CN109892247B - Experimental device for detect rat cognitive function of cat participation - Google Patents
Experimental device for detect rat cognitive function of cat participation Download PDFInfo
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- CN109892247B CN109892247B CN201910318761.4A CN201910318761A CN109892247B CN 109892247 B CN109892247 B CN 109892247B CN 201910318761 A CN201910318761 A CN 201910318761A CN 109892247 B CN109892247 B CN 109892247B
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention provides an experimental device for detecting cognitive functions of rats, which comprises an outer ring plate, an inner ring plate, a switch door, a rotating device, a lifting device and a lashing rope, wherein the outer ring plate is connected with the inner ring plate; the outer ring plate is arranged on the base plate, the inner ring plate is arranged on the base plate in the outer ring plate, an annular area enclosed between the inner ring plate and the outer ring plate is a safety area, the area in the inner ring plate is a danger area, a plurality of escape openings are uniformly formed in the inner ring plate, switch doors which are opened to the safety area are respectively arranged at the escape openings, and the corresponding escape openings are closed when the switch doors are closed; the lifting device is arranged on the base plate in the center of the dangerous area, and the rotating device is arranged on the lifting device and can freely rotate on the horizontal plane; one end of the sleeve rope is connected to the rotating device, and the other end of the sleeve rope is used for sleeving cats participating in the experiment. The experimental device has the advantages of simple structure, convenient use and visual effect, and can comprehensively and objectively reflect the cognitive function of the rat.
Description
Technical Field
The invention relates to the field of animal experiments, in particular to an experimental device for detecting cognitive functions of rats with participation of cats.
Background
In the research fields of brain cognitive function, neural network plasticity, drug evaluation, genetic engineering and the like, the influence of different factors on the brain cognitive function is often observed and evaluated through a rat visual cognitive behavior experiment, namely, through training, a rat and a mouse are led to learn to finish specific behaviors according to visual cues, so that the brain cognitive function is evaluated according to the behavior feedback result. Training is a key step of a learning process of the visual cognitive behaviors of the mice, and aims to establish conditional reflection between specific visual clues and specific behavior responses so as to complete visual cognitive tasks such as visual target identification, visual working memory and the like.
At present, an experimental device for detecting the cognitive function (behavior) of a rat by using animals as stimulus sources is not known, the existing devices such as a water maze, an electric maze and the like can only detect a certain aspect of the cognitive function, the passing path in the device is fixed, the movement of the rat has certain regularity, the cognitive function state of the rat cannot be well reflected under the emergency condition of the animal stimulus sources, the instinct reaction of the rat and the cat forced escape is combined, and the escape reaction of the rat is not regular because of the irregular movement of the cat, so that the cognitive function such as the learning and the memory of the rat can be comprehensively, objectively and effectively detected.
Disclosure of Invention
The invention provides an experimental device for detecting cognitive functions of rats with participation of cats, which is used for solving the problems of high repeatability, incomplete and objective detection of cognitive behaviors of rats in the prior art.
The technical characteristics used for realizing the invention are as follows:
an experimental device for detecting cognitive functions of rats with cat participation comprises an outer ring plate, an inner ring plate, a switch door, a rotating device, a lifting device and a sleeve rope;
the outer ring plate is arranged on the base plate, the inner ring plate is arranged on the base plate in the outer ring plate, an annular area enclosed between the inner ring plate and the outer ring plate is a safety area, the area in the inner ring plate is a danger area, a plurality of escape openings are uniformly formed in the inner ring plate, switch doors which are opened to the safety area are respectively arranged at the escape openings, and the corresponding escape openings are closed when the switch doors are closed;
the lifting device is arranged on the base plate in the center of the dangerous area, and the rotating device is arranged on the lifting device and can freely rotate on the horizontal plane;
one end of the sleeve rope is connected to the rotating device, and the other end of the sleeve rope is used for sleeving cats participating in the experiment.
Further, the outer ring plate and the inner ring plate are consistent in shape.
Further, the outer ring plate and the inner ring plate are both circular.
Further, the outer ring plate and the inner ring plate are both regular polygons.
Further, the outer ring plate and the inner ring plate are regular hexagons or regular octagons.
Further, the escape openings are arranged at the bottoms of the side plate bodies of the inner ring plate.
Further, the opening and closing door is a side-by-side door or a side-by-side door.
The beneficial effects are that:
the experimental device simplifies the judgment of the cognition of rats by arranging the isolated safety area, the dangerous area and the escape opening for communicating the safety area and the dangerous area; through setting up noose, rotary device, elevating gear, not only make the cat well participate in the experiment, guaranteed the safety of participating in the experiment rat moreover. The experimental device has the advantages of simple structure, convenient use and visual effect, and can comprehensively and objectively reflect the cognitive function of the rat.
Drawings
The invention will be further described with reference to the accompanying drawings and specific examples, in which:
fig. 1 is a structural view of a first embodiment;
FIG. 2 is a cross-sectional view taken along A-A of FIG. 1;
fig. 3 is a structural diagram of a second embodiment;
fig. 4 is a structural diagram of the third embodiment.
Reference numerals in the drawings: 1. outer coaming, 2, safety area, 3, inner annular plate, 31, escape opening, 4, danger area, 5, rotary device, 6, lashing wire, 7, lifting device, 8, switch door, 9, base plate, 10, buckle.
Detailed Description
The conception, specific structure, and technical effects produced by the present invention will be clearly and completely described below with reference to the embodiments and the drawings to fully understand the objects, features, and effects of the present invention. It is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments, and that other embodiments obtained by those skilled in the art without inventive effort are within the scope of the present invention based on the embodiments of the present invention.
As shown in fig. 1, 2, 3 and 4, an experimental device for detecting cognitive functions of rats, which is participated by cats, comprises an outer ring plate 1, an inner ring plate 3, a switch door 8, a rotating device 5 capable of rotating horizontally and freely, a lifting device 7 capable of lifting up and down, and a sleeve rope 6.
The outer ring plate 1 is arranged on the base plate 9, the inner ring plate 3 is arranged on the base plate 9 in the outer ring plate 1, the area in the inner ring plate 3 is a dangerous area 4, and the annular area enclosed between the inner ring plate 3 and the outer ring plate 1 is a safe area 2; a plurality of identical escape openings 31 are uniformly formed in the bottom of the inner annular plate 3, each escape opening 31 communicates the safety area 2 and the danger area 4 with each other, and the size of each escape opening 31 is set so that a rat can pass through but a cat participating in an experiment cannot pass through.
The switch doors 8 are respectively arranged at the escape openings 31, the switch doors 8 are identical, a rat memorable reference object is avoided, the corresponding escape openings 31 are closed when the switch doors 8 are closed, and the corresponding escape openings 31 are opened towards the safety zone 2 by the switch doors 8; preferably, the switch door 8 is a side-by-side door or a side-by-side door, in this embodiment, the switch door 8 is a side-by-side door in a vertical direction, each switch door 8 is hinged on the inner ring plate 3 at the top end of each escape opening 31, buckles 10 for locking the corresponding switch door 8 are respectively arranged around the escape openings 31, the buckles 10 are connected with a driving device, the driving device drives the corresponding buckles 10 to open and close, and under the condition that a certain switch door 8 is not locked, a rat in the danger zone 4 can crash the switch door 8 and enter the safety zone 2 through the escape openings 31, and the switch door 8 is automatically closed under the action of gravity after the rat passes through the escape openings 31; under the condition that the switch door 8 is locked by the buckle 10, the rat in the danger area 4 cannot crash the corresponding switch door 8, and the switch door 8 can be locked by setting the electric control lock, or the switch door 8 can be locked and unlocked manually.
The lifting device 7 is arranged on a base plate 9 in the center of the dangerous area 4, the rotating device 5 is arranged on the lifting device 7, the lifting device 5 can adopt an air cylinder or a manually-adjusted lifting rod, the rotating device 5 is arranged at the top end of the electric or manual lifting rod through a bearing, and the rotating device 5 can freely rotate around the lifting rod horizontally.
The sleeve rope 6 one end is fixed on rotary device 5, and the other end is used for covering on the neck of participation experiment cat, and rotary device 5 can rotate along with sleeve rope 6, avoids because of the cat of participation experiment can twine on rotary device 5 when running in danger area 4, thereby adjusts the range of motion of participation experiment cat through the length of lift pole adjustment sleeve rope 6 horizontal direction, when lift pole risees, reduces the range of motion of participation experiment cat, when lift pole descends, increases the range of motion of participation experiment cat, in order to guarantee the safety of rat, makes it unable rat that touches danger area 4 edge through the range of motion of participation experiment cat of lifting device 5 adjustment.
Preferably, the outer ring plate 1 and the inner ring plate 3 are identical in shape and coaxially arranged, the outer ring plate 1 and the inner ring plate 3 can be round or regular polygon, in this embodiment, the outer ring plate 1 and the inner ring plate 3 are regular octagons, and eight escape openings 31 are respectively formed in the centers of the bottoms of eight vertical plate bodies of the regular octagon inner ring plate 3.
In order to control the lifting device 7 and the electric control buckle 8 of the experimental device, a control device for man-machine interaction can be additionally arranged, the input end of the lifting device 7 is connected to the control device, the input end of a driving device connected with the buckle 8 is also connected to the control device, and the states of the lifting device 7 and the buckle 10 are adjusted in a key or touch mode.
The operation mode of the experimental device is as follows:
the neck of the cat participating in the experiment is sleeved on the sleeve rope 6, one or a plurality of escape openings 31 are selected, the buckles 10 corresponding to the selected escape openings 31 are unlocked, the corresponding switch doors 8 can be opened, the rest switch doors 8 are in a locking state, then the rat is placed into the danger area 4, the cat sees the rat to start to catch up with the rat, the rat can only strike the corresponding switch doors 8 from the selected escape openings 31 to enter the safety area 2, the cat cannot enter the safety area 2, the memory degree of the rat on the escape openings 31 is detected through multiple experiments, and therefore the cognitive function of the rat is detected.
The experimental device simplifies the judgment of the cognition of the rat, not only ensures that cats participate in the experiment well, but also ensures the safety of rats participating in the experiment, has simple structure, convenient use and visual effect, and can reflect the cognition function of the rat comprehensively and objectively.
It should be noted that the foregoing description is only a preferred embodiment of the present invention, and the present invention is not limited to the foregoing embodiment, and should be construed as falling within the scope of the present invention as long as the technical effects of the present invention are achieved by the same means.
Claims (7)
1. Experimental device for detect rat cognitive function that cat participated in, its characterized in that:
comprises an outer ring plate (1), an inner ring plate (3), a switch door (8), a rotating device (5), a lifting device (7) and a sleeve rope (6);
the outer ring plate (1) is arranged on the base plate (9), the inner ring plate (3) is arranged on the base plate (9) in the outer ring plate (1), an annular area enclosed between the inner ring plate (3) and the outer ring plate (1) is a safety area (2), the area in the inner ring plate (3) is a danger area (4), a plurality of escape openings (31) are uniformly formed in the inner ring plate (3), switch doors (8) for opening the safety area (2) are respectively arranged at the escape openings (31), and the corresponding escape openings (31) are closed when the switch doors (8) are closed;
the lifting device (7) is arranged on a base plate (9) in the center of the dangerous area (4), and the rotating device (5) is arranged on the lifting device (7) and can freely rotate on a horizontal plane;
one end of the sleeve rope (6) is connected to the rotating device (5), and the other end of the sleeve rope is used for sleeving cats participating in the experiment.
2. An experimental set-up for the detection of cognitive function in rats involving cats as claimed in claim 1, wherein: the outer ring plate (1) and the inner ring plate (3) are identical in shape.
3. An experimental set-up for the detection of cognitive function in rats involving cats as claimed in claim 2, wherein: the outer ring plate (1) and the inner ring plate (3) are round.
4. An experimental set-up for the detection of cognitive function in rats involving cats as claimed in claim 2, wherein: the outer ring plate (1) and the inner ring plate (3) are both regular polygons.
5. An experimental set-up for the detection of cognitive function in rats involving cats as claimed in claim 4, wherein: the outer ring plate (1) and the inner ring plate (3) are regular hexagons or regular octagons.
6. An experimental set-up for the detection of cognitive function in rats involving cats as claimed in claim 5, wherein: the escape openings (31) are arranged at the bottoms of the side plate bodies of the inner ring plate (3).
7. An experimental device for detecting cognitive function in rats involving a cat according to any one of claims 1 to 6 wherein: the switch door (8) is a side-by-side door or a side-hung door.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910318761.4A CN109892247B (en) | 2019-04-19 | 2019-04-19 | Experimental device for detect rat cognitive function of cat participation |
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| CN201910318761.4A CN109892247B (en) | 2019-04-19 | 2019-04-19 | Experimental device for detect rat cognitive function of cat participation |
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| CN109892247A CN109892247A (en) | 2019-06-18 |
| CN109892247B true CN109892247B (en) | 2023-08-18 |
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| CN113384231B (en) * | 2021-05-28 | 2023-06-09 | 温州医科大学 | Experimental device and method for guiding mice to find escape platform through visual clues |
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