CN109637315A - A kind of prostate cancer simulation model and preparation method thereof - Google Patents
A kind of prostate cancer simulation model and preparation method thereof Download PDFInfo
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- CN109637315A CN109637315A CN201811529535.2A CN201811529535A CN109637315A CN 109637315 A CN109637315 A CN 109637315A CN 201811529535 A CN201811529535 A CN 201811529535A CN 109637315 A CN109637315 A CN 109637315A
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
Abstract
The invention discloses a kind of prostate cancer simulation models and preparation method thereof, are related to doctor's religion facility technology field.The method of the present invention includes: to make simulation model according to human prostate's entity structure；Simulation model includes prostate, vas deferens, seminal vesicle, urethra and tumor tissues, and with the left and right leaf of different color mark prostates, each structure relative position is identical as entity；Sagittal section materials are carried out to prostate tip and basal part respectively in simulation model: prostate tip and basal part are scaled off at 4~5mm perpendicular to urethra；Then it is successively cut along the direction interval 2~3mm parallel with urethra；Remaining 3~4mm of prostate interval is sliced, draw materials respectively each identifiable tumour, prostate inking incisxal edge and adjoin the prostata tissue of the tissue of each tumour, the tissue of other regions of anatomy, seminal vesicle basal part, the seminal vesicle tissue that materials adjoin prostate eradicates specimen sampling as prostate cancer and studies carefully for medical teaching and research.
Description
Technical field
The present invention relates to doctors to teach facility technology field more particularly to a kind of prostate cancer simulation model and preparation method thereof.
Background technique
With the change of people life style and eating habit, the disease incidence of domestic prostate cancer is in obvious ascendant trend.
As long as prostate cancer meets certain condition, feasible radical correction is simultaneously aided with other treatment means, thus Pathology Doctors ' will face
More and more prostate cancers eradicate sample.Correct processing prostate cancer radical cure sample is to obtain accurate histopathology and by stages
Assess, instruct the key factor of Clinical Processing.Now with the development of Standardized Training of Residents, more and more teaching doctors
Institute carries the training of pathology department's Resident Standardization, and trainee is mostly the resident of rigid registration, base's pathology
Section doctor and postgraduate, it is exactly to grasp to the materials of the big sample of pathology very few that these rule, which accompany student to have a common problem, is not known
How rationally to draw materials, and it is big for the materials difficulty as prostate cancer radical cure sample, it is desirable that and high sample is even more to have no way of doing it,
At this point, there is an urgent need to have a model for begining to learn pathologist practice materials.
Summary of the invention
In view of this, the embodiment of the invention provides a kind of prostate cancer simulation model and preparation method thereof, main purpose
Being to provide one kind can simulation model that is accurate and repeating prostate cancer radical cure specimen sampling.
In order to achieve the above objectives, invention broadly provides following technical solutions:
On the one hand, the embodiment of the invention provides a kind of production method of prostate cancer simulation model, the production methods
The following steps are included: making simulation model according to human lesion prostate entity structure；The simulation model includes prostate, defeated
Spermaduct, seminal vesicle, urethra and tumor tissues, in the simulation model relative position of each structure with lesion prostate entity knot
Structure is identical；
Along vertical or the urethral orifice end approximately perpendicular to prostate tip direction, the arrow of the prostate tip is cut
Shape section is organized as tip；
Along vertical or the urethra arrival end approximately perpendicular to prostate basal part direction, the prostate basal part is cut
Sagittal section, as basal part tissue；
Along the radial section of tip tissue, multiple tip tissues are obtained；
Along the radial section of the basal part tissue, multiple basal part tissues are obtained；
The tip tissue and the remaining simulation model after the basal part tissue will be cut as prostate ontology, along vertical
Directly in the direction at the urethral orifice end, multiple sagittal sections on the prostate ontology are cut, multiple prostatosis are obtained
Become tissue；
Cut the seminal vesicle on the prostate ontology；
The multiple tip tissue, the multiple basal part tissue, the multiple prostatic lesion tissue and
The seminal vesicle is studied carefully as prostate cancer radical cure specimen sampling model for medical teaching and research.
Preferably, being pasted on the section of two tip tissues adjacent in the multiple tip tissue removable two-sided
Glue；Removable double-sided adhesive is pasted on the section of two adjacent basal part tissues in the multiple basal part tissue；It is described more
Removable double-sided adhesive is pasted on the section of two adjacent prostatic lesion tissues in a prostatic lesion tissue.
Preferably, the tip tissue is to cut from from the urethral orifice end 4-5mm along vertical urethra direction
It takes；The basal part tissue is to cut from from the urethra arrival end 4-5mm along vertical urethra direction.
Preferably, the tip tissue is radially, successively it is sliced every 2-3m, obtains multiple tip tissues
Piece；The basal part tissue radially, is successively sliced every 2-3m, obtains multiple basal part tissues.
Preferably, the prostate ontology successively cuts arrow every 3-4mm along the direction at the vertical urethral orifice end
Shape section obtains multiple prostatic lesion tissues.
Preferably, the material of the simulation model is silica gel.
On the other hand, the embodiment of the invention provides a kind of prostate cancer simulation model, the simulation model and human body diseases
It is identical to become prostate entity structure；The simulation model includes prostate, vas deferens, seminal vesicle, urethra and tumor tissues, is imitated
Each structure relative position of true mode is identical as lesion prostate entity structure；
The prostate includes:
Tip tissue, is made of the resulting multiple tip tissues of the radial section organized along the tip；
Basal part tissue is made of the resulting multiple basal part tissues of the radial section along the basal part tissue；
Prostate ontology, by the resulting multiple prostatic lesion tissue groups of the vertically slice along the prostate ontology
At；
All tumor tissues in the prostate ontology；
The multiple tip tissue, the multiple basal part tissue, the multiple prostatic lesion tissue and
The seminal vesicle is studied carefully as prostate cancer radical cure specimen sampling for medical teaching and research.
Preferably, being arranged on the section of two tip tissues adjacent in the multiple tip tissue removable two-sided
The bonding of the multiple tip tissue is restored to the tip by removable double-sided adhesive and organized by glue, or along the section by institute
It states tip tissue and is separated into multiple tip tissues；
Removable double-sided adhesive is set on the section of two adjacent basal part tissues in the multiple basal part tissue, is led to
It crosses removable double-sided adhesive and the bonding of the multiple basal part tissue is restored to the basal part tissue, or will be described along the section
Basal part tissue is separated into multiple basal part tissues；
It is arranged on the section of two adjacent prostatic lesion tissues in the multiple prostatic lesion tissue removable
The bonding of the multiple prostatic lesion tissue is restored to the prostate ontology or edge by removable double-sided adhesive by double-sided adhesive
The prostate ontology is separated into multiple prostatic lesion tissues by the section.
Preferably, the shape of the tip tissue and the basal part tissue is bar shaped, the width of the bar shaped
Degree is 2-3mm；The prostatic lesion tissue with a thickness of 3-4mm；The material of the simulation model is silica gel.
Another aspect, the embodiment of the present invention make to obtain a kind of prostate cancer simulation model using the above method.
Compared with prior art, the beneficial effects of the present invention are:
The present invention designs the simulation model that a prostate cancer radical cure sample is made of silica gel product, eradicates by prostate cancer
The standard of specimen sampling, archetype is drawn materials, and is then by the sample splicing and recovery taken with removable double-sided adhesive with repeatable
Before materials, model may be reused；The present invention provides well for the teaching that current prostate cancer eradicates specimen sampling
Model also avoids begining to learn doctor because limited experience leads to mistake of drawing materials, brings puzzlement for the later period diagnosis of prostate cancer.
Detailed description of the invention
Fig. 1 is the production flow diagram for the prostate cancer simulation model that the embodiment of the present invention 1 provides；
Fig. 2 is the positive structure schematic for the prostate cancer simulation model that the embodiment of the present invention 2 provides；
Fig. 3 is the positive structure schematic for the prostate cancer simulation model that the embodiment of the present invention 2 provides；
Fig. 4 is the side structure schematic diagram for the prostate cancer simulation model that the embodiment of the present invention 2 provides.
Appended drawing reference
1 prostate, 101 tips tissue, 1011 tip tissues, 102 basal part tissues, 1021 basal part tissues, 103
Prostate ontology, 1031 prostatic lesion tissues；2 vas deferens, 3 seminal vesicles, 4 urethras.
Specific embodiment
For further illustrate the present invention to reach the technical means and efficacy that predetermined goal of the invention is taken, below with compared with
Good embodiment, to specific embodiment, technical solution, feature and its effect applied according to the present invention, detailed description is as follows.Under
Stating the special characteristic, structure or feature in multiple embodiments in bright can be combined by any suitable form.
Embodiment 1
As Figure 1-Figure 2, a kind of production method of prostate cancer simulation model, above-mentioned production method is comprising steps of press
Simulation model is made according to human prostate's entity structure；Above-mentioned simulation model includes prostate 1, vas deferens 2, seminal vesicle 3, urethra
4 and tumor tissues, a relative position (mould one identical as the prostate entity structure of lesion for above-mentioned each structure in simulation model
Sample, wherein tumor tissues position is common growth position)；Along vertical or direction (vertical side approximately perpendicular to 4 outlet end of urethra
To) sagittal section (omniplance) that cuts prostate tip 101, it is organized as tip；Edge is vertical or enters approximately perpendicular to urethra 4
The sagittal section that the direction (transverse direction or horizontal direction) at mouth end cuts prostate basal part 102 (i.e. neck of urinary bladder incisxal edge) (is cut entirely
Face), as basal part tissue；Along the radial section (along radius or diametrical direction) of above-mentioned tip tissue 101, multiple tips are obtained
Tissue 1011；Along the radial section (along radius or diametrical direction) of above-mentioned basal part tissue 102, multiple basal part tissues are obtained
Piece 1021；The remaining simulation model after above-mentioned tip tissue 101 and above-mentioned basal part tissue 102 will be cut as prostate ontology
103, the direction (vertical direction or identical as tip direction is cut) along vertical 4 direction outlet end of urethra cuts above-mentioned prostate sheet
Multiple sagittal sections (omniplance) on body 103 obtain multiple prostatic lesion tissues 1031 (i.e. respectively in prostate ontology
The upper tumour for cutting each big physical efficiency identification respectively, prostate inking edge and adjoin the tissue of each tumour, other solutions
Cut open the tissue (to evaluate multicentricity tumour) of position, the prostata tissue of seminal vesicle basal part)；Cut above-mentioned prostate ontology
On seminal vesicle 3；Above-mentioned multiple tip tissues 1011, above-mentioned multiple basal part tissues 1021, above-mentioned multiple prostatosis
Become tissue 1031 and above-mentioned seminal vesicle 3 to study carefully as prostate cancer radical cure specimen sampling for medical teaching and research.
As the preferred of above-described embodiment, according to the prototype structure of above-mentioned prostate tip in adjacent two panels prostate tip
Removable double-sided adhesive is pasted on the section of tissue；According to the prototype structure of above-mentioned prostate basal part in adjacent two panels prostate
Removable double-sided adhesive is pasted on the section of basal part tissue；According to the prototype structure of above-mentioned remaining simulation model in adjacent two panels
Removable double-sided adhesive is pasted on the section of prostate ontology tissue；The above-mentioned removable double-sided adhesive of stickup is for restoring above-mentioned emulation
Model repeats incision and uses；If not pasting removable double-sided adhesive, disposably to cure religion articles, two methods.
It is urinated along the direction at the urethral orifice end perpendicular to above-mentioned simulation model in distance as the preferred of above-described embodiment
Road 4-5mm cuts the tip tissue of above-mentioned prostate；Along the direction of the urethra arrival end perpendicular to above-mentioned simulation model, in distance
The basal part tissue of above-mentioned prostate is cut at urethra arrival end 4-5mm.
As the preferred of above-described embodiment, above-mentioned tip tissue and above-mentioned basal part tissue are radially at interval of 2-
3mm is successively sliced, and obtains multi-disc tip tissue and multi-disc basal part tissue.
It is above-mentioned imitative in above-mentioned residue according to mode identical with tip histotomy direction as the preferred of above-described embodiment
It is sliced (direction at vertical urethral orifice end is successively sliced) at interval of 3-4mm on true mode, obtains multi-disc prostatic lesion tissue
Piece.
As the preferred of above-described embodiment, the material of above-mentioned simulation model is silica gel.
Embodiment 2
As shown in Figure 3 and Figure 4, a kind of prostate cancer material simulation model, above-mentioned simulation model and human prostate's entity knot
Structure is identical；Above-mentioned simulation model includes prostate 1, vas deferens 2, seminal vesicle 3, urethra 4 and tumor tissues, each structure of simulation model
Relative position is identical as lesion prostate entity；Each structure relative position is identical as entity；Above-mentioned prostate includes: tip tissue
101, it is made of the resulting multi-disc tip tissue 1011 of the radial section organized along above-mentioned tip；Prostate basal part 102, by
It is formed along the resulting multi-disc basal part tissue 1021 of the radial section of above-mentioned basal part tissue；Prostate ontology 103, by along upper
The resulting multi-disc prostatic lesion tissue 1031 of vertically slice for stating prostate ontology forms；Above-mentioned multi-disc tip tissue
1011, above-mentioned multi-disc basal part tissue 1021, above-mentioned multi-disc pathological tissues piece 1031 and seminal vesicle 3 are used as prostate cancer-root
Specimen sampling is controlled to study carefully for medical teaching and research.
As the preferred of above-described embodiment, the material of above-mentioned simulation model is silica gel, is easy to be sliced and have true operation sense.
As the preferred of above-described embodiment, in above-mentioned multiple tip tissues on the section of two adjacent tip tissues
Removable double-sided adhesive is set, above-mentioned multiple tip tissue bondings are restored to by above-mentioned tip tissue or edge by removable double-sided adhesive
The tip tissue of recovery is separated into multiple tip tissues by section again.
Removable double-sided adhesive is set on the section of two adjacent basal part tissues in above-mentioned multiple basal part tissues, is led to
It crosses removable double-sided adhesive and above-mentioned multiple basal part tissues bonding is restored to above-mentioned basal part tissue, or along section by the base of recovery
Bottom tissue is separated into multiple basal part tissues again.
It is arranged on the section of two adjacent prostatic lesion tissues in above-mentioned multiple prostatic lesion tissues removable
Above-mentioned multiple prostatic lesion tissue bondings are restored to above-mentioned prostate ontology or edge by removable double-sided adhesive by double-sided adhesive
The prostate ontology of recovery is separated into multiple prostatic lesion tissues by section.
As the preferred of above-described embodiment, above-mentioned prostate tip tissue and above-mentioned prostate basal part tissue are item
The width of shape, above-mentioned bar shaped is 2-3mm, can be designed according to actual needs.
As the preferred of above-described embodiment, above-mentioned prostate ontology tissue with a thickness of 3-4mm, design the thickness, be
In order to allow tumor tissues more to show to study, can also design according to actual needs.
The simulation model for the prostate cancer radical cure sample that the present invention designs, the standard of specimen sampling is eradicated by prostate cancer,
Archetype is drawn materials, before being then materials for the sample splicing and recovery taken with reusable removable double-sided adhesive, makes mould
Type may be reused, and the teaching for eradicating specimen sampling for current prostate cancer provides good model, also avoid just studying medicine
Teacher brings puzzlement because limited experience leads to mistake of drawing materials, for the later period diagnosis of prostate cancer.
Place, those skilled in the art can not select from the prior art to the greatest extent in the embodiment of the present invention.
Disclosed above is only a specific embodiment of the invention, but scope of protection of the present invention is not limited thereto, is appointed
What those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, answer
It is included within the scope of the present invention.Therefore, protection scope of the present invention should be with above-mentioned scope of protection of the claims
It is quasi-.
Claims (10)
1. a kind of production method of prostate cancer simulation model, which is characterized in that the production method the following steps are included: according to
Human lesion prostate entity structure makes simulation model；The simulation model includes prostate, vas deferens, seminal vesicle, urethra
And tumor tissues, the relative position of each structure is identical as lesion prostate entity structure in the simulation model；
Along vertical or the urethral orifice end approximately perpendicular to prostate tip direction, the sagittal for cutting the prostate tip is cut
Face is organized as tip；
Along vertical or the urethra arrival end approximately perpendicular to prostate basal part direction, the arrow of the prostate basal part is cut
Shape section, as basal part tissue；
Along the radial section of tip tissue, multiple tip tissues are obtained；
Along the radial section of the basal part tissue, multiple basal part tissues are obtained；
Remaining simulation model after tip tissue and the basal part tissue will be cut as prostate ontology, edge perpendicular to
The direction at the urethral orifice end cuts multiple sagittal sections on the prostate ontology, obtains multiple prostatic lesion groups
Knit piece；
Cut the seminal vesicle on the prostate ontology；
The multiple tip tissue, the multiple basal part tissue, the multiple prostatic lesion tissue and described
Seminal vesicle is studied carefully as prostate cancer radical cure specimen sampling model for medical teaching and research.
2. a kind of production method of prostate cancer simulation model as described in claim 1, which is characterized in that the multiple tip
Removable double-sided adhesive is pasted on the section of two adjacent tip tissues in tissue；It is adjacent in the multiple basal part tissue
Two basal part tissues section on paste removable double-sided adhesive；Adjacent two in the multiple prostatic lesion tissue
Removable double-sided adhesive is pasted on the section of prostatic lesion tissue.
3. a kind of production method of prostate cancer simulation model as described in claim 1, which is characterized in that the tip tissue
It is to be cut from from the urethral orifice end 4-5mm along vertical urethra direction；The basal part tissue is from apart from the urine
At road arrival end 4-5mm, cut along vertical urethra direction.
4. a kind of production method of prostate cancer simulation model as described in claim 1, which is characterized in that the tip tissue
Radially, it is successively sliced every 2-3m, obtains multiple tip tissues；The basal part tissue radially, every
2-3m is successively sliced, and obtains multiple basal part tissues.
5. a kind of production method of prostate cancer simulation model as described in claim 1, which is characterized in that the prostate sheet
Body successively cuts sagittal section along the direction at the vertical urethral orifice end, every 3-4mm, obtains multiple prostatic lesions
Tissue.
6. a kind of production method of prostate cancer simulation model as described in claim 1, which is characterized in that the simulation model
Material be silica gel.
7. a kind of prostate cancer simulation model, which is characterized in that the simulation model and human lesion prostate entity structure phase
Together；The simulation model includes prostate, vas deferens, seminal vesicle, urethra and tumor tissues, and each structure of simulation model is with respect to position
It sets identical as lesion prostate entity structure；
The prostate includes:
Tip tissue, is made of the resulting multiple tip tissues of the radial section organized along the tip；
Basal part tissue is made of the resulting multiple basal part tissues of the radial section along the basal part tissue；
Prostate ontology is made of the resulting multiple prostatic lesion tissues of the vertically slice along the prostate ontology；
All tumor tissues in the prostate ontology；
The multiple tip tissue, the multiple basal part tissue, the multiple prostatic lesion tissue and described
Seminal vesicle is studied carefully as prostate cancer radical cure specimen sampling for medical teaching and research.
8. a kind of prostate cancer simulation model as claimed in claim 7, which is characterized in that phase in the multiple tip tissue
Removable double-sided adhesive is set on the section of two adjacent tip tissues, is glued the multiple tip tissue by removable double-sided adhesive
Conjunction is restored to the tip tissue, or tip tissue is separated into multiple tip tissues along the section；
Removable double-sided adhesive is set on the section of two adjacent basal part tissues in the multiple basal part tissue, by can
It moves double-sided adhesive and the bonding of the multiple basal part tissue is restored to the basal part tissue, or along the section by the substrate
Portion's tissue is separated into multiple basal part tissues；
It is arranged on the section of two adjacent prostatic lesion tissues in the multiple prostatic lesion tissue removable two-sided
The bonding of the multiple prostatic lesion tissue is restored to the prostate ontology by removable double-sided adhesive by glue, or along described
The prostate ontology is separated into multiple prostatic lesion tissues by section.
9. a kind of prostate cancer simulation model as claimed in claim 7, which is characterized in that the tip tissue and the base
The shape of bottom tissue piece is bar shaped, and the width of the bar shaped is 2-3mm；The prostatic lesion tissue with a thickness of 3-
4mm；The material of the simulation model is silica gel.
10. a kind of prostate cancer simulation model, which is characterized in that the simulation model is using any one of claim 1-6 institute
The method stated makes to obtain.
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Application publication date: 20190416 |