CN109723890B - Electromagnetic micro-fluidic valve - Google Patents
Electromagnetic micro-fluidic valve Download PDFInfo
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- CN109723890B CN109723890B CN201910065107.7A CN201910065107A CN109723890B CN 109723890 B CN109723890 B CN 109723890B CN 201910065107 A CN201910065107 A CN 201910065107A CN 109723890 B CN109723890 B CN 109723890B
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Abstract
An electromagnetic micro-fluidic valve comprises a micro-fluidic chip and a valve body; the micro-fluidic chip is provided with a micro-channel; the valve body comprises a coil and a spring which are fixedly arranged, a movable armature is movably arranged on the inner side of the coil, one end of the movable armature is connected with the spring, the other end of the movable armature is in driving connection with a piston, a plug is fixedly arranged on the piston, faces the microfluidic chip and is matched with the microfluidic channel. The invention provides an electromagnetic micro-fluidic valve which is strong in universality, simple in structure, reusable, sensitive in action and good in isolation effect.
Description
Technical Field
The invention relates to the technical field of microfluidics, in particular to an electromagnetic microfluidic valve.
Background
Microfluidics refers to the science and technology involved in systems that process or manipulate tiny fluids (nanoliters to attoliters in volume) using microchannels (tens to hundreds of microns in size), and is an emerging interdiscipline that involves chemical, fluid physics, microelectronics, new materials, biology, and biomedical engineering. It is widely applied to the fields of cell analysis, nucleic acid extraction, nucleic acid amplification, biochemical detection, immunodetection, and the like. The micro-fluidic has the characteristics of miniaturization, integration and the like and is mainly realized through a micro-fluidic chip. And the precise flow of the liquid in the flow channel of the microfluidic chip is mainly realized by a valve.
The prior common micro-fluidic valve has the advantages that a back membrane built with a micro-fluidic chip is expanded and contracted by inflating and deflating gas so as to control the flow of liquid in a flow channel; a paraffin valve which is specially used for liquid and driven by centrifugal force; the paraffin hot melting valve is formed by directionally heating a valve part by utilizing heat sources such as laser and the like to be dissolved and opened; a mechanism is designed, and a certain component of the mechanism extends out and retracts through the positive and negative rotation of a motor, so that a back membrane built with a micro-fluidic chip is extruded, and the mechanical valve is used for controlling liquid in a flow channel to accurately flow. Some valves need a special gas source, some valves can only be used for a certain microfluidic device, the universality is limited, some valves can only be used once and cannot be operated repeatedly, and the mechanism is complex, so that the whole microfluidic platform is too large, and the processing, assembly and use are inconvenient.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides the electromagnetic micro-fluidic valve which is strong in universality, simple in structure, sensitive in action and good in isolation effect, and can be used repeatedly.
In order to achieve the purpose, the invention adopts the specific scheme that: an electromagnetic micro-fluidic valve comprises a micro-fluidic chip and a valve body; the micro-fluidic chip is provided with a micro-channel; the valve body comprises a coil and a spring which are fixedly arranged, a movable armature is movably arranged on the inner side of the coil, one end of the movable armature is connected with the spring, the other end of the movable armature is in driving connection with a piston, a plug is fixedly arranged on the piston, faces the microfluidic chip and is matched with the microfluidic channel.
As a preferable scheme, a back membrane is arranged between the microfluidic chip and the piston, and the back membrane and the microfluidic chip are parallel to each other.
As a preferred scheme, the piston type air conditioner further comprises a fixedly arranged mounting platform, a track is formed in the mounting platform, and the piston is arranged in the track in a sliding mode.
As a preferable scheme, the track comprises a first cylindrical section, a conical transition section and a second cylindrical section which are sequentially communicated, the diameter of the first cylindrical section is larger than that of the second cylindrical section, the large end of the conical transition section is communicated with the first cylindrical section, the small end of the conical transition section is communicated with the second cylindrical section, and the piston is arranged in the second cylindrical section in a sliding mode.
As a preferred scheme, the valve body comprises a static armature, the static armature is in threaded connection with one end of the first cylindrical section, which is back to the microfluidic chip, the coil is wound around the periphery of the static armature, a channel is formed in the center of the static armature, a movable armature connecting rod is arranged in the channel in a sliding manner, one end of the movable armature connecting rod is fixedly connected with the movable armature, and the other end of the movable armature connecting rod is fixedly connected with the piston.
As a preferred scheme, a coil framework is fixedly sleeved on the static armature, and the coil is wound on the coil framework.
As a preferred scheme, the valve body comprises a shell, the static armature stretches into the shell, the coil, the dynamic armature, the coil framework and the spring are all arranged in the shell, and a through hole is formed in the shell.
As a preferable scheme, a flexible cushion is fixedly arranged in the shell, and the spring is fixedly connected with the flexible cushion.
As a preferred scheme, the shell is detachably connected with an end cover, and the flexible pad is fixedly arranged on the inner side of the end cover.
Has the advantages that: the plug is used as the smallest component in the whole valve, has simple structure, is easy to process and can be repeatedly used, and on the basis, the plug controls the smooth or cut-off of a micro-channel by using the mode of pushing the plug to move by magnetic force, and has sensitive action and good isolation effect.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
Reference numerals: 1-mounting platform, 2-piston, 3-movable armature connecting rod, 4-back membrane, 5-microfluidic chip, 6-positioning lock nut, 7-static armature, 8-coil, 9-movable armature, 10-shell, 11-coil framework, 12-spring, 13-flexible pad, 14-end cover, 15-microchannel, 16-plug, 17-conical transition section and 18-through hole.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, an electromagnetic microfluidic valve includes a microfluidic chip 5 and a valve body.
The micro-fluidic chip 5 is provided with a micro-channel 15.
The valve body comprises a coil 8 and a spring 12 which are fixedly arranged, a movable armature 9 is movably arranged on the inner side of the coil 8, one end of the movable armature 9 is connected with the spring 12, the other end of the movable armature 9 is connected with a piston 2 in a driving mode, a plug 16 is fixedly arranged on the piston 2, and the plug 16 faces the microfluidic chip 5 and is matched with a micro-channel 15.
When the micro-channel 15 needs to be cut off to block liquid from flowing, power is supplied to the coil 8, a magnetic field is generated in the coil 8, the movable armature 9 moves towards the micro-fluidic chip 5 under the action of the magnetic field, the spring 12 is stretched and the piston 2 is pushed to move synchronously in the process until the plug 16 extends into the micro-channel 15 to cut off the micro-channel 15.
When the liquid flow needs to be recovered, the power supply is cut off to ensure that the coil 8 loses power, the magnetic field disappears, the spring 12 rebounds, the movable armature 9 is pulled to be away from the microfluidic chip 5, the movable armature 9 pulls the piston 2 and the plug 16 to move, and finally the plug 16 is moved out of the microfluidic channel 15 to recover the liquidity of the microfluidic channel 15, so that the liquid flows smoothly.
The plug 16 of the invention is used as the smallest part in the whole valve, has simple structure, easy processing and can be repeatedly used, on the basis, the invention controls the smooth or cut-off of the micro-channel 15 by using the way of pushing the plug 16 to move by magnetic force, and has sensitive action and good isolation effect.
Further, a back membrane 4 is arranged between the microfluidic chip 5 and the piston 2, and the back membrane 4 and the microfluidic chip 5 are parallel to each other. The elastic resistance of the back membrane 4 needs to be overcome in the process that the plug 16 moves towards the microfluidic chip 15, the back membrane 4 can be extruded into the microchannel 15, and a gap possibly existing between the plug 16 and the inner wall of the microchannel 15 is completely sealed, so that the effect of cutting off the microchannel 15 is further improved while the airtightness of the microchannel is ensured.
In order to accurately control the directions of the piston 2 and the plug 16 and ensure that the plug 16 can accurately extend into the micro flow channel 15, the valve further comprises a fixedly arranged mounting platform 1, a track is arranged on the mounting platform 1, and the piston 2 is arranged in the track in a sliding manner.
Furthermore, the track comprises a first cylindrical section, a conical transition section 17 and a second cylindrical section which are sequentially communicated, the diameter of the first cylindrical section is larger than that of the second cylindrical section, the large end of the conical transition section 17 is communicated with the first cylindrical section, the small end of the conical transition section 17 is communicated with the second cylindrical section, and the piston 2 is arranged in the second cylindrical section in a sliding mode. Through the transition of the conical transition section 17, the size of the movable armature 9 and other parts can be properly increased on the premise of guiding the piston 2, and the processing difficulty is reduced.
The valve body further comprises a static armature 7, the static armature 7 is in threaded connection with one side of the first cylindrical section of the mounting platform 1, which is back to the microfluidic chip 5, a coil 8 is wound on the periphery of the static armature 7, a channel is formed in the center of the static armature 7, a movable armature connecting rod 3 is arranged in the channel in a sliding mode, one end of the movable armature connecting rod 3 is fixedly connected with a movable armature 9, and the other end of the movable armature connecting rod 3 is fixedly connected with the piston 2. The static armature 7 can strengthen the magnetic field and can connect the valve body and the mounting platform 1 into a whole. The static armature 7 is also fixed in position by a positioning lock nut 6.
Furthermore, a coil framework 11 is fixedly sleeved on the static armature 7, and the coil 8 is wound on the coil framework 11. The coil framework 8 can isolate the movable armature 9 from the coil 8 and conveniently fix the coil 8.
The valve body further comprises a shell 10, the static armature 7 extends into the shell 10, the coil 8, the movable armature 9, the coil framework 11 and the spring 12 are all arranged in the shell 10, a through hole 18 is formed in the shell 10, and the shell 10 plays a role in protecting and avoiding being corroded by the external environment.
When the movable armature 9 is reset under the action of the spring 12, due to inertia, the movable armature may possibly impact the housing 10, and the housing 10 is easily damaged after long-term use, so that the flexible cushion 13 is fixedly arranged in the housing 10, the spring 12 is fixedly connected with the flexible cushion 13, and the flexible cushion 13 can buffer the movable armature 9. The specific setting mode of the flexible mat 13 is as follows: the housing 10 is detachably connected with an end cover 14, and the flexible pad 13 is fixedly arranged at the inner side of the end cover 14.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (7)
1. An electromagnetic microfluidic valve characterized by: comprises a micro-fluidic chip (5) and a valve body;
the micro-fluidic chip (5) is provided with a micro-channel (15);
the valve body comprises a coil (8) and a spring (12) which are fixedly arranged, a movable armature (9) is movably arranged on the inner side of the coil (8), one end of the movable armature (9) is connected with the spring (12), the other end of the movable armature (9) is connected with a piston (2) in a driving mode, a plug (16) is fixedly arranged on the piston (2), and the plug (16) faces the microfluidic chip (5) and is matched with the microchannel (15);
the piston type piston engine is characterized by further comprising a fixedly arranged mounting platform (1), wherein a track is formed in the mounting platform (1), and the piston (2) is arranged in the track in a sliding manner;
the track comprises a first cylindrical section, a conical transition section (17) and a second cylindrical section which are sequentially communicated, the diameter of the first cylindrical section is larger than that of the second cylindrical section, the large end of the conical transition section (17) is communicated with the first cylindrical section, the small end of the conical transition section (17) is communicated with the second cylindrical section, and the piston (2) is arranged in the second cylindrical section in a sliding mode.
2. The electromagnetic microfluidic valve of claim 1, wherein: a back membrane (4) is arranged between the micro-fluidic chip (5) and the piston (2), and the back membrane (4) and the micro-fluidic chip (5) are parallel to each other.
3. The electromagnetic microfluidic valve of claim 1, wherein: the valve body includes static armature (7), static armature (7) with the dorsad of first cylinder section the one end threaded connection of micro-fluidic chip (5), coil (8) are around establishing in the week side of static armature (7), and the center department of static armature (7) has seted up the passageway, and it is provided with to slide in the passageway and moves armature connecting rod (3), move the one end of armature connecting rod (3) with move armature (9) fixed connection, move the other one end of armature connecting rod (3) with piston (2) fixed connection.
4. The electromagnetic microfluidic valve of claim 3, wherein: the fixed cover is equipped with coil skeleton (11) on static armature (7), coil (8) are around establishing on coil skeleton (11).
5. The electromagnetic microfluidic valve of claim 4, wherein: the valve body comprises a shell (10), the static armature (7) extends into the shell (10), the coil (8), the dynamic armature (9), the coil framework (11) and the spring (12) are all arranged in the shell (10), and a through hole (18) is formed in the shell (10).
6. The electromagnetic microfluidic valve of claim 5, wherein: the shell (10) is internally and fixedly provided with a flexible pad (13), and the spring (12) is fixedly connected with the flexible pad (13).
7. The electromagnetic microfluidic valve of claim 6, wherein: the shell (10) is detachably connected with an end cover (14), and the flexible pad (13) is fixedly arranged on the inner side of the end cover (14).
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CN201910065107.7A CN109723890B (en) | 2019-01-23 | 2019-01-23 | Electromagnetic micro-fluidic valve |
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CN201910065107.7A CN109723890B (en) | 2019-01-23 | 2019-01-23 | Electromagnetic micro-fluidic valve |
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CN109723890A CN109723890A (en) | 2019-05-07 |
CN109723890B true CN109723890B (en) | 2020-07-14 |
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CN110684656A (en) * | 2019-06-29 | 2020-01-14 | 东南大学 | Integrated micro-fluidic chip platform based on SERS technology |
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US6405757B1 (en) * | 2000-08-01 | 2002-06-18 | Humphrey Products Company | Low power solenoid valve assembly |
CN2503286Y (en) * | 2001-09-07 | 2002-07-31 | 宜兴市四通塑粉有限公司 | Flow control magnetic valve |
CN2592972Y (en) * | 2002-10-11 | 2003-12-17 | 张曙东 | Normal-open electromagnetic valve |
JP2005291383A (en) * | 2004-03-31 | 2005-10-20 | Nissin Kogyo Co Ltd | Normally closed solenoid valve |
CN104565501B (en) * | 2015-01-20 | 2016-12-07 | 重庆科技学院 | A kind of micro-fluidic three-way magnetic valve and using method |
CN104896191A (en) * | 2015-05-08 | 2015-09-09 | 沈阳航空航天大学 | Paraffin valve capable of being repeatedly used |
CN206206740U (en) * | 2016-10-11 | 2017-05-31 | 昆明理工大学 | A kind of Electromagnetic Drive fluid miniature valve |
CN106763991B (en) * | 2016-11-22 | 2020-04-24 | 上海空间推进研究所 | Miniature electromagnetic type proportional flow control valve |
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