CN109764970A - A kind of combined thermometer and bioreactor for bioreactor - Google Patents
A kind of combined thermometer and bioreactor for bioreactor Download PDFInfo
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- CN109764970A CN109764970A CN201910068371.6A CN201910068371A CN109764970A CN 109764970 A CN109764970 A CN 109764970A CN 201910068371 A CN201910068371 A CN 201910068371A CN 109764970 A CN109764970 A CN 109764970A
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- thermometer
- sheath body
- sealing ring
- bioreactor
- locking member
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- 238000007789 sealing Methods 0.000 claims abstract description 100
- 239000011521 glass Substances 0.000 claims abstract description 20
- 238000003825 pressing Methods 0.000 claims description 21
- 239000007788 liquid Substances 0.000 abstract description 15
- 238000001514 detection method Methods 0.000 abstract description 13
- 230000035945 sensitivity Effects 0.000 abstract description 9
- 238000005259 measurement Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 description 8
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 239000012530 fluid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
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Abstract
The invention discloses a kind of combined thermometers and bioreactor for bioreactor, are related to field of biotechnology.Include: sheath body, mounting hole is offered in the sheath body, is equipped with thermometer in the mounting hole；One end of the sheath body is additionally provided with the first sealing ring, and the thermometer is connected on the inside of first sealing ring, is connected to the sheath body on the outside of first sealing ring；The sheath body is equipped with locking member close to one end of first sealing ring, and the locking member is equipped with the locking hole passed through for thermometer；First sealing ring is pressed in the sheath body and the thermometer for being set in the sheath body by the locking member.The glass envelope end of thermometer can be directly disposed in bioreactor, and directly be contacted with the liquid in bioreactor, and the detection sensitivity and accuracy of thermometer are increased, and improve the calibration and measurement accuracy of system for detecting temperature.
Description
Technical field
The present invention relates to field of biotechnology, espespecially a kind of combined thermometer and biological respinse for bioreactor
Device.
Background technique
In recent years, the effect that designative species play in national economy is increasing, while country is to pharmaceutical production
Quality control requirement it is also increasingly stringent.
In microbial cultivation process, the temperature of culture solution directly affects various biologies and biochemical reaction in metabolic process
Process and feed liquid characteristic, have a direct impact cultivation results and metabolite component；It additionally can to the sterilizing of bioreactor
Have a direct impact by property.Therefore, in bioreactor the temperature detection of culture solution accuracy, to the production process of bio-pharmaceuticals
It is most important for control of product quality.So bioreactor needs often in installation and debugging and use process to culture solution
System for detecting temperature demarcated, to guarantee the accuracy of temperature control result, guarantee product quality.
There are many methods for the calibration of detection temperature, wherein most reliably, for supervision department and reactor being connect jointly using unit
The method received is the temperature using liquid in normal glass thermometer detection reactor as standard value, is surveyed to temperature of reactor
Control system is demarcated.
In practical applications, due to needing for standard thermometer to be placed in detected liquid, bioreactor is detected liquid
Liquid level will form certain liquid level static pressure, in addition bioreactor situ steam needs to maintain 0.1MPa even more when sterilizing
High tank pressure, it is desirable to when guaranteeing in glass standard thermometer insertion tank during the calibration process the pressure-bearing heatproof between tank body
Sealing.
Since glass standard thermometer material is easy to break up, between metal formed pressure-bearing heatproof sealing reliable structure compared with
For difficulty, usual way is that an interface is opened on needing the bioreactor for carrying out temperature calibration, is sealed using a leading portion
In the metal sleeve insertion tank closed, the part stayed on the outside of tank body is fixed and is sealed using sealing structure with tank body；Later
Standard thermometer is inserted into casing, the reading by reading standard thermometer demarcates temperature electrode.
Although this method solves pressure-bearing heatproof and seal request, but due to using metal sleeve, make normal temperature
Counting can only be measured with detected liquid indirectly, and the glass envelope end of standard thermometer and metal sleeve only have point contact,
There are air layers for remaining part point, reduce the detection sensitivity and accuracy of standard thermometer, the calibration and survey of system for detecting temperature
It is lower to measure accuracy.
Summary of the invention
The object of the present invention is to provide a kind of combined thermometer and bioreactor for bioreactor, thermometers
Glass envelope end can be directly disposed in bioreactor, and directly contacted, improved with the liquid in bioreactor
The detection sensitivity and accuracy of thermometer, to improve the calibration and measurement accuracy of system for detecting temperature.
Technical solution provided by the invention is as follows:
A kind of combined thermometer for bioreactor, comprising: sheath body offers peace in the sheath body
Hole is filled, is equipped with thermometer in the mounting hole；One end of the sheath body is additionally provided with the first sealing ring, first sealing ring
Inside be connected to the thermometer, be connected to the sheath body on the outside of first sealing ring；The sheath body is leaned on
One end of nearly first sealing ring is equipped with locking member, and the locking member is equipped with the locking hole passed through for thermometer；It is described
First sealing ring is pressed in the sheath body and the temperature for being set in the sheath body by locking member
Meter.
In the technical program, by the setting of locking member and the first sealing ring, the first sealing ring can be connected to thermometer
Between sheath body, the seal request between thermometer and sheath body is realized；It is opened by setting the thermometer into both ends
Mouthful sheath body in, can be directly disposed at the glass envelope end of thermometer in bioreactor, and in bioreactor
Liquid directly contacted, the detection sensitivity and accuracy of thermometer are improved, to improve system for detecting temperature
Calibration and measurement accuracy.
It further, further include the second sealing ring being set on the thermometer, the outside of second sealing ring abuts
In the sheath body.
In the technical program, by the addition of the second sealing ring, second between thermometer and sheath body is realized
Sealing, increases sealing reliability.
Further, the outer sheath of the thermometer is equipped with pressing sleeve, offers in the sheath body and connects with the mounting hole
Logical indent；One end of the pressing sleeve is connected to first sealing ring, and it is close that the other end of the pressing sleeve is connected to described second
Seal.
In the technical program, by the setting of pressing sleeve, increase between the first sealing ring, the second sealing ring and thermometer
Constraint, pressing sleeve can limit sealing ring, reduce the possibility of thermometer shaking, increase the stability of thermometer.
Further, the locking member is additionally provided with casing far from one end of the sheath body, is equipped with and is used in described sleeve pipe
The link slot that thermometer passes through；The one end of the sheath body far from described sleeve pipe is arranged in the glass envelope end of the thermometer,
The other end of the thermometer is embedded in described sleeve pipe.
In the technical program, by the setting of casing, the exposed thermometer on the outside of bioreactor is protected, is subtracted
The possibility of small thermometer damage.
Further, the sheath body is equipped with far from one end of described sleeve pipe and adjusts window, described in the adjusting window opening's edge
The length direction of sheath body is opened in the sheath body.
In the technical program, the glass envelope end of thermometer can be generally placed at the position for adjusting window, pass through adjusting window
The setting of mouth, user is convenient for observing directly position of the thermometer in sheath body, convenient for adjusting thermometer in biological respinse
Insertion depth in device detects fluid temperature in tank body in place, while protecting thermometer, convenient in reactor
Liquid improves the sensitivity and high accuracy of temperature detection in the flowing at thermometer glass ball end.
Further, watch window is also provided in described sleeve pipe, the watch window is opened along the length direction of described sleeve pipe
Set on described sleeve pipe.
In the technical program, user can notify watch window to observe directly the scale of thermometer, without removing set
Pipe, while protecting thermometer, additionally it is possible to realize that the temperature value of thermometer is read, convenient for the operation of user.
Further, the fixing piece for being connected on reactor body, the fixing piece are arranged in the sheath body
The outside of the reactor body, side of the fixing piece far from the locking member are set to close to the side of the locking member
It is set in the reactor body.
In the technical program, by the setting of fixing piece, the connection realized between reactor body and sheath body is solid
It is fixed, the possibility of sheath body shaking is reduced, the possibility of thermometer shaking is then reduced, increases the stability of thermometer.
Further, the fixing piece is equipped with exterior seal ring far from the sheath body of the locking member side, described outer close
The outside of seal is used to be connected to the inner wall of the reactor body.
In the technical program, by the setting of exterior seal ring, the sealing of sheath body and bioreactor is realized.
Further, pressure ring is equipped between the sheath body and the locking member；The locking member is also used to the pressure
Ring is pressed in sheath body, and first sealing ring is pressed between the pressure ring and the sheath body.
In the technical program, by the setting of pressure ring, between pressure ring, thermometer and sheath body can secondary seal, into
One step realizes the seal request of bioreactor.
An object of the present invention, which also resides in, provides a kind of bioreactor, comprising: reactor body, the reactor sheet
Interface is offered on body, and a kind of combined thermometer for bioreactor is installed on the interface.
In the technical program, by the setting of locking member and the first sealing ring, the first sealing ring can be connected to thermometer
Between sheath body, the seal request between thermometer and sheath body is realized；It is opened by setting the thermometer into both ends
Mouthful sheath body in, can be directly disposed at the glass envelope end of thermometer in bioreactor, and in bioreactor
Liquid directly contacted, the detection sensitivity and accuracy of thermometer are improved, to improve system for detecting temperature
Calibration and measurement accuracy.
Compared with prior art, a kind of combined thermometer and biological respinse for bioreactor provided by the invention
Device has the advantages that
1, the glass envelope end of thermometer can be directly disposed in bioreactor, and with the liquid in bioreactor into
Row directly contacts, and the detection sensitivity and accuracy of thermometer is improved, to improve the calibration and survey of system for detecting temperature
Measure accuracy.
2, by the setting of pressing sleeve, the constraint between the first sealing ring, the second sealing ring and thermometer, pressing sleeve energy are increased
It is enough that sealing ring is limited, the possibility of thermometer shaking is reduced, the stability of thermometer is increased.
3, sealing ring is limited by the setting of the first sealing ring and the second sealing ring and locking member and pressing sleeve,
Reduce the possibility that thermometer shakes, increases the stability of thermometer；The addition of second sealing ring simultaneously, and the second sealing ring supports
It is connected in the inner wall i.e. sheath body of thermometer, indent, realizes second of sealing between thermometer and sheath body, increase
The reliability of bioreactor sealing.
4, by the setting of fixing piece, being connected and fixed between reactor body and sheath body is realized, reduces shield
The possibility that main body is shaken is covered, the possibility of thermometer shaking is then reduced, increases the stability of thermometer.
5, by the setting of exterior seal ring, the sealing of sheath body and bioreactor is realized.
Detailed description of the invention
Below by clearly understandable mode, preferred embodiment is described with reference to the drawings, bioreactor is used for one kind
Combined thermometer and above-mentioned characteristic, technical characteristic, advantage and its implementation of bioreactor be further described.
Fig. 1 is a kind of structural schematic diagram of the combined thermometer for bioreactor of the present invention.
Drawing reference numeral explanation: 10. sheath bodies, 11. mounting holes, 12. indents, 13. adjusting windows, 20. thermometers, 31.
First sealing ring, 32. second sealing rings, 33. exterior seal rings, 40. locking members, 41. locking holes, 50. pressure rings, 60. pressing sleeves, 70.
Casing, 71. watch windows, 80. fixing pieces.
Specific embodiment
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, Detailed description of the invention will be compareed below
A specific embodiment of the invention.It should be evident that drawings in the following description are only some embodiments of the invention, for
For those of ordinary skill in the art, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing, and obtain other embodiments.
To make simplified form, part relevant to invention is only schematically shown in each figure, they do not represent it
Practical structures as product.In addition, so that simplified form is easy to understand, with the portion of identical structure or function in some figures
Part only symbolically depicts one of those, or has only marked one of those.Herein, "one" is not only indicated " only
This ", it can also indicate the situation of " more than one ".
A kind of embodiment provided according to the present invention, as shown in Figure 1, a kind of combined temperature for bioreactor
Meter, including, sheath body 10, sheath body 10 is long tubular, mounting hole 11 is equipped in sheath body 10, mounting hole 11 is along its length
Degree direction is provided in sheath body 10, and sheath body 10 is run through at the both ends of mounting hole 11；Thermometer is equipped in mounting hole 11
20, thermometer 20 can penetrate in sheath body 10 from one end of sheath body 10.
One end of sheath body 10 is equipped with the first sealing ring 31, and in the present embodiment, the first sealing ring 31 is arranged in sheath master
The left end of body 10；First sealing ring 31 is ring-type, and the inside of the first sealing ring 31 is connected to thermometer 20, the first sealing ring 31
Outside is connected to sheath body 10, i.e., is clamped on sheath body 10 and temperature by the first sealing ring 31 in one end of sheath body 10
Between degree meter 20, the sealing between sheath body and thermometer is realized.
Sheath body 10 is equipped with locking member 40 close to one end of the first sealing ring 31, i.e., the setting of locking member 40 is in the first sealing
The left side of circle 31；Locking member 40 is equipped with the locking hole 41 passed through for thermometer 20, and locking member 40 can be set in sheath master
On body 10, and the first sealing ring 31 is pressed between sheath body 10 and thermometer 20, i.e., locking member 40 can be in sheath master
One end of body 10 is loaded and unloaded, and when locking member 40 is mounted in sheath body 10, and locking member 40 can be by the first sealing ring
31 are pressed on sheath body 10 and thermometer 20.In the present embodiment, sheath can be arranged in the glass envelope end of thermometer 20
The left or right of sheath body 10 is arranged in any end of main body 10, the i.e. glass envelope of thermometer 20.
In the present embodiment, by the setting of locking member 40 and the first sealing ring 31, the first sealing ring 31 can be connected to temperature
Between degree meter 20 and sheath body 10, the seal request between sheath body 10 and thermometer 20 is realized；By by thermometer
20 are arranged in the sheath body 10 of both ends open, i.e. the glass envelope end of thermometer 20 can be directly disposed at reactor body
It is interior, and directly contacted with the liquid in reactor body, the detection sensitivity and accuracy of thermometer 20 are increased, thus
Improve the calibration and measurement accuracy of system for detecting temperature.
Preferably, pressure ring 50 is equipped between sheath body 10 and locking member 40, locking member 40 is also used to compress pressure ring 50
It is pressed between pressure ring 50 and sheath body 10 in sheath body 10, and by the first sealing ring 31；That is the setting of locking member 40 is being protected
When covering in main body 10, pressure ring 50 can be pressed to sheath body 10, the first sealing ring 31 can be pressed in pressure ring 50, sheath body
Between 10 and thermometer 20.
By the setting of pressure ring 50, between pressure ring 50 and thermometer 20 can excellent sealing, be furthermore achieved biological anti-
Answer the seal request of device.
In the present embodiment, since thermometer 20 is standard component, sheath body 10 offers first close to the side of pressure ring 50
Seal face, pressure ring 50 are equipped with the second seal face close to the side of sheath body 10, and the second seal face is connected to the first seal face, the
One seal face can be formed with the second seal face by chamfering, can form one between sheath body 10, pressure ring 50 and thermometer 20
A space for being used to accommodate the first sealing ring 31；Preferably, the section of the first sealing ring 31 is circle, and will be pressed in locking member 40
When ring 50 is pressed in sheath body 10, the first sealing ring 31 can be connected to pressure ring 50, sheath body 10 and thermometer simultaneously
Between 20, the first sealing ring 31 is connected between sheath body 10 and thermometer 20, realize thermometer 20 and sheath body 10 it
Between first time sealing, the first sealing ring 31 abuts between thermometer 20 and pressure ring 50, realizes thermometer 20 and sheath body
Second of sealing between 10.
In the present embodiment, locking member 40 can be clamped or any connection type such as hasp connection or threaded connection is connected to shield
It covers in main body 10, it is preferable that locking member 40 is locking nut, and 40 use of locking member is threaded in sheath body 10, passes through
Threaded connection between locking member 40 and sheath body 10 is easy to implement the locking and release of locking member 40.
Preferably, in the present embodiment, when thermometer 20 is arranged in sheath body 10 along the sliding of its axis direction, the
One sealing ring 31 can be closely connected on thermometer 20 always；Further, when locking member 40 is locked in sheath body 40,
Locking assembly 40 can also increase the constraint between thermometer 20 and sheath body 10, reduce thermometer 20 along its axis direction
The possibility of sliding increases stability of the thermometer 20 in sheath body 10.When needing to adjust the position of thermometer 20, unclamp
Locking member 40, the constraint between release temperature meter 20 and sheath body 10, can be realized the sliding of thermometer 20, without that will lock
Part 40 discharges completely, operates more convenient.
Another embodiment provided according to the present invention, as shown in Figure 1, a kind of combined temperature for bioreactor
The difference of meter, the present embodiment and the first embodiment is the addition of the second sealing ring 32.
It further include the second sealing ring being set on thermometer 20 in the present embodiment on the basis of the first embodiment
32, the outside of the second sealing ring 32 is connected to sheath body 10；By the addition of the second sealing ring 32, realize thermometer 20 with
Second of sealing between sheath body 10, increases sealing reliability.Specifically, it is opened up in sheath body 10 close for second
The indent 12 that seal 32 is arranged, the inside of the second sealing ring 32 can be connected on thermometer 20, the outside of the second sealing ring 32
It is connected on the inner wall of indent 12.
Preferably, the outer sheath of thermometer 20 is equipped with pressing sleeve 60, offers in sheath body 10 and to be connected to mounting hole 11
Indent 12；One end of pressing sleeve 60 can be connected to the first sealing ring 31, and the other end of pressing sleeve 60 can be connected to the second sealing ring
32.By the setting of pressing sleeve 60, the constraint between the first sealing ring 31, the second sealing ring 32 and thermometer 20, pressing sleeve are increased
60 can limit sealing ring (31,32), reduce the possibility of the shaking of thermometer 20, increase the stabilization of thermometer 20
Property.
Since one end of pressing sleeve 60 can be connected on the first sealing ring 31, one kind in conjunction with described in the first embodiment
For the combined thermometer 20 of bioreactor, the first seal face can be provided in sheath body 10, the first sealing ring 31
It can directly be connected on pressure ring 50, sheath body 10, thermometer 20 and pressing sleeve 60, the first sealing ring 31 can be realized thermometer
It is sealed between 20 and sheath body 10；Or third seal face directly is opened up close to one end of the first sealing ring 31 in pressing sleeve 60, the
Two seal faces and third seal face form the space for accommodating the first sealing ring 31, and the first sealing ring 31 can be directly connected to
On pressure ring 50, thermometer 20 and pressing sleeve 60, the first sealing ring 31 can be realized dual between thermometer 20 and sheath body 10
Sealing, and suitable sealing means are chosen according to the needs of user.
On the basis of the first embodiment, when thermometer 20 generates sliding trend, the second sealing ring 32 also can be steady
Surely the constraint for being connected on thermometer 20, while ensure that sealing and thermometer 20 being slided.
Another embodiment provided according to the present invention, as shown in Figure 1, a kind of combined temperature for bioreactor
The difference of meter, the present embodiment and the first embodiment is the addition of casing 70.
On the basis of the first embodiment, in the present embodiment, locking member 40 is equipped with set far from one end of sheath body 10
Pipe 70, casing 70 is interior to be equipped with the link slot passed through for thermometer 20, and it is remote that sheath can be arranged in the glass envelope end of thermometer 20
One end from casing 70, the other end of thermometer 20 are embedded in casing 70, i.e., a left side for locking member 40 can be arranged in casing 70
End；By the setting of casing 70, the exposed casing 70 on the outside of reactor body is protected, reduces the damage of thermometer 20
Possibility.
Specifically, casing 70 can be directly integrally formed, and open up link slot on the right side of casing 70；Or casing 70 is chosen
The pipe fitting of both ends open, and cover board is added in the left end opening of pipe fitting, form link slot；Casing 70 can be clamped or hasp connects
It any connection type such as connecing or is threadedly coupled to be connected on locking member 40, it is preferable that casing 70 is threaded on locking member 40,
Convenient for the handling of casing 70.
Preferably, sheath body 10 is equipped with far from one end of casing 70 and adjusts window 13, i.e. adjusting window 13 setting is being protected
The right end of main body 10 is covered, window 13 is adjusted and is provided in sheath body 10 along the length direction of sheath body 10, thermometer 20
Glass envelope end can be in the position for adjusting window 13, and by adjusting the setting of window 13, user is convenient for observing directly thermometer
20 position in sheath body 10, convenient for adjusting insertion depth of the thermometer 20 in reactor body, in place
Fluid temperature in tank body is detected, stream while protecting thermometer, convenient for liquid in reactor at thermometer glass ball bubble end
It is dynamic, improve the sensitivity and accuracy of temperature detection.
Preferably, watch window 71 is additionally provided on casing 70, watch window 71 can be opened up along the length direction of casing 70
On casing 70, watch window 71 has waist-shaped hole, and user can notify watch window 71 to observe directly the scale of thermometer 20,
Without removing casing 70, while protecting thermometer 20, additionally it is possible to realize that the temperature value of thermometer 20 is read, convenient for using
The operation at family.
According to the improvement of above-described embodiment, in the present embodiment, also set on stretching out the thermometer 20 on the outside of bioreactor
There is attemperator (not shown), attemperator can be arranged on sheath body 10 or casing 70, pass through setting for attemperator
It sets, thermometer can be made to be detected under conditions of more complying with standard thermometer requirement, thermometer is further improved
Accuracy in detection.
The another embodiment provided according to the present invention, as shown in Figure 1, a kind of combined temperature for bioreactor
The difference of meter, the present embodiment and the first embodiment is the addition of fixing piece 80.
On the basis of the first embodiment, in the present embodiment, sheath body 10 is equipped with for being connected to reactor sheet
The outside of reactor body, fixing piece 80 can be arranged in close to the side of locking member 40 for fixing piece 80 on body, fixing piece 80
It is arranged in reactor body far from 40 side side of locking member, therefore the outside of reactor body can be arranged in locking member 40,
The setting for passing through fixing piece 80 simultaneously, realizes the connection between reactor body and sheath body 10, reduces sheath body
10 possibility shaken, then reduce the possibility of the shaking of thermometer 20, increase the stability of thermometer 20.
Preferably, fixing piece 80 is threaded in sheath body 10, convenient for sheath body 10 is pressed on reactor sheet
On body.Interface is offered on reactor body, sheath body 10 can pass through interface close to one end of 20 glass ball bulb of thermometer
Into in reactor body, fixing piece 80 can be connected on the reactor body on the outside of interface.
Fixing piece 80 is equipped with exterior seal ring 33 far from the side of locking member 40, and exterior seal ring 33 can be connected to reactor
On interface, by the setting of exterior seal ring 33, the seal degree between bioreactor is further increased, biology is increased
The reliability of reactor sealing.Specifically, exterior seal ring 33 can be connected on the inner wall of reactor body interface.
A kind of embodiment provided according to the present invention, as shown in Figure 1, a kind of bioreactor, comprising:
Reactor body (not shown) offers interface on reactor body, is equipped on interface above-mentioned any one
The combined thermometer of bioreactor is used for described in kind embodiment.
It should be noted that above-described embodiment can be freely combined as needed.The above is only of the invention preferred
Embodiment, it is noted that for those skilled in the art, in the premise for not departing from the principle of the invention
Under, several improvements and modifications can also be made, these modifications and embellishments should also be considered as the scope of protection of the present invention.
Claims (10)
1. a kind of combined thermometer for bioreactor characterized by comprising
Sheath body offers mounting hole in the sheath body, is equipped with thermometer in the mounting hole；
One end of the sheath body is additionally provided with the first sealing ring, is connected to the thermometer on the inside of first sealing ring,
The sheath body is connected on the outside of first sealing ring；
The sheath body is equipped with locking member close to one end of first sealing ring, and the locking member, which is equipped with, is used for thermometer
The locking hole passed through；
The locking member for being set in the sheath body, and by first sealing ring be pressed in the sheath body with
The thermometer.
2. a kind of combined thermometer for bioreactor according to claim 1, it is characterised in that:
Further include the second sealing ring being set on the thermometer, the sheath master is connected on the outside of second sealing ring
Body.
3. a kind of combined thermometer for bioreactor according to claim 2, it is characterised in that:
The outer sheath of the thermometer is equipped with pressing sleeve, offers the indent being connected to the mounting hole in the sheath body；
One end of the pressing sleeve is connected to first sealing ring, and the other end of the pressing sleeve is connected to second sealing ring.
4. a kind of combined thermometer for bioreactor according to claim 1, it is characterised in that:
The locking member is additionally provided with casing far from one end of the sheath body, is equipped in described sleeve pipe and is used for what thermometer passed through
Link slot；
The glass envelope end of the thermometer is arranged in the one end of the sheath body far from described sleeve pipe, the thermometer it is another
End is embedded in described sleeve pipe.
5. a kind of combined thermometer for bioreactor according to claim 4, it is characterised in that:
The sheath body is equipped with far from one end of described sleeve pipe and adjusts window, the length of sheath body described in the adjusting window opening's edge
Degree direction is opened in the sheath body.
6. a kind of combined thermometer for bioreactor according to claim 4, it is characterised in that:
Watch window is also provided in described sleeve pipe, the watch window is opened in the set along the length direction of described sleeve pipe
Pipe.
7. a kind of combined thermometer for bioreactor according to claim 1, it is characterised in that:
The fixing piece for being connected on reactor body is arranged in the sheath body, the fixing piece is close to the locking
The side of part is set to the outside of the reactor body, and the fixing piece is set to described anti-far from the side of the locking member
It answers in device ontology.
8. a kind of combined thermometer for bioreactor according to claim 7, it is characterised in that:
The fixing piece is equipped with exterior seal ring far from the sheath body of the locking member side, and the outside of the exterior seal ring is used
In on the inner wall for being connected to the reactor body.
9. a kind of combined thermometer for bioreactor, feature described according to claim 1~any one of 8
It is:
Pressure ring is equipped between the sheath body and the locking member；
The locking member is also used to for the pressure ring being pressed in sheath body, and first sealing ring is pressed in the pressure ring
Between the sheath body.
10. a kind of bioreactor characterized by comprising
Reactor body offers interface on the reactor body, is equipped in claim 1~9 on the interface any
A kind of combined thermometer for bioreactor described in one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910068371.6A CN109764970A (en) | 2019-01-24 | 2019-01-24 | A kind of combined thermometer and bioreactor for bioreactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910068371.6A CN109764970A (en) | 2019-01-24 | 2019-01-24 | A kind of combined thermometer and bioreactor for bioreactor |
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| Publication Number | Publication Date |
|---|---|
| CN109764970A true CN109764970A (en) | 2019-05-17 |
Family
ID=66455320
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|---|---|---|---|
| CN201910068371.6A Pending CN109764970A (en) | 2019-01-24 | 2019-01-24 | A kind of combined thermometer and bioreactor for bioreactor |
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| CN202903351U (en) * | 2012-11-22 | 2013-04-24 | 秦皇岛科维克科技有限公司 | Device for sealing and fixing thermometer used in reaction still |
| JP2018080948A (en) * | 2016-11-14 | 2018-05-24 | 株式会社フルヤ金属 | Thermistor |
| CN209513074U (en) * | 2019-01-24 | 2019-10-18 | 华东理工大学青岛创新研究院 | A kind of combined thermometer and bioreactor for bioreactor |
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2019
- 2019-01-24 CN CN201910068371.6A patent/CN109764970A/en active Pending
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| JP2009133819A (en) * | 2007-11-02 | 2009-06-18 | Kobelco Eco-Solutions Co Ltd | Temperature measuring instrument |
| CN202177463U (en) * | 2011-07-14 | 2012-03-28 | 江苏大成医药化工有限公司 | Temperature measuring device of bromoacetyl bromide reaction vessel |
| CN202903351U (en) * | 2012-11-22 | 2013-04-24 | 秦皇岛科维克科技有限公司 | Device for sealing and fixing thermometer used in reaction still |
| JP2018080948A (en) * | 2016-11-14 | 2018-05-24 | 株式会社フルヤ金属 | Thermistor |
| CN209513074U (en) * | 2019-01-24 | 2019-10-18 | 华东理工大学青岛创新研究院 | A kind of combined thermometer and bioreactor for bioreactor |
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