CN109620219A - A kind of attention rehabilitation training and appraisal procedure based on spectrum entropy - Google Patents

A kind of attention rehabilitation training and appraisal procedure based on spectrum entropy Download PDF

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CN109620219A
CN109620219A CN201910118759.2A CN201910118759A CN109620219A CN 109620219 A CN109620219 A CN 109620219A CN 201910118759 A CN201910118759 A CN 201910118759A CN 109620219 A CN109620219 A CN 109620219A
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rehabilitation training
attention
data
training
entropy
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田银
史玉盼
张慧玲
巫昱杉
杨利
张海勇
马亮
李扬
李沛洋
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Chongqing University of Post and Telecommunications
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
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Abstract

The present invention relates to a kind of attention rehabilitation trainings and appraisal procedure based on spectrum entropy, including S1: acquiring rehabilitation training object for the brain wave EEG related potential of simple phonologic attention task, and pre-process to EEG data;S2: the power spectral density of brain wave data after pretreatment is calculated;S3: spectrum entropy is calculated;S4: support vector machines is utilized, the attention EEG signal in rehabilitation training is trained characterized by composing entropy, obtains disaggregated model;S5: the tranquillization state data before acquisition rehabilitation training object training;S6: rehabilitation training is carried out to rehabilitation training object, and real-time grading is carried out to the EEG data in rehabilitation training;S7: being fed back according to real-time grading result, provides corresponding prompt, helps to focus on;S8: the tranquillization state data after acquisition rehabilitation training object training;S9: rehabilitation training effect is judged according to the variation of the spectrum entropy of training front and back tranquillization state data acquisition.

Description

A kind of attention rehabilitation training and appraisal procedure based on spectrum entropy
Technical field
The invention belongs to attention rehabilitation technique fields, are related to a kind of based on the attention rehabilitation training for composing entropy and assessment side Method.
Background technique
Currently, including drug therapy and non-drug therapy for the essential therapeutic arsenals of attention deficit person.With methylphenidate Central nervous excitation agent for representative is most common drug, rapid-action, significant effect, but since the action time of drug is short, And its drug side-effect is generated to patient, more and more patients are more likely to selection non-drug therapy.It is controlled in numerous non-drug In treatment means, EEG Biofeedback Training pays attention to because the advantages that its is safe and effective, curative effect is lasting, without side-effects is increasingly becoming treatment The Main way of power defect patient.A large amount of clinical test proves that electroencephalographic biofeedback therapy treats the curative effect of attention deficit With the therapeutic equivalence of central nervous excitation agent.
Occur combining the report to help children's hyperkinetic syndrome rehabilitation with game with BCI recent years.In report, θ/β For ratio as the index for distinguishing normal child and children's hyperkinetic syndrome children, applying game can be such that infant keeps easily, and light Facilitate θ/β in loose situation and tend to normal level, detect whether θ/β ratio in game process declines, does not play biological anti- Present effect.
Recently, more and more about the research of entropy, point out that ADHD patient is executing attention cognition times in existing research report The ApEn of right side frontal lobe is substantially less than normal person (referring to Linear and non-linear EEG analysis of in business adolescents with attention-deficit/hyperactivity disorder during a cognitive Task), this illustrates that entropy can be used as one reference index of attention deficit patient degree.Another report research discovery Patient's (consciousness is normal, agraphia with movement) of Healthy subjects and block comprehensive disease composes entropy in the state of active attention and compares Increase in tranquillization state and passive attention (referring to Toward an Attention-Based Diagnostic Tool for Patients With Locked-in Syndrome).This illustrates composing entropy can be used as whether be in one of attention state Index.
It refers to BCI now with some patents come the rehabilitation training to attention deficit patient is, but almost without People notices the evaluation index to rehabilitation training effect.For example test and instruction are reached come real-time human brain attention using EEG signal Practice purpose system (application number: CN 107024987) but the patent focus on be building for system, needle is not set forth in detail Selection to the characteristic of division in rehabilitation training is paid attention to, meanwhile, also therapeutic effect is not assessed.Patent is based on brain telecommunications Number feature extraction and its monitoring extraction system (application number: CN 108236464) in also refer to using entropy as feature progress Pay attention to rehabilitation training, but the spectrum entropy in the present invention is mainly different from using the method for comentropy, and the invention does not also provide health The evaluation index of multiple training effect.
Summary of the invention
In view of this, the purpose of the present invention is to provide a kind of attention rehabilitation training and appraisal procedure based on spectrum entropy, Using spectrum entropy as feature, to attention deficit, patient first trains disaggregated model, real to the data in rehabilitation training When classify, robot makes corresponding prompt according to classification results.Patient need to only keep body motionless and concentrate during this Attention watches the performance of robot, is adjusted according to the prompt of robot, to play the effect of rehabilitation training.This method Classified according to spectrum entropy as feature, active training effectively is carried out to patient, fundamentally treats attention deficit Illness;It is simultaneously that the spectrum entropy of training front and back is more convincing as the evaluation index of therapeutic effect.
In order to achieve the above objectives, the invention provides the following technical scheme:
A kind of attention rehabilitation training and appraisal procedure based on spectrum entropy, comprising the following steps:
S1: rehabilitation training object is acquired for the brain wave EEG related potential of simple phonologic attention task, and to EEG Data are pre-processed;
S2: the power spectral density of brain wave data after pretreatment is calculated;
S3: spectrum entropy is calculated;
S4: support vector machines is utilized, the attention EEG signal in rehabilitation training is trained characterized by composing entropy, is obtained To disaggregated model;
S5: the tranquillization state data before acquisition rehabilitation training object training;
S6: rehabilitation training is carried out to rehabilitation training object, and the EEG data in rehabilitation training is divided in real time Class;
S7: being fed back according to real-time grading result, provides corresponding prompt, helps to focus on;
S8: the tranquillization state data after acquisition rehabilitation training object training;
S9: rehabilitation training effect is judged according to the spectrum changes of entropy of training front and back tranquillization state data acquisition.
Further, EEG data is pre-processed described in step S1, including the segmentation of brain electricity, bad track are rejected, bad track reparation, filter Wave, baseline correction and artefact removal;
Wherein, brain electricity is segmented: 1. in off-line data, stimulation repeats to present, and each trial points are one section;2. in training In, it is desirable that the long-term state for keeping attention to concentrate, so every 10s is divided into one section;
Baseline correction: in data acquisition, outside noise and due to being tested itself, signal may be generated Drift, for the mistake for overcoming this phenomenon to generate, the data segment of 200ms is average as baseline before stimulating, post-stimulatory Data segment will subtract baseline;
Remove artefact: the artefacts such as removal eye movement blink.
Further, in step S2, pretreated data find out power spectral density P (f) using Welch method, by P (f) Standardization obtains the probability density function about frequency f
Further, in step S3, the power spectrum data by choosing full frequency band 0.5-45Hz calculates spectrum entropy
Further, in step S4, the training method of disaggregated model includes: that keyword the correct trail note of key is occurred For positive sample, key is not denoted as negative sample, is denoted as positive sample for what not no key occurred in no keyword, button operation It is denoted as negative sample, trains disaggregated model using SVM method.
The beneficial effects of the present invention are: the invention proposes spectrum entropy as the characteristic value for paying attention to classification, greatly improves The accuracy rate of classification.The variation of invention spectrum entropy provides a foundation for Quantified therapy effect.Meanwhile the invention belongs to base In the electroencephalographic biofeedback therapy of BCI, loop under entire cortex and cortex can be adjusted by adjusting the electrical activity of brain of sufferer Functional level, strengthen suitable adjusting, inhibit unfavorable adjusting, to really improve entire brain function.Before patient's training The spectrum entropy of tranquillization state data is compared afterwards, can effectively quantify rehabilitation training effect.
Detailed description of the invention
In order to keep the purpose of the present invention, technical scheme and beneficial effects clearer, the present invention provides following attached drawing and carries out Illustrate:
Fig. 1 is the attention rehabilitation training system figure based on spectrum entropy;
Fig. 2 is rehabilitation training detailed process figure;
Fig. 3 is off-line training marker samples flow chart;
Fig. 4 is the spectrum entropy comparison diagram of training front and back and standard (normal person).
Specific embodiment
Below in conjunction with attached drawing, a preferred embodiment of the present invention will be described in detail.
As shown in Figure 1-3, the present invention provides a kind of attention rehabilitation training and appraisal procedure based on spectrum entropy, wherein sharing Three roles, respectively attention deficit person, robot, therapist.Task about these three roles is allocated as follows:
Attention deficit person: wearing simple electrode cap, focus on keep and it is motionless, mentioned according to the voice of robot Show the behavior and consciousness for actively adjusting itself.
Robot: voice is made to patient according to the classification results of the EEG signal of patient and movement is fed back.
Therapist: helping patient to wear electrode cap, sets treatment time according to conditions of patients.
It should be noted that power handicapped wears easy electrode cap in rehabilitation training, connection brain electric data collecting is set Standby, robot can make corresponding reaction according to the state of patient.
Basic principle of the invention is when patient's attention is concentrated, and spectrum entropy increases, and when distractibility, spectrum entropy subtracts Few, spectrum entropy is classified as feature, and classification results are fed back to patient by the prompt of the feedback ends such as robot, allows patient The state of itself is adjusted in real time.
Need to acquire patient before attention training for simple phonologic attention task related potential, to off-line data into Spectrum entropy is extracted in row pretreatment.During off-line training, is there is into the correct trail of key in keyword and is denoted as positive sample, is not had Have key is denoted as negative sample, and no keyword occurs not to key is denoted as positive sample, and button operation is denoted as negative sample, Disaggregated model is trained using SVM method.
Tranquillization state data of the patient before and after training are acquired, according to the change of the spectrum entropy of patient's tranquillization state data acquisition twice Change to judge therapeutic effect, if the spectrum entropy of training front and back tranquillization state has apparent increase, proves that this is achieved well Therapeutic effect.
Patient is required to keep body motionless and attention concentration in attention training process, according to specific reading chapter to phase The number for answering keyword (for example, character in a novel, place, the adjective etc. of the description scenery in the article that describes the scenery) to occur carries out Learn by heart, and when robot reads keyword makes the sense organ input of required movement (such as: carry arm) Lai Jiaqiang patient.If process It is middle that robot provides corresponding prompt when there are abnormal conditions that are absent minded or tampering, if patient remind it is multiple Still attention can not be concentrated afterwards, and robot starts to dance to prompt more to attract patient's attention or patient to occur continuing moving more Can not still it stop after secondary, robot, which will sing, at this time helps patient to quiet down.After abnormal conditions disappear, robot is after resuming studies Book, after the completing setting time of the task, robot voice praises patient, completes this time to pay attention to training, as shown in Figure 2.
EEG data pretreatment includes that brain electricity is segmented, baseline correction, removes artefact, the operation such as filtering.Brain electricity segmentation: 1. from Line number according to when, stimulation repeats to present, and each trial point is one section.2. and in training, it is desirable that patient keeps attention to concentrate for a long time State, so for this part, every 10s is divided into one section.The purpose of brain electricity segmentation is will not according to the difference of stimulation Same sample extraction comes out, and is divided into isometric data segment for continuous stimulation event.Baseline correction: in data acquisition In, outside noise and due to being tested itself, signal may generate drift, for the mistake for overcoming this phenomenon to generate Accidentally, for the data segment of 200ms as baseline, post-stimulatory data segment will subtract baseline before stimulating.Remove artefact: removal eye The artefacts such as dynamic, blink.
Pretreated data find out power spectral density P (f) using Welch method.PSD is the function about frequency f, will The available probability density function about frequency f of P (f) standardization, such as formulaChoose full range The power spectrum data of section 0.5-45Hz calculates spectrum entropy
Therapeutic effect composes the comparison diagram of entropy as shown in figure 4,1,2 therapeutic effect of patient is obvious, and patient 3 does not play expected Therapeutic effect, 4 effect of patient are unobvious.
The shared of the EEG data under normal form is paid attention in order to realize, can develop a data management system.System is divided into general General family, therapist, data administrator, customer administrator, five kinds of roles of super keepe.Wherein, common user is auditing It can be obtained the permission for uploading data after, the data of upload need data administrator to audit, can be obtained down after the approval Carry the permission of data.If the user after succeeding in registration is badly in need of downloading data, the corresponding amount of money can be paid according to download.User After the data of upload are downloaded successfully by other users, corresponding remuneration can be obtained.Therapist is a kind of special user, is had free The permission of downloading data is obtained, but the data of the treatment acquisition of patient are automatically uploaded in system every time, referred to as the system Data.
Finally, it is stated that preferred embodiment above is only used to illustrate the technical scheme of the present invention and not to limit it, although logical It crosses above preferred embodiment the present invention is described in detail, however, those skilled in the art should understand that, can be Various changes are made to it in form and in details, without departing from claims of the present invention limited range.

Claims (5)

1. a kind of attention rehabilitation training and appraisal procedure based on spectrum entropy, it is characterised in that: the following steps are included:
S1: rehabilitation training object is acquired for the brain wave EEG related potential of simple phonologic attention task, and to EEG data It is pre-processed;
S2: the power spectral density of brain wave data after pretreatment is calculated;
S3: spectrum entropy is calculated;
S4: support vector machines is utilized, the attention EEG signal in rehabilitation training is trained characterized by composing entropy, is divided Class model;
S5: the tranquillization state data before acquisition rehabilitation training object training;
S6: rehabilitation training is carried out to rehabilitation training object, and real-time grading is carried out to the EEG data in rehabilitation training;
S7: being fed back according to real-time grading result, provides corresponding prompt, helps to focus on;
S8: the tranquillization state data after acquisition rehabilitation training object training;
S9: rehabilitation training effect is judged according to the spectrum changes of entropy of training front and back tranquillization state data acquisition.
2. the attention rehabilitation training and appraisal procedure according to claim 1 based on spectrum entropy, it is characterised in that: step S1 Described in EEG data pre-process, including brain electricity segmentation, bad track reject, bad track reparation, filtering, baseline correction and artefact removal;
Wherein, brain electricity is segmented: 1. in off-line data, stimulation repeats to present, and each trial points are one section;2. being wanted in training The long-term state for keeping attention to concentrate is sought, so every 10s is divided into one section;
Baseline correction: in data acquisition, outside noise and due to being tested itself, signal may generate drift It moves, for the mistake for overcoming this phenomenon to generate, the data segment of 200ms is as baseline before stimulating, and post-stimulatory data segment is all Subtract baseline;
Remove artefact: removal eye movement blink artefact.
3. the attention rehabilitation training and appraisal procedure according to claim 1 based on spectrum entropy, it is characterised in that: step S2 In, pretreated data find out power spectral density P (f) using Welch method, and P (f) standardization is obtained about frequency f's Probability density function
4. the attention rehabilitation training and appraisal procedure according to claim 1 based on spectrum entropy, it is characterised in that: step S3 In, the power spectrum data by choosing full frequency band 0.5-45Hz calculates spectrum entropy
5. the attention rehabilitation training and appraisal procedure according to claim 1 based on spectrum entropy, it is characterised in that: step S4 In, the training method of disaggregated model includes: that the correct trail of key is occurred in keyword to be denoted as positive sample, not the note of key For negative sample, it is denoted as positive sample by what not no key occurred in no keyword, button operation is denoted as negative sample, uses the side SVM Method trains disaggregated model.
CN201910118759.2A 2019-02-14 2019-02-14 A kind of attention rehabilitation training and appraisal procedure based on spectrum entropy Pending CN109620219A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110068466A (en) * 2019-04-30 2019-07-30 山东理工大学 Vehicle sound quality evaluation method based on brain wave
CN110200625A (en) * 2019-07-05 2019-09-06 郭长娥 A kind of brain brain neuroblastoma intensive training device and method
CN110584663A (en) * 2019-09-20 2019-12-20 深圳大学 Drug effect judgment device for herpes zoster and use method thereof
CN110652294A (en) * 2019-09-16 2020-01-07 清华大学 Creativity personality trait measuring method and device based on electroencephalogram signals
CN113192601A (en) * 2021-04-15 2021-07-30 杭州国辰迈联机器人科技有限公司 Attention deficit hyperactivity disorder rehabilitation training method and training task based on brain-computer interface
CN113679386A (en) * 2021-08-13 2021-11-23 北京脑陆科技有限公司 Method, device, terminal and medium for recognizing attention

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110068466A (en) * 2019-04-30 2019-07-30 山东理工大学 Vehicle sound quality evaluation method based on brain wave
CN110068466B (en) * 2019-04-30 2021-03-12 山东理工大学 Brain wave-based vehicle sound quality evaluation method
CN110200625A (en) * 2019-07-05 2019-09-06 郭长娥 A kind of brain brain neuroblastoma intensive training device and method
CN110652294A (en) * 2019-09-16 2020-01-07 清华大学 Creativity personality trait measuring method and device based on electroencephalogram signals
CN110584663A (en) * 2019-09-20 2019-12-20 深圳大学 Drug effect judgment device for herpes zoster and use method thereof
CN110584663B (en) * 2019-09-20 2022-04-12 深圳大学 Drug effect judgment device for herpes zoster and use method thereof
CN113192601A (en) * 2021-04-15 2021-07-30 杭州国辰迈联机器人科技有限公司 Attention deficit hyperactivity disorder rehabilitation training method and training task based on brain-computer interface
CN113679386A (en) * 2021-08-13 2021-11-23 北京脑陆科技有限公司 Method, device, terminal and medium for recognizing attention

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