CN109666583A - Bioreactor with culture jar platform for placing - Google Patents
Bioreactor with culture jar platform for placing Download PDFInfo
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- CN109666583A CN109666583A CN201811359575.7A CN201811359575A CN109666583A CN 109666583 A CN109666583 A CN 109666583A CN 201811359575 A CN201811359575 A CN 201811359575A CN 109666583 A CN109666583 A CN 109666583A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/52—Mobile; Means for transporting the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
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Abstract
The invention discloses a kind of bioreactors with culture jar platform for placing, comprising: reaction kettle tank and host；Reaction kettle tank is detachably installed to host；Reaction kettle tank includes: tank body, for accommodating culture solution；And agitating paddle, it is used for stir culture liquid；Host includes: body；Peristaltic pump, for being reaction kettle tank feed flow；Controller, for controlling peristaltic pump；And stirring motor, for driving agitating paddle to rotate；Peristaltic pump, controller and stirring motor are installed to body；Tank body is detachably installed to body；Body is formed with the culture jar platform for placing that can put culture jar；Culture jar platform for placing is set to the lower section of peristaltic pump.The setting of bioreactor with culture jar platform for placing, culture jar platform for placing position helps to be convenient for changing culture jar, reduces the power demand to peristaltic pump.
Description
Technical field
The present invention relates to a kind of bioreactors with culture jar platform for placing.
Background technique
Pei Yang Ye bottle for accommodating culture solution is generally positioned at the top of the body of bioreactor, it has not been convenient to change drain
When pipe or replacement culture jar, since the height of culture jar is higher, peristaltic pump can provide higher power.
Summary of the invention
To solve the deficiencies in the prior art, the present invention provides a kind of biological respinses with culture jar platform for placing
Device, culture solution screen position is reasonable, is convenient for changing, smaller to the power demand of peristaltic pump.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of bioreactor with culture jar platform for placing, comprising: reaction kettle tank and host；Reaction kettle tank is removable
Installation is unloaded to host；Reaction kettle tank includes: tank body, for accommodating culture solution；And agitating paddle, it is used for stir culture liquid；Host packet
It includes: body；Peristaltic pump, for being reaction kettle tank feed flow；Controller, for controlling peristaltic pump；And stirring motor, it is stirred for driving
Mix paddle rotation；Peristaltic pump, controller and stirring motor are installed to body；Tank body is detachably installed to body；Body is formed with energy
Enough put the culture jar platform for placing of culture jar；Culture jar platform for placing is set to the lower section of peristaltic pump.
Further, the bioreactor with culture jar platform for placing, further includes: fixed device is deposited for fixation
Contain the culture jar of culture solution；Fixed device is detachably set to culture jar platform for placing.
Further, fixed device includes: retaining clip and movable clamp；Movable clamp is articulated to retaining clip；
The fixing groove of multiple culture jars for having culture solution for fixed storage is collectively formed in movable clamp and retaining clip.
Further, movable clamp is formed with metal pin；Retaining clip is formed with mounting groove；Metal pin can pacify
Sliding is in tankage to adjust position of the movable clamp relative to retaining clip；The side wall of mounting groove is fixed with for attracting metallic pin
The magnet of column；Magnet attracts position of the metal pin to fixed movable clamp relative to retaining clip.
Further, fixed device further include: compress pin and holddown spring；It compresses pin and is slidingly attached to movable clamp；Pressure
Tight spring makes compression pin compress culture jar to pin application active force is compressed.
Further, agitating paddle is connected with the first connection structure；Stirring motor be connected with for the first connection structure pair
The second connection structure connect；When tank body is connect with body, the first connection structure and the docking of the second connection structure are so that stirring motor
Drive agitating paddle rotation.
Further, one in the first connection structure and the second connection structure is convex block；First connection structure and second
Another in connection structure is the groove that can be inserted into for convex block；When the first connection structure and the second connection structure are docked,
Convex block is inserted into groove so that the first connection structure and the second connection structure can rotate synchronously.
Further, host further include: touch control operation display screen；Touch control operation display screen is installed to body；
Touch control operation display location is in the top of culture jar platform for placing.
Further, host further include: oxygen sensor, for detecting the oxygen in reaction kettle tank；Temperature sensor is used
Temperature in detection reaction kettle tank；With pH sensor, for detecting the pH value in reaction kettle tank；Oxygen sensor, temperature pass
Sensor and pH sensor are detachably connected to tank body.
Further, host further include: air filter, for being filtered to the gas being input in reaction kettle tank；
And gas-guide tube, for the filtered gas of air filter to be directed into reaction kettle tank；Gas-guide tube is detachably connected to tank body.
The invention has the beneficial effects that the bioreactor with culture jar platform for placing provided, culture solution screen position
It sets rationally, is convenient for changing, it is smaller to the power demand of peristaltic pump.
Culture jar can be fixed to the display platform of body by the retaining clip of fixed device and movable clamp cooperation, thus
Culture jar is avoided to be overturned.The compression pin that fixed device has can carry out Pei Yang Ye bottle to compress to guarantee fixed reliable
Property.Culture jar platform for placing can be fixed on for different size of culture jar by compressing pin and holddown spring cooperation.
Detailed description of the invention
Fig. 1 is a kind of perspective view of bioreactor of the invention；
Fig. 2 is the perspective view at another visual angle of the bioreactor in Fig. 1；
Fig. 3 is the top view of the bioreactor in Fig. 1；
Fig. 4 is the front view of the bioreactor in Fig. 1；
Fig. 5 is the signal that the first Rack Body, the second Rack Body and reaction kettle tank of the bioreactor in Fig. 4 are separated from each other
Figure；
Fig. 6 is the schematic diagram of the part-structure of the bioreactor in Fig. 1；
Fig. 7 is the schematic diagram at another visual angle of the structure in Fig. 6；
Fig. 8 is the agitating paddle of the bioreactor in Fig. 1, the first connection structure, the second connection structure and stirring motor
Schematic diagram；
Fig. 9 is the schematic diagram that the bioreactor in Fig. 1 is equipped with fixed device；
Figure 10 is the schematic diagram of the fixation device of the bioreactor in Fig. 9；
Figure 11 is the cross-sectional view of the retaining clip of the fixation device in Figure 10；
Figure 12 is the cross-sectional view of the movable clamp of the fixation device in Figure 10；
Figure 13 is the cross-sectional view of the fixation device in Figure 10.
Bioreactor 100, reaction kettle tank 10, tank body 11, agitating paddle 12, the first connection structure 13, the first center line
13a, host 20, body 21, the first Rack Body 21a, the first electric connection terminal 211a, the second Rack Body 21b, the second electric connecting terminal
Sub- 211b, peristaltic pump 22, controller 23, stirring motor 24, electric machine support 24a, touch control operation display screen 25, air filter
26, the second connection structure 27, the second center line 27a drives muscle 271, culture jar platform for placing 28, and fixed device 29 is fixed
Clamp 291, mounting groove 292, movable clamp 293, metal pin 294, fixing groove 295, magnet 296 compress pin 297, compress bullet
Spring 298, level detection sensors device 30, culture jar 200.
Specific embodiment
Specific introduce is made to the present invention below in conjunction with the drawings and specific embodiments.
As shown in figure 1 to figure 13, a kind of bioreactor 100, comprising: reaction kettle tank 10 and host 20.Reaction kettle tank 10
It is detachable to install to host 20.Reaction kettle tank 10 includes: tank body 11 and agitating paddle 12.Tank body 11 is for accommodating culture solution.Into
Culture solution can be delivered in tank body 11 when row culture and carry out biological culture.Agitating paddle 12 is used for stir culture liquid.Agitating paddle 12
Culture solution in tank body 11 is stirred, avoids precipitating, so that culture solution is come into full contact with so as to sufficiently react.
Host 20 includes: body 21, peristaltic pump 22, controller 23 and stirring motor 24.Peristaltic pump 22 is used to be reaction kettle
10 feed flow of tank.It is reacted specifically, culture solution is delivered in tank body 11 by peristaltic pump 22.Controller 23 is wriggled for controlling
Pump 22.Controller 23 instructs control peristaltic pump 22 to convey culture solution according to the input of user.Stirring motor 24 is for driving stirring
Paddle 12 rotates.Specifically, agitating paddle 12 is stirred the culture solution in tank body 11 under the driving of stirring motor 24.Host
20 further include electric machine support 24a.Stirring motor 24 is fixed to electric machine support 24a.
As a kind of specific embodiment, peristaltic pump 22, controller 23 and the installation of stirring motor 24 to body 21.Tank body
11 detachably install to body 21.Agitating paddle 12 is connected with the first connection structure 13.Stirring motor 24 is connected with for first
The second connection structure 27 that connection structure 13 is docked.When tank body 11 is connect with body 21, the first connection structure 13 and the second connection
Structure 27 is docked so that stirring motor 24 drives agitating paddle 12 to rotate.
Specifically, by the first connection structure 13 of agitating paddle 12 and the second connection structure 27 of stirring motor 24 docking peace
Tank body 11 can be installed on body 21 by dress, to carry out culture solution culture.First connection structure 13 and the second connection structure 27
It may be constructed inserting connection.When needing replacing the tank body 11 for another different model to be suitable for the culture solution culture of another scale of construction
When, the first connection structure 13 and the separation of the second connection structure 27 can be removed into tank body 11 to replace the tank of another different model
Body 11.Wherein, the culture solution of another scale of construction refers to different for the culture solution of reaction and the volume of the culture solution.A variety of different rule
Lattice or the reaction kettle tank 10 of model can be installed to host 20.
As a preferred embodiment, one in the first connection structure and the second connection structure is convex block.First
Another in connection structure and the second connection structure is the groove that can be inserted into for convex block.In the first connection structure 13 and second
When connection structure 27 is docked, convex block is inserted into groove so that the first connection structure 13 synchronous can turn with the second connection structure 27
It is dynamic.
Specifically, the first connection structure 13 is groove.Second connection structure 27 is convex block.As a kind of optional implementation
Mode, the first connection structure are convex block.Second connection structure is groove.
Tank body 11 is installed on by body 21 using the grafting mounting structure of convex block and groove, structure is simple, high reliablity, and
It can guarantee that the first connection structure 13 and the second connection structure 27 rotate synchronously, realize that stirring motor 24 drives agitating paddle 12 to rotate
To be stirred to culture solution.
As a preferred embodiment, the definition of the first connection structure 13 has the first center line 13a.Second connection structure
27 definition have the second center line 27a.First connection structure 13 includes several driver slots.Several driver slots are in the first center line
It is uniformly distributed in the circumferential direction of 13a.Second connection structure 27 is equipped with multiple driving muscle 271.Multiple driving muscle 271 are in the second center line
It is uniformly distributed in the circumferential direction of 27a.When first connection structure 13 and the second connection structure 27 are docked, the first center line 13a and second
Center line 27a is overlapped, and driver slot is inserted into driving muscle 271.
Specifically, driver slot is inserted into driving muscle 271 so that by the installation of tank body 11 to body 21, structure is simple, and installation is just
It is prompt.Stirring motor 24 drives driving muscle 271 to rotate around the second center line 27a in rotation.Drive muscle 271 by matching with driver slot
Crossed belt moves driver slot and rotates around the first center line 13a, that is, drives the rotation of the first connection structure 13 to drive agitating paddle 12 to rotate
Realize stirring.
As a kind of specific embodiment, shaft coupling connects the motor shaft and the second connection structure 27 of stirring motor 24.
Specifically, shaft coupling is directly connected to the motor shaft and the second connection structure 27 of stirring motor 24.Agitating paddle 12 is fixed to first
Connection structure 13.
As a preferred embodiment, the number of driving muscle 271 is greater than the number of driver slot.Specifically, will drive
The number of dynamic muscle 271 is set greater than the number of driver slot, convenient for muscle 271 will be driven to be inserted into driver slot.
As a preferred embodiment, the first connection structure 13 is interior flower pattern groove.Second connection structure 27 is ten
Font convex block.
Specifically, tank body 11 to be installed on to the side of body 21 using flower pattern groove in being inserted into cross convex block
Formula, it is simple and fast, it is easily installed.
As a preferred embodiment, the notch of the top of cross convex block and interior flower pattern groove be equipped with convenient for pair
The rounded structure or oblique angle structure connect.
Specifically, rounded structure or oblique angle structure, which can be oriented to cross convex block, is inserted into interior flower pattern groove, so that installation
It is more convenient.
As a preferred embodiment, host 20 further include: touch control operation display screen 25.Touch control operation display screen 25
Installation is to body 21, so that user inputs operation instruction or show the relevant information about bioreactor 100.
As a preferred embodiment, host 20 further include: oxygen sensor, temperature sensor and pH sensor.
Oxygen sensor is used to detect the oxygen in reaction kettle tank 10, and the oxygen information that will test is sent to touch control operation display screen
25.Temperature sensor is used to detect the temperature in reaction kettle tank 10, and the temperature information that will test is sent to touch control operation and shows
Display screen 25.PH sensor is used to detect the pH value in reaction kettle tank 10, and the pH value information that will test is sent to touch control operation
Display screen 25.
As a kind of specific embodiment, oxygen sensor, temperature sensor and pH sensor are detachably connected to
Tank body 11 can be disassembled installation to new tank body 11 and continue to detect when in order to replace tank body 11.
As a preferred embodiment, host 20 further include: air filter 26 and gas-guide tube.Air filter 26
For being filtered to the gas being input in reaction kettle tank 10, the substance of the obstruction reaction in gas is avoided to enter reaction kettle tank
Reaction rate is influenced in 10.It is for air guide tube to be directed into reaction kettle tank 10 in by the filtered gas of air filter 26.
As a kind of specific embodiment, gas-guide tube is detachably connected to tank body 11, will when in order to changing tank body 11
Gas-guide tube disassembles installation to new tank body 11, continues the filtered gas of air filter 26 being directed into new reaction
In kettle tank 10.
As a preferred embodiment, host 20 further include: catheter.Peristaltic pump 22 is led liquid by catheter
Enter to reaction kettle tank 10.As a kind of specific embodiment, catheter is detachably connected to tank body 11, in order to changing tank
Catheter is disassembled into installation to new tank body 11 when body 11, continues for the filtered liquid of air filter 26 to be directed into
In new reaction kettle tank 10.
Body 21 includes: the first Rack Body 21a and the second Rack Body 21b.Peristaltic pump 22 and controller 23 are installed to first
Rack Body 21a.Stirring motor 24 is installed to the second Rack Body 21b.Tank body 11 is detachably installed to the second Rack Body 21b.Second
Rack Body 21b is detachably installed to the first Rack Body 21a.Therefore, bioreactor 100 can be referred to as to have culture jar again
The bioreactor 100 of platform for placing.Specifically, detachably install can be to the first Rack Body 21a by the second Rack Body 21b
When transporting biological reactor 100, the second Rack Body 21b is disassembled from the first Rack Body 21a.It is convenient for biological respinse in this way
The transport of device 100.
The bottom of first Rack Body 21a and the second Rack Body 21b are equipped with support wheel.User can push the second Rack Body
21b moves the assembling for realizing the first Rack Body 21a and the second Rack Body 21b relative to the first Rack Body 21a.
As a preferred embodiment, the first Rack Body 21a is equipped with: the first electric connection terminal 211a.Second rack
Body 21b is equipped with: the second electric connection terminal 211b.Second electric connection terminal 211b is electrically connected to stirring motor 24.First electrical connection
Terminal 211a is electrically connected to the power supply powered for stirring motor 24.Second Rack Body 21b is connect with the first Rack Body 21a
When, the first electric connection terminal 211a is electrically connected to enable power supply for stirring electricity with the second electric connection terminal 211b composition
Machine 24 is powered.
Specifically, the first electric connection terminal 211a is arranged in the first Rack Body 21a, in the second Rack Body 21b setting the
Two electric connection terminal 211b, when the second Rack Body 21b is connect with the first Rack Body 21a, the first electric connection terminal 211a and
Two electric connection terminal 211b constitute electrical connection to enable power supply for the power supply of stirring motor 24.Setting is avoided in machine in this way
A plurality of cable electrical connection power supply and stirring motor 24 are set outside body 21, to avoid being located at the cable outside body 21
Line loss badly causes installation problems.Meanwhile it being connect by the second Rack Body 21b with the first Rack Body 21a and can realize that first is electrically connected
The electric connection of connecting terminal 211a and the second electric connection terminal 211b, structure is simple, easy for installation.
As a preferred embodiment, the second electric connection terminal 211b inserting relative to the first electric connection terminal 211a
Pull out installation direction of the direction perpendicular to tank body 11 relative to the second Rack Body 21b.
As a preferred embodiment, tank body 11 relative to the second Rack Body 21b installation direction perpendicular to second
Installation direction of the Rack Body 21b relative to the first Rack Body 21a.
As a preferred embodiment, the second Rack Body 21b is vertical relative to the installation direction of the first Rack Body 21a
In the pivot center of agitating paddle 12.
As a preferred embodiment, touch control operation display screen 25 is installed to the first Rack Body 21a.As a kind of excellent
The embodiment of choosing, detachably installation carries out more air filter 26 to the first Rack Body 21a air filter 26
It changes.
As a preferred embodiment, the second Rack Body 21b is formed far from one end of the first Rack Body 21a to separate
The arcuate structure of the side protrusion of first Rack Body 21a.
As a preferred embodiment, the upper surface of one end far from the first Rack Body 21a of the second Rack Body 21b
It constitutes semicircle.
Specifically, setting semicircle for the upper surface of one end far from the first Rack Body 21a of the second Rack Body 21b
Shape, second Rack Body 21b will not generate interference to user when convenient for the user to operate.
The body of above-mentioned bioreactor 100 is formed with the culture jar platform for placing 28 that can put culture jar 200.
When supplying culture solution into tank body, culture jar 200 can be placed in culture jar platform for placing 28.So biological respinse
Device 100 can be referred to as the bioreactor with culture jar platform for placing again.Specifically, platform for placing is set to wriggling
The lower section of pump helps to shorten feed flow path, reduces the requirement to wriggling pump power.
As a preferred embodiment, the bioreactor with culture jar platform for placing further includes fixed device
29.Fixed device 29 can be used for the culture jar 200 for being stored with culture solution being fixed to culture jar platform for placing 28.Fixed dress
It sets 29 and is detachably set to culture jar platform for placing 28.
Specifically, culture jar 200, which passes through fixed device 29 and is mounted on culture jar platform for placing 28 and can keep away, overturns training
The case where nutrient solution bottle 200, occurs.And fixed device 29 is set to culture jar platform for placing 28 detachably convenient for being dismantled down
To be cleaned.
As a preferred embodiment, fixed device 29 includes: retaining clip 291 and movable clamp 293.Activity folder
Body 293 is articulated to retaining clip 291.Movable clamp 293 and retaining clip 291 are collectively formed multiple to be had for fixed storage
The fixing groove 295 of the culture jar 200 of culture solution.
Furtherly, Pei Yang Ye bottle is placed in mounting groove 292, and by retaining clip 291 and movable clamp 293 from
Culture jar 200 is fixed in mounting groove 292 by the mode of the sandwich Pei Yang Ye bottle of culture jar 200.
As a preferred embodiment, movable clamp 293 is formed with metal pin 294.Retaining clip 291 is formed with
Mounting groove 292.Metal pin 294 can be slided in mounting groove 292 to adjust movable clamp 293 relative to retaining clip 291
Position.The side wall of mounting groove 292 is fixed with the magnet 296 for attracting metal pin 294.Magnet 296 attracts metal pin
294 position to fixed movable clamp 293 relative to retaining clip 291.
Specifically, first culture jar 200 is placed in fixing groove 295 in fixed culture jar 200, then will
Metal pin 294 is inserted into mounting groove 292 until the cell wall of fixing groove 295 surrounds and contacts the two sides of culture jar 200 to clamp
Pei Yang Ye bottle.The position of metal pin 294 is to fix position at this time for definition.Magnet 296 positioned at 292 side wall of mounting groove attracts gold
Belong to pin 294 to which metal pin 294 is fixed on fixed position.
As a preferred embodiment, fixed device 29 further include: compress pin 297 and holddown spring 298.Compress pin
297 are slidingly attached to movable clamp 293.298 pairs of compression pins 297 of holddown spring, which apply active force, to be made to compress the compression culture of pin 297
Liquid bottle 200.
It further says, when the feeding liquid bottle of training is smaller, 298 pairs of compression pins 297 of holddown spring apply active forces so as to compress
Pin 297 compresses culture jar 200.At this point, the cell wall for compressing pin 297 and fixing groove 295 clamps culture from 200 two sides of culture jar
Liquid bottle 200 is with fixed by culture jar 200.Fixed device 29 is made to be capable of fixing different size of culture in this way
Liquid bottle 200.
Touch control operation display location is in the top of culture jar platform for placing 28.
As a preferred embodiment, the cell wall of fixing groove 295 is equipped with level detection sensors device 30.Level detection passes
Sensor 30 can detect the liquid level position of culture solution in culture jar.When level detection sensors device 30 detects liquid level position
When lower than predeterminated position, liquid level position information is sent to controller 23.Touch control operation display screen 25 shows liquid level position information,
And user is prompted to replace culture jar.
The basic principles, main features and advantages of the invention have been shown and described above.The technical staff of the industry should
Understand, the above embodiments do not limit the invention in any form, all obtained by the way of equivalent substitution or equivalent transformation
Technical solution is fallen within the scope of protection of the present invention.
Claims (10)
1. a kind of bioreactor with culture jar platform for placing characterized by comprising reaction kettle tank and host；Institute
Reaction kettle tank is stated detachably to install to the host；
The reaction kettle tank includes:
Tank body, for accommodating culture solution；With
Agitating paddle is used for stir culture liquid；
The host includes:
Body；
Peristaltic pump, for being the reaction kettle tank feed flow；
Controller, for controlling the peristaltic pump；With
Stirring motor, for driving the agitating paddle to rotate；
The peristaltic pump, the controller and the stirring motor are installed to the body；The tank body is detachably installed to institute
State body；The body is formed with the culture jar platform for placing that can put culture jar；The culture jar platform for placing
It is set to the lower section of the peristaltic pump.
2. the bioreactor according to claim 1 with culture jar platform for placing, which is characterized in that
The bioreactor with culture jar platform for placing, further includes: fixed device has culture solution for fixed storage
Culture jar；The fixed device is detachably set to the culture jar platform for placing.
3. the bioreactor according to claim 2 with culture jar platform for placing, which is characterized in that
The fixed device includes: retaining clip and movable clamp；The activity clamp is articulated to the retaining clip；Institute
It states movable clamp and the fixing groove of multiple culture jars for having culture solution for fixed storage is collectively formed in the retaining clip.
4. the bioreactor according to claim 3 with culture jar platform for placing, which is characterized in that
The activity clamp is formed with metal pin；The retaining clip is formed with mounting groove；The metal pin can be in institute
It states and is slided in mounting groove to adjust position of the movable clamp relative to the retaining clip；The side wall of the mounting groove is fixed
There is the magnet for attracting the metal pin；The magnet attracts the metal pin opposite to the fixed movable clamp
In the position of the retaining clip.
5. the bioreactor according to claim 4 with culture jar platform for placing, which is characterized in that
The fixed device further include: compress pin and holddown spring；The compression pin is slidingly attached to the movable clamp；It is described
Holddown spring, which sells application active force to the compression, makes the compression pin compress culture jar.
6. the bioreactor according to claim 1 with culture jar platform for placing, which is characterized in that
The agitating paddle is connected with the first connection structure；The stirring motor is connected with for docking with first connection structure
The second connection structure；When the tank body is connect with the body, first connection structure and second connection structure pair
It connects so that the stirring motor drives the agitating paddle rotation.
7. the bioreactor according to claim 6 with culture jar platform for placing culture jar platform for placing,
It is characterized in that,
One in first connection structure and second connection structure is convex block；First connection structure and described
Another in two connection structures is the groove that can be inserted into for the convex block；Connect in first connection structure and described second
When binding structure docks, the convex block is inserted into the groove so that first connection structure and the second connection structure energy
It is enough to rotate synchronously.
8. the bioreactor according to claim 1 with culture jar platform for placing, which is characterized in that
The host further include: touch control operation display screen；The touch control operation display screen is installed to the body；
The touch control operation display location is in the top of the culture jar platform for placing.
9. the bioreactor according to claim 1 with culture jar platform for placing, which is characterized in that
The host further include:
Oxygen sensor, for detecting the oxygen in the reaction kettle tank；
Temperature sensor, for detecting the temperature in the reaction kettle tank；With
PH sensor, for detecting the pH value in the reaction kettle tank；
The oxygen sensor, the temperature sensor and the pH sensor are detachably connected to the tank body.
10. the bioreactor according to claim 1 with culture jar platform for placing, which is characterized in that
The host further include:
Air filter, for being filtered to the gas being input in the reaction kettle tank；With
Gas-guide tube, for the filtered gas of the air filter to be directed into the reaction kettle tank；
The gas-guide tube is detachably connected to the tank body.
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| CN201811359575.7A CN109666583A (en) | 2018-11-15 | 2018-11-15 | Bioreactor with culture jar platform for placing |
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| CN201811359575.7A CN109666583A (en) | 2018-11-15 | 2018-11-15 | Bioreactor with culture jar platform for placing |
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| CN201811359575.7A Pending CN109666583A (en) | 2018-11-15 | 2018-11-15 | Bioreactor with culture jar platform for placing |
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Application publication date: 20190423 |
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