CN109620476A - Tibia middle and far section tumor type prosthesis and preparation equipment and preparation method thereof - Google Patents
Tibia middle and far section tumor type prosthesis and preparation equipment and preparation method thereof Download PDFInfo
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- CN109620476A CN109620476A CN201910137207.6A CN201910137207A CN109620476A CN 109620476 A CN109620476 A CN 109620476A CN 201910137207 A CN201910137207 A CN 201910137207A CN 109620476 A CN109620476 A CN 109620476A
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- prosthese
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- shin bone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2892—Tibia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30948—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using computerized tomography, i.e. CT scans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
Abstract
The invention relates to the technical field of auxiliary instruments, in particular to a tibia middle and far segment tumor type prosthesis and a preparation device and method thereof. The preparation device comprises an image acquisition system for acquiring tibia image data and a 3D printing system for printing a prosthesis model. According to the tibia middle and far segment tumor type prosthesis and the preparation device and method thereof, bilateral tibiofibula CT scanning is performed before an operation, reverse software is applied to reconstruct an affected side 3D tibiofibula, a tibia middle and far segment tumor type prosthesis image is made corresponding to a tibia malignant tumor predicted undercutting range, and visual understanding of a diseased tibia is obtained. A prosthesis handle and an ankle point are pressed tightly with a host tibia near end and a talus near end osteotomy surface respectively and are fused and fixed with the assistance of multiple screws, so that initial stability of connection of two ends of the prosthesis and host bone tissue is completed, bone ingrowth can be promoted by the prosthesis handle near end and a metal ankle point (a cavity formed in an ankle bone end), and postoperative long-term stability is enhanced.
Description
Technical field
The present invention relates to auxiliary instrument technical field, distal section tumorous type prosthese and its Preparation equipment in specially a kind of shin bone
And preparation method thereof.
Background technique
Currently, the bone defect in shin bone after distal section tumor resection is rebuild, there are mainly three types of selections: 1) big section homogeneous allogenic bone
Transplanting;2) implantation belt has artificial ankle prosthesis;3) distal section prosthese in the shin bone of implantation fusion tibial astragaloid joint.Wherein, with big
When section homogeneous allogenic bone transplantation rebuilds limbs, osteanagenesis is necessarily slow, allogeneic bone fracture, nonunion, rejection etc.
A possibility that complication occurs also increases accordingly.And the prosthese for having ankle-joint, it is locally answered using hinge restricted type prosthese
Power will be concentrated more, it is easier to the complication such as generation loosens, astragalus collapses, and use half limitation ankle prosthesis infectious-related complication such as
Astragalus prosthetic loosening and fibula shock still have generation, and rebuild ankle-joint surrounding ligaments very between metal prostheses and original bone
Difficulty, so best means are that distal section prosthese completes limb reconstruction in the shin bone using fusion tibial astragaloid joint.In clinical position,
Due to lacking most intuitive understanding to lesion shin bone, rear bone defect is cut to simulation root and is difficult to accurately be measured, leads to the scale of construction
Estimated difficulty in terms of distal end prosthetic designs are difficult in larger, complicated shin bone and such surgical procedure, in consideration of it,
It is proposed that distal section tumorous type prosthese and its Preparation equipment and preparation method thereof in a kind of shin bone.
Summary of the invention
The purpose of the present invention is to provide distal section tumorous type prosthese and its Preparation equipment and preparation method thereof in a kind of shin bone,
To solve mentioned above in the background art to lack due to lacking intuitive understanding to lesion shin bone, cutting rear bone defect to simulation root
The pre-designed scale of construction of distal section tumorous type prosthese is larger, structure is complicated in accurate measurement and shin bone and bring prosthetic designs manufacture
With a series of problems of application etc..To achieve the above object, on the one hand, the present invention provides distal section tumorous type in a kind of shin bone
Prosthese, the prosthese model include prosthese main body, and the bottom of the prosthese main body is provided with anklebone end, the inside at the anklebone end
Cavity is offered, anklebone end outer surface offers multiple location holes, is provided with prosthese shank at the top of the prosthese main body,
The outer surface of the prosthese shank offers multiple interlocking holes, and the prosthese shank is provided with close to prosthese interlocking hole side
Outer steel plate, the outer surface of the outer steel plate offer multiple screw holes, and the positioning hole is provided with screw, and the prosthese shank is handed over
It is connected between lockhole and the steel plate screw hole by self-locking nail.
On the other hand, it the present invention also provides a kind of Preparation equipment of distal section tumorous type prosthese in shin bone, is used to prepare above-mentioned
Shin bone in distal section tumorous type prosthese, the Preparation equipment includes the image acquisition system and use for acquiring shin bone image data
In the 3D printing system printed to the prosthese model, the image acquisition system is exported by reconstructing three-dimensional model module
It can be the image data of 3D printing system identification;
The image acquisition system include x-ray high pressure occur module, X-ray bulb module, collimating module, detecting module,
Analog-to-digital conversion module and data processing module;
The high tension voltage that module is used to generate x-ray occurs for the x-ray high pressure;
The X-ray bulb module issues the X-ray that can be used in detection;
The collimating module is used for the width of X-ray beam into adjusting, and determine subject cuts thickness degree;
The detecting module converts thereof into the electric signal of same intensity ratio for receiving Transmission X linear light;
The analog-to-digital conversion module is used to x-ray signal being changed into electric signal;
The data processing module is for being acquired and analyzing to data.
Preferably, the data processing module includes density resolution module, spatial resolution module, CT value calculating mould
Block and image gray-scale level processing module;
The density resolution module is used under low-contrast circumstances, poor to minimum density between two kinds of tissues of image
It is not differentiated;
The spatial resolution module is for identifying institutional framework space size;
The CT value computing module is for measuring CT image density values;
CT value of the described image grayscale processing module for each pixel in reconstruction matrix, and be transformed into accordingly from it is black to
The signal of white different depth.
Preferably, the reconstructing three-dimensional model module includes data import modul, data preprocessing module, Model Reconstruction
Module, model generation module and data export module;
The data import modul is used to the image data that image acquisition system acquires being directed into reconstructing three-dimensional model mould
In block;
The data preprocessing module is used to be filtered data and smoothing processing;
The Model Reconstruction module is for establishing 3-dimensional image model;
The model generation module is for generating complete 3-dimensional image model;
The data export module is used to export the picture format that can be identified by 3D printing system.
Preferably, the Model Reconstruction module includes isogonism sectored light model module, projection modified module, convolution mould
Block, discrete form module and back projection's module;
The isogonism sectored light model module is used for by waiting fan beam projections algorithm for reconstructing to rebuild image;
The projection modified module is used to assume the sampling interval of projection, and modifies to data from the sample survey;
The convolution module is used to carry out convolution to the projection of modification and receptance function;
The discrete form module is for calculating convolution thickness discrete form;
Back projection's module is for carrying out back projection's imaging.
Preferably, the 3D printing module includes slice module, print data conversion module, setting parameter module and vibration
Mirror laser scanning system;
The slice module is used to carry out slicing treatment based on stl file;
The print data conversion module by be sliced module be converted into printing bitmap data, and to the bitmap of print area into
Row typesetting also needs colour print to carry out color separation processing to color image;
The setting parameter module is used to be arranged the parameters of printing;
The lens vibrating type laser scanning system is for carrying out 3D printing.
On the other hand, the present invention also provides a kind of preparation method of distal section tumorous type prosthese in shin bone, pass through above-mentioned preparation
The step of equipment prepares distal section tumorous type prosthese in above-mentioned shin bone, the preparation method is as follows:
S1, the computer tomography data that same target object bilateral tibial is acquired by image acquisition system;
S2, step S1 tomographic data obtained is imported to reconstructing three-dimensional model module progress image processing operations,
Establish the threedimensional model of same target object bilateral tibial and the threedimensional model of bone tumour;
S3, osteotomy range and Osteotomy are determined based on digital shin bone and prosthese model, rear bone defect model is cut to simulation root
It encloses and is accurately measured, the strong side form that measurement data is accurately imported to three-dimensional simulation software is intended in simulation block, and side shin bone three is good for
Dimension module simulates the three-dimensional template of acquisition tumorous type prosthese main body template after osteotomy, and the prosthese three-dimensional template is passed through sagittal plane
Symmetrical mode mirror image obtains the three-dimensional template of Ipsilateral tumorous type prosthese main body to Ipsilateral;
S4, prosthese shank digital three-dimensional model: according to the position of proximal medullary cavity, diameter and depth design and proximal medullary cavity
The simulation prosthese shank matched, the trabecular bone structure that appearance is designed as with a thickness of 2.5cm obtain the threedimensional model of prosthese shank;
S5, design Digital anatomy steel plate, while interlocking hole is reserved in the threedimensional model of digital prosthese shank, design shin bone
Distal end ankle-joint location hole;
S6, the tumour prosthese three-dimensional digital model for obtaining step S5 import 3D printing terminal, after addition 3D printing support,
Toner and moulding process printing is selected to complete 1: 1 lesion shin bone and prosthese resin mould;
S7, shin bone and prosthese resin mould installation and debugging it is errorless after, tumour prosthese 3-dimensional digital that step S1-S5 is obtained
Model data imports 3D printing terminal and selects titanium alloy powder and moulding process to complete tumour prosthese after addition 3D printing support
Printing shaping, obtain the first product of tumorous type prosthese;
S8, the tumorous type prosthese first product that step S7 is obtained is post-processed, obtains tumorous type prosthese entity finished product.
Preferably, the threedimensional model of the bilateral tibial of same target object includes strong side shin bone threedimensional model in step S2
With Ipsilateral shin bone threedimensional model.
Preferably, the threedimensional model of the bilateral tibial in step S2 and the threedimensional model format of bone tumour are STL text
Part.
Preferably, the software of the reconstructing three-dimensional model module in step S2 is Mimics software.
Compared with prior art, beneficial effects of the present invention:
1, distal section tumorous type prosthese and its Preparation equipment and preparation method in the shin bone pass through preoperative progress bilateral tibiofibula
CT scan rebuilds Ipsilateral 3D tibiofibula using reverse software, and the corresponding estimated root of shin bone malignant tumour is cut remote in range production shin bone
Section tumorous type prosthese prosthese and ankle cave (cavity set by anklebone end) digitized video are debugged its size and location, and are obtained to lesion
The visual understanding of shin bone.
2, distal section tumorous type prosthese and its Preparation equipment and preparation method in the shin bone, by image and physical model to disease
Becoming shin bone has more intuitive understanding, cuts rear bone defect to simulation root and has carried out more accurate measurement, to make more rationally
The production of personalized prosthese and implantation scheme, while examination installation is carried out by resin lesion bone and prosthese, then further clarified
Prosthese and its component and root cut the match condition at each position of rear bone defect, are conducive to accomplish prosthese volume and structure most
Rationally, and to the problem of being likely to occur in art prediction scheme is made.
3, distal section tumorous type prosthese and its Preparation equipment and preparation method in the shin bone compensate for remote in clinical shin bone at present
The deficiency of section tumorous type prosthese improves recent functional rehabilitation journey so that body force credit cloth is more balanced after prosthese merging
Degree, prosthese shank and ankle cave (cavity set by anklebone end) are suppressed with proximal medullary cavity and astragalus osteotomy surface cancellous bone close and auxiliary respectively
It is fixed with more pieces of screw fusions, to complete the incipient stability that prosthese both ends are connect with host bone tissue, in addition, prosthese shank and gold
Host's Bone Ingrowth can be promoted by belonging to ankle cave (cavity set by anklebone end) porous surface, and stability at a specified future date is made to be guaranteed.
Detailed description of the invention
Fig. 1 is prosthese model structure schematic diagram of the invention;
Fig. 2 is prosthese model mounting structure schematic diagram in the embodiment of the present invention 1;
Fig. 3 is prosthese model mounting structure schematic diagram in the embodiment of the present invention 2;
Fig. 4 is anklebone end of the invention and anklebone mounting structure enlarged drawing;
Fig. 5 is image acquisition system structure chart of the invention;
Fig. 6 is 3D printing system structure chart of the invention;
Fig. 7 is that prosthese model of the invention prepares integral module figure;
Fig. 8 is image acquisition system module map of the invention;
Fig. 9 is that module circuit diagram occurs for x-ray high pressure of the invention;
Figure 10 is X-ray bulb module circuit diagram of the invention;
Figure 11 is data processing module figure of the invention;
Figure 12 is reconstructing three-dimensional model module map of the invention;
Figure 13 is Model Reconstruction module map of the invention;
Figure 14 is isogonism sectored light illustraton of model of the invention;
Figure 15 is 3D printing module map of the invention;
Figure 16 is the preparation method specific flow chart of distal tibia tumorous type prosthese of the invention.
In figure: 1, prosthese model;11, prosthese main body;12, anklebone end;13, cavity;14, location hole;15, prosthese shank;
16, interlocking hole;17, outer steel plate;18, screw hole;19, screw;110, inter-locking screw;111, interior steel plate.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " up time
The orientation or positional relationship of the instructions such as needle ", " counterclockwise " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of
The description present invention and simplified description, rather than the equipment of indication or suggestion meaning or element must have a particular orientation, with spy
Fixed orientation construction and operation, therefore be not considered as limiting the invention.
In the description of the present invention, the meaning of " plurality " is two or more, unless otherwise specifically defined.
Embodiment 1
On the one hand, the present invention provides distal section tumorous type prosthese in a kind of shin bone, as shown in Figure 1, include prosthese model 1, it is false
Body Model 1 includes prosthese main body 11, and the bottom of prosthese main body 11 is provided with anklebone end 12, and the inside at anklebone end 12 offers cavity
13,12 outer surface of anklebone end offers multiple location holes 14, and pelmatozoa 15, the appearance of shank 15 is arranged in the top of prosthese main body 11
Face offers multiple interlocking holes 16, and prosthese shank 11 is provided with outer steel plate 17, the appearance of outer steel plate 17 close to 16 side of interlocking hole
Face offers multiple screw holes 18, screw 19 is provided in location hole 14, between prosthese shank interlocking hole 16 and outer steel plate screw hole 18
It is connected by self-locking nail 110.Specifically, the size in prosthese shank interlocking hole 16 and the size of outer steel plate screw hole 18 are adapted, hand over
Pinning 110 and screw hole 18 are mating, and self-locking nail 110 is again and interlocking hole 16 is mating, convenient for by prosthese interlocking hole 16
Outer steel plate 17 and prosthese shank 15 are connected, and prosthese main body 11 is fixed on proximal tibia stump.
In the present embodiment, anklebone end 12 copies distal tibial ankle portion separation structure to design, so that the cavity at anklebone end 12
13 can be fitted on astragalus.Further, screw 19 and location hole 14 are mating, convenient for screw 19 is inserted into location hole
It is screwed into astragalus in 14, realizes the connection at anklebone end 12 and astragalus.
Prosthese in the present embodiment when in use, expands after host's proximal tibia stump pulp cavity row autogenous particulate bone pressure is filled out
Shank 12 is driven into pulp cavity by marrow later, and realization is fixed with pressure, and is passed through steel plate screw hole 18 by self-locking nail 110 and be screwed into prosthese
In interlocking hole 16, for connecting prosthese main body 11 and proximal tibia stump, complete what prosthese main body 11 was connect with host bone tissue
Incipient stability.
When in use, by the anklebone end 12 of prosthese main body 11 close to the astragalus side of host, so that the sky at anklebone end 12
Chamber 13 snaps on the astragalus of host, comprehensively considers the factors such as its function, operating difficulty, risk using ankle fusion side
Formula, as shown in figure 4, i.e. anklebone end 12 and astragalus are by the directly fixed fusion of screw, by removal astragalus surface cartilage and bone skin
Matter, so that exposure cancellous bone, tibial prosthesis distal end bone trabecula is directly contacted with cancellous bone, to achieve the purpose that Bone Ingrowth.
Embodiment 2
As second of embodiment of the invention, it is connect for the ease of further strengthening prosthese main body 11 with host bone tissue
Stability, the present invention staff is additionally provided with interior steel plate 111, as a kind of preferred embodiment, as shown in figure 3, interior steel plate 111
Size and the size of outer steel plate 17 are adapted, and the positional symmetry of the position of interior steel plate 111 and outer steel plate 17 is arranged, interior steel plate
111 and outer steel plate 17 be symmetricly set on 11 two sides of prosthese main body so that screw 19 through on outer steel plate 17 prosthese interlocking hole 16 insert
Enter host's shin bone, and screw 19 is pierced by through the other end in prosthese interlocking hole 16, reinforces fixing through interior steel plate 111, passes through interior steel
Plate 111 and outer steel plate 17 are fixed prosthese main body 11 and proximal tibia stump from two sides, improve the stability of integrated connection.
Embodiment 3
As the third embodiment of the invention, on the other hand, it is false that the present invention also provides distal section tumorous types in a kind of shin bone
The Preparation equipment of body is used to prepare distal section tumorous type prosthese in above-mentioned shin bone, as shown in Fig. 5, Fig. 7 and Fig. 8, Preparation equipment packet
Include the image acquisition system for acquiring shin bone image data and the 3D printing system for being printed to prosthese model 1, shadow
As the image data that acquisition system can be identified by the export of reconstructing three-dimensional model module for 3D printing system, image acquisition system
Module, X-ray bulb module, collimating module, detecting module, analog-to-digital conversion module and data processing occurs including x-ray high pressure
The high tension voltage that module is used to generate x-ray occurs for module, x-ray high pressure, and X-ray bulb module issues the X that can be used in detecting and penetrates
Line, collimating module are used for the width of X-ray beam into adjusting, and determine subject cuts thickness degree, and detecting module is for receiving
X-ray photon is penetrated, and converts thereof into the electric signal of same intensity ratio, analog-to-digital conversion module is used to x-ray signal being changed into electricity
Signal, data processing module is for being acquired and analyzing to data.
In the present embodiment, modular circuit occurs for x-ray high pressure as shown in figure 9, DC power supply is the three-phase by entering rack
480V alternating current obtains 670V direct current through three-phase bridge rectification, and supply current is up to 85A, and IGBT1-IGBT4 is 4 big function in figure
Rate trigger, controls its on-off by 4 individual control signals respectively, and control signal can change switching frequency or phase, root
Change according to output power size, transformer secondary exports high-frequency ac voltage, and peak value can provide 11A's up to 4.5kV
Electric current, this output voltage are added on 9 grades of multipliers, the voltage that every level-one is all made of concatenated diode and capacitor
Voltage is increased to about 9kV, current strength 5.5A at the 1st grade of end by peak detector (2 multiplication of voltage), and 9 grades of multipliers are total electricity
Pressure is increased to 82.5kV DC voltage, and current output capability reaches 0.4A.
Further, X-ray bulb modular circuit is as shown in Figure 10, and T1 is tube filament power transformer, secondary side in figure
The alternating voltage of generation is added on tube filament circuit after single-phase bridge rectification, provides electric current for filament, is gone here and there on the secondary side of T1
There is the primary coil of transformer T2, the current value size of the coil reflects the numerical value of heater current, through the rectification of T2 pair side, amplification
It after processing, is compared with desired filament current value, control filament transformer primary side is gone after error signal amplification, thus
Stable heater current is achieved the purpose that.
Specifically, what X-ray bulb module was made of bulb, heat exchanger and high-speed starting device, they are installed in machine
The rotating part of frame.
It is worth noting that detecting module includes crystal, photodiode and preamplifier, after x-ray bombards crystal,
X heat input is converted into luminous energy by crystal, then by photodiode is converted into electric current again, current values generally from zero to 500nA,
The electric current of diode output is added to the input terminal of preamplifier, generates zero voltage for arriving -10V in its output end, voltage it is exhausted
It is directly proportional to incident x-ray intensity to value.
In addition, analog-to-digital conversion module is designed based on V/F conversion circuit plate, V/F conversion circuit plate shares 12 pieces, and every piece includes
There are 100 channels, form 1200 analog/digital conversion channels altogether, conversion function is divided into the 2 grades: 1st grade first for detector output
Voltage signal (0~-10V) is converted into frequency signal (0~-2MHz), and the 2nd grade is signal adjustment, it receives switched frequency
The clock signal of rate signal and 4MHz generates 2 half-words, referred to as counting half-word and time half-word, and then this 2 half-words are from V/F
Conversion circuit is exported to data prediction circuit, the expression formula of this 2 half-words are as follows:
CHW=conversion frequency × data break -1
Integer part × 4 THW=CHW × 106/ conversion frequency
The image acquisition system of the Preparation equipment of distal tibia tumorous type prosthese in the present embodiment when in use, passes through X
The high tension voltage that module generates x-ray occurs for line high pressure, and the X-ray that can be used in detection is issued by X-ray bulb module, is passed through
Collimating module is to the width of X-ray beam into adjusting, and determine subject cuts thickness degree, passes through detecting module and receives Transmission X linear light
Son, and the electric signal of same intensity ratio is converted thereof into, x-ray signal is changed by electric signal by analog-to-digital conversion module, is led to
It crosses data processing module data are acquired and are analyzed.
Embodiment 4
As the 4th kind of embodiment of the invention, for the ease of at the image data that is acquired to image acquisition system
Reason, data processing module is arranged in the present invention staff, as a preferred embodiment of the present invention, as shown in figure 11, data processing
Module includes density resolution module, spatial resolution module, CT value computing module and image gray-scale level processing module, density resolution
Rate module is under low-contrast circumstances, differentiating minimum density difference between two kinds of tissues of image, spatial discrimination
Rate module is for identifying institutional framework space size, and CT value computing module is for measuring CT image density values, image ash
CT value of the rank processing module for each pixel in reconstruction matrix, and it is transformed into the signal of the different depth from black to white accordingly.
In the present embodiment, density resolution module refers under low comparative situation, and image is to minimum density between two kinds of tissues
The resolution capability of difference, is often expressed as a percentage, specific as follows: such as 0.2%, 5mm, 0.45Gy, indicates that the diameter of object is
5mm, when the acceptable dose of patient is 0.45Gy, the density resolution of CT is 0.2%, that is, indicates adjacent Liang Zhong tissue density value difference
When more than or equal to 0.2, CT, that is, distinguishable can not then be differentiated less than this value, and CT image density values are indicated with grayscale not at the same level,
Greyscale level is determined that N is binary digit, referred to as bit, and bit value is big by 2N, indicates to contain much information, the precision of quantization
Height, on the contrary then low, the principal element for influencing density resolution has thickness, x-ray dosage and noise etc..
Further, spatial resolution module refers in the case where high contrast, when density resolution is greater than 10%, image
To the distinguishing ability of institutional framework space size.It is specific: often to be indicated with interior demand pairs (Lp/cm) per cm, conversion is closed
System is the distinguishable smallest object diameter (mm) of 5+Lp/c
Demand pairs are more, and spatial resolution is higher, influence spatial resolution principal element have pixel, detector aperture,
Adjacent detector spacing, the convolutional filtering function of image reconstruction, data sampling, matrix, X-ray tube focal spot size and accuracy of machines
Deng.Wherein pixel is most important factor, and pixel is more in scan image matrix, and spatial resolution is higher.
Further, CT value computing module, mathematical expression formula are as follows:
I=I0e-μd
It wherein indicates the x-ray intensity after decaying by substance, indicates incident x-ray intensity, indicate the absorption coefficient of substance, table
The thickness for showing substance, after x-ray passes through human body different tissues, due to the density of the wavelength of x-ray, the atomic number of tissue and tissue
Difference, thus the absorption coefficient organized is different, what attenuation factor value indicated is usually the relative density of substance.
It is worth noting that under CT value computing module formula enters:
CT value=(μObject-μWater)/μWater*1000
The common tissue CT value table of human body
Tissue | CT value (Hu) | Tissue | CT value (Hu) |
Compact bone | > 250 | Liver | 45-75 |
Cancellous bone | 30-230 | Spleen | 35-55 |
Calcification | 80-300 | Kidney | 20-40 |
Blood | 50-90 | Pancreas | 25-55 |
Blood plasma | 25-30 | Thyroid gland | 35-50 |
Diffusate | > 15 | Fat | -50-100 |
Omission timber | < 18 | Muscle | 35-50 |
Hydrocrania | 3-8 | White matter of brain | 28-32 |
Water | 0 | Ectocinerea | 32-40 |
The data processing module of the Preparation equipment of distal tibia tumorous type prosthese in the present embodiment when in use, by close
It spends module resolution under low-contrast circumstances, minimum density difference between two kinds of tissues of image is differentiated, sky is passed through
Between module resolution institutional framework space size is identified, by CT value computing module measure CT image density values, pass through
The CT value of each pixel in image gray-scale level processing module reconstruction matrix, and it is transformed into the letter of the different depth from black to white accordingly
Number.
Embodiment 5
As the 5th kind of embodiment of the invention, the image data for the ease of acquiring to image acquisition system carries out three-dimensional
Model foundation, reconstructing three-dimensional model module is arranged in the present invention staff, as a preferred embodiment of the present invention, such as Figure 12 institute
Show, reconstructing three-dimensional model module includes data import modul, data preprocessing module, Model Reconstruction module, model generation module
With data export module, data import modul is used to the image data that image acquisition system acquires being directed into reconstructing three-dimensional model
In module, data preprocessing module is used to be filtered data and smoothing processing, and Model Reconstruction module is for establishing three-dimensional figure
As model, model generation module can be beaten for generating complete 3-dimensional image model, data export module for exporting by 3D
Print the picture format of system identification.
In shin bone in the present embodiment the reconstructing three-dimensional model module of the Preparation equipment of distal section tumorous type prosthese when in use,
The image data that image acquisition system acquires is directed into reconstructing three-dimensional model module by data import modul, passes through data
Preprocessing module is filtered to data and smoothing processing, establishes 3-dimensional image model by Model Reconstruction module, passes through model
Generation module generates complete 3-dimensional image model, the image that can be identified by 3D printing system by the export of data export module
Format.
Embodiment 6
As the 6th kind of embodiment of the invention, the image data for the ease of acquiring to image acquisition system carries out three-dimensional
It rebuilding, the present invention staff makes improvements Model Reconstruction module, as a preferred embodiment of the present invention, as shown in figure 13,
Model Reconstruction module includes isogonism sectored light model module, projection modified module, convolution module, discrete form module and back projection
Module, isogonism sectored light model module are used for by waiting fan beam projections algorithm for reconstructing to rebuild image, projection modification mould
Block is used to assume the sampling interval of projection, and modifies to data from the sample survey, and convolution module is for the projection and response to modification
Function carries out convolution, and discrete form module is in for carrying out back projection for calculating convolution thickness discrete form, back projection's module
Picture.
In the present embodiment, the algorithm for reconstructing design that isogonism sectored light model module is projected based on isogonism sectored light is such as schemed
Shown in 14, the detector for measuring data for projection is equally spacedly distributed in D1D2On arc, the radius of arc is 2D, and D is light source into image
The distance of the heart, expression of f (r, the φ) image in polar coordinates, Rβ(γ) indicates at the projection median stream flow angle that deflection is to be γ's
The data for projection that light generates is the distance that 0, L indicates from light source to pixel (r, φ) by its γ of the light at center
γ indicates the position angle of the light in the projection that deflection is β through pixel (r, φ)
Image f (r, φ) and fan-shaped projection Rβ(γ) has following relationships
Further, projection modified module algorithmic formula is as follows:
R'β(n α)=Rβ(nα)D1cosnα
Specifically, convolution module algorithmic formula is as follows:
In addition, discrete form modular algorithm formula is as follows:
It is worth noting that back projection's modular algorithm formula is as follows:
Approximation has:
Embodiment 7
As the 7th kind of embodiment of the invention, for the ease of carrying out 3D printing to prosthese model, 3D is arranged in the present invention staff
Print module, as a preferred embodiment of the present invention, as shown in Figure 6 and Figure 15,3D printing module includes slice module, beats
Data conversion module, setting parameter module and lens vibrating type laser scanning system are printed, slice module is used to be cut based on stl file
Piece processing, print data conversion module will be sliced module and be converted into printing bitmap data, and arrange the bitmap of print area
Version, also needs colour print to carry out color image color separation processing, and setting parameter module is used to be arranged each ginseng of printing
Number, lens vibrating type laser scanning system is for carrying out 3D printing.
In shin bone in the present embodiment the 3D printing module of the Preparation equipment of distal section tumorous type prosthese when in use, by cutting
Piece module is based on stl file and carries out slicing treatment, will be sliced module by print data conversion module and is converted into printing bitmap number
According to, and typesetting is carried out to the bitmap of print area, colour print is also needed to carry out color separation processing to color image, by setting
The parameters for setting parameter module setting printing, carry out 3D printing by lens vibrating type laser scanning system.
Embodiment 8
As the 8th kind of embodiment of the invention, on the other hand, it is false that the present invention also provides distal section tumorous types in a kind of shin bone
It is false to prepare distal section tumorous type in above-mentioned shin bone by the Preparation equipment of distal section tumorous type prosthese in above-mentioned shin bone for the preparation method of body
Body, as shown in figure 16, the step of preparation method are as follows:
S1, the computer tomography data that same target object bilateral tibial is acquired by image acquisition system;
S2, step S1 tomographic data obtained is imported to reconstructing three-dimensional model module progress image processing operations,
Establish the threedimensional model of same target object bilateral tibial and the threedimensional model of bone tumour;
S3, osteotomy range and Osteotomy are determined based on digital shin bone and prosthese model, rear bone defect model is cut to simulation root
It encloses and is accurately measured, the strong side form that measurement data is accurately imported to three-dimensional simulation software is intended in simulation block, and side shin bone three is good for
Dimension module simulates the three-dimensional template of acquisition tumorous type prosthese main body template after osteotomy, and the prosthese three-dimensional template is passed through sagittal plane
Symmetrical mode mirror image obtains the three-dimensional template of Ipsilateral tumorous type prosthese main body to Ipsilateral;
S4, prosthese shank digital three-dimensional model: according to the position of proximal medullary cavity, diameter and depth design and proximal medullary cavity
The simulation prosthese shank matched, the trabecular bone structure that appearance is designed as with a thickness of 2.5cm obtain the threedimensional model of prosthese shank;
S5, design Digital anatomy steel plate, while interlocking hole is reserved in the threedimensional model of digital prosthese shank, design shin bone
Distal end ankle-joint location hole;
S6, the tumour prosthese three-dimensional digital model for obtaining step S5 import 3D printing terminal, after addition 3D printing support,
Toner and moulding process printing is selected to complete 1: 1 lesion shin bone and prosthese resin mould;
S7, shin bone and prosthese resin mould installation and debugging it is errorless after, tumour prosthese 3-dimensional digital that step S1-S5 is obtained
Model data imports 3D printing terminal and selects titanium alloy powder and moulding process to complete tumour prosthese after addition 3D printing support
Printing shaping, obtain the first product of tumorous type prosthese;
S8, the tumorous type prosthese first product that step S7 is obtained is post-processed, obtains tumorous type prosthese entity finished product.
Further, the threedimensional model of the bilateral tibial in step S2 and the threedimensional model format of bone tumour are STL text
Part.
Specifically, the software of the reconstructing three-dimensional model module in step S2 is Mimics software.
In the present embodiment, there is more intuitive understanding to lesion shin bone by image and physical model, after cutting to simulation root
Bone defect has carried out more accurate measurement, to make more reasonably personalized prosthese production and implantation scheme.
Further, examination installation is carried out using resin lesion bone and prosthese, then specifies that prosthese and its shank are cut with root
The match condition of bone defect and proximal segment pulp cavity afterwards, it is most reasonable to be conducive to accomplish prosthese volume and structure, and to possible in art
The problem makes prediction scheme.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry
For personnel it should be appreciated that the present invention is not limited to the above embodiments, described in the above embodiment and specification is only the present invention
Preference, be not intended to limit the invention, without departing from the spirit and scope of the present invention, the present invention also has various
Changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by institute
Attached claims and its equivalent thereof.
Claims (10)
1. distal section tumorous type prosthese in a kind of shin bone, including prosthese model (1), it is characterised in that: the prosthese model (1) includes
The bottom of prosthese main body (11), the prosthese main body (11) is provided with anklebone end (12), and the inside of the anklebone end (12) opens up
Have cavity (13), anklebone end (12) outer surface offers multiple location holes (14), sets at the top of the prosthese main body (11)
It is equipped with prosthese shank (15), the outer surface of the prosthese shank (15) offers multiple interlocking holes (16), the prosthese shank
(15) it is provided with outer steel plate (17) close to interlocking hole (16) side, the outer surface of the outer steel plate (17) offers multiple spiral shells
Hole (18), the location hole (14) is interior to be provided with screw (19), passes through friendship between the interlocking hole (16) and the screw hole (18)
Lock screw (110) connection.
2. the Preparation equipment of distal section tumorous type prosthese, is used to prepare distal section in shin bone described in claim 1 in a kind of shin bone
Tumorous type prosthese, it is characterised in that: the Preparation equipment includes the image acquisition system and use for acquiring shin bone image data
In the 3D printing system printed to the prosthese model (1), the image acquisition system passes through reconstructing three-dimensional model module
Export can be the image data of 3D printing system identification;
The image acquisition system includes that module, X-ray bulb module, collimating module, detecting module, modulus occur for x-ray high pressure
Conversion module and data processing module;
The high tension voltage that module is used to generate x-ray occurs for the x-ray high pressure;
The X-ray bulb module issues the X-ray that can be used in detection;
The collimating module is used for the width of X-ray beam into adjusting, and determine subject cuts thickness degree;
The detecting module converts thereof into the electric signal of same intensity ratio for receiving Transmission X linear light;
The analog-to-digital conversion module is used to x-ray signal being changed into electric signal;
The data processing module is for being acquired and analyzing to data.
3. the Preparation equipment of distal section tumorous type prosthese in shin bone according to claim 2, it is characterised in that: at the data
Managing module includes density resolution module, spatial resolution module, CT value computing module and image gray-scale level processing module;
The density resolution module under low-contrast circumstances, to minimum density difference between two kinds of tissues of image into
Row is differentiated;
The spatial resolution module is for identifying institutional framework space size;
The CT value computing module is for measuring CT image density values;
CT value of the described image grayscale processing module for each pixel in reconstruction matrix, and be transformed into accordingly from black to white not
With the signal of depth.
4. the Preparation equipment of distal section tumorous type prosthese in shin bone according to claim 2, it is characterised in that: the three-dimensional mould
It includes data import modul, data preprocessing module, Model Reconstruction module, model generation module and data export that type, which rebuilds module,
Module;
The data import modul is for the image data that image acquisition system acquires to be directed into reconstructing three-dimensional model module;
The data preprocessing module is used to be filtered data and smoothing processing;
The Model Reconstruction module is for establishing 3-dimensional image model;
The model generation module is for generating complete 3-dimensional image model;
The data export module is used to export the picture format that can be identified by 3D printing system.
5. the Preparation equipment of distal section tumorous type prosthese in shin bone according to claim 4, it is characterised in that: the model weight
Modeling block includes isogonism sectored light model module, projection modified module, convolution module, discrete form module and back projection's module;
The isogonism sectored light model module is used for by waiting fan beam projections algorithm for reconstructing to rebuild image;
The projection modified module is used to assume the sampling interval of projection, and modifies to data from the sample survey;
The convolution module is used to carry out convolution to the projection of modification and receptance function;
The discrete form module is for calculating convolution thickness discrete form;
Back projection's module is for carrying out back projection's imaging.
6. the Preparation equipment of distal section tumorous type prosthese in shin bone according to claim 2, it is characterised in that: the 3D printing
Module includes slice module, print data conversion module, setting parameter module and lens vibrating type laser scanning system;
The slice module is used to carry out slicing treatment based on stl file;
The print data conversion module will be sliced module and be converted into printing bitmap data, and arrange the bitmap of print area
Version also needs colour print to carry out color separation processing to color image;
The setting parameter module is used to be arranged the parameters of printing;
The lens vibrating type laser scanning system is for carrying out 3D printing.
7. the preparation method of distal section tumorous type prosthese in a kind of shin bone, by shin bone described in claim 2-6 any one
Distal section tumorous type prosthese in shin bone described in the Preparation equipment preparation claim 1 of distal section tumorous type prosthese, it is characterised in that:
The step of preparation method, is as follows:
S1, the computer tomography data that same target object bilateral tibial is acquired by image acquisition system;
S2, step S1 tomographic data obtained is imported to reconstructing three-dimensional model module progress image processing operations, established
The threedimensional model of same target object bilateral tibial and the threedimensional model of bone tumour;
S3, osteotomy range and Osteotomy are determined based on digital shin bone and prosthese model, to simulation root cut rear bone defect range into
The accurate measurement of row, the strong side form that measurement data is accurately imported to three-dimensional simulation software are intended in simulation block, and side shin bone three-dimensional mould is good for
Pattern intends the three-dimensional template of acquisition tumorous type prosthese main body template after osteotomy, and the prosthese three-dimensional template is symmetrical by sagittal plane
Mode mirror image to Ipsilateral, obtain the three-dimensional template of Ipsilateral tumorous type prosthese main body;
S4, prosthese shank digital three-dimensional model: matched according to the position of proximal medullary cavity, diameter and depth design and proximal medullary cavity
Prosthese shank is simulated, the trabecular bone structure that appearance is designed as with a thickness of 2.5cm obtains the threedimensional model of prosthese shank;
S5, design Digital anatomy steel plate, while interlocking hole is reserved in the threedimensional model of digital prosthese shank, design distal tibial
Ankle-joint location hole;
S6, the tumour prosthese three-dimensional digital model for obtaining step S5 import 3D printing terminal, after addition 3D printing support, selection
1: 1 lesion shin bone and prosthese resin mould is completed in toner and moulding process printing;
S7, shin bone and prosthese resin mould installation and debugging it is errorless after, tumour prosthese three-dimensional digital model that step S1-S5 is obtained
Data import 3D printing terminal and select titanium alloy powder and moulding process to complete beating for tumour prosthese after addition 3D printing support
It is printed as type, obtains the first product of tumorous type prosthese;
S8, the tumorous type prosthese first product that step S7 is obtained is post-processed, obtains tumorous type prosthese entity finished product.
8. the preparation method of distal section tumorous type prosthese in shin bone according to claim 7, it is characterised in that: same in step S2
The threedimensional model of the bilateral tibial of one target object includes strong side shin bone threedimensional model and Ipsilateral shin bone threedimensional model.
9. the preparation method of distal section tumorous type prosthese in shin bone according to claim 7, it is characterised in that: in step S2
The threedimensional model of bilateral tibial and the threedimensional model format of bone tumour are stl file.
10. the preparation method of distal section tumorous type prosthese in shin bone according to claim 7, it is characterised in that: in step S2
Reconstructing three-dimensional model module software be Mimics software.
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