |
| RU2122443C1 (en) | Method of correcting neuro-mental diseases accompanied with locomotive disturbances | |
| Jakubowska et al. | The interdisciplinarity and innovativeness of methods in rehabilitation of children with cerebral palsy | |
| Öst | Applied relaxation | |
| CN109938988A (en) | It is placed in the tic disorder therapeutic equipment of cavity interior | |
| Lu et al. | Anxiety control of dental patients by clinical combination of acupuncture, Bi-Digital O-Ring Test, and eye movement desensitization with sedation via submucosal route | |
| Azam | Efficacy of Stomatognathic Alignment Exercise Program on Mouth Opening Limitation Improvement in Spastic Myogenic Temporomandibular Disorder of Hemiparetic Cerebral Palsy Children | |
| Gnanavel et al. | Management of Autism through Yoga-A systematic review | |
| Jayavelu et al. | Effect of Periglossal Electrical Stimulation on Haemodynamic Parameters in Stroke Patients-An Experimental Study | |
| Mitsumoto | The clinical features and prognosis of amyotrophic lateral sclerosis | |
| Rajput et al. | Immediate Effect of Nadishodhana Pranayama on Functional Mobility in Stroke Patients | |
| Nusser-Müller-Busch | The FOTT Approach: Functional–Complex–Relevant for Daily Life | |
| Vinski et al. | Mesenchymal Stem Cell Therapy in the Management of Cerebral Palsy (CP): A Promising Intervention for Functional Improvement | |
| Sharma et al. | Journal of Neurorestoratology | |
| RU2141352C1 (en) | Method of psychophysical training of health |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |