Summary of the invention
Based on this, it is necessary in view of the above-mentioned problems, providing a kind of data fusion method, device, computer equipment and readable
Storage medium.
A kind of data fusion method, comprising:
It is registrated the function image of target object and the anatomic image of the target object, obtains registration result;
According to the anatomic image, first object image and the second target image are obtained, wherein the second target figure
Include blood vessel as in, includes remaining organ in the first object image;
Determine mapping data of the functional parameter on the outer profile for the remaining organ that the first object image includes;
Wherein, the functional parameter is used to characterize the activity situation of residue organ described in the registration result;
According to the mapping data, the outer profile image of the remaining organ is obtained;
According to second target image, analogue data is obtained, wherein the analogue data characterization parameter preset is described
Distribution situation in blood vessel;
Merge the outer profile image and the analogue data.
It is described according to second target image in one of the embodiments, obtain analogue data, comprising:
According to second target image, the second target simulation model is constructed;
According to the second target simulation model, computational fluid dynamics analogue simulation is carried out, the analogue data is obtained.
The remaining organ that the determining functional parameter includes in the first object image in one of the embodiments,
Mapping data on outer profile, comprising:
Determine the central point of the remaining organ;
Obtain the central point to the remaining organ outer profile ray;
The function image and the ray for including according to the registration result, determine functional parameter set, described
The parameter that functional parameter set includes is part corresponding parameter of the ray by the remaining organ;
According to the functional parameter set, the mapping data are determined.
It is described in one of the embodiments, to obtain the outer profile image of the remaining organ according to the mapping data,
Include:
Determine the intersection point of the ray Yu the outer profile;
The mapping data are mapped to the intersection point;
The outer profile image of the remaining organ is obtained according to the intersection point.
The remaining organ that the determining functional parameter includes in the first object image in one of the embodiments,
Mapping data on outer profile, comprising:
Determine the central axes of the remaining organ;
According to first point on the outer profile, determined on the central axes apart from described first point nearest second
Point, described first point is any point on the outer profile;
It obtains and connects first point of target segment between the second point;
The function image for including according to the registration result and the target segment, determine functional parameter set,
The parameter that the functional parameter set includes is part corresponding parameter of the target segment by the remaining organ;
According to the functional parameter set, the mapping data are determined.
It is described in one of the embodiments, to obtain the outer profile image of the remaining organ according to the mapping data,
Include:
The mapping data are mapped at described first point;
The outer profile image of the remaining organ is obtained according to described first point.
It is described according to the functional parameter set in one of the embodiments, determine the mapping data, comprising:
Maximum value is determined from the functional parameter that the functional parameter set includes, and the maximum value is reflected as described in
Penetrate data;
Alternatively,
The average value for determining the functional parameter that the functional parameter set includes, using the average value as the mapping number
According to;
Alternatively,
The integrated value for determining the functional parameter that the functional parameter set includes, using the integrated value as the mapping number
According to.
A kind of data fusion device, comprising:
Registration module is registrated for being registrated the function image of target object and the anatomic image of the target object
As a result;
Processing module, for obtaining first object image and the second target image according to the anatomic image, wherein
Include blood vessel in second target image, includes remaining organ in the first object image;
Determining module, for determining functional parameter on the outer profile for the remaining organ that the first object image includes
Map data;Wherein, the functional parameter is used to characterize the activity situation of residue organ described in the registration result;
Outer profile image obtains module, for obtaining the outer profile image of the remaining organ according to the mapping data;
Analogue data obtains module, for obtaining analogue data, wherein the simulation according to second target image
Distribution situation of the data characterization parameter preset in the blood vessel;
Fusion Module, for merging the outer profile image and the analogue data.
A kind of computer equipment, including memory and processor, the memory are stored with computer program, the processing
The step of device realizes method as described above when executing the computer program.
A kind of computer readable storage medium, is stored thereon with computer program, and the computer program is held by processor
The step of method as described above is realized when row.
The data fusion method, device, computer equipment and readable storage medium storing program for executing provided by the embodiments of the present application, pass through
It is registrated the function image of target object and the anatomic image of the target object, obtains registration result, and according to the internal anatomy
Picture obtains first object image and the second target image.Then determine that functional parameter includes in the first object image
Mapping data on the outer profile of the residue organ obtain the outer profile figure of the remaining organ according to the mapping data
Picture.Meanwhile according to second target image, analogue data is obtained.Finally merge the outer profile image and the simulation number
According to.The data fusion method, device, computer equipment and readable storage medium storing program for executing provided by the embodiments of the present application can be with described
The function image and the anatomic image of target object are input, obtain the outer profile image comprising functional parameter
With the analogue data, the outer profile image and the analogue data are merged, so that both including in obtained image
Functional parameter, and analogue data is contained, it allows users to intuitively obtain lesion vessels and its remaining organ dominated
Corresponding relationship improve assessment efficiency and effect and from the severity of multi-angle assessment lesion.
Specific embodiment
Data fusion method provided by the present application can be adapted for computer equipment shown in FIG. 1, the computer equipment packet
Include processor, memory, network interface and the database connected by system bus.Wherein, the processor of the computer equipment
For providing calculating and control ability.The memory of the computer equipment includes non-volatile memory medium, built-in storage.This is non-
Volatile storage medium is stored with operating system, computer program and database.The built-in storage is non-volatile memory medium
In operating system and computer program operation provide environment.The database of the computer equipment is for storing the application implementation
Video file etc. in example.The network interface of the computer equipment is used to communicate with external terminal by network connection.It is optional
, which can be server, can be PC, can also be personal digital assistant, can also be other terminals
Equipment, such as PAD, mobile phone etc. can also be cloud or remote server, tool of the embodiment of the present application to computer equipment
Body form and without limitation.
In order to which the objects, technical solutions and advantages of the application are more clearly understood, pass through following embodiments and combine attached
Figure, the further description of technical solutions in the embodiments of the present application.It should be appreciated that specific embodiment described herein
Only to explain the application, it is not used to limit application.
The data fusion method provided by the embodiments of the present application can be applied to the processing to medical domain image data.
Mainly by the Medical image fusion and processing to human body or animal organ or tissue, the function of further reaction member or tissue
Energy situation, and then doctor is assisted to make more reasonable diagnosis.
Fig. 2 is referred to, the application one embodiment provides a kind of data fusion method, which comprises
S10 is registrated the function image of target object and the anatomic image of the target object, obtains registration result.Wherein,
It include the target object in the function image and the anatomic image.
The target object refers to the organ or tissue for needing to assess and understand function.For example, the target object can be with
It is heart, brain, liver etc..
The function image is the image for referring to reflect from microcirculation level the functional parameter of the target object.It is described
The acquisition of function image includes but is not limited to PET, SPET (single photon emission tomography, single photon hair
Penetrate body section radiography), CT perfusion, MR perfusion etc..The function image can be 3D rendering.The function image can be 1 width,
It may be several, i.e., the described function image can be the image sequence of the characterization a certain functional parameter of target object.
The anatomic image is the image for referring to reflect from morphology level the anatomic form of the target object.It is described
The acquisition of anatomic image includes but is not limited to CT, MR etc..The anatomic image can be 3D rendering.
The function image comprising the target object and the target object are registrated, this Shen of the method for registration
It please be not specifically limited, can be selected according to actual needs.Being registrated the obtained registration result includes the functional diagram
Functional parameter as in also comprising the anatomic form in the anatomic image, therefore can intuitively reflect the target pair
The morphology lesion and function lesion of elephant.
S20 obtains first object image and the second target image according to the anatomic image.Wherein, second mesh
It include blood vessel in logo image.It include remaining organ in the first object image.The blood vessel in second target image
For for the remaining organ service in the first object.
Specifically, handling the anatomic image, the target object in the anatomic image is divided into institute
Blood vessel and the remaining organ are stated, the first object image and second target image are obtained.The residue organ refers to
The target object removes the part of the blood vessel.For example, the target object is heart.At the anatomic image of heart
Reason, obtains heart chamber figure and coronary artery figure, the as described first object image and second target image.
S30 determines mapping of the functional parameter on the outer profile for the remaining organ that the first object image includes
Data.Wherein, the functional parameter is used to characterize the activity situation of residue organ described in the registration result.
It is input with the registration result and the first object image, by the functional parameter in the registration result
With the corresponding relationship of the outer profile of residue organ described in the first object image.The mapping data characterize the function
The corresponding relationship of the outer profile of parameter and the remaining organ.It include the functional parameter in the registration result, therefore, according to
The registration result and the first object image, obtain the mapping data.
S40 obtains the outer profile image of the remaining organ according to the mapping data.
That is, according to the corresponding relationship of the functional parameter and the outer profile of the remaining organ, by the function
Parameter is mapped in the outer profile image of the remaining organ, so that containing in the outer profile of the residue organ
The functional parameter.The functional parameter can be intuitively obtained by the outer profile image.
S50 obtains analogue data according to second target image, wherein the analogue data characterization parameter preset exists
Distribution situation in the blood vessel.
Based on the anatomic image of the blood vessel, the threedimensional model of the blood vessel is constructed, and simulates and obtains parameter preset in institute
State the distribution situation in blood vessel.The parameter preset can be one of hemodynamic parameter or a variety of.The simulation number
According to the situation that can embody the blood vessel.Obtain mode the application of the analogue data without limitation, it can be according to practical need
Ask selection.
S60 merges the outer profile image and the analogue data.
Specifically, the outer profile image and the analogue data can be overlapped, fusion figure is formed.The application couple
Merge the method for superposition without limitation.Include the functional parameter of the target object in the fusion figure, also includes described
The analogue data of target object.
In the present embodiment, by being registrated the function image of target object and the anatomic image of the target object, matched
Standard is as a result, and according to the anatomic image, acquisition first object image and the second target image.Then determine that functional parameter exists
Mapping data on the outer profile for the remaining organ that the first object image includes are obtained according to the mapping data
The outer profile image of the residue organ.Meanwhile according to second target image, analogue data is obtained.Finally described in fusion
Outer profile image and the analogue data.The method provided by the embodiments of the present application can be with the function of the target object
Energy image and the anatomic image are input, obtain the outer profile image comprising functional parameter and the analogue data,
The outer profile image and the analogue data are merged, so that not only including functional parameter in obtained image, but also packet
Contained analogue data, allow users to intuitively obtain lesion vessels and its dominate remaining organ corresponding relationship, and from
Multi-angle assesses the severity of lesion, improves assessment efficiency and effect.
Fig. 3 is referred to, in one embodiment, S50 includes:
S510 constructs the second target simulation model according to second target image;
S520 carries out computational fluid dynamics analogue simulation, obtains the simulation according to the second target simulation model
Data.
Based on second target image that the blood vessel segmentation obtains, 3D solving model, as described second mesh are constructed
Mark simulation model.According to second simulation model, computational fluid dynamics (CFD, Computational Fluid is carried out
Dynamics) analogue simulation.According to simulation results, distribution of the intravascular parameter preset in the blood vessel is obtained
Situation.The parameter preset can include but is not limited to as FFR (Fractional Flow Reserve, coronary flow storage
Back-up number), wall shear stress (WWS), blood flow pressure, blood flow velocity etc..Based on the anatomic image (such as magnetic resonance radiography figure
Picture) it is split and obtains blood vessel result (such as blood vessel mask), institute is then obtained according to the grid that segmentation result constructs blood vessel
The second target simulation model is stated, determines blood flow import and export boundary condition by calculating stream according to the second target simulation model
Mechanics carry out analogue simulation to the blood flow of blood vessel and obtain analog result.
In the present embodiment, according to second target image, the second target simulation model is constructed, and according to second mesh
Simulation model is marked, carries out calculating Hydrodynamics Simulation simulation, obtains the analogue data.The method provided in this embodiment obtains
The method for taking the analogue data is simple and effective, ensure that speed and accuracy rate that the analogue data obtains.
Fig. 4 is referred to, in one embodiment, S30 includes:
S310A determines the central point of the remaining organ;
S320A, obtain the central point to the remaining organ outer profile ray;
S330A, the function image and the ray for including according to the registration result, determines functional parameter collection
It closes, the parameter that the functional parameter set includes is part corresponding parameter of the ray by the remaining organ;
S340A determines the mapping data according to the functional parameter set.
In second target image, emit from the central point of the remaining organ to the outer profile of the remaining organ
Ray.Based on the pass corresponding with organ described in the registration result image of residue organ described in second target image
System, obtains the data point that the ray passes through functional parameter in the function image.The data point of the functional parameter is more
A, the data point of multiple functional parameters is the functional parameter set.Operation is carried out to the functional parameter set, is asked
Obtain the corresponding relationship of the functional parameter data point and the remaining organ outer profile, the as described mapping data.
In method as above, with the direction of the central point of remaining organ all the points on the outer profile of the remaining organ
The mapping data of all functional parameters can be obtained in divergent-ray.That is, from the center of the remaining organ to all sides
The all the points of the outer profile of the remaining organ are covered to the countless a plurality of countless a plurality of rays of ray of transmitting.Therefore, Ke Yiying
Penetrate all functional parameters in the function image.
Fig. 5 is referred to, in one embodiment, S40 includes:
S410A determines the intersection point of the ray Yu the outer profile;
The mapping data are mapped to the intersection point by S420A;
S430A obtains the outer profile image of the remaining organ according to the intersection point.
According to the mapping data, the data in the functional parameter data point are mapped to the ray and the foreign steamer
Wide point of intersection, completes the mapping of all functional parameter data points in this approach, and the described outer of the remaining organ can be obtained
Contour images.
Fig. 6 is referred to, in one embodiment, S30 can also be realized by following steps, and S30 includes:
S310B determines the central axes of the remaining organ;
S320B is determined nearest apart from described first point on the central axes according to first point on the outer profile
Second point, described first point is any point on the outer profile;
S330B is obtained and is connected first point of target segment between the second point;
S340B, the function image for including according to the registration result and the target segment, determine functional parameter
Set, the parameter that the functional parameter set includes are part corresponding ginseng of the target segment by the remaining organ
Number;
S340A determines the mapping data according to the functional parameter set.
First point in the remaining organ outer profile is found in described the central axes for determining the remaining organ
With described first point nearest point on axis, it is determined as the second point.Described first point forms the mesh with the second point
Graticule section.The functional parameter data point in the function image that the target segment is passed through.The target segment is passed through
The function image in the functional parameter data point be it is multiple, the set of multiple functional parameter data points is institute
State functional parameter set.Operation is carried out to the functional parameter set, acquires the functional parameter data point and the remaining device
The corresponding relationship of official's outer profile, the as described mapping data.
In method as above, the corresponding functional parameter data point of every bit in the remaining organ outer profile is found out, and is obtained
To the mapping data of every bit.Every bit on the remaining organ outer profile is mapped, can be completed to all institutes
State the mapping of functional parameter.
Fig. 7 is referred to, in one embodiment, S40 includes:
The mapping data are mapped at described first point by S410B;
S420B obtains the outer profile image of the remaining organ according to described first point.
According to the mapping data, the data in the functional parameter data point are mapped to the corresponding residue
The outer profile point of organ, that is, be mapped at described first point.Described first point is any point on the remaining organ outer profile.
Therefore, in this approach, the corresponding functional parameter data point of all the points can be mapped out, the described of the remaining organ can be obtained
Outer profile image.
The remaining organ for determining that functional parameter includes in the first object image is realized by above embodiments
Mapping data on outer profile, and according to the mapping data, the outer profile image of the remaining organ is obtained, by the target
Functional parameter inside object is also mapped onto the outer profile of the target object, to be by the outer profile of the target object
It can intuitively show the internal functional parameter.Above embodiments provide the method improve data show it is intuitive
Property, improve display effect.
In one embodiment, S340A includes:
S341 determines maximum value from the functional parameter that the functional parameter set includes, using the maximum value as
The mapping data;Alternatively,
S342 determines the average value for the functional parameter that the functional parameter set includes, using the average value as described in
Map data;Alternatively,
S343 determines the integrated value for the functional parameter that the functional parameter set includes, using the integrated value as described in
Map data.
That is, the functional parameter is concentrated, and the line between every ray and the remaining organ outer profile intersection point, warp
It is available to multiple functional parameter data points to cross the function image, then, to this multiple functional parameter data point
It carries out maximizing or averages or quadrature score value, so that a data are obtained, this data and the remaining organ
Outer profile on intersection point correspond to get arrive the mapping data.
Similarly, the target segment is also available to singing the praises of the functional parameter data point by the function image,
Maximum values are carried out to this multiple described functional parameter data point or are averaged or quadrature score value, to obtain a number
According to described first point on the outer profile of this data and the remaining organ corresponds to get the mapping data are arrived.
In the present embodiment, by determining maximum value or average value from the functional parameter that the functional parameter set includes
Or integrated value, it is determined as the mapping data, improves the accuracy of data mapping.
Fig. 8 is referred to, the embodiment of the present application provides a kind of data fusion device 10, and the data fusion device 10 includes:
Registration module 100, processing module 200, determining module 300, outer profile image obtain module 400, analogue data obtains module 500
With Fusion Module 600.Wherein,
The registration module 100 is obtained for being registrated the function image of target object and the anatomic image of the target object
To registration result;
The processing module 200, for obtaining first object image and the second target figure according to the anatomic image
Picture, wherein include blood vessel in second target image, include remaining organ in the first object image;
The determining module 300, for determining functional parameter outside the remaining organ that the first object image includes
Mapping data on profile;Wherein, the functional parameter is used to characterize the moving type of residue organ described in the registration result
Condition;
The outer profile image obtains module 400, for obtaining the foreign steamer of the remaining organ according to the mapping data
Wide image;
The analogue data obtains module 500, for obtaining analogue data, wherein institute according to second target image
State distribution situation of the analogue data characterization parameter preset in the blood vessel;
The Fusion Module 600, for merging the outer profile image and the analogue data.
In one embodiment, it includes model construction unit and simulation unit that the analogue data, which obtains module 500,.Its
In, the model construction unit is used to construct the second target simulation model according to second target image.The simulation unit
For carrying out computational fluid dynamics analogue simulation, obtaining the analogue data according to the second target simulation model.
In one embodiment, the determining module 300 includes: central point determination unit, ray acquiring unit, the first function
It can parameter determination unit and mapping data determination unit.Wherein, the central point determination unit is for determining the remaining organ
Central point.The ray acquiring unit be used for obtain the central point to it is described residue organ outer profile ray.It is described
First functional parameter determination unit is used for the function image and the ray that include according to the registration result, determines function
Energy parameter sets, the parameter that the functional parameter set includes are part corresponding ginseng of the ray by the remaining organ
Number.The mapping data determination unit is used to determine the mapping data according to the functional parameter set.
In one embodiment, it includes intersection point determination unit, map unit and figure that the outer profile image, which obtains module 400,
As acquiring unit.Wherein, the intersection point determination unit is used to determine the intersection point of the ray Yu the outer profile.The mapping is single
Member is for being mapped to the intersection point for the mapping data.Described image acquiring unit is used to be obtained according to the intersection point described surplus
The outer profile image of remaining organ.
In one embodiment, the determining module 300 further include: central axes determination unit, second point determination unit, mesh
Graticule section acquiring unit and the second functional parameter set determination unit.The central axes determination unit is for determining the remaining device
The central axes of official.The second point determination unit is used to be determined on the central axes according to first point on the outer profile
Apart from first point of nearest second point, described first point is any point on the outer profile.The target segment obtains
Take unit for obtaining connection first point of target segment between the second point.The second functional parameter set is true
Order member is used for the function image for including according to the registration result and the target segment, determines functional parameter collection
It closes, the parameter that the functional parameter set includes is part corresponding parameter of the target segment by the remaining organ.
In one embodiment, it further includes first map unit that the outer profile image, which obtains module 400,.Described first
Point map unit is used to the mapping data being mapped at described first point.Described image acquiring unit is also used to according to described
A little obtain the outer profile image of the remaining organ.
In one embodiment, the mapping data determination unit is also used to the function of including from the functional parameter set
Maximum value is determined in parameter, using the maximum value as the mapping data;Alternatively, determining that the functional parameter set includes
Functional parameter average value, using the average value as the mapping data;Alternatively, determining that the functional parameter set includes
Functional parameter integrated value, using the integrated value as the mapping data.
Specific about the data fusion device limits the limit that may refer to above for the data fusion method
Fixed, details are not described herein.Modules in the data fusion device can be fully or partially through software, hardware and combinations thereof
To realize.Above-mentioned each module can be embedded in the form of hardware or independently of in the processor in computer equipment, can also be with soft
Part form is stored in the memory in computer equipment, executes the corresponding behaviour of the above modules in order to which processor calls
Make.
The application one embodiment provides a kind of computer equipment, including memory and processor, the memory storage
There is computer program.The processor performs the steps of when executing the computer program
It is registrated the function image of target object and the anatomic image of the target object, obtains registration result;
According to the anatomic image, first object image and the second target image are obtained, wherein the second target figure
Include blood vessel as in, includes remaining organ in the first object image;
Determine mapping data of the functional parameter on the outer profile for the remaining organ that the first object image includes;
Wherein, the functional parameter is used to characterize the activity situation of residue organ described in the registration result;
According to the mapping data, the outer profile image of the remaining organ is obtained;
According to second target image, analogue data is obtained, wherein the analogue data characterization parameter preset is described
Distribution situation in blood vessel;
Merge the outer profile image and the analogue data.
Computer equipment provided by the above embodiment, implementing principle and technical effect are similar with above method embodiment,
Details are not described herein.
The application one embodiment provides a kind of computer readable storage medium, is stored thereon with computer program.It is described
It is performed the steps of when computer program is executed by processor
It is registrated the function image of target object and the anatomic image of the target object, obtains registration result;
According to the anatomic image, first object image and the second target image are obtained, wherein the second target figure
Include blood vessel as in, includes remaining organ in the first object image;
Determine mapping data of the functional parameter on the outer profile for the remaining organ that the first object image includes;
Wherein, the functional parameter is used to characterize the activity situation of residue organ described in the registration result;
According to the mapping data, the outer profile image of the remaining organ is obtained;
According to second target image, analogue data is obtained, wherein the analogue data characterization parameter preset is described
Distribution situation in blood vessel;
Merge the outer profile image and the analogue data.
Computer readable storage medium provided by the above embodiment, implementing principle and technical effect and the above method are implemented
Example is similar, and details are not described herein.
Those of ordinary skill in the art will appreciate that realizing all or part of the process in above-described embodiment method, being can be with
Relevant hardware is instructed to complete by computer program, the computer program can be stored in a non-volatile computer
In read/write memory medium, the computer program is when being executed, it may include such as the process of the embodiment of above-mentioned each method.Wherein,
To any reference of memory, storage, database or other media used in each embodiment provided herein,
Including non-volatile and/or volatile memory.Nonvolatile memory may include read-only memory (ROM), programming ROM
(PROM), electrically programmable ROM (EPROM), electrically erasable ROM (EEPROM) or flash memory.Volatile memory may include
Random access memory (RAM) or external cache.By way of illustration and not limitation, RAM is available in many forms,
Such as static state RAM (SRAM), dynamic ram (DRAM), synchronous dram (SDRAM), double data rate sdram (DDRSDRAM), enhancing
Type SDRAM (ESDRAM), synchronization link (Synchlink) DRAM (SLDRAM), memory bus (Rambus) direct RAM
(RDRAM), direct memory bus dynamic ram (DRDRAM) and memory bus dynamic ram (RDRAM) etc..
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
Limitations on the scope of the patent of the present invention therefore cannot be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Protect range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.