CN109613593A - The gammaphoton active position methods of sampling, device, electronic equipment and storage medium - Google Patents

The gammaphoton active position methods of sampling, device, electronic equipment and storage medium Download PDF

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Publication number
CN109613593A
CN109613593A CN201811417389.4A CN201811417389A CN109613593A CN 109613593 A CN109613593 A CN 109613593A CN 201811417389 A CN201811417389 A CN 201811417389A CN 109613593 A CN109613593 A CN 109613593A
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active position
crystal
gammaphoton
target
effect
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CN109613593B (en
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吕振雷
魏清阳
刘亚强
江年铭
许天鹏
刘迈
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Chengdu Yongxin Medical Equipment Co ltd
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BEIJING YONGXIN MEDICAL EQUIPMENT Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/20Measuring radiation intensity with scintillation detectors
    • G01T1/202Measuring radiation intensity with scintillation detectors the detector being a crystal

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  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • High Energy & Nuclear Physics (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
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Abstract

The application proposes the gammaphoton active position methods of sampling, device, electronic equipment and storage medium in a kind of scintillation crystal detectors.Wherein, this method comprises: determining the crystal identification that gammaphoton is had an effect according to the output signal of scintillation crystal detectors, and obtain the probability distribution of crystals active position corresponding with crystal identification, and the probability distribution according to crystals active position, the position that gammaphoton is had an effect inside target crystal is sampled, to obtain the target effect site that gammaphoton is had an effect inside target crystal.Thus, probability distribution based on crystals active position, it is accurately sampled to the position that gammaphoton is had an effect inside target crystal, has accurately obtained the target effect site that crystals are had an effect, be the subsequent basis established based on target effect site accurate reconstruction image.

Description

The gammaphoton active position methods of sampling, device, electronic equipment and storage medium
Technical field
This application involves gammaphotons in terminal device technical field more particularly to a kind of scintillation crystal detectors to act on position Set the gammaphoton active position methods of sampling, device, electronic equipment and storage medium in methods of sampling scintillation crystal detectors.
Background technique
Scintillation crystal detectors are widely used in gamma photon detection, the basic principle is that being stopped simultaneously using scintillation crystal The energy of gammaphoton is converted into scintillation photons, detects gamma light indirectly using photon detector detection scintillation photons Spatial position, time and the energy information of son effect.Scintillation crystal detectors are widely used in all kinds of imaging systems, especially It is positron emission tomography (Positron Emission Tomography, PET) and single photon emission computed Computed tomography (SPECT) system (Single Photon Emission Computed Tomography, SPECT).PET and SPECT pass through Detection gammaphoton reconstructs the distribution of Radioactive isotope agent in vivo, to obtain the intracorporal metabolism of biology Etc. information, be widely used in the diagnosis of medicine, drug research and clinical disease.
In the discrete crystal array detector design being widely adopted at present, detector only can determine that gammaphoton occurs In which root scintillation crystal, and it can not determine the specific location that gammaphoton is had an effect inside the scintillation crystal.In image During reconstruction, it is thus necessary to determine that the line of response or projection line of each gammaphoton event, traditional method are often simple It is assumed that gammaphoton active position some determination point inside the central point or scintillation crystal of scintillation crystal incidence surface, However, above-mentioned this mode will lead to, in the position for deviateing system imaging central region, there are parallax effects, so as to cause space The decline of resolution ratio;Simultaneously this sparse discrete sampling will also result in image reconstruction process system transmission matrix calculate, Line of response or projection line position calculate and project the inaccurate of back projection's process calculating process, to affect reconstruction image The picture quality of spatial resolution and uniformity etc..Therefore, based on above-mentioned analysis, it can be seen that accurate to determine gamma light The specific location that son is had an effect inside the scintillation crystal can have a great impact for subsequent image procossing.Therefore, such as The problem of what accurate specific location for determining that gammaphoton is had an effect inside the scintillation crystal is current urgent need to resolve.
Summary of the invention
The application is intended to solve at least some of the technical problems in related technologies.For this purpose, the application First purpose is to propose that the gammaphoton active position methods of sampling in a kind of scintillation crystal detectors, this method are based on crystal The probability distribution of internal action position accurately samples to the position that gammaphoton is had an effect inside target crystal, quasi- The target effect site that crystals are had an effect really has been obtained, has been established to be subsequent based on target effect site accurate reconstruction image Basis.
Second purpose of the application is to propose gammaphoton active position sampling dress in a kind of scintillation crystal detectors It sets.
The third purpose of the application is to propose a kind of electronic equipment.
The 4th purpose of the application is to propose a kind of storage medium.
The 5th purpose of the application is to propose a kind of computer program product.
To achieve the above object, the application first aspect embodiment proposes gammaphoton in a kind of scintillation crystal detectors The active position methods of sampling, comprising: determine what gammaphoton was had an effect according to the output signal of the scintillation crystal detectors Crystal identification;Obtain the probability distribution of crystals active position corresponding with the crystal identification;According to the crystals The probability distribution of active position is sampled the position that gammaphoton is had an effect inside target crystal, to obtain gamma The target effect site that photon is had an effect inside the target crystal, wherein the target crystal and the crystal identification It is corresponding.
Optionally, further includes: obtain the probability value of each active position in the target crystal;According to each active position Probability value, pre-establish the probability distribution of the crystals active position.
Optionally, the probability value for obtaining each active position in the target crystal, comprising: according to each effect position The space coordinate of the spatial coordinated information, default incidence point set and each active position are respectively vertically mapped in target crystal table The space coordinate of location point on face determines each active position respectively corresponding gammaphoton incident angle respectively, wherein The location point and the default incidence point are in approximately the same plane;According to the corresponding gammaphoton of each active position It is every inside the target crystal to determine that gammaphoton reaches for the crystal arrangement information of incident angle and the scintillation crystal detectors The path length of the scintillator crystal materials passed through at a active position;Decaying according to gammaphoton in scintillator crystal materials is advised Rule and each corresponding path length of active position, obtain the probability of each active position in the target crystal Value.
Optionally, the probability value for obtaining each active position in the target crystal, comprising: S21, obtain the mesh Mark the active position sequence in crystal, wherein the active position sequence includes multiple active positions arranged in sequence; S22, for the current active position in the target crystal, according to the spatial coordinated information of current active position, default incidence The space coordinate and current active position of point are vertically mapped in the space coordinate of the location point on target crystal surface, determine institute State gammaphoton incident angle corresponding to current location;S23, according to the gammaphoton incident angle and the scintillation crystal The crystal arrangement information of detector determines gammaphoton to reach inside the target crystal and is passed through at the current active position Scintillator crystal materials path length;S24, according to gammaphoton scintillator crystal materials attenuation law and the path length Degree, obtains the probability value of current active position described in the target crystal;S25, according to the active position sequence, obtain with The adjacent next active position of the current active position, and using next active position as the current effect position It sets, and repeats the step S22 to S24, until traversing all active positions in the active position sequence.
Optionally, the probability distribution according to the crystals active position, to gammaphoton in target crystal The position that portion has an effect is sampled, to obtain the interacting goals position that gammaphoton is had an effect inside the target crystal It sets, comprising: according to the probability distribution of sampling prescription and the crystals active position, to gammaphoton inside target crystal The position having an effect carries out multiple sampling, and obtains multiple target effect sites according to sampling results.
To achieve the above object, the application second aspect embodiment proposes gammaphoton in a kind of scintillation crystal detectors Active position sampling apparatus, comprising: determining module, for determining gamma light according to the output signal of the scintillation crystal detectors The crystal identification that son is had an effect;First obtains module, acts on position for obtaining crystals corresponding with the crystal identification The probability distribution set;Processing module, for the probability distribution according to the crystals active position, to gammaphoton in target The position that crystals are had an effect is sampled, to obtain the target that gammaphoton is had an effect inside the target crystal Active position, wherein the target crystal is corresponding with the crystal identification.
Optionally, second module is obtained, for obtaining the probability value of each active position in the target crystal;Establish mould Block pre-establishes the probability distribution of the crystals active position for the probability value according to each active position.
Optionally, described second module is obtained, be specifically used for: according to the spatial coordinated information of each active position, preset The space that the space coordinate of incidence point and each active position are respectively vertically mapped in the location point on target crystal surface is sat Mark determines each active position respectively corresponding gammaphoton incident angle respectively, wherein the location point and described presets Incidence point is in approximately the same plane;It is brilliant according to the corresponding gammaphoton incident angle of each active position and the flashing The crystal arrangement information of bulk detector determines that gammaphoton reaches and is passed through at each active position inside the target crystal The path length of scintillator crystal materials;According to gammaphoton scintillator crystal materials attenuation law and each active position Corresponding path length obtains the probability value of each active position in the target crystal.
To achieve the above object, the application third aspect embodiment proposes a kind of electronic equipment, comprising: processor is deposited Reservoir, communication interface and bus;The processor, the memory and the communication interface are connected and are completed by the bus Mutual communication;The memory stores executable program code;The processor is stored by reading in the memory Executable program code run program corresponding with the executable program code, for executing the application first aspect The display methods at the application programs interface of embodiment.
To achieve the above object, the application fourth aspect embodiment proposes a kind of storage medium, wherein the storage is situated between Matter is for storing application program, and the application program for executing gal in scintillation crystal detectors described herein at runtime The horse photon active position methods of sampling.
To achieve the above object, the 5th aspect embodiment of the application proposes a kind of computer program product, wherein described Computer program product is taken out for executing gammaphoton active position in scintillation crystal detectors described herein at runtime Quadrat method.
In this application, crystal mark that gammaphoton is had an effect is determined according to the output signal of scintillation crystal detectors Know, and obtains the probability distribution of crystals active position corresponding with crystal identification, and according to crystals active position Probability distribution, the position that gammaphoton is had an effect inside target crystal is sampled, to obtain gammaphoton in mesh The target effect site that mark crystals are had an effect.Probability distribution as a result, based on crystals active position, to gamma light The position that son is had an effect inside target crystal is accurately sampled, and has accurately been obtained the target that crystals are had an effect and has been made It is the subsequent basis established based on target effect site accurate reconstruction image with position.
Detailed description of the invention
Fig. 1 is the gammaphoton active position methods of sampling in the scintillation crystal detectors according to the application one embodiment Flow chart;
Fig. 2 is the gammaphoton active position methods of sampling in the scintillation crystal detectors according to the application one embodiment Flow chart;
Fig. 3 is the refined flow chart according to the application one embodiment step 201;
Fig. 4 is the refined flow chart according to the step 201 of the application another embodiment;
Fig. 5 is active position A in target crystal in the application one embodiment, default incidence point B, mapping point C and enters Penetrate the schematic diagram of angle, θ;
Fig. 6 is gammaphoton active position sampling apparatus in the scintillation crystal detectors according to the application one embodiment Structural schematic diagram;
Fig. 7 is gammaphoton active position sampling apparatus in the scintillation crystal detectors according to another embodiment of the application Structural schematic diagram;
Fig. 8 is the structural schematic diagram according to the electronic equipment of the application one embodiment.
Specific embodiment
Embodiments herein is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached The embodiment of figure description is exemplary, it is intended to for explaining the application, and should not be understood as the limitation to the application.
Below with reference to the accompanying drawings gammaphoton active position sampling side in the scintillation crystal detectors of the embodiment of the present application is described Method, device, electronic equipment and storage medium.
Fig. 1 is the gammaphoton active position methods of sampling in the scintillation crystal detectors according to the application one embodiment Flow chart.
As shown in Figure 1, the gammaphoton active position methods of sampling includes: in the scintillation crystal detectors
S101 determines the crystal identification that gammaphoton is had an effect according to the output signal of scintillation crystal detectors.
Specifically, the gammaphoton active position methods of sampling in scintillation crystal detectors provided by the embodiments of the present application, it can To be executed by gammaphoton active position sampling apparatus in scintillation crystal detectors provided by the embodiments of the present application, which can be with It is configured in the imaging system with scintillation crystal detectors, for example, single photon emission computerized tomography system is (i.e. SPECT), positron emission tomography (i.e. PET) etc..
Wherein, crystal identification unique identification crystal can be indicated by a variety of expression crystal, for example, can be compiled with user's crystal Number indicate crystal identification, in another example, can be used letter indicate crystal identification.
Wherein, which indicates crystal identification with crystal number.
Wherein, it should be noted that the scintillation crystal detectors of the embodiment can be single layer scintillation crystal detectors, It can be the double-deck scintillation crystal detectors.
Wherein, single layer scintillation crystal detectors are that the flickering position in detector is arranged to make up by single layer scintillation crystal.
Wherein, the double-deck scintillation crystal detectors are that the flickering position in detector is arranged to make up by the double-deck scintillation crystal.
Wherein, which is described so that scintillation crystal detectors are single layer scintillation crystal detectors as an example.
As a kind of possible implementation, in the output signal for obtaining scintillation crystal detectors, can according to output signal, The co-ordinate position information of pixel hit is determined, then, according to the region for the pixel that each crystal prestored is hit Information is compared, and according to comparison result, determines the crystal identification that gammaphoton is had an effect.
S102 obtains the probability distribution of crystals active position corresponding with crystal identification.
It specifically, can be according to the probability of the crystal identification and crystals active position that prestore after obtaining crystal identification The corresponding relationship of distribution obtains the probability distribution of the corresponding crystals active position of the crystal identification.
S103 has an effect inside target crystal to gammaphoton according to the probability distribution of crystals active position Position be sampled, to obtain the target effect site that gammaphoton is had an effect inside target crystal, wherein target is brilliant Body is corresponding with crystal identification.
Wherein, active position is the position that gammaphoton is had an effect in target crystal.
The embodiment of property as an example can obtain in order to subsequent according to the active position reconstruction image extracted The probability distribution of crystals active position corresponding with crystal identification is taken, it can be according to the probability of the crystals active position point Cloth carries out random sampling to the position that gammaphoton is had an effect inside target crystal.
Calculating and the image reconstruction of system transmission matrix are carried out in order to be more accurate, as an example the embodiment party of property Formula, the position that can be had an effect inside target crystal according to the probability distribution of the crystals active position to gammaphoton into The multiple random sampling of row, and multiple target effect sites are obtained according to multiple random sampling result.Then, it is taken out by repeatedly random Multiple target effect sites of sample result carry out calculating and the image reconstruction process of subsequent transmission matrix.That is, should Target effect site in embodiment can be multiple.
Wherein, it should be noted that for each active position in target crystal, the probability of active position is not It together, can be that each active position be set according to the probability of active position in order to improve the accuracy of extracted target effect site Set Sampling weights, wherein the probability of active position is bigger, and corresponding Sampling weights are bigger.
The gammaphoton active position methods of sampling, is visited according to scintillation crystal in the scintillation crystal detectors of the embodiment of the present application The output signal for surveying device determines the crystal identification that gammaphoton is had an effect, and obtains crystals corresponding with crystal identification and make With the probability distribution of position, and according to the probability distribution of crystals active position, to gammaphoton inside target crystal The position having an effect is sampled, to obtain the target effect site that gammaphoton is had an effect inside target crystal.By This carries out the position that gammaphoton is had an effect inside target crystal based on the probability distribution of crystals active position Accurate sampling, has accurately obtained the target effect site that crystals are had an effect, and is subsequent accurate based on target effect site The basis that reconstruction image is established.
On the basis of based on the above embodiment, in order to can be according to the probability distribution of crystals active position, to gamma light The position that son is had an effect inside target crystal is sampled, and is determining gamma according to the output signal of scintillation crystal detectors Before the crystal identification that photon is had an effect, as shown in Fig. 2, this method may include:
Step 201, the probability value of each active position in target crystal is obtained.
Wherein, it should be noted that according to the difference of application scenarios, can obtain in several ways each in target crystal The probability value of active position, is illustrated below:
The first example
In this example, can according to the device identification of scintillation crystal detectors and the corresponding crystal identification of target crystal, From the probability value for obtaining each active position in target crystal in server.
After the probability value for obtaining each active position, place can also be normalized to the probability value of each active position Reason, so that the probability summation of each active position of crystals is 1, and according to the normalization probability of each active position Value, determines the probability distribution of the active position of crystals.
Second of example
In this example, as shown in figure 3, above-mentioned steps 201, may include:
Step 211, according to the spatial coordinated information of each active position, the space coordinate of default incidence point and each work It is respectively vertically mapped in the space coordinate of the location point on target crystal surface with position, determines each active position respectively respectively Corresponding gammaphoton incident angle, wherein location point and default incidence point are in approximately the same plane.
Step 212, according to the corresponding gammaphoton incident angle of each active position and scintillation crystal detectors Crystal arrangement information determines that gammaphoton reaches the scintillator crystal materials passed through at each active position inside target crystal Path length.
Wherein, the crystal arrangement information of scintillation crystal detectors can include but is not limited to crystal arrangement mode, crystal The information such as length, width and height.
Step 213, corresponding in the attenuation law of scintillator crystal materials and each active position according to gammaphoton Path length obtains the probability value of each active position in target crystal.
The embodiment of property as an example, according to gammaphoton scintillator crystal materials attenuation law index of coincidence Decaying.
Wherein, the attenuation law according to gammaphoton in scintillator crystal materials and the corresponding path of each active position Length, the formula for calculating the probability value of each active position in target crystal are as follows:
P (A)=e-μD (1)
Wherein, the P in formula (A) indicates the probability of crystals active position A, and μ is preparatory according to scintillator crystal materials Determining attenuation parameter, D indicate path length.
Step 202, according to the probability value of each active position, the probability distribution of crystals active position is pre-established.
The embodiment of property as an example can also be to each work after the probability value for obtaining each active position It is normalized with the probability value of position, so that the probability summation of each active position of crystals is 1, and according to The normalization probability value of each active position, determines the probability distribution of the active position of crystals.
The third example
In this example, as shown in figure 4, above-mentioned steps 201 may include:
S21, active position sequence in target crystal is obtained, wherein active position sequence includes multiple arranging in sequence The active position of column;
S22, for the current active position in target crystal, according to the spatial coordinated information of current active position, default The space coordinate of incidence point and current active position are vertically mapped in the space coordinate of the location point on target crystal surface, really Gammaphoton incident angle corresponding to settled front position.
S23, according to the crystal arrangement information of gammaphoton incident angle and scintillation crystal detectors, determine that gammaphoton arrives The path length of the scintillator crystal materials passed through at current active position inside up to target crystal.
S24, according to gammaphoton in the attenuation law and path length of scintillator crystal materials, obtain in target crystal current The probability value of active position.
S25 obtains the next active position adjacent with current active position according to active position sequence, and will be next A active position repeats step S22 to S24 as current active position, until the institute in ergodic action position sequence There is active position.
Specifically, according to active position sequence, obtain the next active position adjacent with current active position, and will under One active position judges whether current active position is the last one work in active position sequence as current active position With position, if so, determining all active positions traversed in active position sequence.If it is not, then repeating step S22 To S23.
The probability value for determining active position A in target crystal is described below with reference to Fig. 2, it is assumed that according to scintillation crystal The crystal number that the output signal of detector determines that gammaphoton is had an effect is crystal 8.
Firstly, the information such as space coordinate of crystal 8 being had an effect according to gammaphoton, calculate gammaphoton entrance crystal Angle, θ;
Specifically, it is sat according to the space of the space coordinate of default incidence point B, the space coordinate of active position A and C point Mark.
Wherein, C point is that active position A is vertically mapped to corresponding location point on 8 surface of crystal.
Wherein, it should be noted that location point C and default incidence point A are in approximately the same plane.
Then, it according to crystal arrangement mode in gammaphoton entrance crystal angle and detector, calculates gammaphoton and reaches The path length D for the scintillator crystal materials that the place crystals active position A (x, y, z) passes through;
Later, according to above-mentioned formula (1), the probability value of active position A is calculated.
Wherein, it is to be understood that, can be by identical with active position A for other active positions in the crystal Mode calculates the probability value of other active positions, which repeats no more.
In order to realize above-described embodiment, the present invention also proposes that gammaphoton active position is taken out in a kind of scintillation crystal detectors Sampling device.
Fig. 6 is gammaphoton active position sampling apparatus in scintillation crystal detectors according to an embodiment of the invention Structural schematic diagram.
As shown in fig. 6, in the scintillation crystal detectors gammaphoton active position sampling apparatus include determining module 110, First obtains module 120 and processing module 130, in which:
Determining module 110 determines the crystalline substance that gammaphoton is had an effect for the output signal according to scintillation crystal detectors Body mark.
First obtains module 120, for obtaining the probability distribution of crystals active position corresponding with crystal identification.
Processing module 130, for the probability distribution according to crystals active position, to gammaphoton in target crystal The position that portion has an effect is sampled, to obtain the target effect site that gammaphoton is had an effect inside target crystal, Wherein, target crystal is corresponding with crystal identification.
Wherein, it should be noted that aforementioned that the gammaphoton active position methods of sampling in scintillation crystal detectors is implemented The explanation of example is also applied for gammaphoton active position sampling apparatus in the scintillation crystal detectors of the embodiment, herein not It repeats again.
Gammaphoton active position sampling apparatus, is visited according to scintillation crystal in the scintillation crystal detectors of the embodiment of the present application The output signal for surveying device determines the crystal identification that gammaphoton is had an effect, and obtains crystals corresponding with crystal identification and make With the probability distribution of position, and according to the probability distribution of crystals active position, to gammaphoton inside target crystal The position having an effect is sampled, to obtain the target effect site that gammaphoton is had an effect inside target crystal.By This carries out the position that gammaphoton is had an effect inside target crystal based on the probability distribution of crystals active position Accurate sampling, has accurately obtained the target effect site that crystals are had an effect, and is subsequent accurate based on target effect site The basis that reconstruction image is established.
In one embodiment of the application, on the basis of shown in Fig. 6, as shown in fig. 7, the device can also include:
Second obtains module 140, for obtaining the probability value of each active position in target crystal.
Module 150 is established, for the probability value according to each active position, pre-establishes the general of crystals active position Rate distribution.
Wherein, it should be noted that according to the difference of application scenarios, can obtain in several ways each in target crystal The probability value of active position, is illustrated below:
The first example
In this example, second obtain module 140 can device identification according to scintillation crystal detectors and target crystal Corresponding crystal identification, from the probability value for obtaining each active position in target crystal in server.
After the second acquisition module 140 obtains the probability value of each active position, establishing module can be to each active position Probability value be normalized so that the probability summation of each active position of crystals is 1, and according to each work With the normalization probability value of position, the probability distribution of the active position of crystals is determined.
Second of example
In this example, second module is obtained, be specifically used for: according to the spatial coordinated information of each active position, preset The space that the space coordinate of incidence point and each active position are respectively vertically mapped in the location point on target crystal surface is sat Mark determines each active position respectively corresponding gammaphoton incident angle respectively, wherein location point at default incidence point In in approximately the same plane;According to the crystalline substance of each active position corresponding gammaphoton incident angle and scintillation crystal detectors Body arrangement information determines that gammaphoton reaches the road of the scintillator crystal materials passed through at each active position inside target crystal Electrical path length;According to gammaphoton scintillator crystal materials attenuation law and the corresponding path length of each active position, Obtain the probability value of each active position in target crystal.
Wherein, second the detailed process that module 140 obtains the probability value of each active position in target crystal is obtained, such as schemed Shown in 3, details are not described herein again.
Second of example, the second acquisition module 140 can obtain each effect in target crystal by mode as shown in Figure 4 The probability value of position.
The detailed process for obtaining the probability value of each active position in 140 target crystal of module about second, reference can be made on The corresponding portion of method description is stated, details are not described herein again.
In order to realize above-described embodiment, the application also proposes a kind of electronic equipment.
Fig. 8 is the structural schematic diagram according to the electronic equipment of the application one embodiment.
As shown in figure 8, the electronic equipment includes processor 81, memory 82, communication interface 83 and bus 84, in which:
Processor 81, memory 82 and communication interface 83 connect by bus 84 and complete mutual communication;Memory 82 storage executable program codes;Processor 81 is run by reading the executable program code stored in memory 82 and can The corresponding program of program code is executed, for executing gammaphoton active position in the scintillation crystal detectors in upper embodiment The methods of sampling.
The electronic equipment of the embodiment of the present application determines that gammaphoton is made according to the output signal of scintillation crystal detectors Crystal identification, and the probability distribution of crystals active position corresponding with crystal identification is obtained, and according in crystal The probability distribution of portion's active position is sampled the position that gammaphoton is had an effect inside target crystal, to obtain gal The target effect site that horse photon is had an effect inside target crystal.Probability point as a result, based on crystals active position Cloth accurately samples to the position that gammaphoton is had an effect inside target crystal, has accurately obtained crystals generation The target effect site of effect is the subsequent basis established based on target effect site accurate reconstruction image.
In order to realize above-described embodiment, the application also proposes a kind of imaging system, which includes above-described embodiment Scintillation crystal detectors in gammaphoton active position sampling apparatus.
Wherein, imaging system can be disconnected for single photon emission computerized tomography system (i.e. SPECT), positron emission Layer imaging system (i.e. PET) etc..
In order to realize above-described embodiment, the application also proposes a kind of storage medium, wherein storage medium is for storing application Program, application program is for gammaphoton active position sampling side in the scintillation crystal detectors of execution the application at runtime Method.
In order to realize above-described embodiment, the application also proposes a kind of computer program product, wherein computer program product The gammaphoton active position methods of sampling in scintillation crystal detectors for executing the application at runtime.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is contained at least one embodiment or example of the application.In the present specification, schematic expression of the above terms are not It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples It closes and combines.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include at least one this feature.In the description of the present application, the meaning of " plurality " is at least two, such as two, three It is a etc., unless otherwise specifically defined.
Any process described otherwise above or method description are construed as in flow chart or herein, and expression includes It is one or more for realizing specific logical function or process the step of executable instruction code module, segment or portion Point, and the range of the preferred embodiment of the application includes other realization, wherein can not press shown or discussed suitable Sequence, including according to related function by it is basic simultaneously in the way of or in the opposite order, Lai Zhihang function, this should be by the application Embodiment person of ordinary skill in the field understood.
Expression or logic and/or step described otherwise above herein in flow charts, for example, being considered use In the order list for the executable instruction for realizing logic function, may be embodied in any computer-readable medium, for Instruction execution system, device or equipment (such as computer based system, including the system of processor or other can be held from instruction The instruction fetch of row system, device or equipment and the system executed instruction) it uses, or combine these instruction execution systems, device or set It is standby and use.For the purpose of this specification, " computer-readable medium ", which can be, any may include, stores, communicates, propagates or pass Defeated program is for instruction execution system, device or equipment or the dress used in conjunction with these instruction execution systems, device or equipment It sets.The more specific example (non-exhaustive list) of computer-readable medium include the following: there is the electricity of one or more wirings Interconnecting piece (electronic device), portable computer diskette box (magnetic device), random access memory (RAM), read-only memory (ROM), erasable edit read-only storage (EPROM or flash memory), fiber device and portable optic disk is read-only deposits Reservoir (CDROM).In addition, computer-readable medium can even is that the paper that can print described program on it or other are suitable Medium, because can then be edited, be interpreted or when necessary with it for example by carrying out optical scanner to paper or other media His suitable method is handled electronically to obtain described program, is then stored in computer storage.
It should be appreciated that each section of the application can be realized with hardware, software, firmware or their combination.Above-mentioned In embodiment, software that multiple steps or method can be executed in memory and by suitable instruction execution system with storage Or firmware is realized.It, and in another embodiment, can be under well known in the art for example, if realized with hardware Any one of column technology or their combination are realized: having a logic gates for realizing logic function to data-signal Discrete logic, with suitable combinational logic gate circuit specific integrated circuit, programmable gate array (PGA), scene Programmable gate array (FPGA) etc..
Those skilled in the art are understood that realize all or part of step that above-described embodiment method carries It suddenly is that relevant hardware can be instructed to complete by program, the program can store in a kind of computer-readable storage medium In matter, which when being executed, includes the steps that one or a combination set of embodiment of the method.
It, can also be in addition, can integrate in a processing module in each functional unit in each embodiment of the application It is that each unit physically exists alone, can also be integrated in two or more units in a module.Above-mentioned integrated mould Block both can take the form of hardware realization, can also be realized in the form of software function module.The integrated module is such as Fruit is realized and when sold or used as an independent product in the form of software function module, also can store in a computer In read/write memory medium.
Storage medium mentioned above can be read-only memory, disk or CD etc..Although having been shown and retouching above Embodiments herein is stated, it is to be understood that above-described embodiment is exemplary, and should not be understood as the limit to the application System, those skilled in the art can be changed above-described embodiment, modify, replace and become within the scope of application Type.

Claims (10)

1. the gammaphoton active position methods of sampling in a kind of scintillation crystal detectors characterized by comprising
The crystal identification that gammaphoton is had an effect is determined according to the output signal of the scintillation crystal detectors;
Obtain the probability distribution of crystals active position corresponding with the crystal identification;
According to the probability distribution of the crystals active position, the position having an effect inside target crystal to gammaphoton It is sampled, to obtain the target effect site that gammaphoton is had an effect inside the target crystal, wherein the target Crystal is corresponding with the crystal identification.
2. the method as described in claim 1, which is characterized in that further include:
Obtain the probability value of each active position in the target crystal;
According to the probability value of each active position, the probability distribution of the crystals active position is pre-established.
3. method according to claim 2, which is characterized in that each active position is general in the acquisition target crystal Rate value, comprising:
It is respectively hung down according to the spatial coordinated information of each active position, the space coordinate of default incidence point and each active position Directly be mapped in the space coordinate of location point on target crystal surface, determine each active position respectively respectively corresponding to gamma Photon incident angle, wherein the location point and the default incidence point are in approximately the same plane;
According to the crystal arrangement of each active position corresponding gammaphoton incident angle and the scintillation crystal detectors Information determines that gammaphoton reaches the path of the scintillator crystal materials passed through at each active position inside the target crystal Length;
Attenuation law and each corresponding path length of the active position according to gammaphoton in scintillator crystal materials, Obtain the probability value of each active position in the target crystal.
4. method according to claim 2, which is characterized in that each active position is general in the acquisition target crystal Rate value, comprising:
Active position sequence in S21, the acquisition target crystal, wherein the active position sequence includes multiple according to suitable The active position of sequence arrangement;
S22, for the current active position in the target crystal, according to the spatial coordinated information of current active position, default The space coordinate of incidence point and current active position are vertically mapped in the space coordinate of the location point on target crystal surface, really Gammaphoton incident angle corresponding to the fixed current location;
S23, according to the crystal arrangement information of the gammaphoton incident angle and the scintillation crystal detectors, determine gamma light Son reaches the path length of the scintillator crystal materials passed through at the current active position inside the target crystal;
S24, the attenuation law according to gammaphoton in scintillator crystal materials and the path length, obtain in the target crystal The probability value of the current active position;
S25, according to the active position sequence, obtain the next active position adjacent with the current active position, and general Next active position repeats the step S22 to S24 as the current active position, until traversal institute State all active positions in active position sequence.
5. the method as described in claim 1, which is characterized in that the probability according to the crystals active position point Cloth is sampled the position that gammaphoton is had an effect inside target crystal, brilliant in the target to obtain gammaphoton The target effect site that internal portion has an effect, comprising:
According to the probability distribution of sampling prescription and the crystals active position, gammaphoton is occurred inside target crystal The position of effect carries out multiple sampling, and obtains multiple target effect sites according to sampling results.
6. gammaphoton active position sampling apparatus in a kind of scintillation crystal detectors characterized by comprising
Determining module, for determining crystal mark that gammaphoton is had an effect according to the output signal of the scintillation crystal detectors Know;
First obtains module, for obtaining the probability distribution of crystals active position corresponding with the crystal identification;
Processing module, for the probability distribution according to the crystals active position, to gammaphoton inside target crystal The position having an effect is sampled, to obtain the interacting goals position that gammaphoton is had an effect inside the target crystal It sets, wherein the target crystal is corresponding with the crystal identification.
7. device as claimed in claim 6, which is characterized in that further include:
Second obtains module, for obtaining the probability value of each active position in the target crystal;
Module is established, for the probability value according to each active position, pre-establishes the probability of the crystals active position Distribution.
8. device as claimed in claim 7, which is characterized in that described second obtains module, is specifically used for:
It is respectively hung down according to the spatial coordinated information of each active position, the space coordinate of default incidence point and each active position Directly be mapped in the space coordinate of location point on target crystal surface, determine each active position respectively respectively corresponding to gamma Photon incident angle, wherein the location point and the default incidence point are in approximately the same plane;
According to the crystal arrangement of each active position corresponding gammaphoton incident angle and the scintillation crystal detectors Information determines that gammaphoton reaches the path of the scintillator crystal materials passed through at each active position inside the target crystal Length;
Attenuation law and each corresponding path length of the active position according to gammaphoton in scintillator crystal materials, Obtain the probability value of each active position in the target crystal.
9. a kind of electronic equipment, which is characterized in that including reason device, memory, communication interface and bus;
The processor, the memory are connected by the bus with the communication interface and complete mutual communication;
The memory stores executable program code;
The processor is run and the executable program by reading the executable program code stored in the memory The corresponding program of code, to make for executing gammaphoton in scintillation crystal detectors as described in any one in claim 1-5 With the position methods of sampling.
10. a kind of storage medium, which is characterized in that for storing application program, the application program is used for the storage medium Gammaphoton active position sampling side in scintillation crystal detectors as described in any one in claim 1-5 is executed at runtime Method.
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