CN109362707A - Integrated form embryo cryopreservation device - Google Patents
Integrated form embryo cryopreservation device Download PDFInfo
- Publication number
- CN109362707A CN109362707A CN201811230936.8A CN201811230936A CN109362707A CN 109362707 A CN109362707 A CN 109362707A CN 201811230936 A CN201811230936 A CN 201811230936A CN 109362707 A CN109362707 A CN 109362707A
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- embryo
- embryo cryopreservation
- face
- case
- cover board
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- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 160
- 238000005138 cryopreservation Methods 0.000 title claims abstract description 97
- 238000011068 loading method Methods 0.000 claims abstract description 84
- 238000007710 freezing Methods 0.000 claims abstract description 51
- 230000008014 freezing Effects 0.000 claims abstract description 51
- 238000005192 partition Methods 0.000 claims abstract description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 40
- 239000007788 liquid Substances 0.000 abstract description 21
- 229910052757 nitrogen Inorganic materials 0.000 abstract description 20
- 230000000694 effects Effects 0.000 abstract description 11
- 238000003860 storage Methods 0.000 abstract description 4
- 230000000903 blocking effect Effects 0.000 description 4
- 238000009413 insulation Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000005189 Embolism Diseases 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000010257 thawing Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
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- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Hematology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention discloses integrated form embryo cryopreservation device；Including embryo cryopreservation case, multiple loading plates and cover board；Intrinsic multiple partitions uniform from left to right in embryo cryopreservation case, so as to which multiple freezing chambers will be separated into embryo cryopreservation case；Multiple loading plates are uniformly fixed in cover board rear end face, and correspondence is opposite with multiple freezing chamber locations, and multiple loading plate upper surfaces have embryo's loading chute；Effect: the present invention will be integrated on cover board to the multiple loading plates for loading embryo, cover board is that the support plate shared as multiple loading plates uses and saves handle, so that the scattered laying relative to traditional multiple load bars, occupied space can be reduced, enable subsequent place it on the freezing frame in liquid nitrogen container when greatly improve liquid nitrogen container storage efficiency and make full use of liquid nitrogen container memory space, embryo's loading chute is convenient for the required embryo freezed of loading, so that being not easy to slip away and fall, in turn, using effect of the present invention is good.
Description
Technical field
The present invention relates to medical devices equipment technical fields, in particular, being related to a kind of integrated form embryo cryopreservation device.
Background technique
Existing glass freezing carries bar and is commonly referred to as the freezing blade smooth one is the front end made of high molecular material,
It is to be placed on embryo on blade to carry out freezen protective during use.It thaws when needs after being also convenient for simultaneously
Recovery, still, the carrier arrangement are completed under the monitoring of normal eyesight, and the blade with embryo is carried out quickly with liquid nitrogen
Freezing, and upper plastic tube is covered outside it, it then puts into freezing liquid and is saved again.
Using when above-mentioned carrier arrangement the problem is that: first point, since the temperature of liquid nitrogen is -196 degree, need to put
The blade of embryo is on longer handle, since blade is softer, it is necessary to casing be added in blade exterior, result in blade in this way
And the entire load bar cross section that handle is constituted is larger and longer, so that being occupied when placing it on the freezing frame in liquid nitrogen container empty
Between it is big so that storage efficiency is extremely low and is unable to fully the memory space using liquid nitrogen container, embryo is simply placed on leaf by second point
When on piece, embryo is easy to slip away and fall, so that it is not fine for placing stability.
Whereby, the prior art has much room for improvement.
Summary of the invention
A kind of integrated form embryo cryopreservation device provided it is an object of the invention to overcome the deficiency of the above-mentioned prior art.
The present invention solves technical solution used by prior art problem: a kind of integrated form embryo cryopreservation device, including
Front end face top offer the open embryo cryopreservation case of rectangular-shape structure, multiple loading plates to load embryo and to
Lid closes the cover board of the embryo cryopreservation case front end face open topped；
The embryo cryopreservation case is arranged in left-right direction, and the embryo cryopreservation case internal upper part is uniformly installed with from left to right
Multiple partitions, so that by multiple freezing chambers are separated into from left to right inside the embryo cryopreservation case；Multiple loading plates from
Left-to-right is uniformly fixedly arranged on the cover board rear end face, and correspondence is opposite with multiple freezing chamber locations, and multiple described
The upper surface of loading plate offers embryo's loading chute separately down；
When by the cover plate lid together in the embryo cryopreservation case front end face open topped, multiple loading plates are corresponding to be inserted
As for multiple freezing chambers.
Above technical scheme is further elaborated below:
Preferably, the cover board length and width dimensions and the embryo cryopreservation case front end face length and width dimensions are equal in magnitude.
Preferably, multiple loading plate outer diameters are respectively less than diameter in multiple freezing chamber rooms, and multiple loading plates
It is inserted to when multiple freezing chambers in correspondence, multiple loading plates are corresponding to be located at multiple freezing chamber centers.
Preferably, further include a connecting plate to position the cover board and multiple loading plates；
The embryo cryopreservation case front end face lower part inwardly offers a pull chamber in left-right direction；The connecting plate level
It is fixedly arranged on the cover board rear end face, and capable of sliding back and forth set on the pull chamber.
Preferably, two inner side ends of the pull chamber are installed with a sliding rail respectively along the longitudinal direction, in two sliding rails
It is capable of sliding back and forth respectively to be installed with a draw runner, the corresponding both sides of the face with the connecting plate of the opposite one side of two draw runners
It is fixedly connected.
Preferably, the upper end of the connecting plate offers an overflow launder downwards；Multiple loading plates are respectively positioned on described
The surface of overflow launder.
Preferably, the front end face top of the cover board is evenly provided with multiple to the embryo's instruction that is sticked in left-right direction
The slot tag of label；The position correspondence of multiple slot tags is opposite with the position of multiple loading plates.
Preferably, further include two fastening bolts to lock the cover board Yu the embryo cryopreservation case；
The front end face two sides of the embryo cryopreservation case offer a screw hole respectively backward, and two fastening bolts are along front and back
Cover forward end face two sides are arranged in correspondence, and correspondence is opposite with two screwhole positions；
It is open when the cover plate lid is closed the embryo cryopreservation case front end face, and two fastening bolts are tightened to described in two
When screw hole, the cover board is locked with the embryo cryopreservation case.
Preferably, middle part is installed with a knob under the front end face of the cover board；The both sides of the face of the embryo cryopreservation case point
One is not offered grabs slot suitable for what is lifted.
Preferably, the upper end of the embryo cryopreservation case offers a limiting slot downwards；The bottom of the embryo cryopreservation case
It is convexly equipped with a spacing block set compatible with the limiting slot size with its integrally formed size downwards；
When mutually storing is laminated in the two embryo cryopreservation casees, positioned at the spacing block set of the embryo cryopreservation case bottom surface on upper layer
It is arranged in the limiting slot of the embryo cryopreservation case upper surface of lower layer, so that embryo cryopreservation case described in upper layer and lower layer is mutually fixed.
The beneficial effects of the present invention are:
One, a kind of integrated form embryo cryopreservation device provided by the present invention, in the specific implementation, on the one hand, will be to
The multiple loading plates for loading embryo are integrated on the cover board, and the cover board is the branch shared as multiple loading plates
Fagging uses and saves handle, so that the scattered laying relative to traditional multiple load bars, can greatly reduce occupied space, so that
It is subsequent to greatly improve liquid nitrogen container storage efficiency when placing it on the freezing frame in liquid nitrogen container and make full use of depositing for liquid nitrogen container
Space is stored up, on the other hand, the upper surface of multiple loading plates offers embryo's loading chute separately down, so that convenient for loading
The embryo of required freezing, so that the embryo of required freezing is not easy to slip away and fall, so that the embryo of required freezing places stability
It is good, also, each loading plate all has its independent freezing chamber, so that not vulnerable to the interference of peripheral environment, so that
The subsequent refrigerating effect of the embryo of required freezing is good, and in turn, the present invention is practical, and using effect is good.
Secondly, in the technical scheme, on the one hand, multiple loading plate outer diameters are respectively less than in multiple freezing chamber rooms
Diameter, and multiple loading plates are inserted to when multiple freezing chambers in correspondence, multiple loading plates are corresponding positioned at multiple
The freezing chamber center, also, because of the connection that the invention also includes one to position the cover board and multiple loading plates
Plate；The embryo cryopreservation case front end face lower part inwardly offers a pull chamber in left-right direction；Horizontal fixed of the connecting plate
In the cover board rear end face, and it is capable of sliding back and forth be set to the pull chamber, in this way, when in use, be connected described in pull
Plate may make multiple loading plate correspondences to extend out to outside multiple freezing chamber rooms, so that needed for convenient for loading on it
The embryo of freezing, and when in use, multiple loading plates are only positioned as moving forward and backward, so that will not touch multiple described
Chamber inner wall is freezed, so that its use reliability is good, on the other hand, because the upper end of the connecting plate offers an overflow downwards
Slot；Multiple loading plates are respectively positioned on the surface of the overflow launder, in this way, i.e. so that putting embryo in the loading plate
When, corresponding overflow launder puts the remaining embryo medium of institute in embryonic processes convenient for collecting, so that the remaining embryo medium of institute
It is not easy to splash down to platforms such as desktops, in turn, using effect of the invention can effectively improve.
Thirdly, in the present embodiment, on the one hand, because the front end face top of the cover board is evenly provided in left-right direction
Multiple slot tags to the embryo's indicating label that is sticked；The corresponding position with multiple loading plates in the position of multiple slot tags
Set it is opposite, in this way, for the embryo of different people, with its load the opposite slot tag of Board position be sticked it is opposite with its information
The embryo's indicating label answered can confuse convenient for distinguishing and distinguishing so that will not be hard to tell and mix up when subsequent taking-up defrosting, another
Aspect, because of the fastening bolt that the invention also includes two to lock the cover board Yu the embryo cryopreservation case, in this way, setting
Embryo is put after the loading plate, the cover board and the embryo cryopreservation case are fastened, even if obtaining multiple loading plates not
It can skid off, so that use reliability of the present invention is good, in turn, using effect of the invention can reach best.
Detailed description of the invention
Fig. 1 is the overall structure diagram of integrated form embryo cryopreservation device of the present invention；
Fig. 2 is the usage state diagram of integrated form embryo cryopreservation device of the present invention；
Fig. 3 is the exploded view of integrated form embryo cryopreservation device of the present invention；
Fig. 4 is usage state diagram when two integrated form embryo cryopreservation device item stackings of the present invention are fixed；
Fig. 5 is point of the integrated form embryo cryopreservation device of the present invention when removing the embryo cryopreservation case in another embodiment
Xie Tu；
Fig. 6 is the whole exploded view of the freezing carrier of integrated form embryo cryopreservation device of the present invention in the present embodiment；
The embodiments will be further described with reference to the accompanying drawings for the realization, the function and the advantages of the object of the present invention.
Drawing reference numeral:
Integrated form embryo cryopreservation device 1000；
Embryo cryopreservation case 10；
Partition 101；Freeze chamber 102；Pull chamber 103；Sliding rail 104；Draw runner 105；Screw hole 106；Grab slot 107；Limiting slot
108；Spacing block set 109；
Loading plate 20；
Embryo's loading chute 201；
Cover board 30；
Slot tag 301；Knob 302；
Connecting plate 40；
Overflow launder 401；
Fastening bolt 50；
Insulation blocking sleeve 60；
Freezing carrier 70；
Outer cryovial 701；Interior cryovial 702；Outer embolism 703；Outer quoit 704；The sterile filter column 705 of outer tube；Embryo carries
Bar plug 706；Interior sealing-plug 7061；Embryo's carrier bar 7062；Interior quoit 707；The sterile filter column 708 of inner tube.
Specific embodiment
Below with reference to the drawings and the specific embodiments technical solution that the present invention will be described in detail, to become apparent from, intuitively
Understand invention essence of the invention.
In conjunction with shown in Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5 and Fig. 6；
A kind of integrated form embryo cryopreservation device 1000 provided by the present invention offers open length including front end face top
The embryo cryopreservation case 10 of cube shape structure, multiple loading plates 20 to load embryo and the embryo cryopreservation case 10 is closed to cover
The cover board 30 of front end face open topped；
Wherein, the embryo cryopreservation case 10 is arranged in left-right direction, and 10 internal upper part of embryo cryopreservation case is equal from left to right
Even is installed with multiple partitions 101, so that by multiple freezing chambers are separated into from left to right inside the embryo cryopreservation case 10
102；Multiple loading plates 20 are uniformly fixedly arranged on 30 rear end face of cover board, and corresponding and multiple freezings from left to right
102 position of chamber is opposite, and the upper surface of multiple loading plates 20 offers embryo's loading chute 201 separately down；
When the cover board 30 is covered on the 10 front end face open topped of embryo cryopreservation case, multiple loading plates 20
Correspondence is inserted in multiple freezing chambers 102.
Based on described above, it is clear that, a kind of integrated form embryo cryopreservation device 1000 provided by the present invention, then
It is mainly used as embryo cryopreservation and places carrier use.
On the one hand, the present invention will be integrated on the cover board 30 to the multiple loading plates 20 for loading embryo, described
Cover board 30 is that the support plate shared as multiple loading plates 20 uses and saves handle, so that relative to traditional multiple loads
The scattered laying of bar, can greatly reduce occupied space, enable subsequent place it on the freezing frame in liquid nitrogen container when mention significantly
High liquid nitrogen container storage efficiency and the memory space for making full use of liquid nitrogen container.
On the other hand, because the upper surface of multiple loading plates 20 offers embryo's loading chute 201 separately down, such as
This, then make convenient for loading the required embryo freezed, so that the embryo of required freezing is not easy to slip away and fall, so that required freezing
Embryo place stability it is good.
Also, because each loading plate 20 all has its independent freezing chamber 102, in this way, then make not vulnerable to
The interference of peripheral environment, so that the subsequent refrigerating effect of the embryo of required freezing is good.
In turn, the present invention is practical, and using effect is good.
It is emphasized that in the technical scheme, 30 length and width dimensions of cover board and 10 front end of embryo cryopreservation case
Face length and width dimensions are equal in magnitude.
On this basis, multiple 20 outer diameters of loading plate of the invention are respectively less than multiple 102 internal diameters of freezing chamber,
And multiple loading plates 20 are inserted to when multiple freezing chambers 102 in correspondence, multiple correspondences of loading plate 20 are located at
Multiple 102 centers of freezing chamber.
In addition, the present invention then further includes a connecting plate 40 to position the cover board 30 and multiple loading plates 20；
Wherein, the 10 front end face lower part of embryo cryopreservation case inwardly offers a pull chamber 103 in left-right direction；The company
40 level of fishplate bar is fixedly arranged on 30 rear end face of cover board, and capable of sliding back and forth set on the pull chamber 103.
In this way, which when in use, connecting plate 40 described in pull may make multiple correspondences of the loading plate 20 to extend out to
Outside multiple freezing chambers 102, so that convenient for loading the required embryo freezed on it, and when in use, multiple dresses
Support plate 20 is only positioned as moving forward and backward, so that multiple 102 inner walls of freezing chamber will not be touched, so that it is used reliably
Property is good.
Furthermore in the specific implementation, two inner side ends of the pull chamber 103 of the invention are fixed respectively along the longitudinal direction
There is a sliding rail 104, it is capable of sliding back and forth respectively in two sliding rails 104 to be installed with a draw runner 105, the phase of two draw runners 105
Pair one side correspondence be fixedly connected with the both sides of the face of the connecting plate 40.
In this way, i.e. so that the connecting plate 40 will not slip away, so that between the cover board 30 and the embryo cryopreservation case 10
Always it is connected as one without departing from even if it is good to obtain multiple 20 circumferential direction polarizations of loading plate as a result,.
It should be noted that in the technical scheme, the upper end of the connecting plate 40 offers an overflow launder downwards
401；Multiple loading plates 20 are respectively positioned on the surface of the overflow launder 401.
In this way, i.e. so that corresponding overflow launder 401 puts embryo's mistake convenient for collecting putting embryo when the loading plate 20
The remaining embryo medium of institute in journey, so that the remaining embryo medium of institute is not easy to splash down to platforms such as desktops.
In turn, using effect of the invention can effectively improve.
You need to add is that in the technical scheme, the front end face top of the cover board 30 is uniformly set in left-right direction
It is equipped with multiple slot tags 301 to the embryo's indicating label that is sticked；The positions of multiple slot tags 301 it is corresponding with it is multiple described
The position of loading plate 20 is opposite.
In this way, which the embryo of different people is sticked in the slot tag 301 opposite with its 20 position of loading plate and is believed with it
The corresponding embryo's indicating label of manner of breathing, can be convenient for distinguishing and distinguishing, so that subsequent taking-up will not be hard to tell and mix up when thawing
Confuse.
Need further exist for supplement, in the technical scheme, the invention also includes two to lock the cover board 30 with
The fastening bolt 50 of the embryo cryopreservation case 10；
Wherein, the front end face two sides of the embryo cryopreservation case 10 offer a screw hole 106, the two fastening spiral shells respectively backward
Bolt 50 is corresponding along the longitudinal direction to be arranged in the 30 front end face two sides of cover board, and correspondence is opposite with two 106 positions of screw hole；
It is open when the cover board 30 lid is closed 10 front end face of embryo cryopreservation case, and tighten two fastening bolts 50 to
When two screw holes 106, the cover board 30 is locked with the embryo cryopreservation case 10.
Because of the fastening bolt 50 that the invention also includes two to lock the cover board 30 and the embryo cryopreservation case 10, so
One, embryo is being put after the loading plate 20, the cover board 30 and the embryo cryopreservation case 10 is being fastened, even if much
A loading plate 20 will not skid off, so that use reliability of the present invention is good.
In turn, using effect of the invention can reach best.
Further you need to add is that, in the specific implementation, middle part is installed with a drawing under the front end face of the cover board 30
Hand 302, so that pull and propulsion convenient for the cover board 30；It is suitable that the both sides of the face of the embryo cryopreservation case 10 offer one respectively
Slot 107 is grabbed in what is lifted, so as to set grippers lower part convenient for button, takes and transports to be held in the palm by grippers, such as by it
Crawl is refrigerated into liquid nitrogen container.
And herein it is readily apparent that the present invention in the specific implementation, the length dimension of the embryo cryopreservation case 10 is then
Less than liquid nitrogen container caliber size, so that convenient for its level is placed in liquid nitrogen container.
Also, in the specific implementation, the upper end of the embryo cryopreservation case 10 offers a limiting slot 108 downwards；It is described
The bottom surface of embryo cryopreservation case 10 is downwardly convex to be equipped with one and its integrally formed size and 108 size of limiting slot
Compatible spacing block set 109；
10 bottom surface of embryo cryopreservation case as a result, when putting two 10 phase of the embryo cryopreservation case stackings, positioned at upper layer
Spacing block set 109 be then arranged in the limiting slot 108 of 10 upper surface of embryo cryopreservation case of lower layer, in this way, even if
It obtains embryo cryopreservation case 10 described in upper layer and lower layer to be capable of fixing without relative level displacement, so that being laminated in liquid convenient for multiple present invention
The freezing of embryo is carried out in nitrogen tank.
Furthermore in another embodiment, referring to described in Fig. 5, in the specific implementation, the invention also includes multiple to correspondence
It is arranged the insulation blocking sleeve 60 compatible with its shape of multiple loading plates 20, multiple 60 outer diameters of insulation blocking sleeve are equal
Less than multiple 102 internal diameters of freezing chamber.
In this way, correspondence is arranged after having loaded embryo in embryo's loading chute 201 of multiple loading plates 20 of the invention
Multiple insulation blocking sleeves 60, even if the interior embryo's energy loaded of the embryo's loading chute 201 for obtaining multiple loading plates 20
Obtain further protection be isolated, make it possible to effectively avoid the interference by external environment, even and if make the present invention tilt or
When rollover, spilling will not be fallen, so that embryo cryopreservation good reliability.
And in the specific implementation, as a preferred embodiment, each described the invention also includes being held on referring to shown in Fig. 6
The freezing carrier 70 to device embryo in embryo's loading chute 201 of loading plate 20；
Specifically, in a preferred approach, each freezing carrier 70 includes outer cryovial 701 and is set to described outer
One end of the interior cryovial 702 of 701 inner cavity of cryovial, the outer cryovial 701 is sealed by an outer embolism 703, and the other end is logical
The sealing of outer quoit 704 for offering liquid nitrogen injection hole is crossed, one end that the outer cryovial 701 is sealed with outer quoit 404 is set
There are the sterile filter column 705 of outer tube, the embryo of inner cavity of the one end of the interior cryovial 702 by carrying embryo in interior cryovial 702
It carries bar plug 706 to seal, the other end is sealed by offering the interior quoit 707 of liquid nitrogen injection hole, and the interior cryovial 702 seals
There is one end of interior quoit 707 to be equipped with the sterile filter column 708 of inner tube；It includes for sealing interior cryovial that the embryo, which carries bar plug 706,
It the interior sealing-plug 7061 of 702 one end and is solidified as a whole with the interior sealing-plug 7061 and is frozen the embryo of embryo for carrying and holds
Bar 7062 is carried, embryo's carrier bar 7062 is located at the inner cavity of the interior cryovial 702.
In this way, the present invention passes through sterile 705 He of filter column of the outer tube when injecting liquid nitrogen for the freezing carrier 70 respectively
The sterile filter column 708 of said inner tube is filtered, i.e., is frozen the contaminated risk of embryo so that can effectively eliminate.
In turn, using effect of the invention can obtain optimum optimization.
Other embodiments etc., illustrate one by one here, not doing then.
In conclusion overall structure of the present invention is simple, easily implement, easy to operate, practical, specificity is strong, manufacturing cost
It is low, in structure improvement and technological improvement, do not need to increase too many cost, so that the present invention necessarily has good market
Promotional value, the present invention can be very welcome, can effectively be popularized.
The above description is only a preferred embodiment of the present invention, is not intended to limit scope of patent protection of the invention, all
Using the transformation of equivalent structure made by description of the invention and accompanying drawing content or equivalent process, it is applied directly or indirectly in it
His relevant technical field, is included within the scope of the present invention.
Claims (10)
1. a kind of integrated form embryo cryopreservation device, it is characterised in that: offer open rectangular-shape knot including front end face top
The embryo cryopreservation case of structure, multiple loading plates to load embryo and the embryo cryopreservation case front end face open topped is closed to cover
Cover board；
The embryo cryopreservation case is arranged in left-right direction, and the embryo cryopreservation case internal upper part is uniformly installed with multiple from left to right
Partition, so that by multiple freezing chambers are separated into from left to right inside the embryo cryopreservation case；Multiple loading plates from a left side to
The right side is uniformly fixedly arranged on the cover board rear end face, and correspondence is opposite with multiple freezing chamber locations, and multiple loadings
The upper surface of plate offers embryo's loading chute separately down；
When by the cover plate lid together in the embryo cryopreservation case front end face open topped, multiple loading plates are corresponding be inserted in
Multiple freezing chambers.
2. integrated form embryo cryopreservation device according to claim 1, it is characterised in that: the cover board length and width dimensions with it is described
Embryo cryopreservation case front end face length and width dimensions are equal in magnitude.
3. integrated form embryo cryopreservation device according to claim 2, it is characterised in that: multiple loading plate outer diameters are small
In diameter in multiple freezing chamber rooms, and multiple loading plates are inserted to when multiple freezing chambers in correspondence, Duo Gesuo
It is corresponding positioned at multiple freezing chamber centers to state loading plate.
4. integrated form embryo cryopreservation device according to claim 3, it is characterised in that: further include one to position the lid
The connecting plate of plate and multiple loading plates；
The embryo cryopreservation case front end face lower part inwardly offers a pull chamber in left-right direction；Horizontal fixed of the connecting plate
In the cover board rear end face, and capable of sliding back and forth it is set to the pull chamber.
5. integrated form embryo cryopreservation device according to claim 4, it is characterised in that: two inner side ends of the pull chamber
It is installed with a sliding rail respectively along the longitudinal direction, it is capable of sliding back and forth respectively in two sliding rails to be installed with a draw runner, two cunnings
The opposite one side correspondence of item is fixedly connected with the both sides of the face of the connecting plate.
6. integrated form embryo cryopreservation device according to claim 5, it is characterised in that: the upper end of the connecting plate is downwards
Offer an overflow launder；Multiple loading plates are respectively positioned on the surface of the overflow launder.
7. integrated form embryo cryopreservation device according to claim 5, it is characterised in that: the front end face top edge of the cover board
Left and right directions is evenly provided with multiple slot tags to the embryo's indicating label that is sticked；The position of multiple slot tags is corresponding
It is opposite with the position of multiple loading plates.
8. integrated form embryo cryopreservation device according to claim 5, it is characterised in that: further include two to lock the lid
The fastening bolt of plate and the embryo cryopreservation case；
The front end face two sides of the embryo cryopreservation case offer a screw hole respectively backward, and two fastening bolts are right along the longitudinal direction
Cover forward end face two sides should be arranged in, and correspondence is opposite with two screwhole positions；
It is open when the cover plate lid is closed the embryo cryopreservation case front end face, and two fastening bolts are tightened to two screw holes
When, the cover board is locked with the embryo cryopreservation case.
9. integrated form embryo cryopreservation device according to claim 1-8, it is characterised in that: the front end of the cover board
Middle part is installed with a knob under face；The both sides of the face of the embryo cryopreservation case offer one respectively and grab slot suitable for what is lifted.
10. integrated form embryo cryopreservation device according to claim 1-8, it is characterised in that: the embryo cryopreservation
The upper end of case offers a limiting slot downwards；The bottom surface of the embryo cryopreservation case is downwardly convex, and to be equipped with one integrally formed with it
Size spacing block set compatible with the limiting slot size；
When mutually storing is laminated in the two embryo cryopreservation casees, the spacing block set card positioned at the embryo cryopreservation case bottom surface on upper layer is set
In be located at lower layer embryo cryopreservation case upper surface limiting slot in so that embryo cryopreservation case described in upper layer and lower layer is mutually fixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811230936.8A CN109362707B (en) | 2018-10-22 | 2018-10-22 | Integrated embryo refrigerating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811230936.8A CN109362707B (en) | 2018-10-22 | 2018-10-22 | Integrated embryo refrigerating device |
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| Publication Number | Publication Date |
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| CN109362707A true CN109362707A (en) | 2019-02-22 |
| CN109362707B CN109362707B (en) | 2021-07-13 |
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| CN201811230936.8A Expired - Fee Related CN109362707B (en) | 2018-10-22 | 2018-10-22 | Integrated embryo refrigerating device |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060046243A1 (en) * | 2004-08-27 | 2006-03-02 | Tyho-Galileo Research Laboratories | Method for vitrification of mammalian cells |
| CN106900694A (en) * | 2017-03-15 | 2017-06-30 | 柳州市妇幼保健院 | The efficient egg mother cell of drawer type or embryo cryopreservation carry bar |
| CN107372468A (en) * | 2017-08-31 | 2017-11-24 | 成都众恒智合信息技术有限公司 | A kind of portable medical embryo cryopreservation device |
| CN107372467A (en) * | 2017-08-31 | 2017-11-24 | 成都众恒智合信息技术有限公司 | A kind of medical science human embryo refrigerating plant |
| CN107396919A (en) * | 2017-08-31 | 2017-11-28 | 成都众恒智合信息技术有限公司 | A kind of freezer storage device for being exclusively used in medical science test-tube baby's Embryo storage |
-
2018
- 2018-10-22 CN CN201811230936.8A patent/CN109362707B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060046243A1 (en) * | 2004-08-27 | 2006-03-02 | Tyho-Galileo Research Laboratories | Method for vitrification of mammalian cells |
| CN106900694A (en) * | 2017-03-15 | 2017-06-30 | 柳州市妇幼保健院 | The efficient egg mother cell of drawer type or embryo cryopreservation carry bar |
| CN107372468A (en) * | 2017-08-31 | 2017-11-24 | 成都众恒智合信息技术有限公司 | A kind of portable medical embryo cryopreservation device |
| CN107372467A (en) * | 2017-08-31 | 2017-11-24 | 成都众恒智合信息技术有限公司 | A kind of medical science human embryo refrigerating plant |
| CN107396919A (en) * | 2017-08-31 | 2017-11-28 | 成都众恒智合信息技术有限公司 | A kind of freezer storage device for being exclusively used in medical science test-tube baby's Embryo storage |
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| CN109362707B (en) | 2021-07-13 |
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