CN109501255A - A kind of production method using 3D printing technique production materials for use in skull-fixing - Google Patents

A kind of production method using 3D printing technique production materials for use in skull-fixing Download PDF

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Publication number
CN109501255A
CN109501255A CN201811448676.1A CN201811448676A CN109501255A CN 109501255 A CN109501255 A CN 109501255A CN 201811448676 A CN201811448676 A CN 201811448676A CN 109501255 A CN109501255 A CN 109501255A
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Prior art keywords
skull
printing
processing
cleaned
ultraviolet light
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CN201811448676.1A
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Chinese (zh)
Inventor
孟兵
卢媚媛
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Individual
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Priority to CN201811448676.1A priority Critical patent/CN109501255A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20Apparatus for additive manufacturing; Details thereof or accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2875Skull or cranium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C18/00Disintegrating by knives or other cutting or tearing members which chop material into fragments
    • B02C18/06Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives
    • B02C18/08Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers
    • B02C18/12Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers with drive arranged below container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10Processes of additive manufacturing
    • B29C64/106Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/124Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00Apparatus for additive manufacturing; Details thereof or accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]

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  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Optics & Photonics (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Food Science & Technology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention discloses a kind of production methods using 3D printing technique production materials for use in skull-fixing, before the use, first obtain patient's skull CT images data, the processing such as modeled by professional software in computer and carry out data modification, it is copied in 3D printer after processing, exposure module is according to set data to glass window emitting ultraviolet light, elevating mechanism is slowly slided upwards during irradiation, to drive substrate to be moved, substrate irradiated by ultraviolet light during movable after resin storage tank inside resin solidified in the bottom of substrate, resin without being irradiated by ultraviolet light keeps the state of liquid, after printed, printing skull model is taken out manually to be cleaned, the post-processing such as polishing, printing skull model is cleaned after processing, disinfection, packaging, printing skull model exists It manually cleaned, polished etc. after post-processings, being placed in sterilized space in solidification 20-30 minutes.

Description

A kind of production method using 3D printing technique production materials for use in skull-fixing
Technical field
It is specially a kind of to make materials for use in skull-fixing using 3D printing technique the present invention relates to increases material manufacturing technology field Production method.
Background technique
When intracranial hypertension occur in craniocerebral trauma, cerebral hemorrhage, consistent both at home and abroad at present all to use decompressive craniectomy, purpose is just It is that the brain tissue of swelling is allowed to have volume expansions to release stress, the skull of removal can also release certain space, to reach It depressurizes purpose, but artificial causes " skull defeci ".
In the nearly traffic accident in 10 years in China, craniocerebral injury accounts for the 2nd in all kinds of wounds, incidence 22- 42%, about 600,000 person-times every year, it is more than dead 100,000 people;868.7 people of cranial vascular disease illness rate/100,000 populations, acute stage The death rate has 50%, and skull defect repair material, which generallys use titanium net, at present (will do two-dimensional design, three-dimensional process, computer moulding Deng), titanium poor biocompatibility, disadvantage is more, and now best materials for use in skull-fixing is PEEK material, but expensive.
After removing bone flap decompression operation, usually needs to carry out cranioplasty surgery again after 3-6 months, (need secondary cranium Repairing bone operation), cranioplasty surgery traumatic larger and surgery cost is higher again again.
Summary of the invention
The purpose of the present invention is to provide the production methods using 3D printing technique production materials for use in skull-fixing, on solving State the problem of proposing in background technique.
To achieve the above object, the invention provides the following technical scheme: a kind of make skull repairing using 3D printing technique The production method of material, including cup body, elevating mechanism and resin storage tank, including following three steps;
Step 1: it is described before use, first obtain patient's skull CT images data, by professional software in computer carry out modeling and into The processing such as row data modification, copies it in 3D printer to after processing, exposure module is according to set data to windowpane Mouth emitting ultraviolet light, elevating mechanism is slowly slided upwards during irradiation, so that substrate is driven to be moved, substrate The resin inside resin storage tank after being irradiated during movable by ultraviolet light is solidified in the bottom of substrate, without quilt The resin that ultraviolet light is irradiated keeps the state of liquid, after printed, take out printing skull model and is manually cleaned, polished Post-processing is cleaned printing skull model after processing, is sterilized, is packed;
Step 2: it is described patient's cranial bone flap is removed after, by simple process, be put into the inside of cup body, device connects power supply The surface for pressing motor cabinet afterwards is provided with switch, motor shaft is fixedly installed at the top of motor cabinet, the surface of motor shaft is driven to fix Blade is installed to be rotated, the cranial bone flap of patient is crushed to realize, and be ground into the particle of 1-2 square;
Step 3: the bone particle by crushing stirs evenly together with the blending of a certain proportion of biogum, after mixing evenly will The bone particle that biogum mixes pours into printing skull model, after pouring into half, strikes off, at this point, placing supporting network ruling, puts Remaining bone particle is poured into after good until arriving contour edge height, strikes off, molding bone particle bone flap is solidified after striking off, Bone particle bone flap is taken out after solidification plants back patient's encephalic.
Further, the printing skull model is placed on sterilized space after the post-processings such as manually being cleaned, being polished Inherence solidification 20-30 minutes.
Further, lid is fixedly installed at the top of the cup body, and the side of cup body is fixedly installed with handle.
Further, the operation consent printing skull model is carried out in normal room, and finished product will pass through strict sterilization, nothing Bacterium bag dress, for use, whole process needs 60-90 minutes or so.
Further, step 2 with step 3 is carried out in operating room, and whole process all operates under aseptic conditions, operation Time is about 15-20 minutes.
Compared with prior art, the beneficial effects of the present invention are: this utilizes 3D printing technique production materials for use in skull-fixing Production method, when in use can be to the mistake that patient's cranial bone flap is crushed by being fixedly installed with lid at the top of cup body Cheng Zhong avoids the broken body of patient's cranial bone flap from flying out from the inside of device, so that the practicability of device is improved, and by cup body Side is fixedly installed with handle, can be more convenient user of service when in use and move to device, improve the practicability of device With portability, and by with step 3 being carried out in operating room in step 2, whole process all operates under aseptic conditions, behaviour It is about 15-20 minutes as the time, so as to avoid secondary cranioplasty surgery, reduces the wound of cranioplasty surgery again, Surgery cost again has been saved, has driven the surface of motor shaft to be fixedly mounted by being fixedly installed with motor shaft at the top of motor cabinet There is blade to be rotated, the cranial bone flap of patient is crushed to realize, by placing branch between printing skull model Grid lines is supportted, can effectively increase the stability of printing skull model entirety, to keep device more secured.
Detailed description of the invention
Fig. 1 is skull pulverizer figure of the invention;
Fig. 2 is 3D printing skull simulator structure chart of the invention;
Fig. 3 is 3D printing skull simulator structure chart of the invention;
Fig. 4 is the technical solution flow chart that 3D printing technique substep of the invention makes materials for use in skull-fixing.
In figure: 1, cup body;2, blade;3, motor cabinet;4, lid;5, handle;6, motor shaft;7, it switchs;8, substrate;9, purple Outer light;10, exposure module;11, it rises mechanism;12, resin;13, resin storage tank;14, glass window;15, skull model is printed.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that term " on ", "lower", "inner", "outside" " front end ", " rear end ", The orientation or positional relationship of the instructions such as " both ends ", " one end ", " other end " is to be based on the orientation or positional relationship shown in the drawings, only It is that for the convenience of describing the present invention and simplifying the description, rather than the device or element of indication or suggestion meaning must have specifically Orientation is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.In addition, term " first ", " the Two " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation " " is set Be equipped with ", " connection " etc., shall be understood in a broad sense, such as " connection ", may be a fixed connection, may be a detachable connection or one Connect to body;It can be mechanical connection, be also possible to be electrically connected;It can be directly connected, it can also be indirect by intermediary It is connected, can be the connection inside two elements.For the ordinary skill in the art, on being understood with concrete condition State the concrete meaning of term in the present invention.
Embodiment provided by the invention: a kind of production method using 3D printing technique production materials for use in skull-fixing, including Cup body 1, elevating mechanism 11 and resin storage tank 13, including following three steps;
Step 1: it before use, first obtaining patient's skull CT images data, is modeled and is counted by professional software in computer According to the processing such as repairing, it is copied in DLP3D printer using mobile hard disk after processing, exposure module 10 is according to set Data are to 14 emitting ultraviolet light 9 of glass window, and elevating mechanism 11 to rise 50-100 micron height every time during irradiation It is slowly slided upwards, so that substrate 8 be driven to be moved, after substrate 8 is irradiated by ultraviolet light 9 during movable Resin 12 inside resin storage tank 13 is solidified in the bottom of substrate 8, projector project again formed a section, this section with Upper section bonding, moves in circles, the skull model to be made is ultimately formed, then remove from base station, without ultraviolet The resin 12 that light 9 is irradiated keeps the state of liquid, after printed, printing skull model 15 is manually cleaned after taking-up, The post-processing such as polishing is cleaned printing skull model 15 after processing, is sterilized, is packed;
Step 2: after patient's cranial bone flap is removed, by simple process, it is put into the inside of cup body 1, is pressed after device connection power supply The surface of lower motor cabinet 3 is provided with switch 7, and the whole of device is powered, and the top of motor cabinet 3 is fixedly installed with the drive of motor shaft 6 The surface of motor shaft 6 is fixedly installed with blade 2 and is rotated, and crushes to realize to the cranial bone flap of patient, and crush At the particle of 1-2mm square, it is then turned off power supply;
Step 3: the bone particle of crushing and the blending of a certain proportion of biogum are manually stirred uniformly together, stirred evenly The bone particle that biogum mixes is poured into printing skull model 15 afterwards, after pouring into half, the tool using profession is micro- to bone The surface of grain is struck off, at this point, placing supporting network ruling, remaining bone particle is poured into after putting well until high to contour edge Degree strikes off the surface of bone particle using the tool of profession, solidifies after striking off to molding bone particle bone flap, solidifies Bone particle bone flap is taken out afterwards plants back patient's encephalic.
Further, printing skull model 15 is placed in sterilized space after the post-processings such as manually being cleaned, being polished In solidification 20-30 minutes, to make to print more firm after skull model 15 forms.
Further, the top of cup body 1 is fixedly installed with lid 4, during being crushed to patient's cranial bone flap, The broken body of patient's cranial bone flap is avoided to fly out from the inside of device, to improve the practicability of device, and the fixed peace in side of cup body 1 Equipped with handle 5, user of service can be more convenient, device is moved, improve the practicability and portability of device.
Further, operation consent printing skull model 15 is carried out in normal room, and finished product will pass through strict sterilization, sterile Packaging, for use, whole process needs 60-90 minutes or so, to guarantee that device is constantly in sterile state, avoid by Bacterium infection.
Further, step 2 with step 3 is carried out in operating room, and whole process all operates under aseptic conditions, operation Time is about 15-20 minutes, so as to avoid secondary cranioplasty surgery, reduces the wound of cranioplasty surgery again, section About surgery cost again.
A kind of production method using 3D printing technique production materials for use in skull-fixing, skull pulverizer includes cup body 1, motor Seat 3 and lid 4, the surface of motor cabinet 3 are provided with switch 7, and the top of motor cabinet 3 is fixedly installed with motor shaft 6, motor shaft 6 Surface is fixedly installed with blade 2, and cup body 1, the fixed peace in the top of cup body 1 are fixedly installed at the top of the motor cabinet 3 of 6 periphery of motor shaft Equipped with lid 4;
3D printing skull simulator includes exposure module 10, elevating mechanism 11 and resin storage tank 13, it is characterised in that: exposure module 10 upper end is fixedly installed with glass window 14, and the upper end of glass window 14 is fixedly installed with resin storage tank 13, and resin storage tank 13 It is internally provided with resin 12, the side of resin storage tank 13 is fixedly installed with elevating mechanism 11, the resin storage tank 13 of 11 side of elevating mechanism Top is fixedly installed with substrate 8, and the lower end of substrate 8 is fixedly installed with printing skull model 15.
It summarizes:
This patent is used to be directed to cranium brain by devising a kind of production method for making materials for use in skull-fixing using 3D printing technique When wound or cranial vascular disease cause the patient of intracranial hypertension to carry out bone flap decompression operation, patient's cranium for will being removed in operation Bone bone flap pass through this programme make skeletonization particle bone flap and plant back patient's encephalic with mitigate patient need second operation pain and Reduce the high price surgery cost generated with other operation plans.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.

Claims (5)

1. it is a kind of using 3D printing technique production materials for use in skull-fixing production method, including cup body (1), elevating mechanism (11) and Resin storage tank (13), it is characterised in that: including following three steps;
Step 1: it is described before use, first obtain patient's skull CT images data, by professional software in computer carry out modeling and into The processing such as row data modification, copies it in 3D printer to after processing, exposure module (10) is according to set data to glass Glass window (14) emitting ultraviolet light (9), elevating mechanism (11) is slowly slided upwards during irradiation, to drive base Plate (8) is moved, substrate (8) irradiated by ultraviolet light (9) during movable after resin storage tank (13) inside resin (12) it being solidified in the bottom of substrate (8), the resin (12) without being irradiated by ultraviolet light (9) keeps the state of liquid, After printed, the post-processings such as taking-up printing skull model (15) is manually cleaned, polished, to printing skull model after processing (15) it cleaned, sterilized, packed;
Step 2: it is described patient's cranial bone flap is removed after, by simple process, be put into the inside of cup body (1), device connection electricity The surface that motor cabinet (3) is pressed behind source is provided with switch (7), and motor shaft (6) are fixedly installed at the top of motor cabinet (3) and drive electricity The surface of arbor (6) is fixedly installed with blade (2) and is rotated, and crushes to realize to the cranial bone flap of patient, and powder It is broken into 1-2(mm) particle of square;
Step 3: the bone particle by crushing stirs evenly together with the blending of a certain proportion of biogum, after mixing evenly will The bone particle that biogum mixes pours into printing skull model (15), after pouring into half, strikes off, at this point, placing protection support lattice Line pours into remaining bone particle until striking off to contour edge height, carries out after striking off to molding bone particle bone flap after putting well Solidification takes out bone particle bone flap and plants back patient's encephalic after solidification.
2. a kind of production method using 3D printing technique production materials for use in skull-fixing according to claim 1, feature Be: the printing skull model (15) is placed in sterilized space after the post-processings such as manually being cleaned, being polished solid Change 20-30 minutes.
3. a kind of production method using 3D printing technique production materials for use in skull-fixing according to claim 1, feature It is: is fixedly installed with lid (4) at the top of the cup body (1), and the side of cup body (1) is fixedly installed with handle (5).
4. a kind of production method using 3D printing technique production materials for use in skull-fixing according to claim 1, feature Be: operation consent printing skull model (15) carries out in normal room, and finished product will pass through strict sterilization, no bacterium bag Dress, for use, whole process needs 60-90 minutes or so.
5. a kind of production method using 3D printing technique production materials for use in skull-fixing according to claim 1, feature Be: step 2 with step 3 is carried out in operating room, and whole process all operates under aseptic conditions, and the operating time is about 15-20 minutes.
CN201811448676.1A 2018-11-30 2018-11-30 A kind of production method using 3D printing technique production materials for use in skull-fixing Withdrawn CN109501255A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111227931A (en) * 2020-01-08 2020-06-05 西安马克医疗科技有限公司 3D model construction method and preparation method for aortic valve diseases
CN111227930A (en) * 2020-01-08 2020-06-05 西安马克医疗科技有限公司 3D model construction and preparation method for mitral regurgitation and calcified stenosis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105536049A (en) * 2016-01-18 2016-05-04 西北工业大学 Preparation method of fixed-point qualitative medicament-encapsulated artificial bone bracket
CN106847040A (en) * 2017-03-03 2017-06-13 宁波维迈医疗科技有限公司 Human body organa parenchymatosum's model preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105536049A (en) * 2016-01-18 2016-05-04 西北工业大学 Preparation method of fixed-point qualitative medicament-encapsulated artificial bone bracket
CN106847040A (en) * 2017-03-03 2017-06-13 宁波维迈医疗科技有限公司 Human body organa parenchymatosum's model preparation method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111227931A (en) * 2020-01-08 2020-06-05 西安马克医疗科技有限公司 3D model construction method and preparation method for aortic valve diseases
CN111227930A (en) * 2020-01-08 2020-06-05 西安马克医疗科技有限公司 3D model construction and preparation method for mitral regurgitation and calcified stenosis

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Application publication date: 20190322