CN109938033A - A kind of bactericidal composition and application containing benziothiazolinone and oxolinic acid - Google Patents
A kind of bactericidal composition and application containing benziothiazolinone and oxolinic acid Download PDFInfo
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- CN109938033A CN109938033A CN201910307324.2A CN201910307324A CN109938033A CN 109938033 A CN109938033 A CN 109938033A CN 201910307324 A CN201910307324 A CN 201910307324A CN 109938033 A CN109938033 A CN 109938033A
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Abstract
The invention discloses a kind of combination germicide containing benziothiazolinone and oxolinic acid, includes effective component benziothiazolinone and oxolinic acid, and the mass ratio of benziothiazolinone and oxolinic acid is 60-1:1-60.The combination germicide can be applied to the various bacterial disease of prevention and treatment fruit tree, vegetables, cereal crop, has obvious synergistic function, has delayed the drug resistance of pathogen, and the lasting period is long, reduces times for spraying and dosage, reduces use cost.Combination germicide of the present invention can be used for preventing and treating the diseases such as cucumber bacterial angular leaf spot, bacterial wilt of tomato, bacterial soft rot of potato, mango bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, canker of pear and Prospect on Kiwifruit Bacterial Canker, significant effect.
Description
Technical field
The present invention relates to agricultural disease prevention and control field, specifically a kind of bactericidal composition containing benziothiazolinone and oxolinic acid and answer
With.
Background technique
Benziothiazolinone (Benziothiazolinone) is the heterocyclic of Shaanxi Xida Huate Science & Technology Industrial Co., Ltd.'s exploitation
Fungicide.Molecular formula: C7H5NOS, chemical name: 1,2 benzisothiazole-3-ketone.Benziothiazolinone is a kind of efficient, low toxicity, wide spectrum
Property fungicide, pathogen cell membrane protein and synthesis system can be destroyed, so that pathogen be inhibited to breed, interference pathogen is thin
Born of the same parents' metabolism, makes its physiologic derangement, causes pathogen dead.The compound is to bacterium, fungus-caused multiple kinds of crops disease
Evil has good control efficiency, and fool proof to crops and environment, low toxicity, noresidue.
Oxolinic acid (pyraoxystrobin), chemical name: (1- ethyl -6,7- methylene oxygroup -4- copper 8-hydroxyquinolinate -3- carboxylic acid,
Molecular formula: C13H11NO5, oxolinic acid category second generation quinolinones fungicide, the antibacterial activity to gram-negative bacteria with wide scope,
But it is weaker to the activity of gram positive bacteria, it is inactive to fungi.Mechanism of action is by inhibiting DNA helicase to influence DNA
Normal morphology and function (normal replication) and achieve the purpose that antibacterial, DNA be by high degree of spiral crimp fold in the form of exist
In in thallus, if do not rolled up poly-.Then its length can not be contained in cell wall at all considerably beyond the several times of cell, also without
The normal DNA replication dna of method, transhipment and recombination.The effect of DNA helicase is exactly the poly- state of volume for making DNA keep height, due to quinoline
Promise ketone antibacterial belongs to efficient, low dose of drug, can be used for the thin of rice, vegetables (cabbage, potato), fruit (apple) etc.
Bacterium preventing and curing infection.For rice paddy seed processing, referred to as there is tall and erect effect to the refractory withered bacterial disease of disease paddy of rice (seedling rot disease)
First fungicide.It can also be used to prevent and treat rice Maize Ear Rot, the black chamber disease of potato, soft rot, fire blast and similar disease.Such as exist
Rice heading stage is with 300-600g effective component/hm2Foliage-spray can prevent and treat rice Maize Ear Rot；With 300~600g effective component/
hm2Foliage-spray can prevent and treat the fire blast and soft rot of apple and pears.Also there are protection well and treatment to make to soft rot of cabbage
With.
Cucumber bacterial angular leaf spot (Pseudomonas syringae pv.lachrymans), is the important disease on cucumber
One of evil, often mixes generation with cucumber downy mildew in field, and scab relatively, is sometimes prone to obscure, but cucumber downy mildew is sent out
Sick initial stage generates several water stain shape scabs of polygonal in vacuum side of blade, and bacterial angular leaf spot is needle-shaped water stain in vacuum side of blade generation
Shape scab, often tens scabs occur simultaneously.State of an illness occurrence tendency does not have that downy mildew is rapid, influences cucumber growth without frost
Mildew is serious.Pathogen is in the soil or overwintering with infected seed with invalid body, is next year primary infection bacterium source.Disease on seed
Bacterium can survive 1~2 year in kind of skin and Interior Seed, after planting directly infect cotyledon, and germ breeds in iuntercellular, borrow rainwater anti-
It splashes, ceiling droplet whereabouts, the spread in china such as insect, is invaded from host's nature aperture and wound, occurred after 7-10 days incobations sick
Spot generates bacterial ooze when moist.
Bacterial wilt of tomato (Pseudomonas solanacearum) is fibrovascular system venereal disease evil common on tomato
One, various regions generally occur, and protecting field, open country can occur.The southern and rainy time occurs universal and serious.It is made when falling ill serious
It is died at plant blueness is withered, Severe Reduction is caused even to have no harvest.Bacterial wilt is a kind of bacterial disease that will lead to complete stool wilting, when
30 centimetres of tomato plant height or so, bacterial wilt strain starts aobvious disease；Top blade was wilted sagging before this, and rear lower blade is wilting, middle part
Blade is finally wilting, also have side blade first wilt or whole strain blade at the same wilt, early stage, diseased plant daytime wilt, be close to
Evening restores, and sick leaf shoals.After the onset, antecedent soil moisture, temperature is higher, 2~3 days complete stools, that is, wilting.If temperature is lower, cloudy weather for several days running or
It is withered after diseased plant sustainable 1 week when soil moisture content is higher, but blade still keeps green or slightly weaker, therefore claim bacterial wilt.
Bacterial soft rot of potato (Erwinia carotovora subsp.carotovora), it is independent by several Erwinias
Or mixed infection, a kind of bacteriosis for storage period potato tubers of causing harm.Be found everywhere through the world potato producing region, annual difference journey
The generation of degree is one of the Major Diseases of country, Europe, the United States potato.General time underproduction 3%-5%, often with the compound sense of dry rot
Dye, causes greater loss.Soft rot typically occurs on the stem tuber before Later growth harvests and on the stem tuber of storage.It is infected
Stem tuber, stomata slight depression, brown or brown are around in water soaking mode.In dry conditions, scab is hardened, dries out, and downright bad group
Knit recess.When developing to rotten, soft rotten tissue is in wet cream color or sepia, there is soft granular substance thereon.Infected group
Knit obvious with health tissues boundary, there is the pigment of brown or black at scab edge.Rot early stage odorlessness, has after Secondary Infection smelly
Gas, mucus, viscous substance.
Mango bacterial angular leaf spot (Xanthomonascampestrispv.mangiferaeindicae), also known as bacterium
Property black spot or burst swing disease.Main the cause harm tip, leaf and fruit.Do not turn green shoot blade of catching an illness and shows pinhead-sized pore, after
It is extended to the small blackspot of protrusion, surrounding has Huang to swoon, and scab is in polygonal, and later period scab is fused into irregular big blackspot, leaf middle arteries
Petiole gives birth to lobe streak.Fruit is caught an illness just raw syringe needle shape black dot on pericarp, after be extended to crateriform dark brown ulceration,
Easily induce anthrax-bacilus, the intrusion of base of a fruit corruption bacterium.The mango producing region such as Guangdong, Guangxi, Hainan, Fujian occurs universal.
Bacterial blight of rice (Xanthomonasoryzae), one of rice disease, diseased plant blade tip and edge are come into being yellow green
Spot, after along vein develop sickly, the long streak of yellowish-brown, last graying white and it is withered.Primary source of infection is mainly disease grass
With sick paddy, bacterium travels to rice seedling bed through water flow, and rice shoot is caused to be fallen ill.Symptom is not often showed after early-rice seedlings infection, becomes band
Vaccine.Late rice just can express symptom in three four leaf stages.Nursery period waterflooding, seeding stage waterflooding, the infected chance of rice shoot increase, flood
The drowned number of water is more, and the time is longer, and rice shoot bacterial bearing rate is higher.After the shoot transplanting equipment with vaccine or aobvious symptom is to crop field, arrive
Start to fall ill when late tillering state rice strain premunition drop, becomes primary infection focus.A large amount of bacterial ooze is generated in the sick portion of diseased plant again later,
It is propagated by means of pouring water with storm, is constantly infected again, disease is made constantly to expand in field.
Citrus bacterial canker disease (Xanthomonas campestris pv), pathogenetic bacteria are overwintering in citrus disease portion tissue.It is next
When year proper temperature, humidity are high, bacterium is overflowed from scab, makees short distance propagation by means of wind, rain, insect and branches and leaves brought into interactive contact.
It propagates at a distance and then mainly passes through the nursery stock that carries disease germs, scion and fruit.Germ falls on the tender tissue of host, by stomata, water
Hole, hole skin and wound intrusion.The disease resistance significant difference of different Citrus Cultivars, wherein sweet orange class is seriously susceptible, bitter orange, shaddock, trifoliate orange
Take second place with citrange, the wide more resistance to disease of skin citrus, and golden mandarin orange is then disease-resistant.The tender tip leaf and newly formed young fruit of hair, stomata are just taken out
It has not yet been formed, germ cannot invade.Be critically ill harmful Citrus leaf, branch and the fruit.Nursery stock and the aggrieved especially severe of treelet can be made
At fallen leaves, spike top, tree vigo(u)r is influenced；The aggrieved severe one shedding of fruit, less serious case with ill scar, do not rot, substantially reduce by storage tolerance, generation
Fruit commodity value, increases orchard worker by insect pest preventing and controlling cost, and economic benefit is impaired.
Canker of pear (Erwinia amylovora) also known as fire blight of pear, most typical symptom are flower, fruit and blade
After by the infringement of fire blast bacterium, blackening brown is withered quickly, like burning, but still hangs on the tree and does not fall, so gaining the name.Pears fire
Epidemic disease is the destructive disease on European pear tree, is occurred in Japan, Korea various regions also more.China not yet finds this disease, belongs to dangerous
Venereal disease evil is the important quarantine object in China.In wilting shape, dark brown after floral organ is killed, and anthocaulus is spread to downwards, make anthocaulus
In water stain shape.Blade morbidity, first turns black since leaf margin, then develops along vein, final full leaf blackening, wilting.At the beginning of disease fruit
Unboiled water stain shape spot, rear dimmed brown, and have yellow mucus spilling, last disease fruit blackening and drying shrinkage.Limb is killed, just in water stain
Shape has limbus, and it is brown to black that ulcer shape occurs in rear disease portion recess.
Prospect on Kiwifruit Bacterial Canker (Pseudomonas syringae pv.actinidae), it is raw that one kind seriously threatening Kiwi berry
The crushing bacterial disease of production, is listed in Forest Plant Quarantine object.This disease breaks with tremendous force, and the popular time causes full garden
It is on the brink of to destroy, causes heavy economic losses, the occurrence injury of the disease not only lowers yield, but also pericarp is caused to thicken, and fruity becomes
Acid, fruit become smaller, and fruit shape is different, quality decline, and commodity value reduces.Disease shows as yellowish-brown or rust red, and germ can
Infecting to xylem causes topical ulcers to rot, and influences the conveying and absorption of nutrient, causes tree vigo(u)r weak, stem can be surround when serious
Bar causes tree body dead.Young sprout, branches and tendrils, blade and the bud of main harm Kiwi berry, to endanger based on the raw branch of 1-2, one
As do not endanger root and fruit.After plant is aggrieved, start to fall ill in mid or late Febuary, the longitudinal crevasse of 1-3cm long occur on branches and tendrils,
And the water stain shape mucus of bottle green is flowed out, under super-humid conditions, in crack, white bacterial ooze is secreted in punishment, and last gummosis site tissue, which sink, to be become
Black is in iron rust shape ulceration, and sick portion upper end branch is cracked, and atrophy is withered.Occurs 1-3mm irregular shape after blade is aggrieved
Crineous scab, scab outer rim 2-5mm range turn yellow, and grave illness leaf inward curl is dried-up, easy to fall off, after bud is aggrieved, is blooming
Preceding browning is withered, and floral organ is aggrieved, and corolla browning is in water corruption shape.
In recent years, generation of the bacillary and fungal disease on crops is in apparent ascendant trend, and disease control is difficult
Degree increasingly comes greatly, and being forbidden to use for antibiotic is put forward new requirements to the selection of disease control medicament, it would be highly desirable to green is needed,
Safety, efficient pesticide control.
The difficulty of prevention and cure of disease is increasing at present, the change of pattern of farming, the rising of pathogen resistance, the prevention and treatment of single dose
Effect is not so good as people's will, and the prevention and treatment of plant disease is faced with huge challenge.
Summary of the invention
It is an object of the invention to: provide a kind of control efficiency the Synergistic sterilizing group outstanding containing benziothiazolinone and oxolinic acid
Close object.Inventor shows good inhibiting effect to plurality of plant diseases by largely raw experiment discovery oxolinic acid of surveying.This hair
Bright composition is with compound screening experiment discovery is crossed, and composition is to cucumber bacterial angular leaf spot, bacterial wilt of tomato, potato
Soft rot, mango bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, canker of pear and Prospect on Kiwifruit Bacterial Canker have significantly
Effect performs clearly better than the effect of single dose, while can reduce Pesticide use amount.The invention adopts the following technical scheme:
A kind of bactericidal composition containing benziothiazolinone and oxolinic acid, it is characterised in that: the activity that the composition contains
Ingredient is that benziothiazolinone and oxolinic acid, wherein benziothiazolinone and the weight ratio of oxolinic acid are 60-1:1-60.
The preferred weight ratio of the benziothiazolinone and oxolinic acid is 40:1-1:40.
The bactericidal composition using benziothiazolinone and oxolinic acid as principle active component, can with insecticides adjuvant, filler or
Solvent is configured to any one dosage form allowed on pesticide.
The benziothiazolinone and the preferred suspending agent of the dosage form of oxolinic acid, wettable powder, water dispersible granules, granule, water and milk
Agent, microemulsion or ultra low volume liquids.
The weight percent of the benziothiazolinone and the quality summation of oxolinic acid in above-mentioned dosage form is 2-60%.
The present invention also provides the bactericidal compositions in prevention and treatment cucumber bacterial angular leaf spot, bacterial wilt of tomato, potato
It is applied on soft rot, mango bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, canker of pear and Prospect on Kiwifruit Bacterial Canker,
The present invention has found through a large number of experiments, and when preventing and treating these diseases, bactericidal composition of the present invention has apparent synergistic
Effect, and dosage is few, the lasting period is long, is not easy to produce resistance, and is the outstanding medicament of nuisanceless fruits and vegetables production.
The dosage of the composition is 20-80g a.i./hm2。
Specific embodiment
Technical solution of the present invention and technical effect are described further below with reference to specific embodiment.
Percentage of the present invention is weight percentage, but embodiments of the present invention are not limited to the embodiment statement
Range.
The method that this experiment is combined using indoor toxicity test and field trial.Indoor toxicity test is first passed through, is screened
Appropriate proportioning on this basis, then carries out field trial.
The indoor toxicity test that 1 benziothiazolinone of embodiment is compounded with oxolinic acid
Indoor inhibitory effect measuring method: using Nephelometric Determination bactericidal composition to the inhibiting effect of germ.Test is abided by
According to national sector standard " the 16th part of NYT1156.16-2006 farm-chemical indoor determination test rule fungicide: inhibition bacterium
Increment tests turbidity method ", it is diluted to the medicament mother liquor of various concentration, after mixing fullys shake, by the medicament of different volumes
Mother liquor is added in the 250ml specification triangular flask equipped with 50ml NB culture medium, is made into the pastille culture medium of various concentration, and control adds
Same volume sterile water mixes well rear spare.Cultured germ is diluted to 100NTU.Every bottle of pastille culture medium is inoculated with 50 μ L
Seed liquor surveys the muddy angle value of each bottle after 30 DEG C of 200rpm cultures for 24 hours respectively.The data input Excel table measured, is adopted
The medicament is calculated at various concentrations to the growth inhibition ratio of germ with following formula.
According to growth inhibition ratio, the virulence of corresponding medicament is found out using DPS data software bioassay profession statistical function
Regression equation and median effective concentration EC50, then according to Sun Yunpei's Method [Sun Yun pei, Johnson E R.Analysis of
Joint Action of Insecticides against House Flies[J].Journal of
EconomicEntomology, 1960,53 (5): 887-892] calculate co-toxicity coefficient (CTC).
When CTC≤80, then composition shows as antagonism, and when 80 < CTC < 120, then composition shows as summation action,
When CTC >=120, then composition shows as synergistic effect.
Survey toxicity index (ATI)=(standard agent EC50/ for reagent effect EC50)×100；
The toxicity index of the percentage composition+B medicament of A in toxicity index × mixture of theoretical virulence coefficient (TTI)=A medicament
The percentage composition of B in × mixture；
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] × 100.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 1 to cucumber bacterial angular leaf spot The Toxicity Determination result.
1 benziothiazolinone of table compounds the indoor toxicity test to cucumber bacterial angular leaf spot with oxolinic acid different proportion
As shown in Table 1, benziothiazolinone, oxolinic acid are to the EC of cucumber bacterial angular leaf spot50Respectively 1.21mg/L and 1.97mg/
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120, shows good synergy for L, benziothiazolinone and oxolinic acid mixed ratio
Effect.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 2 to bacterial wilt of tomato The Toxicity Determination result.
2 benziothiazolinone of table compounds the indoor toxicity test to bacterial wilt of tomato with oxolinic acid different proportion
As shown in Table 2, benziothiazolinone, oxolinic acid are to the EC of bacterial wilt of tomato50Respectively 1.43mg/L and 2.17mg/L, thiophene are mould
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120, shows good synergistic effect for ketone and oxolinic acid mixed ratio.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 3 to bacterial soft rot of potato The Toxicity Determination result.
3 benziothiazolinone of table compounds the indoor toxicity test to bacterial soft rot of potato with oxolinic acid different proportion
As shown in Table 3, benziothiazolinone, oxolinic acid are to the EC of bacterial soft rot of potato50Respectively 1.74mg/L and 2.47mg/L, thiophene
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120 for mould ketone and oxolinic acid mixed ratio, shows good synergy and makees
With.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 4 to mango bacterial angular leaf spot The Toxicity Determination result.
4 benziothiazolinone of table compounds the indoor toxicity test to mango bacterial angular leaf spot with oxolinic acid different proportion
As shown in Table 4, benziothiazolinone, oxolinic acid are to the EC of mango bacterial angular leaf spot50Respectively 1.34mg/L and 1.97mg/
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120, shows good synergy for L, benziothiazolinone and oxolinic acid mixed ratio
Effect.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 5 to bacterial blight of rice The Toxicity Determination result.
5 benziothiazolinone of table compounds the indoor toxicity test of bacterial blight of rice with oxolinic acid different proportion
As shown in Table 5, benziothiazolinone, oxolinic acid are to the EC of bacterial blight of rice50Respectively 1.63mg/L and 2.27mg/L, thiophene
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120 for mould ketone and oxolinic acid mixed ratio, shows good synergy and makees
With.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 6 to citrus bacterial canker disease The Toxicity Determination result.
6 benziothiazolinone of table compounds the indoor toxicity test to citrus bacterial canker disease with oxolinic acid different proportion
As shown in Table 6, benziothiazolinone, oxolinic acid are to the EC of citrus bacterial canker disease50Respectively 1.32mg/L and 1.91mg/L, thiophene are mould
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120, shows good synergistic effect for ketone and oxolinic acid mixed ratio.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 7 to canker of pear The Toxicity Determination result.
7 benziothiazolinone of table compounds the indoor toxicity test to canker of pear with oxolinic acid different proportion
As shown in Table 7, benziothiazolinone, oxolinic acid are to the EC of canker of pear50Respectively 1.56mg/L and 1.73mg/L, benziothiazolinone
With oxolinic acid mixed ratio in 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120, shows good synergistic effect.
Benziothiazolinone and oxolinic acid bactericidal composition are shown in Table 8 to Prospect on Kiwifruit Bacterial Canker The Toxicity Determination result.
8 benziothiazolinone of table compounds the indoor toxicity test to Prospect on Kiwifruit Bacterial Canker with oxolinic acid different proportion
As shown in Table 8, benziothiazolinone, oxolinic acid are to the EC of Prospect on Kiwifruit Bacterial Canker50Respectively 1.39mg/L and 1.85mg/L, thiophene
In 60-1:1-60, co-toxicity coefficient (CTC) is all larger than 120 for mould ketone and oxolinic acid mixed ratio, shows good synergy and makees
With.
Above the experimental results showed that, the composition pesticide that benziothiazolinone is compounded with oxolinic acid 60-1:1-60 is to cucumber bacterium
Property angular leaf spot, bacterial wilt of tomato, bacterial soft rot of potato, mango bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, pears
The prevention and treatment of branch-rot and Prospect on Kiwifruit Bacterial Canker has good synergistic function, illustrates below with reference to example of formulations with benziothiazolinone
With pesticidal preparations that oxolinic acid is effective component preparation to the field efficacy experimental conditions of four kinds of above-mentioned germs.
The pesticidal preparations embodiment of preparation is as follows:
One: 21% benziothiazolinone oxolinic acid suspending agent of example of formulations
Benziothiazolinone 20%, oxolinic acid 1%, lignosulfonates 2%, fatty alcohol polyoxyethylene ether 3%, ethylene glycol 5%, silicon
Sour magnalium 1%, xanthan gum 0.15%, organic silicon defoamer 0.4%, water supplies 100%.
Two: 21% benziothiazolinone oxolinic acid suspending agent of example of formulations
Benziothiazolinone 1%, oxolinic acid 20%, alkylbenzene sulfonate 2%, nonylphenol polyoxyethylene ether 4.5%, urea 5%, silicon
Sour magnalium 0.4%, xanthan gum 0.2%, organic silicon defoamer 0.5%, water supplies 100%.
Three: 6% benziothiazolinone oxolinic acid wettable powder of example of formulations
Benziothiazolinone 1%, oxolinic acid 5%, naphthalene sulfonate 5%, styrylphenol polyoxyethylene ether phosphate 3%, 12
Sodium alkyl sulfate 2%, white carbon black 4%, kaolin supplies 100%.
Four: 12% benziothiazolinone oxolinic acid wettable powder of example of formulations
Benziothiazolinone 10%, oxolinic acid 2%, naphthalene sulfonate 4%, phenethyl phenol polyoxyethylene poly-oxygen propylene aether 4%, dodecane
Base sodium sulphate 3%, white carbon black 2%, diatomite supplies 100%.
Five: 12% benziothiazolinone oxolinic acid water dispersible granules of example of formulations
Benziothiazolinone 2%, oxolinic acid 10%, lignosulfonates 3%, alkyl polyoxyethylene sulfate salt 3%, white carbon black 3%,
Sodium sulphate 10%, polyvinyl alcohol 0.1%, kaolin supplies 100%.
Six: 6% benziothiazolinone oxolinic acid water dispersible granules of example of formulations
Benziothiazolinone 5%, oxolinic acid 1%, cyclohexanone formaldehyde condensation products 3%, polycarboxylate 5%, lauryl sodium sulfate
4%, white carbon black 3%, ammonium sulfate 10%, starch 4%, diatomite supplies 100%.
Seven: 6% benziothiazolinone oxolinic acid granule of example of formulations
Benziothiazolinone 3%, oxolinic acid 3%, polycarboxylate 2%, calcium lignosulfonate 4%, polyvinyl alcohol 3.5%, polyester tree
Rouge 0.5%, Arabic gum 2%, brick slag are mended to 100%.
Eight: 8% benziothiazolinone oxolinic acid granule of example of formulations
Benziothiazolinone 4%, oxolinic acid 4%, dioctyl sodium sulfosuccinate 1.5%, sodium butylnaphthalenesulfonate 4%, carboxymethyl are fine
Dimension element 4%, butadiene resin film forming agent 0.3%, polyvinyl alcohol 3%, quartz sand are mended to 100%.
Nine: 10% benziothiazolinone oxolinic acid aqueous emulsion of example of formulations
Benziothiazolinone 5%, oxolinic acid 5%, dimethyldecamide 8%, dimethylbenzene 5%, phenethyl phenol polyoxyethylene polyoxy third
Alkene ether 4%, fatty alcohol polyoxyethylene ether formaldehyde condensation products sulfate 2.5%, urea 5%, water supplies 100%.
Ten: 12% benziothiazolinone oxolinic acid aqueous emulsion of example of formulations
Benziothiazolinone 6%, oxolinic acid 6%, dimethyldecamide 10%, cyclohexanone 5%, fatty alcohol polyoxyethylene ether 3.5%,
Fatty alcohol polyoxyethylene ether formaldehyde condensation products sulfate 4%, ethylene glycol 4%, water supplies 100%.
11: 24% benziothiazolinone oxolinic acid microemulsion of example of formulations
Benziothiazolinone 20%, oxolinic acid 4%, cyclohexanone 10%, dimethyldecamide 10%, fatty alcohol polyoxyethylene ether 3, rouge
Fat alcohol polyoxyethylene ether formaldehyde condensation products sulfate 5%, calcium dodecyl benzene sulfonate 4%, water supplies 100%.
12: 24% benziothiazolinone oxolinic acid microemulsion of example of formulations
Benziothiazolinone 4%, oxolinic acid 20%, dimethylbenzene 20%, cyclohexanone 5%, fatty alcohol polyoxyethylene ether 3%, fatty alcohol
Polyoxyethylene ether formaldehyde condensation products sulfate 5%, calcium dodecyl benzene sulfonate 5%, water supplies 100%.
13: 22% benziothiazolinone oxolinic acid ultra low volume liquids of example of formulations
Benziothiazolinone 2%, oxolinic acid 20%, dimethyldecamide 15%, fatty alcohol polyoxyethylene ether 4%, detergent alkylate
Sulfoacid calcium 5%, solvent naphtha supplies 100%.
14: 23% benziothiazolinone oxolinic acid ultra low volume liquids of example of formulations
Benziothiazolinone 3%, oxolinic acid 20%, dimethyldecamide 15%, fatty alcohol polyoxyethylene ether formaldehyde condensation products sulfuric acid
Salt 4%, calcium dodecyl benzene sulfonate 5%, solvent naphtha supplies 100%.
By above-mentioned pesticidal preparations embodiment to cucumber bacterial angular leaf spot, bacterial wilt of tomato, bacterial soft rot of potato, mango
Bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, canker of pear and Prospect on Kiwifruit Bacterial Canker carry out field control effectiveness test.
Embodiment 2 prevents and treats the experiment of cucumber bacterial angular leaf spot field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: Experimental Area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in April, 2018 in the Shijiazhuang City of Hebei Province town Pingshan County Gu Yue, by effective component per acre
2g, 3g and 4g are watered carry out even spraying, are administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 9 after medicine:
9 benziothiazolinone of table is compounded with oxolinic acid different proportion to cucumber bacterial angular leaf spot pharmacodynamic test
As can be seen from Table 9, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to the bacillary angle spot of cucumber
The control efficiency of disease is better than comparison medicament control efficiency, and composition shows excellent collaboration in the case where being lower than single dose dosage
Building performance, the lasting period is long.
The experiment of 3 control of plant bacterial wilt field efficacy of embodiment
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in April, 2018 in Hebei province, Anxin County, the Baoding town Shi Fo, by effective component 2g per acre,
3g and 4g is watered carry out even spraying, is administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 10 after medicine:
10 benziothiazolinone of table is compounded with oxolinic acid different proportion to bacterial wilt of tomato pharmacodynamic test
As can be seen from Table 10, benziothiazolinone and oxolinic acid Bactericidal composite prevent bacterial wilt of tomato under relatively low dosage
Effect is controlled better than comparison medicament control efficiency, composition shows excellent synergy in the case where being lower than single dose dosage
Property, lasting period are long.
Embodiment 4 prevents and treats the experiment of bacterial soft rot of potato field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in April, 2018 in Hebei province Zhangjiakou City Huaian County, by effective component 2g, 3g per acre and
4g is watered carry out even spraying, is administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 11 after medicine:
11 benziothiazolinone of table is compounded with oxolinic acid different proportion to bacterial soft rot of potato pharmacodynamic test
As can be seen from Table 11, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to bacterial soft rot of potato
Control efficiency is better than comparison medicament control efficiency, and composition shows excellent synergy in the case where being lower than single dose dosage
Property, lasting period are long.
The experiment of 5 biocontrol of mango bacterial angular leaf spot field efficacy of embodiment
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in in September, 2018 in the Compounds in Dongfang City of Hainan Province town Ba Suo, by effective component 2g, 3g per acre and
4g is watered carry out even spraying, is administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 12 after medicine:
12 benziothiazolinone of table is compounded with oxolinic acid different proportion to mango bacterial angular leaf spot pharmacodynamic test
As can be seen from Table 12, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to the bacillary angle spot of mango
The control efficiency of disease is better than comparison medicament control efficiency, and composition shows excellent collaboration in the case where being lower than single dose dosage
Building performance, the lasting period is long.
Embodiment 6 prevents and treats the experiment of bacterial blight of rice field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in June, 2018 in Ningbo City, Zhejiang Province Xiangshan County town great Xu, by effective component per acre
2g, 3g and 4g are watered carry out even spraying, are administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 13 after medicine:
13 benziothiazolinone of table is compounded with oxolinic acid different proportion to bacterial blight of rice pharmacodynamic test
As can be seen from Table 13, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to bacterial blight of rice
Control efficiency is better than comparison medicament control efficiency, and composition shows excellent synergy in the case where being lower than single dose dosage
Property, lasting period are long.
Embodiment 7 prevents and treats the experiment of citrus bacterial canker disease field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is in in September, 2018, in Guangxi province Bose City Lingyun County, township, the Yao nationality is carried out inwardly, by effective per acre
Ingredient 2g, 3g and 4g are watered carry out even spraying, are administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table after medicine
14:
14 benziothiazolinone of table is compounded with oxolinic acid different proportion to citrus bacterial canker disease pharmacodynamic test
As can be seen from Table 14, benziothiazolinone and oxolinic acid Bactericidal composite prevent citrus bacterial canker disease under relatively low dosage
Effect is controlled better than comparison medicament control efficiency, composition shows excellent synergy in the case where being lower than single dose dosage
Property, lasting period are long.
Embodiment 8 prevents and treats the experiment of canker of pear field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is in autonomous in Xinjiang Uygur Autonomous Regions's Bayangolmongol in August, 2018 in August, 2018
State township, Korla City Awat County carries out, and is watered carry out even spraying by effective component 2g, 3g and 4g per acre, is administered 1 time altogether, after medicine
The prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 15:
15 benziothiazolinone of table is compounded with oxolinic acid different proportion to canker of pear pharmacodynamic test
As can be seen from Table 14, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to the prevention and treatment of canker of pear
Effect is better than comparison medicament control efficiency, and composition shows excellent synergetic in the case where being lower than single dose dosage,
Lasting period is long.
Embodiment 9 prevents and treats the experiment of Prospect on Kiwifruit Bacterial Canker field efficacy
1. experiment process: this experiment sets three concentration for the treatment of according to the difference of ingredient respectively, and comparison medicament is pesticide respectively
20% oxolinic acid suspending agent of single dose and the control of 5% benziothiazolinone suspending agent and blank clear water.
2. test method: test area is each cell 66.7m2, it is repeated 3 times；Preventive effect after investigating and be administered before application
Investigation method are as follows: 5 points of grab sample in experiment process area carry out severity Scaling, meter according to national field trial relevant criterion
Calculate preventive effect.
Present invention experiment is carried out in in August, 2018 in Xi'an City, Shanxi Province Zhouzhi County Jixian county town, by effective component per acre
2g, 3g and 4g are watered carry out even spraying, are administered 1 time altogether, the prevention and treatment checked in 7 days, 14 days and 21 days the results are shown in Table 16 after medicine:
16 benziothiazolinone of table is compounded with oxolinic acid different proportion to Prospect on Kiwifruit Bacterial Canker pharmacodynamic test
As can be seen from Table 16, benziothiazolinone and oxolinic acid Bactericidal composite are under relatively low dosage to Prospect on Kiwifruit Bacterial Canker
Control efficiency is better than comparison medicament control efficiency, and composition shows excellent synergy in the case where being lower than single dose dosage
Property, lasting period are long.
From above 9 raw survey embodiments it is found that benziothiazolinone and oxolinic acid are compounded according to mass ratio for 60-1:1-60,
It can be made into suspending agent, wettable powder, water dispersible granules, granule, aqueous emulsion, microemulsion or ultra low volume liquids, to cucumber
Bacterial angular leaf spot, bacterial wilt of tomato, bacterial soft rot of potato, mango bacterial angular leaf spot, bacterial blight of rice, c itrus canker
Disease, canker of pear and Prospect on Kiwifruit Bacterial Canker have significant control efficiency, and synergistic effect is obvious, reduces pesticide usage amount and life
Cost is produced, to crop safety, the lasting period is long, and it is laborsaving time saving, the service efficiency of pesticide is improved, is the ideal for preventing and treating such disease
Medicament has wide practical use in production.
In conclusion composition of the invention is the compound scheme using two kinds of effective component of benziothiazolinone and oxolinic acid,
Bactericidal activity is not the active superposition of simple two kinds of effective component, compared with the preparation of existing single active ingredient, except having
Outside apparent bactericidal effect, and there is significant synergistic effect, control cost reduces, and to crop safety, the lasting period is long, meets agriculture
The security requirement of medicine preparation.
Bactericidal composition containing benziothiazolinone and oxolinic acid of the invention is described by specific example, this
Field technical staff can use for reference the content of present invention, and the links such as appropriate feed change, process conditions realize corresponding other purposes,
Its correlation changes all without departing from the contents of the present invention, and all similar substitutions and modifications are to those skilled in the art
It will be apparent that being considered as being included within the scope of the present invention.
Claims (7)
1. a kind of bactericidal composition containing benziothiazolinone and oxolinic acid, it is characterised in that: the composition contain activity at
It is divided into benziothiazolinone and oxolinic acid, wherein benziothiazolinone and the weight ratio of oxolinic acid are 60-1:1-60.
2. bactericidal composition according to claim 1, it is characterised in that: the preferred weight ratio of the benziothiazolinone and oxolinic acid
For 40:1-1:40.
3. bactericidal composition according to claim 1 or 2, it is characterised in that: with benziothiazolinone and oxolinic acid be it is main effectively
Ingredient and insecticides adjuvant, filler or solvent are configured to any one dosage form allowed on pesticide.
4. bactericidal composition according to claim 1,2 or 3, it is characterised in that: the preferred suspending agent of its dosage form, wettable
Pulvis, water dispersible granules, granule, aqueous emulsion, microemulsion or ultra low volume liquids.
5. bactericidal composition according to claim 4, it is characterised in that: benziothiazolinone and the gross mass of oxolinic acid are at above-mentioned dose
Weight percent in type is 2-60%.
6. -5 any bactericidal compositions are in prevention and treatment cucumber bacterial angular leaf spot, bacterial wilt of tomato, horse according to claim 1
On bell potato soft rot, mango bacterial angular leaf spot, bacterial blight of rice, citrus bacterial canker disease, canker of pear and Prospect on Kiwifruit Bacterial Canker
Application.
7. bactericidal composition described in -6 according to claim 1, it is characterised in that: the dosage of the composition is 20-80g
a.i./hm2。
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112075438A (en) * | 2020-09-01 | 2020-12-15 | 陕西西大华特科技实业有限公司 | Bactericidal composition containing benziothiazolinone and shenqinmycin and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010173972A (en) * | 2009-01-29 | 2010-08-12 | Japan Enviro Chemicals Ltd | Antimicrobial composition for industrial use |
| CN101990398A (en) * | 2008-04-07 | 2011-03-23 | 拜耳作物科学有限公司 | Stable aqueous spore-containing formulation |
| CN105961413A (en) * | 2016-06-21 | 2016-09-28 | 广东中迅农科股份有限公司 | Bactericidal composition containing oxolinic acid and bromothalonil |
| CN106376578A (en) * | 2016-08-31 | 2017-02-08 | 江苏辉丰农化股份有限公司 | Bactericide composition |
| CN106417325A (en) * | 2016-08-31 | 2017-02-22 | 陕西西大华特科技实业有限公司 | Bactericidal composition containing benziothiazolinone and copper quinolate |
-
2019
- 2019-04-17 CN CN201910307324.2A patent/CN109938033A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101990398A (en) * | 2008-04-07 | 2011-03-23 | 拜耳作物科学有限公司 | Stable aqueous spore-containing formulation |
| JP2010173972A (en) * | 2009-01-29 | 2010-08-12 | Japan Enviro Chemicals Ltd | Antimicrobial composition for industrial use |
| CN105961413A (en) * | 2016-06-21 | 2016-09-28 | 广东中迅农科股份有限公司 | Bactericidal composition containing oxolinic acid and bromothalonil |
| CN106376578A (en) * | 2016-08-31 | 2017-02-08 | 江苏辉丰农化股份有限公司 | Bactericide composition |
| CN106417325A (en) * | 2016-08-31 | 2017-02-22 | 陕西西大华特科技实业有限公司 | Bactericidal composition containing benziothiazolinone and copper quinolate |
Non-Patent Citations (1)
| Title |
|---|
| 余露: "高效广谱杀菌剂噻霉酮", 《农药市场信息》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112075438A (en) * | 2020-09-01 | 2020-12-15 | 陕西西大华特科技实业有限公司 | Bactericidal composition containing benziothiazolinone and shenqinmycin and application thereof |
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