CN109364829A - A kind of drug production drug intermediate reaction kettle - Google Patents

A kind of drug production drug intermediate reaction kettle Download PDF

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Publication number
CN109364829A
CN109364829A CN201811470131.0A CN201811470131A CN109364829A CN 109364829 A CN109364829 A CN 109364829A CN 201811470131 A CN201811470131 A CN 201811470131A CN 109364829 A CN109364829 A CN 109364829A
Authority
CN
China
Prior art keywords
plate
reaction kettle
drug
shell
intermediate reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811470131.0A
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Chinese (zh)
Inventor
邓照西
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhengzhou Chiral Drug Research Institute Co Ltd
Original Assignee
Zhengzhou Chiral Drug Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhengzhou Chiral Drug Research Institute Co Ltd filed Critical Zhengzhou Chiral Drug Research Institute Co Ltd
Priority to CN201811470131.0A priority Critical patent/CN109364829A/en
Publication of CN109364829A publication Critical patent/CN109364829A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053Details of the reactor
    • B01J19/0066Stirrers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00Feed or outlet devices; Feed or outlet control devices
    • B01J4/008Feed or outlet control devices

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)

Abstract

Design medicine synthesis technical field of the present invention, specifically disclose a kind of drug production drug intermediate reaction kettle, aiming at the problem that existing Manual material feeding not can control inventory, now propose following scheme, it includes tank body, the top of the tank is provided with driving device, driving device output end is provided with shaft, there are three stirring blades for installation in the shaft, the sidewall bottom of the tank body is provided with drainpipe, and its top side wall is provided with connecting tube far from the side of drainpipe, the other end of the connecting tube is connected with chemical tank, the chemical tank includes shell, the outer roof of the shell is provided with push rod, the push rod two sides are respectively arranged with gag lever post and threaded rod, the push rod is fixedly installed with mounting plate after running through shell, the mounting plate bottom is provided with connecting plate, piston plate is provided with below the connecting plate.The present invention has saved resource by controlling inventory, also ensures product quality, reduces the waste of raw material.

Description

A kind of drug production drug intermediate reaction kettle
Technical field
The present invention relates to technical field of medicine synthesis more particularly to a kind of drug production drug intermediate reaction kettles.
Background technique
General pharmaceutical intermediate can use reaction kettle in process of production, presently mainly by manually by scattered raw material It is put into reaction kettle by the feed inlet of reaction kettle upper end, inlet amount cannot be controlled well in this way, substantially reduce finished product Quality, and reaction kettle inner wall is easy to will cause pollution there are residuals after reaction, and it is raw to design a kind of drug for we thus It produces and uses drug intermediate reaction kettle, to solve the above problems.
Summary of the invention
A kind of drug production drug intermediate reaction kettle proposed by the present invention, solves Manual material feeding and not can control and feed intake The problem of amount.
To achieve the goals above, present invention employs following technical solutions:
A kind of drug production drug intermediate reaction kettle, including tank body, the top of the tank are provided with driving device, driving dress It sets output end and is provided with shaft, be fixedly mounted in the shaft there are three stirring blade, the sidewall bottom of the tank body is provided with Drainpipe, and its top side wall is provided with connecting tube far from the side of drainpipe, the other end of the connecting tube is connected with medicament Case, the chemical tank include shell, and the outer roof of the shell is provided with push rod, the push rod two sides be respectively arranged with gag lever post and Threaded rod, and gag lever post and threaded rod run through shell and extend to inside it, the push rod is fixedly installed with peace after running through shell Loading board, the mounting plate bottom are provided with connecting plate, are provided with piston plate below the connecting plate.
Preferably, the gag lever post sliding runs through mounting plate, connecting plate, is finally fixedly mounted on piston plate roof, and position Between connecting plate and piston plate, reset spring is installed on the outer wall of gag lever post, the threaded rod and mounting plate screw thread connect It connects, is slidably connected with connecting plate, and its bottom end is rotatably arranged on piston plate by bearing, the piston plate bottom is equipped with rubber Rubber gasket.
Preferably, it is provided with motor right above the top of the tank center, downward, and its is defeated for the output end of the motor Outlet is connected with speed reducer, and the output end of the speed reducer is fixedly installed with shaft by shaft coupling.
Preferably, there are three round holes to be respectively provided in axisymmetrical structure, every blade for the stirring blade.
Preferably, the chemical tank is provided with water inlet pipe and connecting tube, is mounted on one-way cock inside two nozzles.
Compared with the existing technology, the beneficial effect in the present invention is:
1, the present invention is provided with chemical tank, between the rotation that chemical tank passes through threaded rod can control between connecting plate and piston plate Away from so as to control the space size between piston plate and discharge port, it can the size of a control inventory of chemical tank, The uncertainty for avoiding Manual material feeding, has saved resource, also ensures product quality.
2, by being provided with circular through hole on stirring blade, so that can be stirred is more full and uniform when stirring operation, Be conducive to the abundant reaction between reactant, reduce the waste of raw material.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention;
Fig. 2 is the structural schematic diagram of chemical tank of the invention.
Figure label: 1. tank bodies, 2. motors, 3. speed reducers, 4. mechanical seals, 5. shafts, 6. stirring blades, 7. drainings Pipe, 8. connecting tubes, 9. chemical tanks, 10. shells, 11. push rods, 12. gag lever posts, 13. threaded rods, 14. mounting plates, 15. connecting plates, 16. piston plate.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Embodiment, referring to Fig.1-2, a kind of drug production drug intermediate reaction kettle, including tank body 1 are set at the top of tank body 1 It is equipped with driving device, driving device output end is provided with shaft 5, it is fixedly mounted in shaft 5 there are three stirring blade 6, tank body 1 Sidewall bottom is provided with drainpipe 7, and its top side wall is provided with connecting tube 8 far from the side of drainpipe 7, connecting tube 8 it is another One end is connected with chemical tank 9, and chemical tank includes shell 10, and the outer roof of shell 10 is provided with push rod 11, and 11 two sides of push rod are set respectively It is equipped with gag lever post 12 and threaded rod 13, and gag lever post 12 and threaded rod 13 extend to inside it through shell 10, push rod 11 passes through It is fixedly installed with mounting plate 14 after wearing shell 10,14 bottom of mounting plate is provided with connecting plate 15, and the lower section of connecting plate 15 is provided with Piston plate 16, the sliding of gag lever post 12 run through mounting plate 14, connecting plate 15, are finally fixedly mounted on 16 roof of piston plate, and be located at Between connecting plate 15 and piston plate 16, reset spring, threaded rod 13 and 14 spiral shell of mounting plate are installed on the outer wall of gag lever post 12 Line connection, is slidably connected, and its bottom end is rotatably arranged on piston plate 16 by bearing with connecting plate 15,16 bottom of piston plate peace Equipped with rubber washer, it is provided with motor 2 right above 1 top center of tank body, downward, and its output end connects the output end of motor 2 It is connected to speed reducer 3, the output end of speed reducer 3 is fixedly installed with shaft 5 by shaft coupling, and stirring blade 6 is along axisymmetrical knot Structure is respectively provided on every blade there are three round hole, and chemical tank 9 is provided with water inlet pipe and connecting tube 8, pacifies inside two nozzles Equipped with one-way cock, the present invention is provided with chemical tank 9, chemical tank 9 by the rotation of threaded rod 13 can control connecting plate 15 with Spacing between piston plate 16, so as to control the space size between piston plate 16 and discharge port, it can control medicament The size of 9 inventorys of case, avoids the uncertainty of Manual material feeding, has saved resource, also ensures product quality, stirring By being provided with circular through hole on blade 6, so that can be stirred is more full and uniform, is conducive to reactant when stirring operation Between abundant reaction, reduce the waste of raw material.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ", It is " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " suitable The orientation or positional relationship of the instructions such as hour hands ", " counterclockwise " is to be based on the orientation or positional relationship shown in the drawings, merely to just In description the present invention and simplify description, rather than the equipment of indication or suggestion meaning or element must have a particular orientation, with Specific orientation construction and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for description purposes only, it is not understood to indicate or imply relatively important Property or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Person implicitly includes one or more of the features.In the description of the present invention, the meaning of " plurality " is two or two with On, unless otherwise specifically defined.
Application method: in the use of the present invention, the rotation adjustable connecting plate 15 of threaded rod 13 and piston plate can be passed through Spacing between 16 controls chemical tank 9 and once throws to have adjusted the size in the space between piston plate 16 and discharge port The size of doses, to achieve the purpose that control inventory.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (5)

1. a kind of drug production drug intermediate reaction kettle, including tank body (1), which is characterized in that set at the top of the tank body (1) It is equipped with driving device, driving device output end is provided with shaft (5), and there are three stirring blades for fixed installation on the shaft (5) (6), the sidewall bottom of the tank body (1) is provided with drainpipe (7), and its top side wall is arranged far from the side of drainpipe (7) Have connecting tube (8), the other end of the connecting tube (8) is connected with chemical tank (9), and the chemical tank includes shell (10), described Shell (10) outer roof is provided with push rod (11), and push rod (11) two sides are respectively arranged with gag lever post (12) and threaded rod (13), and gag lever post (12) and threaded rod (13) extend to inside it through shell (10), and the push rod (11) runs through shell (10) it is fixedly installed with after mounting plate (14), mounting plate (14) bottom is provided with connecting plate (15), the connecting plate (15) Lower section be provided with piston plate (16).
2. a kind of drug production drug intermediate reaction kettle according to claim 1, which is characterized in that the gag lever post (12) sliding runs through mounting plate (14), connecting plate (15), is finally fixedly mounted on piston plate (16) roof, and be located at connecting plate (15) between piston plate (16), reset spring, the threaded rod (13) and installation are installed on the outer wall of gag lever post (12) Plate (14) is threadedly coupled, and is slidably connected with connecting plate (15), and its bottom end is rotatably arranged on piston plate (16) by bearing, institute It states piston plate (16) bottom and rubber washer is installed.
3. a kind of drug production drug intermediate reaction kettle according to claim 1, which is characterized in that the tank body (1) it is provided with right above top center motor (2), downward, and its output end is connected with deceleration to the output end of the motor (2) The output end of machine (3), the speed reducer (3) is fixedly installed with shaft (5) by shaft coupling.
4. a kind of drug production drug intermediate reaction kettle according to claim 1, which is characterized in that the paddle There are three round holes to be respectively provided in axisymmetrical structure, every blade for piece (6).
5. a kind of drug production drug intermediate reaction kettle according to claim 1, which is characterized in that the chemical tank (9) it is provided with water inlet pipe and connecting tube (8), is mounted on one-way cock inside two nozzles.
CN201811470131.0A 2018-12-04 2018-12-04 A kind of drug production drug intermediate reaction kettle Pending CN109364829A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811470131.0A CN109364829A (en) 2018-12-04 2018-12-04 A kind of drug production drug intermediate reaction kettle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811470131.0A CN109364829A (en) 2018-12-04 2018-12-04 A kind of drug production drug intermediate reaction kettle

Publications (1)

Publication Number Publication Date
CN109364829A true CN109364829A (en) 2019-02-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811470131.0A Pending CN109364829A (en) 2018-12-04 2018-12-04 A kind of drug production drug intermediate reaction kettle

Country Status (1)

Country Link
CN (1) CN109364829A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112266316A (en) * 2020-10-28 2021-01-26 安徽海顺化工有限公司 Dibromopropane recovery process and recovery equipment thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112266316A (en) * 2020-10-28 2021-01-26 安徽海顺化工有限公司 Dibromopropane recovery process and recovery equipment thereof

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WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20190222

WD01 Invention patent application deemed withdrawn after publication