CN109881267A - Artificial blood vessel's draft machine based on electrostatic spinning - Google Patents
Artificial blood vessel's draft machine based on electrostatic spinning Download PDFInfo
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- CN109881267A CN109881267A CN201910209650.XA CN201910209650A CN109881267A CN 109881267 A CN109881267 A CN 109881267A CN 201910209650 A CN201910209650 A CN 201910209650A CN 109881267 A CN109881267 A CN 109881267A
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- China
- Prior art keywords
- blood vessel
- spray head
- axis
- electrostatic spinning
- artificial blood
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- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 68
- 239000002473 artificial blood Substances 0.000 title claims abstract description 25
- 238000010041 electrostatic spinning Methods 0.000 title claims abstract description 18
- 239000007921 spray Substances 0.000 claims abstract description 70
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000002347 injection Methods 0.000 claims abstract description 5
- 239000007924 injection Substances 0.000 claims abstract description 5
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000009987 spinning Methods 0.000 abstract description 15
- 238000002360 preparation method Methods 0.000 abstract description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 210000003781 tooth socket Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
The invention discloses a kind of artificial blood vessel's draft machine based on electrostatic spinning, belong to blood vessel preparation field, axis is collected including two or more blood vessels, every blood vessel collects axis and is furnished with one group of spinneret, every group of spinneret includes more than two spray heads for being located at and collecting below axis, upward, each spray head of every group of spinneret can reach each position immediately below blood vessel collection axis by the driving of mobile mechanism to the injection direction of spray head.The present invention carries out spinning using the spray head sprayed upwards, not will form " dropping liquid ", guarantees the integrality for preparing artificial blood vessel, and every blood vessel collects axis and is equipped with more than two spray heads, so that the uniformity and efficiency of spinning are also higher.
Description
Technical field
The present invention relates to artificial blood vessel's manufacturing fields, prepare more particularly to a kind of artificial blood vessel based on electrostatic spinning
Machine.
Background technique；
It is at present usually to collect single spray head setting above axis by artificial blood vessel prepared by electrostatic spinning mode, it
Rear from top to bottom spinneret and fall in and collect axis surface.However, artificial blood vessel is special for the integrality and uniformity requirement of material
Not high, because there is the case where " dropping liquid " in this mode, it is difficult to ensure that the integrality of artificial blood vessel, and single spray head is spun
Its uniformity of silk and efficiency are also low.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of artificial blood vessel's draft machine based on electrostatic spinning, can uniformly,
Quick spinning.
The technical scheme adopted by the invention is that:
A kind of artificial blood vessel's draft machine based on electrostatic spinning collects axis including two or more blood vessels, and every blood vessel collects axis
Equipped with one group of spinneret, every group of spinneret includes more than two spray head for being located at and collecting below axis, the injection direction of spray head upward,
Each spray head of every group of spinneret can reach each position immediately below blood vessel collection axis by the driving of mobile mechanism.
As a further improvement of the present invention, the mobile mechanism includes translating device, and the translating device drives spray head
Translation so that reach each position immediately below blood vessel collection axis in the horizontal direction.
As a further improvement of the present invention, the translating device includes horizontally disposed guide rail and matches with guide rail sliding
Each spray head of the jet nozzle of conjunction, difference group spinneret is each attached to the different location of jet nozzle.
As a further improvement of the present invention, the guide rail and jet nozzle are racetrack, and spray head is connected to jet nozzle
Long side on, and the long side of jet nozzle be located at blood vessel collect axis immediately below.
As a further improvement of the present invention, the position that moves horizontally positioned at the spray head of the same long side of jet nozzle is limited in this
Long side.
As a further improvement of the present invention, the spray head includes liquid disk and the nozzle needle that passes perpendicularly through in the middle part of liquid disk, institute
It states liquid disk outer wall and offers return port.
As a further improvement of the present invention, each spray head is respectively provided with a syringe and by the independent feed flow of the syringe.
As a further improvement of the present invention, the mobile mechanism includes lifting device, the lifting device driving translation
Device is vertically gone up and down, so that each spray head collects axis close to or far from corresponding blood vessel.
As a further improvement of the present invention, the translating device is located on horizontal demarcation plate, and blood vessel collects axle position
Above demarcation plate, the component of spinneret feed flow is located at below demarcation plate, the lifting device drives the demarcation plate lifting.
As a further improvement of the present invention, blood vessel is collected and is provided with heating device above axis.
The beneficial effects of the present invention are: the present invention carries out spinning using the spray head sprayed upwards, " dropping liquid " not will form,
The integrality of artificial blood vessel can be guaranteed to prepare, and every blood vessel collects axis and is equipped with more than two spray heads, spinning
Uniformity and efficiency are also higher.
Detailed description of the invention
The present invention is further described with embodiment with reference to the accompanying drawing.
Fig. 1 is vertical planning drawing of the invention；
Fig. 2 is the horizontally disposed figure of translating device and spray head；
Fig. 3 is the structural schematic diagram of spray head.
Specific embodiment
Artificial blood vessel's draft machine based on electrostatic spinning as depicted in figs. 1 and 2, the blood vessel including eight metal materials are received
Collect axis 1, every blood vessel collects axis 1 and is furnished with one group of spinneret, and every group of spinneret includes two spray heads 2, and each spray head 2 is respectively positioned on correspondence
The lower section of blood vessel collection axis 1.Certainly, blood vessel, which collects axis, can be two or three or more, and the spray of every group of spinneret
Head can also be with more than two, these are all to be configured according to actual needs.
It is typically all to be parallel to each other and be located at sustained height that each blood vessel, which collects axis 1, so that uniform when entire machine spinning,
Being adjusted also being capable of consistent adjustment simultaneously.
Upward, external positive high voltage is electric for the injection direction of spray head 2 in embodiment, and blood vessel collects the external negative high voltage of axis 1
Electricity.The mode of this spinneret from the bottom to top can be avoided effectively " dropping liquid " in spinning process, guarantee preparation artificial blood vessel's wall
Integrality.
In addition, each spray head 2 of every group of spinneret can reach blood vessel collection by the driving of mobile mechanism in embodiment
Each position immediately below axis 1.Specifically, blood vessel collects axis and is projected as a line segment in the plane where spray head, and passes through
Mobile mechanism, corresponding spray head can sequentially reach any position of the line segment；Simultaneously by mobile mechanism, corresponding spray head can be with
It goes up and down and reaches any height and position below blood vessel collection axis.
The movement of above-mentioned this spray head can be controlled by computer, or by manually controlling, be also possible to computer
It controls and manually controls and jointly control.
It is further preferred that mobile mechanism includes translating device, translating device drives each spray head 2 to put down in the same plane
It moves, so that each spray head reaches each position that blood vessel collects 1 underface of axis in the horizontal direction comprising blood vessel collects axial projection
Any one point on two endpoints of line segment and the line segment.
It is further preferred that controlling and simplifying structure for convenience, each spray head 2 is gone to drive by same set of translating device.
Specifically, translating device includes horizontally disposed guide rail 3 and the jet nozzle 4 that is slidably matched with guide rail 3, difference group spinnerets
Each spray head 2 is each attached to the different location of jet nozzle 4.Jet nozzle 4 is able to drive spray head along the sliding of guide rail 3 and reaches different water
Prosposition is set.In embodiment, each spray head of each group of spinneret only corresponds to a blood vessel and collects axis, without being moved to other blood
The lower section of pipe collection axis.
It is further preferred that guide rail 3 and jet nozzle 4 are racetrack, it is provided in the medial surface of 4 post position of jet nozzle
Tooth socket or key way, the i.e. jet nozzle 4 can be regarded as a chain, drive the sprocket wheel of the jet nozzle 4 or gear to be located at and run
The inner ring position in road, sprocket wheel or gear drive the translation of jet nozzle 4 on guides 3 by rotating forward, inverting.Above-mentioned spray head
2 are connected in the long side of jet nozzle 4, and the long side of jet nozzle 4 is located at blood vessel and collects immediately below axis 1.
It is further preferred that the position that moves horizontally for being located at the spray head of the same long side of jet nozzle 4 is limited in the long side, that is, spray
Position of the head without departing from long side.In view of spray head is needed through the external high-voltage electricity of route, if jet nozzle 4 carries out loop back
Movement or rotation path are too long, then route can be intertwined, then only needing to be controlled by sprocket wheel or gear in embodiment
Jet nozzle 4 carries out the rotating forward of setting stroke, carries out the reversion of setting stroke later, successively rotates, to guarantee that spray head 2 does not depart from
Long side position.
It is further preferred that spray head 2 includes liquid disk 21 and the nozzle needle passed perpendicularly through in the middle part of liquid disk 21 with reference to Fig. 3
22, the outer wall of liquid disk 21 extends to form internally positioned hollow form cavity upwards, and the cavity of the hollow form can accept spray head 2
Place is also provided with return port 23 because of residual liquid after injection, in 21 outer wall of liquid disk, and the direction of return port 23 is towards racetrack
The middle part of jet nozzle 4, above-mentioned residual liquid are flowed out from return port 23, are dropped downward into being arranged below jet nozzle 4 and not shown
Collecting part in, passed through again by collecting part and input each spray head after circulation and re-use, the waste of raw material is reduced with this.
It is further preferred that each spray head 2 is respectively provided with a syringe 24, for spinning solution to be input to spray head, and
The spray head is corresponded by the independent feed flow of the syringe, i.e., each spray head and each syringe.Each spray head can be individually for matching
Pair blood vessel collect the spinning of axis hydrojet, without simultaneously spinning, in general carry out artificial blood vessel's spinning preparation when, each group
Each spray head of spinneret is to work at the same time.
In embodiment, position of each spray head 2 on jet nozzle 4 is adjustable namely same group of two neighboring spray
The spacing of head is adjustable；The spacing of the spray head of difference group is also adjustable, is collected with adapting to the blood vessel of different length and position
Axis 1.In this case, spray head 2 and jet nozzle 4 are arranged to removable connection.
It is further preferred that above-mentioned mobile mechanism further includes lifting device, lifting device drives translating device vertical
The upper vertical lifting gone up and down to drive spray head 2, so that each spray head 2 collects axis 1 close to or far from corresponding blood vessel.Before and after spinning,
Spray head 2 and blood vessel, which collect the height between axis 1, not can infinitely shorten, and be controlled in a certain distance, only
The lifting distance of translating device can be arranged larger in design.
Specifically, translating device is located on horizontal demarcation plate 5, blood vessel collects axis 1 and is located at 5 top of demarcation plate, to spinning
It is located at 5 lower section of demarcation plate if the component (such as liquid-supplying system, syringe) of silk head feed flow, the lifting device drives demarcation plate 5
Go up and down the lifting to drive translating device.Lifting device may include hydraulic cylinder (cylinder), and output end is directly or indirectly
Demarcation plate 5 is connected, for example passes through telescopic mast 51, the flexible lifting that can control demarcation plate 5 of hydraulic cylinder (cylinder).Lifting device
The demarcation plate 5 can also be driven by the way of lifting motor.
It is further preferred that the top that blood vessel collects axis 1 is additionally provided with and heating device (not shown), to control spinning
Temperature, corresponding collect in blood vessel be provided with and temperature sensor (not shown) near axis 1.The rear of spray head 2 and blood
The rear that pipe collects axis 1 is additionally provided with and headlamp (not shown), to observe the situation of spinning.
The above is the preferred embodiment of the present invention, is not constituted a limitation on the scope of protection of the present invention.
Claims (10)
1. a kind of artificial blood vessel's draft machine based on electrostatic spinning, it is characterised in that: collect axis including two or more blood vessels, often
Root blood vessel collects axis and is furnished with one group of spinneret, and every group of spinneret includes more than two spray heads being located at below blood vessel collection axis, spray
Upward, each spray head of every group of spinneret can be reached under blood vessel collects axis just the injection direction of head by the driving of mobile mechanism
Each position of side.
2. artificial blood vessel's draft machine according to claim 1 based on electrostatic spinning, it is characterised in that: the mobile mechanism
Including translating device, the translating device driving spray head translation is each immediately below blood vessel collection axis to reach in the horizontal direction
A position.
3. artificial blood vessel's draft machine according to claim 2 based on electrostatic spinning, it is characterised in that: the translating device
Including horizontally disposed guide rail and the jet nozzle being slidably matched with guide rail, each spray head of difference group spinneret is each attached to spray head
The different location of frame.
4. artificial blood vessel's draft machine according to claim 3 based on electrostatic spinning, it is characterised in that: the guide rail and spray
Head frame is racetrack, and spray head is connected in the long side of jet nozzle, and the long side of jet nozzle is located at blood vessel and collects immediately below axis.
5. artificial blood vessel's draft machine according to claim 4 based on electrostatic spinning, it is characterised in that: it is same to be located at jet nozzle
The position that moves horizontally of the spray head of one long side is limited in the long side.
6. artificial blood vessel's draft machine according to claim 1 based on electrostatic spinning, it is characterised in that: the spray head includes
Liquid disk and the nozzle needle passed perpendicularly through in the middle part of liquid disk, the liquid disk outer wall offer return port.
7. artificial blood vessel's draft machine according to claim 1 or 2 or 3 or 4 or 5 or 6 based on electrostatic spinning, feature exist
In: each spray head is respectively provided with a syringe and by the independent feed flow of the syringe.
8. artificial blood vessel's draft machine according to claim 1 or 2 or 3 or 4 or 5 or 6 based on electrostatic spinning, feature exist
In: the mobile mechanism includes lifting device, and the lifting device driving translating device is vertically gone up and down, so that each spray head leans on
Axis is collected close or remote from corresponding blood vessel.
9. artificial blood vessel's draft machine according to claim 8 based on electrostatic spinning, it is characterised in that: the translating device
It is located on horizontal demarcation plate, blood vessel collects axle position above demarcation plate, is located under demarcation plate to the component of spinneret feed flow
Side, the lifting device drive the demarcation plate lifting.
10. artificial blood vessel's draft machine according to claim 1 or 2 or 3 or 4 or 5 or 6 based on electrostatic spinning, feature
Be: blood vessel is collected and is provided with heating device above axis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910209650.XA CN109881267A (en) | 2019-03-19 | 2019-03-19 | Artificial blood vessel's draft machine based on electrostatic spinning |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910209650.XA CN109881267A (en) | 2019-03-19 | 2019-03-19 | Artificial blood vessel's draft machine based on electrostatic spinning |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109881267A true CN109881267A (en) | 2019-06-14 |
Family
ID=66933069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910209650.XA Pending CN109881267A (en) | 2019-03-19 | 2019-03-19 | Artificial blood vessel's draft machine based on electrostatic spinning |
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| Country | Link |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111317594A (en) * | 2020-02-28 | 2020-06-23 | 广州迈普再生医学科技股份有限公司 | Automatic artificial blood vessel production device |
| CN112647196A (en) * | 2020-12-29 | 2021-04-13 | 李启虎 | Fiber spinning machine and spinning technology |
| CN112760732A (en) * | 2020-12-25 | 2021-05-07 | 佛山轻子精密测控技术有限公司 | Mask-matched spinning system |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111317594A (en) * | 2020-02-28 | 2020-06-23 | 广州迈普再生医学科技股份有限公司 | Automatic artificial blood vessel production device |
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| CN112760732A (en) * | 2020-12-25 | 2021-05-07 | 佛山轻子精密测控技术有限公司 | Mask-matched spinning system |
| CN112760732B (en) * | 2020-12-25 | 2021-12-03 | 佛山轻子精密测控技术有限公司 | Mask-matched spinning system |
| CN112647196A (en) * | 2020-12-29 | 2021-04-13 | 李启虎 | Fiber spinning machine and spinning technology |
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