CN109700475A - A kind of coronary artery bypass grafting determination method for parameter, device, electronic equipment and computer storage medium - Google Patents
A kind of coronary artery bypass grafting determination method for parameter, device, electronic equipment and computer storage medium Download PDFInfo
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- CN109700475A CN109700475A CN201811614134.7A CN201811614134A CN109700475A CN 109700475 A CN109700475 A CN 109700475A CN 201811614134 A CN201811614134 A CN 201811614134A CN 109700475 A CN109700475 A CN 109700475A
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Abstract
The embodiment of the invention discloses a kind of coronary artery bypass grafting determination method for parameter, it include: the data according to coronary artery CTA, obtain the coronary artery with stenotic lesion, and determine outlet to be measured, coronary artery with stenotic lesion is repaired, obtain the coronary artery of no stenotic lesion, according to the impedance of outlet to be measured, determine the blood flow total value of outlet to be measured in the coronary artery of no stenotic lesion, according to the scheme of CABG, coronary artery with stenotic lesion is bridged, coronary artery after obtaining CABG, according to the impedance of outlet to be measured, the blood flow total value of outlet to be measured in coronary artery after determining CABG, according to the blood flow total value of outlet to be measured in the blood flow total value of outlet to be measured in the coronary artery after CABG and the coronary artery without stenotic lesion, determine coronary artery bypass grafting parameter.The embodiment of the present invention further simultaneously discloses determining device, electronic equipment and the computer storage medium of a kind of coronary artery bypass grafting parameter.
Description
Technical field
The present invention relates to the coronary arterys of coronary artery bypass grafting (CABG, Coronary Artery Bypass Graft) to take
Bridge parameter determines that technology more particularly to a kind of coronary artery bypass grafting determination method for parameter, device, electronic equipment and computer storage are situated between
Matter.
Background technique
Coronary artery (referred to as coronary artery) connects aorta ascendens and cardiac muscle, is myocardial blood supply, cardiac muscle control cardiac cycle
Ground diastole and contraction can cause deficiency myocardial blood supply to lead to myocardial infarction if coronary artery generation is narrow, and narrow rear blood vessel is dominated
Cardiac muscle can necrosis and it is irreversible so that threat to life.
Currently, there are two types of therapeutic scheme it is available, one is percutaneous coronary intervention (pci) (PCI,
Percutaneous Coronary Intervention), another kind is that CABG or two kinds of therapeutic schemes are used in combination.
Both therapeutic schemes respectively have advantage and disadvantage, and PCI wound is smaller, and CABG then needs out chest or minimally invasive, and the bracket of PCI is outer after all
The material come, and it is easier to occur narrow, and CABG is put up a bridge using the blood vessel of patient itself, and long-term patency is relatively
It is excellent.
However, patient, after finishing operation, doctor can go the real-time streams of measurement bridge joint blood vessel to take temperature with the presence or absence of competition
Stream can also provide average flow rate, but there is no the postoperative effects that a parameter is used to predict or measure CABG；Thus may be used
To find out, the existing method without being used to predict or measure the postoperative effect for CABG.
Summary of the invention
In view of this, an embodiment of the present invention is intended to provide a kind of coronary artery bypass grafting determination method for parameter, device, electronic equipment
And computer storage medium, it is intended to realize the prediction or measurement to the postoperative effect of CABG.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows:
In a first aspect, the embodiment of the present invention provides a kind of coronary artery bypass grafting determination method for parameter, comprising:
According to the data of the coronary artery computed tomography radiography CTA got, it is reconstructed, obtains having narrow
The coronary artery of lesion, and determine outlet to be measured corresponding with the stenotic lesion；To the hat with stenotic lesion
Shape artery is repaired, and the coronary artery of no stenotic lesion is obtained；According to the impedance of the outlet to be measured, using preset fluid
Mechanics algorithm determines the blood flow total value of outlet to be measured described in the coronary artery of the no stenotic lesion；According to pre-
If coronary artery bypass grafting CABG scheme, the coronary artery with stenotic lesion is bridged, CABG is obtained
Coronary artery afterwards；Hat according to the impedance of the outlet to be measured, using the hydrodynamics algorithm, after determining the CABG
The blood flow total value of outlet to be measured described in shape artery；The outlet to be measured according to the coronary artery after the CABG
The blood flow total value of outlet to be measured described in the coronary artery of blood flow total value and the no stenotic lesion determines hat
Arteries and veins bridging parameter；Wherein, the coronary artery bypass grafting parameter is for characterizing the health degree coronarius after the CABG.
Further, the blood flow total value of outlet to be measured described in the coronary artery according to after the CABG and
The blood flow total value of outlet to be measured described in the coronary artery of the no stenotic lesion, determines coronary artery bypass grafting parameter, comprising:
It is coronal dynamic with the no stenotic lesion by the blood flow total value of outlet to be measured described in the coronary artery after the CABG
Ratio between the blood flow total value of outlet to be measured described in arteries and veins, is determined as the coronary artery bypass grafting parameter.
Further, it in the data according to the coronary artery computed tomography radiography CTA got, is reconstructed,
The coronary artery with stenotic lesion is obtained, and after determining outlet to be measured corresponding with the stenotic lesion, the side
Method further include: according to the impedance of the outlet to be measured, using the hydrodynamics algorithm, determine described with stenotic lesion
The blood flow total value of outlet to be measured described in coronary artery；According to the coronary artery with stenotic lesion to
Measure the blood flow summation of outlet to be measured described in the blood flow total value of mouth and the coronary artery of the no stenotic lesion
Value determines the state parameter coronarius with stenotic lesion；Wherein, the state parameter described has for characterizing
The severe degree coronarius of stenotic lesion.
Further, the blood flow of outlet to be measured described in the coronary artery according to stenotic lesion is total
With the blood flow total value of outlet to be measured described in the coronary artery of value and the no stenotic lesion, determine described with narrow
The state parameter coronarius of lesion, comprising: by the blood of outlet to be measured described in the coronary artery with stenotic lesion
Flow quantity total value, the ratio between the blood flow total value of outlet to be measured described in the coronary artery with the no stenotic lesion
Value determines the state parameter coronarius with stenotic lesion.
Further, the scheme according to preset coronary artery bypass grafting CABG has stenotic lesion to described
Coronary artery bridged, the coronary artery after obtaining CABG, comprising: put up a bridge the CABG of point with first inlet point and first
Scheme bridges the coronary artery with stenotic lesion, the coronary artery after obtaining the CABG；Wherein, described
First inlet point is located in internal mammary artery, and described first puts up a bridge point according to the direction of blood flow, is located under the stenotic lesion
On the coronary artery of side.
Further, the scheme according to preset Coronary artery bypass CABG, to the hat with stenotic lesion
Shape artery is bridged, the coronary artery after obtaining CABG, comprising: with the side of the second inlet point and the CABG of the second bridging point
Case bridges the coronary artery with stenotic lesion, the coronary artery after obtaining the CABG；Wherein, described
Two inlet points are located in internal mammary artery, and described second puts up a bridge point including two, according to the direction of blood flow, are located at described
On coronary artery on coronary artery below stenotic lesion and above the stenotic lesion.
Further, the scheme according to preset Coronary artery bypass CABG, to the hat with stenotic lesion
Shape artery is bridged, the coronary artery after obtaining CABG, comprising: with the scheme of the CABG of third bridging point, is had to described
The coronary artery of stenotic lesion is bridged, the coronary artery after obtaining the CABG；Wherein, the third bridging point includes two
It is a, according to the direction of blood flow, it is located on the coronary artery below the stenotic lesion and the stenotic lesion top
Coronary artery on.
Further, the scheme according to preset Coronary artery bypass CABG, to the hat with stenotic lesion
Shape artery is bridged, the coronary artery after obtaining CABG, comprising: with the side of third inlet point and the CABG of the 4th bridging point
Case bridges the coronary artery with stenotic lesion, the coronary artery after obtaining the CABG；Wherein, described
Triple feed inlet point is located on aorta ascendens, and the 4th bridging point is located under the stenotic lesion according to the direction of blood flow
On the coronary artery of side.
Second aspect, the embodiment of the present invention provide a kind of determining device of coronary artery bypass grafting parameter, comprising:
Reconstructed module carries out weight for the data according to the coronary artery computed tomography radiography CTA got
Structure obtains the coronary artery with stenotic lesion, and determines outlet to be measured corresponding with the stenotic lesion；Repair mould
Block obtains the coronary artery of no stenotic lesion for repairing to the coronary artery with stenotic lesion；First determines
Module determines the no stenotic lesion using preset hydrodynamics algorithm for the impedance according to the outlet to be measured
The blood flow total value of outlet to be measured described in coronary artery；Bridge module, for being moved according to preset coronary artery bypass
The scheme for planting CABG, bridges the coronary artery with stenotic lesion, the coronary artery after obtaining CABG；Second really
Cover half block, it is coronal after determining the CABG using the hydrodynamics algorithm for the impedance according to the outlet to be measured
The blood flow total value of outlet to be measured described in artery；Third determining module, for according to the coronary artery after the CABG
Described in outlet to be measured described in the blood flow total value of outlet to be measured and the coronary artery of the no stenotic lesion blood
Flow total value determines coronary artery bypass grafting parameter；Wherein, the coronary artery bypass grafting parameter is for characterizing the coronary artery after the CABG
Health degree.
Further, the third determining module, is specifically used for: by described in the coronary artery after the CABG wait measure
Mouthful blood flow total value, the blood flow total value of outlet to be measured described in the coronary artery with the no stenotic lesion it
Between ratio, be determined as the coronary artery bypass grafting parameter.
Further, described device further include: the 4th determining module is used for the impedance according to the outlet to be measured
The hydrodynamics algorithm determines the blood flow summation of outlet to be measured described in the coronary artery with stenotic lesion
Value；5th determining module, the blood flow for the outlet to be measured according to the coronary artery with stenotic lesion are total
With the blood flow total value of outlet to be measured described in the coronary artery of value and the no stenotic lesion, determine described with narrow
The state parameter coronarius of lesion；Wherein, the state parameter is used to characterize the coronary artery with stenotic lesion
Severe degree.
Further, the 5th determining module, is specifically used for: will be described in the coronary artery with stenotic lesion
The blood flow of the blood flow total value of outlet to be measured, outlet to be measured described in the coronary artery with the no stenotic lesion is total
Ratio between value determines the state parameter coronarius with stenotic lesion.
Further, the bridge module, is specifically used for: with the first inlet point and first put up a bridge point CABG scheme,
The coronary artery with stenotic lesion is bridged, the coronary artery after obtaining the CABG；Wherein, described first into
Mouthful point is located in internal mammary artery, and described first puts up a bridge direction of the point according to blood flow, hat below the stenotic lesion
On shape artery.
Further, the bridge module, is specifically used for: with the second inlet point and second put up a bridge point CABG scheme,
The coronary artery with stenotic lesion is bridged, the coronary artery after obtaining the CABG；Wherein, described second into
Mouth point is located in internal mammary artery, and described second puts up a bridge point including two, according to the direction of blood flow, is located at described narrow
On coronary artery on coronary artery below lesion and above the stenotic lesion.
Further, the bridge module, is specifically used for: with the scheme of the CABG of third bridging point, to described with narrow
The coronary artery of narrow lesion is bridged, the coronary artery after obtaining the CABG；Wherein, the third bridging point includes two
It is a, according to the direction of blood flow, it is located on the coronary artery below the stenotic lesion and the stenotic lesion top
Coronary artery on.
Further, the bridge module, is specifically used for: with third inlet point and the 4th put up a bridge point CABG scheme,
The coronary artery with stenotic lesion is bridged, the coronary artery after obtaining the CABG；Wherein, the third into
Mouth point is located on aorta ascendens, and the 4th bridging point is located at below the stenotic lesion according to the direction of blood flow
On coronary artery.
The third aspect, the embodiment of the present invention provide a kind of electronic equipment, the electronic equipment include processor, memory and
Communication bus；The communication bus is for realizing the connection communication between processor and memory；The processor is for executing
The determination program of the coronary artery bypass grafting parameter stored in memory, to perform the steps of
According to the data of the coronary artery computed tomography radiography CTA got, it is reconstructed, obtains having narrow
The coronary artery of lesion, and determine outlet to be measured corresponding with the stenotic lesion；To the hat with stenotic lesion
Shape artery is repaired, and the coronary artery of no stenotic lesion is obtained；According to the impedance of the outlet to be measured, using preset fluid
Mechanics algorithm determines the blood flow total value of outlet to be measured described in the coronary artery of the no stenotic lesion；According to pre-
If coronary artery bypass grafting CABG scheme, the coronary artery with stenotic lesion is bridged, CABG is obtained
Coronary artery afterwards；Hat according to the impedance of the outlet to be measured, using the hydrodynamics algorithm, after determining the CABG
The blood flow total value of outlet to be measured described in shape artery；The outlet to be measured according to the coronary artery after the CABG
The blood flow total value of outlet to be measured described in the coronary artery of blood flow total value and the no stenotic lesion determines hat
Arteries and veins bridging parameter；Wherein, the coronary artery bypass grafting parameter is for characterizing the health degree coronarius after the CABG.
Further, the blood flow total value of outlet to be measured described in the coronary artery according to after the CABG and
The blood flow total value of outlet to be measured described in the coronary artery of the no stenotic lesion, determines in coronary artery bypass grafting parameter, institute
The determination program that processor is also used to execute the coronary artery bypass grafting parameter is stated, to perform the steps of the hat after the CABG
The blood flow total value of outlet to be measured described in shape artery, outlet to be measured described in the coronary artery with the no stenotic lesion
Blood flow total value between ratio, be determined as the coronary artery bypass grafting parameter.
Further, it in the data according to the coronary artery computed tomography radiography CTA got, is reconstructed,
The coronary artery with stenotic lesion is obtained, and after determining outlet to be measured corresponding with the stenotic lesion, the place
Reason device is also used to execute the determination program of the coronary artery bypass grafting parameter, to perform the steps of the resistance according to the outlet to be measured
It is anti-, using the hydrodynamics algorithm, determine the blood of outlet to be measured described in the coronary artery with stenotic lesion
Flow total value；The blood flow total value of the outlet to be measured according to the coronary artery with stenotic lesion and described
The blood flow total value of outlet to be measured described in coronary artery without stenotic lesion determines described coronal with stenotic lesion
The state parameter of artery；Wherein, the state parameter is used to characterize the severe degree coronarius with stenotic lesion.
Further, the blood flow of outlet to be measured described in the coronary artery according to stenotic lesion is total
With the blood flow total value of outlet to be measured described in the coronary artery of value and the no stenotic lesion, determine described with narrow
In the state parameter coronarius of lesion, the processor is also used to execute the determination program of the coronary artery bypass grafting parameter, with
It performs the steps of the blood flow total value of outlet to be measured described in the coronary artery with stenotic lesion, with institute
State the ratio between the blood flow total value of outlet to be measured described in the coronary artery of no stenotic lesion, determine it is described have it is narrow
The state parameter coronarius of narrow lesion.
Further, the scheme according to preset coronary artery bypass grafting CABG has stenotic lesion to described
Coronary artery bridged, the coronary artery after obtaining CABG, the processor is also used to execute the coronary artery bypass grafting parameter
Determination program, with perform the steps of with the first inlet point and first put up a bridge point CABG scheme, to it is described have it is narrow
The coronary artery of lesion is bridged, the coronary artery after obtaining the CABG；Wherein, first inlet point is located in cream and moves
On arteries and veins, the direction according to blood flow is put in first bridging, on the coronary artery below the stenotic lesion.
Further, the scheme according to preset coronary artery bypass grafting CABG has stenotic lesion to described
Coronary artery bridged, the coronary artery after obtaining CABG, the processor is also used to execute the coronary artery bypass grafting parameter
Determination program, with perform the steps of with the second inlet point and second put up a bridge point CABG scheme, to it is described have it is narrow
The coronary artery of lesion is bridged, the coronary artery after obtaining the CABG；Wherein, second inlet point is located in cream and moves
On arteries and veins, described second puts up a bridge point including two, according to the direction of blood flow, is located at coronal below the stenotic lesion
On coronary artery on artery and above the stenotic lesion.
Further, the scheme according to preset coronary artery bypass grafting CABG has stenotic lesion to described
Coronary artery bridged, the coronary artery after obtaining CABG, the processor is also used to execute the coronary artery bypass grafting parameter
Determination program, with perform the steps of with third put up a bridge point CABG scheme, to described coronal dynamic with stenotic lesion
Arteries and veins is bridged, the coronary artery after obtaining the CABG；Wherein, the third puts up a bridge point including two, according to blood flow
Direction, be located on the coronary artery below the stenotic lesion and the stenotic lesion above coronary artery on.
Further, the scheme according to preset coronary artery bypass grafting CABG has stenotic lesion to described
Coronary artery bridged, the coronary artery after obtaining CABG, the processor is also used to execute the coronary artery bypass grafting parameter
Determination program, with perform the steps of with third inlet point and the 4th put up a bridge point CABG scheme, to it is described have it is narrow
The coronary artery of lesion is bridged, the coronary artery after obtaining the CABG；Wherein, the third inlet point, which is located at, rises actively
On arteries and veins, the 4th bridging point is located on the coronary artery below the stenotic lesion according to the direction of blood flow.
Fourth aspect, the embodiment of the present invention provide a kind of computer storage medium, store in the computer storage medium
There are computer executable instructions, which is configured to execute the hat provided in said one or multiple embodiments
Arteries and veins bridging determination method for parameter.
A kind of coronary artery bypass grafting determination method for parameter, device provided by the embodiment of the present invention, electronic equipment and computer
Storage medium, this method comprises: obtaining having narrow firstly, be reconstructed according to the data of the coronary angiography with CT got
The coronary artery of lesion, and determine outlet to be measured corresponding with stenotic lesion, to the coronary artery with stenotic lesion into
Row is repaired, and obtains the coronary artery of no stenotic lesion, according to the impedance of outlet to be measured, using preset hydrodynamics algorithm, really
The blood flow total value for making outlet to be measured in the coronary artery of no stenotic lesion, according to the scheme of preset CABG, to tool
There is the coronary artery of stenotic lesion to be bridged, obtain the coronary artery of CABG, according to the impedance of outlet to be measured, using fluid force
Algorithm is learned, the blood flow total value of outlet to be measured in the coronary artery after determining CABG, according to the coronary artery after CABG
In outlet to be measured described in the blood flow total value of outlet to be measured and the coronary artery of the no stenotic lesion blood flow
Total value determines coronary artery bypass grafting parameter, wherein coronary artery bypass grafting parameter is for characterizing the health degree coronarius after CABG；
That is, in embodiments of the present invention, by the coronary artery with stenotic lesion reconstructed, to coronal after CABG
Artery, the blood flow total value of outlet to be measured in the coronary artery after CABG can be determined according to hydrodynamics algorithm, and
And the coronary artery of no stenotic lesion is determined according to hydrodynamics algorithm to the coronary artery without stenotic lesion after reparation
In outlet to be measured blood flow total value, on this basis, according to the blood stream of outlet to be measured in the coronary artery after CABG
The blood flow total value for measuring outlet to be measured in total value and coronary artery without stenotic lesion, determines coronary artery bypass grafting parameter, this
Sample, with the ginseng of outlet to be measured in the parameter of the outlet to be measured in the coronary artery after CABG and the coronary artery without stenotic lesion
Number, to determine coronary artery bypass grafting parameter, so that coronary artery bypass grafting parameter can reflect the health degree coronarius after CABG, such as
This, coronary artery bypass grafting parameter is used to predict or measure the postoperative effect for CABG, provides one for the implementation of the scheme of CABG
With reference to so that being conducive to medical worker is that patient brakes therapeutic scheme.
Detailed description of the invention
Fig. 1 is the flow diagram of the coronary artery bypass grafting determination method for parameter in the embodiment of the present invention；
Fig. 2 is the structural schematic diagram of the first optional example coronarius in the embodiment of the present invention；
Fig. 3 is the distribution schematic diagram of second of optional example coronarius in the embodiment of the present invention；
Fig. 4 is the structural schematic diagram of the third optional example coronarius in the embodiment of the present invention；
Fig. 5 is the structural schematic diagram of the 4th kind of optional example coronarius in the embodiment of the present invention；
Fig. 6 is the structural schematic diagram of the 5th kind of optional example coronarius in the embodiment of the present invention；
Fig. 7 is the structural schematic diagram of the 6th kind of optional example coronarius in the embodiment of the present invention；
Fig. 8 is the structural schematic diagram of the 7th kind of optional example coronarius in the embodiment of the present invention；
Fig. 9 is the structural schematic diagram of the determining device of the coronary artery bypass grafting parameter in the embodiment of the present invention；
Figure 10 is the structural schematic diagram of the electronic equipment in the embodiment of the present invention；
Figure 11 is the structural schematic diagram of the computer storage medium in the embodiment of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description.
The embodiment of the present invention provides a kind of coronary artery bypass grafting determination method for parameter, and this method can be applied to electronic equipment
In, Fig. 1 is the flow diagram of the coronary artery bypass grafting determination method for parameter in the embodiment of the present invention, as shown in Figure 1, the coronary artery is taken
Bridge determination method for parameter may include:
S101: according to the data of the coronary angiography with CT got, being reconstructed, and obtains having the coronal dynamic of stenotic lesion
Arteries and veins, and determine outlet to be measured corresponding with stenotic lesion；
Currently, doctor can remove the real-time traffic of measurement bridge joint blood vessel, according to real-time traffic after finishing CABG operation
Come determine whether there is competition stream, average flow rate can also be counted, can also by measurement Coronary Blood Flow Reserve score (FFR,
Fractional Flow Reserve), the case where for assessing myocardial ischemia.
However, above-mentioned parameter can not accurately assess the postoperative effect of CABG, then, in order to preferably assess CABG
Postoperative effect, firstly, obtaining coronary artery computed tomography radiography (CTA, Computed Tomographic
Angiography), medical digital is obtained by coronary artery CTA and be imaged and communicate (DICOM, Digital Imaging and
Communications in Medicine) data, be based on above-mentioned DICOM data reconstruction coronary artery, it is available have it is narrow
The coronary artery of lesion.
Here, it should be noted that the obtained coronary artery with stenotic lesion can only have stenotic lesion at one,
There can be many places stenotic lesion, here, the embodiment of the present invention is not especially limited.
Fig. 2 is the structural schematic diagram of the first optional example coronarius in the embodiment of the present invention, with reference to Fig. 2 institute
Show, depict coronary artery with curve, the impedance value of each outlet and each outlet has been marked with the number, has included in Fig. 2
Coronary artery entrance, outlet 111, outlet 1121, outlet 1122, outlet 12, outlet 211, outlet 2121, outlet 212211, outlet
212212, outlet 21222 and outlet 22；Wherein, the impedance value for exporting 111 is 474750dynes.s/cm5, export 1121 resistance
Anti- value is 186684dynes.s/cm5, the impedance value for exporting 1122 is 1025787dynes.s/cm5, exporting 12 impedance value is
414894dynes.s/cm5, the impedance value for exporting 211 is 395474dynes.s/cm5, exporting 2121 impedance value is
740105dynes.s/cm5, the impedance value for exporting 212211 is 741175dynes.s/cm5, exporting 212212 impedance value is
573635dynes.s/cm5, the impedance value for exporting 21222 is 505158dynes.s/cm5, exporting 22 impedance value is
713167dynes.s/cm5。
Fig. 3 is the structural schematic diagram of second of optional example coronarius in the embodiment of the present invention, the left side in Fig. 3
Side is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；Refering to what is shown in Fig. 3, right side is that can obtain by reconstruct
The coronary artery FFR with 91% stenotic lesion arrivedCTACloud atlas can after obtaining that there is the coronary artery of stenotic lesion
To determine outlet that stenotic lesion is influenced, that is to say, that the lectin from hemolymph influenced whether by the presence of the stenotic lesion
The outlet of change, the outlet are outlet to be measured corresponding with stenotic lesion.
As can be seen from Figure 3 the position of stenotic lesion, it will thus be seen that the stenotic lesion can cause 1121 and 1122
The blood flow of two outlets changes, so, the number of outlet to be measured is 1121 and 1122.
S102: repairing the coronary artery with stenotic lesion, obtains the coronary artery of no stenotic lesion；
S103: the coronal of no stenotic lesion is determined using preset hydrodynamics algorithm according to the impedance of outlet to be measured
The blood flow total value of outlet to be measured in artery；
For by taking the coronary artery of single stenotic lesion as an example, after obtaining that there is the coronary artery of stenotic lesion, need
Fluid Mechanics Computation (CFD, Computational Fluid Dynamics) is carried out to the coronary artery of single stenotic lesion
Analysis, the blood flow of available all outlet ports is analyzed by CFD.
Specifically, when carrying out CFD numerical simulation, the inlet pressure of coronary artery gives 90mmHg, outlet i coronarius
Pressure PiWith outlet i flow QiFollowing formula need to be met:
Pi=QiRi+Pv (1)
Wherein, RiFor the impedance for exporting i, PvFor center vein pressure, it is 6.25mmHg, indicates exit numbers with i；Flowing
Medium be blood, density 1060kg/m3, viscosity 0.0035kg/ms；Model uses laminar flow, can not press, and SIMPLE is calculated
Method, vascular wall is indeformable, i.e., without fluid and structural simulation；All examples are all based on above-mentioned simulation bar in the embodiment of the present invention
Part.
That is, according to the impedance of outlet to be measured, being calculated using hydrodynamics in the case where knowing above-mentioned simulated conditions
Method, for example, semi-implicit method (SIMPLE, Semi-Implicit Method for Pressure of coupling pressure equation group
Linked Equations), the blood flow of outlet to be measured, more when having in the available coronary artery with stenotic lesion
When a outlet to be measured, it is added the blood flow of multiple outlets to be measured to obtain blood flow total value.
In order to learn the severe degree coronarius with stenotic lesion, in an alternative embodiment, S101 it
Afterwards, this method further include:
According to the impedance of outlet to be measured, using hydrodynamics algorithm, determine to have in the coronary artery of stenotic lesion to
Measure the blood flow total value of mouth；
According to the blood flow total value of outlet to be measured in the coronary artery with stenotic lesion and without the hat of stenotic lesion
The blood flow total value of outlet to be measured in shape artery, determining has the state parameter coronarius of stenotic lesion；Wherein, shape
State parameter is used to characterize the severe degree coronarius with stenotic lesion.
Fig. 4 is the structural schematic diagram of the third optional example coronarius in the embodiment of the present invention, the left side in Fig. 4
Side is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；Refering to what is shown in Fig. 4, to the coronal of stenotic lesion
Artery is repaired, and normal coronary artery is repaired into, is the coronary artery of above-mentioned no stenotic lesion on the right side of Fig. 4, similarly,
According to above-mentioned simulated conditions, the coronary artery of no stenotic lesion is determined using SIMPLE algorithm according to the impedance of outlet to be measured
In outlet to be measured blood flow total value, in this way, can be according to the blood of outlet to be measured in the coronary artery with stenotic lesion
The blood flow total value of outlet to be measured in flow quantity total value and coronary artery without stenotic lesion, determining has stenotic lesion
State parameter coronarius, with reflect have stenotic lesion severe degree coronarius.
In order to more accurately reflect the severe degree coronarius with stenotic lesion, in a kind of optional implementation
It is coronal dynamic according to the blood flow total value of outlet to be measured in the coronary artery with stenotic lesion and without stenotic lesion in example
The blood flow total value of outlet to be measured in arteries and veins, determining has the state parameter coronarius of stenotic lesion, may include:
It is coronal with no stenotic lesion by the blood flow total value of outlet to be measured in the coronary artery with stenotic lesion
Ratio in artery between the blood flow total value of outlet to be measured is determined as having the state coronarius of stenotic lesion to join
Number.
That is, state parameter is a nondimensional index, can reflect by the size of ratio provided it is narrow
The severe degree coronarius of lesion, ratio is smaller, illustrates that the degree of stenotic lesion is worse, and ratio is bigger, illustrates narrow
The degree of lesion is not very serious.
For example, being repaired for single narrow coronary artery, the coronary artery at no stenotic lesion, i.e. normal coronary artery are repaired, then
It carries out CFD and analyzes the blood flow total value of outlet to be measured in the coronary artery of available above-mentioned no stenotic lesion to be QN；In this way, can
It is as follows with definition status parameter:
Wherein, QSBlood flow total value of the expression with outlet to be measured in the coronary artery of stenotic lesion；Above-mentioned state
Parameter is a dimensionless number, if the value closer to 1, shows that this stenotic lesion is not serious, myocardium more not ischemic；If should
Value shows that this stenotic lesion is more serious closer to 0, and cardiac muscle gets over ischemic.
S104: according to the scheme of preset CABG, the coronary artery with stenotic lesion is bridged, after obtaining CABG
Coronary artery；
In order to determine the coronary artery bypass grafting parameter coronarius after CABG, firstly, it is necessary to the coronal of stenotic lesion
Artery, is bridged according to the scheme of preset CABG, the coronary artery after obtaining CABG.Wherein, according to preset CABG's
Scheme bridges the coronary artery with stenotic lesion, can be realized by any one following mode:
In an alternative embodiment, S104 may include:
With the scheme of the first inlet point and the CABG of the first bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；
Wherein, the first inlet point is located in internal mammary artery, and first puts up a bridge point according to the direction of blood flow, is located at narrow disease
Become on the coronary artery of lower section.
Specifically, Fig. 5 is the structural schematic diagram of the 4th kind of optional example coronarius in the embodiment of the present invention,
Left side in Fig. 5 is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；With reference to the right side of Fig. 5, internal mammary artery
Inlet point and its direction it is known that draw the straight line of a 10mm in the direction；Bridging point after narrow is also selected, then the side to put up a bridge a little
To it is also known that, can determine a plane using the direction and coronary artery central point, the straight line of a 10mm long can be drawn in the plane with taking
The direction of bridge point is at 15 degree of angles；A space curve is drawn between this two straight lines guarantees the space curve and this two diameters in intersection point
Curvature is equal；The diameter of specified inlet point is 2mm, gradual change to bridging point 1.6mm (above-mentioned specific value can all be adjusted)；Such as
This, the blood vessel of internal mammary artery have been established also overlapped it is narrow after coronary artery realize bridging mode A, which is also common for doctor
Bridging mode.
In an alternative embodiment, S104 may include:
With the scheme of the second inlet point and the CABG of the second bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；
Wherein, the second inlet point is located in internal mammary artery, and the second point of putting up a bridge includes two, according to the direction of blood flow,
It is located on the coronary artery on the coronary artery below stenotic lesion and above stenotic lesion.
Specifically, Fig. 6 is the structural schematic diagram of the 5th kind of optional example coronarius in the embodiment of the present invention,
Left side in Fig. 6 is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；With reference to the right side of Fig. 6, in Fig. 5
Increase a semicircle in inlet point and two straight lines of point of putting up a bridge to be connected by it with narrow preceding coronary artery, connected area is about bridging blood
Twice of pipe area；Two space curves connection semicircles of same addition and two sections of straight lines just now, 4 tie point songs of same guarantee
Rate is equal；In addition diameter information, import spot diameter 2mm, the point 1.6mm that puts up a bridge can produce bridge blood vessel, realize bridging mode B.
In an alternative embodiment, S104 may include:
With the scheme of the CABG of third bridging point, the coronary artery with stenotic lesion is bridged, after obtaining CABG
Coronary artery；
Wherein, third puts up a bridge point including two, according to the direction of blood flow, is located at coronal below stenotic lesion
On coronary artery on artery and above stenotic lesion.
Specifically, Fig. 7 is the structural schematic diagram of the 6th kind of optional example coronarius in the embodiment of the present invention,
Left side in Fig. 7 is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；It is narrow in coronary artery with reference to the right side of Fig. 7
Narrow front and back respectively selects a point as the bridging point of bridge joint blood vessel, is equally formed in coronary artery central point and two direction for putting up a bridge point
Two planes in respectively do a 10mm and the straight line with the direction of coronary artery bypass grafting point at 15 degree of angles, connection put up a bridge point straight line gernertion it is empty
Half interval contour guarantees that the curvature of two tie points is equal, and since bridge joint blood vessel is shorter, just the diameter of bridge joint blood vessel is defined as here
2mm is achieved in bridging mode C.
In an alternative embodiment, S104 may include:
With the scheme of third inlet point and the CABG of the 4th bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；
Wherein, third inlet point is located on aorta ascendens, and the 4th bridging point is located at narrow disease according to the direction of blood flow
Become on the coronary artery of lower section.
Specifically, Fig. 8 is the structural schematic diagram of the 7th kind of optional example coronarius in the embodiment of the present invention,
Left side in Fig. 8 is FFRCTAExample parameter deck watch, range be 0.7 to 1.0 between；Right side and doctor with reference to Fig. 8
A kind of common bridging mode opens an openning as the inlet point of bridge blood vessel, one normal side of same work on aorta ascendens
The straight line gernertion space curve of the straight line of upward 10mm, connection bridging point guarantees that the curvature of two tie points is equal, due to bridge joint
Blood vessel is shorter, and the diameter of bridge joint blood vessel is just defined as 2mm here, is achieved in bridging mode D.
S105: to be measured in the coronary artery after determining CABG using hydrodynamics algorithm according to the impedance of outlet to be measured
The blood flow total value of outlet；
Similarly, using above-mentioned simulated conditions, the blood stream of outlet to be measured in the coronary artery after can determining CABG
Total value is measured, in this manner it is possible to the case where learning the blood flow of outlet to be measured in the coronary artery after CABG.
S106: according to the blood flow total value of outlet to be measured in the coronary artery after CABG and without the coronal of stenotic lesion
The blood flow total value of outlet to be measured, determines coronary artery bypass grafting parameter in artery；
Wherein, coronary artery bypass grafting parameter is for characterizing the health degree coronarius after CABG.
In learning the coronary artery after CABG the case where the blood flow of outlet to be measured after, can be by CABG after
In coronary artery in the blood flow total value of outlet to be measured and the coronary artery without stenotic lesion outlet to be measured blood flow
Total value determines coronary artery bypass grafting parameter, to reflect the health degree coronarius after CABG.
In order to understand the health degree coronarius after CABG, in an alternative embodiment, S105 may include:
It will be in the blood flow total value of outlet to be measured in the coronary artery after CABG, with the coronary artery of no stenotic lesion
Ratio between the blood flow total value of outlet to be measured, is determined as coronary artery bypass grafting parameter.
Specifically, to there is single narrow coronary artery to carry out various forms of bridgings, it is available that CFD analysis is carried out again
After CABG in coronary artery outlet to be measured blood flow total value QB, then, coronary artery bypass grafting parameter can pass through following equation
To calculate:
The effect of CABG is characterized with above-mentioned calculated coronary artery bypass grafting parameter, if the bigger (dimensionless at this time of the value
Number is possible to greater than 1, this illustrate CABG postoperative blood supply situation than normal blood vessels blood supply also than get well), show that CABG effect is got over
It is good, if the value is closerThen show that the effect of CABG is poorer.
For by taking above-mentioned Fig. 3-Fig. 8 as an example, CFD numerical simulation is carried out using the coronary artery in Fig. 3 and Fig. 4, can be obtained
Into the coronary artery with stenotic lesion it is to be measured outlet 1121 and 1122 blood flow total value be 16.13mL/min, nothing
In the coronary artery of stenotic lesion it is to be measured outlet 1121 and 1122 blood flow total value be 152.50mL/min, therefore,
After the bridging mode A in Fig. 5, it is same carry out CFD numerical simulation and can obtain CABG after coronary artery in
The blood flow summation for measuring mouth 1121 and 1122 is 89.93mL/min, therefore, bridging mode A's
After the bridging mode B in Fig. 6, carrying out CFD numerical simulation can be obtained in the coronary artery after CABG wait measure
1121 and 1122 blood flow summations of mouth are 120.02mL/min, can also calculate bridging mode B's
After the bridging mode C in Fig. 7, carrying out CFD numerical simulation can be obtained in the coronary artery after CABG wait measure
1121 and 1122 blood flow summations of mouth are 138.56mL/min, can also calculate bridging mode C's
After the bridging mode D in Fig. 8, carrying out CFD numerical simulation can be obtained in the coronary artery after CABG wait measure
1121 and 1122 blood flow summations of mouth are 130.76mL/min, can also calculate bridging mode D's
In conclusion all examples have the coronary artery of single 91% stenosis rate, bridging mode such as without the coronary artery of stenotic lesion
Each entrance flow of the CFD numerical simulation of A, bridging mode B, bridging mode C and bridging mode D is as shown in table 1 below:
Table 1
In table 1 above, coronary artery bypass grafting parameter and this dimensionless number of state parameter are also enumerated in last line.
Here, there are commonly bridging mode A and bridging mode D by doctor, and the effect of bridging mode A is not very excellent, relatively
For bridging mode D it is preferable, compare four kinds of bridging modes, bridging mode C is optimal, and required bridge blood vessel is also most short.
A kind of coronary artery bypass grafting determination method for parameter provided by the embodiment of the present invention, this method comprises: firstly, according to obtaining
The data for the coronary angiography with CT got, are reconstructed, and obtain the coronary artery with stenotic lesion, and determine and narrow disease
Covert corresponding outlet to be measured, repairs the coronary artery with stenotic lesion, obtains the coronary artery of no stenotic lesion,
It is determined in the coronary artery of no stenotic lesion using preset hydrodynamics algorithm wait measure according to the impedance of outlet to be measured
The blood flow total value of mouth bridges the coronary artery with stenotic lesion, obtains according to the scheme of preset CABG
The coronary artery of CABG, according to the impedance of outlet to be measured, using hydrodynamics algorithm, in the coronary artery after determining CABG to
The blood flow total value for measuring mouth, according to the blood flow total value and the nothing of outlet to be measured in the coronary artery after CABG
The blood flow total value of outlet to be measured described in the coronary artery of stenotic lesion, determines coronary artery bypass grafting parameter, wherein coronary artery is taken
Bridge parameter is for characterizing the health degree coronarius after CABG；That is, in embodiments of the present invention, by reconstruct
The coronary artery with stenotic lesion out can determine CABG according to hydrodynamics algorithm to the coronary artery after CABG
The blood flow total value of outlet to be measured in coronary artery afterwards, also, to the coronary artery without stenotic lesion after reparation, it presses
According to hydrodynamics algorithm, the blood flow total value of outlet to be measured in the coronary artery of no stenotic lesion is determined, it is basic herein
On, according to be measured in the blood flow total value of outlet to be measured in the coronary artery after CABG and the coronary artery without stenotic lesion
The blood flow total value of outlet, determines coronary artery bypass grafting parameter, in this way, with the ginseng of the outlet to be measured in the coronary artery after CABG
Several parameters with outlet to be measured in the coronary artery without stenotic lesion, to determine coronary artery bypass grafting parameter, so that coronary artery bypass grafting parameter
Health degree coronarius after can reflect CABG, in this way, coronary artery bypass grafting parameter is used to predict or measure for CABG
Postoperative effect, provide a reference for the implementation of the scheme of CABG, thus be conducive to medical worker be patient brake treatment
Scheme.
Based on the same inventive concept, the present embodiment provides a kind of determining device of coronary artery bypass grafting parameter, Fig. 9 is that the present invention is real
The structural schematic diagram for applying the determining device of the coronary artery bypass grafting parameter in example is repaired as shown in figure 9, the device includes: reconstructed module 91
Multiple module 92, the first determining module 93, bridge module 94, the second determining module 95 and third determining module 96；
Wherein, reconstructed module 91 are reconstructed for the data according to the coronary angiography with CT got, obtain having narrow
The coronary artery of narrow lesion, and determine outlet to be measured corresponding with stenotic lesion；Repair module 92, for narrow
The coronary artery of lesion is repaired, and the coronary artery of no stenotic lesion is obtained；First determining module 93, for according to wait measure
Mouthful impedance the blood stream of outlet to be measured in the coronary artery of no stenotic lesion is determined using preset hydrodynamics algorithm
Measure total value；Bridge module 94 carries out bridge to the coronary artery with stenotic lesion for the scheme according to preset CABG
It connects, the coronary artery after obtaining CABG；Second determining module 95 is calculated for the impedance according to outlet to be measured using hydrodynamics
Method, the blood flow total value of outlet to be measured in the coronary artery after determining CABG；Third determining module 96 is used for basis
Outlet to be measured in the blood flow total value of outlet to be measured and the coronary artery without stenotic lesion in coronary artery after CABG
Blood flow total value determines coronary artery bypass grafting parameter；
Wherein, coronary artery bypass grafting parameter is for characterizing the health degree coronarius after CABG.
In an alternative embodiment, third determining module 96 is specifically used for:
It will be in the blood flow total value of outlet to be measured in the coronary artery after CABG, with the coronary artery of no stenotic lesion
Ratio between the blood flow total value of outlet to be measured, is determined as coronary artery bypass grafting parameter.
In an alternative embodiment, the device further include:
4th determining module, for being reconstructed, obtaining having narrow in the data according to the coronary angiography with CT got
The coronary artery of narrow lesion, and after determining outlet to be measured corresponding with stenotic lesion, according to the impedance of outlet to be measured, adopt
With hydrodynamics algorithm, determine to have the blood flow total value of outlet to be measured in the coronary artery of stenotic lesion；5th really
Cover half block, for the blood flow total value according to outlet to be measured in the coronary artery with stenotic lesion and without stenotic lesion
The blood flow total value of outlet to be measured in coronary artery, determining has the state parameter coronarius of stenotic lesion；Wherein,
State parameter is used to characterize the severe degree coronarius with stenotic lesion.
In an alternative embodiment, the 5th determining module is specifically used for:
It is coronal with no stenotic lesion by the blood flow total value of outlet to be measured in the coronary artery with stenotic lesion
Ratio in artery between the blood flow total value of outlet to be measured determines that the state coronarius with stenotic lesion is joined
Number.
In an alternative embodiment, bridge module is specifically used for:
With the scheme of the first inlet point and the CABG of the first bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, the first inlet point is located in internal mammary artery, and first puts up a bridge point according to blood flow
Direction, on the coronary artery below stenotic lesion.
In an alternative embodiment, bridge module is specifically used for:
With the scheme of the second inlet point and the CABG of the second bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, the second inlet point is located in internal mammary artery, and the second bridging point includes two, according to
The direction of blood flow is located on the coronary artery on the coronary artery below stenotic lesion and above stenotic lesion.
In an alternative embodiment, bridge module is specifically used for:
With the scheme of the CABG of third bridging point, the coronary artery with stenotic lesion is bridged, after obtaining CABG
Coronary artery；Wherein, third puts up a bridge point including two, according to the direction of blood flow, is located at below stenotic lesion
On coronary artery on coronary artery and above stenotic lesion.
In an alternative embodiment, bridge module is specifically used for:
With the scheme of third inlet point and the CABG of the 4th bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, third inlet point is located on aorta ascendens, and the 4th puts up a bridge point according to blood flow
Direction be located on the coronary artery below stenotic lesion.
In practical applications, above-mentioned reconstructed module 91, repair module 92, the first determining module 93, bridge module 94, second
Determining module 95, third determining module 96, the 4th determining module and the 5th determining module can be real by the processor being located on device
Show, specially central processing unit (CPU, Central Processing Unit), microprocessor (MPU, Microprocessor
Unit), digital signal processor (DSP, Digital Signal Processing) or field programmable gate array (FPGA,
Field Programmable Gate Array) etc. realize.
Based on the same inventive concept, the present embodiment provides a kind of electronic equipment, Figure 10 is the electronics in the embodiment of the present invention
The structural schematic diagram of equipment, as shown in Figure 10, the electronic equipment include: processor 101, memory 102 and communication bus 103；
Wherein, communication bus 103 is for realizing the connection communication between processor 101 and memory 102；The processor 101 is used for
The determination program of the coronary artery bypass grafting parameter stored in memory is executed, to perform the steps of
It according to the data of the coronary angiography with CT got, is reconstructed, obtains the coronary artery with stenotic lesion, and
Determine outlet to be measured corresponding with stenotic lesion；Coronary artery with stenotic lesion is repaired, is obtained without narrow
The coronary artery of lesion；The hat of no stenotic lesion is determined using preset hydrodynamics algorithm according to the impedance of outlet to be measured
The blood flow total value of outlet to be measured in shape artery；According to the scheme of preset CABG, to coronal dynamic with stenotic lesion
Arteries and veins is bridged, the coronary artery after obtaining CABG；It is determined according to the impedance of outlet to be measured using hydrodynamics algorithm
The blood flow total value of outlet to be measured in coronary artery after CABG；According to the blood of outlet to be measured in the coronary artery after CABG
The blood flow total value of outlet to be measured, determines that coronary artery bypass grafting is joined in flow quantity total value and coronary artery without stenotic lesion
Number；Wherein, coronary artery bypass grafting parameter is for characterizing the health degree coronarius after CABG.
In an alternative embodiment, in the coronary artery according to after CABG outlet to be measured blood flow summation
The blood flow total value of outlet to be measured, determines in coronary artery bypass grafting parameter, the place in value and the coronary artery without stenotic lesion
Reason device 101 is also used to execute the determination program of the coronary artery bypass grafting parameter, to perform the steps of
It will be in the blood flow total value of outlet to be measured in the coronary artery after CABG, with the coronary artery of no stenotic lesion
Ratio between the blood flow total value of outlet to be measured, is determined as coronary artery bypass grafting parameter.
In an alternative embodiment, in the number according to the coronary artery computed tomography radiography CTA got
According to being reconstructed, obtain the coronary artery with stenotic lesion, and determine outlet to be measured corresponding with stenotic lesion
Afterwards, the processor 101 is also used to execute the determination program of the coronary artery bypass grafting parameter, to perform the steps of
The coronary artery with stenotic lesion is determined using the hydrodynamics algorithm according to the impedance of outlet to be measured
In outlet to be measured blood flow total value；According to the blood flow summation of outlet to be measured in the coronary artery with stenotic lesion
The blood flow total value of outlet to be measured in value and the coronary artery without stenotic lesion, determining has the coronary artery of stenotic lesion
State parameter；Wherein, state parameter is used to characterize the severe degree coronarius with stenotic lesion.
In an alternative embodiment, blood stream of the basis with outlet to be measured in the coronary artery of stenotic lesion
The blood flow total value of outlet to be measured in total value and coronary artery without stenotic lesion is measured, determining has the hat of stenotic lesion
In the state parameter of shape artery, the processor 101 is also used to execute the determination program of the coronary artery bypass grafting parameter, with realize with
Lower step:
It is coronal with no stenotic lesion by the blood flow total value of outlet to be measured in the coronary artery with stenotic lesion
Ratio in artery between the blood flow total value of outlet to be measured determines that the state coronarius with stenotic lesion is joined
Number.
In an alternative embodiment, the scheme according to preset CABG, to coronal dynamic with stenotic lesion
Arteries and veins is bridged, and in the coronary artery after obtaining CABG, the processor 101 is also used to execute the coronary artery bypass grafting parameter really
Program is determined, to perform the steps of
With the scheme of the first inlet point and the CABG of the first bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, the first inlet point is located in internal mammary artery, and first puts up a bridge point according to blood flow
Direction, on the coronary artery below stenotic lesion.
In an alternative embodiment, the scheme according to preset CABG, to coronal dynamic with stenotic lesion
Arteries and veins is bridged, and in the coronary artery after obtaining CABG, the processor 101 is also used to execute the coronary artery bypass grafting parameter really
Program is determined, to perform the steps of
With the scheme of the second inlet point and the CABG of the second bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, the second inlet point is located in internal mammary artery, and the second bridging point includes two, according to
The direction of blood flow is located on the coronary artery on the coronary artery below stenotic lesion and above stenotic lesion.
In an alternative embodiment, the scheme according to preset CABG, to coronal dynamic with stenotic lesion
Arteries and veins is bridged, and in the coronary artery after obtaining CABG, the processor 101 is also used to execute the coronary artery bypass grafting parameter really
Program is determined, to perform the steps of
With the scheme of the CABG of third bridging point, the coronary artery with stenotic lesion is bridged, after obtaining CABG
Coronary artery；Wherein, third puts up a bridge point including two, according to the direction of blood flow, is located at below stenotic lesion
On coronary artery on coronary artery and above stenotic lesion.
In an alternative embodiment, the scheme according to preset CABG, to coronal dynamic with stenotic lesion
Arteries and veins is bridged, and in the coronary artery after obtaining CABG, the processor 101 is also used to execute the coronary artery bypass grafting parameter really
Program is determined, to perform the steps of
With the scheme of third inlet point and the CABG of the 4th bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；Wherein, third inlet point is located on aorta ascendens, and the 4th puts up a bridge point according to blood flow
Direction be located on the coronary artery below stenotic lesion.
The embodiment of the present invention provides a kind of computer storage medium, and Figure 11 is that the computer in the embodiment of the present invention stores Jie
The structural schematic diagram of matter is stored with computer executable instructions in the computer storage medium 110, the meter as shown in figure 11
Calculation machine executable instruction is configured to execute the coronary artery bypass grafting determination method for parameter that other embodiments of the invention provide.
It should be understood by those skilled in the art that, the embodiment of the present invention can provide as method, system or computer program
Product.Therefore, the shape of hardware embodiment, software implementation or embodiment combining software and hardware aspects can be used in the present invention
Formula.Moreover, the present invention, which can be used, can use storage in the computer that one or more wherein includes computer usable program code
The form for the computer program product implemented on medium (including but not limited to magnetic disk storage and optical memory etc.).
The present invention be referring to according to the method for the embodiment of the present invention, the process of equipment (system) and computer program product
Figure and/or block diagram describe.It should be understood that every one stream in flowchart and/or the block diagram can be realized by computer program instructions
The combination of process and/or box in journey and/or box and flowchart and/or the block diagram.It can provide these computer programs
Instruct the processor of general purpose computer, special purpose computer, Embedded Processor or other programmable data processing devices to produce
A raw machine, so that being generated by the instruction that computer or the processor of other programmable data processing devices execute for real
The device for the function of being specified in present one or more flows of the flowchart and/or one or more blocks of the block diagram.
These computer program instructions, which may also be stored in, is able to guide computer or other programmable data processing devices with spy
Determine in the computer-readable memory that mode works, so that it includes referring to that instruction stored in the computer readable memory, which generates,
Enable the manufacture of device, the command device realize in one box of one or more flows of the flowchart and/or block diagram or
The function of being specified in multiple boxes.
These computer program instructions also can be loaded onto a computer or other programmable data processing device, so that counting
Series of operation steps are executed on calculation machine or other programmable devices to generate computer implemented processing, thus in computer or
The instruction executed on other programmable devices is provided for realizing in one or more flows of the flowchart and/or block diagram one
The step of function of being specified in a box or multiple boxes.
The foregoing is only a preferred embodiment of the present invention, is not intended to limit the scope of the present invention.
Claims (11)
1. a kind of coronary artery bypass grafting determination method for parameter characterized by comprising
According to the data of the coronary artery computed tomography radiography CTA got, it is reconstructed, obtains with stenotic lesion
Coronary artery, and determine outlet to be measured corresponding with the stenotic lesion；
The coronary artery with stenotic lesion is repaired, the coronary artery of no stenotic lesion is obtained；
The coronal of the no stenotic lesion is determined using preset hydrodynamics algorithm according to the impedance of the outlet to be measured
The blood flow total value of outlet to be measured described in artery；
According to the scheme of preset coronary artery bypass grafting CABG, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；
According to the impedance of the outlet to be measured, using the hydrodynamics algorithm, in the coronary artery after determining the CABG
The blood flow total value of the outlet to be measured；
The blood flow total value of the outlet to be measured according to the coronary artery after the CABG and the no stenotic lesion
The blood flow total value of outlet to be measured described in coronary artery, determines coronary artery bypass grafting parameter；
Wherein, the coronary artery bypass grafting parameter is for characterizing the health degree coronarius after the CABG.
2. the method according to claim 1, wherein described in the coronary artery according to after the CABG to
Measure the blood flow summation of outlet to be measured described in the blood flow total value of mouth and the coronary artery of the no stenotic lesion
Value, determines the coronary artery bypass grafting parameter of CABG, comprising:
Hat by the blood flow total value of outlet to be measured described in the coronary artery after the CABG, with the no stenotic lesion
Ratio between the blood flow total value of outlet to be measured described in shape artery, is determined as the coronary artery bypass grafting parameter.
3. the method according to claim 1, wherein according to the coronary artery computed tomography got
The data of radiography CTA, are reconstructed, and obtain the coronary artery with stenotic lesion, and determine opposite with the stenotic lesion
After the outlet to be measured answered, the method also includes:
According to the impedance of the outlet to be measured, using the hydrodynamics algorithm, determine described coronal with stenotic lesion
The blood flow total value of outlet to be measured described in artery；
The blood flow total value of the outlet to be measured according to the coronary artery with stenotic lesion and described without narrow
The blood flow total value of outlet to be measured described in the coronary artery of lesion determines described coronarius with stenotic lesion
State parameter；
Wherein, the state parameter is used to characterize the severe degree coronarius with stenotic lesion.
4. according to the method described in claim 3, it is characterized in that, in the coronary artery according to stenotic lesion
The blood stream of outlet to be measured described in the coronary artery of the blood flow total value of the outlet to be measured and the no stenotic lesion
Total value is measured, determines the state parameter coronarius with stenotic lesion, comprising:
By the blood flow total value of outlet to be measured described in the coronary artery with stenotic lesion, with described without narrow disease
Ratio between the blood flow total value of outlet to be measured described in the coronary artery of change determines the hat with stenotic lesion
The state parameter of shape artery.
5. the method according to claim 1, wherein described according to preset coronary artery bypass grafting CABG's
Scheme bridges the coronary artery with stenotic lesion, the coronary artery after obtaining CABG, comprising:
With the scheme of the first inlet point and the CABG of the first bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining the CABG；
Wherein, first inlet point is located in internal mammary artery, and described first puts up a bridge point according to the direction of blood flow, is located at institute
It states on the coronary artery below stenotic lesion.
6. the method according to claim 1, wherein the side according to preset Coronary artery bypass CABG
Case bridges the coronary artery with stenotic lesion, the coronary artery after obtaining CABG, comprising:
With the scheme of the second inlet point and the CABG of the second bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining the CABG；
Wherein, second inlet point is located in internal mammary artery, and described second puts up a bridge point including two, according to the side of blood flow
To, be located on the coronary artery below the stenotic lesion and the stenotic lesion above coronary artery on.
7. the method according to claim 1, wherein the side according to preset Coronary artery bypass CABG
Case bridges the coronary artery with stenotic lesion, the coronary artery after obtaining CABG, comprising:
With the scheme of the CABG of third bridging point, the coronary artery with stenotic lesion is bridged, is obtained described
Coronary artery after CABG；
Wherein, the third puts up a bridge point including two, according to the direction of blood flow, is located at below the stenotic lesion
On coronary artery on coronary artery and above the stenotic lesion.
8. the method according to claim 1, wherein the side according to preset Coronary artery bypass CABG
Case bridges the coronary artery with stenotic lesion, the coronary artery after obtaining CABG, comprising:
With the scheme of third inlet point and the CABG of the 4th bridging point, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining the CABG；
Wherein, the third inlet point is located on aorta ascendens, and the 4th bridging point distinguishes position according to the direction of blood flow
On coronary artery below the stenotic lesion.
9. a kind of determining device of coronary artery bypass grafting parameter characterized by comprising
Reconstructed module is reconstructed, obtains for the data according to the coronary artery computed tomography radiography CTA got
To the coronary artery with stenotic lesion, and determine outlet to be measured corresponding with the stenotic lesion；
Repair module obtains the coronal dynamic of no stenotic lesion for repairing to the coronary artery with stenotic lesion
Arteries and veins；
First determining module, using preset hydrodynamics algorithm, is determined described for the impedance according to the outlet to be measured
The blood flow total value of outlet to be measured described in coronary artery without stenotic lesion；
Bridge module, for the scheme according to preset coronary artery bypass grafting CABG, to the hat with stenotic lesion
Shape artery is bridged, the coronary artery after obtaining CABG；
Second determining module, using the hydrodynamics algorithm, is determined described for the impedance according to the outlet to be measured
The blood flow total value of outlet to be measured described in coronary artery after CABG；
Third determining module, for the outlet to be measured according to the coronary artery after the CABG blood flow total value and
The blood flow total value of outlet to be measured described in the coronary artery of the no stenotic lesion, determines coronary artery bypass grafting parameter；
Wherein, the coronary artery bypass grafting parameter is for characterizing the health degree coronarius after the CABG.
10. a kind of electronic equipment, which is characterized in that the electronic equipment includes processor, memory and communication bus；
The communication bus is for realizing the connection communication between processor and memory；
The processor is used to execute the determination program that coronary artery bypass grafting parameter is stored in memory, to perform the steps of
According to the data of the coronary artery computed tomography radiography CTA got, it is reconstructed, obtains with stenotic lesion
Coronary artery, and determine outlet to be measured corresponding with the stenotic lesion；
The coronary artery with stenotic lesion is repaired, the coronary artery of no stenotic lesion is obtained；
The coronal of the no stenotic lesion is determined using preset hydrodynamics algorithm according to the impedance of the outlet to be measured
The blood flow total value of outlet to be measured described in artery；
According to the scheme of preset coronary artery bypass grafting CABG, bridge is carried out to the coronary artery with stenotic lesion
It connects, the coronary artery after obtaining CABG；
According to the impedance of the outlet to be measured, using the hydrodynamics algorithm, in the coronary artery after determining the CABG
The blood flow total value of the outlet to be measured；
The blood flow total value of the outlet to be measured according to the coronary artery after the CABG and the no stenotic lesion
The blood flow total value of outlet to be measured described in coronary artery, determines coronary artery bypass grafting parameter；
Wherein, the coronary artery bypass grafting parameter is for characterizing the health degree coronarius after the CABG.
11. a kind of computer storage medium, which is characterized in that be stored with the executable finger of computer in the computer storage medium
It enables, which is configured to execute the determination for the coronary artery bypass grafting parameter that any one of the claims 1 to 8 provide
Method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811614134.7A CN109700475B (en) | 2018-12-27 | 2018-12-27 | Method, device, equipment and storage medium for determining coronary bypass parameters |
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