CN109364846B - Application of electric stimulation to increase quantum energy commonality of biomolecules - Google Patents
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Abstract
The invention provides application of a technology for increasing quantum energy commonality of biomolecules by electrical stimulation. The method is characterized in that atoms in the biological molecules and electrons outside the atoms have quantum energy level difference, an ultra-weak biological photon imaging system UBIS is used for detection, direct current or alternating current stimulation, electric spark electrical stimulation, electromagnetic stimulation or electric stimulation of the biological molecules by using an electron gun to emit electrons with different intensities and frequencies can be used for improving the quantum energy level of the biological molecules, and the radiation of brain slice biological photons induced by the biological molecules can be obviously increased. Experimental detection proves that the application of the technology for increasing the quantum energy commonality of the biomolecules by electrical stimulation has the characteristics of simple and convenient operation, reliability, high efficiency, good expansibility, rich functions and the like, can be applied to the quantum energy increment of various biomolecules, and has application value in the fields of life medicine research, new medicine development, preparation development, modification of natural and traditional medicines, quantum biomedical prevention and treatment, chemical industry, agricultural production, functional food, environmental protection and the like.
Description
Technical Field
The invention relates to an application of an isotropic technique for quantum energization of biomolecules by using electrical stimulation. Belongs to the technical field of quantum physics, quantum biology and biomedicine. Can also be applied to other wide fields such as new drug development, preparation development, natural and traditional drug modification, quantum biomedical prevention and treatment, chemical industry, agricultural production, functional food and environmental protection, and the like.
Background
The biological system has the function of metabolism, is a typical open system, and has permanent exchange of substances, energy and information with the external environment. From the viewpoint of quantum physics and quantum chemistry, atoms in biomolecules and electrons moving around the atoms are constantly in a quantum motion state, but the important relationship between the quantum motion state and the function of biomolecules is unknown.
Quantum biology is a discipline that utilizes quantum theory to study life sciences. The discipline involves the use of quantum mechanics to study biological processes and molecular dynamic structures. Molecular dynamic structure and energy transfer at the quantum level are studied using quantum biology. However, the application of quantum mechanics and quantum biology to explain biological phenomena is contrary to human intuition.
By using the ultra-weak biophotonic imaging system UBIS, the inventor finds that the excitatory neurotransmitter glutamic acid with the most abundant content in the brain can transfer quantum energy after acting with a receptor thereof, induces the activity and transmission of biophotons on a neural circuit, possibly realizes information communication between neural cells, and has important correlation with the realization of the neural function. It was also found that glutamate, upon acting on its receptor, leads to a decrease in the quantum energy level in its molecule and loses its effect.
Is there a common technical approach to allow biomolecules with reduced quantum energy levels, such as glutamic acid, to regain its molecular quantum energy level and biological activity?
Disclosure of Invention
The invention aims to provide application of a technology for increasing quantum energy common property of biomolecules by electric stimulation, wherein direct current or alternating current stimulation, electric spark electrical stimulation, electromagnetic stimulation or electric stimulation by using electrons emitted by an electron gun with different intensities and frequencies are used for treating biomolecule solution which reduces quantum energy level and partially or completely loses the activity of inducing brain tissue biophoton, and as a result, the biological activity of the biomolecules can be partially or completely recovered, which is related to the increase of the quantum energy level of the biomolecules.
The technical scheme of the invention is as follows:
the electrical stimulation increases the application of the biomolecule quantum energy commonality technique.
The electric stimulation is direct current or alternating current stimulation, electric spark stimulation, electromagnetic stimulation or electric stimulation which is carried out by using an electron gun to emit electrons, wherein the direct current or alternating current stimulation has different intensities and frequencies.
The electric stimulation for increasing the quantum energy of the biological molecules refers to that the electric stimulation is carried out on the biological molecules in different media so as to increase the quantum energy of the biological molecules.
The biological molecules are biological macromolecules or biological micromolecules. The biological macromolecules are nucleic acids, proteins, lipids or polysaccharides; the biological small molecule is amino acid, peptide, neurotransmitter, neuromodulation or hormone.
The biological molecules are various molecules which are biologically or chemically synthesized and can be used for biomedicine, agriculture, food and environmental protection.
The method for increasing the quantum energy of the biological molecules is to utilize an electric stimulation method to implement electron energy transfer or exchange to electrons outside atoms of the biological molecules, so that the level of a specific atomic electron energy level is increased, or the quantum vibration characteristics of the atoms in the molecules are influenced, thereby increasing or changing the activity and the function of the biological molecules.
The electrical stimulation is used for increasing the quantum energy of the biomolecules, and specifically the electrical stimulation is a device consisting of an electrical stimulator, a discharge electrode and a biomolecule solution tank, wherein the electrical stimulator is connected with the discharge electrode, the discharge electrode is arranged in the biomolecule solution tank, the electrical stimulator is used for implementing direct current or alternating current stimulation, electric spark stimulation and electromagnetic stimulation with different intensities and frequencies according to the characteristics of the biomolecules or carrying out electrical stimulation by using an electron gun to emit electrons, the discharge electrode selects electrodes with different properties according to the characteristics of the biomolecules, and the biomolecule solution tank is used for temporarily storing biomolecule solutions in the electrical stimulation process; the method is characterized in that: preparing biomolecule (which can be separated and/or purified) into solution, putting the solution into a biomolecule solution tank with a discharge electrode, selecting the intensity and stimulation mode of an electric stimulator, starting the electric stimulator to stimulate for a certain time (such as 3 hours), and increasing the quantum energy of the biomolecule.
The increase of the quantum energy of the biological molecules is to detect the radiation energy level of the biological molecules directly or indirectly induced biological photons by using an ultra-weak biological photon imaging system UBIS.
The specific case of increasing the quantum energy of the biological molecules by the electric stimulation is as follows: the most abundant excitant neurotransmitter glutamate in the brain causes the reduction of quantum energy and the reduction or disappearance of action after acting on glutamate receptors to induce nerve cell biological photon radiation, while electrical stimulation can recover the glutamate quantum energy and re-induce the biological photon radiation, and the detection of the glutamate-induced brain slice biological photon activity is to evaluate the glutamate energy level by using an ultra-weak biological photon imaging system (UBIS).
The common technology for increasing the quantum energy of the biomolecules by the electric stimulation is called an electric stimulation assisted quantum energy enhancement technology (ESA-QEET). The ESA-QEET employs an electrical stimulator such as a spark machine, a discharge electrode, and a tank of biomolecular solution. The electrical stimulator can implement direct current spark electrical stimulation with different intensities and stimulation modes, and the discharge electrode can select electrodes with different performances according to the characteristics of molecules. The biomolecule solution tank is used for temporarily storing the molecule solution in the electric stimulation process. If separation and purification of the energized biomolecules are desired, this may be accomplished by combining other techniques as the case may be. The detection method of the energy level of the biological molecules is mainly completed by using the ultra-weak biological photon imaging system UBIS developed by people in the technology of the application, and other existing technologies can also be used for detection.
The invention has the following characteristics:
(1) the operation is simple and convenient: the direct current is used for energizing the characteristics of the biomolecules according to the needs, and the quantum energizing effect of the biomolecules can be obtained by selecting proper stimulation intensity and mode, so that the operation is convenient.
(2) There is a reliable assessment technique: the UBIS imaging system can detect the intensity, spectral characteristics and the like of biophoton signals (such as neurobiophoton signals caused by glutamic acid) caused by the action of biomolecules and analyze the effect of biomolecule energization.
(3) The use is extensive: can be widely applied to quantum energization of various biomolecules, has application value in the fields of life medicine science research, new drug development, preparation development, quantum biomedical prevention and treatment, chemical industry, agricultural production, functional food, environmental protection and the like, and is a common technology.
Drawings
FIG. 1 is a graphical representation of the differential effect of electrical stimulation on incapacitating glutamate, with and without the application of the present technology.
FIG. 2 is a graph of a statistical analysis of the differential effect of electrical stimulation on incapacitating glutamate, with and without the application of the present technology.
Fig. 3 is a schematic illustration of a scout photograph of two brain slices imaged with UBIS according to the present invention.
Fig. 4 is a comparison graph of biophotonic imaging at four imaging time points indicated by numerals 1-4 in fig. 1, the upper graph showing the effect after electrical stimulation, and the lower graph showing the effect without electrical stimulation.
Detailed Description
For a better understanding of the present invention, the following examples are included to further illustrate the details, procedures, and practical effects of the present invention. The present invention is not limited to the following embodiments, and those skilled in the art can make various improvements, upgrades, and extensions of the present invention, which are also within the scope of the claims set forth in this application. The invention adopts an ultra-weak biophoton imaging system UBIS, patent No. 201310524951.4, to perform imaging detection and evaluation.
As shown in figure 1, the ESA-QEET technical system adopted by the invention is a device consisting of an electrical stimulator, a discharge electrode and a biomolecule solution tank. The electric stimulator is connected with a discharge electrode, the discharge electrode is arranged in the biomolecule solution tank, and the electric stimulator is used for implementing direct current or alternating current stimulation, electric spark stimulation, electromagnetic stimulation or electric stimulation by using electrons emitted by an electron gun with different intensities and frequencies according to the characteristics of biomolecules; the discharge electrode is made of different materials, the design of the electrode can be selected according to specific biomolecules needing energy increase, and the discharge electrode can be stimulated by adopting various materials, so that the reliability and the effectiveness of stimulation are ensured. The biomolecule solution tank is selected according to specific requirements, and can be an experimental tank with dozens of milliliters or a reaction tank for large industrial production. The material of the reaction tank is designed and selected according to specific application, and the biomolecule solution tank is used for temporarily storing the biomolecule solution in the electrical stimulation process; preparing biological molecules (including separated and purified biological molecules) into a solution, putting the solution into a biological molecule solution tank with a discharge electrode, selecting the strength and stimulation mode of an electric stimulator, starting the electric stimulator to stimulate for a certain time such as 3 hours, and then detecting the condition of quantum energy increase of the biological molecules. The ESA-QEET technical system can be as simple as the research requirement of a laboratory and can also be as complex as an industrial production process.
Related studies suggest that there are different classes of neurotransmitters in the central nervous system that play important roles in brain function, and that their changes are of significant relevance to the pathological mechanisms of neurological and psychiatric diseases. Studies have shown that dysfunction of the neurotransmitter system or projection circuit (e.g., glutamatergic pathways) in the brain may be associated with neuropsychiatric (e.g., schizophrenia and depression) disease pathogenesis. Furthermore, our recent studies have found that glutamate induces the action and transmission of biophotons in the neural circuits, possibly involving photon brain mechanisms. Based on the above, the inventor uses UBIS imaging technology to find that the glutamic acid causes the reduction of the quantum energy level after acting on the receptor and partially or completely loses the function of inducing the activity and transmission of the biological photon, and the inventor finds that the technology can recover the reduced glutamic acid quantum energy level and regain the activity and transmission of the biological photon of the induced nerve circuit.
Example (b): reduction and restoration of glutamate Quantum energy levels
Firstly, detecting materials: adult Kunming mice, from the public service center for laboratory animals in Hubei province.
II, detection step:
(one), reduction and detection of glutamate Quantum level
Preparing artificial cerebrospinal fluid (ACSF) containing (in mM)125NaCl,2.5KCl,2CaCl2,1MgCl2,1.25NaH2PO4,26NaHCO3and 10D-glucose; pH 7.4 glutamic acid was added to 100ml of ACSF in an amount to give a final concentration of 50mM glutamic acid.
Brain tissue from 4 mice was rapidly harvested and sectioned with a vibrating microtome (thickness 450 μ M) starting from the olfactory cortex and ending in the posterior cerebellum. Four mouse whole brain sections were collected and incubated in 100ml total ACSF containing 50mM glutamic acid for 24 hours at room temperature using 95% O2+5％CO2The mixed gas is ventilated to ensure the aerobic metabolism function of brain cells to be normal. All brain slices were removed after 24 hours, i.e. the cerebrospinal fluid after incubation was low-or non-functional glutamic acid ACSF. The detection of the UBIS imaging system finds that the glutamic acid treated in the way partially or completely loses the effect of inducing the biophotonic activity of the brain slices of the mice, but can restore the effect after electric stimulation, and the result is shown in figure 1, figure 2, figure 3 and figure 4. FIG. 1 shows a dynamic process of time-dependent induction of biophoton radiation of mouse brain slices with time by DC spark electrical stimulation (upper line in the figure) and non-stimulation (lower line in the figure) after 24 mice are treated with four mouse whole brain slices containing 50mM glutamic acid ACSF, and the imaging time of each image is 30 seconds. The electrically stimulated glutamate restores the activity of inducing brain slice biophotons, suggesting that quantum energy is restored. Statistical analysis and comparison of 5 replicate cases, shown in figure 2, each point representing the mean relative gray value for 15 minutes. The bottom line represents the effect of incapacitating glutamate action (5 samples), the middle line represents the effect of pluripotent glutamate (5 samples), and the top line represents the effect of normal glutamate (17 samples). Fig. 3 is a scout photograph of two brain slices for UBIS imaging. Fig. 4 is a particular four representative 30 second biophoton imaging grayscale images, corresponding to the imaging time points indicated by numerals 1-4 in fig. 1. The biophoton moving image signal presented in the upper graph of fig. 4 is the effect of glutamic acid that is energized by electric stimulation treatment, while the lower brain slice in fig. 3 presents a very weak biophoton moving image signal at the position of fig. 4, which is the effect of the partially de-energized glutamic acid that is not electrically stimulated.
(II) recovery and detection of glutamic acid quantum energy level
Low or non-functional 50mM glutamic acid containing ACSF100ml was obtained according to the above method. It was then split into two part solutions (50 ml each), with 50ml stimulated with a 12 volt direct current spark for 3 hours. Another 50ml of ACSF was not electrically stimulated as a control. The result shows that the electrically stimulated glutamic acid solution can obviously induce the radiation of brain slice biological photons, and the result is shown in figure 1, figure 2, figure 3 and figure 4, while the partial incapacitated glutamic acid without electric stimulation has very weak effect, and has obvious difference in statistics, which prompts that the electric stimulation restores the quantum energy level of the glutamic acid and induces the action of biological photon activity.
While the invention has been described with reference to specific embodiments, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention as defined in the following claims. Thus, the present discovery is a general technique that requires protection.
Claims (1)
1. The application of the technology for increasing the quantum energy common property of the biomolecules by electrical stimulation adopts a device consisting of an electrical stimulator, a discharge electrode and a biomolecule solution tank, wherein the electrical stimulator is connected with the discharge electrode, the discharge electrode is arranged in the biomolecule solution tank, and the electrical stimulator implements direct current spark electrical stimulation; the discharge electrode selects electrodes with different performances according to the characteristics of biomolecules, and the biomolecule solution tank is used for temporarily storing the biomolecule solution in the electrical stimulation process; the intensity and the stimulation mode of the electric stimulator are selected, and the electric stimulator is started to stimulate for a certain time to ensure that the quantum energy of the biomolecules is increased;
the biomolecule solution is artificial cerebrospinal fluid of low-function or non-function glutamic acid, and the glutamic acid partially or completely loses the function of inducing the biophotonic activity of a brain slice of a mouse;
the added biomolecule quantum energy is electrically stimulated glutamic acid solution and can obviously induce radiation of brain slice biophoton, and the effect of promoting electrical stimulation to recover the quantum energy level of glutamic acid and inducing biophoton activity is promoted;
the method is characterized in that:
(1) preparing artificial cerebrospinal fluid containing 125 mM NaCl,2.5 mM KCl and 2 mM CaCl2,1 mM MgCl2,1.25 mM NaH2PO4,26 mM NaHCO310 mM D-glucose, pH 7.4, glutamic acid was added to 100mL of artificial cerebrospinal fluid in an amount to give a final concentration of 50 mM; taking the brain tissues of 4 mice rapidly after decapitation, slicing the brain tissues by using a vibrating microtome, collecting and putting four whole brain slices of the mice into artificial cerebrospinal fluid containing 50mM glutamic acid and 100ml of total amount for incubation for 24 hours at room temperature from the olfactory cortex to the back of the cerebellum; starting from incubation with 95% O2+5％CO2Ventilating the mixed gas to ensure that the aerobic metabolism function of the brain slice cells is normal; removing all brain slices after 24 hours, namely the incubated cerebrospinal fluid is artificial cerebrospinal fluid with low-functional or non-functional glutamic acid;
(2) 50mL of artificial cerebrospinal fluid containing 50mM of low-or non-functional glutamic acid was stimulated with a 12 volt direct current spark for 3 hours.
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