CN109603016A - A kind of medical accelerator dosage rate stabilizing control system - Google Patents
A kind of medical accelerator dosage rate stabilizing control system Download PDFInfo
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- CN109603016A CN109603016A CN201811536371.6A CN201811536371A CN109603016A CN 109603016 A CN109603016 A CN 109603016A CN 201811536371 A CN201811536371 A CN 201811536371A CN 109603016 A CN109603016 A CN 109603016A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N2005/1074—Details of the control system, e.g. user interfaces
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
The invention discloses a kind of medical accelerator dosage rate stabilizing control systems, it is capable of the transformation of real-time dynamic response dosage rate based on the present invention, and the fast and stable output of dosage rate is realized by adjusting, the present invention includes: serial communication circuit, signal filter circuit, signal acquisition circuit, MCU circuit, signal generating circuit and alarm output circuit, to obtain the dosage rate of extraneous host setting through serial communication as preset value, real-time dosage rate numerical value is controlled, pass through the software approach such as digital filtering and pid algorithm, it realizes and the instantaneous adjusting of dosage rate is controlled, guarantee that intergal dose deviation meets the requirements and carries out anticipatory control and avoids toning, the frequency for the synchronization signal that will be exported by change in a certain range, keep real-time dosage rate numerical value equal as far as possible with preset value, hardware configuration of the present invention is simple, on software Easily realize.
Description
Technical field
Present system belongs to the technical field of the electron linear accelerator of medical treatment and industrial irradiation application, and in particular to one
Kind medical accelerator dosage rate stabilizing control system.
Background technique
In the application of middle high energy medical computerized linear accelerator, traditional static treatment to the stability requirement of dosage rate not
It is high.With the development of radiation therapy technology, the Active treatments modes such as radian treatment and intensity modulated therapy are developed by static treatment, it is right
In different doctor formulas, accelerator is required to the variation of dynamic response dosage rate, and is capable of fast and stable dosage rate
Output.The dosage rate fluctuation of existing medical accelerator is larger, cannot meet the needs of new.
Summary of the invention
In view of this, can be realized dosage rate the present invention provides a kind of medical accelerator dosage rate stabilizing control system
Export to fast and stable.
A kind of medical accelerator dosage rate stabilizing control system, including serial communication circuit, signal filter circuit, signal are adopted
Collector, MCU (Microcontroller Unit, micro-control unit) circuit and signal generating circuit；
Wherein, signal filter circuit receives the real-time dose rate signal of the ionisation chamber transmission of medical accelerator and to the signal
After RC (Resistor-Capacitance, resistance-capacitance) filtering, it is sent to signal acquisition circuit；
Signal acquisition circuit carries out Integral Processing to filtered signal and obtains real-time dosage rate Xi, it is then sent to MCU
Circuit；
MCU circuit includes resolver, (Proportion-Integral-Differential, proportional, integral-are micro- by PID
Point) algorithm device and comparator；
Wherein, the resolver operates host with medical accelerator by serial communication circuit and connect, and receives medical acceleration
Device operates the dosage rate preset value Y of host setting and adjusts threshold value e, and dosage rate preset value Y diminution fixed proportion is obtained letter
The reference frequency F of number generation circuit；Then dosage rate preset value Y is transmitted to pid algorithm device, threshold value e and benchmark frequency will be adjusted
Rate F is sent to comparator；
Pid algorithm device is according to the real-time dosage rate X receivediWith dosage rate preset value Y, the frequency A of adjustment signal is calculated,
And A is sent to comparator；
Comparator compares the absolute value of the quotient of the frequency A of the adjustment signal received and reference frequency F with threshold value e is adjusted
Compared with if the accommodation limit value of reference frequency is sent to signal generating circuit greater than e by the absolute value of quotient；Otherwise, then by frequency
Value F+A is sent to signal generating circuit；
The signal generating circuit generates the pulse signal of fixed pulse width according to the frequency that comparator exports, then pulse is believed
Output after differential signal number is converted into the preregulator of medical accelerator, so that control dosage rate stablizes output.
Further, the pid algorithm device includes 2 subtracters, 2 buffers, 2 adders and 3 multipliers,
In, subtracter I receives the Y that the Xi that signal acquisition circuit is sent and resolver are sent, and does subtraction, by operation result Xi-Y
It is sent to multiplier I and is sent to adder II after Xi-Y is multiplied by multiplier with the scale factor K p of setting；Subtracter I also connects
Receive the present dose rate score X that signal acquisition circuit is sentiWith last dosage rate score Xi-1, and subtraction is done, it will be current
The poor △ X of dosage rate score and last dosage rate scorei=Xi-Xi-1It is sent to buffer I and buffer II, buffer I will
△X1、△X2、…△XiIt is sent to adder I and does add operation, and by accumulation result △ X1+△X2+…+△XiIt is sent to multiplication
After accumulation result is multiplied by device II, multiplier II with the integrating factor Ki of setting, it is sent to adder II；Buffer II is by △
X1、△X2、…△XiIt is sent to subtracter II and does subtraction, by the difference △ X of two doses rate deviationi-△Xi-1It is sent to
After deviation difference is multiplied by multiplier III, multiplier III with the differential divisor Kd of setting, it is sent to adder II；Adder II
By Kp* (Xi-Y), Ki* (△ X1+△X2+…+△Xi) and Kd* (△ Xi-△Xi-1) be added after to get arriving adjustment signal
Frequency A.
Further, if the absolute value of the quotient of frequency A and reference frequency F are greater than e, judge the symbol of the frequency A of adjustment signal
It number is positive or negative, if being positive, the upper limit value (F* (1+e)) of reference frequency is sent to signal generating circuit；Otherwise, by base
The lower limit value (F* (1-e)) of quasi- frequency is sent to signal generating circuit.
Further, the control system further includes alarm output circuit；The alarm output circuit is connected with comparator,
When the absolute value of the quotient of frequency A and reference frequency F are greater than e, comparator sends alarm number amount to alarm output circuit, alarms defeated
Circuit carries out warning operation out.
Further, the pulsewidth for the pulse signal that the signal generating circuit generates is 1~200 μ s.
The invention has the following beneficial effects:
1, the present invention is capable of the transformation of real-time dynamic response dosage rate, and is adjusted by PID, realizes the quick steady of dosage rate
Fixed output.
2, in the present invention, pid algorithm device uses subtracter, adder, buffer and multiplier, realizes the wink to dosage rate
When adjust controlled, guarantee that intergal dose deviation meets the requirements and carries out anticipatory control and avoids toning, circuit is simple, on software
It can be achieved.
3, in the present invention, alarm output circuit is simple and effective, notifies whether operator's system is working properly.
4, in the present invention, the signal that circuit signal generation circuit generates is the differential signal of fixed pulse width (1-200us), essence
Degree is high, and anti-interference ability is stronger, can be to avoid extraneous false triggering.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of medical accelerator dosage rate stabilizing control system of the invention.
Fig. 2 is the structural schematic diagram of medical accelerator dosage rate stabilizing control system of the invention.
Fig. 3 is the work flow diagram of medical accelerator dosage rate stabilizing control system of the invention.
Specific embodiment
The present invention will now be described in detail with reference to the accompanying drawings and examples.
The present invention provides a kind of medical accelerator dosage rate stabilizing control system.
As shown in Figure 1, the medical accelerator dosage rate stabilizing control system, comprising: serial communication circuit, signal filtering
Circuit, signal acquisition circuit, MCU circuit, signal generating circuit and alarm output circuit.
Wherein, signal filter circuit receives the incoming real-time dose rate signal of other subsystem ionisation chambers of medical accelerator,
And reduce the interference in space and power grid, filtered signal is sent to signal acquisition circuit；
Signal acquisition circuit analyzes rapidly filtered signal by the completion of high speed fpga chip and obtains real-time dosage rate number
Value XiAfter be sent to MCU circuit；
MCU circuit is mainly made of resolver, pid algorithm device and comparator.Wherein, the resolver of MCU circuit passes through string
Port communications circuit is connect with medical accelerator operation host, receives the dosage rate preset value Y of medical accelerator operation host setting
With adjust threshold value e, and calculate according to dosage rate preset value Y the reference frequency F of signal generating circuit；By dosage rate preset value Y
It is transmitted to pid algorithm device, threshold value e and reference frequency F will be adjusted and be sent to comparator；The real-time dosage rate numerical value X that will be receivedi
It is sent to pid algorithm device；Pid algorithm device is according to the real-time dosage rate numerical value X receivediWith dosage rate preset value Y, adjustment is calculated
The frequency A of signal, and the frequency A of adjustment signal is sent to comparator；Comparator is by the frequency A and base of the adjustment signal received
The absolute value of the quotient of quasi- frequency F is compared with threshold value e is adjusted, and according to the size relation of the absolute value of quotient and e, judges adjustment letter
Number frequency A whether exceed adjust threshold value e: if the absolute value of quotient be not more than e, illustrate frequency A without departing from adjust threshold value e,
Frequency value F+A is then sent to signal generating circuit；Illustrate to exceed if the absolute value of quotient is greater than e, exports alarm number
It measures to alarm output circuit, meanwhile, if the frequency A symbol of adjustment signal is positive, upper limit value (F* (1+e)) is sent to signal
Generation circuit；If the frequency A symbol of adjustment signal is negative, lower limit value (F* (1-e)) is sent to signal generating circuit.
The signal generating circuit generates the pulse signal of fixed pulse width (1~200 μ s) according to the frequency that comparator exports,
The stronger differential signal of anti-interference ability is converted as extraneous synchronization signal for pulse signal again to export to medical accelerator
Preregulator, thus control dosage rate stablize output.
The alarm output circuit carries out warning operation according to the alarm number amount that comparator exports, and notifies extraneous this system
Exceed and has adjusted threshold value.
Meanwhile dosage rate state of a control is sent to medical accelerator operation host through resolver by comparator.
Wherein, pid algorithm implement body composition is as shown in Fig. 2, include 2 subtracters, 2 buffers, 2 adders and 3
A multiplier, wherein subtracter I receives the Y that the Xi that signal acquisition circuit is sent and resolver are sent, and does subtraction, will
Operation result Xi-Y is sent to multiplier I and is sent to adder after Xi-Y is multiplied by multiplier with the scale factor K p of setting
II；Subtracter I also receives the present dose rate score X of signal acquisition circuit transmissioniWith last dosage rate score Xi-1, and do
Subtraction, by the poor △ X of present dose rate score and last dosage rate scorei=Xi-Xi-1It is sent to buffer I and buffering
Device II, buffer I are by △ X1、△X2、…△XiIt is sent to adder I and does add operation, and by accumulation result △ X1+△X2+…+
△XiIt is sent to multiplier II and is sent to adder II after accumulation result is multiplied by multiplier II with the integrating factor Ki of setting；
Buffer II is by △ X1、△X2、…△XiIt is sent to subtracter II and does subtraction, by the difference △ X of two doses rate deviationi-
△Xi-1It is sent to multiplier III and is sent to adder after deviation difference is multiplied by multiplier III with the differential divisor Kd of setting
II；Adder II is by Kp* (Xi-Y), Ki* (△ X1+△X2+…+△Xi) and Kd* (△ Xi-△Xi-1) be added after to get
To the frequency A of adjustment signal.Thus, it is possible to can calculate and obtain by simple subtracter, adder, buffer and multiplier
The frequency A of the adjustment signal of PID control is obtained, circuit is simple, Yi Shixian.
As shown in figure 3, the workflow of this method are as follows:
Step 1, setting dosage rate and adjusting threshold value e: setting dosage rate and adjusting on the operation host of medical accelerator
The dosage rate score of needs and adjusting threshold value e are sent to by the operation host of threshold value e, medical accelerator by serial communication circuit
The control system of accelerator, control system parse it, obtain respective value；
Step 2, synchronization signal exports: the dosage rate of setting is reduced fixed proportion and obtains signal generating circuit by control system
Reference frequency F, signal generating circuit generates the pulse signal of fixed pulse width according to reference frequency F, and pulse signal converted
It exports to be not easy the differential signal being disturbed as the synchronization signal of medical accelerator preregulator to preregulator；
Step 3, dosage rate detects: preregulator receives the output of control radiation from machine dosage after synchronization signal, accelerates
The ionisation chamber detection dose of radiation of device is simultaneously sent to signal filter circuit, the radiation that signal filter circuit transmits ionisation chamber
After dose signal is filtered, it is transmitted to signal acquisition circuit, signal acquisition circuit calculates dose of radiation in real time
MCU circuit is sent to, to obtain real-time dosage rate values Xi；
Step 4, compare adjustment: control system calculates the difference of real-time dosage rate numerical value and setting dosage rate, if difference exists
In allowable range of error, then do not change the frequency of synchronization signal, maintains output.If difference exceeds allowable range of error, adjust same
The frequency for walking signal, obtains new synchronization signal, enters step 5；The PID that is adjusted to of the frequency of synchronization signal is adjusted, specifically
It is as follows:
By the dosage rate Y of setting and real-time dosage rate XiSubtraction is carried out, by poor (Y-Xi) multiplied by the scale factor of setting
Kp realizes scale operation；By difference (Y-X each time1, Y-X2, Y-X3..., Y-Xi) progress summation operation obtains and Si, by Si
Integral operation is realized multiplied by the integrating factor Ki of setting；By current dose rates XiWith a preceding dosage rate Xi-1Subtraction is carried out,
By poor (Xi-Xi-1) differentiate multiplied by the differential divisor Kd realization of setting；The result summation of operation obtains synchronization signal three times
Frequency adjusted value A, F+A be new synchronous signal frequency value.
Step 5, judge overshoot: judging whether the quotient of new synchronous signal frequency value and reference frequency F exceeds [1-e, 1+e]
Interval range；If without departing from, by current synchronization signal export to medical accelerator preregulator otherwise, then circuit carry out
Alarm notifies external circuitry overshoot, while defeated as synchronization signal using the limiting value F* (1+e) of reference frequency F or F* (1-e)
Out to the preregulator of medical accelerator, guarantee the output of synchronization signal, if the quotient of new synchronous signal frequency value and reference frequency F
Less than 1-e, then the reference frequency limiting value as synchronization signal output is F* (1-e), if new synchronous signal frequency value and base
The quotient of quasi- frequency F is greater than 1+e, then the reference frequency limiting value as synchronization signal output is F* (1+e).
In conclusion the above is merely preferred embodiments of the present invention, being not intended to limit the scope of the present invention.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (5)
1. a kind of medical accelerator dosage rate stabilizing control system, which is characterized in that including serial communication circuit, signal filtered electrical
Road, signal acquisition circuit, MCU circuit and signal generating circuit；
Wherein, signal filter circuit receives the real-time dose rate signal of the ionisation chamber transmission of medical accelerator and filters to signal RC
After wave, it is sent to signal acquisition circuit；
Signal acquisition circuit carries out Integral Processing to filtered signal and obtains real-time dosage rate Xi, is then sent to MCU circuit；
MCU circuit includes resolver, pid algorithm device and comparator；
Wherein, the resolver operates host with medical accelerator by serial communication circuit and connect, and receives medical accelerator behaviour
The dosage rate preset value Y and adjusting threshold value e of hosted setting, and dosage rate preset value Y diminution fixed proportion is obtained into signal and is produced
The reference frequency F of raw circuit；Then dosage rate preset value Y is transmitted to pid algorithm device, threshold value e and reference frequency F will be adjusted and sent out
It send to comparator；
Pid algorithm device calculates the frequency A of adjustment signal according to the real-time dosage rate Xi and dosage rate preset value Y received, and will
A is sent to comparator；
The absolute value of the quotient of the frequency A of the adjustment signal received and reference frequency F is compared by comparator with threshold value e is adjusted,
If the absolute value of quotient is greater than e, the accommodation limit value of reference frequency is sent to signal generating circuit；Otherwise, then by frequency value F
+ A is sent to signal generating circuit；The signal generating circuit is believed according to the pulse that the frequency that comparator exports generates fixed pulse width
Number, then export after converting differential signal for pulse signal to the preregulator of medical accelerator, to control the stabilization of dosage rate
Output.
2. a kind of medical accelerator dosage rate stabilizing control system as described in claim 1, which is characterized in that the PID is calculated
Musical instruments used in a Buddhist or Taoist mass includes 2 subtracters, 2 buffers, 2 adders and 3 multipliers, wherein subtracter I receives signal acquisition circuit
Operation result Xi-Y is sent to multiplier I by the Y that the Xi and resolver of transmission are sent, and do subtraction, and multiplier is by Xi-Y
After being multiplied with the scale factor K p of setting, it is sent to adder II；Subtracter I also receives the current agent of signal acquisition circuit transmission
Dose rate numerical value XiWith last dosage rate score Xi-1, and subtraction is done, by present dose rate score and last dosage rate number
The poor △ X of valuei=Xi-Xi-1It is sent to buffer I and buffer II, buffer I is by △ X1、△X2、…△XiIt is sent to adder
I does add operation, and by accumulation result △ X1+△X2+…+△XiBe sent to multiplier II, multiplier II by accumulation result with set
After fixed integrating factor Ki is multiplied, it is sent to adder II；Buffer II is by △ X1、△X2、…△XiSubtracter II is sent to do
Subtraction, by the difference △ X of two doses rate deviationi-△Xi-1It is sent to multiplier III, multiplier III is by deviation difference
After being multiplied with the differential divisor Kd of setting, it is sent to adder II；Adder II is by Kp* (Xi-Y), Ki* (△ X1+△X2+…+
△Xi) and Kd* (△ Xi-△Xi-1) be added after to get arrive adjustment signal frequency A.
3. a kind of medical accelerator dosage rate stabilizing control system as described in claim 1, which is characterized in that if frequency A and
The absolute value of the quotient of reference frequency F is greater than e, judges that the symbol of the frequency A of adjustment signal is positive or bears, if being positive, by base
The upper limit value (F* (1+e)) of quasi- frequency is sent to signal generating circuit；Otherwise, the lower limit value of reference frequency (F* (1-e)) is sent out
It send to signal generating circuit.
4. a kind of medical accelerator dosage rate stabilizing control system as described in claim 1, which is characterized in that the control system
System further includes alarm output circuit；The alarm output circuit is connected with comparator, when frequency A and reference frequency F quotient it is exhausted
E is greater than to value, comparator sends alarm number amount to alarm output circuit, and alarm output circuit carries out warning operation.
5. a kind of medical accelerator dosage rate stabilizing control system as described in claim 1, which is characterized in that the signal produces
The pulsewidth for the pulse signal that raw circuit generates is 1~200 μ s.
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| CN201811536371.6A CN109603016A (en) | 2018-12-14 | 2018-12-14 | A kind of medical accelerator dosage rate stabilizing control system |
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| CN201811536371.6A CN109603016A (en) | 2018-12-14 | 2018-12-14 | A kind of medical accelerator dosage rate stabilizing control system |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101797423A (en) * | 2010-04-12 | 2010-08-11 | 江苏海明医疗器械有限公司 | Self-correcting multi-cure-fitting digital dosage monitoring method and system |
| CN206442575U (en) * | 2016-12-26 | 2017-08-25 | 江苏海明医疗器械有限公司 | A kind of medical accelerator close rate stabilization control circuit |
| CN108124373A (en) * | 2017-12-18 | 2018-06-05 | 合肥中科离子医学技术装备有限公司 | A kind of devices and methods therefor for being used to control superconducting cyclotron accelerating potential |
| US20180270941A1 (en) * | 2014-02-27 | 2018-09-20 | ETM Electromatic, Inc. | Linear accelerator system for stable pulsing at multiple dose levels |
-
2018
- 2018-12-14 CN CN201811536371.6A patent/CN109603016A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101797423A (en) * | 2010-04-12 | 2010-08-11 | 江苏海明医疗器械有限公司 | Self-correcting multi-cure-fitting digital dosage monitoring method and system |
| US20180270941A1 (en) * | 2014-02-27 | 2018-09-20 | ETM Electromatic, Inc. | Linear accelerator system for stable pulsing at multiple dose levels |
| CN206442575U (en) * | 2016-12-26 | 2017-08-25 | 江苏海明医疗器械有限公司 | A kind of medical accelerator close rate stabilization control circuit |
| CN108124373A (en) * | 2017-12-18 | 2018-06-05 | 合肥中科离子医学技术装备有限公司 | A kind of devices and methods therefor for being used to control superconducting cyclotron accelerating potential |
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Application publication date: 20190412 |