CN109549631A - A kind of Multifunctional LED light source for skin fluorescence detection - Google Patents
A kind of Multifunctional LED light source for skin fluorescence detection Download PDFInfo
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- CN109549631A CN109549631A CN201811522996.7A CN201811522996A CN109549631A CN 109549631 A CN109549631 A CN 109549631A CN 201811522996 A CN201811522996 A CN 201811522996A CN 109549631 A CN109549631 A CN 109549631A
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- led light
- base body
- annular base
- light source
- ultraviolet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The present invention provides a kind of Multifunctional LED light source for skin fluorescence detection, including the LED light that annular base body and annular base body lower surface are fixed, the annular base body top has eyeshade, the annular base body lower part has hood, convex lens sheet and ultraviolet filter are from top to bottom successively embedded in the annular base body, handle is fixedly connected on rear side of the annular base body, have in the handle for providing the battery of the energy, the LED light is uniformly distributed along annular base body upper surface, and LED light includes ultraviolet source and white light source.The present invention passes through above technical scheme, solve due to conventional ultra-violet exciting light have a single function cause it is inefficient and inconvenient in fluorescence detection, the clinical application range for increasing ultraviolet source, facilitates doctor and directly passes through fluorescence phenomenon using the LED light of the device and intuitively diagnose the illness and instruct optical dynamic therapy.
Description
Technical field
The present invention relates to a kind of Multifunctional LED light sources for skin fluorescence detection.
Background technique
Contain the endogenous fluorescence color group there are many different component in normal and abnormal skin tissue, in specific wavelength ultraviolet light spoke
It penetrates under excitation, characterized fluorescence can be generated in the tissue.It is special to observe the position of this kind of specificity fluorescent and color in skin histology
The characters such as point have critically important clinical meaning to cutaneous lesions are identified.For some infectious diseases, since certain pathogen can
To generate characterized fluorescence substance, the specificity fluorescent of different colours can produce under the irradiation of ultraviolet light.In addition to endogenous fluorescence,
Excite external source fluorescence, such as the detection of photosensitizer fluorescence, to the visualization of the distribution of photosensitizer, to light power diagnosis, to instructing light
Dynamic therapy has many clinical values.But the burst of ultraviolel light source that dermatologist uses both at home and abroad at present is mostly traditional 5
Moral lamp, the central wavelength of the black light tube used is near 360 nm.The ultraviolet radioactive function of the wood's lamp of more fluorescent tubes composition
Rate is low and uneven, causes its function and application scene single, has been unable to satisfy dermatologist and has carried out the fine of skin fluorescence
The demand of the endogenous and external source iridescent group of different component in observation and accurate recording tissue.
Summary of the invention
The present invention improves the above problem, i.e., the technical problem to be solved by the present invention is to existing more light tube groups
At wood's lamp Radiant UV Power it is low and uneven, cause its function and clinical application range single, be unable to satisfy skin
The fine and accurate observation of skin section doctor progress skin fluorescence.
Specific embodiments of the present invention are: a kind of Multifunctional LED light source for skin fluorescence detection, including annular seating
The LED light that body and annular base body lower surface are fixed, the annular base body top have eyeshade, and the annular base body lower part, which has, to be hidden
Light shield, is from top to bottom successively embedded with convex lens sheet and ultraviolet filter in the annular base body, fixed on rear side of the annular base body
It is connected with handle, is had in the handle for providing the battery of the energy, the LED light is along the uniform cloth in annular base body upper surface
And if LED light includes ultraviolet source and white light source.
Further, the ultraviolet source is 16 high brightness ultraviolet LEDs, and central wavelength is respectively 365 nm and 400
Nm, the white light source are 8 high-brightness white-light LEDs, colour temperature 6500K.
Further, the optical filter is long pass filter piece, and cutoff wavelength is 420 nm, and the optical filter is outside one
In screw thread snap ring, the annular base body lower end has the internal screw thread being threadedly engaged with external screw thread snap ring.
Further, the ultraviolet filter disc is in an external screw thread snap ring, and the annular base body lower end has and external screw thread
The internal screw thread that snap ring is threadedly engaged.
Further, the hood is up-small and down-big conical black soft rubber, and the upper surface of hood has magnetic
Property, the eyeshade is that lower surface has magnetism, the annular base body lower surface and lower end surface have can respectively with eyeshade and shading
Cover the magnet to attract each other.
Further, it is fixedly connected with mobile phone clamping device on the handle, the mobile phone clamping device includes and handle
The fixed link being fixedly connected, the fixed link have the grip block for clamping mobile phone, the grip block towards the side of eyeshade
The upper convex block with for limiting mobile phone.
Further, the handle is embedded with control chip, and described control chip one end is connect with LED light, on rear side of handle
With control LED lamplight opening and closing switch, control ultraviolet LED luminous intensity the first knob and for controlling white light LEDs brightness
The second knob.
Further, the control electrical chip uses AT89C51 chip, and the AT89C51 chip is connected with circuit by counting
The analog signal of input is converted to number by mode converter, display screen, 12M crystal oscillator, rheostat, capacitor, resistance, digital analog converter
Signal is exported to 12M crystal oscillator provides working frequency for AT89C51 chip, controls 51 cores by the first knob standardsizing rheostat R3
Piece exports PWM frequency, controls ultraviolet LED luminous intensity, adjusts white light LEDs brightness by the second knob standardsizing rheostat R4.
Further, two groups totally 16 ultraviolet LED lamps the connection type connection of mixed connection in parallel after first series connection is respectively adopted,
Every 4 ultraviolet LEDs are a unit, are divided into Unit two, the ultraviolet LED in every unit is first connected, between two homochromy units again
Using series connection;
Every 4 white light LEDs are a unit, are divided into Unit two;Corresponding white light LEDs are first connected in every unit, are adopted again between every group
With series connection;Finally, each ultraviolet LED part and white light LEDs part in parallel.
Compared with prior art, the invention has the following advantages: the present invention is by above technical scheme, solve by
Having a single function in conventional ultra-violet exciting light causes inefficient and inconvenient in fluorescence detection, increases the clinical application model of ultraviolet source
It encloses, facilitates doctor and directly pass through fluorescence phenomenon using the LED light of the device and intuitively diagnose the illness and instruct optical dynamic therapy.
Detailed description of the invention
Fig. 1 is decomposition texture schematic diagram of the present invention.
Fig. 2 is LED lamp structure schematic diagram of the present invention.
Fig. 3 is side structure schematic view of the present invention.
Fig. 4 is chip embodiment attachment structure schematic diagram of the present invention.
Specific embodiment
The present invention will be further described in detail with reference to the accompanying drawings and detailed description.
As shown in figures 1-4, a kind of Multifunctional LED light source for skin fluorescence detection, including annular base body 10 and annular
The fixed LED light 20 in 10 lower surface of pedestal, the annular base body top have eyeshade 30, and the annular base body lower part has shading
Cover 40, is from top to bottom successively embedded with convex lens sheet 110 and ultraviolet filter 120 in the annular base body, after the annular base body
Side is fixedly connected with handle 50.
Having in the handle for providing the battery of the energy, the LED light is uniformly distributed along annular base body upper surface, and
LED light includes ultraviolet source and white light source.
The optical filter and the ultraviolet filter disc are respectively embedded in an external screw thread snap ring 60, and 10 lower end of annular base body has
The internal screw thread 130 cooperated respectively with two external screw thread snap rings 60 at two.
In the present embodiment, the optical filter is long pass filter piece, and cutoff wavelength is 420 nm, described in the present embodiment
External screw thread snap ring internal diameter is a 86 mm common-use sizes for selecting camera optical filter.Convex lens sheet diameter phi=86 mm, it is ultraviolet
Filter disc diameter phi=86 mm.
In the present embodiment, the hood 40 be up-small and down-big conical black soft rubber, conical black soft rubber,
There is certain scalability, is suitable for adjusting light source and skin distance, and effectively block the interference of indoor light.
In the present embodiment, the upper surface of hood 40 has magnetism, and the eyeshade 30 is that lower surface has magnetism, round black
Color soft rubber can effectively block the interference of indoor light, and observation is carried out cosily convenient for observer's eyes.
Magnetism is generated in the present embodiment can add magnetic powder during fabrication, can also by the upper surface of hood 40 and
30 lower surface fixed permanent magnet of eyeshade, 10 lower surface of annular base body and lower end surface have can respectively with eyeshade and hood phase
The magnet mutually attracted, magnet 140 described in the present embodiment are annular.
Realize that carrying out record to the skin condition embodied in hood takes pictures in order to improve, it is fixed on the handle to connect
It is connected to mobile phone clamping device, the mobile phone clamping device includes the fixed link 60 being fixedly connected with handle, the fixed link direction
The side of eyeshade has the grip block 70 for clamping mobile phone, has the convex block 710 for limiting mobile phone on the grip block, can
The adjustment of clamping mobile phone is realized in grip block 70 by bolted splice.
In the present embodiment, the ultraviolet source be 16 high brightness ultraviolet LEDs, central wavelength be respectively 365 nm and
400 nm, the white light source are 8 high-brightness white-light LEDs, colour temperature 6500K.
In the present embodiment, two groups of connection types that mixed connection in parallel after first series connection is respectively adopted in totally 16 ultraviolet LED lamps connect
It connects, every 4 ultraviolet LEDs are a unit, are divided into Unit two, the ultraviolet LED in every unit is first connected, between two homochromy units
Again using series connection;
Every 4 white light LEDs are a unit, are divided into Unit two;White light LEDs in every unit are first connected, again using string between every group
Connection connection;Finally, each ultraviolet LED part and white light LEDs part in parallel.
The handle 50 is embedded with control chip, and described control chip one end is connect with LED light, has control on rear side of handle
The switch 810 of LED lamplight opening and closing controls the first knob 820 of ultraviolet LED luminous intensity and for controlling white light LEDs brightness
Second knob 830.There are the sags and crests for increasing and rubbing on first knob and the second knob surface.
In the present embodiment, the circuit control part is to use the tune of PWM using 51 single-chip microcontrollers as the control circuit of core
Light mode controls the output power of LED, adjusts white light LEDs brightness and ultraviolet LED luminous intensity.
In the present embodiment, the handle 50 is also devised with cutting for the independent white light LEDs illumination of switching or purple LED pattern switching
Change key 840.
In the present embodiment, the control electrical chip use AT89C51 chip, the AT89C51 chip be connected with circuit by
Digital analog converter ADC0832, display screen 1602,12M crystal oscillator, rheostat, capacitor, resistance, digital analog converter ADC0832 will be inputted
Analog signal be converted to digital signal and export to AT89C51,12M crystal oscillator provides working frequency for AT89C51, passes through the first rotation
Button standardsizing rheostat R3 controls 51 chips and exports PWM frequency, controls ultraviolet LED radiation intensity, adjusts variable resistance by the second knob
Device R4 adjusts white light LEDs brightness.
It is hollow for disposing three section 3.7v lithium batteries in handle in the present embodiment, it is high generally having a size of 19 mm of diameter
Spend 66 mm.It is equipped with lithium battery dedicated charger, which is total power switch, directly controls three groups of light source switch, root when illumination
According to needing to switch two groups of difference ultraviolet sources.
In use, hood can be mounted below annular base body when doctor needs lesion region fluorescence phenomenon, starting
Switch annular LED lamp lights.
If ultraviolet LED lamp may be selected to shine, the first knob is adjusted to control burst of ultraviolel luminous intensity, to obtain suitable fluorescence
Intensity adjusts the second knob to control white brightness, to obtain suitable light source and brightness as needed.Doctor's glasses pass through eye
Fluorescence phenomenon in cover observation annular base body, ultraviolet filter disc can remove the interference of uv excitation light, and hood can stop ambient light
Interference, the image that convex lens can amplify lesion region facilitate doctor observe lesion details, when doctor need to observe skin it is normal
When form under light, hood can be accepted, the first knob uv excitation light is adjusted to minimum brightness, is adjusted by the second knob white
Light LED is observed to suitable brightness, when doctor need other wavelength it is ultraviolet when, pressing mode selection button can switch separately
One group of ultraviolet wavelength.
When needing to obtain the normal image and fluorescent image of lesion region with camera, mobile phone can be limited in handset bracket
On, so that mobile lens focusing, which in target area, then switchs adjusting ultraviolet LED brightness and white light LEDs brightness respectively, to be obtained
Take the fluorogram and white light figure under corresponding conditions.
The present invention is solved by above technical scheme since conventional ultra-violet exciting light (such as black light wood's lamp) has a single function
Caused by trouble in fluorescence detection, increase the clinical application range of ultraviolet source.Doctor is facilitated to examine by fluorescence phenomenon
Disconnected some diseases.
Any technical solution disclosed in aforementioned present invention unless otherwise stated, if it discloses numberical range,
Disclosed numberical range is preferred numberical range, and any it should be appreciated by those skilled in the art preferred numberical ranges
The only obvious or representative numerical value of technical effect in many enforceable numerical value.It, can not since numerical value is more
Exhaustion, so the present invention just discloses technical solution of the component values to illustrate the present invention, also, the above-mentioned numerical value enumerated is not
The limitation to the invention protection scope should be constituted.
If the words such as " first ", " second " are used herein come if limiting components, those skilled in the art are answered
This knows: the use of " first ", " second " is intended merely to facilitate in description and is distinguished components as not having Stated otherwise
Outside, above-mentioned word has no special meaning.
Meanwhile if aforementioned present invention discloses or relates to the components or structural member of connection fastened to each other, except another
There is statement outer, is fixedly connected it is to be understood that connection (such as using bolt or screw connection) can be removedly fixed, it can also
To understand are as follows: non-removable to be fixedly connected with (such as riveting, welding), certainly, connection fastened to each other or integral type knot
Structure (such as manufacturing using casting technique is integrally formed) is replaced (obviously can not be using except integrally formed technique).
In addition, for indicating the art of positional relationship or shape applied in any technical solution disclosed in aforementioned present invention
Its meaning includes approximate with its, similar or close state or shape to language unless otherwise stated.
Either component provided by the invention by multiple individual component parts either assembled, or one
The separate part that forming technology manufactures.
Finally it should be noted that: the above embodiments are merely illustrative of the technical scheme of the present invention and are not intended to be limiting thereof;To the greatest extent
The present invention is described in detail with reference to preferred embodiments for pipe, it should be understood by those ordinary skilled in the art that: still
It can modify to a specific embodiment of the invention or some technical features can be equivalently replaced;Without departing from this hair
The spirit of bright technical solution should all cover within the scope of the technical scheme claimed by the invention.
Claims (9)
1. a kind of Multifunctional LED light source for skin fluorescence detection, which is characterized in that including under annular base body and annular base body
The fixed LED light in surface, the annular base body top have eyeshade, and the annular base body lower part has hood, the annular
It is from top to bottom successively embedded with convex lens sheet and ultraviolet filter in pedestal, is fixedly connected with handle on rear side of the annular base body, institute
Stating in handle has for providing the battery of the energy, and the LED light is uniformly distributed along annular base body upper surface, and LED light includes
Ultraviolet source and white light source.
2. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 1, which is characterized in that described
Ultraviolet source is 16 high brightness ultraviolet LEDs, and central wavelength is respectively 365 nm and 400 nm, and the white light source is 8
High-brightness white-light LED, colour temperature 6500K.
3. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 1 or 2, which is characterized in that institute
Stating optical filter is long pass filter piece, and cutoff wavelength is 420 nm, and the optical filter is in an external screw thread snap ring, the annular
Pedestal lower end has the internal screw thread being threadedly engaged with external screw thread snap ring.
4. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 1 or 2, which is characterized in that institute
Ultraviolet filter disc is stated in an external screw thread snap ring, the annular base body lower end has the interior spiral shell being threadedly engaged with external screw thread snap ring
Line.
5. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 2, which is characterized in that described
Hood is up-small and down-big conical black soft rubber, and the upper surface of hood has magnetism, and the eyeshade is following table mask
It is magnetic, the annular base body lower surface and lower end surface have the magnet that can be attracted each other respectively with eyeshade and hood.
6. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 1 or 2, which is characterized in that institute
It states and is fixedly connected with mobile phone clamping device on handle, the mobile phone clamping device includes the fixed link being fixedly connected with handle, institute
Stating fixed link has grip block for clamping mobile phone towards the side of eyeshade, has on the grip block for limiting mobile phone
Convex block.
7. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 2, which is characterized in that described
Handle is embedded with control chip, and described control chip one end is connect with LED light, has control LED lamplight opening and closing on rear side of handle
Switch, the first knob of control ultraviolet LED luminous intensity and the second knob for controlling white light LEDs brightness.
8. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 7, which is characterized in that described
It controls electrical chip and uses AT89C51 chip, it is brilliant by digital analog converter, display screen, 12M that the AT89C51 chip is connected with circuit
The analog signal of input is converted to digital signal and exported by vibration, rheostat, capacitor, resistance, digital analog converter, and 12M crystal oscillator is
AT89C51 chip provides working frequency, controls 51 chips by the first knob standardsizing rheostat R3 and exports PWM frequency, control is purple
Outer LED luminous intensity adjusts white light LEDs brightness by the second knob standardsizing rheostat R4.
9. a kind of Multifunctional LED light source for skin fluorescence detection according to claim 2, which is characterized in that two groups
The connection type connection of mixed connection in parallel after first series connection is respectively adopted in totally 16 ultraviolet LED lamps, and every 4 ultraviolet LEDs are a unit,
It is divided into Unit two, the ultraviolet LED in every unit is first connected, again using series connection between two homochromy units;
Every 4 white light LEDs are a unit, are divided into Unit two;Corresponding white light LEDs are first connected in every unit, are adopted again between every group
With series connection;Finally, each ultraviolet LED part and white light LEDs part in parallel.
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CN201811522996.7A CN109549631A (en) | 2018-12-13 | 2018-12-13 | A kind of Multifunctional LED light source for skin fluorescence detection |
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CN201811522996.7A CN109549631A (en) | 2018-12-13 | 2018-12-13 | A kind of Multifunctional LED light source for skin fluorescence detection |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112120671A (en) * | 2020-09-22 | 2020-12-25 | 上海中医药大学附属岳阳中西医结合医院 | Multifunctional hand-held skin examination instrument |
CN113749771A (en) * | 2021-04-30 | 2021-12-07 | 上海格联医疗科技有限公司 | Molecular image near-infrared two-zone fluorescence navigation system |
CN113892022A (en) * | 2019-05-27 | 2022-01-04 | 株式会社日立高新技术 | Light source and biochemical analyzer |
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