CN109700487B

CN109700487B - Conveyor and conveying system

Info

Publication number: CN109700487B
Application number: CN201811640992.9A
Authority: CN
Inventors: 王禹都; 陈贤淼
Original assignee: Lifetech Scientific Shenzhen Co Ltd
Current assignee: Lifetech Scientific Shenzhen Co Ltd
Priority date: 2018-12-29
Filing date: 2018-12-29
Publication date: 2021-09-21
Anticipated expiration: 2038-12-29
Also published as: CN109700487A

Abstract

The invention relates to a conveyor and a conveying system, wherein the conveyor comprises a sleeve, a locking wire and a locking structure, the near end of the sleeve is connected with the locking structure, the locking structure is provided with a through hole along the axial direction, the through hole is communicated with the inner cavity of the sleeve, the locking wire movably penetrates through the through hole of the locking structure and the inner cavity of the sleeve, and the locking structure is in locking connection with the locking wire. The conveyor can convey the plugging device to the part to be plugged.

Description

Conveyor and conveying system

Technical Field

The invention relates to the field of medical instruments, in particular to a conveyor and a conveying system.

Background

Congenital heart disease (congenital heart disease) is a common birth defect, and the incidence rate is 8-12 per mill. Atrial Septal Defects (ASD), Ventricular Septal Defects (VSD), and Patent Ductus Arteriosus (PDA) are common congenital heart Defect diseases.

The interventional occlusion treatment of congenital heart disease is rapidly popularized at home and abroad due to the advantages of slight trauma, safe and rapid operation, definite near-term and medium-term curative effects and the like, and the interventional occlusion treatment becomes a common treatment means for treating congenital heart disease at present, but the technology is also influenced by factors such as the weight of a patient, the pathological anatomy type, the diameter of peripheral blood vessels, the catheter insertion way and the like, and the development of the pediatric cardiology in China is relatively slow, so that the application of interventional treatment is limited to a certain extent. In recent years, new approaches to interventional therapy in surgery or via a surgical incision approach have emerged. The transthoracic minimally invasive plugging technique has the advantages that the cardiac surgeon is familiar with the anatomy, the standardized training of the surgical operation skill is realized, the restriction of age and weight is avoided, the success rate of the operation is higher, meanwhile, the doctor and the patient avoid the radiation, and the technique has obvious technical advantages. The current interventional occlusion treatment for congenital heart disease generally needs to implant an occluder into a part to be occluded (such as ventricular septal defect), and the implantation of the occluder into the part to be occluded needs the conveying function of a conveyor.

Disclosure of Invention

In view of this, it is necessary to provide a conveyor capable of conveying the stopper to the site to be blocked.

A conveyor comprises a sleeve, a locking wire and a locking structure, wherein the locking structure comprises an installation part, a locking seat and a locking part, the installation part is provided with an insertion hole for the insertion of the sleeve, the sleeve is fixedly connected with the installation part in the insertion hole, the locking seat is fixedly connected with the sleeve through the installation part, the locking seat is provided with a through hole along the axial direction of the locking seat, the insertion hole is communicated with the through hole, the through hole is communicated with an inner cavity of the sleeve, the locking wire is movably arranged in the through hole of the locking seat and the inner cavity of the sleeve in a penetrating manner, and the locking part is in locking connection with the locking wire;

the locking wire is detachably connected with the plugging device;

when the locking piece is tightly locked with the locking wire, the plugging device can keep a stable straightening state.

In one embodiment, the locking member comprises a locking claw and a rotating sleeve which can move along the axial direction of the locking claw, the proximal end of the sleeve is fixedly connected with the distal end of the locking seat, the distal end of each locking claw is fixed at the proximal end of the locking seat, and each locking claw is arranged on the periphery of the locking wire; the rotating sleeve comprises a reducing part capable of moving along the axial direction of the locking claw, a reducing hole is formed in the reducing part, the diameter of the reducing hole is gradually reduced along the direction of the far end of the reducing part pointing to the near end of the reducing part, and the reducing part can move along the axial direction of the locking claw.

In one embodiment, the outer wall of the lock base is formed with external threads; the rotary sleeve further comprises an equal-diameter part fixedly connected with the distal end of the variable-diameter part, the equal-diameter part is in a hollow tubular shape, and an internal thread matched with the external thread is formed on the inner wall of the equal-diameter part.

In one embodiment, the locking member further comprises an installation part fixedly connected with the lock seat, the installation part is fixedly connected with the sleeve, the installation part is provided with an insertion hole for inserting the sleeve, the insertion hole is communicated with the through hole, and the lock seat is fixedly connected with the sleeve through the installation part.

In one embodiment, the locking wire comprises a first segment and a second segment fixedly attached to the first segment, the first segment having a larger wire diameter than the second segment, the first segment being closer to the proximal end of the locking wire than the second segment.

In one embodiment, the locking wire further comprises a transition section between the first section and the second section, the proximal end of the transition section being connected to the distal end of the first section, the distal end of the transition section being connected to the proximal end of the second section, the wire diameter of the transition section decreasing from the proximal end to the distal end thereof, the wire diameter at the proximal end of the transition section being equal to the wire diameter of the first section, and the wire diameter at the distal end of the transition section being equal to the wire diameter of the second section.

In one embodiment, the locking wire further comprises a handle structure secured to the proximal end of the first section and a locking head secured to the distal end of the second section, the locking head being formed with external threads.

In one embodiment, the locking member comprises an extrusion part in threaded connection with the lock seat, a side hole communicated with the through hole is formed in the side wall of the lock seat, and threads connected with the extrusion part are formed in the hole wall of the side hole.

In one embodiment, the locking wire is further provided with a first mark and a second mark, the first mark and the second mark are sequentially arranged along the direction that the distal end of the locking wire points to the proximal end, and both the first mark and the second mark can slide along the locking wire to be aligned with the proximal end of the lock base.

In one embodiment, the conveying system comprises the plugging device and the conveyor, wherein the plugging device comprises a plugging unit, a sealing head fixed at the far end of the plugging unit, a bolt head fixed at the near end of the plugging unit and a connecting bolt fixedly connected with the sealing head, the connecting bolt is detachably connected with the locking wire, and the bolt head is detachably connected with the sleeve.

In one embodiment, the plugging unit has a central axis, the central axis passes through the far end and the near end of the plugging device, the plugging device further comprises a marking structure, the marking structure comprises a far-end development mark and at least two first development marks, the far-end development mark is arranged on the plugging head, each first development mark is connected with the plugging unit, each first development mark is located in the same placing plane, the placing plane is perpendicular to the central axis, the far-end development mark is located outside the placing plane, a projection point of each first development mark in a projection plane perpendicular to the placing plane is located on a straight line segment, and in a natural state of the plugging device, a connecting line of the far-end development mark and two end points of the straight line segment is triangular.

In one embodiment, the plugging unit comprises a first subunit, the first subunit comprises a first net disc and a first flow blocking film arranged in the first net disc, a central shaft passes through the geometric center of the first net disc and is perpendicular to the plane of the first net disc, the central shaft passes through the geometric center of the first flow blocking film and is perpendicular to the plane of the first flow blocking film, and each first developing mark is connected with the first net disc, or each first developing mark is connected with the first flow blocking film.

Foretell conveyer passes through the sleeve pipe and the lock silk is connected with the plugging device, the lock silk activity is worn to locate locking structure and sheathed tube, the lock silk can carry out axial motion for locking structure and sleeve pipe, the distal end of lock silk makes the plugging device straighten to the direction motion of keeping away from the sheathed tube distal end, after the plugging device straightens, locking structure makes the lock silk can't carry out axial motion along locking structure and sleeve pipe with the lock silk locking, make the plugging device keep straightening the state, and then make the conveyer carry in can packing the plugging device into the sheath pipe.

Drawings

Fig. 1 is a schematic structural view of a conventional occluder in spaced fit with a chamber.

Fig. 2 is a schematic structural diagram of a conveyor according to an embodiment.

Fig. 3 is a schematic structural view of a locker of the locking structure of the embodiment.

Fig. 4 is a schematic structural view of a swivel sleeve according to an embodiment.

Fig. 5 is a schematic structural view of a lock wire according to an embodiment.

Fig. 6 is a schematic structural diagram of a conveyor according to an embodiment.

Fig. 7 is a schematic structural diagram of a locking structure of an embodiment.

FIG. 8 is a schematic diagram of an embodiment of a conveyor system.

Figure 9 is a schematic view of the configuration of the occluding device and the compartment in a spaced fit in one embodiment.

Fig. 10 is a schematic structural view illustrating the engagement of the occluding device and the sheath in one embodiment.

Figure 11a is a first state diagram of the occluding device in one embodiment.

Figure 11b is a second state diagram of the occluding device in one embodiment.

Figure 11c is a third state diagram of the occluding device in an embodiment.

Figure 11d is a fourth state diagram of the occluding device in an embodiment.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, but rather should be construed as broadly as the present invention is capable of modification in various respects, all without departing from the spirit and scope of the present invention.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

To more clearly describe the structure of the present invention, the terms "distal" and "proximal" are used as terms of orientation that are conventional in the medical device art, wherein "distal" refers to the end of the device that is distal from the operator during the procedure, and "proximal" refers to the end of the device that is proximal to the operator during the procedure.

Congenital heart disease (congenital heart disease) is a common birth defect, generally including atrial septal defect, ventricular septal defect, and patent ductus arteriosus. The present invention is illustrated by way of example and not by way of limitation, in the treatment of ventricular septal defects. As shown in figure 1, treatment of a ventricular septal defect can be accomplished by occluding device 100 of the defect in ventricular septum 200. The occluder 100 comprises a left disc 111, a right disc 112 connected with the left disc 111, a head 113 fixed at the far end of the left disc 111, a bolt head 114 fixed at the near end of the right disc 112, and a connecting bolt 115 integrally connected with the head 113, wherein the bolt head 114 is provided with a connecting hole (not shown) for the connecting bolt 115 to insert and fixedly connect with the connecting bolt 115, the outer side wall of the bolt head 114 is provided with an external thread (not shown), the near end of the connecting bolt 115 is provided with a lock hole (not shown), and the wall of the lock hole is provided with an internal thread (not shown). The occluding device 100 can occlude a defect in the ventricular septum 200 when in its natural state.

It should be noted that when the connection bolt 115 is inserted into the connection hole of the bolt head 114 and the connection bolt 115 is tightly fixed with the bolt head 114, the occluder 100 is in a natural state. The left disc 111 and the right disc 112 each have their own shape when the occluding device 100 is in a natural state. In any case, as long as the shape of the left disc 111 is deformed to be the same as the shape when it is in the natural state, the left disc 111 can be considered to be in the natural state. In any case, as long as the shape of the right disk 112 is deformed to be the same as the shape in the natural state, the right disk can be regarded as being in the natural state.

Example one

As shown in FIG. 2, according to the first embodiment, a delivery device 300 comprises a cannula 311, a locking wire 321 and a locking structure 330, wherein the locking structure comprises a mounting portion 336, a locking seat 333 and a locking member 331, the mounting portion 336 is provided with an insertion hole 337 into which the cannula 311 is inserted, the cannula 311 is fixedly connected with the mounting portion 336 in the insertion hole 337, and the locking seat 333 is fixedly connected with the cannula 311 through the mounting portion 336. As shown in fig. 3, the lock holder 333 is provided with a through hole 335 along its axial direction. The insertion hole 337 is communicated with the through hole 335, the through hole 335 is communicated with the inner cavity of the cannula 311, the locking wire 321 is movably arranged in the through hole 335 of the locking seat 333 and the inner cavity of the cannula 311, and the locking member 331 is in lockable connection with the locking wire 321.

The delivery device 300 in this embodiment is connected to the occluding device 100, and the occluding device 100 can be loaded into a sheath to be delivered to the defect of the ventricular septum 200, so that the occluding device 100 is unfolded and molded into a natural state at the defect of the ventricular septum 200 to occlude the ventricular septum defect.

Prior to surgery, delivery device 300 is attached to occluding device 100 with the distal end of locking wire 321 attached to the proximal end of connecting plug 115 and the distal end of cannula 311 attached to head 114. The locking wire 321 is movably arranged in the through hole 335 of the lock holder 333 and the inner cavity of the cannula 311, the locking wire 321 can move axially along the lock holder 333 and the cannula 311, and can drive the connecting bolt 115 to be inserted into the lock hole to clamp and fix the connecting bolt 115 and the bolt head 114, so that the occluder 100 is formed into a natural state, and the occluder 100 can occlude the ventricular septal defect. The distal end of the locking wire 321 moves in a direction away from the distal end of the sleeve 311, which can drive the connecting bolt 115 to exit the locking hole, so that the sealing head 113 and the bolt head 114 move away from each other until the left disc 111 and the right disc 112 straighten (i.e. the straightened state of the occluder 100), so that the transporter 300 can transport the occluder 100 after the occluder 100 is loaded into a sheath.

The locking member 331 is lockably connected to the locking wire 321, i.e. the locking member 331 can be lockingly engaged or disengageably engaged with the locking wire 321. When the locking member 331 is unlocked and engaged with the locking wire 321, the locking wire 321 can axially move along the through hole 335 of the locking seat 333 and drive the connecting bolt 115 to move, so that the occluder 100 can be freely switched from the straightened state to the natural state. When the locking member 331 is locked and matched with the locking wire 321, the locking wire 321 cannot move axially along the locking seat 333, so that the occluding device 100 maintains a stable structural shape (e.g., a straight state or a natural state).

During operation, the delivery device 300 is locked and matched with the locking wire 321 through the locking piece 331, so that the occluding device 100 is kept in a straightened state, and the delivery device 300 can complete delivery of the occluding device 100. In the conveying process, the conveyor 300 keeps the occluder 100 in a straight state, so that the radial sizes of the left disc 111 and the right disc 112 of the occluder 100 can be reduced, the friction force between the occluder 100 and a sheath can be further reduced, the resistance of the occluder 100 during release can be reduced, and the friction damage of the inner wall of the sheath to the occluder 100 can be further reduced. When the delivery device 300 delivers the occluder 100 to a desired position and releases the occluder 100, the locking member 331 is unlocked from the locking wire 321, the locking wire 321 moves axially along the locking seat 333 and the sleeve 311 and drives the connecting bolt 115 to be inserted into the connecting hole, so that the occluder 100 is kept in a natural state. The conveyor of the embodiment has the advantages of simple structure, convenient manufacture, higher reliability and low misoperation probability, and can be used for two treatment means of transthoracic minimally invasive and percutaneous intervention.

As shown in fig. 2, the outer surface of the sleeve 311 is provided with an anti-slip pattern. When the sleeve 311 is held, the sleeve 311 can be prevented from slipping.

The material of the sleeve 311 may be, but is not limited to, metal and polymer material, the sleeve 311 may be a hollow tube, a spring tube, and the like, and the sleeve 311 is preferably a stainless steel spring tube with a constant thickness. Specifically, the sleeve 311 is formed by winding 9 stainless steel wires having a diameter of 0.37 mm, and the sleeve 311 is elastically deformed to conform to a curved blood vessel. The outer diameter of the sleeve 311 is 1.6 mm, and the length is 200-1500 mm.

Delivery device 300 further includes a locking sleeve 312 secured to the distal end of cannula 311, locking sleeve 312 being tubular in configuration and the inner wall of locking sleeve 312 being formed with connecting threads. The connecting threads of the sleeve 312 mate with the external threads of the bolt head 114 to removably connect the sleeve 312 to the bolt head 114.

Specifically, the material of the lock sleeve 312 may be, but is not limited to, metal and polymer material, and the material of the lock sleeve 312 is preferably made of steel material.

The material of the locking structure 330 may be, but is not limited to, metal and polymer material. The material of the locking structure 330 is preferably stainless steel. The locker 331 includes a locking claw 332 and a rotating sleeve 351 axially movable along the locking claw 332.

As shown in fig. 3, retaining member 331 includes a plurality of retaining fingers 332. The distal end of each locking claw 332 is fixed to the proximal end of the locking seat 333, each locking claw 332 is fixedly connected with the sleeve 311 through the locking seat 333, and each locking claw 332 is arranged on the periphery of the locking wire 321.

The through hole 335 is opened on the lock seat 333, the through hole 335 is opened along the axial direction of the lock seat 333, and the through hole 335 is communicated with the inner cavity of the cannula 311. Locking wire 321 may pass through throughbore 335 of locking receptacle 333 into the lumen of cannula 311. The outer wall of the key holder 333 is formed with an external thread 334 extending in the axial direction thereof, and the external thread 334 of the key holder 333 has an outer diameter of 3 mm.

A plurality of locking claws 332 are arranged circumferentially, and specifically, the number of the locking claws 332 is 4. The axial length of the locking claws 332 is 8 mm.

As shown in fig. 4, the sleeve 351 includes a diameter-variable portion 352 capable of moving along the axial direction of the locking claw 332, the diameter-variable portion 352 is opened with a diameter-variable hole 353, and the diameter of the diameter-variable hole 353 gradually decreases from the distal end of the diameter-variable portion 352 to the proximal end of the diameter-variable portion 352. The diameter-variable portion 352 can move axially along the locking claws 332 to the hole wall of the diameter-variable hole 353 to radially compress each locking claw 332 to clamp the locking wire 321.

In this embodiment, the diameter-variable portion 352 moves axially along the locking claw 332, the proximal end of the diameter-variable portion 352 is gradually close to the distal end of the locking claw 332, the hole wall of the diameter-variable hole 353 of the diameter-variable portion 352 is in contact with the locking claw 332, the hole diameter of the diameter-variable hole 353 is gradually reduced along the direction from the distal end of the diameter-variable portion 352 to the proximal end of the diameter-variable portion 352, in the process that the minimum hole diameter of the diameter-variable hole 353 of the diameter-variable portion 352 is gradually close to the distal end of the locking claw 332, the hole wall of the diameter-variable hole 353 of the diameter-variable portion 352 is in compression fit with the locking claw 332 so that the locking claw 332 elastically deforms along the radial direction, each locking claw 332 is disposed on the periphery of the locking wire 321, and therefore the diameter-variable portion 352 can compress the locking claw 332 to clamp the locking wire 321, so that the locking member 331 can be in locking fit with the locking wire 321.

In this embodiment, the diameter of the diameter-variable hole 353 gradually decreases along the direction from the distal end of the diameter-variable portion 352 to the proximal end of the diameter-variable portion 352, the diameter-variable portion 352 axially moves along the locking claw 332 and is away from the proximal end of the locking claw 332, the locking claw 332 gradually returns to the self-straightening state, and each locking claw 332 gradually releases the locking wire 321, so that the locking member 331 can be in unlocking fit with the locking wire 321.

The minimum aperture of the diameter-variable hole 353 is larger than the wire diameter of the locking wire 321, so that the locking wire 321 can be ensured to move axially along the locking member 331 when the locking member 331 is in unlocking fit with the locking wire 321. Specifically, the minimum aperture of the reducing holes 353 is 1.2 mm, and the maximum aperture of the reducing holes 353 is 3.0 mm.

As shown in fig. 4, the rotating sleeve 351 further includes an equal diameter portion 354 fixedly connected to a distal end of the variable diameter portion 352, the equal diameter portion 354 is hollow and tubular, an inner wall of the equal diameter portion 354 is formed with an inner thread 355 engaged with the outer thread 334, and the equal diameter portion 354 moves along the outer thread 334 to drive the variable diameter portion 352 to move axially along the locking claw 332.

In this embodiment, the internal thread 355 of the constant diameter portion 354 is engaged with the external thread 334 of the lock holder 333, the constant diameter portion 354 moves in the axial direction of the lock holder 333 while rotating relative to the lock holder 333, and the constant diameter portion 354 can drive the variable diameter portion 352 to move in the axial direction of the lock holder 333. The locking seat 333 is fixedly connected with each locking claw 332, and the constant diameter portion 354 drives the variable diameter portion 352 to move axially along the locking seat 333, namely, the constant diameter portion 354 drives the variable diameter portion 352 to move axially along the locking claw 332, so that the locking member 331 is locked with or unlocked from the locking wire 321. The conveyor 300 has a simple structure, is convenient to operate, and has high reliability in use.

As shown in FIG. 5, locking wire 321 includes a first segment 322 and a second segment 324 fixedly attached to first segment 322, the wire diameter of first segment 322 being greater than the wire diameter of second segment 324, first segment 322 being closer to the proximal end of locking wire 321 than second segment 324. So that first section 322 has higher structural strength and larger wire diameter relative to second section 324, and the locking fit of locking wire 321 and retaining member 331 is more stable when the locking wire is in locking fit with the retaining member. The second section 324 is more flexible relative to the first section 322, and the second section 324 can conform to a curved shape of a vessel during delivery.

Specifically, the locking wire 321 may be, but not limited to, a metal and a polymer material, and the locking wire 321 may be a single wire, a plurality of wires, a hollow tube, or the like. Locking wire 321 is preferably a single nickel titanium wire having a wire diameter of 0.65 mm for first section 322 and 0.4 mm for second section 324.

The locking wire 321 further includes a transition 325 between the first section 322 and the second section 324, the transition 325 having a proximal end connected to the distal end of the first section 322, a distal end connected to the proximal end of the second section 324, the transition 325 having a wire diameter that decreases from its proximal end to its distal end, the proximal end of the transition 325 having a wire diameter that is equal to the wire diameter of the first section 322, and the distal end of the transition 325 having a wire diameter that is equal to the wire diameter of the second section 324.

In this embodiment, when the distal end of the transition section 325 is connected to the proximal end of the lock holder 333, the wire diameter of the transition section 325 gradually decreases from the proximal end to the distal end, so as to prevent the interference between the end surface of the distal end of the first section 322 and the end surface of the proximal end of the lock holder 333, which may cause the occlusion device 100 not to be straightened.

As shown in fig. 5, the locking wire 321 further includes a handle structure 323 fixed to the proximal end of the first section 322 and a locking head 326 fixed to the distal end of the second section 324, the locking head 326 is formed with an external thread, the external thread of the locking head 326 has an external diameter of 0.6 mm, and the external thread of the locking head 326 has an axial extension length of 1.5 mm. The external thread of the locking head 326 is connected with the internal thread of the connecting bolt 115.

Before operation, the delivery device 300 is connected with the occluding device 100 through the locking wire 321 and the locking sleeve 312. During operation, the locking wire 321 can drive the sealing head 113 to move away from or close to the plug head 114 through the connecting bolt 115, thereby changing the shape of the occluding device 100. For example, the locking wire 321 can drive the sealing head 113 to approach the plug head 114 through the connecting bolt 115, so that the occluder 100 is in a natural state, and is tightly clamped with the plug head 114 through the connecting bolt 115, so that the occluder 100 is kept in the natural state, and the occluder 100 can continuously occlude the ventricular septum 200. After the implantation of the occluding device 100 is completed, the locking sleeve 312 and the plug head 114 are rotated to be separated, and the locking wire 321 and the connecting plug 115 are rotated to be separated, so that the conveyer 300 is separated from the occluding device 100, and the occluding device 100 is kept at the defect of the ventricular septum 200 while the conveyer 300 is withdrawn.

The pull tab structure 323 can facilitate application of a force to the locking wire 321 to drive the locking wire 321 to move axially and rotate. Specifically, the locking wire 321 can change the shape of the occluding device 100 when moving axially, and the locking wire 321 can unlock the connecting bolt 115 when the locking wire 321 rotates.

As shown in FIG. 5, the locking wire 321 is further provided with a first mark 327 and a second mark 328, the first mark 327 and the second mark 328 are sequentially arranged along the proximal direction of the distal end of the locking wire 321, and both the first mark 327 and the second mark 328 can slide along the locking wire 321 to be aligned with the proximal end of the lock base 333. Wherein, when the first mark 327 slides to align with the proximal end of the lock seat 333 along with the lock wire 321, the connecting bolt 115 is inserted into the connecting hole of the bolt head 114, and the occluding device 100 is in a natural state. When the second marker 328 is slid along the locking wire 321 into alignment with the proximal end of the lock holder 333, the occluding device 100 is in a straightened state. The first 327 and second 328 markings are each annular in shape, and the first 327 and second 328 markings are always visible to an operator during 360 degrees of conveyor rotation.

Example two

One difference between the second embodiment and the first embodiment is that, as shown in FIG. 6, the locker 430 of the delivery device 400 of the second embodiment comprises a locking holder 431 fixed to the proximal end of the casing 411 and a pressing member 432 threadedly coupled to the locking holder 431, as shown in FIG. 7, a through hole 435 is formed in the locking holder 431, a side hole (not shown) penetrating the through hole 435 is formed in a side wall of the locking holder 431, a thread coupled to the pressing member 432 is formed in a wall of the side hole, and the pressing member 432 is movable along the side hole to be press-fitted to or separated from the locking wire 421 disposed in the through hole 435.

In this embodiment, the pressing member 432 is screw-coupled to the locking holder 431, and the pressing member 432 is movable along the side hole to be press-fitted into or separated from the locking wire 421 located in the through hole 435, thereby achieving the lockable coupling of the locker 430 to the locking wire 421. The conveyor 400 in the embodiment rotates relative to the lock seat 431 through the extrusion part 432, and simultaneously, the extrusion part 432 moves to extrude the lock wire 421 or is separated from the lock wire 421 along the axial direction, so that the conveyor 400 is simple in structure, convenient to manufacture, high in reliability and low in misoperation probability, and can be used for two treatment means of transthoracic minimally invasive and percutaneous intervention.

Extrusion 432 is injection molded from Acrylonitrile Butadiene Styrene (ABS) plastic and stainless steel. The pressing member 432 is rotated in a first direction to lock the locking wire 421, and the pressing member 432 is rotated in a second direction opposite to the first direction, and the pressing member 432 is separated from the locking wire 421.

The opening direction of the side hole is perpendicular to the opening direction of the through hole 435. When the pressing member 432 moves along the side hole to be in pressing fit with the locking wire 421, the contact area between the end of the pressing member 432 and the locking wire 421 can be increased, and the locking force of the locking member 430 on the locking wire 421 can be increased. Meanwhile, the pressure of the extrusion part 432 on the lock wire 421 can be reduced, and the service life of the lock wire 421 is further prolonged.

The second embodiment is different from the first embodiment in that the delivery device 400 of the second embodiment does not include the handle structure 323 of the first embodiment, and the delivery device 400 of the second embodiment includes a handle 423 connected to the proximal end of the locking wire 421, and the handle 423 is connected to the proximal end of the locking wire 421 through an ABS injection molding. The outer wall of the handle 423 is formed with a mesh. The locking wire 421 can be forced by the handle 423 to move and rotate the locking wire 421 along the through hole 435 in the axial direction. The texture on the handle 423 prevents slippage when a force is applied to the handle 423.

EXAMPLE III

According to the third embodiment, a conveying system 700 is provided, which comprises the plugging device 500 and the conveyor 300, as shown in fig. 8, the plugging device 500 comprises a plugging unit 50, a sealing head 541 fixed at the distal end of the plugging unit 50, a bolt head 551 fixed at the proximal end of the plugging unit 50, a connecting bolt 561 fixedly connected with the sealing head 541, and a marking structure 60 connected with the plugging unit 50.

The free end of the connection bolt 561 is provided with a threaded hole matched with the lock head 326, and the connection bolt 561 is connected with the lock head 326 through the threaded hole. The outer wall of the bolt head 551 is provided with an external thread matched with the internal thread of the lock sleeve 312, and the bolt head 551 is connected with the lock sleeve 312 through the external thread. So that the stopper 500 is detachably mounted on the conveyor 300.

As shown in fig. 8, the plugging unit 50 has a central axis a-a, the central axis a-a passes through the distal end and the proximal end of the plugging device 500, the marking structure 60 includes a distal development mark 611 and at least two first development marks 612, the distal development mark 611 is disposed on the sealing head 541, each first development mark 612 is connected to the plugging unit 50, each first development mark 612 is located in the same placing plane, the placing plane is perpendicular to the central axis a-a, the distal development mark 611 is located outside the placing plane, a projection point of each first development mark 612 in a projection plane perpendicular to the placing plane is located on a straight line segment, and a connection line between the distal development mark 611 and two end points of the straight line segment is triangular in a natural state of the plugging device 500. During release of the occluding device 500, the marker structure 60 may be developed under DSA to guide the release of the occluding device 500.

The occluding device 500 of the present embodiment is used to occlude a defect in the ventricular septum 200 as shown in figure 9. Referring also to fig. 10, before use, the occluder 500 is connected to the conveyor 300, and then the occluder 500 is loaded into the sheath 400 along with the conveyor 300, the sheath 400 having an inner diameter of 2-5 mm. The specific connection between the stopper 500 and the conveyor 300 is described above and will not be described further. When the occluder 500 is implanted, it is necessary to perform a surgical operation under guidance of an X-ray imaging device such as DSA (Digital Subtraction Angiography), so that the occluder 500 is delivered to a relevant lesion site along the sheath 400, and then the sleeve 311 applies a force to the sheath 311 to drive the occluder 500 to move axially along the sheath 400, so as to release the occluder 500 from the sheath 400 to the ventricular septum 200 to occlude the defect of the ventricular septum 200. Specifically, after the sheath 400 loaded with the occluding device 500 passes through the interventricular septum 200, the force is applied to the occluding device 500 to move the occluding unit 50 out of the sheath 400, and then the locking wire 321 is pulled to expand the occluding unit 50, so as to occlude the defect.

Specifically, as shown in fig. 11a, the occluder 500 is applied with a force to be deployed in the left atrium (only the occluder 500 is deployed in the left atrium here, but not limited thereto), parameters such as the probe angle of the DSA are adjusted, so that the projection point of each first visualization mark 612 in a projection plane perpendicular to the placement plane in the DSA detected image is located on a straight line segment, and the connection line between the distal visualization mark 611 and two end points of the straight line segment is triangular, at this time, the operator can apply a force to the occluder 500 to reciprocate the occluder 500, and by observing whether the triangle is deformed during the reciprocating motion, if the triangle is not deformed during the reciprocating motion, it can be determined that the occluding unit 50 is not attached to the ventricular septum 200.

As shown in FIG. 11b, the force is continuously applied to the occluding unit 50, so that the occluding unit 50 moves to the proximal end until each of the first visualization marks 612 is attached to the ventricular septum 200, and during the process, the operator can be guided to perform the operation by observing the geometric shape of the triangle, thereby assisting the operator to understand the position relationship between the occluding unit 50 and the ventricular septum 200 for the subsequent operation of the occluding device 500. Specifically, after each first development mark 612 is attached to the chamber partition 200, the movement of each first development mark 612 is limited, and the distal development mark 611 can move freely, at this time, the distal development mark 611 continues to approach the chamber partition 200 and the first development mark 612, and the triangle is deformed, and at this time, it can be determined that the blocking unit 50 is attached to the chamber partition 200.

As shown in fig. 11c, after the plugging unit 50 is attached to the ventricular septum 200, if the plugging device 500 is continuously pulled to the proximal end, the distal end development mark 611 continues to approach the ventricular septum 200, and if the projection of the distal end development mark 611 is collinear with the straight line segment, the distal end development mark 611 continues to move to the ventricular septum 200 by further applying a force to the plugging device 500. As shown in fig. 11d, the distal end visualization mark 611 may cross the defect position of the ventricular septum 200, causing the occluder 500 to fall off, so that when the projection of the distal end visualization mark 611 is collinear with the straight line segment, the effect of warning and prompting can be provided for the operator, and the distal end visualization mark 611 is prevented from crossing the defect position of the ventricular septum 200, thereby preventing the occluder 500 from falling off, therefore, the occluder 500 in this embodiment can determine the accurate position and the release state thereof under DSA, and the success rate of the surgery is improved.

Further, as shown in fig. 8, the plugging unit 50 includes a first subunit 51, the first subunit 51 includes a first mesh tray 511 and a first current blocking film 512 disposed in the first mesh tray 511, a central axis a-a passes through a geometric center of the first mesh tray 511, the central axis a-a is perpendicular to a plane where the first mesh tray 511 is located, the central axis a-a passes through the geometric center of the first current blocking film 512, the central axis a-a is perpendicular to the plane where the first current blocking film 512 is located, and each of the first developing marks 612 is connected to the first mesh tray 511. Alternatively, in other embodiments, each first development mark 612 is connected to the first flow blocking film 512.

In this embodiment, the central axis a-a passes through the geometric center of the first screen tray 511, and the central axis a-a is perpendicular to the plane of the first screen tray 511, so that the plane of the first screen tray 511 is perpendicular to the projection plane, each of the first development marks 612 is connected to the first screen tray 511, the projections of the first development marks 612 in the projection plane can be located on the same straight line segment, and the connection line between the projection of the far-end development mark 611 and the two ends of the straight line segment is triangular. Similarly, the central axis a-a passes through the geometric center of the first current blocking film 512, and the central axis a-a is perpendicular to the plane of the first current blocking film 512, so that the plane of the first current blocking film 512 is perpendicular to the projection plane, each first development mark 612 is connected to the first current blocking film 512, the projection of each first development mark 612 in the projection plane is located on the same straight line segment, and further, the projection of the far-end development mark 611 and the connection line of the two ends of the straight line segment form a triangle.

As shown in fig. 11a, in the operation, an acting force is applied to the occluder 500 to expand the first subunit 51 in the left atrium, and parameters such as the probe angle of the DSA are adjusted to make the projection point of each first visualization mark 612 in the projection plane in the image detected by the DSA located on a straight line segment, and make the connection line between the distal visualization mark 611 and the two end points of the straight line segment form a triangle, so that the operator can apply an acting force to the occluder 500 to reciprocate the occluder 300, and by observing whether the triangle deforms during the reciprocating motion, if the triangle does not deform during the reciprocating motion, it can be determined that the occluding unit 50 is not attached to the room interval 200.

As shown in FIG. 11b, the force is continuously applied to the occluding unit 50, so that the occluding unit 50 moves proximally until the first mesh disk 511 or the first flow-blocking membrane 512 is attached to the ventricular septum 200, and during the process, the geometrical configuration of the triangle is observed to assist the surgeon to understand the position relationship between the first mesh disk 511 and the ventricular septum 200, so as to operate the subsequent release of the occluding device 500. Specifically, when the first screen disc 511 or the first flow blocking film 512 is attached to the chamber partition 200, the movement of each first development mark 612 is limited, and the distal development mark 611 can move freely, at this time, the distal development mark 611 continues to approach the chamber partition 200 and the first development mark 612, and the triangle is deformed, and at this time, it can be determined that the first subunit 51 is attached to the chamber partition 200.

As shown in fig. 11c, after the first subunit 51 is attached to the ventricular septum 200, if the stopper 500 is further pulled proximally, the distal end development mark 611 continues to approach the ventricular septum 200, and when the projection of the distal end development mark 611 is collinear with the straight line segment, the distal end development mark 611 continues to move closer to the ventricular septum 200 if the force is further applied to the stopper 500.

As shown in fig. 11d, the distal end visualization mark 611 may cross the defect position of the ventricular septum 200, causing the occluder 500 to fall off, so that when the projection of the distal end visualization mark 611 is collinear with the straight line segment, the projection of the distal end visualization mark 611 can provide an early warning and prompt for the operator, thereby preventing the distal end visualization mark 611 from crossing the defect position of the ventricular septum 200, further preventing the occluder 500 from falling off, and improving the success rate of the operation.

In this embodiment, in use of the occluding device 500, the first mesh 511 and the first flow-blocking membrane 512 are delivered to the defect of the ventricular septum 200 for occluding the defect of the ventricular septum 200. The first mesh disk 511 is made of a material with elastic memory, when the first mesh disk 511 is transported to a desired position and moves out of the sheath 400, the first mesh disk 511 can expand and recover to a natural state under the action of its own elastic force, and the first mesh disk 511 can drive the first flow blocking membrane 512 to expand when recovering to the natural state, so that the first mesh disk 511 and the first flow blocking membrane 512 block the defect of the ventricular septum 200.

As shown in fig. 8, the plugging unit 50 further includes a second subunit 52 connected to the first subunit 51, the second subunit 52 includes a second mesh plate 521 and a second flow resistance film 522 disposed in the second mesh plate 521, the central axis a-a passes through the geometric center of the second mesh plate 521 and is perpendicular to the plane of the second mesh plate 521, the central axis a-a passes through the geometric center of the second flow resistance film 522 and is perpendicular to the plane of the second flow resistance film 522, the marker structure 60 further includes at least two second development marks 613, each second development mark 613 is connected to the second mesh plate 521, or each second development mark 613 is connected to the second flow resistance film 522.

In this embodiment, the central axis a-a passes through the geometric center of the second screen disc 521, and the central axis a-a is perpendicular to the plane of the second screen disc 521, so that the plane of the second screen disc 521 is perpendicular to the projection plane, and each second development mark 613 is connected to the second screen disc 521, so that the projections of each second development mark 613 in the projection plane are located on the same straight line segment. Similarly, the central axis a-a passes through the geometric center of the second current blocking film 522, and the central axis a-a is perpendicular to the plane of the second current blocking film 522, so that the plane of the second current blocking film 522 is perpendicular to the projection plane, and each of the second development marks 613 is connected to the second current blocking film 522, so that the projections of each of the second development marks 613 in the projection plane are located on the same straight line segment.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A conveyor can be used for conveying a plugging device and is characterized by comprising a sleeve, a locking wire and a locking structure, wherein the locking structure comprises an installation part, a locking seat and a locking part, the installation part is provided with a jack for the insertion of the sleeve, the sleeve is fixedly connected with the installation part in the jack, the locking seat is fixedly connected with the sleeve through the installation part, the locking seat is provided with a through hole along the axial direction of the locking seat, the jack is communicated with the through hole, the through hole is communicated with the inner cavity of the sleeve, the locking wire is movably arranged in the through hole of the locking seat and the inner cavity of the sleeve in a penetrating manner, and the locking part is connected with the locking wire in a locking manner;

the locking wire is detachably connected with the plugging device;

when the locking piece is locked and matched with the locking wire, the plugging device can be kept in a stable straightened state.

2. The conveyor according to claim 1, wherein said locking member includes a locking claw and a rotating sleeve axially movable along said locking claw, a proximal end of said sleeve is fixedly connected to a distal end of said locking seat, a distal end of each of said locking claws is fixed to a proximal end of said locking seat, and each of said locking claws is disposed at an outer periphery of said locking wire; the rotary sleeve comprises a diameter-variable part capable of moving along the axial direction of the locking claw, a diameter-variable hole is formed in the diameter-variable part, the diameter of the diameter-variable hole is gradually reduced along the direction of the far end of the diameter-variable part to the near end direction of the diameter-variable part, and the diameter-variable part can move along the axial direction of the locking claw.

3. The conveyor apparatus of claim 2, wherein an outer wall of said lock housing is formed with an external thread; the rotary sleeve further comprises an equal-diameter part fixedly connected with the far end of the variable-diameter part, the equal-diameter part is in a hollow tubular shape, and an internal thread matched with the external thread is formed on the inner wall of the equal-diameter part.

4. The conveyor apparatus of claim 1 wherein said lockwire includes a first section and a second section fixedly attached to said first section, said first section having a wire diameter greater than a wire diameter of said second section, said first section being closer to a proximal end of said lockwire than said second section.

5. The conveyor apparatus of claim 4 wherein said lock wire further comprises a transition section between said first section and said second section, said transition section having a proximal end connected to said first section distal end and a distal end connected to said second section proximal end, said transition section having a wire diameter that decreases from said proximal end to said distal end, said transition section proximal end having a wire diameter equal to said first section wire diameter and said transition section distal end having a wire diameter equal to said second section wire diameter.

6. The conveyor apparatus of claim 4 or 5 wherein said locking wire further comprises a pull structure secured to a proximal end of said first section and a locking head secured to a distal end of said second section, said locking head being formed with external threads.

7. The conveyor according to claim 1, characterized in that said locking member comprises an extrusion member screwed to said locking seat, a side hole penetrating said through hole is provided on the side wall of said locking seat, and a screw thread screwed to said extrusion member is provided on the wall of said side hole.

8. The conveyor apparatus of claim 2 or 7 wherein said locking wire further has first and second indicia disposed thereon, said first and second indicia being sequentially aligned in a proximal direction of the distal end of said locking wire, said first and second indicia being slidable with said locking wire into alignment with the proximal end of said lock housing.

9. A conveying system comprising an occluder and a conveyor according to any one of claims 1 to 8, said occluder comprising an occluding unit, a closure head secured to a distal end of said occluding unit, a plug secured to a proximal end of said occluding unit and a connecting bolt fixedly connected to said closure head, said connecting bolt being detachably connected to said locking wire and said plug being detachably connected to said sleeve.

10. The delivery system of claim 9, wherein the occlusion unit has a central axis, the central axis passes through the distal and proximal ends of the occluding device, the occluding device further comprises a marker structure, the marking structure comprises a far-end developing mark and at least two first developing marks, the far-end developing mark is arranged on the sealing head, each first developing mark is connected with the sealing unit, each first developing mark is positioned in the same placing plane, the placing plane is vertical to the central axis, the far-end developing marks are positioned outside the placing plane, the projection point of each first developing mark in a projection plane vertical to the placing plane is positioned on a straight line segment, in a natural state of the occluder, a connecting line of the far-end development mark and two end points of the straight line segment is triangular.

11. The conveying system according to claim 10, wherein the plugging unit comprises a first subunit, the first subunit comprises a first net disc and a first flow blocking film arranged in the first net disc, the central shaft passes through a geometric center of the first net disc and is perpendicular to a plane of the first net disc, the central shaft passes through a geometric center of the first flow blocking film and is perpendicular to a plane of the first flow blocking film, and each of the first development marks is connected with the first net disc, or each of the first development marks is connected with the first flow blocking film.