CN109419816A - 解纤维素拟杆菌在预防和/或治疗心脏疾病方面的应用 - Google Patents
解纤维素拟杆菌在预防和/或治疗心脏疾病方面的应用 Download PDFInfo
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Abstract
Description
分组 | ST位移(mv)(±S) |
模型组 | 0.061±0.012 |
复方丹参片组 | 0.032±0.016* |
菌剂1组 | 0.028±0.009** |
菌剂2组 | 0.027±0.011** |
菌剂3组 | 0.021±0.012** |
实验分组 | 血粘度(mPa·s) |
模型组 | 2.32 |
菌剂1 | 1.29* |
菌剂2 | 1.41* |
菌剂3 | 1.38* |
通脉降脂片组 | 1.45* |
正常组 | 1.01* |
实验分组 | 第0周 | 第3周 | 第5周 | 第7周 | 第9周 |
模型组 | 92.8±4.8 | 125.86±5.0 | 269.4±6.1 | 322.5±7.8 | 434.27±10.9 |
菌剂1 | 91.7±4.9 | 116.8±6.4 | 239.5±6.9 | 287.2±8.2* | 359.2±9.9** |
菌剂2 | 92.9±5.2 | 120.7±6.0 | 240.2±7.1 | 289.1±8.0* | 361.8±9.6** |
菌剂3 | 91.8±6.0 | 118.6±6.8 | 238.8±7.4 | 280.2±8.7* | 351.4±10.3** |
通脉降脂片组 | 92.3±5.8 | 121.4±6.1 | 243.4±7.0 | 290.5±7.6* | 380±9.8* |
正常组 | 93.01±5.6 | 111.68±5.9 | 156.0±6.0<sup>▲</sup> | 227.0±8.2<sup>▲▲</sup> | 282.5±9.6<sup>▲▲▲</sup> |
原料 | 质量百分比(%) |
菌组分 | 1.0% |
乳糖 | 2.0% |
酵母粉 | 2.0% |
蛋白胨 | 1.0% |
纯净水 | 93.5% |
维生素C | 0.5% |
Claims (8)
Applications Claiming Priority (2)
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PCT/CN2017/099522 WO2019041141A1 (zh) | 2017-08-29 | 2017-08-29 | 解纤维素拟杆菌在制备预防和/或治疗脂质代谢相关疾病制剂中的应用 |
CNPCT/CN2017/099522 | 2017-08-29 |
Publications (2)
Publication Number | Publication Date |
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CN109419816A true CN109419816A (zh) | 2019-03-05 |
CN109419816B CN109419816B (zh) | 2022-12-30 |
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Country | Link |
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US (1) | US11273186B2 (zh) |
EP (1) | EP3677273B1 (zh) |
CN (1) | CN109419816B (zh) |
WO (1) | WO2019041141A1 (zh) |
Cited By (1)
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CN117045686A (zh) * | 2023-10-08 | 2023-11-14 | 首都医科大学附属北京友谊医院 | 解纤维素拟杆菌在制备药物中的应用 |
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US11273186B2 (en) * | 2017-08-29 | 2022-03-15 | Bgi Shenzhen | Application of bacteroides cellulosityticus in preparing a preparation for preventing and/or treating lipid metabolism related diseases |
EP3999085A4 (en) * | 2019-07-19 | 2023-04-26 | Finch Therapeutics Holdings LLC | METHODS AND PRODUCTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES |
CN113521109A (zh) * | 2021-06-28 | 2021-10-22 | 广州知易生物科技有限公司 | 解纤维素拟杆菌在预防和/或治疗炎症性肠病中的应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101945589A (zh) * | 2007-12-21 | 2011-01-12 | 荷兰纽迪希亚公司 | 用于改善肠道微生物群的非消化性碳水化合物的用途 |
WO2019041141A1 (zh) * | 2017-08-29 | 2019-03-07 | 深圳华大基因研究院 | 解纤维素拟杆菌在制备预防和/或治疗脂质代谢相关疾病制剂中的应用 |
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Publication number | Priority date | Publication date | Assignee | Title |
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ES2436251B1 (es) * | 2012-05-25 | 2014-10-08 | Consejo Superior De Investigaciones Científicas (Csic) | Bacteroides cect 7771 y su uso en la prevención y tratamiento de sobrepeso, obesidad y alteraciones metabólicas e inmunológicas. |
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WO2019041141A1 (zh) * | 2017-08-29 | 2019-03-07 | 深圳华大基因研究院 | 解纤维素拟杆菌在制备预防和/或治疗脂质代谢相关疾病制剂中的应用 |
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CN117045686A (zh) * | 2023-10-08 | 2023-11-14 | 首都医科大学附属北京友谊医院 | 解纤维素拟杆菌在制备药物中的应用 |
CN117045686B (zh) * | 2023-10-08 | 2024-02-13 | 首都医科大学附属北京友谊医院 | 解纤维素拟杆菌在制备药物中的应用 |
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EP3677273A1 (en) | 2020-07-08 |
US20200230181A1 (en) | 2020-07-23 |
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