CN109794405A - High intensity focused ultrasound signal calibration circuit - Google Patents

High intensity focused ultrasound signal calibration circuit Download PDF

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CN109794405A
CN109794405A CN201910120209.4A CN201910120209A CN109794405A CN 109794405 A CN109794405 A CN 109794405A CN 201910120209 A CN201910120209 A CN 201910120209A CN 109794405 A CN109794405 A CN 109794405A
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resistance
signal
operational amplifier
triode
capacitor
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毕蓓蕾
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Abstract

The invention discloses high intensity focused ultrasound signal calibration circuits, the frequency modulation circuit receives the ultrasonic pulse frequency signal of ultrasonic power source output, enter after the oscillating circuit that triode Q1 is core is further modulated after frequency-selecting and exports, signal is also through successively calculating frequency offset signal after modulation, be converted to voltage signal, change varactor VD1 interelectrode capacity, adjust the frequency for the ultrasonic pulsative signal modulated again through oscillating circuit, enter range separation circuit later, it is the synchronizing separator circuit of core through triode Q2 and triode Q3, it is separated into the signal of two-way frequency same magnitude decaying 1/2, into amplitude regulating circuit, pass through operational amplifier AR2, operational amplifier AR3 is amplified, and change amplification factor by adjusting operational amplifier AR2/AR3 depth of feedback, most afterwards through transporting It is exported after calculating amplifier AR5 coupling superposition.The problem of frequency, the amplitude for the ultrasonic frequency signal that effective solution ultrasonic power source generates can deviate, not can guarantee precision.

Description

High intensity focused ultrasound signal calibration circuit
Technical field
The present invention relates to signal processing technology fields, more particularly to high intensity focused ultrasound signal calibration circuit.
Background technique
High intensity focused ultrasound technology is applied to medical domain non-invasive therapy tumour, principle are as follows: by high intensity focused ultrasound Energy centralization makes regional temperature moment be increased to 70 DEG C or more to diseased tissue area, and the histocyte in focal regions is caused to produce Raw coagulation necrosis, loses proliferation, infiltration and transfer ability.
High Intensity Focused Ultrasound system of tumor treatment includes ball-crown body, ultrasound power device and ultrasonic piezoelectric transducer at present, Ultrasound power device includes ultrasound emission controller and ultrasonic power source, and ultrasound emission controller is for controlling ultrasonic power source Pulse is sent, and ultrasonic power source is connected with ultrasonic piezoelectric transducer, and the transmitting of ultrasonic power source forcing ultrasonic piezoelectric transducer is certain The ultrasonic wave of dosage is focused on certain points of ball-crown body front end by the inner wall of ball-crown body, forms focal spot, and effect is reached with human body To the purpose for the treatment of.
The ultrasonic frequency signal for depending mainly on the size of ultrasonic power source output of dosage, and ultrasonic frequency signal is specifically By oscillating circuit in ultrasonic power source, power amplification circuit, energy converter match circuit alternating current it is converted Lai, by mains-supplied Power supply, circuit components parameter and transmission attenuation influence, and frequency, the amplitude of the ultrasonic frequency signal of generation can deviate, because It is to guarantee one of the important technological problems of therapeutic effect that this, which improves ultrasonic power source output ultrasonic frequency signal precision,.
So the present invention provides the new scheme of one kind to solve the problems, such as this.
Summary of the invention
For above situation, for the defect for overcoming the prior art, purpose of the present invention is to provide high intensity focused ultrasounds Signal calibration circuit, frequency, the amplitude for the ultrasonic frequency signal that effective solution ultrasonic power source generates can deviate, nothing Method guarantees the problem of precision.
Its technical solution solved is, including frequency modulation circuit, range separation circuit, amplitude regulating circuit, feature It is, the frequency modulation circuit receives the ultrasonic pulse frequency signal of ultrasonic power source output, through resistance R1- resistance R3, electricity The frequency selection circuit frequency-selecting for holding C1- capacitor C3 composition, filters out the signal other than ultrasonic pulse frequency signal, into operational amplifier The inverting input terminal of AR1 and the referenced ultrasound frequency signal subtraction of non-inverting input terminal export frequency offset signal, frequency offset signal warp The frequency-voltage conversion circuit output voltage signal that capacitor CR, inductance LR, inductance L2, resistance R4 are formed, causes varactor The variation of VD1 interelectrode capacity, and then adjust the ultrasonic frequency signal that the oscillating circuit that triode Q1 is core generates, the amplitude Split circuit receives the ultrasonic frequency signal of frequency modulation circuit output, divides through triode Q2 with triode Q3 for the synchronous of core From circuit, ultrasonic frequency signal is separated into the signal of two-way frequency same magnitude decaying 1/2, passes through the photoelectricity coupling of differential concatenation Whether the detection separation of clutch U1, U2 synchronizes, and exports low and high level driving triode Q4 on or off, triode Q2 and triode Q3 is that the synchronizing separator circuit of core resets, and is separated again to ultrasonic frequency signal, the amplitude regulating circuit is put by operation Big device AR2, operational amplifier AR3 respectively amplify signal after two-way separation, and wherein amplified signal is via operation amplifier Device AR6/ operational amplifier AR4 and 1/2 master output signal calculate amplitude difference, hinder between change metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source Value, and then operational amplifier AR2/AR3 depth of feedback is adjusted, change amplification factor, most couples and be superimposed through operational amplifier AR5 afterwards After export, with this solve the problems, such as adjust significantly signal accuracy it is low.
Due to the use of above technical scheme, the present invention has the following advantages that compared with prior art;
1, the ultrasonic pulse frequency signal of ultrasonic power source output filters out ultrasonic pulse frequency signal through frequency selection circuit frequency-selecting Signal other than 4MHz, the oscillating circuit formed into triode Q1, resistance R6- resistance R9, capacitor C4, capacitor C5, inductance L3 It is further exported after modulation, signal also calculates frequency offset signal through operational amplifier AR1 after modulation, frequency-voltage conversion circuit turns It is changed to voltage signal, this voltage causes the variation of varactor VD1 interelectrode capacity, and then adjusts and modulate again through oscillating circuit Ultrasonic pulsative signal frequency, to solve the problems, such as frequency deviation;
2, through modulated ultrasonic pulse frequency signal again through triode Q2 and triode Q3 be core synchronizing separator circuit, It is separated into the signal of two-way frequency same magnitude decaying 1/2, and is by photoelectrical coupler U1, U2 of differential concatenation detection separation No synchronization drives synchronizing separator circuit to reset when asynchronous, separates again to ultrasonic frequency signal;
Signal respectively enters in-phase proportion amplifier after separation and reverse phase proportional amplifier carries out ratio enlargement, and amplified signal is also Amplitude difference is calculated via operational amplifier AR6/ operational amplifier AR4 and 1/2 master output signal, through electrolytic capacitor E1/E2 After reverse phase, changes resistance value between metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source, and then adjust operational amplifier AR2/AR3 depth of feedback, change The amplification factor of operational amplifier AR2/ operational amplifier AR3 most exports after operational amplifier AR5 coupling superposition, afterwards with this Solve the problems, such as that ultrasonic pulse frequency signal amplitude degree of regulation direct greatly is low.
Detailed description of the invention
Fig. 1 is circuit module figure of the invention.
Fig. 2 is circuit diagram of the invention.
Fig. 3 is range separation circuit separation front and back comparison diagram of the invention.
Specific embodiment
For the present invention aforementioned and other technology contents, feature and effect, in following cooperation with reference to figures 1 through attached drawing 3 To in the detailed description of embodiment, can clearly present.The structure content being previously mentioned in following embodiment is with specification Attached drawing is reference.
Each exemplary embodiment of the invention is described below with reference to accompanying drawings.
Embodiment one, high intensity focused ultrasound signal calibration circuit, it is defeated that the frequency modulation circuit receives ultrasonic power source Ultrasonic pulse frequency signal out, the frequency selection circuit frequency-selecting formed through resistance R1- resistance R3, capacitor C1- capacitor C3, filters out ultrasound Signal other than pulse duration frequency signal 4MHz, into triode Q1, resistance R6- resistance R9, capacitor C4, capacitor C5, inductance L3 group At oscillating circuit further modulate after export, after modulation signal enter the inverting input terminal of operational amplifier AR1 with mutually defeated Enter the referenced ultrasound frequency signal subtraction at end, exports frequency offset signal, frequency offset signal is through capacitor CR, inductance LR, inductance L2, electricity The frequency-voltage conversion circuit output voltage signal of R4 composition is hindered, specific frequency offset signal is through capacitor CR, inductance LR, inductance L2 etc. Effect is a resistance value, and a voltage is generated after connecting with resistance R4, this voltage causes the change of varactor VD1 interelectrode capacity Change, and then adjust the frequency for the ultrasonic pulsative signal modulated again through oscillating circuit, to meet frequency accuracy requirement, solves frequency deviation The problem of, enter range separation circuit later, is the synchronizing separator circuit of core through triode Q2 and triode Q3, by supersonic frequency Rate Signal separator is the signal of two-way frequency same magnitude decaying 1/2, specific: such as model HY2900 focused ultrasound therapy system The ultrasonic frequency signal of 4MHz, 100V, 550W/cm2 of system ultrasonic power source output (since amplitude is big, pass through common amplification Device, triode, which are directly adjusted, is difficult to reach required precision, designs synchronizing separator circuit, and to the signal of amplitude fading 1/2, amplification is adjusted Coupled again after section, the precision of adjusting reached with this) the resistance R10 that is concatenated and the base that triode Q3 is added to after resistance R11 current limliting Pole, when being higher than the emitter voltage+50V of triode Q3, triode Q3 is in magnifying state, the ultrasound of+50V-+100V amplitude Frequency signal is separated, and similarly ultrasonic frequency signal is added to triode Q2 after diode D1 unilateal conduction, capacitor C6 coupling Base stage, when be lower than triode Q2 emitter voltage+50V when (by resistance R12, R 13, R14, resistance R15 and resistance R17 group At bleeder circuit provide), triode Q2 is in magnifying state, and the ultrasonic frequency signal of+0V-+50V amplitude is separated, i.e., + 0V-+100V ultrasonic frequency signal all the way is separated into the ultrasonic frequency signal that two-way frequency is identical, Magnitude Difference is 50V, The as signal of decaying 1/2, the signal in order to guarantee two-way frequency same magnitude decaying 1/2 after separating is synchronous, by reversely going here and there Photoelectrical coupler U1, U2 of connection are detected, and low and high level driving triode Q4 on or off, triode Q2 and three poles are exported Pipe Q3 is that the synchronizing separator circuit of core resets, and is separated again to ultrasonic frequency signal, the amplitude regulating circuit receives amplitude The signal of the two-way frequency same magnitude decaying 1/2 of split circuit output, respectively enters resistance R19, resistance R21, operation amplifier The reverse phase proportional amplifier that in-phase proportion amplifier and resistance R20, resistance R22, the operational amplifier AR3 of device AR2 composition are formed Ratio enlargement is carried out, amplified signal is also via operational amplifier AR6/ operational amplifier AR4 and 1/2 master output signal (tool Body with+50V-+100V ,+0V-+50V signal) carry out subtraction, amplitude difference is calculated, through electrolytic capacitor E1/E2 reverse phase Afterwards, resistance value between change metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source, and then operational amplifier AR2/AR3 depth of feedback is adjusted, change operation The amplification factor of amplifier AR2/ operational amplifier AR3, operational amplifier AR2/ operational amplifier AR3 amplified signal respectively into Enter the non-inverting input terminal and inverting input terminal of operational amplifier AR5, resistance is arranged in operational amplifier AR5 subtraction scale operation R27, resistance R26, resistance R24 resistance value are identical, and+0V-+100V the ultrasonic frequency signal after finally exporting amplitude modulation all the way is protected with this Demonstrate,prove the precision significantly adjusted.
Embodiment two, on the basis of example 1, the range separation circuit receive the super of frequency modulation circuit output Acoustic frequency signal is the synchronizing separator circuit of core through triode Q2 and triode Q3, ultrasonic frequency signal is separated into two-way The signal of frequency same magnitude decaying 1/2, it is specific: as model HY2900 focusing ultrasonic therapeutic system ultrasonic power source exports 4MHz, 100V, 550W/cm2 the resistance R10 that is concatenated of ultrasonic frequency signal and resistance R11 current limliting after be added to triode Q3 Base stage, when be higher than triode Q3 emitter voltage+50V when (by resistance R12, R 13, R14, resistance R15 and resistance R17 group At bleeder circuit provide), triode Q3 is in magnifying state, and the ultrasonic frequency signal of+50V-+100V amplitude is separated, Similarly ultrasonic frequency signal is added to the base stage of triode Q2 after diode D1 unilateal conduction, capacitor C6 coupling, when lower than three poles It (is mentioned by the bleeder circuit that resistance R12, R 13, R14, resistance R15 and resistance R17 are formed when the emitter voltage+50V of pipe Q2 For), triode Q2 is in magnifying state, and the ultrasonic frequency signal of+0V-+50V amplitude is separated, i.e., will+0V-+100V all the way Ultrasonic frequency signal is separated into the ultrasonic frequency signal that two-way frequency is identical, Magnitude Difference is 50V, is also the letter of decaying 1/2 Number, the signal in order to guarantee two-way frequency same magnitude decaying 1/2 after separating is synchronous, passes through the photoelectrical coupler of differential concatenation U1, U2 are detected, and specifically when two paths of signals is rising edge, photoelectrical coupler U1, U2 are not turned on, photoelectrical coupler The pin 4 of U1, U2 are high level, and triode Q4 conducting, it is core that ultrasonic frequency signal, which is transferred to triode Q2 and triode Q3, Synchronizing separator circuit normally separate, when two paths of signals one rising edge, one failing edge, photoelectrical coupler U1 or U2 conducting, The pin 4 of photoelectrical coupler U1, U2 are low level, triode Q4 cut-off, triode Q2 and synchronous point that triode Q3 is core From circuit reset, as capacitor C10 charges, triode Q4 conducting, synchronizing separator circuit again separates ultrasonic frequency signal, packet Triode Q4, the collector of the collector connecting triode Q1 of triode Q4 are included, the emitter of triode Q4 is separately connected two poles One end of the cathode of pipe D1, resistance R10, one end of the anode connection capacitor C6 of diode D1, the other end of capacitor C6 connect respectively One end of connecting resistance R12, one end of ground resistance R13, triode Q2 base stage, the emitter of triode Q2 is separately connected resistance One end of R15, the emitter of triode Q3, one end of ground resistance R17, resistance R12 the other end, the other end of resistance R10 Be separately connected one end of resistance R11, the other end of resistance R15, one end of resistance R14, capacitor C8 one end, resistance R14's is another One end connects power supply+100V, the base stage of the other end connecting triode Q3 of resistance R11, the other end connecting triode of capacitor C8 The collector of Q3, the pin 1 of photoelectrical coupler U1, photoelectrical coupler U2 pin 2, the collector of triode Q2, which is separately connected, to be connect One end of ground resistance R16, capacitor C7 one end, the other end of capacitor C7 is separately connected the pin 2 of photoelectrical coupler U1, photoelectricity coupling The pin 1 of clutch U2, the pin 3 of photoelectrical coupler U1 and the pin 3 of photoelectrical coupler U2 are all connected with ground, photoelectrical coupler U1's Pin 4 is separately connected the base of the pin 4 of photoelectrical coupler U2, one end of resistance R18, one end of ground capacity C10, triode Q4 The other end of pole, resistance R18 connects power supply+6V;
The amplitude regulating circuit receives the signal of the two-way frequency same magnitude decaying 1/2 of range separation circuit output, respectively It is put into resistance R19, resistance R21, the in-phase proportion amplifier of operational amplifier AR2 composition and resistance R20, resistance R22, operation The reverse phase proportional amplifier of big device AR3 composition carries out ratio enlargement, wherein the adjustable ratio of the resistance value for adjusting feedback resistance R21, R22 Example amplification multiple, capacitor C9 connect operational amplifier AR2 non-inverting input terminal and operational amplifier AR3 inverting input terminal it Between, to avoid crosstalk between two paths of signals, amplified signal is also marked via operational amplifier AR6/ operational amplifier AR4 and 1/2 Quasi- range signal (specifically with+50V-+100V ,+0V-+50V signal) carries out subtraction, amplitude difference is calculated, through electrolysis electricity After holding E1/E2 reverse phase, change resistance value between metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source, and then it is deep to adjust operational amplifier AR2/AR3 feedback Degree changes the amplification factor of operational amplifier AR2/ operational amplifier AR3, operational amplifier AR2/ operational amplifier AR3 amplification Signal respectively enters the non-inverting input terminal and inverting input terminal of operational amplifier AR5, operational amplifier AR5 subtraction ratio fortune afterwards It calculates, setting resistance R27, resistance R26, resistance R24 resistance value are identical ,+0V-+100V the supersonic frequency after finally exporting amplitude modulation all the way Signal, solving the problems, such as adjusting with this, significantly signal accuracy is low, including resistance R19, resistance R20, one end connection of resistance R19 The collector of triode Q3, the other end of resistance R19 are separately connected the homophase input of one end of capacitor C9, operational amplifier AR2 End, one end of the inverting input terminal connection resistance R21 of operational amplifier AR2, the other end of resistance R21 are separately connected operation amplifier The output end of device AR2, the non-inverting input terminal of operational amplifier AR6, resistance R26 one end, the anti-phase input of operational amplifier AR6 End is separately connected one end of one end of resistance R28, resistance R29, and the other end of resistance R29 is same mutually defeated with operational amplifier AR4's Enter 1/2 master output signal of end connection, the output end of operational amplifier AR6 is separately connected the other end of resistance R28, electrolytic capacitor The grid of the cathode of E1, metal-oxide-semiconductor T1, the anode of electrolytic capacitor E1, the source electrode of metal-oxide-semiconductor T1 connect ground, the drain electrode connection of metal-oxide-semiconductor T1 The non-inverting input terminal of operational amplifier AR2, the other end of resistance R26 are separately connected the non-inverting input terminal of operational amplifier AR5, electricity One end of R27 is hindered, the other end of resistance R20 is separately connected the inverting input terminal of the other end of capacitor C9, operational amplifier AR3, One end of non-inverting input terminal connection resistance R22 of operational amplifier AR3, the other end of resistance R22 are separately connected operational amplifier The output end of AR3, one end of resistance R24, one end of resistance R23, operational amplifier AR4 inverting input terminal, operational amplifier The output end of AR4 is separately connected the grid of the other end of resistance R23, the cathode of electrolytic capacitor E2, metal-oxide-semiconductor T2, electrolytic capacitor E2 Anode, metal-oxide-semiconductor T2 source electrode connect ground, metal-oxide-semiconductor T2 drain electrode connection operational amplifier AR3 inverting input terminal, resistance R24 The other end be separately connected the inverting input terminal of one end of ground resistance R25, operational amplifier AR5, operational amplifier AR5's is defeated Outlet is separately connected one end of the other end of resistance R27, resistance R30, and the other end of resistance R30 is the output of amplitude regulating circuit Signal.
Embodiment three, on the basis of example 2, the frequency modulation circuit receive ultrasonic power source (such as model The ultrasonic frequency signal of 4MHz, 100V, 550W/cm2 of the output of HY2900 focusing ultrasonic therapeutic system ultrasonic power source) output Ultrasonic pulse frequency signal, the frequency selection circuit frequency-selecting formed through resistance R1- resistance R3, capacitor C1- capacitor C3, filters out ultrasonic pulse Signal other than frequency signal 4MHz is formed into triode Q1, resistance R6- resistance R9, capacitor C4, capacitor C5, inductance L3 Oscillating circuit exports after further modulating, and signal enters the inverting input terminal and non-inverting input terminal of operational amplifier AR1 after modulation Referenced ultrasound frequency signal subtraction (can be provided) by oscillograph, export frequency offset signal, frequency offset signal is through capacitor CR, inductance The frequency-voltage conversion circuit output voltage signal that LR, inductance L2, resistance R4 are formed, specific frequency offset signal is through capacitor CR, electricity Sense LR, inductance L2 are equivalent to a resistance value, and a voltage is generated after connecting with resistance R4, this voltage causes varactor The variation of VD1 interelectrode capacity, and then the frequency for the ultrasonic pulsative signal modulated again through oscillating circuit is adjusted, to meet frequency essence Degree requires, and solves the problems, such as frequency deviation, including resistance R1, capacitor C1, one end of resistance R1, one end of capacitor C1 are all connected with ultrasonic function Rate source output signal, the other end of resistance R1 are separately connected one end of one end of resistance R3, ground capacity C2, and capacitor C1's is another End is separately connected one end of one end of capacitor C3, ground resistance R2, and the other end of resistance R3 and the other end of capacitor C3 are all connected with The other end of inductance LR, one end of resistance R4, one end of resistance R6, the base stage of triode Q1, one end of inductance L2, two pole of transfiguration The other end of one end of the anode of pipe DC1, variable capacitance C4, resistance R4 connects power supply+5V, the other end of inductance L2, transfiguration two The cathode of pole pipe DC1, the other end of variable capacitance C4 be all connected with ground, the emitter of triode Q1 by resistance R8 connection, three The collector of pole pipe Q1 be separately connected the other end of resistance R6, one end of resistance R7, one end of inductance L1, capacitor C5 one end, One end of ground resistance R9, the cathode of voltage-stabiliser tube Z1, operational amplifier AR1 inverting input terminal, voltage-stabiliser tube Z1 anode connection Ground, the other end of resistance R7 are separately connected the other end of the other end of inductance L3, one end of resistance R31, capacitor C5, resistance R31 The other end connect power supply+5V, operational amplifier AR1 non-inverting input terminal connection benchmark have children outside the state plan frequency signal, operational amplifier One end of the output end connection capacitor CR of AR1, one end of the other end connection inductance LR of capacitor CR.
When the present invention is specifically used, the frequency modulation circuit receives the ultrasonic pulse frequency letter of ultrasonic power source output Number, through resistance R1- resistance R3, capacitor C1- capacitor C3 form frequency selection circuit frequency-selecting, filter out ultrasonic pulse frequency signal 4MHz with Outer signal, it is further into triode Q1, resistance R6- resistance R9, capacitor C4, capacitor C5, the oscillating circuit of inductance L3 composition It is exported after modulation, signal enters the inverting input terminal of operational amplifier AR1 and the referenced ultrasound frequency of non-inverting input terminal after modulation Signal (can be provided) subtraction by oscillograph, export frequency offset signal, frequency offset signal is through capacitor CR, inductance LR, inductance L2, resistance The frequency-voltage conversion circuit output voltage signal of R4 composition, specific frequency offset signal are equivalent through capacitor CR, inductance LR, inductance L2 For a resistance value, a voltage is generated after connecting with resistance R4, this voltage causes the change of varactor VD1 interelectrode capacity Change, and then adjust the frequency for the ultrasonic pulsative signal modulated again through oscillating circuit, to meet frequency accuracy requirement, solves frequency deviation The problem of, enter range separation circuit later, is the synchronizing separator circuit of core through triode Q2 and triode Q3, by supersonic frequency Rate Signal separator is the signal of two-way frequency same magnitude decaying 1/2, specific: such as model HY2900 focused ultrasound therapy system The resistance R10 and resistance R11 limit that the ultrasonic frequency signal of 4MHz, 100V, 550W/cm2 of system ultrasonic power source output are concatenated The base stage of triode Q3 is added to after stream, when being higher than the emitter voltage+50V of triode Q3, triode Q3 is in magnifying state, The ultrasonic frequency signal of+50V-+100V amplitude is separated, and similarly ultrasonic frequency signal is through diode D1 unilateal conduction, capacitor Be added to the base stage of triode Q2 after C6 coupling, when being lower than the emitter voltage+50V of triode Q2 (by resistance R12, R 13, The bleeder circuit of R14, resistance R15 and resistance R17 composition provides), triode Q2 is in magnifying state, and+0V-+50V amplitude surpasses Acoustic frequency Signal separator comes out, i.e., will be separated into that two-way frequency is identical, Magnitude Difference is by+0V-+100V ultrasonic frequency signal all the way The ultrasonic frequency signal of 50V is also the signal of decaying 1/2, in order to guarantee two-way frequency same magnitude decaying 1/2 after separating Signal is synchronous, is detected by photoelectrical coupler U1, U2 of differential concatenation, specifically when two paths of signals is rising edge, Photoelectrical coupler U1, U2 are not turned on, and the pin 4 of photoelectrical coupler U1, U2 are high level, triode Q4 conducting, supersonic frequency Signal is transferred to the synchronizing separator circuit that triode Q2 and triode Q3 is core and normally separates, when one rising edge of two paths of signals When one failing edge, photoelectrical coupler U1 or U2 conducting, the pin 4 of photoelectrical coupler U1, U2 are low level, and triode Q4 is cut Only, triode Q2 and triode Q3 is that the synchronizing separator circuit of core resets, as capacitor C10 charges, triode Q4 conducting, together It walks split circuit again to separate ultrasonic frequency signal, avoids dividing caused by triode Q2 and triode Q3 non_uniform response with this From nonsynchronous problem, the amplitude regulating circuit receives the two-way frequency same magnitude decaying 1/2 of range separation circuit output Signal, respectively enter resistance R19, resistance R21, operational amplifier AR2 composition in-phase proportion amplifier and resistance R20, electricity The reverse phase proportional amplifier for hindering R22, operational amplifier AR3 composition carries out ratio enlargement, wherein adjusting feedback resistance R21, R22 The multiple of resistance value adjustable proportion amplification, capacitor C9 connect the non-inverting input terminal and operational amplifier AR3 in operational amplifier AR2 Between inverting input terminal, to avoid crosstalk between two paths of signals, amplified signal is also via operational amplifier AR6/ operation amplifier Device AR4 and 1/2 master output signal (specifically with+50V-+100V ,+0V-+50V signal) carry out subtraction, calculate width It is poor to spend, and after electrolytic capacitor E1/E2 reverse phase, changes resistance value between metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source, and then adjust operational amplifier AR2/AR3 depth of feedback changes the amplification factor of operational amplifier AR2/ operational amplifier AR3, operational amplifier AR2/ operation Amplifier AR3 amplified signal respectively enters the non-inverting input terminal and inverting input terminal of operational amplifier AR5, operational amplifier AR5 subtraction scale operation, setting resistance R27, resistance R26, resistance R24 resistance value are identical ,+the 0V-+ after finally exporting amplitude modulation all the way It is low to solve the problems, such as to adjust significantly signal accuracy with this for the ultrasonic pulse frequency signal of 100V, 4MHz.

Claims (3)

1. high intensity focused ultrasound signal calibration circuit, including frequency modulation circuit, range separation circuit, amplitude regulating circuit, It is characterized in that, the frequency modulation circuit receives the ultrasonic pulse frequency signal of ultrasonic power source output, through resistance R1- resistance The frequency selection circuit frequency-selecting of R3, capacitor C1- capacitor C3 composition, filters out the signal other than ultrasonic pulse frequency signal, into triode Q1 be core oscillating circuit further modulate after export, after modulation signal enter operational amplifier AR1 inverting input terminal and The referenced ultrasound frequency signal subtraction of non-inverting input terminal exports frequency offset signal, and frequency offset signal is through capacitor CR, inductance LR, electricity The frequency-voltage conversion circuit output voltage signal for feeling L2, resistance R4 composition, causes the change of varactor VD1 interelectrode capacity Change, and then adjusts the ultrasonic pulse frequency signal that the oscillating circuit that triode Q1 is core generates, the amplitude separation electricity Road receives the ultrasonic frequency signal of frequency modulation circuit output, through the separated in synchronization electricity that triode Q2 and triode Q3 is core Ultrasonic frequency signal is separated into the signal of two-way frequency same magnitude decaying 1/2, passes through the photoelectrical coupler of differential concatenation by road Whether U1, U2 detection separation synchronize, and export low and high level driving triode Q4 on or off, triode Q2 and triode Q3 are The synchronizing separator circuit of core resets, and separates again to ultrasonic frequency signal, and the amplitude regulating circuit passes through operational amplifier AR2, operational amplifier AR3 respectively amplify signal after two-way separation, and wherein amplified signal is via operational amplifier AR6/ operational amplifier AR4 and 1/2 master output signal calculate amplitude difference, hinder between change metal-oxide-semiconductor T1/ metal-oxide-semiconductor T2 drain-source Value, and then operational amplifier AR2/AR3 depth of feedback is adjusted, change amplification factor, most couples and be superimposed through operational amplifier AR5 afterwards After export, with this solve the problems, such as adjust significantly signal accuracy it is low.
2. high intensity focused ultrasound signal calibration circuit as described in claim 1, which is characterized in that including triode Q4, three The collector of the collector connecting triode Q1 of pole pipe Q4, the emitter of triode Q4 are separately connected the cathode of diode D1, electricity One end of R10, one end of the anode connection capacitor C6 of diode D1 are hindered, the other end of capacitor C6 is separately connected the one of resistance R12 End, one end of ground resistance R13, triode Q2 base stage, the emitter of triode Q2 is separately connected one end of resistance R15, three The emitter of pole pipe Q3, one end of ground resistance R17, resistance R12 the other end, the other end of resistance R10 is separately connected resistance One end of R11, the other end of resistance R15, one end of resistance R14, capacitor C8 one end, resistance R14 the other end connection power supply+ The base stage of the other end connecting triode Q3 of 100V, resistance R11, collector, the light of the other end connecting triode Q3 of capacitor C8 The pin 2 of the pin 1 of electric coupler U1, photoelectrical coupler U2, the collector of triode Q2 are separately connected the one of ground resistance R16 It holds, one end of capacitor C7, the other end of capacitor C7 is separately connected the pin of the pin 2 of photoelectrical coupler U1, photoelectrical coupler U2 The pin 3 of 1, photoelectrical coupler U1 and the pin 3 of photoelectrical coupler U2 are all connected with ground, and the pin 4 of photoelectrical coupler U1 connects respectively Meet the base stage of the pin 4 of photoelectrical coupler U2, one end of resistance R18, one end of ground capacity C10, triode Q4, resistance R18 The other end connect power supply+6V;
The amplitude regulating circuit includes resistance R19, resistance R20, the collector of one end connecting triode Q3 of resistance R19, electricity The other end of resistance R19 is separately connected the non-inverting input terminal of one end of capacitor C9, operational amplifier AR2, and operational amplifier AR2's is anti- Phase input terminal connects one end of resistance R21, and the other end of resistance R21 is separately connected the output end of operational amplifier AR2, operation is put One end of the non-inverting input terminal of big device AR6, resistance R26, the inverting input terminal of operational amplifier AR6 are separately connected resistance R28's One end, resistance R29 one end, the other end of resistance R29 connects 1/2 master output with the non-inverting input terminal of operational amplifier AR4 Signal, the output end of operational amplifier AR6 are separately connected the other end of resistance R28, the cathode of electrolytic capacitor E1, metal-oxide-semiconductor T1 Grid, the anode of electrolytic capacitor E1, the source electrode of metal-oxide-semiconductor T1 connect ground, and the drain electrode connection operational amplifier AR2's of metal-oxide-semiconductor T1 is same Phase input terminal, the other end of resistance R26 are separately connected one end of the non-inverting input terminal of operational amplifier AR5, resistance R27, resistance The other end of R20 is separately connected the inverting input terminal of the other end of capacitor C9, operational amplifier AR3, and operational amplifier AR3's is same One end of phase input terminal connection resistance R22, the other end of resistance R22 are separately connected the output end of operational amplifier AR3, resistance One end of R24, one end of resistance R23, operational amplifier AR4 inverting input terminal, the output end of operational amplifier AR4 connects respectively The other end of connecting resistance R23, the cathode of electrolytic capacitor E2, metal-oxide-semiconductor T2 grid, the source of the anode of electrolytic capacitor E2, metal-oxide-semiconductor T2 Pole connection ground, the inverting input terminal of the drain electrode connection operational amplifier AR3 of metal-oxide-semiconductor T2, the other end of resistance R24, which is separately connected, to be connect One end of ground resistance R25, operational amplifier AR5 inverting input terminal, the output end of operational amplifier AR5 is separately connected resistance One end of the other end of R27, resistance R30, the other end of resistance R30 are the output signal of amplitude regulating circuit.
3. high intensity focused ultrasound signal calibration circuit as described in claim 1, which is characterized in that the frequency modulation circuit Including resistance R1, capacitor C1, one end of resistance R1, one end of capacitor C1 are all connected with ultrasonic power source output signal, resistance R1's The other end is separately connected one end of one end of resistance R3, ground capacity C2, and the other end of capacitor C1 is separately connected the one of capacitor C3 It holds, one end of ground resistance R2, the other end of resistance R3 and the other end of capacitor C3 are all connected with the other end of inductance LR, resistance R4 One end, one end of resistance R6, the base stage of triode Q1, one end of inductance L2, varactor DC1 anode, variable capacitance One end of C4, the other end of resistance R4 connect power supply+5V, the other end of inductance L2, varactor DC1 cathode, can power transformation The other end for holding C4 is all connected with ground, and by resistance R8 connection, the collector of triode Q1 connects the emitter of triode Q1 respectively The other end of connecting resistance R6, one end of resistance R7, one end of inductance L1, one end of capacitor C5, one end of ground resistance R9, pressure stabilizing The inverting input terminal of the cathode of pipe Z1, operational amplifier AR1, the anode connection ground of voltage-stabiliser tube Z1, the other end difference of resistance R7 The other end of the other end of inductance L3, one end of resistance R31, capacitor C5 are connected, the other end of resistance R31 connects power supply+5V, fortune The non-inverting input terminal connection benchmark for calculating amplifier AR1 has children outside the state plan frequency signal, the output end connection capacitor CR's of operational amplifier AR1 One end, one end of the other end connection inductance LR of capacitor CR.
CN201910120209.4A 2019-02-18 2019-02-18 High intensity focused ultrasound signal calibration circuit Pending CN109794405A (en)

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