CN109682958A - A kind of acceleration transducer signals compensation method for thrombelastogram instrument - Google Patents
A kind of acceleration transducer signals compensation method for thrombelastogram instrument Download PDFInfo
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Abstract
The present invention proposes a kind of acceleration transducer signals compensation method for thrombelastogram instrument, and the interference of sampling noise signal is eliminated using N point mean filter；Piezoelectric transducer technology is used simultaneously, analyzes vibration signal mathematical model, is eliminated due to vibrating bring vibration noise, is retained effective dynamic signal；Since the frequency and amplitude of vibration have periodicity and randomness, it is superimposed with useful signal, it cannot be achieved the effect that under special circumstances by Digital Signal Processing completely, therefore there is the case where strong correlation in piezoelectric transducer feedback signal and vibration noise, it is inputted by the feedback signal of piezoelectric transducer, better filter effect can be reached to compensate dynamic signal.
Description
Technical field
The present invention relates to field of signal processing, especially a kind of acceleration transducer signals for thrombelastogram instrument are mended
Compensation method.
Background technique
Thrombelastogram is to acquire blood in the power being solidified in fibrinolytic engineering by kinetic sensors detection technique
Variable signal is learned, parametric results are calculated by data processing, the Coagulability for patient is assessed, and is applied to LVD blood and is examined
The coagulation analysis in survey field, Coagulability assessment is usually used in clinical evaluation, such as postoperative hemorrhage, heart outer operation or postoperative blood
In bolt, organ transplant, wound and cardiac surgical procedure or the thrombosis of postoperative generation.
United States blood company's T EG elastic force figure instrument can monitor the blood coagulation situation of patient at present, be based primarily upon following two thing
Real: (1) final result of Blood Coagulation Process is to form blood clot；(2) physical property (rate, hardness, the stabilization of blood clot
Property) will determine whether patient has normal coagulation function, if it can bleeding or formation thrombus.Teg Data Analysis Software is to adopting
The dynamic signal of sample is filtered identification, data screening, output parameter result.
However, the above method but has the following problems: (1) Teg Data Analysis Software is carried out to by dynamic signal
Single simple filtering often introduces mechanical oscillation in instrumentation engineering, what the noise signal that mechanical oscillation generate changed
Frequency, filter can not eliminate noise signal at all；(2) data screening algorithm can only eliminate small vibration signal to a certain extent
Interference, and at blood coagulation initial stage, the screening effect to the fast-changing signal of blood coagulation is not apparent.
Summary of the invention
To solve the above-mentioned problems, the present invention proposes that a kind of acceleration transducer signals for thrombelastogram instrument compensate
Method eliminates the interference of sampling noise signal and due to vibrating bring vibration noise, and the feedback letter for passing through piezoelectric transducer
Number input, to compensate dynamic signal to reach better filter effect.
What the invention is realized by the following technical scheme:
The present invention proposes a kind of acceleration transducer signals compensation method for thrombelastogram instrument, including following step
It is rapid:
(1) dynamics digital signal S1 is obtained using dynamic signal sampling；
(2) dynamics digital signal S1 is subjected to mean filter, obtains digital signal S2；
(3) vibration is sampled into three directions (X-axis, Y-axis, Z axis) vibration digital signal A1-1, A1-2, A1-3；
(4) three direction vibration number word signal A1-1, A1-2, A1-3 become three direction digital signals by autocorrelation filter
A2-1,A2-2,A2-3；
(5) digital signal S2 include effective dynamic signal S and vibration interference signal N, by three direction digital signal A2-1,
A2-2, A2-3 calculate vibration interference signal N by formula Gaussian normal coefficient gass (n) conversion, then in digital signal S2
In filter out vibration interference signal N, extracted effective power signal S, output digit signals S3；
(6) digital signal S3 recognizes the stable maximum point and minimum point of effective impulse by algorithm of climbing；
(7) all maximum points are combined, generates elastic force figure coenvelope line, all minimum points are combined, generate elastic force
Figure lower envelope line obtains elastic force figure G1；
(8) elastic force figure G1 is calculated, corresponding parametric results can be exported.
Preferably, in step (1), inducing probes immerse in blood, and the strength transfer of blood clotting and fibrinolytic is to induction
Probe is transformed into analog electrical signal, after signal amplifier amplifies, is sampled into dynamics digital signal S1 by processor AD.
Preferably, in step (2), N point mean filter is carried out to dynamics digital signal S1 and eliminates sampling noise, together
When remain the details of dynamic signal in dynamics digital signal S1, digital signal S2 is obtained after filtering.
Preferably, in step (4), auto-correlation function used in autocorrelation filter are as follows:
Preferably, in step (5), the current value of the current value of vibration interference signal N and A2, past value, future value are all
There is strong correlation, can just indicate this relationship using Gaussian normal coefficient gass (n), and N value is three direction digital signals power
And, weight q1, q2, q3 are variations again, and the weighting function of A2 and N value is q=a*x3+b*x2+c*x+d。
Beneficial effects of the present invention:
Acceleration transducer signals compensation method for thrombelastogram instrument of the invention is eliminated using N point mean filter
Sample the interference of noise signal；Piezoelectric transducer technology is used simultaneously, analyzes vibration signal mathematical model, is eliminated due to vibrating band
The vibration noise come, retains effective dynamic signal；Since the frequency and amplitude of vibration have periodicity and randomness, and have
It imitates Signal averaging together, cannot be achieved the effect that under special circumstances by Digital Signal Processing completely, therefore
Piezoelectric transducer feedback signal and vibration noise have the case where strong correlation, are inputted, are come by the feedback signal of piezoelectric transducer
Compensation dynamic signal can reach better filter effect.
Detailed description of the invention
Fig. 1 is that the step process of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention is illustrated
Figure；
Fig. 2 is that the dynamics number of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention is believed
Number curve graph；
Fig. 3 is the filtered power of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention
Learn digital signal curve graph；
Fig. 4 is the filtered vibration of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention
Waveform diagram of the signal in X-direction；
Fig. 5 is the filtered vibration of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention
The waveform diagram of signal in the Y direction；
Fig. 6 is the filtered vibration of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention
Waveform diagram of the signal in Z-direction；
Fig. 7 is the elastic force envelope of the acceleration transducer signals compensation method for thrombelastogram instrument of the invention.
Specific embodiment
In order to it is clearer, completely illustrate technical solution of the present invention, the present invention is made with reference to the accompanying drawing further
Explanation.
Referring to FIG. 1, the present invention proposes a kind of acceleration transducer signals compensation method for thrombelastogram instrument, packet
Include following steps:
(1) dynamics digital signal S1 is obtained using dynamic signal sampling；
(2) dynamics digital signal S1 is subjected to mean filter, obtains digital signal S2；
(3) vibration is sampled into three directions (X-axis, Y-axis, Z axis) vibration digital signal A1-1, A1-2, A1-3；
(4) three direction vibration number word signal A1-1, A1-2, A1-3 become three direction digital signals by autocorrelation filter
A2-1,A2-2,A2-3；
(5) digital signal S2 include effective dynamic signal S and vibration interference signal N, by three direction digital signal A2-1,
A2-2, A2-3 calculate vibration interference signal N by formula Gaussian normal coefficient gass (n) conversion, then in digital signal S2
In filter out vibration interference signal N, extracted effective power signal S, output digit signals S3；
(6) digital signal S3 recognizes the stable maximum point and minimum point of effective impulse by algorithm of climbing；
(7) all maximum points are combined, generates elastic force figure coenvelope line, all minimum points are combined, generate elastic force
Figure lower envelope line obtains elastic force figure G1；
(8) elastic force figure G1 is calculated, corresponding parametric results can be exported.
Preferably, in step (1), inducing probes immerse in blood, and the strength transfer of blood clotting and fibrinolytic is to induction
Probe is transformed into analog electrical signal, after signal amplifier amplifies, is sampled into dynamics digital signal S1 by processor AD, such as schemes
Shown in 2.
Preferably, in step (2), N point mean filter is carried out to dynamics digital signal S1 and eliminates sampling noise, together
When remain the details of dynamic signal in dynamics digital signal S1, digital signal S2 is obtained after filtering, as shown in Figure 3.
In the present embodiment, wherein the value of N is selected according to AD sample frequency, mean filter using it is distinctive from
Weighting algorithm is adapted to, with the thought of fuzzy mathematics, filter weights are optimized, not only inhibits noise but also is effectively maintained
The details of dynamic signal observes digital signal S2, and compared to original digital signal S1, noise spot is eliminated.
In the present embodiment, vibration is changed journey analog electrical signal by piezoelectric transducer module, after hardware circuit amplifies,
Three directions (X-axis, Y-axis, Z axis) vibration digital signal A1-1, A1-2, A1-3 are sampled by processor.
Preferably, in step (4), vibration digital signal A1 is often mingled with some random noises, and demand makes an uproar these
Sound could use after filtering out, and auto-correlation algorithm can identify the vibration signal for identifying in random noise and having filtering, and the present invention uses
Auto-correlation algorithm eliminates the random noise in A1, and the amplitude and frequency of signal also remain unchanged, three are obtained after auto-correlation computation
Direction digital signal A2-1, A2-2, A2-3；Auto-correlation function used in autocorrelation filter are as follows:
Since most of random noise is=0 or so, when tending to infinity, random noise is equal to zero, etc.
In A2, as shown in Fig. 4, Fig. 5, Fig. 6.
Preferably, in step (5), since digital signal S2 includes effective dynamic signal S and vibration interference signal N,
It needs N and A2-1, A2-2, A2-3 to set up to contact and could filter out vibration interference signal N in digital signal S2, retain effective
Dynamic signal S, and the current value of vibration interference signal N and the current value of A2, past value, future value have strong correlation, utilize
Gaussian normal coefficient gass (n) can just indicate this relationship, and N value be three direction digital signal weights and, weight q1,
Q2, q3 are variations, and the weighting function of A2 and N value is q=a*x3+b*x2+c*x+d。
N1 (t)=gass (0) * A2-1 (t-k) ...+gass (k) * A2-1 (t) ...+gass (2k) * A2-1 (t+k)；
N2 (t)=gass (0) * A2-2 (t-k) ...+gass (k) * A2-2 (t) ...+gass (2k) * A2-2 (t+k)；
N3 (t)=gass (0) * A2-3 (t-k) ...+gass (k) * A2-3 (t) ...+gass (2k) * A2-3 (t+k)；
N (t)=q1 (t) * N1 (t)+q2 (t) * N2 (t)+q3 (t) * N3 (t).
N is calculated by formula conversion by three direction digital signal A2-1, A2-2, A2-3 above, digital signal S2 is risen
Good compensation effect has been arrived, effective power signal S has been extracted, output digit signals S3 reaches the access of pulse recognition
Condition.
In the present embodiment, the stable maximum point and minimum point of effective impulse is recognized by algorithm of climbing；
All maximum points are combined, elastic force figure coenvelope line is generated, all minimum points are combined, generate elastic force figure lower envelope line,
Elastic force figure G1 is obtained, as shown in Figure 7.
In the present embodiment, certain formula calculating is carried out to elastic force figure G1, all parametric results can be calculated, it can
To find out, after the signal compensation of piezoelectric transducer, the anti-vibration interference of parameter is stronger.
Acceleration transducer signals compensation method for thrombelastogram instrument of the invention is eliminated using N point mean filter
Sample the interference of noise signal；Piezoelectric transducer technology is used simultaneously, analyzes vibration signal mathematical model, is eliminated due to vibrating band
The vibration noise come, retains effective dynamic signal；Since the frequency and amplitude of vibration have periodicity and randomness, and have
It imitates Signal averaging together, cannot be achieved the effect that under special circumstances by Digital Signal Processing completely, therefore
Piezoelectric transducer feedback signal and vibration noise have the case where strong correlation, are inputted, are come by the feedback signal of piezoelectric transducer
Compensation dynamic signal can reach better filter effect.
Certainly, the present invention can also have other numerous embodiments, be based on present embodiment, those skilled in the art
Obtained other embodiments under the premise of not making any creative work belong to the range that the present invention is protected.
Claims (5)
1. a kind of acceleration transducer signals compensation method for thrombelastogram instrument, which comprises the following steps:
(1) dynamics digital signal S1 is obtained using dynamic signal sampling；
(2) dynamics digital signal S1 is subjected to mean filter, obtains digital signal S2；
(3) vibration is sampled into three directions (X-axis, Y-axis, Z axis) vibration digital signal A1-1, A1-2, A1-3；
(4) three direction vibration number word signal A1-1, A1-2, A1-3 by autocorrelation filter become three direction digital signal A2-1,
A2-2,A2-3；
(5) digital signal S2 includes effective dynamic signal S and vibration interference signal N, by three direction digital signals A2-1, A2-
2, A2-3 calculates vibration interference signal N by formula Gaussian normal coefficient gass (n) conversion, then filters in digital signal S2
Except vibration interference signal N, effective power signal S, output digit signals S3 have been extracted；
(6) digital signal S3 recognizes the stable maximum point and minimum point of effective impulse by algorithm of climbing；
(7) all maximum points are combined, generates elastic force figure coenvelope line, all minimum points are combined, generated under elastic force figure
Envelope obtains elastic force figure G1；
(8) elastic force figure G1 is calculated, corresponding parametric results can be exported.
2. the acceleration transducer signals compensation method according to claim 1 for thrombelastogram instrument, feature exist
In in step (1), inducing probes immerse in blood, and the strength transfer of blood clotting and fibrinolytic is transformed into mould to inducing probes
Quasi- electric signal is sampled into dynamics digital signal S1 by processor AD after signal amplifier amplifies.
3. the acceleration transducer signals compensation method of thrombelastogram according to claim 1, which is characterized in that in step
Suddenly in (2), N point mean filter is carried out to dynamics digital signal S1 and eliminates sampling noise, while remaining dynamics number
The details of dynamic signal in signal S1, obtains digital signal S2 after filtering.
4. the acceleration transducer signals compensation method according to claim 1 for thrombelastogram instrument, feature exist
In, in step (4), auto-correlation function used in autocorrelation filter are as follows:
5. the acceleration transducer signals compensation method according to claim 1 for thrombelastogram instrument, feature exist
In in step (5), the current value and the current value of A2, past value, future value of vibration interference signal N has strong correlation, utilizes
Gaussian normal coefficient gass (n) can just indicate this relationship, and N value be three direction digital signal weights and, weight q1,
Q2, q3 are variations, and the weighting function of A2 and N value is q=a*x3+b*x2+c*x+d。
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