CN109754448A - A kind of CT heart scanning artifact correction method and its system - Google Patents
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Abstract
The invention discloses a kind of CT heart scanning artifact correction method and its system, the method includes the steps: pass through two overlapping images that heart scanning obtains the adjacent cardiac period；Image registration is carried out to overlapping image and obtains optimal spatial transformation；It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.By the way that the relative movement parameters (spatial alternation Tr) in different heart heart beat cycles are covered in image reconstruction algorithm, relative movement parameters are adjusted by optimization method, to reduce the step-like artifact of different heartbeat juncture areas, the problems such as improving picture quality, can solve hardware technology insurmountable motion artifacts.
Description
Technical field
The present invention relates to medical imaging technology field more particularly to a kind of CT heart scanning artifact correction method and its
System.
Background technique
In the prior art, the heart scanning of heart real time diagram technology scans number by obtaining diastole in adjacent cardiac period
According to certain overlapping, Lai Shixian cardiac imaging alleviates heartbeat bring artifact well；However, the overlapping being not processed
Region can still be moved due to patient respiration and carelessly, generate splicing artifact, and stronger artifact may bring more by force blood vessel tracing
Failure, cardiac imaging do not plan a successor situations such as discontinuous.
Therefore, the existing technology needs to be improved and developed.
Summary of the invention
The technical problem to be solved in the present invention is that in view of the above drawbacks of the prior art, providing a kind of CT heart scanning
Artifact correction method and its system, it is intended to solve the problems, such as that CT heart scanning in the prior art generates splicing artifact.
The technical proposal for solving the technical problem of the invention is as follows:
A kind of CT heart scanning artifact correction method, wherein comprising steps of
Two overlapping images in adjacent cardiac period are obtained by heart scanning；
Image registration is carried out to overlapping image and obtains optimal spatial transformation；
It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.
The CT heart scanning artifact correction method, wherein described pair of overlapping image carries out image registration and obtain optimal sky
Between shift step specifically include:
Extract the image information of two overlapping images in adjacent cardiac period and respectively as reference picture and figure subject to registration
Image subject to registration and image subject to registration are formed information space, determine spatial alternation by picture；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the first optimal spatial transformation.
The CT heart scanning artifact correction method, wherein described pair of overlapping image carries out image registration and obtain optimization figure
As step further include:
Reference picture and image subject to registration are replaced mutually；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the second optimal spatial transformation.
The CT heart scanning artifact correction method, wherein the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates that the second optimal spatial becomes
It changes, I1 and I2 respectively indicate two images in adjacent cardiac period.
The CT heart scanning artifact correction method, wherein the heart scanning is using multiple synchronous according to heartbeat phase
Step-scan or helical scanning.
A kind of CT heart scanning artifact correction system, wherein include: processor, and what is be connected to the processor deposit
Reservoir,
The memory is stored with CT heart scanning artifact correction program, and the CT heart scanning artifact correction program is by institute
It states when processor executes and performs the steps of
Two overlapping images in adjacent cardiac period are obtained by heart scanning；
Image registration is carried out to overlapping image and obtains optimal spatial transformation；
It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.
The CT heart scanning artifact correction system, wherein the CT heart scanning artifact correction program is by the processing
When device executes, also perform the steps of
Extract the image information of two overlapping images in adjacent cardiac period and respectively as reference picture and figure subject to registration
Image subject to registration and image subject to registration are formed information space, determine spatial alternation by picture；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the first optimal spatial transformation.
The CT heart scanning artifact correction system, wherein the CT heart scanning artifact correction program is by the processing
When device executes, also perform the steps of
Reference picture and image subject to registration are replaced mutually；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the second optimal spatial transformation.
The CT heart scanning artifact correction system, wherein the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates that the second optimal spatial becomes
It changes, I1 and I2 respectively indicate two images in adjacent cardiac period.
The 1 CT heart scanning artifact correction system, wherein the heart scanning is using multiple synchronous according to heartbeat phase
Step-scan or helical scanning.
The utility model has the advantages that by the way that the relative movement parameters (spatial alternation Tr) in different heart heart beat cycles are covered image
In algorithm for reconstructing, relative movement parameters are adjusted by optimization method, to reduce the step-like artifact of different heartbeat juncture areas,
The problems such as improving picture quality, can solve hardware technology insurmountable motion artifacts.
Detailed description of the invention
Fig. 1 is the flow chart of CT heart scanning artifact correction method preferred embodiment in the present invention.
Fig. 2 is the heart scanning schematic diagram in the present invention based on heart real time figure.
Fig. 3 is cardiac image sagittal plane original graph.
Fig. 4 is cardiac image sagittal plane correction chart.
Fig. 5 is the functional schematic block diagram of CT heart scanning artifact correction system preferred embodiment in the present invention.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention clearer and more explicit, right as follows in conjunction with drawings and embodiments
The present invention is further described.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and do not have to
It is of the invention in limiting.
Please refer to Fig. 1-Fig. 4, the present invention provides a kind of some embodiments of CT heart scanning artifact correction method.
As shown in Figure 1, CT heart scanning artifact correction method of the invention, comprising the following steps:
Step S100, two overlapping images in adjacent cardiac period are obtained by heart scanning.
Specifically, the application of heart real time figure is moved relatively gentle feature using diastole in the heartbeat period, adopted
Collect data source (the first image I1, second image I2, third image in such as Fig. 2 of the period in multiple cardiac cycles
I3), the three-dimensional reconstruction data for obtaining metastable heart scanning, greatly improve image quality when CT scan heart.
In first image with the overlapping image of second image overlapping region be I1overlap, in second image
The overlapping image of one image overlapping region is I2overlap.The present invention is corrected by adjacent cardiac period overlapping region algorithm, is come
Solve breathing and movement bring image artifacts
The heart scanning is using the multiple step-scans or helical scanning synchronous according to heartbeat phase.
Step S200, image registration is carried out to overlapping image and obtains optimal spatial transformation.
Image registration is the process of similarity transformation (Tr) between obtaining image, as shown in formula (1), between meeting image most
It is small estimate in the case where, obtain optimal mapping.
Tr=Reg (I1overlap,I2overlap)s.t.min{Dif(Tr(I2overlap),I1overlap)} (1)
Wherein Reg () indicates image registration, I1overlapIndicate overlapping Chong Die with second image in first image
Image, I2overlapIndicate overlapping image Chong Die with first image in second image.S.t. it indicates and if only if min
() indicates minimum value, and Dif () indicates that image registration is estimated.
Common method for registering images has gradient descent algorithm, Guass-Newton algorithm, Powell algorithm etc.；The present invention
Technology uses gradient descent algorithm, and gradient decline is the method for solving Unconstrained Optimization Problem by iteration, the i.e. derivation of equation (1)
In Dif function optimal solution.It is assumed that I1overlap、I2overlapConstituting-functions f (x) solves function f (x) by way of iteration
Optimal solution, give initial point xk, next point is found by iteration, to obtain more preferably functional value.Gradient descent method is specific
Steps are as follows:
1) x is pinpointedkThe negative gradient direction at place is the direction of search,
2) direction of search is being had selected, along direction of search selected element xk+1, xk+1=xk-tk×pk, wherein tkFor along negative gradient
The detection range in direction, referred to as step factor；
3) judge whether stop criterion meets: if satisfied, output xk+1, f (xk+1)；If not satisfied, setting k=k+1, step is gone to
It is rapid 1), stop criterion be min { Dif (Tr (I2overlap),I1overlap), i.e. minimum is estimated in image registration.
The step S200 is specifically included:
Step S211, extract the image information of two of adjacent cardiac period overlapping images and respectively as reference picture and
Image subject to registration and image subject to registration are formed information space, determine spatial alternation by image subject to registration.
In the present invention, the first image and the second image all can serve as reference picture, also all can serve as image subject to registration,
Certainly, when the first image is reference picture, the second image is image subject to registration.Therefore, two aspect registrations to be carried out.For example, first
Using the first image as reference picture, and the second image is that image subject to registration is registrated, and both sides registration can be simultaneously certainly
It carries out.
Step S212, image subject to registration is registrated according to spatial alternation to obtain transformed image.
Here spatial alternation uses initial space transformation Tr1, then registration obtains transformed image Tr for the first time1
(I2overlap)。
Step S213, the similarity measure of transformed image and reference picture is calculated.
Common image registration Measurement Method has Euclidean distance, mean square error, mutual information etc.；The technology of the present invention uses mutual trust
Breath is estimated, and mutual information is the measurement of similarity between image, and similitude is higher between the bigger representative image of its value.
Assuming that A corresponds to the Tr (I2 in formula (1)overlap), then the comentropy of A is H (A)=- ∑aPA(a)log2PA(a)。
Wherein, a is positive integer, PA() indicates a-quadrant (i.e. I2overlapOverlapping region) probability of a-th of symbol is taken, ∑ indicates summation
Symbol, log indicate log.B corresponds to the Tr (I1 in formula (1)overlap), then comentropy is H (B)=- ∑bPB(b)
log2PB(b).Wherein, b indicates positive integer, PB() indicates B area (i.e. I1overlapOverlapping region) take b-th of symbol
Probability.The united comentropy of A and B is H (A, B)=- ∑a,bPA,B(a,b)log2PA,B(a, b), PA, B() indicates that a-quadrant takes
A-th of symbol and B area take the probability of b-th of symbol；Calculate A and B mutual information measure be
Step S214, when similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister.Here pre-
If condition, that is, stop criterion, min { Dif }.Specifically, new picture element position information is obtained based on Reg (gradient decline), passes through B-
Spline interpolation calculation updates spatial alternation Tr.
Specifically, initial space transformation is updated to Tr2, it is Tr that registration, which obtains transformed image, again2(I2overlap)。
Step S215, when similarity measure meets preset condition, output the first optimal spatial transformation.
When similarity measure minimum, the first optimal spatial transformation Tr 1 is exported.Certainly it is with reference to figure that this, which is with the first image,
As the first obtained optimal spatial transformation Tr 1, it is also necessary to which the second optimal spatial obtained using the second image as reference picture becomes
Change Tr2.
Step S221, reference picture and image subject to registration are replaced mutually.
By reference picture and image exchange subject to registration, that is to say, that using the second image as reference picture, the first image be to
It is registrated image.
Step S222, image subject to registration is registrated according to spatial alternation to obtain transformed image.
It referring to step S212, is converted, certainly, spatial alternation here can be initial space transformation, be also possible to
The transformation of first optimal spatial is more saved the time using the transformation of the first optimal spatial, is calculated faster.
Step S223, the similarity measure of transformed image and reference picture is calculated.
Similarity measure is calculated referring to step S213.
Step S224, when similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister.
It is reregistered referring to S214.
Step S225, when similarity measure meets preset condition, output the second optimal spatial transformation.
When similarity measure meets preset condition, the second optimal spatial transformation Tr 2 is exported.
Step S300, it is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition sequential chart
Picture.
Specifically, the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates that the second optimal spatial becomes
It changes, I1 and I2 respectively indicate two images in adjacent cardiac period.w1For the number between 1 to 0, w2For the number between 0 to 1, and it is full
Sufficient sum of the two is 1.
As shown in Figure 4 and Figure 5, interposition is equipped with noticeable steps shape artifact on the right side of original graph, is connected in which corrected
Continuous image namely correction chart, the step-like artifact in right side middle position without.
It is worth noting that by the way that the relative movement parameters (spatial alternation Tr) in different heart heart beat cycles are covered
In image reconstruction algorithm, relative movement parameters are adjusted by optimization method, to reduce the step-like of different heartbeat juncture areas
Artifact improves picture quality.By the image of segment reconstruction difference heartbeat, then by non-rigid body model method estimate not
It is mutually registrated with the relative motion of heartbeat juncture area, and the image that different heartbeats are rebuild.Pass through the algorithm process on software
Image improves cardiac image quality, has more wide applicability compared to original technology, can solve hardware technology can not solve
Motion artifacts the problems such as.
The present invention also provides a kind of preferred embodiments of CT heart scanning artifact correction system:
As shown in figure 5, the CT heart scanning artifact correction system of the embodiment of the present invention, comprising: processor 10, and with institute
The memory 20 of the connection of processor 10 is stated,
The memory 20 is stored with CT heart scanning artifact correction program, the CT heart scanning artifact correction program quilt
The processor 10 performs the steps of when executing
Two overlapping images in adjacent cardiac period are obtained by heart scanning；
Image registration is carried out to overlapping image and obtains optimal spatial transformation；
It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image, it is specific as above
It is described.
When the CT heart scanning artifact correction program is executed by the processor 10, also perform the steps of
Extract the image information of two overlapping images in adjacent cardiac period and respectively as reference picture and figure subject to registration
Image subject to registration and image subject to registration are formed information space, determine spatial alternation by picture；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the first optimal spatial transformation, as detailed above.
When the CT heart scanning artifact correction program is executed by the processor 10, also perform the steps of
Reference picture and image subject to registration are replaced mutually；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the second optimal spatial transformation, as detailed above.
In the present embodiment, the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates that the second optimal spatial becomes
It changes, I1 and I2 respectively indicate two images in adjacent cardiac period.
In the present embodiment, the heart scanning is using the multiple step-scans or helical scanning synchronous according to heartbeat phase.
In conclusion a kind of CT heart scanning artifact correction method provided by the present invention and its system, the method packet
It includes step: obtaining two overlapping images in adjacent cardiac period by heart scanning；Image registration is carried out to overlapping image to obtain
Optimal spatial transformation；It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.It is logical
It crosses and the relative movement parameters (spatial alternation Tr) in different heart heart beat cycles is covered in image reconstruction algorithm, pass through optimization
Method adjusts relative movement parameters, to reduce the step-like artifacts of different heartbeat juncture areas, improves picture quality, can solve
Certainly the problems such as hardware technology insurmountable motion artifacts.
It should be understood that the application of the present invention is not limited to the above for those of ordinary skills can
With improvement or transformation based on the above description, all these modifications and variations all should belong to the guarantor of appended claims of the present invention
Protect range.
Claims (10)
1. a kind of CT heart scanning artifact correction method, which is characterized in that comprising steps of
Two overlapping images in adjacent cardiac period are obtained by heart scanning；
Image registration is carried out to overlapping image and obtains optimal spatial transformation；
It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.
2. CT heart scanning artifact correction method according to claim 1, which is characterized in that described pair of overlapping image carries out figure
It is specifically included as registration obtains optimal spatial shift step:
Two for extracting the adjacent cardiac period are overlapped the image information of image and respectively as reference pictures and image subject to registration, will
Image subject to registration and image subject to registration form information space, determine spatial alternation；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the first optimal spatial transformation.
3. CT heart scanning artifact correction method according to claim 2, which is characterized in that described pair of overlapping image carries out figure
As registration obtains optimization image step further include:
Reference picture and image subject to registration are replaced mutually；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the second optimal spatial transformation.
4. CT heart scanning artifact correction method according to claim 3, which is characterized in that the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates the transformation of the second optimal spatial, I1
Two images in adjacent cardiac period are respectively indicated with I2.
5. CT heart scanning artifact correction method according to claim 1, which is characterized in that the heart scanning is using multiple
According to heartbeat phase synchronous step-scan or helical scanning.
6. a kind of CT heart scanning artifact correction system characterized by comprising processor, and be connected to the processor
Memory,
The memory is stored with CT heart scanning artifact correction program, and the CT heart scanning artifact correction program is by the place
Reason device performs the steps of when executing
Two overlapping images in adjacent cardiac period are obtained by heart scanning；
Image registration is carried out to overlapping image and obtains optimal spatial transformation；
It is converted according to optimal spatial and two images in adjacent cardiac period is weighted acquisition consecutive image.
7. CT heart scanning artifact correction system according to claim 6, which is characterized in that the CT heart scanning artifact school
When positive program is executed by the processor, also perform the steps of
Two for extracting the adjacent cardiac period are overlapped the image information of image and respectively as reference pictures and image subject to registration, will
Image subject to registration and image subject to registration form information space, determine spatial alternation；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the first optimal spatial transformation.
8. CT heart scanning artifact correction system according to claim 7, which is characterized in that the CT heart scanning artifact school
When positive program is executed by the processor, also perform the steps of
Reference picture and image subject to registration are replaced mutually；
Image subject to registration is registrated according to spatial alternation to obtain transformed image；
Calculate the similarity measure of transformed image and reference picture；
When similarity measure is unsatisfactory for preset condition, spatial alternation is updated, and reregister；
When similarity measure meets preset condition, output the second optimal spatial transformation.
9. CT heart scanning artifact correction system according to claim 8, which is characterized in that the consecutive image are as follows:
I=w1×Tr1(I1)+w2× Tr2 (I2),
w1={ 1~0 }, w2={ 0~1 } and w1+w2=1,
Wherein, w1And w2Indicate that weighting coefficient, Tr1 indicate the transformation of the first optimal spatial, Tr2 indicates the transformation of the second optimal spatial, I1
Two images in adjacent cardiac period are respectively indicated with I2.
10. CT heart scanning artifact correction system according to claim 6, which is characterized in that the heart scanning is using more
A step-scan or helical scanning synchronous according to heartbeat phase.
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| CN116849691A (en) * | 2023-08-11 | 2023-10-10 | 南京安科医疗科技有限公司 | Method, equipment and storage medium for automatically identifying global optimal phase of cardiac CT imaging |
| CN116849691B (en) * | 2023-08-11 | 2024-03-12 | 南京安科医疗科技有限公司 | Method, equipment and storage medium for automatically identifying global optimal phase of cardiac CT imaging |
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