CN109744998A - A kind of tonometry device and tonometry method - Google Patents

A kind of tonometry device and tonometry method Download PDF

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Publication number
CN109744998A
CN109744998A CN201910193914.7A CN201910193914A CN109744998A CN 109744998 A CN109744998 A CN 109744998A CN 201910193914 A CN201910193914 A CN 201910193914A CN 109744998 A CN109744998 A CN 109744998A
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China
Prior art keywords
elasticity
cornea
pressure
film
perception
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Pending
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CN201910193914.7A
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Chinese (zh)
Inventor
吴艾久
杨思静
何兵兵
石海春
孔德润
付忠谦
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Hefei Zhongna Medical Instruments Co Ltd
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Hefei Zhongna Medical Instruments Co Ltd
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Priority to CN201910193914.7A priority Critical patent/CN109744998A/en
Publication of CN109744998A publication Critical patent/CN109744998A/en
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Abstract

The invention discloses a kind of tonometry device and tonometry methods.Tonometry device includes detection probe and detecting instrument.Detection probe includes probe distal end, elasticity perception film, transmitting medium and inductor.Groove is opened up on the end face of probe distal end;Elasticity perception film is fixed on the end face of probe distal end, and groove is sealed to an accommodating chamber;Transmitting medium is in flow-like and is housed in accommodating chamber;The induction end of inductor is inserted in accommodating chamber and thus exports inductive signal;The pressure of inductive signal characterization inductor corresponding position in accommodating chamber;Detecting instrument is for converting induction signals into corresponding pressure.It is that realization is conducted by elasticity perception film and transmitting medium indirectly to the measurement of intraocular pressure in the present invention.Transmitting medium conducts the external pressure of perception into inductor, and the external pressure of perception is converted into inductive signal.Detecting instrument receives and analyzes inductive signal.Intraocular pressure device in the present invention can simplify measurement intraocular pressure operating process.

Description

A kind of tonometry device and tonometry method
Technical field
The present invention relates to the tonometry technical field of clinical medicine application, specially a kind of tonometry device and intraocular pressure Measurement method.
Background technique
Intraocular pressure instrument is a kind of clinically used examination instrument of modern medicine, and the products application of existing a variety of different structures is pressed According to principle and method difference generally acknowledged at present, it is greatly classified into two classes:
The first kind be pressing method measurement, use the end face of a cylindric smooth specification of rigid body for test surface, external force (or Person's natural gravity) under effect, test surface is perpendicularly oriented to and is oppressed cornea centre curved surface, the curved surface is made to be pressurized in calm Then state calculates the ratio between the external force intensity applied when flattening and compression area, acquires the pressure values at compression position, this numerical value It is tested intraocular pressure value after calibrated processing.
Second class is the measurement of jet-impingement method, this is a kind of indirect measurement method;It is close in eyeball by special device Distance (5-10mm) to corneal center position spray air jet, jet pressure can controlled linear be incremented by;One group is arranged again For the light beam irradiation at corneal center position and anti-light detecting device, acquisition cornea curved surface tends to deformation area when flat position (circular diameter of deformed region);Deformation area and real-time jet pressure after record injection, to calculate cornea tested region Internal stress size, i.e., tested intraocular pressure value.
Above two method and device thereof all have the defects that certain, the first complicated for operation and Patient Experience effect is not It is good;Second of measurement accuracy be not high, usually not as quantitative detection foundation.
Summary of the invention
The purpose of the present invention is to provide a kind of tonometry device and tonometry methods, to solve existing intraocular pressure There is the not high and complicated for operation problem of measurement accuracy when measuring intraocular pressure in instrument.
To achieve the above object, the invention provides the following technical scheme: a kind of tonometry device, the tonometry dress It sets and includes:
Detection probe comprising:
Probe distal end offers a groove on end face;
Elasticity perception film, is fixed on the end face of probe distal end, and groove is sealed to an accommodating chamber;
Transmitting medium is in flow-like, and is housed in the accommodating chamber and is full of the entire accommodating chamber;And
Inductor, induction end are inserted in the accommodating chamber and thus export inductive signal, the inductive signal characterization The pressure of inductor corresponding position in the accommodating chamber;And
Detecting instrument is used to be converted to the inductive signal corresponding pressure, and by corresponding pressure with time domain song The mode of line chart is shown;The numerical value change waveform of corresponding pressure and survey in real time in the time-domain curve figure Dynamically Announce measurement process The corresponding pressure value of amount;
Wherein, for the tonometry device in measurement, the cornea centre of elasticity perception film and tested patient are flat Row is touched and is gradually pressed, until elasticity perception film is bonded with cornea;The detection probe is pressed, the canthus of tested patient is made Film curved surface is embedded into elasticity perception film by external force pressure so that elasticity perception film deformation occurs and to groove sunken inside, sense The inductive signal for answering device to export changes correspondingly;Interface two is touched between film when the cornea curved surface and elasticity of tested patient perceive When side is realized or tends to standing balance, stop pressing the detection probe, the inductive signal that the inductor exports at this time is right The pressure answered is pressure on the inside of the cornea measured needed for tested patient.
Preferably, the curve ripple deformation for being bonded tightness and being shown by time-domain curve figure of elasticity perception film and cornea Change condition prompting control operation.
Preferably, when there is fluctuation gently and tends to water steadying state in the curve waveform shown on the time-domain curve figure, Realize or tend to standing balance in the interface two sides of touching.
Preferably, the detecting instrument it is described touch interface two sides realize or tend to standing balance when, issue alarm mention Show.
Preferably, probe distal end opens up at least one injection orifice, and transmitting medium is injected into the accommodating chamber by injection orifice It is interior, while injection orifice needs to seal.
Preferably, injection orifice is closed with hot melt material.
Preferably, elasticity perception film is rubber film.
Preferably, the probe distal end is hollow structure, and bolt is isolated in setting piston-like in the probe distal end, and isolation bolt will Groove is isolated in the probe distal end and puts object slot;The induction end of inductor from put in object slot pass through isolation bolt and be housed in institute It states in accommodating chamber.
Preferably, inductor carries out data communication by optic fibre wire and the detecting instrument, wherein puts the extraction of object slot certainly Optic fibre wire object slot is put using the suit encapsulation of spring helix tube after, connection optical fiber connector forms and is connected to the detector The probe signal feeder line of device.
The present invention also proposes a kind of tonometry method, is applied to above-mentioned any tonometry device.It is described Tonometry method the following steps are included:
It touches elasticity perception film is parallel with the cornea centre of tested patient and gradually presses, until elasticity perceives Film is bonded with cornea;
The detection probe is pressed, the cornea curved surface of tested patient is made to be embedded into elastic perception by external force pressure Film so that elasticity perception film deformation occurs and to groove sunken inside, the inductive signal of inductor output changes correspondingly;
When realize or trend static(al) is flat by interface two sides for touching between the cornea curved surface and elasticity perception film of tested patient When weighing apparatus, stop pressing the detection probe;
Pressure made of the inductive signal conversion that the detecting instrument exports the inductor at this time is tested patient Pressure on the inside of the cornea of required measurement.
Compared with prior art, the beneficial effects of the present invention are:
It to the measurement of intraocular pressure is conducted and realizes indirectly by elasticity perception film and transmitting medium in the present invention.Conduction is situated between Matter is by external pressure (pressure on the inside of cornea) conduction of perception into inductor.The external pressure of perception is converted by inductor Corresponding inductive signal, and inductive signal is transmitted to detecting instrument.Detecting instrument inductive signal is successively carried out signal resolution, Photoelectric conversion, A/D converting analogue and digital electronic signal conversion and signal processing show that serialization is real eventually by display port When measurement result.When using the intraocular pressure device in the present invention, measurement intraocular pressure operating process can be simplified, and improve measurement essence Degree.
Detailed description of the invention
Fig. 1 is tonometry apparatus structure schematic diagram;
Fig. 2 is the schematic block circuit diagram of detecting instrument;
Fig. 3 is tonometry method flow chart.
In figure: probe distal end 1, elasticity perception film 11, transmitting medium 12, inductor 13, isolation bolt 14, injection orifice 15, recessed Slot 16, through-hole 17 put object slot 18, optic fibre wire 2.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
The present embodiment proposes a kind of tonometry device, is used to solve existing intraocular pressure instrument when measuring intraocular pressure, surveys The not high and complicated for operation problem of accuracy of measurement.Cornea is due to the pressure that is applied by eyes content and juice to wall of eyeball Power and canthus film tension restrict, and fill shape in sphere and show convex curvature.Relative to ambient atmosphere on the inside of cornea Environment is barotropic state.Under normal circumstances, the intraocular pressure range of people is about between 1.33-2.80kPa, i.e. 13.56- 28.55cmH2O or 9.98-21.00mmHg.
With reference to Fig. 1, measuring device includes detection probe and detecting instrument.
Detection probe is for detecting pressure on the inside of cornea.With reference to Fig. 1, detection probe can be lightweight circular tube shaped rigid body, and Its shape can be similar to common written pen.Detection probe includes probe distal end 1, elasticity perception film 11, transmitting medium 12, inductor 13 and isolation bolt 14.A groove 16 is offered on the end face of probe distal end 1.Groove 16 can be along the axial direction of probe body 2 Setting.Elasticity perception film 11 is fixed on the end face of probe distal end 1, and groove 16 is sealed to an accommodating chamber.The present embodiment In elasticity perception film 11 can be rubber film.Because elasticity perception film 11 is in ideal plane, and cornea is at convex curvature, so Elasticity perception film 11 when contact with cornea and pressing to cornea, generation deformation and to accommodating chamber sunken inside.Accommodating chamber exists When elasticity perception film 11 generates deformation, volume becomes smaller.Transmitting medium 12 is in flow-like, and is housed in accommodating chamber and full of entire Accommodating chamber.Transmitting medium 12 is flowed when elasticity perception film 11 generates deformation.In the present embodiment, ignoring transmitting medium Under the premise of 12 gravity and effect of depth, since the volume of accommodating chamber and the content of transmitting medium 12 are smaller, elasticity perception For film 11 when not contacting with cornea, the opposite pressure of the transmitting medium 12 of outside and inside is 0kPa, that is, is treated as and week Side atmospheric environment is equal with respect to pressure.In fact, the strict atmospheric pressure of earth surface definition region is 101.3kPa, or 760mmHg.Transmitting medium 12 in the present embodiment can be the little aqueous solution of viscosity.The induction end of inductor 13 is inserted in receiving In chamber and thus inductive signal is exported.The pressure of the inductive signal characterization corresponding position in accommodating chamber of inductor 13.The present embodiment In, inductor 13 can be fibre optical sensor.The photosensitive end output of fibre optical sensor is generated by pressure effect and is become by linear rule The grating signal of change.The grating signal reflects mechanism by optical fiber and is transferred to progress signal resolution and processing in detector.This reality The tonometry device for applying example can conduct the basic principle (Pascal's law) and coherent light of pressure according to fluid media (medium) indirectly Principle of interference is designed.Probe distal end 1 is hollow structure.Bolt 14 is isolated in setting piston-like in probe distal end 1.It is isolated on bolt 14 Open up a through-hole 17.The linear distance being isolated between bolt 14 and elasticity perception film 11 can be 10mm.Bolt 14 is isolated will be before probe Groove 16 is isolated in end 1 and puts object slot 18.The induction end of inductor 13 is from putting in object slot 18 across the through-hole being isolated on bolt 14 17 and be housed in accommodating chamber.
Wherein, when utilizing tonometry device to measure the intraocular pressure of tested patient, elasticity perception film 11 is with tested patient's Cornea centre is touched in parallel and gradually presses, until elasticity perception film 11 is bonded with cornea;Elasticity perception film 11 with The fitting tightness of cornea prompts control operation by detecting instrument.Pressing detection probe makes the cornea of tested patient Curved surface is embedded into elasticity perception film 11 by external force pressure so that elasticity perception film 11 deformation occurs and to 16 indent of groove It falls into, the inductive signal that inductor 13 exports changes correspondingly;When between the cornea curved surface and elasticity perception film 11 of tested patient When touching the realization of interface two sides or tending to standing balance, stop pressing detection probe;The inductive signal that inductor 13 exports at this time, Its corresponding pressure is pressure on the inside of the cornea measured needed for tested patient.
Detection probe in order to facilitate processing in some embodiments, can open up at least in the circumferential outer surface of probe distal end 1 One injection orifice 15.Injection orifice 15 is conducive to that the air inside accommodating chamber is discharged.The number of injection orifice 15 is two in the present embodiment It is a, and two injection orifices 15 are symmetricly set on the circumferential outer surface of probe distal end 1.Transmitting medium 12 is injected by injection orifice 15 Into accommodating chamber, while injection orifice 15 needs to seal.After transmitting medium 12 is injected into accommodating chamber by injection orifice 15, one Hot melt material, which can be used, in a little embodiments to close injection orifice 15.
Detecting instrument (not shown) for converting induction signals into corresponding pressure, and by corresponding pressure with when The mode of domain curve graph is shown.The numerical value change waveform and reality of corresponding pressure in the time-domain curve figure Dynamically Announce measurement process When the corresponding pressure value that measures.Time-domain curve figure is that the particle based on (time parameter) translation on plane coordinate system horizontal axis occurs The intuitive exhibition method of longitudinal wave dynamic rail mark.The effect that time-domain curve figure shows that the fluctuating change of curve and detection probe perceive is same Step, can Real-time Feedback detection probe external pressure numerical value (intraocular pressure).In general, sight can be passed through in implementing measurement process The case where examining the curve fluctuation on time-domain curve figure control measurement operation: when the curve waveform shown on the time-domain curve figure goes out When now fluctuating gently and tending to water steadying state, standing balance is realized or tended in the interface two sides of touching.And elasticity perception film 11 with the curve waveform variable condition prompt control operation for being bonded tightness and being shown by time-domain curve figure of cornea: working as bullet When sexuality knows that film 11 starts to be bonded with cornea, the curve on time-domain curve figure usually occurs curve fierceness and fluctuates and be in needle pattern It rises and falls;As pressing dynamics gradually increase when fitting operation, curve vibration frequency is gradually reduced and curve waveform tends towards stability, It jumps up until curve waveform formation one is ladder-like.When elasticity perception film 11 be bonded with cornea tightness it is moderate when, curve jumps The horizontal line risen is stablized to be translated in certain height, and height does not change with the size of pressing dynamics, and this process is held It is continuous when being longer than 2 seconds or more, that is, it is considered perceiving film and is bonded elasticity with cornea and meets measurement request.Also, in this The height value that ladder horizontal line is identified when state is tonometry value.
In the present embodiment, inductor 13 can carry out data communication by optic fibre wire 2 and detecting instrument.Wherein, it puts certainly After the optic fibre wire 2 that object slot 18 is drawn puts object slot 18 using the suit encapsulation of spring helix tube, connection optical fiber connector is the company of being formed It is connected to the probe signal feeder line of detecting instrument.Detecting instrument issues report when touching the realization of interface two sides or tending to standing balance Alert prompt.The method that voice prompting can be used in warning note is alarmed.Detecting instrument in the present embodiment is active light telecommunications Breath processing complete machine, and with a high-resolution colored display port and several different types of communication interfaces.Detecting instrument Signal resolution, photoelectric conversion, A/D converting analogue and digital electronic signal conversion and signal processing are successively carried out to inductive signal, Serialization real-time measurements are shown eventually by display port.The theory of constitution structure of detecting instrument is as shown in Figure 2.Active light Power information processing complete machine is the circuit system based on MCU microcomputer processor for maincenter, in the control of embedded application software Under system, provides and detection probe acquisition and the detection signal of the external pressure strain of perception are parsed, converted, calculated and opened up Show, output measurement data completes the functions such as information processing, and is arranged according to environmental applications, realizes data transmit-receive and shares.Work as quilt Define the end that can also become medical information system such as internet or information for hospital Intranet after an IP address Internet protocol address End equipment.
In the present embodiment, after elasticity perception film 11 touches and presses eyeball, cornea curved surface is embedding by external force pressure Enter into elasticity perception film 11.At this point, towards 16 internal direction of groove slight depression occurs for elasticity perception film 11, then cause to accommodate The volume V of chamber reduces.According to Media density formulaCalculating formula P=ρ gh with liquid pressure can export The influence of the depth h in accommodating chamber of transmitting medium 12, transmitting medium are not considered as the quality m and gh constant of transmitting medium 12 12 particle pressure P and the volume V of accommodating chamber are inversely proportional, i.e. P is increased when V reduces, until elasticity perception film 11 and cornea are bent Realize or tend to standing balance in the interface two sides of touching in face.Under this state of standing balance, the volume on the inside of cornea, i.e. eye When sphere volume is much larger than the inside volume of accommodating chamber, on the inside of the particle pressure P and cornea of the transmitting medium 12 in probe distal end 1 Pressure P ' is equal, that is, completing pressure in closed container by touching the transmitting at interface.Touch the realization of interface two sides Or when tending to standing balance, the particle pressure P of transmitting medium 12 is pressure (intraocular pressure) on the inside of cornea.
It is that the conduction realization indirectly of film 11 and transmitting medium 12 is perceived by elasticity to the measurement of intraocular pressure in the present embodiment. Transmitting medium 12 is by external pressure (pressure on the inside of cornea) conduction of perception into inductor 13.Inductor 13 will be outside perception Portion's pressure conversion is transmitted to detecting instrument at corresponding inductive signal, and by inductive signal.Detecting instrument to inductive signal successively Signal resolution, photoelectric conversion, A/D converting analogue and digital electronic signal conversion and signal processing are carried out, eventually by display end Mouth shows serialization real-time measurements.When using the intraocular pressure device in the present embodiment, measurement intraocular pressure can be simplified and operated Journey, and improve measurement accuracy.
Embodiment 2
The present embodiment provides a kind of tonometry methods, are applied to tonometry device described in embodiment 1.With reference to Fig. 3, tonometry method the following steps are included:
It touches elasticity perception film 11 is parallel with the cornea centre of tested patient and gradually presses, up to elastic sensation Know that film 11 is bonded with cornea;
Pressing detection probe makes the cornea curved surface of tested patient be embedded into elasticity perception film 11 by external force pressure, So that elasticity perception film 11 deformation occurs and to 16 sunken inside of groove, the inductive signal that inductor 13 exports changes correspondingly;
When static(al) is realized or tended in the interface two sides of touching between the cornea curved surface and elasticity perception film 11 of tested patient When balance, stop pressing detection probe;
Pressure made of the inductive signal conversion that detecting instrument exports inductor 13 at this time is survey needed for tested patient Pressure on the inside of the cornea of amount.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (10)

1. a kind of tonometry device, which is characterized in that the tonometry device includes:
Detection probe comprising:
Probe distal end (1) offers a groove (16) on end face;
Elasticity perception film (11), is fixed on the end face of probe distal end (1), and groove (16) is sealed to an accommodating chamber;
Transmitting medium (12) is in flow-like, and is housed in the accommodating chamber and is full of the entire accommodating chamber;And
Inductor (13), induction end are inserted in the accommodating chamber and thus export inductive signal, the inductive signal characterization The pressure of inductor (13) corresponding position in the accommodating chamber;And
Detecting instrument is used to being converted to the inductive signal into corresponding pressure, and by corresponding pressure with time-domain curve figure Mode show;The numerical value change waveform of corresponding pressure and real-time measurement in the time-domain curve figure Dynamically Announce measurement process Corresponding pressure value;
Wherein, for the tonometry device in measurement, the cornea centre of elasticity perception film (11) and tested patient are flat Row is touched and is gradually pressed, until elasticity perception film (11) is bonded with cornea;The detection probe is pressed, makes tested patient's Cornea curved surface is embedded into elasticity perception film (11) by external force pressure so that elasticity perception film (11) deformation occurs and to recessed The inductive signal of slot (16) sunken inside, inductor (13) output changes correspondingly;When the cornea curved surface and elastic sensation of tested patient Know between film (11) when touching interface two sides and realizing or tend to standing balance, stop pressing the detection probe, the induction The inductive signal that device (13) exports at this time, corresponding pressure are pressure on the inside of the cornea measured needed for tested patient.
2. tonometry device according to claim 1, which is characterized in that elasticity perception film (11) is bonded with cornea The curve waveform variable condition prompt control operation that tightness is shown by time-domain curve figure.
3. tonometry device according to claim 1, which is characterized in that the curve ripple shown on the time-domain curve figure When shape fluctuation occurs gently and tends to water steadying state, standing balance is realized or tended in the interface two sides of touching.
4. tonometry device according to claim 1, which is characterized in that the detecting instrument touches interface two described When side is realized or tends to standing balance, warning note is issued.
5. tonometry device according to claim 1, which is characterized in that probe distal end (1) opens up at least one injection Hole (15), transmitting medium (12) is injected into the accommodating chamber by injection orifice (15), while injection orifice (15) needs to seal.
6. tonometry device according to claim 5, which is characterized in that closed injection orifice (15) with hot melt material.
7. tonometry device according to claim 1, which is characterized in that elasticity perception film (11) is rubber film.
8. tonometry device according to claim 1, which is characterized in that the probe distal end (1) is hollow structure, institute It states setting piston-like in probe distal end (1) and bolt (14) is isolated, isolation bolt (14) will isolate groove in the probe distal end (1) (16) it and puts object slot (18);From putting, object slot (18) is interior to be housed in the receipts across isolation bolt (14) to the induction end of inductor (13) In cavity.
9. tonometry device according to claim 8, which is characterized in that inductor (13) by optic fibre wire (2) with The detecting instrument carries out data communication, wherein the optic fibre wire (2) for putting object slot (18) extraction certainly is set with using spring helix tube After object slot (18) are put in encapsulation, connection optical fiber connector forms the probe signal feeder line for being connected to the detecting instrument.
10. a kind of tonometry method is applied to tonometry device as claimed in any of claims 1 to 9, It is characterized in that, the tonometry method the following steps are included:
It touches elasticity perception film (11) is parallel with the cornea centre of tested patient and gradually presses, until elasticity perceives Film (11) is bonded with cornea;
The detection probe is pressed, the cornea curved surface of tested patient is made to be embedded into elasticity perception film by external force pressure (11), so that elasticity perception film (11) deformation occurs and to groove (16) sunken inside, the inductive signal of inductor (13) output with Change;
When realize or trend static(al) is flat by interface two sides for touching between the cornea curved surface and elasticity perception film (11) of tested patient When weighing apparatus, stop pressing the detection probe;
Pressure made of the inductive signal conversion that the detecting instrument exports the inductor (13) at this time is tested patient Pressure on the inside of the cornea of required measurement.
CN201910193914.7A 2019-03-14 2019-03-14 A kind of tonometry device and tonometry method Pending CN109744998A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4729378A (en) * 1985-11-26 1988-03-08 Interzeag Ag Apparatus for ascertaining the pressure in a plenum chamber
US20020193675A1 (en) * 2001-06-13 2002-12-19 Sis Ag Surgical Instrument Systems Devices and methods for determining the inner pressure of an eye
JP2003079582A (en) * 2001-09-10 2003-03-18 Nidek Co Ltd Non-contact tonometer
JP2004267299A (en) * 2003-03-05 2004-09-30 Univ Nihon Intraocular pressure examination device
JP2005087549A (en) * 2003-09-18 2005-04-07 Canon Inc Non-contact tonometer
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