CN109718433B

CN109718433B - Inhalation atomizer kit

Info

Publication number: CN109718433B
Application number: CN201711051268.8A
Authority: CN
Inventors: 李昌辉; 何明波; 朱雪冰
Original assignee: Chia Tai Tianqing Pharmaceutical Group Co Ltd
Current assignee: Chia Tai Tianqing Pharmaceutical Group Co Ltd
Priority date: 2017-10-31
Filing date: 2017-10-31
Publication date: 2024-02-20
Anticipated expiration: 2037-10-31
Also published as: CN109718433A

Abstract

The utility model belongs to the field of medical equipment, particularly, relate to an inhalation type atomizer external member, the interior passway of this application is infiltrated outside air admission passageway through utilizing the interior liquid drop that aerosol gathers into in the atomizing chamber to form the liquid film in order to be automatic, has effectively reduced the interior aerosol loss of atomizing chamber, in addition, the drainage line that sets up in the atomizing chamber has not only reduced the residual rate of inner wall liquid medicine, still makes the process that forms the liquid film automatically become more high-efficient controllable.

Description

Inhalation atomizer kit

Technical Field

The present invention relates to an inhalation nebulizer kit, and more particularly to a continuous operation inhalation nebulizer kit.

Background

Inhalation nebulizers deliver a therapeutically effective amount of a drug by dispersing an aqueous solution or suspension of the drug into a drug-containing aerosol of a readily inhalable size suspended in a gas, deposited on the respiratory tract and/or lungs by inhalation by the patient, are currently widely used in the treatment of a variety of respiratory diseases, particularly pediatric and geriatric patients with asthma or COPD, and those not suitable for other inhalation formulations.

Inhalation type atomizers are many, including jet atomizers, ultrasonic atomizers, vibrating screen atomizers, etc., and some new atomizers are also under study or in clinical trials. The medical nebulizers, which are continuously operated as nebulizers, ultrasonic nebulizers and vibrating screen nebulizers, operate not only when the patient inhales, but also when the patient exhales, the aerosol generated by the aerosol generator fills the nebulizing chamber, and is actually inhaled by the patient only during the inhalation phase, while most of the aerosol is condensed into droplets on the inner wall of the nebulizer and flows back into the reservoir.

It has been found that opening the external air inlet passage in the housing of the nebulizing chamber is beneficial in enhancing the nebulization effect by allowing the external air to be guided into the nebulizing chamber by means of the air flow generated by the inhalation of the patient, allowing the air to flow according to the function of the nebulizer and entrain the aerosol into the patient. For example, chinese patent document CN103041480a discloses an atomizing device with improved air flow resistance, wherein an external air inlet path OP1 can guide an air flow to the vicinity of an aerosol generating portion, so that an aerosol generated by the aerosol generating portion can flow more smoothly toward an opening OP 4.

However, while opening the external air inlet passage on the housing of the nebulizing chamber, problems of aerosol loss may occur due to the continuous operation of the nebulizer and the generation of aerosol in the nebulizing chamber, particularly when the patient exhales.

US20110209700 discloses an inhalation type nebulizing device provided with a valve which is provided with a gas valve and a breathing valve at different locations, the gas valve allowing air to enter the nebulizing chamber from the outside when the patient inhales and closing when exhaling. However, the valve needs to be periodically disassembled, cleaned and reinstalled, which causes inconvenience to use, and the appliance has a complex structure and high cost.

In addition to controlling the escape of aerosol, researchers have attempted to limit aerosol generation to some or all of the inhalation phases, such as manually interrupting aerosol generation, or may automatically control aerosol generation by detecting patient respiration. Both of these situations are problematic in that manual control of aerosol generation places additional burden on the patient, and automatic control of aerosol generation requires significant technical expenditure, but may not be of corresponding benefit.

Disclosure of Invention

The present invention aims to provide a continuously operating inhalation nebulizer kit, which solves or reduces the problems encountered in the prior art. In order to achieve the above object, the present invention provides the following technical solutions:

a continuous operation inhalation nebulizer kit, comprising:

an atomizing chamber defined by the housing and including a lower reservoir, an upper cavity, and an aerosol generator, the cavity having a longitudinal wall provided by the atomizing chamber housing;

the external air inlet channel comprises an external channel port, an internal channel port and a channel body;

the mist outlet channel extends outwards from the atomizing chamber shell and is communicated with the cavity;

the inner passage opening is arranged to be easy to form a liquid film structure and is arranged on a sliding path of liquid drops on the longitudinal wall.

Preferably, the inner passage opening is provided as an aperture or slit.

Preferably, the inner passage opening is lower than the outer passage opening and/or the passage body.

Preferably, the top end of the longitudinal wall is connected to the other housing of the atomizing chamber, and the part of the housing providing the longitudinal wall has a thickness sufficient to enable the outside air inlet passage to be arranged therein in a hollow manner and to extend from the outer passage opening, the passage body and the inner passage opening from top to bottom.

Preferably, the longitudinal wall is a side wall of the cavity of the atomizing chamber, and the inner passage opening is arranged on the side wall of the cavity of the atomizing chamber.

Preferably, the external air inlet channels are plural and are arranged around the side wall.

Preferably, drainage lines for promoting the gathering and sliding of liquid drops on the surface of the longitudinal wall are arranged on the longitudinal wall, the drainage lines are longitudinally distributed on the whole, and the inner passage opening is arranged on a drainage path of the drainage lines.

Further preferably, the cross section of the drainage wire is in a groove shape or a ridge shape, and still further preferably in a groove shape.

Further preferably, the shape of the cross section of the drainage wire is selected from arc, square, triangle or trapezoid.

Further preferably, the width of the drainage lines is 0.1-3.0mm, and the interval between the drainage lines is 0-15.0mm. Still more preferably, the width of the drainage lines is 0.3-1.5mm, and the interval between the drainage lines is 1.0-6.0mm.

Preferably, the continuous operation type suction atomizer is a spray atomizer, the atomization chamber is cylindrical as a whole, the aerosol generator protrudes upwards from the middle area of the liquid storage part into the cavity, and the aerosol generator is arranged to continuously convert the liquid in the liquid storage part into aerosol and spray the aerosol into the cavity.

It is further preferred that the housing of the atomizing chamber extends from the top of the cavity into the cavity at the lower side thereof a tubular structure surrounding the aerosol generator and having an open lower side, one side thereof facing the aerosol generator forms a longitudinal wall, the other side thereof forms a sandwiching cavity having an open lower side with the side wall of the cavity, the housing of the tubular structure has a sufficient thickness so that an external air inlet passage is provided therein in a hollow manner and extends downward from an external passage opening at the top thereof, and the internal passage opening is provided on the longitudinal wall surrounding the aerosol generator.

Still further preferably, the external air inlet passage is provided in plurality and is annularly arranged along the longitudinal wall.

Still more preferably, drainage lines for promoting the gathering and sliding of the surface liquid drops are arranged on the longitudinal wall, the drainage lines are longitudinally distributed on the whole, and the inner passage opening is arranged on a drainage path of the drainage lines.

Further preferably, the shell of the atomization chamber extends from the top of the cavity to the cavity at the lower side to form a cylindrical structure which surrounds the aerosol generator and is open at the lower side, one side of the cylindrical structure facing the aerosol generator forms a longitudinal wall, the other side of the cylindrical structure and the side wall of the cavity form a clamping cavity with open lower side, the shell of the cylindrical structure has enough thickness so that the external air inlet channel can be arranged in the hollow mode, the cylindrical structure is provided with a diversion channel penetrating through two sides of the cylindrical structure, the diversion channel is arranged to drain liquid drops positioned at one side of the longitudinal wall into the diversion channel, and the external air inlet channel extends downwards from an external channel opening at the top of the cylindrical structure to the diversion channel so that the internal channel opening is arranged in the diversion channel.

Still more preferably, the opening of the flow guiding channel at one side of the longitudinal wall is square or oval, and its height is preferably 0.3-3.0mm, still more preferably 0.8-2.0mm, and its width is preferably 2.0-10.0mm, still more preferably 4.0-8.0mm.

Still more preferably, the lower edge of the opening of the flow guide passage on the side of the cavity is not higher than the lower edge of the opening on the side of the longitudinal wall, and the upper edge of the opening on the side of the cavity is not higher than the upper edge of the opening on the side of the longitudinal wall.

Still more preferably, the lower edge of the opening of the flow guide passage on the side of the cavity is not higher than the lower edge of the opening on the side of the longitudinal wall, and the upper edge of the opening on the side of the cavity is lower than the upper edge of the opening on the side of the longitudinal wall.

Still more preferably, the longitudinal wall is provided with drainage lines for promoting the gathering and sliding of liquid drops on the surface of the drainage lines, the drainage lines are longitudinally distributed as a whole, and an opening of the drainage channel at one side of the clamping cavity is positioned on a drainage path of the drainage lines.

Still more preferably, the mist outlet channel is formed at the top of the cavity and is communicated with the cavity area surrounded by the longitudinal wall.

Preferably, the continuous operation type inhalation nebulizer kit further comprises an interface member including an engagement portion for engaging the mist outlet channel, a mouthpiece for the patient, and an exhalation port therebetween.

Further preferably, an elastic valve is further arranged between the breathing hole and the connecting part of the interface piece, and the elastic valve seals the tube body by means of self elastic force in a natural state or when the patient exhales, and is opened to ventilate the tube body when the patient inhales.

In another aspect, the present invention provides a method of preventing escape of aerosol from an external air inlet passage of a continuous operation type inhalation atomizer, comprising:

(1) A longitudinal wall is arranged in an inner cavity of an atomization chamber of the atomizer, so that aerosol can adhere to the longitudinal wall and gather into liquid drops to slide;

(2) The inner passage opening of the external air inlet passage is arranged to be in a slit or pore shape, is easy to form a liquid film structure, and is arranged on the sliding path of the liquid drop on the longitudinal wall, so that the liquid drop passes through and infiltrates the inner passage opening to form a liquid film for blocking the inner passage opening;

(3) An exhalation port is provided on the mouthpiece of the nebulizer so that the patient's expiratory airflow may be expelled through the exhalation port.

Preferably, the continuous operation type suction atomizer is an injection atomizer.

According to the continuously working type suction atomizer kit, the liquid drops aggregated by the aerosol in the atomization chamber are utilized to infiltrate the inner channel opening of the external air inlet channel to automatically form the liquid film, so that the loss of the aerosol in the atomization chamber is effectively reduced, in addition, the drainage line arranged in the atomization chamber not only reduces the residual rate of the liquid medicine on the inner wall, but also enables the process of automatically forming the liquid film to be more efficient and controllable.

Drawings

FIG. 1 shows a block diagram of an aerosol inhaler kit according to the present invention

FIG. 2 shows a block diagram of another aerosol inhaler kit according to the present invention

FIG. 3 shows a block diagram of another aerosol inhaler kit according to the present invention

FIG. 4 shows a block diagram of another aerosol inhaler kit according to the present invention

FIG. 5 shows a block diagram of another aerosol inhaler kit according to the present invention

Fig. 6 shows a cross-sectional view of the external air inlet channel of the aerosol inhaler kit of fig. 1-5

FIG. 7 shows an enlarged partial view of a certain inner passage opening of the aerosol inhaler kit of FIG. 3

FIG. 8 shows an enlarged partial view of a certain inner passage opening of the aerosol inhaler kit of FIG. 4

FIG. 9 is a cross-sectional view taken along line A-A of the region near the inner port shown in FIG. 7

FIG. 10 is a cross-sectional view taken along line A-A of the region near the inner port shown in FIG. 8

FIG. 11 shows a block diagram of a mouthpiece suitable for use in an aerosol inhaler of the present invention

Fig. 12 shows a bottom view of the cylindrical structure of the aerosol inhaler kit of fig. 5

Detailed Description

As shown in fig. 1, an embodiment of a continuous operation type inhalation atomizer kit according to the present invention comprises: (a) An atomising chamber 1 defined by the housing and comprising a lower reservoir 11, an upper cavity 12, and an aerosol generator 13 arranged to convert liquid in the reservoir 11 into an aerosol; (b) An external air inlet passage 2 which communicates with the external environment of the atomizing chamber 1 and the cavity 12, and which includes an external passage port 21 located outside the atomizing chamber 1, an internal passage port 22 located on one side of the cavity, and a passage body 23; (c) A mist outlet channel 3 which extends outwards from the shell of the atomizing chamber 1 and is communicated with the cavity 12. The housing of the atomizing chamber 1 provides a longitudinal wall 14 which can be contacted with the aerosol in the cavity 12, so that the aerosol can adhere to the longitudinal wall 14 and gather into a liquid drop to slide, the inner passage opening 22 is arranged in a slit-shaped liquid film forming structure and is arranged on the sliding path of the liquid drop on the longitudinal wall 14, and a liquid film for blocking the inner passage opening 22 is formed when the liquid drop passes through and infiltrates the inner passage opening 22.

The concentration of the aerosol in the atomizing chamber 1 of the embodiment changes along with the respiration of the user, and at the end of inhalation, the concentration of the aerosol in the atomizing chamber 1 rises and adheres to the inner wall of the cavity 12 to form liquid drops, the liquid drops slide into the liquid storage part 11 to be continuously atomized into the aerosol, and the aerosol adheres to the cavity 12 to form liquid drops to slide, so that the reciprocating cycle is realized. In the embodiment, the inner passage opening 22 of the external air inlet passage 2 is provided with a gap or pore structure, so that when the liquid drops on the longitudinal wall 14 slide down and pass through the inner passage opening 22, the gap or pore-shaped inner passage opening 22 is adhered and blocked by surface tension;

the longitudinal wall of the cavity is a surface which is distributed longitudinally in the cavity as a whole and contacts with aerosol, including but not limited to a side wall of the cavity, a channel wall or a baffle plate which guides the airflow in the cavity, for example, the longitudinal wall can be the surface of an inner wall of an atomization chamber and/or an air supply pipe of US 6513727B 1, US 7131440B 2 or US5312046A1, the inner wall of an atomization chamber of CN201996938U, CN106029139A, CN104010684a, the inner wall of an atomization chamber of CN102844067A, CN101277731a and/or a baffle plate surface for forming a flow path, the inner wall of an atomization chamber of CN104023773a and a surface of a spray discharge channel. The longitudinal direction may be vertical or substantially vertical, or may be a non-perfect vertical direction with a certain inclination, for example, referring to fig. 2, and as a variant of this embodiment, the lower portion of the longitudinal wall 14 is an inclined plane with a certain inclination, and the inner passage opening 22 is formed on the inclined plane.

Wherein, the sliding path refers to an area that may be passed by the aerosol when the aerosol adheres to the longitudinal wall and gathers into droplets to slide down along the longitudinal wall 14, and includes, but is not limited to, a surface of the longitudinal wall 14, a lower edge of the longitudinal wall 14, a notch formed on a surface of the longitudinal wall 14, or a channel penetrating the longitudinal wall 14, etc., for example, referring to fig. 5 and 12, it is seen that the inner channel opening 22 is disposed at the lower edge of the longitudinal wall 14.

Wherein the liquid droplets form a liquid film at the inner passage opening of a film-forming structure, typically a smaller pore or slit structure of caliber, including but not limited to small holes, slits or grids, etc., by means of surface tension. Furthermore, it is advantageous for the liquid film-forming structure to have a sufficient thickness (length) for forming a liquid film or liquid mass, for example by providing the inner passage opening with a length of pores (elongated tubular shape) which, when encountering a droplet, can create a capillary phenomenon, absorb the liquid and form a liquid mass blocking the inner passage opening.

Further, in one embodiment, as shown in fig. 1, an aerosol generator 13 is located in the middle region of the reservoir 11 and protrudes into the upper cavity 12, and is arranged to convert the liquid in the reservoir 11 into aerosol and spray into said cavity 12.

The inhalation atomizer kit of the embodiment is a jet atomizer, the aerosol generator of the inhalation atomizer kit is a common atomizer atomization structure in the prior art, and comprises a compressed air inlet pipe extending upwards from the lower side, and the tail end of the upper part of the compressed air inlet pipe forms an air injection hole in the cavity of the atomization chamber; and a flow path forming body which is mounted on the compression ingress pipe in a covering mode, and is provided with spray holes at the positions of the spray holes, and the flow path forming body is communicated with the spray holes and the liquid storage part; in addition, a blocking member is included above the spray orifice. The basic principle is Bernoulli's principle, compressed air is utilized to form high-speed air flow through a fine pipe orifice, the generated negative pressure drives liquid in a liquid storage part to be sprayed onto a barrier, and liquid drops are splashed to the periphery under high-speed impact to be changed into mist particles to be sprayed out from an air outlet pipe, so that effective inhalation treatment is realized.

Further, in one embodiment, as shown in fig. 1 and 6, the top end of the housing portion where the longitudinal wall 14 is located is connected to the other housing portion of the atomizing chamber 1, and has a sufficient thickness so that the outside air inlet channel 2 can be disposed therein in a hollow manner, and the outside air inlet channel 2 extends from the outside channel port 21, the channel body 23, and the inside channel port 22 from top to bottom.

The housing in which the longitudinal wall 14 of the present embodiment is located serves as both the longitudinal wall 14 carrier and the outside air inlet passage 2 carrier, simplifying the structure and reducing the manufacturing cost.

Further, in one embodiment, as shown in fig. 1, the longitudinal wall 14 is a side wall of the cavity 12 of the atomizing chamber 1, the aerosol generator 13 is located in a central area surrounded by the side wall, the inner passage openings 22 are formed in the side wall of the cavity 12 of the atomizing chamber 1, the external air inlet passages 2 are multiple, and the inner passage openings 22 are identical in shape and size and are annularly arranged along the longitudinal wall 14.

The housing of the nebulization chamber 1 of the present embodiment serves both as a carrier for the longitudinal wall 14 and as a carrier for the external air inlet channel 2, further simplifying the construction and reducing the manufacturing costs.

Further, in order to better utilize the air flow inside the cavity 12, in one embodiment, as shown in fig. 1, the mist channel 3 is opened at the top of the cavity 12 and extends upward, and the inner channel opening 22 of the external air inlet channel 2 is located lower than the aerosol generator 13.

Further, in one embodiment, as shown in fig. 1 and 6, the longitudinal wall 14 is provided with drainage lines 141 for promoting the surface droplets to gather and slide down, the drainage lines 141 are arranged longitudinally as a whole, and the inner passage ports 22 are disposed on the drainage paths thereof.

The drainage line is of a long strip structure with a ridge shape or a groove shape relative to the surface of the longitudinal wall, and the drainage line promotes liquid drops to gather near the drainage line by utilizing the attraction between solid and liquid molecules so that the enlarged liquid drops slide down into the liquid storage part more easily due to the influence of gravity.

Further, in one embodiment, as shown in fig. 6, the cross section of the drainage wire 141 is groove-shaped.

As shown in fig. 3, another embodiment of the continuous operation type inhalation atomizer kit according to the present invention is provided, wherein the housing of the atomizer chamber 1 extends from the cavity 12 at the top of the cavity 12 toward the lower side thereof a cylindrical structure 15 surrounding the aerosol generator 13 and having an opened lower side, one side of which toward the aerosol generator 13 forms a longitudinal wall 14 surrounding the aerosol generator 13, and the other side thereof forms a lower side-opened nip 121 with the side wall of the cavity 12, as shown in fig. 3, 6, 7 and 9, the cylindrical structure 15 has a sufficient thickness so that the external air inlet passage 2 can be disposed therein in a hollow manner and extends downward from an external passage opening 21 at the top thereof, and the internal passage opening 22 is opened on the longitudinal wall 14.

The longitudinal direction may be a vertical or substantially vertical direction, or may be an incompletely vertical direction having a certain inclination angle.

The sliding path refers to an area which can pass through when the aerosol adheres to the longitudinal wall and gathers into liquid drops to slide down along the longitudinal wall, and the area comprises but is not limited to the surface of the longitudinal wall, the lower edge of the longitudinal wall, a notch formed on the surface of the longitudinal wall or a channel penetrating the longitudinal wall.

Wherein the liquid film formation of the liquid droplets at the inner passage opening is primarily aided by surface tension, the film-forming facilitating structure may assist the liquid droplets in forming a liquid film or mass of liquid on the inner passage opening, which is typically a smaller pore or slit structure of caliber including, but not limited to, small holes, slits or grids, etc. Furthermore, it is advantageous for the liquid film-forming structure to have a sufficient thickness for forming a liquid film or liquid mass, for example by providing the inner passage opening with a length of pores (elongated tubular shape) which, when encountering a droplet, can create a capillary phenomenon, absorb the liquid and form a liquid mass blocking the inner passage opening.

As can be seen from fig. 3, the clamping cavity 121 formed by the cylindrical structure 15 and the outer shell of the cavity 12 surrounds the inner side wall of the cavity 12, the lower part of the cavity 12 is open, the upper part is sealed, and when the atomizing chamber 1 is tilted or inverted due to improper use, the liquid in the liquid storage part 11 can be retained in the clamping cavity 121, so that leakage is avoided. Furthermore, since the longitudinal wall 14 of the present embodiment is arranged around the aerosol generator 13, aerosol may be better contacted to form droplets.

Further, in one embodiment, as shown in fig. 3, the aerosol generator 13 of the continuous operation type inhalation atomizer kit of the present invention is located at the middle region of the liquid storage portion 11 and protrudes toward the upper cavity 12, and is arranged to convert the liquid in the liquid storage portion 11 into aerosol and spray into the cavity 12.

Further, in one embodiment, as shown in fig. 3, the aerosol generator 13 is located in a central area surrounded by the longitudinal wall 14, and the external air inlet channels 2 are multiple, and the internal channel ports 22 are the same in shape and size and are annularly arranged along the longitudinal wall 14.

Further, in order to better utilize the air flow inside the cavity 12, in one embodiment, as shown in fig. 3, the mist channel 3 is opened at the top of the cavity 12 and extends upward, which communicates with the area of the cavity 12 surrounded by the longitudinal wall 14, and the inner channel opening 22 of the external air inlet channel 2 is located lower than the aerosol generator 13.

When the patient inhales, the external ambient air flow breaks through the liquid film at the inner passage opening 22 into the cavity 12, passes through the aerosol generator 13 and moves towards the mist outlet duct 3, so that the aerosol in the cavity 12 can be guided to the patient more fully.

As can be seen from fig. 3, the cylindrical structure 15 and the housing of the cavity 12 form a clamping cavity surrounding the inner side wall of the cavity 12, the lower part of the cavity 12 is open, the upper part is sealed, and when the atomizing chamber 1 is inclined or inverted due to improper use, the liquid in the liquid storage part 11 can be retained in the clamping cavity 121, so as to avoid liquid leakage.

Further, in one embodiment, as shown in fig. 3, 6 and 7, the longitudinal wall 14 is provided with drainage lines 141 for promoting the surface droplets to gather and slide down, the drainage lines 141 are arranged longitudinally as a whole, and the inner passage openings 22 are disposed on the drainage paths thereof.

The drainage path refers to a path through which liquid drops on the inner wall are gathered by the drainage wire and slide down along the drainage wire. The drainage wire comprises, but is not limited to, a body of the drainage wire or the lower side of the drainage wire, a notch formed at a certain position on the drainage wire, a channel penetrating through the drainage wire and the like.

Further, in order to improve the drainage effect, in a specific embodiment, as shown in fig. 6 and 7, the section of the drainage wire 141 is in a groove shape. The inventors found that the groove-shaped drainage wire 141 has a good effect of gathering liquid droplets and guiding the liquid droplets to slide down, and although the cross section thereof is arc-shaped in this embodiment, it may have other shapes such as square, trapezoid, etc.

Further, in one embodiment, as shown in fig. 3, the plurality of inner passage openings 22 of the external air inlet passage 2 are identical in shape and size and are annularly arranged along the longitudinal wall 14.

As shown in fig. 4, another embodiment of the continuous operation type inhalation atomizer kit according to the present invention is that the housing of the atomizer chamber 1 extends from the cavity 12 at the top of the cavity 12 to the lower side thereof to form a cylindrical structure 15 surrounding the aerosol generator 13 and having an open lower side, one side of the cylindrical structure 15 facing the aerosol generator 13 forms a longitudinal wall 14 surrounding the aerosol generator 13, the other side and the side wall of the cavity 12 form a clamping cavity 121 having an open lower side, as shown in fig. 4, 6, 8 and 10, the housing of the cylindrical structure 15 has a sufficient thickness so that the external air inlet channel 2 can be arranged in the housing of the cylindrical structure 15 in a hollow manner, as shown in fig. 4, 8 and 10, the cylindrical structure 15 is provided with a flow guide channel 151 penetrating both sides thereof, the flow guide channel 151 is arranged to guide liquid droplets located at one side of the longitudinal wall 14 into the flow guide channel 151, and the external air inlet channel 2 extends downward from the outer channel port 21 at the top of the cylindrical structure 15 to the flow guide channel 151, and the inner port 22 is opened in the flow guide channel 151.

Wherein the liquid film formation of the liquid droplets at the inner passage opening is primarily aided by surface tension, the film-forming facilitating structure may assist the liquid droplets in forming a liquid film or mass of liquid on the inner passage opening, which is typically a smaller pore or slit structure of caliber including, but not limited to, small holes, slits or grids, etc. Furthermore, the liquid film-forming structure may advantageously have a sufficient thickness for forming a liquid film or liquid mass, for example, by providing the inner passage opening 22 with a length of pores (elongated tubular shape) which, when encountering a droplet, may create a capillary phenomenon, adsorbing the liquid and forming a liquid mass blocking the inner passage opening.

The liquid drop on one side of the longitudinal wall is guided into the flow guide channel by the flow guide channel, so that a liquid film is formed at an inner channel opening formed in the flow guide channel by the liquid drop, and accumulation of liquid clusters in the flow guide channel is reduced, so that excessive internal pressure in a cavity is avoided, and a large amount of liquid is collapsed when the internal gas breaks through the liquid film from the external air entering channel to the external environment. To achieve this, the height of the opening of the flow channel on the side of the clamping chamber is usually lower than the height of the opening of the flow channel on the side of the longitudinal wall.

In addition, the size and the shape of the opening of the diversion channel on one side of the longitudinal wall are not only beneficial to guiding liquid drops into the diversion channel, but also can control the flow of liquid entering the diversion channel and reduce the accumulation of the liquid in the diversion channel. The opening of the diversion channel positioned on one side of the longitudinal wall is square or elliptic.

Further, in one embodiment, as shown in fig. 8, the opening of the diversion channel 151 on one side of the longitudinal wall 14 is square, and has a height of 1.Omm and a width of 5.Omm. When the drop sliding frequency on the longitudinal wall 14 is too high and the flow rate of the liquid entering the diversion channel 151 is saturated, the liquid forms a blocking liquid mass at the opening of the diversion channel 151 at one side of the longitudinal wall 14 and bridges the upper side and the lower side of the opening, so that excessive drops on the longitudinal wall 14 continue to slide downwards along the blocking liquid mass and do not enter the diversion channel 151 any more.

Further, in one embodiment, as shown in fig. 4, the aerosol generator 13 of the continuous operation type inhalation atomizer kit of the present invention is located at the middle region of the liquid storage portion 11 and protrudes toward the upper cavity 12, and is arranged to convert the liquid in the liquid storage portion 11 into aerosol and spray into the cavity 12.

Further, in order to better utilize the air flow inside the cavity 12, in one embodiment, as shown in fig. 4, the mist outlet opening 3 is opened at the top of the cavity 12 and extends upward, and the inner opening 22 of the external air inlet opening 2 is located below the aerosol generator 13. When the patient inhales, the external ambient air flow breaks through the liquid film at the inner passage opening 22 into the cavity 12, passes through the aerosol generator 13 and moves towards the mist outlet duct 3, and can guide the aerosol in the cavity 12 to the patient more smoothly.

As can be seen from fig. 4, the clamping cavity 121 formed by the cylindrical structure 15 and the outer shell of the cavity 12 surrounds the inner side wall of the cavity 12, the lower part of the cavity 12 is open, the upper part is sealed, and when the atomizing chamber 1 is tilted or inverted due to improper use, the liquid in the liquid storage part 11 can be retained in the clamping cavity 121, so that leakage is avoided.

Further, in one embodiment, as shown in fig. 4, the number of the inner passage openings 22 and the diversion passages 151 of the external air inlet passage 2 are plural, and the number, the shape and the size are the same, and the external air inlet passage and the diversion passages are annularly arranged along the longitudinal wall 14.

Further, in one embodiment, as shown in fig. 4 and 8, a drainage line 141 for promoting the surface droplets to gather and slide down is disposed on the longitudinal wall 14, the drainage line 141 is disposed longitudinally as a whole, and an opening of the drainage channel 151 on one side of the longitudinal wall 14 is located on the drainage path thereof.

Further, in order to improve the drainage effect, in a specific embodiment, as shown in fig. 3 and 6, the drainage lines 141 are a plurality of grooves in cross section.

The plurality of drainage lines 141 are annularly arranged along the longitudinal wall 14 and meet the opening of the inner passage opening 22 or the drainage passage 151 at one side of the longitudinal wall 14.

As shown in fig. 11, in a specific embodiment of the mouthpiece 4 suitable for the continuous operation type inhalation atomizer of the present invention, it includes an engagement portion 41 for engaging the mist channel 3, a mouthpiece 42 for a patient, and an exhalation hole 43 therebetween, and when the patient uses the mouthpiece 4 of the inhalation atomizer for respiratory tract and lung treatment, the exhalation air flow of the patient can be discharged from the exhalation hole 43, so as to avoid excessive air blowing into the cavity 12, and the internal pressure suddenly increases to break through the liquid film at the inner channel opening 22, but it is envisioned that the liquid film formation is a dynamic continuous process, even if the patient blows too hard to cause the liquid film to break, the inner channel opening 22 will be rapidly plugged again by the liquid droplet to form a new liquid film.

Further, in a specific embodiment, an elastic valve is disposed between the exhalation hole 43 and the engagement portion 41, and the elastic valve seals the interface member by self-elastic force in a natural state or when the patient exhales, so that the air flow is discharged from the exhalation hole, and is opened to ventilate the tube body when the patient inhales, and the elastic valve can prevent the expiratory air flow from entering the cavity 12 of the nebulization chamber 1, and the structure of the interface member with an elastic valve in this embodiment can refer to the prior art such as CN201061661, and will not be described herein.

It should be understood by those skilled in the art that while the present invention has been described in terms of several embodiments, not every embodiment contains only one independent technical solution. The description is given for clearness of understanding only, and those skilled in the art will understand the description as a whole and will recognize that the technical solutions described in the various embodiments may be combined with one another to understand the scope of the present invention.

The foregoing is illustrative of the present invention and is not to be construed as limiting the scope of the invention. Any equivalent alterations, modifications and combinations thereof will be effected by those skilled in the art without departing from the spirit and principles of this invention, and it is intended to be within the scope of the invention.

Claims

1. A continuous operation inhalation nebulizer kit, comprising:

wherein the top end of the longitudinal wall is connected with other shells of the atomizing chamber, and the part of the shell providing the longitudinal wall has enough thickness so that an external air inlet channel can be arranged in the shell in a hollow mode and extends from the outer channel port, the channel body and the inner channel port from top to bottom;

the device is characterized in that the inner passage opening is arranged to be easy to form a liquid film structure and is arranged on a sliding path of liquid drops on the longitudinal wall, and the inner passage opening is arranged to be a hole or a gap.

2. The inhalation nebulizer kit of claim 1, characterized in that the inner passage opening is lower than the outer passage opening and/or the passage body.

3. The inhalation nebulizer kit of claim 1 wherein the longitudinal wall is a sidewall of the nebulization chamber cavity and the inner port is configured to open onto the sidewall of the nebulization chamber cavity.

4. A kit of parts according to claim 3, wherein said external air inlet channels are plural and are arranged around said side wall.

5. The inhalation atomizer kit according to claim 1, wherein drainage lines for promoting the gathering and sliding of droplets on the surface of the longitudinal walls are arranged on the longitudinal walls, the drainage lines are longitudinally arranged as a whole, and the inner passage openings are arranged on the drainage paths of the drainage lines.

6. The inhalation atomizer kit according to claim 5, wherein said drainage line is fluted or ridged in cross-section.

7. The inhalation nebulizer kit of claim 5, wherein the cross-sectional shape of the drainage wire is selected from the group consisting of arcuate, square, triangular, and trapezoidal.

8. The inhalation atomizer kit according to claim 5, wherein said drainage lines have a width of 0.3-1.5mm and a spacing between the drainage lines of 1.0-6.0mm.

9. The inhalation nebulizer kit of claim 1, characterized in that the continuous operation inhalation nebulizer is a jet nebulizer, the nebulization chamber of which is cylindrical as a whole, the aerosol generator protruding upwards from the middle area of the reservoir into a cavity, being arranged to continuously convert liquid in the reservoir into aerosol and jet into the cavity.

10. The inhalation atomizer kit according to claim 1, wherein the housing of said atomizer chamber extends from the top of the cavity into the cavity at the lower side thereof a tubular structure surrounding the aerosol generator and having an open lower side, one side thereof facing the aerosol generator forming a longitudinal wall surrounding the aerosol generator and the other side thereof forming a lower side open clamping chamber with the side wall of the cavity, said tubular structure having a sufficient thickness to enable an external air inlet passage to be arranged in the housing of said tubular structure in a hollow manner extending downwardly from an external passage opening at the top of the tubular structure, said internal passage opening being provided in the longitudinal wall of the tubular structure.

11. The inhalation nebulizer kit of claim 10, wherein said external air inlet channel is a plurality of and is annularly arranged along said longitudinal wall.

12. The inhalation atomizer kit according to claim 1, wherein the housing of the atomizing chamber extends from the cavity of the lower side of the top of the cavity to a cylindrical structure surrounding the aerosol generator and having an open lower side, one side thereof facing the aerosol generator forms a longitudinal wall surrounding the aerosol generator, the other side forms a sandwiching cavity having an open lower side with the side wall of the cavity, the housing of the cylindrical structure has a sufficient thickness so that an external air inlet passage can be provided in the housing of the cylindrical structure in a hollow manner, the cylindrical structure is provided with a flow guide passage penetrating the side wall thereof, the flow guide passage is arranged to guide liquid droplets located on one side of the longitudinal wall into the flow guide passage, and the external air inlet passage extends downwardly from an external passage opening in the top of the cylindrical structure to the flow guide passage, the internal passage opening being provided in the flow guide passage.

13. The inhalation atomizer kit according to claim 12, wherein said opening of said flow-guiding channel at one side of said longitudinal wall is square or oval with a height of 0.3-3.0mm and a width of 2.0-10.0mm.

14. The inhalation nebulizer kit of claim 1 further comprising an interface member comprising an engagement portion for engaging the nebulizing channel, a mouthpiece for the patient, and an exhalation port therebetween.

15. The inhalation nebulizer kit of claim 14, wherein an elastic valve is further provided between the exhalation port of the mouthpiece and the engagement portion, the elastic valve sealing off the tube body by self-elasticity in a natural state or when the patient exhales, and opening to vent the tube body when the patient inhales.

16. The inhalation nebulizer kit of claim 1 wherein said mist outlet channel opens at the top of the cavity and extends upwardly in communication with the area of the cavity surrounded by said longitudinal wall.

17. The inhalation nebulizer kit of claim 1, wherein said external air inlet channel is a plurality of and is annularly arranged along said longitudinal wall.

18. The inhalation nebulizer kit of claim 12 wherein the lower edge of the opening of the flow-directing channel on the side of the clip chamber is no higher than the lower edge of the opening on the side of the longitudinal surrounding wall, and the upper edge of the opening on the side of the clip chamber is lower than the upper edge of the opening on the side of the longitudinal surrounding wall.

19. The inhalation atomizer kit according to claim 12, wherein said longitudinal wall is provided with drainage lines, said drainage lines being arranged longitudinally as a whole, and said openings of said flow guide channels on one side of said longitudinal wall being arranged in a drainage path.

20. A method of preventing escape of aerosol from an external air inlet channel of an inhalation nebulizer kit of any one of claims 1-19, comprising: an exhalation port is provided on the mouthpiece of the nebulizer so that the patient's expiratory airflow may be expelled through the exhalation port.