CN109512412A - A kind of central aortic blood pressure measuring device - Google Patents
A kind of central aortic blood pressure measuring device Download PDFInfo
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- CN109512412A CN109512412A CN201811391840.XA CN201811391840A CN109512412A CN 109512412 A CN109512412 A CN 109512412A CN 201811391840 A CN201811391840 A CN 201811391840A CN 109512412 A CN109512412 A CN 109512412A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
- A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
Abstract
The invention discloses a kind of central aortic blood pressure measuring device, including brachial arterial pressure measurement, electrocardio measurement, radial artery blood pressure measurement, data processing, pulse wave translation time assessment, the assessment of pulse wave reflection coefficient, central aortic pressure calculates and the modules such as data are shown；Pulse wave translation time evaluation module is for finding out pulse wave translation time；Pulse wave is divided into incidence wave and back wave by pulse wave reflection coefficient evaluation module, is calculated the ratio of the sum of reflex amplitude and incidence wave and reflex amplitude, is obtained pulse wave reflection coefficient；Central aortic pressure computing module calibrates radial artery blood corrugating；Simultaneously by pulse wave translation time and pulse wave reflection coefficient inputting mathematical model, transmission function is calculated, then calculates central aortic corrugating using the radial artery blood corrugating after the transmission function and calibration.The present invention can improve the measurement accuracy of central aortic pressure significantly, reduce measurement error.
Description
Technical field
The present invention relates to blood pressure detectings, and in particular to a kind of to realize the noninvasive center aortic blood of individuation using peripheral arterial
The device for pressing measurement, belongs to the field of medical instrument technology.
Background technique
Central aortic pressure refers to root of ascending aorta blood pressure, and systolic pressure represents the afterload of heart, with left ventricular hypertrophy phase
It closing, diastolic pressure is then perfusion pressure coronarius, while affecting brain, kidney and lung et al. weight and wanting organ dysfunction, so with
The relationship of cardiovascular disease is very close.In recent years, being constantly progressive with central aortic pressure non-invasive measurement technology, people's centering
The research of pulse pressure aroused in interest focuses more on and gos deep into, and has gradually been used in antihypertensive drugs selection and the clinical observation of curative effect.One
It is a little research shows that: central aortic pressure is more prominent compared to the clinical value and directive significance of brachial arterial pressure, dynamic compared to the periphery upper arm
Arteries and veins blood pressure can more reflect cardiac load, more closely related with the generation of cardiovascular event.In recent years, central aortic blood pressure obtains
Medical profession is more and more paid attention to, the hypertension management guidance hand of European hypertension association and the joint publication of heart of Europe disease association
Volume is using central aortic pressure as the important indicator of blood pressure management.The comparative study of some Treatment of Hypertension shows: in difference
Antihypertensive drugs reduce in the similar situation of peripheral blood pressure degree, reducing the degree of central aortic pressure, but there may be larger differences
It is different, monitoring with reduce central aortic pressure and compare peripheral arterial to be pressed in meaning in Treatment of Hypertension bigger.Therefore, the standard of central aortic pressure
Really measurement cardiovascular disease detection and in terms of it is very crucial, with important clinical significance.
Currently, the device and method of measuring center angiosthenia is divided into invasive and noninvasive two major classes.
Invasive device and method is to be inserted into conduit from peripheral arterial using intervening equipment, such as radial artery and femoral artery,
Catheter end head is extend at aorta ascendens, is then measured, this method is measuring center angiosthenia " goldstandard ".It is invasive
Method is mainly used for the fields such as first aid, cardiovascular interventional operation and Intensive Care Therapy, but this method has invasive and complicated for operation, institute
Clinically to have certain limitation.
Noninvasive device and method mainly pass through using pressure sensor or inflation cuff in sensor acquisition radial artery,
Arteria carotis or brachial arterial pressure signal, then founding mathematical models analyze and diagnose data, and measurement obtains central aortic
Blood pressure.
(1) Japanese Omron Ke Lin company develops HEM9000AI central arterial pressure detector, which passes through high-fidelity
Pressure probe obtains radial artery pulse wave automatically, and analyze obtain the pulse wave the second systolic blood pressure, using the systolic pressure as
Primary variables calculates central aortic pressure by specific regression model.But major defect existing for the device and method is
The accurate positioning of the second peak of pulse wave is more difficult, leads to not the central aortic pressure for measuring part sufferer.
(2) AtCorMedical company, Australia develops SphygmoCor arterial pulse wave analysis system, the instrument
It pops one's head in by high-fidelity, radial artery pulse wave is obtained by surface pressing method by hand, the general transfer function method as obtained by statistics
It calculates and obtains central aortic blood pressure waveform, calculate central aortic pressure after recycling arteria brachialis mean arterial pressure and diastolic pressure correction.
Although the accuracy of these central aortic blood pressure measuring methods based on general transfer function method is tested in some documents
Card, but primary limitation existing for the instrument is cannot to modify transmission function with varying with each individual, and there are certain deviations, especially special
Anisotropic crowd, such as hypertension, artery sclerosis sufferer.
(3) Singapore DiaTecne company develops BPro survey meter of blood pressure, which adopts also with pressure sensor
The pulse wave of radial artery or arteria carotis is obtained with pressing tensammetry, and the arteria brachialis measured using cuff is to radial artery or to human body
Radial artery blood corrugating carries out Multipoint movable average treatment and obtains human body central aortic blood pressure waveform.Although the device and method obtain
To the verifying of clinical test to a certain extent, but there are the following problems: the Multipoint movable method of average comes from clinical experience, multiple spot
Value can not adaptively be modified for different users, so the method in the device is similarly universal method, Bu Nengpai
Except the individuation difference bring of individual cardiovascular function influences.
In conclusion the major defect of existing non-invasive central arterial pressure measuring device does not account for human body artery parameter
Otherness, to cause measurement error.
Summary of the invention
The problem that difference between sufferer causes central aortic pressure measurement error larger cannot be embodied for existing measuring device, this
The purpose of invention is to propose a kind of new central aortic pressure measuring device, difference of this measuring device in view of human body artery parameter
The opposite sex realizes the measurement of personalization centre angiosthenia, can significantly improve the measurement accuracy of central aortic pressure.
The technical scheme of the present invention is realized as follows:
A kind of central aortic blood pressure measuring device, it is characterised in that: surveyed including data acquisition and control module, brachial arterial pressure
Measure module, electrocardio measurement module, radial artery blood pressure measurement module, data processing module, pulse wave translation time evaluation module, arteries and veins
It fights wave reflection coefficient evaluation module, central aortic pressure computing module and data disaply moudle；
Data acquisition and control module connects brachial arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement mould
Block controls starting and stopping for brachial arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement module respectively, and
The measurement data of brachial arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement module is exported to data processing
Module；
The measurement data that brachial arterial pressure measurement module passes over is handled and is calculated by data processing module
Arteria brachialis systolic pressure, diastolic pressure or mean pressure are simultaneously exported to central aortic pressure computing module；Data processing module measures electrocardio
The measurement data that module passes over is handled to obtain electrocardiosignal and be exported to pulse wave translation time evaluation module sum number
According to display module；Data processing module is handled the measurement data that radial artery blood pressure measurement module passes over to obtain oar and be moved
Arteries and veins blood pressure signal is simultaneously exported respectively to pulse wave translation time evaluation module, pulse wave reflection coefficient evaluation module and central aortic
Press computing module；
Pulse wave translation time evaluation module receives the electrocardiosignal and radial artery blood pressure that data processing module is sent
Signal, completes the positioning of electrocardiosignal characteristic point, and completes the positioning of radial artery blood pressure signal wave foot point, passes through two anchor points
The corresponding time, the difference of the two is found out, pulse wave translation time PTT is passed to center by as pulse wave translation time PTT
Angiosthenia computing module；
Pulse wave reflection coefficient evaluation module receives the radial artery blood pressure signal that data processing module is sent, and carries out
Pulse wave is divided into incidence wave and back wave, calculates reflex amplitude and the sum of incidence wave and reflex amplitude by normalized
Ratio, obtain pulse wave reflection R, pulse wave reflection R passed into central aortic pressure computing module；
Central aortic pressure computing module is using arteria brachialis systolic pressure, diastolic pressure or the mean pressure received to radial artery blood pressure
Waveform is calibrated；Simultaneously by the pulse wave translation time PTT received and pulse wave reflection R inputting mathematical model,
Transmission function is calculated, then calculates central aortic pressure wave using the radial artery blood corrugating after the transmission function and calibration
Shape, and radial artery blood corrugating, central aortic corrugating and the basic parameter after calibration are exported to data disaply moudle；
Electrocardiosignal that data disaply moudle sends over the electrocardio measurement module received, central aortic pressure calculate mould
Radial artery blood corrugating, central aortic corrugating and basic parameter after the calibration of block output are shown that basic parameter includes
Arteria brachialis systolic pressure, diastolic pressure, mean pressure and heart rate.
The brachial arterial pressure measurement module by cuff, gas circuit conduit, baroceptor and inflation/deflation motor form,
In, cuff is connect with gas circuit conduit, and gas circuit conduit is connect with charge and discharge Pneumatic generator, charge and discharge Pneumatic generator by gas circuit conduit to cuff into
Row inflation/deflation, baroceptor are used to monitor the air pressure change in cuff or gas circuit, and the output of baroceptor connects data processing
Module is calculated systolic pressure, diastolic pressure and the mean pressure of arteria brachialis by data processing module.
The electrocardio measurement module is made of two electrode patch, two line conductors and electrocardiogram signal processing circuit, wherein two
Electrode patch is used to acquire the myoelectric potential of different location at body surface two, wherein being all the way reference potential, two line conductors believe electrocardio
It number is transmitted to electrocardiogram signal processing circuit, the processing that electrocardiogram signal processing circuit completes electrocardiosignal simultaneously completes two paths of signals phase
Subtract, subtracted signal is then passed into data processing module.
The radial artery blood pressure measurement module is made of piezoelectric transducer, conducting wire and blood pressure signal processing circuit, wherein pressure
Electric transducer obtains the fluctuating signal of radial artery, and gives signal to blood pressure signal processing circuit, blood pressure signal by wire transmission
Processing circuit completes the processing such as filtering and amplification of blood pressure signal, and signal passes to data processing module by treated.
The pulse wave translation time PTT is calculated as follows,
PTT=T2-T1
Wherein, T2Time, T are corresponded to normalize the wave foot point of radial artery wave1It is corresponding for the R wave or S wave of electrocardiosignal
Time.
The pulse wave reflection R calculation formula is as follows,
Pf=(Pr+Z0·I)/2
Pb=(Pr-Z0·I)/2
R=| Pb|/(|Pf|+|Pb|)
Wherein, PfAnd PbFor forward and backward blood pressure wave, PrIt is radial artery blood pressure and blood flow wave, Z with I0For radial artery feature
Impedance.
In the central aortic pressure computing module, the mathematical model for the transmission function being shown below is established:
Wherein, ω and i represent angular frequency and imaginary part；
Fourier transformation is carried out to the radial artery blood corrugating after calibration, the frequency after obtaining radial artery blood pressure Fourier transformation
Compose Pr(ω) utilizes the radial artery blood pressure signal spectrum P obtained after transmission function and Fourier transformationr(ω) can be counted as the following formula
Calculate the frequency spectrum of central aortic blood pressure signal:
Central aortic corrugating finally can be obtained using inverse Fourier transform, to complete the survey of central aortic blood pressure
Amount.
Compared with the prior device, the present invention calculates central aortic pressure using new mathematical model, it is contemplated that different people is moved
The pulse wave translation time of vein system system and the otherness of pulse wave reflection coefficient, the artery for increasing embodiment different people based on this are poor
The measurement module of Anisotropic parameter, and the otherness is used to calculate different human transmission functions, realize personalization centre angiosthenia
Measurement.The present invention can improve the measurement accuracy of central aortic pressure significantly, reduce measurement error, measure so as to basis
Central blood pressure waveform accurately obtain the information of a large amount of cardiovascular systems, the Health Status of Cardiovascular System of person under test is accurately divided
Analysis.
Detailed description of the invention
The structural block diagram of Fig. 1-central blood pressure measuring device provided by the invention.
The estimation schematic diagram of Fig. 2-pulse wave translation time assessment provided by the invention.
Fig. 3-pulse wave reflection coefficient appraisal procedure schematic diagram provided by the invention.
The general step of Fig. 4-central blood pressure waveform measurement provided by the invention.
Specific embodiment
The present invention is described in further detail with reference to the accompanying drawings and examples, however, the present invention is not limited thereto.
Measuring device of the present invention is moved by data acquisition and control module, brachial arterial pressure measurement module, electrocardio measurement module, oar
Arteries and veins blood pressure measurement module, data processing module, pulse wave translation time evaluation module, pulse wave reflection coefficient evaluation module, in
The composition such as pulse pressure computing module aroused in interest, data disaply moudle, the structural block diagram of the central aortic pressure measuring device are as shown in Figure 1.
Data acquisition and control module controls other modules and carries out proceeding measurement and processing, including brachial arterial pressure measurement module
Starting and terminate control and cuff inflation/deflation control, electrocardiosignal measurement control, radial artery blood pressure measurement module data
Acquisition, and the data for controlling these three modules are exported to data processing module.
Brachial arterial pressure measurement module is by cuff, gas circuit conduit, baroceptor, charge and discharge Pneumatic generator and arteria brachialis signal
Reason is formed with computing module, wherein cuff is connect with gas circuit conduit, and gas circuit conduit and baroceptor and charge and discharge Pneumatic generator connect
It connects, charge and discharge Pneumatic generator carries out inflation/deflation to cuff by gas circuit conduit, and baroceptor monitors the air pressure in cuff or gas circuit and becomes
Change, the output of baroceptor connects data processing module, calculates arteria brachialis systolic pressure, diastolic pressure peace by data processing module
Press.
Electrocardio measurement module is made of two electrode patch, two line conductors and electrocardiogram signal processing circuit, wherein two electrodes
Patch is used to acquire the myoelectric potential of different location at body surface two, wherein being all the way reference potential, two line conductors pass electrocardiosignal
Transport to electrocardiogram signal processing circuit, electrocardiogram signal processing circuit completes the processing of electrocardiosignal and complete two paths of signals to subtract each other, so
Subtracted signal is passed into data processing module afterwards.
Radial artery blood pressure measurement module is made of piezoelectric transducer, a line conductor and blood pressure signal processing circuit, wherein pressure
Electric transducer obtains the fluctuating signal of radial artery, and gives signal to blood pressure signal processing circuit by wire transmission, and the circuit is complete
The processing such as filtering and amplification at blood pressure signal, and signal passes to data processing module by treated.
Data processing module: realizing the collection and pretreatment of each module data, and sends the data to specified module and carry out
It is further processed and analyzes.Arteria brachialis signal is handled and is calculated, then by arteria brachialis systolic pressure and diastolic pressure export to
Central aortic pressure computing module；Electrocardiosignal is handled, electrocardiosignal to pulse wave translation time all the way is then exported and comments
Estimate module and data disaply moudle；The output of radial artery blood pressure measurement module all the way comment to pulse wave translation time respectively by blood pressure signal
Estimate module, pulse wave reflection coefficient evaluation module and central aortic pressure computing module.
Pulse wave translation time evaluation module: the module receives the electrocardiosignal and radial artery blood pressure letter of data processing module
Number, the positioning of electrocardiosignal characteristic point (such as T wave, Q wave) is completed, and complete the positioning of radial artery blood pressure signal wave foot point, passed through
Two anchor points corresponding time finds out the difference of the two, as pulse wave translation time.By the conduction time pass in it is aroused in interest
Pulse pressure computing module.
Pulse wave reflection coefficient evaluation module: the module receives the radial artery blood pressure signal of data processing module, and carries out
Normalized calculates reflex amplitude and incidence wave and reflex amplitude by the way that pulse wave is divided into incidence wave and back wave
The sum of ratio, obtain reflection coefficient.The reflection coefficient is passed into central aortic pressure computing module.
Central aortic pressure computing module receives parameter (the arteria brachialis systolic pressure, diastolic pressure that data processing module passes over
And mean pressure), radial artery blood corrugating, pulse wave translation time and pulse wave reflection coefficient；Using arteria brachialis systolic pressure, relax
It opens pressure or radial artery blood corrugating is calibrated in mean pressure；Then pulse wave translation time and reflection coefficient input are established
Mathematical model in, calculate personalized delivery function；Then the radial artery blood corrugating meter after transmission function and calibration is utilized
Calculate central aortic corrugating.And (such as oar is dynamic by radial artery blood corrugating, central aortic corrugating and the basic parameter after calibration
Arteries and veins and central reduction pressure, mean pressure, diastolic pressure, heart rate etc.) it exports to data disaply moudle.
Data disaply moudle: the module receives the electrocardiosignal of electrocardio measurement module, the output of central aortic pressure computing module
Calibration after radial artery blood corrugating, central aortic corrugating and basic parameter it is (such as radial artery and central reduction pressure, average
Pressure, diastolic pressure, heart rate etc.), these waveforms and parameter are presented to display screen, check measurement result for user.
In the pulse wave translation time evaluation module, the schematic diagram calculation of conduction time PTT as shown in Fig. 2,
Calculation formula such as formula (1).
PTT=T2-T1 (1)
Wherein, T2Wave foot point (characteristic point 2) corresponding time to normalize radial artery wave, T1For the R wave of electrocardiosignal
Or S wave (characteristic point 1) the corresponding time.System is once it is determined that or all with R wave or all with S wave, cannot be used in mixed way.
In the pulse wave reflection coefficient evaluation module, the assessment of reflection R is as described in Figure 3, calculation formula
Such as formula (2).
Pf=(Pr+Z0·I)/2 (2)
Pb=(Pr-Z0·I)/2 (3)
R=| Pb|/(|Pf|+|Pb|) (4)
Wherein, PfAnd PbFor forward and backward blood pressure wave, PrIt is radial artery blood pressure and blood flow wave, Z with I0For radial artery feature
Impedance.
In the central aortic pressure computing module, the mathematical model of transmission function as shown in Equation 5 is established:
Wherein, ω and i represent angular frequency and imaginary part.
Fourier transformation is carried out to the radial artery blood corrugating after calibration, the frequency after obtaining radial artery blood pressure Fourier transformation
Compose Pr(ω) utilizes the radial artery blood pressure signal spectrum P after transmission function and Fourier transformationr(ω) can be calculated as the following formula
The frequency spectrum of central aortic blood pressure signal:
Central aortic corrugating finally can be obtained using inverse Fourier transform, to complete the survey of central aortic blood pressure
Amount.
The specific steps of central aortic pressure measurement method in data processing module are divided into modelling phase and in real time prison
The survey stage.
The specifically used method of this measuring device is as follows, referring also to Fig. 4:
Step 1: tester lies low, rest after five minutes, starts by data acquisition and control module and controls brachial arterial pressure
Air pressure in measurement module in the inflation/deflation speed and cuff of air pump, completes the measurement of brachial arterial pressure；
Step 2: starting and controlling electrocardio measurement module and radial artery blood pressure measurement mould by data acquisition and control module
Block completes the synchro measure of electrocardiosignal and radial artery blood pressure signal；
Step 3: log-on data processing module, electrocardio is inputted to it, blood pressure signal data are denoised, go drift, normalizing
The relevant treatments such as change and calibration；
Step 4: starting pulse wave translation time evaluation module and pulse wave reflection coefficient evaluation module, complete pulse wave
The calculating of conduction time and reflection coefficient；
Step 5: starting central aortic pressure computing module, completes pulse wave translation time and reflection coefficient construction transmitting letter
The building of several data models, and the radial artery blood pressure signal after calibration is combined to calculate central aortic blood pressure waveform；
Step 6: electrocardiosignal and blood pressure waveform and relevant parameter are shown on a display screen, while generating examining report.
Finally, it should be noted that the above embodiment of the present invention is only example to illustrate the invention, and it is not
It is the restriction to embodiment of the present invention.For those of ordinary skill in the art, on the basis of the above description also
Other various forms of variations and variation can be made.Here all embodiments can not be exhaustive.It is all to belong to this
The technical solution changes and variations that derived from of invention are still in the scope of protection of the present invention.
Claims (7)
1. a kind of central aortic blood pressure measuring device, it is characterised in that: measured including data acquisition and control module, brachial arterial pressure
Module, electrocardio measurement module, radial artery blood pressure measurement module, data processing module, pulse wave translation time evaluation module, pulse
Wave reflection coefficient evaluation module, central aortic pressure computing module and data disaply moudle；
Data acquisition and control module connects brachial arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement module, point
Not Kong Zhi brachial arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement module start and stop, and by the upper arm
The measurement data of arterial pressure measurement module, electrocardio measurement module and radial artery blood pressure measurement module is exported to data processing mould
Block；
The measurement data that brachial arterial pressure measurement module passes over is carried out processing and the upper arm is calculated moves by data processing module
Arteries and veins systolic pressure, diastolic pressure or mean pressure are simultaneously exported to central aortic pressure computing module；Data processing module is by electrocardio measurement module
The measurement data passed over is handled to obtain electrocardiosignal and be exported aobvious to pulse wave translation time evaluation module and data
Show module；Data processing module is handled the measurement data that radial artery blood pressure measurement module passes over to obtain radial artery blood
Pressure signal is simultaneously exported respectively to pulse wave translation time evaluation module, pulse wave reflection coefficient evaluation module and central aortic pressure meter
Calculate module；
Pulse wave translation time evaluation module receives the electrocardiosignal and radial artery blood pressure signal that data processing module is sent,
The positioning of electrocardiosignal characteristic point is completed, and completes the positioning of radial artery blood pressure signal wave foot point, it is corresponding by two anchor points
Time, the difference both found out, pulse wave translation time PTT passes to central aortic by as pulse wave translation time PTT
Press computing module；
Pulse wave reflection coefficient evaluation module receives the radial artery blood pressure signal that data processing module is sent, and carries out normalizing
Pulse wave is divided into incidence wave and back wave, calculates the ratio of the sum of reflex amplitude and incidence wave and reflex amplitude by change processing
Value, obtains pulse wave reflection R, pulse wave reflection R is passed to central aortic pressure computing module；
Central aortic pressure computing module is using arteria brachialis systolic pressure, diastolic pressure or the mean pressure received to radial artery blood corrugating
It is calibrated；Simultaneously by the pulse wave translation time PTT received and pulse wave reflection R inputting mathematical model, calculate
Then transmission function out calculates central aortic corrugating using the radial artery blood corrugating after the transmission function and calibration, and
Radial artery blood corrugating, central aortic corrugating and basic parameter after calibration is exported to data disaply moudle；
Electrocardiosignal that data disaply moudle sends over the electrocardio measurement module received, central aortic pressure computing module are defeated
Radial artery blood corrugating, central aortic corrugating and basic parameter after calibration out are shown that basic parameter includes that the upper arm is dynamic
Arteries and veins systolic pressure, diastolic pressure, mean pressure and heart rate.
2. central aortic blood pressure measuring device according to claim 1, it is characterised in that: the brachial arterial pressure measures mould
Block is by cuff, gas circuit conduit, baroceptor and inflation/deflation motor form, wherein cuff is connect with gas circuit conduit, gas circuit conduit
It is connect with charge and discharge Pneumatic generator, charge and discharge Pneumatic generator carries out inflation/deflation to cuff by gas circuit conduit, and baroceptor is for monitoring sleeve
Air pressure change in band or gas circuit, the output of baroceptor connect data processing module, calculate the upper arm by data processing module and move
Systolic pressure, diastolic pressure and the mean pressure of arteries and veins.
3. central aortic blood pressure measuring device according to claim 1, it is characterised in that: the electrocardio measurement module is by two
A electrode patch, two line conductors and electrocardiogram signal processing circuit are constituted, wherein two electrode patch are different at body surface two for acquiring
The myoelectric potential of position, wherein being all the way reference potential, electrocardiosignal is transmitted to electrocardiogram signal processing circuit, electrocardio by two line conductors
Signal processing circuit completes the processing of electrocardiosignal and completes two paths of signals and subtract each other, and subtracted signal is then passed to data processing
Module.
4. central aortic blood pressure measuring device according to claim 1, it is characterised in that: the radial artery blood pressure measurement mould
Block is made of piezoelectric transducer, conducting wire and blood pressure signal processing circuit, wherein piezoelectric transducer obtains the pulsation letter of radial artery
Number, and signal is given to blood pressure signal processing circuit by wire transmission, blood pressure signal processing circuit completes the filtering of blood pressure signal
It, and will treated that signal passes to data processing module with the processing such as amplification.
5. central aortic blood pressure measuring device according to claim 1, it is characterised in that: the pulse wave translation time
PTT is calculated as follows,
PTT=T2-T1
Wherein, T2Time, T are corresponded to normalize the wave foot point of radial artery wave1For electrocardiosignal R wave or corresponding S wave when
Between.
6. central aortic blood pressure measuring device according to claim 1, it is characterised in that: the pulse wave reflection R
Calculation formula is as follows,
Pf=(Pr+Z0·I)/2
Pb=(Pr-Z0·I)/2
R=| Pb|/(|Pf|+|Pb|)
Wherein, PfAnd PbFor forward and backward blood pressure wave, PrIt is radial artery blood pressure and blood flow wave, Z with I0For radial artery characteristic impedance.
7. central aortic blood pressure measuring device according to claim 1, it is characterised in that: calculated in the central aortic pressure
In module, the mathematical model for the transmission function being shown below is established:
Wherein, ω and i represent angular frequency and imaginary part；
Fourier transformation is carried out to the radial artery blood corrugating after calibration, the frequency spectrum P after obtaining radial artery blood pressure Fourier transformationr
(ω) utilizes the radial artery blood pressure signal spectrum P obtained after transmission function and Fourier transformationr(ω) can be calculated as the following formula
The frequency spectrum of central aortic blood pressure signal out:
Central aortic corrugating finally can be obtained using inverse Fourier transform, to complete the measurement of central aortic blood pressure.
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| CN111493855A (en) * | 2020-04-21 | 2020-08-07 | 重庆理工大学 | System and method for non-invasive measurement of individualized cardiac output |
| CN111839717A (en) * | 2020-07-27 | 2020-10-30 | 哈尔滨医科大学 | System for real-time display of trans-aortic valve pressure in room interval ablation |
| CN112790748A (en) * | 2020-12-30 | 2021-05-14 | 重庆理工大学 | Central arterial pressure waveform reconstruction system and method |
| CN113076705A (en) * | 2021-03-26 | 2021-07-06 | 北京阅影科技有限公司 | Method and device for simulating blood flow dynamics |
| CN113143230A (en) * | 2021-05-11 | 2021-07-23 | 重庆理工大学 | Peripheral arterial blood pressure waveform reconstruction system |
| CN113499048A (en) * | 2021-07-22 | 2021-10-15 | 重庆理工大学 | Central arterial pressure waveform reconstruction system and method based on CNN-BilSTM |
| CN115990007A (en) * | 2022-11-30 | 2023-04-21 | 未来穿戴健康科技股份有限公司 | Central artery pressure waveform fitting method, monitoring device and watch equipment |
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| CN111493855A (en) * | 2020-04-21 | 2020-08-07 | 重庆理工大学 | System and method for non-invasive measurement of individualized cardiac output |
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| CN112790748A (en) * | 2020-12-30 | 2021-05-14 | 重庆理工大学 | Central arterial pressure waveform reconstruction system and method |
| CN113076705A (en) * | 2021-03-26 | 2021-07-06 | 北京阅影科技有限公司 | Method and device for simulating blood flow dynamics |
| CN113143230A (en) * | 2021-05-11 | 2021-07-23 | 重庆理工大学 | Peripheral arterial blood pressure waveform reconstruction system |
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| CN113499048B (en) * | 2021-07-22 | 2022-07-08 | 重庆理工大学 | Central arterial pressure waveform reconstruction system and method based on CNN-BilSTM |
| CN115990007A (en) * | 2022-11-30 | 2023-04-21 | 未来穿戴健康科技股份有限公司 | Central artery pressure waveform fitting method, monitoring device and watch equipment |
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