CN109479876A - Suspending agent and preparation method thereof - Google Patents
Suspending agent and preparation method thereof Download PDFInfo
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- CN109479876A CN109479876A CN201811198738.8A CN201811198738A CN109479876A CN 109479876 A CN109479876 A CN 109479876A CN 201811198738 A CN201811198738 A CN 201811198738A CN 109479876 A CN109479876 A CN 109479876A
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- agent
- suspending agent
- emamectin benzoate
- suspending
- solubilizer
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/28—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group; Thio analogues thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/30—Derivatives containing the group >N—CO—N aryl or >N—CS—N—aryl
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
Abstract
The invention belongs to technical field of pesticide, and in particular to a kind of suspending agent and preparation method thereof.It is in terms of 100% by the gross mass of the suspending agent, the suspending agent includes the ingredient of following mass percentage: emamectin benzoate 0.5%~10%；Solubilizer 2%~15%；Wetting agent 1%~3%；Dispersing agent 2%~4%；Antioxidant 0.5%~2%；Anti-drift agent 3%~10%；Antifreezing agent 2%~5%；Thickener 0.1%~3%；Defoaming agent 0.2%~0.4%；Preservative 0.1%~0.5%；Surplus is water.The suspending agent makes emamectin benzoate play consistently drug action by the synergistic effect of each ingredient and content, reduces use cost, and because being free of organic solvent, safety when producing and using is environmentally friendly.
Description
Technical field
The invention belongs to technical field of pesticide, and in particular to a kind of suspending agent and preparation method thereof.
Background technique
In recent years, agricultural plant protection unmanned plane flies the fast development of anti-cause, has nearly ten million mu farmland utilization every year and plants
It protects unmanned plane and carries out spraying operation, plant protection drone is used in pest and disease damage specialization Unifying control, pesticide reduction and plant protection is administered
It played an important role in automatic and mechanical process, can effectively save agriculture sheet, promote prevention and control efficiency.Actually fly anti-work
When industry, to meet the needs of pest and disease damage specialization Unifying control, it is often necessary to contain different effective components, different dosage forms, difference
The preparation bucket of amount is mixed to be used, and conventional low latitude unmanned plane spray dilution medicament total amount requires to be no more than one kilogram per acre, belongs to
Low capacity or ultra-low volume spray, dilution dosage component is more, concentration is high, and easily generation precipitating, crystallization, flocculation, blocking sprayer etc. are existing
As.Since effective component partial size is bigger, the problems such as being more easy to produce precipitating, blocking sprayer, and solvent content is higher, is more easy to produce
The problems such as crystallization, flocculation.Therefore, reduce for flying anti-preparation partial size and reducing solvent contained by preparation, it is compatible to preparation is promoted
Property and stability are extremely important.
Emamectin-benzoate (referred to as " emamectin benzoate "), with fermented product avermectin B1As parent chemical combination
Object is reacted by Wilkinson carries out the new and effective semi-synthetic macrolides desinsection antibiosis of one kind that structural modification obtains
Element.The emamectin benzoate active compound content of China's registration production is 79.1%~95%, and raw medicine impurity content is higher, and due to production technology
Complexity causes impurity composition more, and nature difference is big.
Currently, more and more for flying anti-preparation just in exploitation.CN106962371 is described for flying anti-first dimension
Salt dry suspending agent and preparation method thereof, the emamectin benzoate D98Partial size≤5 μm.CN106172385 is described for flying anti-pesticide
Dry suspending agent and preparation method thereof, the dry suspension partial size D comprising emamectin benzoate905 μm of <.CN107646840, which is described, includes
Water-based pesticide low capacity agent of emamectin benzoate and preparation method thereof.CN106417271 describes a kind of sprayed by unmanned plane and shines prevention and treatment
The medicament of rice leaf roll snout moth's larva, the medicament are 5% emamectin benzoate microemulsion.
Above-mentioned patent is all proved emamectin benzoate and is flying to be widely used on anti-, and the emamectin benzoate system of above-mentioned production or exploitation
Agent partial size is mostly micron order.Nanometer formulation is thin to plant and pest since effective component partial size is in nano-scale range
Born of the same parents have excellent permeability, and absorptivity is high, and dilution stability is good, have superior characteristic.Existing emamectin benzoate nanometer formulation is can
Solution and microemulsion, it is main to be dissolved emamectin benzoate and impurity dissolution or other effective components by screening suitable solvent, then sieve
Suitable emulsifying agent emulsion dispersion is selected to be made, but it is difficult to prepare the nanometer that emamectin benzoate is compounded with the effective component of poor solubility
Preparation, and the environmentally safe property of solvent is low, increases production cost.The open method for preparing nano suspension concentrate mainly has two at present
Kind: such as method (1) patent CN1486606B, principle is related to phase transfer, recrystallization and the special physics and chemistry using nano material
The a small amount of solvent of effective component insecticide is first dissolved, is mixed with surfactant, nano inorganic material by matter, is stirred to get
Even oil phase；Effective component can also be melted with surfactant and be mixed with nano inorganic material, stir to get oily phase, it can also
Effective component, surfactant, nano inorganic material are mixed, then water, antifreeze etc. are mixed, form uniform water
Oil is added to water phase under room temperature and high shear agitation or water phase is added to oily phase by phase, and it is outstanding to form well dispersed water
Supernatant liquid；Such as method (2) patent CN104869820B, principle with prepare the similar of Conventional suspending agents, using subparticle poly-
Characteristic in ether alkanolamine comb polymer solutions, first by one or more activating agents with the water solubility less than 100ppm
It is mixed with Polyetheralkanolamindispersants comb polymer and enough water to generate the aqueous liquid dispersion for including at least activating agent of 25wt%；
The average diameter of the particle in the aqueous liquid dispersion is mechanically set to be reduced to less than 300nm.
But in practical applications, in order to and Zhiduo County's kind disease pest, promote preventive effect or delaying drug resistance, it is generally mixed or will using bucket
Plurality of active ingredients is processed into compound preparation use.When researching and developing compound preparation, due to the physicochemical property of different effective component
Difference prepares compounding nano suspension concentrate using the above method and has following defects that first method is not suitable for preparation and contains Gao Rong
The effective component of point or poor solubility can not obtain uniform oil mutually or the cost of the uniform oily phase of acquisition is too high；Second method
Be not suitable for effective component of the preparation containing the water solubility greater than 100ppm, being similar to emamectin benzoate, (water solubility is at 20 DEG C
240ppm (pH=7) or 300ppm (pH=5)) etc. be slightly soluble in water compound be not suitable for using this method.
Solubilization, solubilized effect are also in solubilization, and definition refers to Cucumber, in Action of Surfactant
Under, the phenomenon that solubility in a solvent dramatically increases.Surfactant with solubilization is known as solubilizer, solubilized
The Cucumber of liquid or solid is known as hydrotrope.Micella can be formed when the concentration of solubilizer is higher than critical micelle concentration (CMC),
Micella again can dissolve into the solute not being dissolved also or other auxiliary agents not readily dissolved in micella, obtain transparent micellar solution, grain
Diameter is in 10nm~100nm.
Summary of the invention
It is an object of the invention to overcome the above-mentioned deficiency of the prior art, a kind of suspending agent and preparation method thereof, purport are provided
In the technical problem for solving to be currently used for winged anti-emamectin benzoate formulation efficacy and stability is undesirable and preparation is at high cost.
For achieving the above object, The technical solution adopted by the invention is as follows:
One aspect of the present invention provides a kind of suspending agent, is the suspending agent packet in terms of 100% by the gross mass of the suspending agent
Include the ingredient of following mass percentage:
Emamectin benzoate 0.5%~10%；
Solubilizer 2%~15%；
Wetting agent 1%~3%；
Dispersing agent 2%~4%；
Antioxidant 0.5%~2%；
Anti-drift agent 3%~10%；
Antifreezing agent 2%~5%；
Thickener 0.1%~3%；
Defoaming agent 0.2%~0.4%；
Preservative 0.1%~0.5%；
Surplus is water.
The present invention provides a kind of suspending agent containing emamectin benzoate, and the suspending agent is anti-in use, anti-drift agent can make for flying
Suspending agent prevents from drifting about in the sky, thus it is more accurate using medicine, and emamectin benzoate and solubilizer will form micella in suspending agent, the glue
Beam has good biocompatibility, readily penetrates through epidermis and enters in pest body, while solubilizer increases the profit of suspending agent again
Therefore wet and penetrating power is more advantageous to the drug action for playing its emamectin benzoate, and the suspending agent containing the micella be it is a kind of more
Add stable nano-dispersion system, the storage stability of suspending agent can be improved in this way；Meanwhile the wetting agent in the suspending agent and point
The effect of powder more promotes the dissolution of emamectin benzoate, and antioxidant, antifreezing agent and preservative adapt suspending agent to different rings
Performance is stablized in border.In short, synergistic effect of the suspending agent by each ingredient and content, makes emamectin benzoate play consistently drug effect work
With, use cost is reduced, and because being free of organic solvent, it is safe when producing and using, it is environmentally friendly.
Another aspect of the present invention provides a kind of preparation method of suspending agent, includes the following steps:
Ingredient contained by above-mentioned suspending agent according to the invention and its content weigh each component materials respectively；
By the emamectin benzoate, wetting agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and prevent
Rotten agent is soluble in water, is ground, and obtains mixed liquor；
The solubilizer is dissolved in the mixed liquor, the suspending agent is obtained.
The preparation method production technology and equipment of suspending agent provided by the invention are simple, at low cost, which first will
Emamectin benzoate, wetting agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and preservative is soluble in water grinds
Mill, obtains the mixed liquor of micro-size particles, after solubilizer is then dissolved in the mixed liquor, emamectin benzoate particle in mixed liquor into
One step is dissolved in the micella of solubilizer formation, obtains emamectin benzoate micellar solution, and micellar solution is a kind of more stable nanometer point
Granular media system, to improve the storage stability of suspending agent, while solubilizer can also improve the wetting of suspending agent, osmotic energy
Power, therefore, final suspending agent obtained is for that can make emamectin benzoate play consistently drug action, and because not containing when flying anti-
Safety when solvent, production and use, it is environmentally friendly.
Specific embodiment
In order to which technical problems, technical solutions and advantageous effects to be solved by the present invention are more clearly understood, below in conjunction with
Embodiment, the present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only used to explain
The present invention is not intended to limit the present invention.
On the one hand, the embodiment of the invention provides a kind of suspending agents, are institute in terms of 100% by the gross mass of the suspending agent
State the ingredient that suspending agent includes following mass percentage:
Emamectin benzoate 0.5%~10%；
Solubilizer 2%~15%；
Wetting agent 1%~3%；
Dispersing agent 2%~4%；
Antioxidant 0.5%~2%；
Anti-drift agent 3%~10%；
Antifreezing agent 2%~5%；
Thickener 0.1%~3%；
Defoaming agent 0.2%~0.4%；
Preservative 0.1%~0.5%；
Surplus is water.
The embodiment of the present invention provides a kind of suspending agent containing emamectin benzoate, and the suspending agent is anti-in use, anti-drift for flying
Agent can make suspending agent prevent from drifting about in the sky, thus it is more accurate using medicine, and emamectin benzoate and solubilizer will form glue in suspending agent
Beam, the micella have good biocompatibility, readily penetrate through epidermis and enter in pest body, while solubilizer increases suspension again
Therefore the wetting and penetrating power of agent are more advantageous to the drug action for playing its emamectin benzoate, and the suspending agent containing the micella is
A kind of more stable nano-dispersion system, can be improved the storage stability of suspending agent in this way；Meanwhile the wetting in the suspending agent
Agent and the effect of dispersing agent more promote the dissolution of emamectin benzoate, and antioxidant, antifreezing agent and preservative are adapted to suspending agent not
Performance is stablized in same environment.In short, the suspending agent plays consistently emamectin benzoate by the synergistic effect of each ingredient and content
Drug action reduces use cost, and because being free of organic solvent, safety when producing and using is environmentally friendly.
Further, in the suspending agent of the embodiment of the present invention, the partial size of the emamectin benzoate is 10nm~100nm.This hair
Emamectin benzoate and solubilizer in bright embodiment will form nanoscale micella, and nanoscale preparation can be to plant and pest cell
With better permeability, and absorptivity is high, dilution stability is good, therefore, when emamectin benzoate partial size 10nm~100nm item
Under part, it is more likely formed micella and plays its drug action.Specifically, the content of emamectin benzoate be 0.5%~10%, preferable 2%~
10%, specially 2%, 3%, 5%, 6%, 8%, 10% is equivalent.Because emamectin benzoate raw medicine impurity content is higher, and due to producing work
Skill complexity causes impurity composition more, and therefore, when preparing the suspending agent of the embodiment of the present invention, above-mentioned content refers to emamectin benzoate activity
Component content is such as prepared with emamectin benzoate raw medicine, needs suitably to increase the input amount of raw medicine, and emamectin benzoate indissoluble is miscellaneous in final suspending agent
Matter content is generally 0.01%~4%.
Further, in the suspending agent of the embodiment of the present invention, solubilizer is selected from one or more kinds of surface-actives
Agent, and its HLB value (i.e. hydrophilic lipophilic balance) is 12~18, the HLB value within the scope of this can make the solubilizing effect of solubilizer most
It is good, to more effectively form nanoscale micella with emamectin benzoate.Preferably, the solubilizer is selected from fatty alcohol polyoxyethylene ether
At least one of with sorbitan fatty acid ester polyoxyethylene ether, the HLB value of these preferred solubilizer can reach above-mentioned
Range.Specifically, the content of solubilizer be 2%~15%, preferable 3%~12%, specially 3%, 6%, 8%, 10%,
12% is equivalent.
Further, in the suspending agent of the embodiment of the present invention, the wetting agent is selected from fatty alcohol polyoxyethylene ether and (moistens
Humectant can also be selected from surfactant), Pluronic PE 6800 (i.e. ethylene oxide/propylene oxide block copolymer) and rouge
At least one of fat alcohol polyoxyethylene ether sulfate；Above-mentioned wetting agent can make solid emamectin benzoate be easier to be spontaneously wet out by water, thus
Preferably it is dissolved in water.The dispersing agent is selected from alkylnaphthalene sulfonate, polycarboxylate, lignosulfonates and polyoxyethylene ether
At least one of phosphate；Above-mentioned dispersing agent can uniform dispersion emamectin benzoate, be dissolved in water it preferably.It is described anti-oxidant
Agent is selected from least one of dibutyl hydroxy toluene, butylated hydroxy anisole and tert-butylhydroquinone；Above-mentioned antioxidant can
Suspending agent aging is prevented, to prolong its service life.The antifreezing agent is in ethylene glycol, propylene glycol, glycerine and urea
It is at least one；Above-mentioned antifreezing agent can prevent suspending agent from freezing at low temperature, so that suspending agent be made to could be used that under cold conditions.
The thickener is selected from least one of aluminium-magnesium silicate, xanthan gum and attapulgite；Above-mentioned thickener is helped as a kind of rheology
Agent is adjustable the rheological characteristic of suspending agent, increases the stability of storage.The defoaming agent is selected from organic silicon defoamer and polyethers defoams
At least one of agent, above-mentioned defoaming agent can further suppress suspending agent and generate bubble.The preservative be selected from sodium benzoate and
At least one of isothiazolinone, foregoing preservatives can further extend the shelf-life of suspending agent.Anti-drift agent is selected from HLB value
For 4~18 nonionic surfactant, specially TERMIX 5920, Silwet DRS 60, G801, G901 etc. can be from cities
The high molecular polymer of commodity board is bought on field；Above-mentioned anti-drift agent can be such that suspending agent size droplet diameter when flying anti-use increases,
To prevent from drifting about, it is administered more accurate.
In the suspending agent of the embodiment of the present invention, the content of wetting agent is 1%~3%；The content of dispersing agent be 2%~
4%；The content of antioxidant is 0.5%~2%；The content of antifreezing agent is 2%~5%；The content of thickener be 0.1%~
3%；The content of defoaming agent is 0.2%~0.4%；The content of preservative is 0.1%~0.5%；The content of anti-drift agent is 3%
~10%.
Further, in the suspending agent of the embodiment of the present invention, the suspending agent further includes the second active constituent, and described
The mass percentage of two active constituents is 1%~30%, and second active constituent is selected from indoxacarb, lufenuron, azoles worm
Amide, metaflumizone, Rynaxypyr, bromine cyanogen insect amide, diafenthiuron, d ichlorbenzuron, flubenzuron, tebufenozide and methoxyfenozide
At least one of.In the embodiment of the present invention, emamectin benzoate and above-mentioned second active constituent are formed into compound preparation, thus more can be simultaneous
The effect that Zhiduo County plants disease pest, promotes preventive effect or delaying drug resistance.Preferably, the partial size of second active constituent is 1 μm~5 μm.
On the other hand, the embodiment of the invention also provides a kind of preparation method of suspending agent, include the following steps:
S01: ingredient contained by the above-mentioned suspending agent according to the embodiment of the present invention and its content weigh each component materials respectively；
S02: by the emamectin benzoate, wetting agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent
It is soluble in water with preservative, it is ground, obtains mixed liquor；
S03: the solubilizer is dissolved in the mixed liquor, obtains the suspending agent.
The preparation method production technology and equipment of suspending agent provided in an embodiment of the present invention are simple, at low cost, the preparation side
Emamectin benzoate, wetting agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and preservative are first dissolved in by method
It is ground in water, obtains the mixed liquor of micro-size particles, the emamectin benzoate after solubilizer is then dissolved in the mixed liquor, in mixed liquor
Particle is further dissolved in the micella of solubilizer formation, obtains emamectin benzoate micellar solution, micellar solution is a kind of more stable
Nanometer disperse system, to improve the storage stability of suspending agent, while solubilizer can also improve the wetting of suspending agent, seep
Saturating ability, therefore, final suspending agent obtained is for that can make emamectin benzoate play consistently drug action, and because not when flying anti-
Containing organic solvent, safety when producing and using is environmentally friendly.
Further, in above-mentioned steps S02, the milled processed carries out in sand mill, by the way that effect is sanded more,
Obtain micron-sized partial size；Further, further include filtration treatment after the milled processed, can be contained after filtering
Partial size is the mixed liquor of 1 μm~5 μm emamectin benzoate particles.Finally the emamectin benzoate in the particle size range is dissolved in solubilizer, and formation is received
The micella of meter level.
Further, the preparation of built reactive ingredient in order to obtain, by the second active constituent and the emamectin benzoate, wetting
Agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and preservative are soluble in water, carry out at grinding
Reason；Wherein, second active constituent is selected from indoxacarb, lufenuron, Tolfenpyrad, metaflumizone, Rynaxypyr, bromine cyanogen
At least one of insect amide, diafenthiuron, d ichlorbenzuron, flubenzuron, tebufenozide and methoxyfenozide.Then after solubilizer being added,
Surface by wetting agent and dispersant adsorption the second active ingredients particles and emamectin benzoate indissoluble foreign particle stable dispersion in water,
And emamectin benzoate particle is dissolved in the micella of solubilizer formation, obtains emamectin benzoate micellar solution.
In short, there is preferable storage using the suspending agent containing nanometer emamectin benzoate prepared by the preparation method of inventive embodiments
Stability is deposited, the lasting period is long, can effectively reduce spraying times, reduces dosage, environmentally friendly.
Finally, a kind of application method of suspending agent containing nanometer emamectin benzoate for flying to prevent is provided, by the nanometer
Suspending agent is used for low capacity or ultra-low volume spray after dose adds water or spray adjuvants 0.5L~1L to dilute per acre by spray area.
The present invention successively carried out test of many times, and it is further detailed as reference pair invention progress now to lift A partial experiment result
Thin description, is described in detail combined with specific embodiments below.
Embodiment 1
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 1:
Table 1
S11, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S12, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
2% nanometer of emamectin benzoate suspending agent.
Embodiment 2
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 2:
Table 2
S21, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (attapulgite), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S22, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
3% nanometer of emamectin benzoate suspending agent.
Embodiment 3
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 3:
Table 3
S31, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S32, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
5% nanometer of emamectin benzoate suspending agent.
Embodiment 4
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 4:
Table 4
S41, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S42, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
6% nanometer of emamectin benzoate suspending agent.
Embodiment 5
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 5:
Table 5
| Component | Composition/g | Remarks |
| 88% emamectin benzoate raw medicine | 7.7 | Active constituent and indissoluble impurity |
| Fatty alcohol polyoxyethylene ether | 12 | Solubilizer |
| Pluronic PE 6800 | 1.0 | Wetting agent |
| Polyoxyethylene ether phosphate | 3.0 | Dispersing agent |
| Polymeric carboxylic salt | 0.5 | Dispersing agent |
| Tert-butylhydroquinone | 1.5 | Antioxidant |
| G801 | 7.0 | Anti-drift agent |
| Glycerine | 4.0 | Antifreeze |
| 2% xanthan gum mother liquor | 7 | Thickener |
| Attapulgite | 0.6 | Thickener |
| Polyether antifoam agent | 0.4 | Defoaming agent |
| Isothiazolinone | 0.2 | Preservative |
| Water | Supply 100 | Carrier |
S51, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (attapulgite), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S52, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
8% nanometer of emamectin benzoate suspending agent.
Embodiment 6
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 6:
Table 6
| Component | Composition/g | Remarks |
| 90% emamectin benzoate raw medicine | 11.2 | Active constituent and indissoluble impurity |
| Tween-80 | 5 | Solubilizer |
| Fatty alcohol polyoxyethylene ether | 10 | Solubilizer |
| Fatty alcohol polyoxyethylene ether sulfate | 3.0 | Wetting agent |
| Polyoxyethylene ether phosphate | 2.0 | Dispersing agent |
| Polymeric carboxylic salt | 1.0 | Dispersing agent |
| Butylated hydroxy anisole | 2.0 | Antioxidant |
| G901 | 5.0 | Anti-drift agent |
| Ethylene glycol | 4.0 | Antifreeze |
| 2% xanthan gum mother liquor | 5 | Thickener |
| Aluminium-magnesium silicate | 0.5 | Thickener |
| Organosilicon | 0.2 | Defoaming agent |
| Sodium benzoate | 0.3 | Preservative |
| Water | Supply 100 | Carrier |
S61, it weighs active constituent emamectin benzoate raw medicine respectively according to component in above table, is wetting agent, dispersing agent, anti-oxidant
Agent, anti-drift agent, antifreeze, thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μ
M~5 μm suspending agent；
S62, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
10% nanometer of emamectin benzoate suspending agent.
Embodiment 7
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 7:
Table 7
| Component | Composition/g | Remarks |
| 80% emamectin benzoate raw medicine | 1.4 | Active constituent and indissoluble impurity |
| 90% former medicine of indoxacarb | 10.1 | Active constituent |
| Fatty alcohol polyoxyethylene ether | 5.0 | Solubilizer |
| Pluronic PE 6800 | 1.0 | Wetting agent |
| Alkylnaphthalene sulfonate | 2.0 | Dispersing agent |
| Polymeric carboxylic salt | 1.0 | Dispersing agent |
| Dibutyl hydroxy toluene | 0.5 | Antioxidant |
| Silwet DRS 60 | 8.0 | Anti-drift agent |
| Ethylene glycol | 4.0 | Antifreeze |
| 2% xanthan gum mother liquor | 10 | Thickener |
| Aluminium-magnesium silicate | 1.0 | Thickener |
| Organosilicon | 0.2 | Defoaming agent |
| Sodium benzoate | 0.3 | Preservative |
| Water | Supply 100 | Carrier |
S71, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S72, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred and contain to obtain the final product
There is 10% emamectin benzoate indoxacarb suspending agent of nanometer emamectin benzoate.
Embodiment 8
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 8:
Table 8
| Component | Composition/g | Remarks |
| 80% emamectin benzoate raw medicine | 5.1 | Active constituent and indissoluble impurity |
| 98% lufenuron raw medicine | 10.3 | Active constituent |
| Fatty alcohol polyoxyethylene ether | 8.0 | Solubilizer |
| Pluronic PE 6800 | 1.5 | Wetting agent |
| Polymeric carboxylic salt | 2.0 | Dispersing agent |
| Butylated hydroxy anisole | 1.0 | Antioxidant |
| Silwet DRS 60 | 4.0 | Anti-drift agent |
| Ethylene glycol | 4.0 | Antifreeze |
| 2% xanthan gum mother liquor | 8.0 | Thickener |
| Aluminium-magnesium silicate | 0.8 | Thickener |
| Organosilicon | 0.2 | Defoaming agent |
| Sodium benzoate | 0.3 | Preservative |
| Water | Supply 100 | Carrier |
S81, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S82, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred and contain to obtain the final product
There is 14% emamectin benzoate lufenuron suspension agent of nanometer emamectin benzoate.
Embodiment 9
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 1:
Table 9
S91, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S92, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred and contain to obtain the final product
There is 15% emamectin benzoate Tolfenpyrad suspending agent of nanometer emamectin benzoate.
Embodiment 10
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 10:
Table 10
S101, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (attapulgite), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S102, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
The 22% emamectin benzoate metaflumizone suspending agent containing nanometer emamectin benzoate.
Embodiment 11
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 11:
Table 11
S111, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S112, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
The 30% emamectin benzoate diafenthiuron suspension agent containing nanometer emamectin benzoate.
Embodiment 12
A kind of nanometer emamectin benzoate suspending agent for flying to prevent, constituent are as shown in table 12:
Table 12
S121, weighed according to above table active constituent, wetting agent, dispersing agent, antioxidant, anti-drift agent, antifreeze,
Thickener (aluminium-magnesium silicate), defoaming agent, preservative, water, mix, be sanded, filtering partial size be 1 μm~5 μm suspending agents；
S122, solubilizer, thickener (2% xanthan gum mother liquor) are added in suspending agent obtained as above, are sufficiently stirred to obtain the final product
The 30% emamectin benzoate Rynaxypyr suspending agent containing nanometer emamectin benzoate.
It is made using preparation method provided by 1-12 of the embodiment of the present invention for flying anti-hanging containing nanometer emamectin benzoate
Floating agent appearance is uniform；Good fluidity；Cold and hot storage qualified stability；It is store under the conditions of being stored 14 days, -5 DEG C under the conditions of 54 DEG C respectively
It deposits 7 days, resolution ratio, suspensibility, dispersibility, partial size are qualified after heat storage, and specific data are shown in Table 13.
Table 13
In above-mentioned table 13, because Examples 1 to 6 only has a kind of active constituent: i.e. emamectin benzoate, so resolution ratio be the activity at
The specific value divided, and active constituent there are two types of embodiments 7~12, so resolution ratio use≤indicate, mean the resolution ratio
Upper limit value is the maximum resolution ratio in two kinds of active components, i.e., a kind of resolution ratio of active constituent is the upper limit value, and another
The resolution ratio of active constituent is smaller.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (10)
1. a kind of suspending agent, which is characterized in that by the gross mass of the suspending agent be 100% in terms of, the suspending agent include it is as follows
The ingredient of mass percentage:
Emamectin benzoate 0.5%~10%；
Solubilizer 2%~15%；
Wetting agent 1%~3%；
Dispersing agent 2%~4%；
Antioxidant 0.5%~2%；
Anti-drift agent 3%~10%；
Antifreezing agent 2%~5%；
Thickener 0.1%~3%；
Defoaming agent 0.2%~0.4%；
Preservative 0.1%~0.5%；
Surplus is water.
2. suspending agent as described in claim 1, it is characterised in that: the partial size of the emamectin benzoate is 10nm~100nm.
3. suspending agent as described in claim 1, it is characterised in that: the HLB value of the solubilizer is 12~18；And/or
The solubilizer is selected from least one of fatty alcohol polyoxyethylene ether and sorbitan fatty acid ester polyoxyethylene ether.
4. suspending agent as described in claim 1, which is characterized in that the wetting agent is selected from fatty alcohol polyoxyethylene ether, EO/PO
At least one of block copolymer and fatty alcohol polyoxyethylene ether sulfate；And/or
The dispersing agent in alkylnaphthalene sulfonate, polycarboxylate, lignosulfonates and polyoxyethylene ether phosphate extremely
Few one kind；And/or
The antioxidant in dibutyl hydroxy toluene, butylated hydroxy anisole and tert-butylhydroquinone at least one
Kind；And/or
The antifreezing agent is selected from least one of ethylene glycol, propylene glycol, glycerine and urea；And/or
The anti-drift agent is selected from nonionic surfactant, and the HLB value of the anti-drift agent is 4~18.
5. suspending agent as described in claim 1, which is characterized in that the thickener is selected from aluminium-magnesium silicate, xanthan gum and bumps
At least one of stick soil；And/or
The defoaming agent is selected from least one of organic silicon defoamer and polyether antifoam agent；And/or
The preservative is selected from least one of sodium benzoate and isothiazolinone.
6. suspending agent as described in any one in claim 1-5, which is characterized in that the suspending agent further include second activity at
Point, it is described second activity at mass percentage be 1%~30%, and second active constituent be selected from indoxacarb, Acarus tritici
Urea, Tolfenpyrad, metaflumizone, Rynaxypyr, bromine cyanogen insect amide, diafenthiuron, d ichlorbenzuron, flubenzuron, tebufenozide and first
At least one of oxygen tebufenozide.
7. suspending agent as claimed in claim 6, which is characterized in that the partial size of second active constituent is 1 μm~5 μm.
8. a kind of preparation method of suspending agent, which comprises the steps of:
Each component materials are weighed respectively according to ingredient contained by the described in any item suspending agents of claim 1-5 and its content；
By the emamectin benzoate, wetting agent, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and preservative
It is soluble in water, it is ground, obtains mixed liquor；
The solubilizer is dissolved in the mixed liquor, the suspending agent is obtained.
9. preparation method as claimed in claim 8, which is characterized in that the milled processed carries out in sand mill；And/or
It further include filtration treatment after the step of milled processed.
10. preparation method as claimed in claim 8 or 9, which is characterized in that by the second active constituent and the emamectin benzoate, profit
Humectant, dispersing agent, antioxidant, antifreezing agent, thickener, defoaming agent, anti-drift agent and preservative are soluble in water, carry out at grinding
Reason；Wherein,
Second active constituent is selected from indoxacarb, lufenuron, Tolfenpyrad, metaflumizone, Rynaxypyr, bromine cyanogen worm acyl
At least one of amine, diafenthiuron, d ichlorbenzuron, flubenzuron, tebufenozide and methoxyfenozide.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053085A (en) * | 2019-11-20 | 2020-04-24 | 河北威远生物化工有限公司 | Emamectin benzoate B2a and indoxacarb suspoemulsion and preparation method thereof |
| CN111543428A (en) * | 2020-06-01 | 2020-08-18 | 六夫丁作物保护有限公司 | Suspending agent for flight control and preparation method thereof |
| CN114176072A (en) * | 2021-11-10 | 2022-03-15 | 河北兴柏农业科技有限公司 | Emamectin benzoate B2 suspending agent and preparation method thereof |
| CN114600878A (en) * | 2022-04-11 | 2022-06-10 | 山东汤普乐作物科学有限公司 | Emamectin benzoate and thiacloprid suspending agent and preparation method thereof |
| CN114766494A (en) * | 2022-05-25 | 2022-07-22 | 上海生农生化制品股份有限公司 | Insecticidal composition suitable for flying prevention and preparation method thereof |
| CN115812722A (en) * | 2022-09-07 | 2023-03-21 | 深圳诺普信农化股份有限公司 | Nano pesticide water suspending agent and preparation method and application thereof |
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| CN102754643A (en) * | 2012-08-02 | 2012-10-31 | 北京格林泰姆科技有限公司 | Methylamino abamectin benzoate suspending agent and preparation method thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102754643A (en) * | 2012-08-02 | 2012-10-31 | 北京格林泰姆科技有限公司 | Methylamino abamectin benzoate suspending agent and preparation method thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053085A (en) * | 2019-11-20 | 2020-04-24 | 河北威远生物化工有限公司 | Emamectin benzoate B2a and indoxacarb suspoemulsion and preparation method thereof |
| CN111053085B (en) * | 2019-11-20 | 2021-08-10 | 河北威远生物化工有限公司 | Emamectin benzoate B2a and indoxacarb suspoemulsion and preparation method thereof |
| CN111543428A (en) * | 2020-06-01 | 2020-08-18 | 六夫丁作物保护有限公司 | Suspending agent for flight control and preparation method thereof |
| CN114176072A (en) * | 2021-11-10 | 2022-03-15 | 河北兴柏农业科技有限公司 | Emamectin benzoate B2 suspending agent and preparation method thereof |
| CN114600878A (en) * | 2022-04-11 | 2022-06-10 | 山东汤普乐作物科学有限公司 | Emamectin benzoate and thiacloprid suspending agent and preparation method thereof |
| CN114766494A (en) * | 2022-05-25 | 2022-07-22 | 上海生农生化制品股份有限公司 | Insecticidal composition suitable for flying prevention and preparation method thereof |
| CN115812722A (en) * | 2022-09-07 | 2023-03-21 | 深圳诺普信农化股份有限公司 | Nano pesticide water suspending agent and preparation method and application thereof |
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