CN109363792B

CN109363792B - Auxiliary fixator for taking rat brain

Info

Publication number: CN109363792B
Application number: CN201811243071.9A
Authority: CN
Inventors: 李健; 丁轲; 贾艳艳; 李翔; 雷燕
Original assignee: Henan University of Science and Technology
Current assignee: Henan University of Science and Technology
Priority date: 2018-10-24
Filing date: 2018-10-24
Publication date: 2021-06-18
Anticipated expiration: 2038-10-24
Also published as: CN109363792A

Abstract

The invention relates to the field of biological test equipment, in particular to an auxiliary fixator for taking rat brain. The anti-skidding type clamping device comprises two clamping plates which are distributed at intervals, wherein fixing plates are fixedly arranged at the same ends of the two clamping plates in the same direction respectively, a plurality of threaded holes are formed in the two fixing plates respectively, fixing needles are arranged in the threaded holes, external threads used for being matched with the threaded holes are arranged on needle bodies of the fixing needles, and anti-skidding contacts are arranged at one ends of the fixing needles facing the direction between the two fixing plates; the middle position of two splint corresponds respectively and is equipped with the floor, has all seted up the shaft hole on the floor, wears to be equipped with in the shaft hole to be used for the articulated round pin axle of connecting two splint, still overlaps to be equipped with on the round pin axle to be used for promoting two splint rotations so that the torsional spring that two fixed plates are close to each other. The invention can firmly fix the head of the mouse and is convenient to hold by hands or fix on the experiment table, thereby realizing rapid, complete, flexible and safe brain taking.

Description

Auxiliary fixator for taking rat brain

Technical Field

The invention relates to the field of biological test equipment, in particular to an auxiliary fixator for taking rat brain.

Background

In biological experiments for studying brain science, small animals such as rats, mice, hamsters, and guinea pigs are often used as experimental subjects for studying the direction of brain development, brain function, brain morphology, and the like. Taking the brain in the experimental preparation is a key procedure for researching brain science, and the brain taking operation contents comprise dissection, peeling, cutting of head and neck muscles, cutting of a skull, a parietal bone, an occipital bone, a temporal bone, a nasal bone and the like for accommodating the brain, stripping of a dura mater, separation of the brain, the cerebellum, a brainstem, a pituitary gland and the like. The head of the experimental mouse needs to be firmly fixed in the experiment so as to facilitate the operation.

There is no suitable fixing apparatus in the prior art, and the conventional method is as follows: the mouse head is held by the left hand, and the right hand operates scissors and bone scissors to peel skin, remove bone tissues and the like. Because the skin of the head of the mouse has smooth hair, and the head muscle is also smooth even after the skin is peeled and is difficult to fix, the situation that the scissors prick the left hand for fixing the mouse head in the brain taking process occurs occasionally, and the brain tissue is often damaged due to improper matching of the left hand and the right hand, so that the experimental result is influenced, and even the risk of cross infection occurs.

Disclosure of Invention

The invention aims to provide an auxiliary fixator for taking rat brain, which can firmly fix the head of a rat and is convenient to hold by hands or fixed on a laboratory bench, thereby realizing rapid, complete, flexible and safe brain taking.

In order to solve the technical problems, the invention adopts the technical scheme that: an auxiliary fixer for taking rat brain comprises two clamping plates which are distributed at intervals, wherein fixing plates are respectively fixedly arranged at the equidirectional ends of the two clamping plates, a plurality of threaded holes are respectively formed in the two fixing plates, fixing needles are arranged in the threaded holes, external threads used for being matched with the threaded holes are arranged on needle bodies of the fixing needles, and anti-skidding contacts are arranged at the ends of the fixing needles facing the direction between the two fixing plates; the middle position of two splint corresponds respectively and is equipped with the floor, has all seted up the shaft hole on the floor, wears to be equipped with in the shaft hole to be used for the articulated round pin axle of connecting two splint, still overlaps to be equipped with on the round pin axle to be used for promoting two splint rotations so that the torsional spring that two fixed plates are close to each other.

Preferably, one end of each of the two clamping plates, which is far away from the corresponding fixing plate, is provided with a bottom plate, and the bottom plate is provided with a sucker which can be fixed on the test bed through adsorption.

Preferably, a supporting plate for supporting the mouse head is fixedly arranged on one fixing plate and faces to one side of the other fixing plate.

Preferably, four threaded holes are formed in the fixing plate and are distributed in a rectangular shape.

Preferably, two ribs are fixed at intervals on the side of any one splint facing the other splint.

Preferably, the anti-skid contact is made of rubber materials.

Advantageous effects

The fixing needle is arranged on the fixing plate in an adjusting and matching mode, so that one end, provided with the anti-slip head, of the fixing needle is in close contact with musculoskeletal bones on the mouse head, all the fixing needles are clamped and fixed in an all-dimensional mode on the mouse head with the irregular shape, and the problems of low efficiency and high danger caused by the fact that the mouse head is easy to slide in a conventional brain taking mode are solved.

The invention has simple structure, is firm and durable, is easy to clean and maintain, and in the preferred embodiment, the sucking discs are arranged on the two clamping plates, so that the invention which clamps the mouse head can be fixed on the test bed through the sucking discs, the left hand is completely liberated, the brain taking efficiency is further improved, and the risk of hurting people is reduced.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of the cross-sectional structure taken along the line A-A in FIG. 1;

the labels in the figure are: 1. the fixed plate, 2, anti-skidding contact, 3, fixed needle, 4, backup pad, 5, splint, 6, floor, 7, round pin axle, 8, bottom plate, 9, sucking disc, 10, torsional spring.

Detailed Description

As shown in fig. 1 and 2, the auxiliary fixator for taking rat brain comprises two clamping plates 5 which are distributed at intervals, wherein the two clamping plates 5 are strip-shaped straight plates and are made of stainless steel or aluminum alloy materials. In fig. 1, the upper ends of two clamping plates 5 are respectively and fixedly provided with a fixing plate 1, and the fixing plate 1 is also made of stainless steel or aluminum alloy material and is fixedly connected with the corresponding clamping plate 5 in a welding mode. The surfaces of the two fixing plates 1 are distributed oppositely, and a gap between the two fixing plates 1 is used for accommodating a mouse head to be used for taking a brain.

Two floor 6 are equipped with at the interval respectively on the opposite face of two splint 5 intermediate positions, all seted up the shaft hole on floor 6, wear to be equipped with same root round pin axle 7 in the shaft hole to connect two splint 5 are articulated through this round pin axle 7. Thereby can realize that the upper end of two splint 5 (being two fixed plates 1) are close to each other through controlling two splint 5 lower extremes and keeping away from each other to realize preliminary fixed to the mouse head. In the invention, the pin shaft 7 is sleeved with the torsion spring 10 in a compressed state, and two ends of the torsion spring 10 are respectively fixed with the two clamping plates 5, so that the invention can automatically push the two clamping plates 5 to rotate to enable the two fixing plates 1 to approach each other under the action of no external force. The vertical fixation in the right side face bottom that lies in left side fixed plate 1 in figure 1 is equipped with backup pad 4, and the left end welding of backup pad 4 is on left side fixed plate 1, and the right-hand member cooperates with right side fixed plate 1 in order to reserve the space that the sufficient mouse head that is used for holding between two fixed plates 1 with the minimum interval of injecing between two fixed plates 1 to can place the mouse head in backup pad 4 getting the brain in-process.

Four threaded holes are respectively formed in the two fixing plates 1, the four threaded holes in the same fixing plate 1 are distributed in a rectangular shape, and the positions of the threaded holes in the two fixing plates 1 correspond to one another. All be equipped with fixed needle 3 in arbitrary one screw hole, be equipped with on the needle body of fixed needle 3 be used for with the external screw thread of screw hole cooperation installation, fixed needle 3 is equipped with the non-slip contact 2 that adopts the rubber materials preparation towards the one end of direction between two fixed plates 1, accessible rotatory fixed needle 3 moves with control non-slip contact 2 orientation the rat head direction that is located between two splint 5, until closely close the looks with the skin skeleton on the rat head contact for eight fixed needles 3 form all-round three-dimensional centre gripping to the rat head. The head anatomical part of the experimental rat is in an exposed state at the moment, so that an operator can conveniently perform efficient and safe brain debridement operation.

In the process of dissecting and taking the brain, the conventional brain taking operation habit can still be followed, the two clamping plates 5 are held by the left hand, and tools such as scissors and the like are operated by the right hand. In this embodiment, the two clamping plates 5 are respectively provided with a bottom plate 8 at one end away from the corresponding fixing plate 1, the bottom plate 8 is provided with a sucker 9, and after the fixing needle 3 clamps and fixes the mouse head, the mouse head fixing device can be fixed on a test bed through the adsorption effect of the sucker 9, so that the left hand of an operator is completely liberated, and the safety of brain taking operation is further improved. After the brain taking operation is completed, the lower ends of the extrusion clamping plates 5 are close to each other, so that the anti-skid contact 2 is completely separated from the mouse head, namely, the mouse head is conveniently taken down from between the two fixing plates, and the next step of cleaning and maintenance is easy to perform.

Claims

1. An auxiliary fixator for taking rat brain is characterized in that: the anti-skidding type clamping device comprises two clamping plates (5) which are distributed at intervals, wherein fixing plates (1) are fixedly arranged at the same-direction ends of the two clamping plates (5) respectively, a plurality of threaded holes are formed in the two fixing plates (1) respectively, fixing needles (3) are arranged in the threaded holes, external threads used for being installed in a matched mode with the threaded holes are arranged on needle bodies of the fixing needles (3), and anti-skidding contacts (2) are arranged at one ends of the fixing needles (3) facing the direction between the two fixing plates (1); the middle positions of the two clamping plates (5) are respectively and correspondingly provided with a ribbed plate (6), the ribbed plates (6) are respectively provided with a shaft hole, a pin shaft (7) for connecting the two clamping plates (5) in a hinged manner penetrates through the shaft holes, and the pin shaft (7) is also sleeved with a torsional spring (10) for pushing the two clamping plates (5) to rotate so as to enable the two fixing plates (1) to be close to each other;

one ends of the two clamping plates (5) far away from the corresponding fixed plate (1) are respectively provided with a bottom plate (8), and the bottom plates (8) are provided with suckers (9) which can be fixed on a test bed through adsorption;

a supporting plate (4) for supporting the mouse head is fixedly arranged on one fixing plate (1) towards one side of the other fixing plate (1).

2. The auxiliary fixator for taking rat brain according to claim 1, wherein: four threaded holes are arranged on the fixing plate (1) and are distributed in a rectangular shape.

3. The auxiliary fixator for taking rat brain according to claim 1, wherein: two ribbed plates (6) are fixed on the side surface of any one splint (5) facing to the other splint (5) at intervals.

4. The auxiliary fixator for taking rat brain according to claim 1, wherein: the anti-skid contact (2) is made of rubber materials.