CN109431522A - Autism early screening device based on name reaction normal form - Google Patents

Autism early screening device based on name reaction normal form Download PDF

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Publication number
CN109431522A
CN109431522A CN201811220414.XA CN201811220414A CN109431522A CN 109431522 A CN109431522 A CN 109431522A CN 201811220414 A CN201811220414 A CN 201811220414A CN 109431522 A CN109431522 A CN 109431522A
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China
Prior art keywords
face
name
reaction
experimenter
module
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CN201811220414.XA
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Chinese (zh)
Inventor
李明
邹小兵
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Duke Kunshan University
Third Affiliated Hospital Sun Yat Sen University
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Duke Kunshan University
Third Affiliated Hospital Sun Yat Sen University
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Priority to CN201811220414.XA priority Critical patent/CN109431522A/en
Publication of CN109431522A publication Critical patent/CN109431522A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/165Evaluating the state of mind, e.g. depression, anxiety
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/167Personality evaluation

Abstract

The invention discloses a kind of autism early screening devices based on name reaction normal form, it include: acquisition module, for acquiring the voice signal for participating in staff's name, the picture signal of experimenter's behavioral activity, the experimenter of participation includes suffering from ASD individual and normal individual;Speech recognition module carries out the time point of name when name reaction test with positioning for identification;Face datection mark module, for the face and profile from face from extraction face characteristic in the initial data of video camera and use reference point identifying technical mark;Children's human face data is preserved for subsequent analysis by face detection module;Characteristic extracting module extracts response delay time, the duration of the reaction, reaction head pose feature of experimenter from the picture and mark tally evidence of the children's face detected;Whether prediction module is that ASD patient carries out assessment prediction to tester.The present invention more standardizes, and is more advantageous to automatization judgement and analysis, can automatically derive result.

Description

Autism early screening device based on name reaction normal form
Technical field
The present invention relates to speech recognition, field of image processing more particularly to it is a kind of based on name reaction normal form it is lonely Disease early screening device, acquire name person's name when audio and subject observation people by name when reaction image data and be subject to Analysis, with the device of assessment prediction autism-spectrum obstacle.
Background technique
Society is big in the past few years to the concern of autism-spectrum obstacle (autism spectrum disorder, ASD) Width rises, and just has 1 people in the U.S., every 68 people and suffers from autism.Although existing ASD appraisal procedure is highly effective, It is time-consuming and laborious;And most of diagnostic methods mainly to communication obstacle, social handicap, repeat stereotypic behavior this three The assessment of aspect.Name response analysis is one of the method being widely used in screening autism.This method needs one and faces The veteran professional's operation experiments of bed, and substantially judged according to clinical experience.It is more that this not only needs diagnosis and treatment personnel to possess The diagnostic experiences in year, non-quantized, nonstandardized technique judgment mode also limit accuracy of the autism by early screening.
Name response analysis, has studied how ASD individual responds called name.These research unanimously think ASD individual with The child of normal growth compares, and often has different behavioural characteristics when by name.So far, most of researchs all rest on It was found that the regular few people in statistical significance apply it on the early screening of autism.
The shortcomings that based on artificial name reaction normal form in practical applications is that it acts individual reaction time, response The measurement and its difficulty of head angle.How systematic acquisition experimental data, and automated using machine learning method Evaluation, become a challenging problem.
Summary of the invention
In view of the above technical problems, the purpose of the present invention is to provide a kind of autism early stages based on name reaction normal form Screening apparatus, the present invention can standardize the collection process of name response data, predict the risk degree of ASD, screening ASD Individual, auxiliary ASD diagnosis, improves the chance of ASD early prediction.
To achieve the above object, the present invention is realized according to following technical scheme:
A kind of autism early screening device based on name reaction normal form characterized by comprising
Acquisition module, for acquiring the voice signal for participating in staff's name, the image letter of experimenter's behavioral activity Number, the experimenter of participation includes with ASD individual and normal individual;
Speech recognition module carries out the time point of name when name reaction test with positioning for identification;
Face datection mark module, for extracting face characteristic from the initial data of video camera and using reference point identifying The face and profile of face at technical mark;
Face detection module for identifying from image data into face and children's face, and distinguishes, by children's face Data are preserved for subsequent analysis;
Characteristic extracting module extracts the reaction of experimenter from the picture and mark tally evidence of the children's face detected Delay time, duration of the reaction, reaction head pose feature;
Prediction module, the prediction module have using ASD label known in training data and the feature extracted, training Supervised learning classifier, and class test is carried out to the feature extracted in test data, to tester whether be ASD patient into Row assessment prediction.
In above-mentioned technical proposal, the response delay time is used to extract the name answering delay time of experimenter, root It is calculated according to following formula:
Latency=Tf-Tc1,
Wherein TfIndicate that video camera detects the time of face, T for the first timec1Indicate the time that the first sound name starts.
In above-mentioned technical proposal, the duration of the reaction is used to extract the name response duration time of experimenter, root It is calculated according to following formula:
Duration=Nf/ framerate,
Wherein, NfExpression detects the number of image frames of experimenter's face, and framerate each second, how many was for analyzing Frame data.
In above-mentioned technical proposal, the reaction head pose feature is by n face key feature points (land marker) Picture coordinate data, is calculated according to the following formula:
F=[x '1-x′2,…,x′1-x′n,x′2-x′3,…,x′n-1-x′n,
y′1-y′2,…,y1-y′n,y2-y′3,…,y′n-1-y′n]
Wherein xi,yiIt is the coordinate of i-th of key point, xi' and yi' normalization formula calculating according to the following formula:
Compared with the prior art, the invention has the following advantages:
The invention proposes the frame based on machine learning, the outer phenotypic characteristic of subordinate act sets out, when to subject by name The different mode of responsing reaction is analyzed, and a kind of early screening device for predicting ASD is put forward.It is manually cried compared to traditional Name normal form diagnostic method, method data proposed by the present invention more standardize, and are more advantageous to judgement and analysis, and can automatically derive As a result.Although device proposed by the present invention can not substitute traditional ASD diagnostic method completely, an ASD can be considered and commented The auxiliary early screening device estimated, so that the ASD assessment prediction of early stage is more accurately and conveniently.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with Other attached drawings are obtained according to these attached drawings.
Fig. 1 is the present invention prediction total frame construction drawing of ASD device;
The process schematic that device uses in Fig. 2 present invention.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.
As shown in Figure 1, a kind of autism early screening device based on name reaction normal form of the invention, comprising:
Acquisition module, for acquiring the voice signal for participating in staff's name, the image letter of experimenter's behavioral activity Number, the experimenter of participation includes with ASD individual and normal individual;
In the present embodiment, 43 people are tested, wherein 22 people are ASD children, 21 people are normal child.
Speech recognition module carries out the time point of name when name reaction test with positioning for identification;
Specifically, experimental field voice signal is acquired, the time point of staff's first time name is obtained.
Face datection mark module, for extracting face characteristic from the initial data of video camera and using reference point identifying The face and profile of face at technical mark;
Face detection module for identifying from image data into face and children's face, and distinguishes, by children's face Data are preserved for subsequent analysis;The human face data of non-subject children is ignored;
Characteristic extracting module extracts the reaction of experimenter from the picture and mark tally evidence of the children's face detected Delay time, duration of the reaction, reaction head pose feature.
In the present embodiment, identify that the reaction head pose feature of experimenter and number of image frames carry out identification experimenter and be The no time point for making responsing reaction and response and time span.
In above-mentioned technical proposal, the response delay time is used to extract the name answering delay time of experimenter, root It is calculated according to following formula:
Latency=Tf-Tc1,
Wherein TfIndicate that video camera detects the time of face, T for the first timec1Indicate the time that the first sound name starts.
In above-mentioned technical proposal, the duration of the reaction is used to extract the name response duration time of experimenter, root It is calculated according to following formula:
Duration=Nf/ framerate,
Wherein, NfExpression detects the number of image frames of experimenter's face, and framerate each second, how many was for analyzing Frame data.
In above-mentioned technical proposal, the reaction head pose feature by n face key feature points coordinate data, according to Lower formula is calculated:
F=[x '1-x′2,…,x′1-x′n,x′2-x′3,…,x′n-1-x′n,
y′1-y′2,…,y1-y′n,y2-y′3,…,y′n-1-y′n]
Wherein xi,yiIt is the coordinate of i-th of key point, xi' and yi' normalization formula calculating according to the following formula:
In this embodiment, in order to avoid excessively high-dimensional situation, principal component analysis PCA is applied to extract information content most The data of several high dimensions.
The invention also includes prediction module, the prediction module is using ASD label known in training data and extracts Feature, training supervised learning classifier, and carry out class test to the feature extracted in test data is to tester It is no to carry out assessment prediction for ASD patient.
Specifically, by the data characteristics of tester, two classification analysis are carried out using logistic model, assessment will be by result Display instrument is shown as suffering from the value-at-risk of autism.
In this embodiment, the confusion matrix of assessment result such as the following table 1:
Table 1
The accuracy rate of response delay time is 90.7%, and the accuracy rate for weighting response duration time is 90.7%, and name is anti- The accuracy rate for answering the automatic assessment device of normal form is 93%.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore, These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.

Claims (4)

1. a kind of autism early screening device based on name reaction normal form characterized by comprising
Acquisition module, for acquiring the voice signal for participating in staff's name, the picture signal of experimenter's behavioral activity, ginseng With experimenter include with ASD individual and normal individual;
Speech recognition module carries out the time point of name when name reaction test with positioning for identification;
Face datection mark module, for extracting face characteristic from the initial data of video camera and using reference point identifying technology The face and profile of mark face;
Face detection module for identifying from image data into face and children's face, and distinguishes, by children's human face data It is preserved for subsequent analysis;
Characteristic extracting module extracts the response delay of experimenter from the picture and mark tally evidence of the children's face detected Time, duration of the reaction, reaction head pose feature;
Prediction module trains supervised learning classifier using ASD label known in training data and the feature extracted, And class test is carried out to the feature extracted in test data, it whether is that ASD patient carries out assessment prediction to tester.
2. the autism early screening device according to claim 1 based on name reaction normal form, which is characterized in that described The response delay time is used to extract the name answering delay time of experimenter, calculates according to the following formula:
Latency=Tf-Tc1,
Wherein TfIndicate that video camera detects the time of face, T for the first timec1Indicate the time that the first sound name starts.
3. the autism early screening device according to claim 2 based on name reaction normal form, which is characterized in that described Duration of the reaction is used to extract the name response duration time of experimenter, calculates according to the following formula:
Duration=Nf/ framerate,
Wherein, NfExpression detects the number of image frames of experimenter's face, and framerate is that each second, how many was used for analysis Frame data.
4. the autism early screening device according to claim 3 based on name reaction normal form, which is characterized in that described Head pose feature is reacted by n face key feature points coordinate data, is calculated according to the following formula:
F=[x '1-x′2,…,x′1-x′n,x′2-x′3,…,x′n-1-x′n,
y′1-y′2,…,y1-y′n,y2-y′3,…,y′n-1-y′n]
Wherein xi,yiIt is the coordinate of i-th of key point, xi' and yi' normalization formula calculating according to the following formula:
CN201811220414.XA 2018-10-19 2018-10-19 Autism early screening device based on name reaction normal form Pending CN109431522A (en)

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Cited By (5)

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CN110353703A (en) * 2019-07-05 2019-10-22 昆山杜克大学 Autism based on language paradigm behavioural analysis of repeating the words of others like a parrot assesses apparatus and system
CN110364260A (en) * 2019-07-05 2019-10-22 昆山杜克大学 Autism earlier evaluations apparatus and system based on indicative language paradigm
CN112163512A (en) * 2020-09-25 2021-01-01 杨铠郗 Autism spectrum disorder face screening method based on machine learning
CN113080964A (en) * 2021-03-12 2021-07-09 广州市启路健康科技有限公司 Self-closing data processing method and device based on intervention robot
CN114446476A (en) * 2022-01-28 2022-05-06 中南大学湘雅二医院 Construction method, prediction method and device of autism treatment effect prediction model

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110353703A (en) * 2019-07-05 2019-10-22 昆山杜克大学 Autism based on language paradigm behavioural analysis of repeating the words of others like a parrot assesses apparatus and system
CN110364260A (en) * 2019-07-05 2019-10-22 昆山杜克大学 Autism earlier evaluations apparatus and system based on indicative language paradigm
CN110353703B (en) * 2019-07-05 2021-11-09 昆山杜克大学 Autism assessment device and system based on parrot tongue learning language model behavior analysis
CN112163512A (en) * 2020-09-25 2021-01-01 杨铠郗 Autism spectrum disorder face screening method based on machine learning
CN113080964A (en) * 2021-03-12 2021-07-09 广州市启路健康科技有限公司 Self-closing data processing method and device based on intervention robot
CN114446476A (en) * 2022-01-28 2022-05-06 中南大学湘雅二医院 Construction method, prediction method and device of autism treatment effect prediction model

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