CN109850206B - Realize online sterilization apparatus of glass water needle production line filling system - Google Patents
Realize online sterilization apparatus of glass water needle production line filling system Download PDFInfo
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- CN109850206B CN109850206B CN201910251013.9A CN201910251013A CN109850206B CN 109850206 B CN109850206 B CN 109850206B CN 201910251013 A CN201910251013 A CN 201910251013A CN 109850206 B CN109850206 B CN 109850206B
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Abstract
An online sterilization device for realizing a filling system of a glass water needle production line comprises a multi-way liquid separator, a plunger pump and a filling needle, wherein a glass multi-way liquid inlet pipe is arranged at the bottom of the multi-way liquid separator, a first silica gel hose is sleeved on the glass multi-way liquid inlet pipe and is connected with an outlet at the bottom of a liquid storage tank, and the liquid storage tank is also connected with a steam pipe; the utility model discloses a syringe needle, including the syringe needle portion, the syringe needle portion is irritated needle, the multichannel knockout top is equipped with the drain pipe that a plurality of equidistance distribute, the second silica gel hose has been put to the cover on the drain pipe, the second silica gel hose passes through the connecting pipe and is connected with the input of plunger pump, the output of plunger pump passes through the third silica gel hose and is connected with the syringe needle portion of irritating the needle, the needle tubing portion of irritating the needle passes the disinfection tube head cover and puts in fourth silica gel hose one end mouth, the afterbody and the fourth silica gel hose connection of. The tube end of the fourth silica gel hose is connected with the needle tube sealing device. The invention has the characteristics of reducing the cost and reducing the number of unqualified products.
Description
Technical Field
The invention relates to the technical field, in particular to an online sterilization device for a filling system of a glass water needle production line.
Background
At present, generally, after a liquid medicine storage tank is sterilized, a post person needs to transfer and assemble another set of sterilized filling system, the filling system consists of 82 parts, 2 persons are equipped at a filling post, and the time for disassembling and assembling the filling system is 21 minutes. Therefore, the operation is complicated, the working efficiency is low, and the pressure of workers is high. Because of the many components, the plunger pump, the silicone tube, and the filling needle need to be fixed to the filling machine after being connected or fastened to each other, and the position of the filling needle needs to be corrected, which may cause the sterilized filling system to be contaminated.
In addition, the pulsation high-temperature sterilization has the problems that the pipe joint is not tightly closed, air leakage is easy, the pressure is unstable, a temperature probe is easy to damage, air is easy to leak and the like, and the sterilization quality is directly influenced by the problems.
Disclosure of Invention
The invention aims to provide an online sterilization device for a filling system of a glass water needle production line, so as to solve the problems in the background technology.
The technical scheme adopted by the invention is as follows: an online sterilization device for realizing a filling system of a glass water needle production line comprises a multi-way liquid separator, a plunger pump and a filling needle, wherein a glass multi-way liquid inlet pipe is arranged at the bottom of the multi-way liquid separator, a first silica gel hose is sleeved on the glass multi-way liquid inlet pipe and is connected with an outlet at the bottom of a liquid storage tank, and the liquid storage tank is also connected with a steam pipe; the top of the multi-way liquid separator is provided with a plurality of liquid outlet pipes which are distributed equidistantly, a second silica gel hose is sleeved on the liquid outlet pipes and connected with the input end of a plunger pump through a connecting pipe, the output end of the plunger pump is connected with the needle head part of an irrigation needle through a third silica gel hose, the needle tube part of the irrigation needle penetrates through a disinfection tube head and is sleeved in a tube port at one end of a fourth silica gel hose, the tail part of the disinfection tube head is connected with the fourth silica gel hose, the side part of the disinfection tube head is connected with a fixing frame, the part of the fourth silica gel hose, in which the needle tube part of the irrigation needle is sleeved, is movably connected with a needle tube sealing device, the other end of the fourth silica gel hose is connected with an interface of a sealing cover, the interface is uniformly arranged at the top of the sealing cover, the bottom of the sealing cover is provided with a drain pipe; a pipeline is arranged on the side portion of the sealing cover, and a temperature probe penetrates through the pipeline.
Preferably, the needle tube sealing device comprises a servo motor, a fastening screw rod and a tube hoop, and the end part of the fastening screw rod is connected with a rotating shaft of the servo motor; the fastening screw rod is formed by connecting a plurality of fastening screw rods, a positive screw section and a negative screw section are arranged on the fastening screw rod, fastening nut sleeves are respectively screwed on the positive screw section and the negative screw section, the positive screw section and the negative screw section are connected through a connecting piece, and the fastening nut sleeves are respectively fixed at the port of the locking pliers.
Preferably, a pipe hoop is arranged in a jaw of the locking pliers, two butt ends of the pipe hoop are respectively provided with an occlusion notch, the occlusion notches are correspondingly occluded with each other, so that the silicone hose is comprehensively locked, and the filling needle is locked in the silicone hose.
Preferably, the top of the plunger pump is provided with a temperature verification probe.
Preferably, the inner diameters of the first, second, third and fourth silicone hoses are all 4.7 mm.
As preferred, first silicone hose includes main silicone tube, main silicone tube outside cover is equipped with the metal mesh cover, main silicone tube tip region is fitted with a contraceptive ring and is equipped with the friction granule, and the friction granule surpasss metal mesh cover mesh, can increase the frictional force of silicone hose and metal mesh cover, and the locking ribbon of being convenient for is operated, prevents that it from droing under high-pressure impact. The multilayer structure can stop the problem of steam leakage.
As preferred, first silica gel hose can also be the high temperature silica gel body, the high temperature silica gel body is two-layer, and inlayer high temperature silica gel body inner chamber is hollow structure, is equipped with the aramid fiber intermediate layer between the adjacent two-layer high temperature silica gel body.
Preferably, the second, third and fourth silicone hoses have the same structure as the first silicone hose.
Preferably, the temperature probe comprises a stainless steel threaded sleeve, a medical polyamide threading pipe, a temperature sensing element and a temperature measuring cable, the medical polyamide threading comprises an integrally formed front-end temperature sensing sleeve, the stainless steel threaded sleeve is sleeved on a large-diameter seam allowance at the rear part of the front-end temperature sensing sleeve, the temperature sensing element is arranged in the front-end temperature sensing sleeve and is electrically connected with the temperature measuring cable which extends to the outside after penetrating through the medical polyamide threading pipe, heat insulation glue for fixing the temperature measuring cable is filled in the medical polyamide threading pipe, and the heat insulation glue is ketoxime type room temperature curing silicone rubber.
Preferably, the front end of the stainless steel threaded sleeve is further sleeved with a sealing ring, and a high-temperature heat-conducting glue for fixing the temperature sensing element is further filled in the front-end temperature sensing sleeve and is made of a medical epoxy resin material.
The invention has the characteristics of reducing labor, reducing cost, saving time and reducing the number of unqualified products. The sterilization temperature of the invention is set at 100-. Therefore, the traditional sterilization mode is changed, the pollution risk is reduced, the product quality guarantee level is improved, and the online sterilization is thoroughly realized.
Drawings
FIG. 1 is a schematic view of a portion of the structure of the present invention;
FIG. 2 is a schematic structural view of another part of FIG. 1;
FIG. 3 is a schematic view of the needle cannula sealing device of the present invention;
FIG. 4 is a schematic view of a ferrule of the syringe sealing apparatus of the present invention;
FIG. 5 is a top view of a ferrule in the needle sealing device of the present invention;
FIG. 6 is a schematic structural view of a silicone hose according to the present invention;
FIG. 7 is a sectional view of a silicone hose of the present invention;
FIG. 8 is a cross-sectional view of another silicone hose of the present invention;
FIG. 9 is a schematic view of the structure of the temperature probe of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in the figure 1-2, the device for realizing the online sterilization of the filling system of the glass water needle production line comprises a multi-way liquid separator 2, a plunger pump 31, a connecting pipe 33, a filling needle 61, a sealing cover 7, a drain valve 72 and a temperature probe 71, wherein a glass multi-way liquid inlet pipe is arranged at the bottom of the multi-way liquid separator 2, and the length of the glass multi-way liquid inlet pipe is 58-62 mm. A first silica gel hose 22 is sleeved on the glass multi-way liquid inlet pipe, two locking ribbons 23 are bound on the first silica gel hose 22, and the first silica gel hose 22 is connected with an outlet at the bottom of the liquid storage tank 1; the liquid tank 1 is connected to a steam pipe 9. The utility model discloses a syringe needle, including multichannel knockout 2, the drain pipe 21 that is equipped with a plurality of equidistance distributions on the top, second silica gel hose 3 has been put to the cover on the drain pipe, second silica gel hose 3 passes through connecting pipe 33 and is connected with plunger pump 31's input, and the top of plunger pump is equipped with temperature and verifies probe 32, the output of plunger pump 31 passes through third silica gel hose 5 and irritates the syringe needle portion of needle 61 and be connected, irritate the needle tubing portion of needle 61 and pass disinfection tube head 921 cover and put in 8 one end mouths of tubes of fourth silica gel hose. And a locking binding belt 81 can be bound at the joint of the fourth silica gel hose 8 and the needle tube part of the irrigation needle. The tail part of the disinfection tube head 921 is connected with the fourth silica gel hose, and the lateral part of the disinfection tube head 921 is connected with the fixing frame 92. The part of the fourth silica gel hose 8 sleeved with the needle filling tube part is movably connected with the needle sealing device 62.
3-5, the needle tube sealing device comprises a servo motor 621, a fastening screw 622, and a tube hoop 629, wherein the end of the fastening screw 622 is connected with the rotating shaft of the servo motor 621; the fastening screw 622 is formed by connecting a plurality of fastening screw shafts, a positive screw section 625 and a negative screw section 626 are arranged on each fastening screw shaft, fastening nut sleeves 624 are respectively screwed on the positive screw section 625 and the negative screw section 626, the positive screw section 625 and the negative screw section 626 are connected through a connecting piece 627, the fastening nut sleeves 624 are respectively fixed at the ports of locking pliers 628, a pipe hoop 629 is arranged in a jaw of the locking pliers 628, two opposite ends of the pipe hoop 629 are respectively provided with an occlusion notch 6291, the occlusion notches 6291 are correspondingly occluded with each other, so that the silicone hose is comprehensively locked, and the filling needle 61 is locked in the silicone hose.
Starting the servo motor 621, driving a positive thread section 625 and a negative thread section 626 on a thread shaft to rotate by a rotating shaft of the servo motor 621, further driving the fastening nut sleeve 624 to move oppositely, driving a pipe hoop 629 in the locking clamp 628 to lock the rubber pipe by the fastening nut sleeve 624, and completing the sealing of the needle pipe; be equipped with draw-in groove 630 in the connecting piece, the one end at the anti-silk section is fixed to draw-in groove 630, the one end of positive silk section 625 is equipped with draw-in groove inserted block 631, draw-in groove inserted block 631 and draw-in groove 630 looks lock. The cross sections of the clamping groove 630 and the clamping groove insert block 631 are polygonal columns such as a square column, a hexagonal column and an octagonal column. The servo motor 621 can stably drive the screw shaft to lock and release the rubber pipe,
the other end of the fourth silica gel hose 8 is connected with the interface of the sealing cover 7, the interface is uniformly arranged at the top of the sealing cover, a drain pipe 73 is arranged at the bottom of the sealing cover, the drain pipe 73 is in flange connection with a drain valve 72, and the drain valve 72 is in flange connection with a drainage collecting pipe. A pipeline is arranged on the side part of the sealing cover 7, and a temperature probe 71 is arranged in the pipeline in a penetrating way. The temperature probe 71 is connected to an external temperature controller to record and display sterilization temperature, time and trend.
As can be seen from fig. 6 to 7, the second, third and fourth silicone hoses have the same structure as the first silicone hose. The inner diameters of the first, second, third and fourth silica gel hoses are all 4.7 mm. The first silicone hose comprises a main silicone tube 224, and a metal mesh 223 is sleeved on the outer side of the main silicone tube 224. The regional ring of main silicone tube 224 pipe end portion is equipped with friction granule, and friction granule surpasss metal mesh cover 223 mesh, can increase the frictional force of silica gel hose and metal mesh cover, and the locking ribbon 23 of being convenient for is operated, prevents that it from droing under high-pressure impact. The multilayer structure can stop the problem of steam leakage.
As can be known from fig. 8, the first silica gel hose 22 can also be a high-temperature silica gel tube body 311, the high-temperature silica gel tube body 311 is two-layer, the inner cavity of the innermost high-temperature silica gel tube body 311 is of a hollow structure, an aramid interlayer 312 is arranged between two adjacent high-temperature silica gel tube bodies, and the aramid interlayer 312 is made of an aramid material.
According to the structure, the utility model discloses an optimize whole structure of arranging, set up two-layer and above high temperature silica gel body 311, through pressing from both sides between high temperature silica gel body 311 and establish aramid fiber intermediate layer 312, aramid fiber intermediate layer 312 is preferred to be adopted aramid fiber material to make, and aramid fiber material adopts current medicine level material, improves heat-resisting effect. The second, third and fourth silica gel hoses have the same structure as the first silica gel hose.
As can be seen from fig. 9, the temperature probe 71 includes a stainless steel threaded sleeve 75, a medical polyamide threading tube 710, a temperature sensing element and a temperature measuring cable 74, the medical polyamide threading tube 710 includes an integrally formed front temperature sensing sleeve 76, the stainless steel threaded sleeve 75 is sleeved on a large-diameter seam allowance at the rear portion of the front temperature sensing sleeve 76, the temperature sensing element is arranged in the front temperature sensing sleeve 76, the temperature sensing element is electrically connected with the temperature measuring cable 74 extending to the outside after passing through the medical polyamide threading tube 710, a heat insulating glue for fixing the temperature measuring cable is filled in the medical polyamide threading tube 710, and the heat insulating glue is ketoxime type room temperature curing silicone rubber. The temperature probe can be connected with a control terminal to realize the control of the sterilization time and temperature.
The front end of the stainless steel threaded sleeve 75 is also sleeved with a sealing ring 751. The front-end temperature sensing sleeve 76 is filled with high-temperature heat-conducting glue for fixing a temperature sensing element, and the high-temperature heat-conducting glue is made of medical epoxy resin materials. The condition of water filling inside the temperature probe caused by untight sealing can not occur, and the service life of the temperature probe is prolonged.
The working principle is as follows: the air extraction opening of the sealing cover 7 is connected with a vacuum pump, and cold air in the sealing cover 7 is pumped out to be in a negative pressure state.
The liquid preparation station conveys injection water to wash the liquid medicine pipeline and the filling system, after the cleaning is finished, the compressed air exhausts the residual water in the systems such as the liquid storage tank and the like, and the liquid storage tank and the liquid preparation pipeline carry out 100-fold sterilization by pure steam at 130 ℃; pure steam sequentially passes through the first silica gel hose 22, the multi-way liquid distributor 2, the second silica gel hose 3, the connecting pipe 33, the plunger pump 31, the third silica gel hose 5, the filling needle 61 and the fourth silica gel hose 8, enters the sealing cover 7 to be collected, and finally, whether the terminal temperature reaches 100-plus-130 ℃ is verified through the temperature verification probe. Repeating the above steps for 3 or 4 times, and sterilizing for 1-30 min. Under the action of high temperature and high pressure, the protein of microbe is denatured and coagulated to inactivate and reach the requirement of sterilization. After sterilization, vacuum is applied to rapidly dry the sterilized articles. The invention fastens the connecting part of the filling system, realizes the sealing of the filling needle and finally realizes the synchronous sterilization with the liquid preparation pipeline system.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (1)
1. An online sterilization device for realizing a filling system of a glass water needle production line comprises a multi-way liquid separator, a plunger pump and a filling needle, and is characterized in that a glass multi-way liquid inlet pipe is arranged at the bottom of the multi-way liquid separator, a first silica gel hose is sleeved on the glass multi-way liquid inlet pipe and is connected with an outlet at the bottom of a liquid storage tank, and the liquid storage tank is also connected with a steam pipe; the top of the multi-way liquid separator is provided with a plurality of liquid outlet pipes distributed at equal intervals, the liquid outlet pipes are sleeved with second silica gel hoses, the second silica gel hoses are connected with the input end of a plunger pump through connecting pipes, the output end of the plunger pump is connected with the needle head part of an irrigation needle through a third silica gel hose, the needle head part of the irrigation needle penetrates through a disinfection tube head and is sleeved in a tube port of a fourth silica gel hose, the tail part of the disinfection tube head is connected with the fourth silica gel hose, the side part of the disinfection tube head is connected with a fixed frame, the part sleeved with the needle head part of the irrigation needle in the fourth silica gel hose is movably connected with a needle sealing device, the other end of the fourth silica gel hose is connected with an interface of a sealing cover, the interface is uniformly arranged at the top of the sealing cover, the bottom of the sealing cover is provided with a drain pipe, the drain pipe is connected with a drain valve flange, a temperature probe penetrates through the pipeline; the needle tube sealing device comprises a servo motor, a fastening screw rod and a tube hoop, wherein the end part of the fastening screw rod is connected with a rotating shaft of the servo motor; the fastening screw rod is formed by connecting a plurality of fastening screw rods, a positive screw section and a negative screw section are arranged on each fastening screw rod, fastening nut sleeves are respectively screwed on the positive screw section and the negative screw section, the positive screw section and the negative screw section are connected through a connecting piece, and the fastening nut sleeves are respectively fixed at the ports of the locking pliers; the temperature probe comprises a stainless steel threaded sleeve, a medical polyamide threading pipe, a temperature sensing element and a temperature measuring cable, the medical polyamide threading comprises an integrally formed front-end temperature sensing sleeve, the stainless steel threaded sleeve is sleeved on a large-diameter seam allowance at the rear part of the front-end temperature sensing sleeve, the temperature sensing element is arranged in the front-end temperature sensing sleeve and is electrically connected with the temperature measuring cable which extends to the outside after penetrating through the medical polyamide threading pipe, heat insulation glue for fixing the temperature measuring cable is filled in the medical polyamide threading pipe, and the heat insulation glue is ketoxime type room temperature curing silicone rubber; a pipe hoop is arranged in a jaw of the locking pliers, two butt ends of the pipe hoop are respectively provided with an occlusion notch, the occlusion notches are correspondingly occluded with each other, so that the silicone hose is comprehensively locked, and the irrigation needle is locked in the silicone hose; the top of the plunger pump is provided with a temperature verification probe; the first silica gel hose comprises a main silica gel tube, a metal net sleeve is sleeved on the outer side of the main silica gel tube, friction particles are annularly arranged in the end area of the main silica gel tube, and the friction particles exceed the meshes of the metal net sleeve; the first silica gel hose can also be a high-temperature silica gel hose body, the high-temperature silica gel hose body is divided into two layers, the inner cavity of the innermost high-temperature silica gel hose body is of a hollow structure, and an aramid fiber interlayer is arranged between two adjacent layers of high-temperature silica gel hose bodies; the inner diameters of the first, second, third and fourth silica gel hoses are all 4.7 mm; the second, third and fourth silica gel hoses have the same structure as the first silica gel hose; the stainless steel thread bush is characterized in that a sealing ring is further sleeved at the front end of the stainless steel thread bush, high-temperature heat-conducting glue used for fixing a temperature sensing element is further filled in the front-end temperature sensing bush, and the high-temperature heat-conducting glue is made of medical epoxy resin materials.
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CN201910251013.9A CN109850206B (en) | 2019-03-29 | 2019-03-29 | Realize online sterilization apparatus of glass water needle production line filling system |
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CN111453013A (en) * | 2020-03-28 | 2020-07-28 | 安徽金三环金属科技有限公司 | From feeding formula medicine packagine machine |
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US5207983A (en) * | 1992-01-29 | 1993-05-04 | Sterling Winthrop Inc. | Method of terminal steam sterilization |
WO2007117228A2 (en) * | 2005-01-25 | 2007-10-18 | Medical Instill Technologies, Inc. | Container and closure assembly for a fat containing liquid product |
CN103083698B (en) * | 2013-02-16 | 2015-07-29 | 淄博康元医疗器械有限公司 | Tri compound sterilizing methods and bactericidal unit |
CN204352225U (en) * | 2014-12-19 | 2015-05-27 | 江西科伦药业有限公司 | The online bactericidal unit of a kind of liquor piping |
CN205868984U (en) * | 2016-07-11 | 2017-01-11 | 楚天科技股份有限公司 | Irritate needle and wash sterilization apparatus |
CN206511159U (en) * | 2016-12-07 | 2017-09-22 | 河南泰丰生物科技有限公司 | A kind of liquid medicine aseptic filling systems |
CN107309892A (en) * | 2017-08-21 | 2017-11-03 | 苏州工业职业技术学院 | A kind of parallel clamping device for robot end |
CN207850553U (en) * | 2018-02-09 | 2018-09-11 | 深圳市铂电科技有限公司 | Fluid temperature (F.T.) is popped one's head in |
CN208053779U (en) * | 2018-03-07 | 2018-11-06 | 廊坊市爱尔血液净化器材厂 | Has the blood perfusion device filling liquid device for casting of on-line cleaning and sterilizing function |
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