CN109401964B

CN109401964B - Incubator for stem cell culture

Info

Publication number: CN109401964B
Application number: CN201811254875.9A
Authority: CN
Inventors: 曹振芳; 陈礼明; 杨桂娟
Original assignee: Jiangsu Jorten Medical Technology Co ltd
Current assignee: Nanjing Huafang Bioengineering Co ltd
Priority date: 2018-10-26
Filing date: 2018-10-26
Publication date: 2021-11-26
Anticipated expiration: 2038-10-26
Also published as: CN109401964A

Abstract

The invention provides an incubator for stem cell culture, which belongs to the technical field of incubators and comprises a box body and a cavity arranged in the box body, wherein a water tank is arranged at the bottom of the box body, a slope is arranged above the side wall of the water tank, so that the opening of the water tank is gradually reduced from top to bottom, a layer of shock-proof pad is arranged at the bottom surface of the water tank, a water tray is arranged in the water tank, a protection plate which is in sliding connection with the bottom surface of the box body is arranged above the water tray, and a plurality of through holes which are uniformly distributed are formed in the protection plate; the utility model discloses a cultivation box, including box, baffle, storage frame, cavity, baffle, be equipped with 2 at least layers of baffles in the box and will the cavity separates for a plurality of cultivation spaces, the box inside wall is equipped with a plurality ofly to stop gear, the both sides of baffle with stop gear swing joint, be equipped with on the baffle and store the frame, it includes 2 at least layers backup pad that stack from top to bottom to store the frame. The invention can prevent foreign matters from falling into the water tray, the water tray is stably arranged and is not easy to splash water, a plurality of layers of culture bottles can be stored, and the culture bottles are convenient to take and place.

Description

Incubator for stem cell culture

Technical Field

The invention belongs to the technical field of incubators, and particularly relates to an incubator for stem cell culture.

Background

Stem cells are a type of pluripotent cells with the ability to self-replicate, and under certain conditions, can differentiate into a variety of functional cells. The incubator is a common instrument used in stem cell culture engineering, and proper and balanced temperature and humidity are required during stem cell culture. The existing culture box for stem cell culture is characterized in that a water tray for containing deionized water is arranged in a water tank at the bottom of a box, but the water tray cannot be clamped into the water tank once when being arranged, and water splashes out in the process of being clamped into the water tank; usually, there is not the shelter in water tray top, has debris even the blake bottle mistake to fall into the water tray easily, influences cell culture's normal clear. In addition, the space of the existing incubator is limited, the existing incubator is divided into 3-4 storage spaces by partition plates, when the number of culture bottles is large, the culture bottles can only be stacked on the partition plates, and the culture bottles above the culture bottles need to be searched and taken down when the incubator is used, so that the time is wasted.

Disclosure of Invention

The invention aims to provide a culture box for stem cell culture, which can prevent foreign matters from falling into a water tray, the water tray is stably placed and is not easy to splash water, a plurality of layers of culture bottles can be stored, and the culture bottles are convenient to take and place.

The invention provides the following technical scheme:

a stem cell culture incubator comprises a box body and a cavity body arranged in the box body, wherein a water tank is arranged at the bottom of the box body, a slope is arranged above the side wall of the water tank, so that the opening of the water tank is gradually reduced from top to bottom, a layer of shock-proof pad is arranged on the bottom surface of the water tank, a water tray is arranged in the water tank, a protection plate which is in sliding connection with the bottom surface of the box body is arranged above the water tray, and a plurality of through holes which are uniformly distributed are formed in the protection plate; the utility model discloses a cultivation box, including box, baffle, storage frame, cavity, baffle, be equipped with 2 at least layers of baffles in the box and will the cavity separates for a plurality of cultivation spaces, the box inside wall is equipped with a plurality ofly to stop gear, the both sides of baffle with stop gear swing joint, be equipped with on the baffle and store the frame, it includes 2 at least layers backup pad that stack from top to bottom to store the frame.

Preferably, the height of the water tray is higher than that of the water tank, and a tray edge with a downward-inclined tail end is arranged at the edge of the water tray.

Preferably, the protection plate edge is equipped with the handle, the lower surface rigid coupling of protection plate has the pillar, the pillar bottom is equipped with perpendicular pulley, the bottom half is equipped with and holds perpendicular pulley groove of the gliding of perpendicular pulley.

Preferably, the limiting mechanism comprises an upper limiting frame, a lower limiting frame and a limiting channel, the upper limiting frame and the lower limiting frame are symmetrically distributed, the limiting channel is surrounded by the upper limiting frame and the lower limiting frame, the cross section of the limiting channel is in a regular hexagon shape, and limiting blocks matched with the limiting channel are arranged on two sides of the partition board.

Preferably, the limiting block is connected with a transverse pulley, and a transverse pulley groove for accommodating the transverse pulley to slide is formed in the inner side wall of the box body.

Preferably, the bottom of the supporting plate is fixedly connected with a stand column, the upper surface of the supporting plate is provided with a stand column groove clamped with the stand column, and the upper surface of the partition plate is provided with a sliding groove for accommodating the stand column to slide.

Preferably, baffles are arranged on two sides of the supporting plate, the baffles are connected with extension plates, extension grooves for accommodating the extension plates to slide are formed in the supporting plate, stop blocks are arranged at openings of the extension grooves, and side blocks are fixedly connected to one ends, far away from the baffles, of the extension plates.

Preferably, the side edge of the supporting plate is hinged with a label plate positioned below the supporting plate.

Preferably, the lower part of the box body is fixedly connected with a supporting leg, and the bottom of the supporting leg is provided with an anti-skid pad.

The invention has the beneficial effects that:

(1) the slope is arranged above the side wall of the water tank, so that the opening of the water tank is gradually reduced from top to bottom, and when the water tray is placed, the water tray can slide into the bottom of the water tank from the slope and cannot directly fall into the bottom of the water tank, so that water in the water tray is effectively prevented from splashing; the bottom surface of basin is equipped with the one deck antivrbration pad, can reduce the vibrations that the water tray produced when getting into, improves the stationarity that the water tray was laid.

(2) According to the invention, the protective plate which is in sliding connection with the bottom surface of the box body is arranged above the water tray, and the protective plate can shield the water tray by sliding the protective plate, so that foreign matters can be prevented from falling into the water tray, the water tray can be exposed, and the water tray can be conveniently taken out for cleaning or deionized water can be supplemented.

(3) The storage rack is arranged on the partition plate and comprises at least 2 layers of support plates stacked up and down, so that a plurality of layers of culture bottles can be stored, the culture bottles stacked up are not required to be taken down when the culture bottles are taken and placed, the operation is convenient and fast, and the time is saved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged view of a portion of A in FIG. 1;

FIG. 3 is an enlarged view of a portion B of FIG. 1;

FIG. 4 is an enlarged view of a portion of C in FIG. 1;

FIG. 5 is a schematic view of the structure of the storage rack;

FIG. 6 is a schematic view of the structure of the storage shelf when the label plate is pulled out;

FIG. 7 is a schematic top view of the storage rack;

fig. 8 is a schematic top view of the storage shelf with the extension board pulled out.

Labeled as: 1. a box body; 2. a cavity; 3. a limiting mechanism; 31. an upper frame; 32. a lower frame; 33. a limiting channel; 34. a transverse pulley groove; 4. a partition plate; 41. a limiting block; 42. a horizontal pulley; 5. a storage rack; 51. a support plate; 52. a label plate; 53. a baffle plate; 54. a column; 55. an extension plate; 56. an elongated slot; 57. a stopper; 58. an edge block; 59. a column groove; 6. a water tank; 61. a slope; 7. a water pan; 71. coiling; 8. a crash pad; 9. a protection plate; 91. a pillar; 92. a vertical pulley; 93. a handle; 10. a support leg; 11. a non-slip mat; 12. a chute; 13. and a vertical pulley groove.

Detailed Description

As shown in fig. 1 to 8, an incubator for stem cell culture comprises an incubator body 1 and a cavity 2 arranged in the incubator body 1, wherein a supporting leg 10 is fixedly connected to the lower portion of the incubator body 1, and a non-slip pad 11 is arranged at the bottom of the supporting leg 10, so that the incubator can prevent the incubator body 1 from shifting and reduce the influence of the outside on the incubator.

The bottom of the box body 1 is provided with a water tank 6, a slope 61 is arranged above the side wall of the water tank 6, so that the opening of the water tank 6 is gradually reduced from top to bottom, and the bottom surface of the water tank 6 is provided with a layer of shockproof pad 8. A water tray 7 is arranged in the water tank 6, the height of the water tray 7 is higher than that of the water tank 6, a tray edge 71 with the tail end inclined downwards is arranged at the edge of the water tray 7, and the tray edge 71 is used for being held by hands and is convenient for the water tray 7 to take and place. A protection plate 9 which is connected with the bottom surface of the box body 1 in a sliding mode is arranged above the water tray 7, a plurality of through holes which are uniformly distributed are formed in the protection plate 9, and a handle 93 is arranged at the edge of the protection plate 9 and facilitates the protection plate 9 to be pushed and pulled; the lower surface rigid coupling of guard plate 9 has pillar 91, and pillar 91 bottom is equipped with perpendicular pulley 92, and box 1 bottom is equipped with and holds the gliding perpendicular pulley groove 13 of perpendicular pulley 92, and during the push-and-pull guard plate 9, perpendicular pulley 92 removed in perpendicular pulley groove 13, and it is convenient that guard plate 9 pushes and pulls.

At least 2 layers of clapboards 4 are arranged in the box body 1 and divide the cavity 2 into a plurality of culture spaces, a plurality of pairs of limiting mechanisms 3 are arranged on the inner side wall of the box body 1, and two sides of the clapboards 4 are movably connected with the limiting mechanisms 3. The limiting mechanism 3 comprises an upper limiting frame 31, a lower limiting frame 32 and a limiting channel 33 enclosed by the upper limiting frame 31 and the lower limiting frame 32 which are symmetrically distributed, the cross section of the limiting channel 33 is in a regular hexagon shape, limiting blocks 41 matched with the limiting channel 33 are arranged on two sides of the partition plate 4, and the taking and placing of the partition plate 4 can be completed by drawing out or clamping the limiting blocks 41 on two sides of the partition plate 4 into the limiting channel 33. The stopper 41 is connected with horizontal pulley 42, and the box 1 inside wall is equipped with and holds the gliding horizontal pulley groove 34 of horizontal pulley 42, gets when putting the baffle 4, and horizontal pulley 42 removes in horizontal pulley groove 34, can avoid stopper 41 and the contact of box 1 inside wall and produce the friction, is favorable to laying fast and dismantling of baffle 4.

The partition 4 is provided with a storage rack 5, and the storage rack 5 comprises at least 2 layers of support plates 51 which are stacked up and down. The bottom of the support plate 51 is fixedly connected with an upright column 54, the upper surface of the support plate 51 is provided with an upright column groove 59 which is clamped with the upright column 54, the upright column at the bottom of one support plate is clamped into the upright column groove of the other support plate, and the multi-layer support plates can be stacked up and down, so that multi-layer culture bottles can be contained, and the culture bottles can be conveniently taken and placed; the upper surface of the partition board 4 is provided with a sliding groove 12 for accommodating the upright 54 to slide, so that the storage rack 5 can move stably.

The baffle plates 53 are arranged on two sides of the supporting plate 51, the baffle plates 53 are connected with the extension plates 55, the supporting plate 51 is provided with the extension grooves 56 for accommodating the extension plates 55 to slide, when the width of the culture bottle is larger, the extension plates 55 are pulled out of the extension grooves 56, the width of the supporting plate 51 can be enlarged to adapt to the culture bottle, and the baffle plates 53 can prevent the culture bottle from sliding; a stop block 57 is arranged at the opening of the elongated slot 56, a side block 58 is fixedly connected to one end of the elongated slot 55 far away from the baffle plate 53, and when the elongated slot 55 is completely drawn out, the side block 58 is contacted and abutted against the stop block 57, so that the elongated slot 56 is prevented from being completely separated from the elongated slot 55. The side of the supporting plate 51 is hinged with a label plate 52 which is positioned below the supporting plate 51 and is used for marking the storage date and other information of the stem cell culture bottle, the label plate 52 is pulled out when needed, and the label plate 52 can be placed on the lower surface of the supporting plate 51 when not needed.

When the water tray 7 needs to be cleaned, the protection plate 9 is pushed into the box body 1 along the vertical pulley groove 13, the water tray 7 is exposed outside, the tray edge 71 is held by a hand and taken out, after cleaning and deionized water adding, the water tray 7 is placed in the water tank 6, and in the placing process, the water tray 7 slides into the bottom of the water tank 6 along the slope 61 above the water tank 6, so that water in the water tray 7 is effectively prevented from splashing; the bottom surface of the water tank 6 is provided with a layer of shockproof pad 8, so that the shock generated when the water tray 7 enters can be reduced, the placing stability of the water tray 7 is improved, and finally the protection plate 9 is moved back to the position above the water tray 7, so that foreign matters are prevented from falling.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An incubator for stem cell culture is characterized by comprising a box body and a cavity arranged in the box body, wherein a water tank is arranged at the bottom of the box body, a slope is arranged above the side wall of the water tank, so that the opening of the water tank is gradually reduced from top to bottom, a layer of shock-proof pad is arranged on the bottom surface of the water tank, a water tray is arranged in the water tank, a protection plate which is in sliding connection with the bottom surface of the box body is arranged above the water tray, and a plurality of through holes which are uniformly distributed are formed in the protection plate; at least 2 layers of partition plates are arranged in the box body and divide the cavity into a plurality of culture spaces, a plurality of pairs of limiting mechanisms are arranged on the inner side wall of the box body, two sides of each partition plate are movably connected with the limiting mechanisms, a storage rack is arranged on each partition plate, and each storage rack comprises at least 2 layers of support plates which are stacked up and down;

the height of the water tray is higher than that of the water tank, and the edge of the water tray is provided with a tray edge with the tail end inclined downwards;

the edge of the protection plate is provided with a handle, the lower surface of the protection plate is fixedly connected with a support column, the bottom of the support column is provided with a vertical pulley, and the bottom of the box body is provided with a vertical pulley groove for accommodating the vertical pulley to slide;

the limiting mechanism comprises an upper limiting frame, a lower limiting frame and a limiting channel, the upper limiting frame and the lower limiting frame are symmetrically distributed, the limiting channel is surrounded by the upper limiting frame and the lower limiting frame, the cross section of the limiting channel is in a regular hexagon shape, and limiting blocks matched with the limiting channel are arranged on two sides of the partition board;

the limiting block is connected with a transverse pulley, and a transverse pulley groove for accommodating the transverse pulley to slide is formed in the inner side wall of the box body;

the bottom of the supporting plate is fixedly connected with an upright post, the upper surface of the supporting plate is provided with an upright post groove clamped with the upright post, and the upper surface of the partition plate is provided with a sliding groove for accommodating the upright post to slide;

the novel extension plate is characterized in that baffle plates are arranged on two sides of the supporting plate, the baffle plates are connected with extension plates, extension grooves for accommodating the extension plates to slide are formed in the supporting plate, stop blocks are arranged at openings of the extension grooves, and side blocks are fixedly connected to one ends, far away from the baffle plates, of the extension plates.

2. The incubator as claimed in claim 1, wherein the support plate is hinged at its side with a label plate located under the support plate.

3. The incubator according to claim 1, wherein legs are fixed under the case, and the bottom of the legs is provided with a non-slip mat.