CN109663205A - A kind of nasal cavity slow releasing medicine feeder - Google Patents
A kind of nasal cavity slow releasing medicine feeder Download PDFInfo
- Publication number
- CN109663205A CN109663205A CN201910118017.XA CN201910118017A CN109663205A CN 109663205 A CN109663205 A CN 109663205A CN 201910118017 A CN201910118017 A CN 201910118017A CN 109663205 A CN109663205 A CN 109663205A
- Authority
- CN
- China
- Prior art keywords
- reservoir
- nasal cavity
- contact
- fixed frame
- slow releasing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 52
- 210000003928 nasal cavity Anatomy 0.000 title claims abstract description 40
- 210000000492 nasalseptum Anatomy 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims description 18
- 239000007788 liquid Substances 0.000 claims description 9
- 229920000742 Cotton Polymers 0.000 claims description 7
- 239000004698 Polyethylene Substances 0.000 claims description 7
- 239000000835 fiber Substances 0.000 claims description 7
- -1 polyethylene Polymers 0.000 claims description 6
- 229920000573 polyethylene Polymers 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000010985 leather Substances 0.000 claims description 2
- 239000011810 insulating material Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 abstract description 15
- 230000001225 therapeutic effect Effects 0.000 abstract description 5
- 230000002459 sustained effect Effects 0.000 abstract 1
- 239000012530 fluid Substances 0.000 description 15
- 239000010410 layer Substances 0.000 description 14
- 230000000694 effects Effects 0.000 description 8
- 210000001331 nose Anatomy 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 206010002198 Anaphylactic reaction Diseases 0.000 description 2
- 241000158526 Nasalis Species 0.000 description 2
- 230000036783 anaphylactic response Effects 0.000 description 2
- 208000003455 anaphylaxis Diseases 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 238000005213 imbibition Methods 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 206010016322 Feeling abnormal Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000012774 insulation material Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000000110 microvilli Anatomy 0.000 description 1
- 210000000537 nasal bone Anatomy 0.000 description 1
- 210000002184 nasal cartilage Anatomy 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 229940097496 nasal spray Drugs 0.000 description 1
- 210000003695 paranasal sinus Anatomy 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 229940126586 small molecule drug Drugs 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000010455 vermiculite Substances 0.000 description 1
- 229910052902 vermiculite Inorganic materials 0.000 description 1
- 235000019354 vermiculite Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229910001868 water Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/364—General characteristics of the apparatus related to heating or cooling by chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
Abstract
The invention belongs to via intranasal application administration and therapeutic equipment fields, more particularly to a kind of nasal cavity slow releasing medicine feeder, including fixed frame, reservoir, capillary and contact, the reservoir is arranged on fixed frame, contact is provided on the fixed frame, the reservoir is connect by capillary with contact, and the fixed frame is the clip structure that reservoir can be fixed on to nasal septum position, it is provided with medicine feeding hole on the reservoir, is provided with stopple on the medicine feeding hole.The present invention can make sustained drug be released slowly into nasal cavity, and via intranasal application plays therapeutic effect, so that patient is easier to receive, therapeutic effect is good.
Description
Technical field
The invention belongs to via intranasal application drug treatment apparatus fields, and in particular to a kind of nasal cavity slow releasing medicine feeder.
Background technique
Nose is the start-up portion and olfactory organ of respiration channel, is made of external nose, nasal cavity and 3 part of paranasal sinus, by
Nasal bone, nasal cartilages, nasalis and coating skin form.Nasal cavity by nasal septum be divided into left and right two chambers, it is preceding there is nostril to communicate with the outside world, after
It is connected to pharynx nasalis.Nasal cavity interior surface layers are chamber mucous membrane, and surface area is up to 150 cm2, and show there are a large amount of microvillus, under
Layer has capillary and capillary lymph duct abundant, is ideal drug administration approach, schneiderian membrance drug-delivery preparation have with
Under advantage:
1. bioavilability is high.Compared with oral administration, nasal-cavity administration can avoid drug and degrade in gastro-intestinal Fluid and liver head mistake
Effect has higher bioavilability, especially suitable for macromolecular polypeptides class drug.Small molecule drug bioavailability is close
Intravenous injection, but with more safety, non-invasive and acceptable.
2. efficiently.There are capillary network abundant in the surface area that schneiderian membrance is beaten again, mucous membrane lower section, and drug can absorb rapidly,
A small amount of drug can reach higher blood concentration.
3. drug is avoided to be destroyed by gastrointestinal tract, it is conducive to drug absorption.The drug being easily destroyed in gastrointestinal tract, polarity stomach greatly
Enteron aisle is difficult to the drug absorbed, schneiderian membrance can good absorption, the polypeptide and protein medicaments of macromolecular can also absorb
Preferably by Nasal mucosa absorption in the presence of promotor.
4. via intranasal application is administered to intracerebral.Chinese medicine thinks that five key of people communicates, evidence suggests nasal cavities connect with cerebrospinal fluid it is logical
Road, therefore can orient by schneiderian membrance and be administered to brain tissue.
In addition, nasal cavity is directly communicated with the external world, it is easy also to be susceptible to dust and pollen by various microorganism infections
Etc. anaphylaxis substance influence, be the high-incidence organ of allergic rhinitis.When nose is sick, often compares and feel bad, it is difficult to it treats, because
Nose areas is reached for drug and needs a very long time, and existing nasal spray therapeutic equipment can only provide high concentration in moment
Medical fluid, but the device of drug can be provided for nasal continuous there is presently no a, it is therefore desirable to one kind can continue for a long time
The device of via intranasal application sustained-release administration reduces the slight illness of patient.
Summary of the invention
To solve the above-mentioned problems, the present invention, which provides a kind of nasal cavity slow releasing medicine feeder, to provide medicine for nasal continuous
Object mitigates the slight illness of patient's nasal cavity.
The specific technical proposal is: a kind of nasal cavity slow releasing medicine feeder, including fixed frame, reservoir, capillary and contact, institute
It states reservoir to be arranged on fixed frame, contact is provided on the fixed frame, the reservoir is connected by capillary and contact
It connects, the fixed frame is the clip structure that reservoir can be fixed on to nasal septum position.Dosing is provided on the reservoir
Hole is provided with stopple on the medicine feeding hole.
Further, for the fixed mount setting at nasal septum position, the fixed frame is clip like, including left folder, right folder, bullet
Spring, circlip and pin；The part of the left and right clip intersection is provided with reservoir, and the both wings of the left and right clip are set respectively
It is equipped with contact, the reservoir is connect by capillary with contact.
Further, the fixed mount setting is at nasal septum position, and the fixed frame is N-shaped or "Ji" type, N-shaped or " several "
Reservoir is provided at the top of font fixed frame, the reservoir is that ribbon is coated at the top of N-shaped or "Ji" type fixed frame, institute
Reservoir is stated to connect by capillary with contact.At nasal septum position, reservoir is band for N-shaped or "Ji" type fixed mount setting
Shape is coated at the top of N-shaped or "Ji" type fixed frame, and human body nasal septum position can conduct heat to ribbon reservoir, make to store up
Fluid temperature and human body temperature in liquid capsule is close, so that patient is easier to receive, is unlikely to since medical fluid is excessively cool, the nose of human body
Chamber generates biggish stimulation, and patient is made to generate biggish mental burden.
Further, the contact is rotary table or cylindric, and the rotary table or cylindric middle part are provided with channel, the contact
By cotton, polyethylene perhaps fibers material contact periphery cotton, polyethylene or fibers material with preferable imbibition make
With the mode that can be good at persistently passing through slowly medical fluid seepage flow is delivered to nasal cavity；Channel breathes convenient for patient.This
There are three effect, one is to carry out nasal cavity to seep medicine treatment for sample processing；The other is being sterilized to the air for entering nasal cavity, prevent
The secondary invasion of germ improves curative effect；Third does not interfere patient to carry out eupnea.
Further, the channel is straight way, and the straight way is provided with 1 or more.
Further, the channel is helical form, and the helical channel is provided with 1 or more, increases the contact surface of air
Product, carries out further sterilization processing, good effect.
Further, the reservoir is the cryptomere of interior outer double-layer structure, and reservoir is the material for being able to bear 100 DEG C of temperature
It is made, prevents temperature is excessively high from scorching reservoir；Exothermic material is provided in outer layer blister cavities, liquid medicine is arranged in internal layer blister cavities.Storage
Liquid capsule is the cryptomere of interior outer double-layer structure, is provided with exothermic material in outer layer blister cavities, can liquid medicine to internal layer blister cavities into
Row heating, makes when ambient temperature is relatively low, can be heated to drug so that human body is easy to receive.The exothermic material is warm
Exothermic material is used in baby, is mainly made of materials such as iron powder, activated carbon, vermiculite, water, salt.Heating principle is that iron powder is supported naturally
Change, releases heat.Oxidation of iron powder is that comparison is slow under normal circumstances, and heat can not accumulate, under the action of active powdered carbon, iron
Powder and air contact area increase, so producing heat, Yan Heshui is to accelerate oxidation of iron powder, and exothermic material is existing
Technology.
Further, the reservoir outer layer is provided with insulating layer.
Further, the insulating layer is made of organic insulation material or leather substance.
The utility model has the advantages that
1, fixed mount setting is in nasal septum position, small in size, easy to carry, beauty.
2, reservoir can absorb the heat at patient's nasal septum position at nasal septum position so that the temperature of reservoir and
Human body temperature is almost the same, and very big stimulation will not be generated when the liquid of reservoir enters nasal cavity, and patient is easier to receive.
3, contact is rotary table or cylindric, and the rotary table or cylindric middle part are provided with channel, and the contact is by cotton, poly-
Ethylene perhaps fibers material contact periphery cotton, polyethylene or fibers material have preferable imbibition effect, can be fine
By medical fluid at the uniform velocity, slowly, lasting nasal cavity is delivered to by way of seepage flow；Channel breathes convenient for patient.Locate in this way
For reason there are three effect, one is to carry out nasal cavity to seep medicine treatment；The other is sterilizing to the air for entering nasal cavity, germ is prevented
Secondary invasion improves curative effect；Third does not interfere patient to breathe.
4, reservoir is the cryptomere of interior outer double-layer structure, and the exothermic material being provided in warmer in outer layer blister cavities can
It is heated with the liquid medicine to internal layer blister cavities, makes to heat drug when ambient temperature is relatively low so that human body
It is easy to receive.
6, physiological saline alternative medicine can be used in reservoir, be air-dried season and regional (such as Kunming) air for preventing
The dry damage to schneiderian membrance.
7, the drug in reservoir can be stored in contact, nose can be entered by two kinds of approach of seepage flow and breathing
Chamber is treated, and therapeutic effect is good；Be also possible to prevent the anaphylaxis such as dust in air and pollen, hazardous substances enter nasal cavity,
Have the function of anti-haze, nasal cavity and human body are protected.
Detailed description of the invention
Fig. 1 is a kind of schematic diagram of the nasal cavity slow releasing medicine feeder of embodiment 1
Fig. 2 is a kind of schematic diagram of the nasal cavity slow releasing medicine feeder of embodiment 2
Fig. 3 is the schematic diagram of round table-like contact
Fig. 4 is the schematic diagram of cylindric contact
Wherein, 1, fixed frame；101 left folders；102 right folders；103 springs；104 circlips；105 pins；2, reservoir；3, contact, 4,
Channel.
Specific embodiment
Embodiment 1
A kind of nasal cavity slow releasing medicine feeder as shown in Figure 1, the fixed frame 1 are arranged at nasal septum position, and the fixed frame 1 is
Clip like, including left folder 101, right folder 102, spring 103, circlip 104 and pin 105；102 intersection of the left folder 101 and right folder
Part be provided with reservoir 2, reservoir 2 is round pie, and the both wings of the left folder 101 and right folder 102 pass through plastic ring respectively
Or wire loop is provided withContact 3, the reservoir 2 by capillary withContact 3Connection.
Medical fluid is added by the medicine feeding hole of reservoir 2, beyond the Great Wall stopple；Pass through left folder 101, right folder 102, spring 103, circlip
104 and the clip like fixed frame of pin 105 infusion device is clipped in nasal septum position, left and right 2Contact 3Nostril is clogged, is had
Helped air filtering and medical fluid dialysis.Medical fluid is entered by capillary from reservoir 2Contact 3In, it travels further into nasal cavity.
In summer or the hotter weather in south, reservoir does not need heat supply generally, using single layer reservoir just
It can be the heat around nasal cavity to be reached in reservoir by the sheet metal of silica gel note lower part and is preheated to medical fluid.
In winter since temperature is lower, if the medical fluid of input is excessively cool, will increase nose feels bad degree, influences patient's
The state of mind.At this time with the double-deck blister cavities with self-heating effect, the medical fluid in internal layer blister cavities is suitably heated, then passes through
Contact, which enters nasal cavity, keeps patient more comfortable, helps to mitigate illness.
Embodiment 2
As shown in Fig. 2, the setting of fixed frame 1 is at nasal septum position, the fixed frame 1 is N-shaped or "Ji" type, N-shaped or " several " word
Reservoir 2 is provided at the top of type fixed frame 1, the reservoir 2 is that ribbon is coated at the top of N-shaped or "Ji" type fixed frame,
The reservoir 2 is connect by capillary with contact 3.N-shaped or "Ji" type fixed frame by rigid plastics or have certain bend
The metal material for taking intensity is made, such as steel.
Medical fluid is added by the medicine feeding hole of reservoir 2, beyond the Great Wall stopple；Contact 3 is protruded into nostril, nostril is clogged, medicine
Liquid is entered in nasal cavity by capillary from reservoir 2, and the channel on contact 3 can play the role of ventilation, and to air
It is sterilized and is filtered.
When reservoir 2 is the double-deck blister cavities, the position of medicine feeding hole should avoid bilayer vesicles cavity portion position, or directly pass through hair
Tubule carries out dosing to reservoir 2 by syringe.
At nasal septum position, reservoir 2 is that ribbon is coated on N-shaped or " several " word for N-shaped or the setting of "Ji" type fixed frame 1
At the top of type fixed frame, human body nasal septum position can conduct heat to ribbon reservoir, make fluid temperature in reservoir with
Human body temperature is close, so that patient is easier to receive, is unlikely to since medical fluid is excessively cool, and the nasal cavity of human body generates biggish stimulation,
Patient is set to generate biggish mental burden.
Embodiment 3
As shown in figure 3, contact 3 is round table-like, the central straight way for being provided with 1 or 1 or more, around with cotton, polyethylene
Or fibers material is made.
Embodiment 4
As shown in figure 4, contact 3 be it is cylindric, middle part is provided with 1 or more helical channel, around use cotton, polyethylene
Or fibers material is made.Contact can also be made of the cellular other materials with certain suction-operated, such as ceramic material
Deng.
Claims (9)
1. a kind of nasal cavity slow releasing medicine feeder, which is characterized in that including fixed frame, reservoir, capillary and contact, the liquid storage
Capsule is arranged on fixed frame, contact is provided on the fixed frame, the reservoir is connect by capillary with contact, described
Fixed frame is the clip structure that reservoir can be fixed on to nasal septum position, is provided with medicine feeding hole on the reservoir, described
Stopple is provided on medicine feeding hole.
2. a kind of nasal cavity slow releasing medicine feeder as described in claim 1, which is characterized in that the fixed mount setting is in nasal septum
Position, the fixed frame are clip like, including left folder, right folder, spring, circlip and pin；The portion of the left and right clip intersection
Set up separately and be equipped with reservoir, the both wings of the left and right clip are respectively arranged with contact, and the reservoir passes through capillary and contact
Connection.
3. a kind of nasal cavity slow releasing medicine feeder as described in claim 1, which is characterized in that the fixed mount setting is in nasal septum
Position, the fixed frame are N-shaped or "Ji" type, are provided with reservoir, the reservoir at the top of N-shaped or "Ji" type fixed frame
It is coated at the top of N-shaped or "Ji" type fixed frame for ribbon, the reservoir is connect by capillary with contact.
4. a kind of nasal cavity slow releasing medicine feeder as claimed in claim 2 or claim 3, which is characterized in that the contact is rotary table or circle
Column, the rotary table or cylindric middle part are provided with channel, and the contact is by cotton, polyethylene or fibers material.
5. such as a kind of described in any item nasal cavity slow releasing medicine feeders of claim 4, which is characterized in that the channel is straight way,
The straight way is provided with 1 or more.
6. such as a kind of described in any item nasal cavity slow releasing medicine feeders of claim 4, which is characterized in that the channel is spiral
Shape, the helical channel are provided with 1 or more.
7. a kind of nasal cavity slow releasing medicine feeder as described in claim 1, which is characterized in that the reservoir is the inside and outside double-deck knot
The cryptomere of structure, exothermic material is provided in outer layer blister cavities, and liquid medicine is arranged in internal layer blister cavities.
8. a kind of nasal cavity slow releasing medicine feeder as claimed in claim 7, which is characterized in that the reservoir outer layer is provided with guarantor
Warm layer.
9. a kind of nasal cavity slow releasing medicine feeder as claimed in claim 8, which is characterized in that the insulating layer is by organic heat-insulating material
Material or leather substance are made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910118017.XA CN109663205A (en) | 2019-02-15 | 2019-02-15 | A kind of nasal cavity slow releasing medicine feeder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910118017.XA CN109663205A (en) | 2019-02-15 | 2019-02-15 | A kind of nasal cavity slow releasing medicine feeder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109663205A true CN109663205A (en) | 2019-04-23 |
Family
ID=66152024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910118017.XA Pending CN109663205A (en) | 2019-02-15 | 2019-02-15 | A kind of nasal cavity slow releasing medicine feeder |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109663205A (en) |
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| WO2022020878A1 (en) * | 2020-07-13 | 2022-02-03 | Asap Breatheassist Pty Ltd | Agent delivery device, agent delivery system, and method of delivering an agent |
| CN112755373A (en) * | 2021-01-12 | 2021-05-07 | 天津中医药大学 | Nasal plug |
| CN112755373B (en) * | 2021-01-12 | 2022-10-04 | 天津中医药大学 | Nasal plug |
| CN113509628A (en) * | 2021-04-21 | 2021-10-19 | 河南科技大学第一附属医院 | Medicine injection appliance for otolaryngological nursing |
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