CN109817301A - A kind of generation method of medication information warning - Google Patents

A kind of generation method of medication information warning Download PDF

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Publication number
CN109817301A
CN109817301A CN201910070383.2A CN201910070383A CN109817301A CN 109817301 A CN109817301 A CN 109817301A CN 201910070383 A CN201910070383 A CN 201910070383A CN 109817301 A CN109817301 A CN 109817301A
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medicine
variable
information
advise
doctor
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CN201910070383.2A
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吕良忠
俞佳
周晓悦
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Hangzhou Yi Yao Information Technology Co Ltd
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Hangzhou Yi Yao Information Technology Co Ltd
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Abstract

The present embodiments relate to a kind of generation methods of medication information warning, comprising: insertion variable information;Wherein, the variable information includes that medicine advises variable, shares medicine and advise variable, patient variables and doctor's advice variable;Receive the patient ID and corresponding prescription/doctor's advice information of doctor's input;The patient basis of patient is obtained according to the patient ID;The corresponding variate-value of the variable information is obtained to information extraction is carried out in the patient basis and the prescription/doctor's advice information according to the variable information;Assignment is carried out to corresponding variable information according to the variate-value extracted;Corresponding judgment rule is called in knowledge base according to the variable information;Whether the variable information after judging the assignment meets the judgment rule;When not meeting, medication information warning is generated.

Description

A kind of generation method of medication information warning
Technical field
The present invention relates to data processing field more particularly to a kind of generation methods of medication information warning.
Background technique
In recent years, Prescription automatic screening system can quickly and more generally most of clinical application be unreasonable asks for reflection Topic, can be to doctor terminal and nurse end, pharmacist examine square end, dispensing pharmacist end carries out on-line early warning.For example, being embedded into HIS system In doctor workstation, real-time monitoring is carried out to doctor institute prescription/doctor's advice, examine content include administration route, dosage, Administration frequency, delivery time, allergies, contraindication;Solvent selection/incompatibility, interaction and the repetition of injection type are used Medicine, special population medication (old man, children, gestation and nursing women, the bad patient of renal function), examination etc..
The accuracy of Prescription automatic screening system knowledge base prompt information is extremely important.In order to realize the accurate of prompt information Property, it generally requires to make with the medication information of patient, age, weight, body surface area and diagnosis relevant information, doctor's advice information, drug It is connected with the characteristic information of itself.For example, being used for 14 years old or less children, daily administration agent in phenytoin sodium tablet specification Amount should be 3-8mg/kg.Prompt information: 14 years old or less children, daily pharmaceutical quantities should be 3-8mg/kg, still not enough precisely, Wu Faman Sufficient user accurately quickly modifies the requirement of prescription.If patient's children's weight is 10kg, prompt information is answered are as follows: the infant is given daily Pharmaceutical quantities should be 30mg-80mg, just can reach the requirement precisely prompted.Therefore, Prescription automatic screening system knowledge how is improved The accuracy in library is extremely important.
Summary of the invention
It, can the purpose of the present invention is in view of the drawbacks of the prior art, providing a kind of generation method of medication information warning According to variable assignments method to information extraction and assignment is carried out in patient basis and the prescription/doctor's advice information, recalls and know Know judgment rule in library, medication information warning is generated, to promote the accuracy of medication.
In view of this, the embodiment of the invention provides a kind of generation methods of medication information warning, comprising:
It is inserted into variable information;Wherein, the variable information includes that medicine advises variable, shares medicine and advise variable, patient variables and doctor Advise variable;
Receive the patient ID and corresponding prescription/doctor's advice information of doctor's input;
The patient basis of patient is obtained according to the patient ID;
According to the variable information, to carrying out information extraction in the patient basis and the prescription/doctor's advice information, Obtain the corresponding variate-value of the variable information;
Assignment is carried out to corresponding variable information according to the variate-value extracted;
Corresponding judgment rule is called in knowledge base according to the variable information;
Whether the variable information after judging the assignment meets the judgment rule;
When not meeting, medication information warning is generated.
Preferably, the variable information is formula structure or non-formula structure;The variable information of the formula structure includes Sub- variable information and operation rule;The generation medication information warning specifically includes:
Judge whether the variable information is formula structure;
When the variable information is formula structure, the sub- variable information of the variable information is obtained;
It is calculated according to the operation rule of the sub- variable information and the variable information, obtains the medication warning letter Breath.
Preferably, it includes that medicine advises administration route, medicine to advise each dosage, medicine that administration frequency, medicine is advised to advise often that the medicine, which advises variable, Its dosage, medicine advise that nomenclature of drug, medicine advise drug to add up daily dose, medicine advises drug integral dose, medicine that ingredient is advised to add up daily dose, medicine Advise ingredient integral dose, medicine advise drug minimum can divided dose, medicine advise the conventional dosage upper limit or lower limit and the Yao Zhu section of drug Room title.
It is preferably, described that share medicine to advise variable include sharing medicine to advise nomenclature of drug, share medicine and advise administration route, share medicine and advise Each dosage shares medicine and advises administration frequency, shares medicine and advise daily dosage and share Yao Zhu department title.
Preferably, the patient variables include patient age, weight, body surface area, diagnostic message, operation names, symptom, Medical history and allergies, pregnancy/lactation/puerpera's feature, complication and complication.
Preferably, the doctor's advice variable includes doctor's advice test rating title and test rating value, doctor's advice inspection item, doctor's advice Disease score project and disease score value.
Preferably, described to call corresponding judgment rule to specifically include in knowledge base according to the variable information:
Corresponding judgment rule is called in knowledge base according to the combination between the multiple variable information.
It is further preferred that whether the variable information judged after the assignment meets the judgment rule and specifically wraps It includes:
Based on the judgment rule of the calling, obtained in the knowledge base according to the multiple variable information corresponding Canonical variable range;
Whether the variable information after judging the assignment meets the canonical variable range.
A kind of generation method of medication information warning provided in an embodiment of the present invention, can be according to variable assignments method to patient Information extraction and assignment are carried out in essential information and the prescription/doctor's advice information, recalls judgment rule in knowledge base, are generated and are used Medicine information warning, to promote the accuracy of medication.
Detailed description of the invention
Fig. 1 is a kind of generation method flow chart of medication information warning provided in an embodiment of the present invention;
Fig. 2 is a kind of drug interaction judgment method flow chart provided in an embodiment of the present invention;
Fig. 3 is a kind of drug usage and dosage judgment method flow chart provided in an embodiment of the present invention.
Specific embodiment
Below by drawings and examples, technical scheme of the present invention will be described in further detail.
A kind of generation method of medication information warning provided in an embodiment of the present invention can be based on Prescription automatic screening system It realizes, Fig. 1 is a kind of generation method flow chart of medication information warning provided in an embodiment of the present invention, as shown in Figure 1, comprising:
Step 101, it is inserted into variable information;
System will first set the variable information of insertion before being inserted into variable information, be then inserted into, variable information packet Medicine is included to advise variable, share medicine and advise variable, patient variables and doctor's advice variable etc..
Medicine advises variable to can specifically include medicine administration route, medicine is advised to advise each dosage, medicine that administration frequency, medicine is advised to advise daily agent Amount, medicine advise nomenclature of drug, medicine that drug is advised to add up daily dose, medicine advise drug integral dose, medicine to advise ingredient adds up daily dose, medicine is advised into Point integral dose, medicine advise drug minimum can divided dose, medicine advise the conventional dosage upper limit or lower limit and Yao Zhu department name of drug Claim etc..
It shares medicine variable is advised to can specifically include and share medicine and advise nomenclature of drug, share medicine and advise administration route, share medicine and advise often Secondary dosage shares medicine and advises administration frequency, shares medicine and advise daily dosage and share Yao Zhu department title etc..
Patient variables can specifically include patient age, weight (birth weight, actual weight, ideal body weight, correction body Again), body surface area, diagnostic message, operation names, symptom, medical history and allergies, pregnancy/lactation/puerpera's feature, merging Disease and complication etc..
Doctor's advice variable can specifically include doctor's advice test rating title and test rating value, doctor's advice inspection item, doctor's advice disease Sick scoring item and disease score value etc..
It should be noted that variable information include but is not limited to above-mentioned medicine advise variable, share medicine advise variable, patient variables and One of doctor's advice variable is a variety of, and those skilled in the art, which can according to need, sets variable information.
Step 102, the patient ID and corresponding prescription/doctor's advice information of doctor's input are received;
Prescription/doctor's advice information is that doctor issues according to the case where each patient for it, that is to say, that doctor is for patient When the prescription and/or doctor's advice information issued, input patient ID is first had to, patient ID can be the identification card number of patient, then exist It may include above-mentioned variable letter in prescription/doctor's advice information according to being patient's prescription and/or doctor's advice information the case where patient One of breath is a variety of.
Step 103, the patient basis of patient is obtained according to patient ID;
Patient basis can specifically include patient age, weight (birth weight, actual weight, ideal body weight, correction Weight), body surface area, diagnostic message, operation names, symptom, medical history and allergies, pregnancy/lactation/puerpera's feature, close And disease and the information such as complication and the testing result of patient.
Step 104, it is obtained according to variable information to information extraction is carried out in patient basis and prescription/doctor's advice information The corresponding variate-value of variable information carries out assignment to corresponding variable information according to the variate-value extracted;
System carries out the information in patient basis and prescription/doctor's advice information according to the variable information being previously inserted Information extraction obtains the corresponding variate-value of one or more variable informations, assigns respectively to each variable information corresponding Variate-value.
Specifically, according to incoming patient medication information, triggering the judgement of knowledge base rule for medicine advises variable and patrolling Volume, determine that medicine advises nomenclature of drug, according to the name variable being inserted into the warning property frame of the knowledge base rule information warning of triggering, And the corresponding dictionary value of the drug that the corresponding patient medication information of the nomenclature of drug or knowledge base system are arranged, it assigns the medicine and advises The corresponding variate-value of drug.
It is advised for variable for sharing medicine, according to incoming patient medication information, triggers knowledge base rule decision logic, really Fixed this shares medicine and advises nomenclature of drug, according to the name variable being inserted into the knowledge base rule information warning property frame of triggering, assigns This shares medicine and advises the corresponding variate-value of drug.For example, the warning property frame insertion variable of triggering knowledge base rule information warning is Medicine advise drug minimum can divided dose trigger knowledge base rule decision logic, determine that the medicine is advised according to incoming patient medication information Nomenclature of drug is Nifedipine controlled-release tablet, then the minimum for the Nifedipine controlled-release tablet for taking system to be arranged can divided dose value 30mg.
For patient variables, according to incoming patient information, the warning content of knowledge base rule information warning is triggered The name variable of middle insertion assigns corresponding variate-value.
For doctor's advice variable, according to incoming patient's doctor's advice information, knowledge base rule decision logic is triggered, determining should Doctor's advice project name (such as test rating title, inspection item title, disease score project name) is advised according to the knowledge base of triggering The name variable being then inserted into information warning property frame assigns the medicine and advises the corresponding variate-value of drug.
Further, above-mentioned variable information can be divided into formula structure and non-formula structure, the variable information of formula structure Each dosage variation is advised including sub- variable information and operation rule, such as medicine, in insertion " medicine advises each dosage " variable, clicks insertion Variable will show all optional variables, and if medicine advises each dosage of per kilogram × actual weight product, medicine advises each agent of the every square meter of Amount × actual weight product, medicine advise each dosage of per kilogram × ideal body weight product, medicine to advise each dosage × correction of per kilogram Weight product etc.;Its Chinese medicine advises each dosage of per kilogram, medicine that each dosage of the every square meter of is advised to need editorial staff's maintenance is specific to use Pharmaceutical quantities, can be according to the dosage of maintenance and incoming patient's actual weight value or adjusted weight calculated value, ideal after the completion of maintenance The product of both weight value is calculated, and output end value is value.
In a specific example, it is 2 years old that patient age is recorded in patient basis, and weight 10kg is being cured Nomenclature of drug phenytoin sodium tablet is recorded in the raw prescription/doctor's advice issued, then in patient basis and prescription/doctor's advice information Information carries out information extraction, and obtained variable information has patient age, weight, medicine to advise nomenclature of drug, corresponding variate-value difference For 2 years old, 10kg, phenytoin sodium tablet, the variable information age is assigned a value of 2 years old, variable information weight is assigned a value of 10kg, variable information Medicine advises nomenclature of drug to be assigned a value of phenytoin sodium tablet.
Step 105, corresponding judgment rule is called in knowledge base according to variable information;
Corresponding judgment rule is called in knowledge base according to the combination between multiple variable informations, it is pre- in knowledge base The incidence relation being first equipped between multiple variable informations and judgment rule.
For example, then calling drug interaction to examine rule when containing two or more drugs in prescription.
Step 106, whether the variable information after judging assignment meets judgment rule;
Judgment rule based on calling obtains corresponding canonical variable according to the multiple variable information in knowledge base Range;Whether the variable information after judging assignment complies with standard range of variables.
When not meeting, step 107 is executed.When not meeting, without prompt.
Step 107, medication information warning is generated.
In a specific example, as shown in Fig. 2, each drug has corresponding judgment rule in knowledge base, For example recorded in interaction judgment rule, it is cut down containing atorvastatin, amlodipine besylate and atorvastatin calcium piece, atropic Prescription/doctor's advice of statin calcium capsule drug, if dry-mixed using gemfibrozil tablet, Fusidic Acid simultaneously in current prescriptions/doctor's advice Suspension, sodium fusidafe as injection, colchicines tablets, meet it is this under the conditions of, prompt doctor: [atorvastatin, ammonia chlorine Horizon atorvastatin, atorvastatin calcium capsule] and [gemfibrozil tablet, Fusidic Acid dry suspensoid agent, injection Fu Xi Ground acid sodium, colchicines tablets] drug combination when, Atorvastatin AUC is dramatically increased, and increases the risk of myopathy.It avoids sharing.
Here nomenclature of drug and to share nomenclature of drug be that variable in order to realize accurate prompt is inserted into two variables, are as follows: [medicine Advise drug title] with [share medicine and advise drug title] drug combination when, Atorvastatin AUC is dramatically increased, and increases myopathy Risk, avoid sharing.
Wherein, [medicine advises drug title] and [share medicine and advise drug title] is variable.
If doctor is that there are three drugs for the prescription issued of certain patient: atorvastatin, colchicines tablets, succinic acid Metoprolol tablets, atorvastatin, colchicines tablets, metroprolol succinate piece are respectively as [medicine advises drug title] [share medicine and advise drug title] is judged, is judged according to this knowledge rule, and [medicine advises drug title] variate-value is Atorvastatin, [share medicine and advise drug title] variate-value are colchicines tablets, then doctor terminal prompt information are as follows: atropic When cutting down statin calcium tablet and colchicines tablets drug combination, Atorvastatin AUC is dramatically increased, and increases the risk of myopathy, avoids closing With can accurately prompt doctor's any two drugs that cannot share compared with existing medical system, to keep doctor quick The drug that cannot be shared is adjusted.
Further, it can be seen from the above, variable information is formula structure or non-formula structure, the variable of two kinds of different structures The medication information warning that information generates is also different, therefore first determines whether variable information is formula structure, when variable information is When formula structure, the sub- variable information of variable information is obtained;It is counted according to the operation rule of sub- variable information and variable information It calculates, obtains medication information warning.
In another specific example, the place containing phenytoin sodium tablet is recorded as shown in figure 3, examining for dosage Side/doctor's advice judged, patient age < 14 years old, and daily administration dosage is not met within the scope of [3,8] mg/kg, prompts doctor: Daily dosage should be 3mg/kg [actual weight] -8mg/kg [actual weight].
Here, nomenclature of drug is variable, and infant weight is that variable is inserted into two variables, is to realize accurate prompt [medicine advises drug title] and [medicine advises the daily dosage of].Wherein [medicine advises the daily dosage of] has multiple formulas optional, in present case Selection medicine advises the daily dosage of per kilogram × actual weight product.
Information warning content are as follows: the infant uses [medicine advises drug title], and daily dosage should be 3mg/kg × practical body Weight -8mg/kg × actual weight.
If certain infant, weight 10kg, doctor issues phenytoin sodium tablet, daily dosage 100mg.It is advised according to this knowledge Then judge, which uses phenytoin sodium tablet, and daily dosage should be 30mg-80mg, 30mg-80mg canonical variable range, if The daily dosage of doctor terminal input not in this range, is then prompted.
A kind of generation method of medication information warning provided in an embodiment of the present invention, can be according to variable assignments method to patient Information extraction and assignment are carried out in essential information and the prescription/doctor's advice information, recalls judgment rule in knowledge base, are generated and are used Medicine information warning, to promote the accuracy of medication.
Professional should further appreciate that, described in conjunction with the examples disclosed in the embodiments of the present disclosure Unit and algorithm steps, can be realized with electronic hardware, computer software, or a combination of the two, hard in order to clearly demonstrate The interchangeability of part and software generally describes each exemplary composition and step according to function in the above description. These functions are implemented in hardware or software actually, the specific application and design constraint depending on technical solution. Professional technician can use different methods to achieve the described function each specific application, but this realization It should not be considered as beyond the scope of the present invention.
The step of method described in conjunction with the examples disclosed in this document or algorithm, can be executed with hardware, processor The combination of software module or the two is implemented.Software module can be placed in the random access memory (generation of RA medication information warning Method), the generation of memory, read-only memory (generation method of RO medication information warning), electrically programmable RO medication information warning Method, the generation method of electrically erasable RO medication information warning, register, hard disk, moveable magnetic disc, CD-RO medication In any other form of storage medium well known in the generation method or technical field of information warning.
Above-described specific embodiment has carried out further the purpose of the present invention, technical scheme and beneficial effects It is described in detail, it should be understood that being not intended to limit the present invention the foregoing is merely a specific embodiment of the invention Protection scope, all within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done should all include Within protection scope of the present invention.

Claims (8)

1. a kind of generation method of medication information warning, which is characterized in that the described method includes:
It is inserted into variable information;Wherein, the variable information includes that medicine advises variable, shares medicine variable, patient variables and doctor's advice is advised to become Amount;
Receive the patient ID and corresponding prescription/doctor's advice information of doctor's input;
The patient basis of patient is obtained according to the patient ID;
It is obtained according to the variable information to information extraction is carried out in the patient basis and the prescription/doctor's advice information The corresponding variate-value of the variable information;
Assignment is carried out to corresponding variable information according to the variate-value extracted;
Corresponding judgment rule is called in knowledge base according to the variable information;
Whether the variable information after judging the assignment meets the judgment rule;
When not meeting, medication information warning is generated.
2. the generation method of medication information warning according to claim 1, which is characterized in that the variable information is formula Structure or non-formula structure;The variable information of the formula structure includes sub- variable information and operation rule;The generation medication Information warning specifically includes:
Judge whether the variable information is formula structure;
When the variable information is formula structure, the sub- variable information of the variable information is obtained;
It is calculated according to the operation rule of the sub- variable information and the variable information, obtains the medication information warning.
3. the generation method of medication information warning according to claim 1, which is characterized in that it includes medicine that the medicine, which advises variable, Advise administration route, medicine that each dosage, medicine is advised to advise administration frequency, medicine that daily dosage, medicine is advised to advise nomenclature of drug, medicine that drug is advised to add up day Dosage, medicine advise that drug integral dose, medicine advise ingredient to add up daily dose, medicine advises ingredient integral dose, medicine to advise drug minimum that can divide agent Amount, medicine advise the conventional dosage upper limit or lower limit and Yao Zhu department title of drug.
4. the generation method of medication information warning according to claim 1, which is characterized in that the medicine that shares advises variable packet It includes and shares medicine and advise nomenclature of drug, share medicine and advise administration route, share medicine and advise each dosage, share medicine and advise administration frequency, share medicine It advises daily dosage and shares Yao Zhu department title.
5. the generation method of medication information warning according to claim 1, which is characterized in that the patient variables include suffering from Person's age, weight, body surface area, diagnostic message, operation names, symptom, medical history and allergies, pregnancy/lactation/puerpera are special Sign, complication and complication.
6. the generation method of medication information warning according to claim 1, which is characterized in that the doctor's advice variable includes doctor Advise test rating title and test rating value, doctor's advice inspection item, doctor's advice disease score project and disease score value.
7. the generation method of medication information warning according to claim 1, which is characterized in that described to be believed according to the variable Breath calls corresponding judgment rule to specifically include in knowledge base:
Corresponding judgment rule is called in knowledge base according to the combination between the multiple variable information.
8. the generation method of medication information warning according to claim 7, which is characterized in that after the judgement assignment Variable information whether meet the judgment rule and specifically include:
Based on the judgment rule of the calling, corresponding standard is obtained in the knowledge base according to the multiple variable information Range of variables;
Whether the variable information after judging the assignment meets the canonical variable range.
CN201910070383.2A 2019-01-18 2019-01-18 A kind of generation method of medication information warning Pending CN109817301A (en)

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CN111243750A (en) * 2020-01-15 2020-06-05 四川美康医药软件研究开发有限公司 Method and device for identifying pregnancy state of patient in multiple modes
CN111653371A (en) * 2020-06-05 2020-09-11 河南省药品评价中心 Early warning method for drug with potential addiction and hallucinogenic effect based on weighted judgment
CN111681777A (en) * 2020-06-05 2020-09-18 河南省药品评价中心 Early warning method of potential addiction-causing hallucinogenic drugs based on medical history information
CN112349371A (en) * 2020-11-18 2021-02-09 南通市第一人民医院 Chemotherapy patient drug record evaluation method and device

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CN112349371A (en) * 2020-11-18 2021-02-09 南通市第一人民医院 Chemotherapy patient drug record evaluation method and device

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Application publication date: 20190528