CN109350053A - A kind of brain imaging method and its system, equipment, storage medium - Google Patents
A kind of brain imaging method and its system, equipment, storage medium Download PDFInfo
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- CN109350053A CN109350053A CN201811223217.3A CN201811223217A CN109350053A CN 109350053 A CN109350053 A CN 109350053A CN 201811223217 A CN201811223217 A CN 201811223217A CN 109350053 A CN109350053 A CN 109350053A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/0507—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves using microwaves or terahertz waves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
- A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
Abstract
The invention discloses a kind of brain imaging method and its system, equipment, storage mediums, using more bases measurement normal direction brain transmitting microwave signal and receive microwave scattering signal, further according to microwave scattering signal reconstruction brain image, overcome brain image acquisition methods complexity in the prior art and is not easy the technical issues of realizing, the image of quick obtaining brain tissue.
Description
Technical field
The present invention relates to imaging field, especially a kind of brain imaging method and its system, equipment, storage medium.
Background technique
With Chinese Economy Development, the increase of people's job and life stress and diet are irregular, the disease incidence of cerebral apoplexy
More rejuvenation, is increasingly becoming the social disease of a kind of high hair style, high mortality, high disability rate, and severe stroke can cause
Permanent neurologic damage, if acute stage, diagnosing and treating can cause serious complication not in time, or even dead.In medicine
On, it is considered as the gold treatment phase of cerebral apoplexy disease within three hours, normal cerebral tissue is likely to occur after ischemic three hours
Irreversible change, necrosis will occur in ischemic brain cell after six hours.If because of Patients with Cerebral Infarction and Seek early medical advice caused by cerebral apoplexy
Diagnosis, it is possible to which there is no before complete irreversible damage, recovery oxygen supplies and blood supply function, to restore to suffer from the cerebrovascular
The brain cell tissue all or part function of person realizes effective treatment of cerebral apoplexy disease.The early diagnosis of cerebral apoplexy, early treatment can
Be substantially reduced disable, lethality.
It include at present MRI imaging and head CT diagnostic device for the conventional detection means of patients with cerebral apoplexy, volume is huge
Big and irremovable, imaging method is complicated, it is difficult to reach the demand diagnosed in time to patients with cerebral apoplexy, it is understood that there may be delay
Situations such as condition-inference, will miss the gold treatment phase of patients with cerebral apoplexy.
Summary of the invention
The present invention is directed to solve at least some of the technical problems in related technologies.For this purpose, of the invention
One purpose is to provide a kind of brain imaging method and its system, equipment, storage medium, for obtaining the image of brain tissue.
The technical scheme adopted by the invention is that: a kind of brain imaging method, comprising the following steps:
Microwave signal transceiving step using more bases measurement normal direction brain transmitting microwave signal and receives microwave scattering letter
Number；
Image-forming step, according to the microwave scattering signal reconstruction brain image.
Further, the microwave scattering signal includes atmospheric reference reflection signal and brain tissue's reflection signal；
The image-forming step includes:
Time-domain signal obtains sub-step, reflects signal according to the atmospheric reference and signal acquisition is reflected in the brain tissue
Corresponding time-domain signal, the corresponding time-domain signal are respectively environment time-domain signal and brain tissue's time-domain signal；
First calibration signal obtains sub-step, is obtained according to the environment time-domain signal and brain tissue's time-domain signal
First calibration signal, first calibration signal are the difference of brain tissue's time-domain signal and the environment time-domain signal；
Microwave signal two-way time obtains sub-step, obtains microwave signal two-way time using synthetic focusing method；
Intensity value obtains sub-step, obtains image slices according to first calibration signal and the microwave signal two-way time
The intensity value of vegetarian refreshments；
Sub-step is imaged, brain image is reconstructed according to the intensity value of the pixel.
Further, before the intensity value acquisition sub-step further include:
Sub-step is denoised, denoising is carried out to first calibration signal.
It is of the present invention another solution is that a kind of brain imaging system, comprising:
Microwave signal Transmit-Receive Unit, for emitting microwave signal using more bases measurement normal direction brain and receiving microwave scattering
Signal；
Imaging unit, for according to the microwave scattering signal reconstruction brain image.
Further, the microwave scattering signal includes atmospheric reference reflection signal and brain tissue's reflection signal；
The imaging unit includes:
Time-domain signal obtains module, for being obtained according to atmospheric reference reflection signal and brain tissue reflection signal
Corresponding time-domain signal is taken, the corresponding time-domain signal is respectively environment time-domain signal and brain tissue's time-domain signal；
First calibration signal obtains module, for being obtained according to the environment time-domain signal and brain tissue's time-domain signal
The first calibration signal is taken, first calibration signal is the difference of brain tissue's time-domain signal and the environment time-domain signal
Value；
Microwave signal two-way time obtains module, for obtaining microwave signal two-way time using synthetic focusing method；
Intensity value obtains module, for obtaining image according to first calibration signal and the microwave signal two-way time
The intensity value of pixel；
Image-forming module, for reconstructing brain image according to the intensity value of the pixel.
Further, the imaging unit further include:
Module is denoised, for carrying out denoising to first calibration signal.
Further, the microwave signal Transmit-Receive Unit includes signal generating source, data acquisition and transmission module, microwave letter
Number transceiver module, electronic matrix switch module and microwave antenna array, the output end of the signal generating source are adopted with the data
Collection and the connection of the input terminal of transmission module, the data acquisition and transmission module and the microwave signal transceiver module, the electricity
Submatrix switch module is all connected with, and the microwave signal transceiver module is connect with the electronic matrix switch module, the electronics
Matrix switch module is connect with the microwave antenna array, and the imaging unit is acquired with the data and transmission module, described
Electronic matrix switch module is all connected with.
Further, the microwave signal Transmit-Receive Unit further includes the mechanical scanning rotating mould for rotary microwave antenna
Block, the microwave antenna array are connect with the mechanical scanning rotary module, and the imaging unit and the mechanical scanning rotate
Module connection.
It is of the present invention another solution is that a kind of brain imaging equipment, comprising:
At least one processor；And
The memory being connect at least one described processor communication；Wherein,
The memory is stored with the instruction that can be executed by least one described processor, and described instruction is by described at least one
A processor executes, so that at least one described processor is able to carry out the brain imaging method.
It is of the present invention another solution is that a kind of computer readable storage medium, it is described computer-readable to deposit
Storage media is stored with computer executable instructions, the computer executable instructions be used to making computer execute the brain at
Image space method.
The beneficial effects of the present invention are:
A kind of brain imaging method of the present invention and its system, equipment, storage medium are sent out using more bases measurement normal direction brain
It penetrates microwave signal and receives microwave scattering signal, further according to microwave scattering signal reconstruction brain image, overcome prior art midbrain
Portion's image acquiring method is complicated and is not easy the technical issues of realizing, the image of quick obtaining brain tissue.
Detailed description of the invention
Fig. 1 is an a kind of specific embodiment structural block diagram of brain imaging system in the present invention；
Fig. 2 is an a kind of specific embodiment structural schematic diagram of the microwave antenna array of brain imaging system in the present invention；
Fig. 3 is an a kind of specific embodiment structural schematic diagram of more bases measurements in brain imaging system in the present invention；
Fig. 4 is an a kind of specific embodiment flow chart of the image reconstruction algorithm of brain imaging system in the present invention；
Fig. 5 is an a kind of specific embodiment position view of the microwave antenna array of brain imaging system in the present invention；
Fig. 6 is an a kind of specific embodiment pixel position view of brain imaging system in the present invention.
Specific embodiment
It should be noted that in the absence of conflict, the features in the embodiments and the embodiments of the present application can phase
Mutually combination.
Embodiment 1
A kind of brain imaging system, comprising:
Microwave signal Transmit-Receive Unit, for emitting microwave signal using more bases measurement normal direction brain and receiving microwave scattering
Signal；
Imaging unit, for according to the microwave scattering signal reconstruction brain image.
Microwave signal Transmit-Receive Unit is using more bases measurement normal direction brain transmitting microwave signal and receives microwave scattering signal,
Imaging unit further according to microwave scattering signal reconstruction brain image, overcome in the prior art brain image acquisition methods it is complicated and not
The technical issues of easily realizing, the image of quick obtaining brain tissue；For patients with cerebral apoplexy, the image of its brain tissue is obtained
Afterwards, doctor can be assisted to carry out diagnoses and treatment to patients with cerebral apoplexy, reduce the disabling of patients with cerebral apoplexy, lethality.And using micro-
The integrated design of wave signal transmitting and receiving unit will greatly reduce the volume of brain imaging system, have portable and removable
The advantages such as dynamic property, the brain image for overcoming patients with cerebral apoplexy in the prior art obtain that equipment volume is huge and immovable skill
Art problem.
It specifically, is an a kind of specific embodiment structural block diagram of brain imaging system in the present invention with reference to Fig. 1, Fig. 1；At
Realized as unit can be used host computer, and microwave signal Transmit-Receive Unit include signal generating source, data acquisition and transmission module,
Microwave signal transceiver module, electronic matrix switch module, microwave antenna array and the mechanical scanning for rotary microwave antenna
The output end of rotary module, signal generating source is acquired with data and the input terminal of transmission module is connect, data acquisition and transmission mould
Block is all connected with microwave signal transceiver module, electronic matrix switch module, microwave signal transceiver module and electronic matrix switching molding
Block connection, electronic matrix switch module, mechanical scanning rotary module are connect with microwave antenna array, and host computer and data acquire
And transmission module, electronic matrix switch module, mechanical scanning rotary module are all connected with.
Further, with reference to Fig. 1, in the present invention, signal generating source is vector network analyzer, for generating excitation letter
Number.And microwave antenna array is the core of brain imaging system, it can be to cerebral ischemia or brain using microwave antenna array
The brain tissue of bleeding carries out microwave imagery reconstruction.Specifically, microwave antenna array of the invention is classified as broad-band antenna array.Microwave is visited
The bandwidth that signal generally has 5GHZ is surveyed, to reduce serious caused by high-frequency microwave signal is propagated in brain tissue decline
Subtract, microwave frequency selected by system between 1-3GHZ, compare with common simple signal by the ultra-broadband signal of 1-3GHz, can
Enhance image analytic degree, inhibit noise, reduces misdiagnosis rate.Meanwhile the excessive Antenna Design of volume influences the layout of aerial array,
Therefore, microwave antenna array is classified as minimized wide-band aerial array.Further, as shown in Fig. 2, Fig. 2 is a kind of in the present invention
One specific embodiment structural schematic diagram of the microwave antenna array of brain imaging system；Microwave antenna array is classified as hemispherical microwave day
Linear array, multiple microwave antennas for transmitting and receiving are distributed evenly in domed region, closely to wrap up
Brain measures resulting scattered field by microwave antenna array, the dielectric property of tested brain tissue can be restored, to reach
The purpose of Non-invasive detection.Hemispherical microwave antenna array includes multiple emission arrays and receiving array, so that the wave beam of concentration is sent out
It is mapped in brain tissue, to improve the resolution ratio of imaging.I.e. each microwave antenna can independent conduct on microwave antenna array
Transmitting terminal or receiving end are the specific implementations that more bases measure in a kind of brain imaging system in the present invention with reference to Fig. 3, Fig. 3
Example structural schematic diagram；Wherein, circle indicates microwave antenna, and dotted line is microwave signal；When certain microwave days of microwave antenna array
When line is as emission port, these microwave antennas can successively emit wide-band microwave signal in an orderly manner, meanwhile, on microwave antenna array
Remaining antenna is receiving end measurement scattered field, is reconstructed by signal power measured by each receiving end, antenna parameter
Dielectric property, this measurement method are referred to as more base mensurations, by utilizing the signal received via different propagation paths
To obtain the richer information about cerebral tissue change.(transmitting and receiving antenna side are indicated by using multiple poliarizing antennas
To identical array), the signal collection of multi-angle can be further enhanced.
With reference to Fig. 1, the major function of electronic matrix switch module is to select microwave antenna by way of electron scanning
Required transmitting antenna and receiving antenna in array.In order to promote the resolution ratio of imaging, constituted using multiple groups microwave antenna
Microwave antenna array operating mode, microwave antenna array are connected by electronic matrix switch module and microwave signal transceiver module
It connects, host computer can realize the compound of microwave signal transceiver module by the working sequence of modification electronic matrix switch module
It uses, can greatly reduce the hardware cost of brain imaging system；Specifically, host computer is incoming electric by the logical sequence of setting
Submatrix switch module carries out signal transmission and controls it simultaneously to control low and high level switching to control some microwave antenna
He carries out signal reception by microwave antenna；Simultaneously as the opening and closing function of electronic matrix switch module, is by external height
Logic level control more improves the flexibility of the operating mode switching of microwave antenna array.Therefore, it is switched in electronic matrix
Under the auxiliary of module, the work of each group microwave antenna in microwave antenna array is realized using same microwave signal transceiver module,
It is opposite to use for multiple groups microwave signal transceiver module, the hardware cost of brain imaging system can not only be reduced, while also can
Enough consistency and stabilization for keeping microwave signal transceiver module to the full extent, can keep the fidelity of signal to a certain extent
Degree, reduces the influence of external hardware factor.
With reference to Fig. 1, mechanical scanning rotary module is used to control the rotation of microwave antenna in microwave antenna array, including rotation
Stepping, selection speed etc., host computer can easily change microwave antenna by the stepping of setting mechanical scanning rotary module very much
The physical location of array, being both avoided that aerial array arrangement excessively intensively there are problems that coupling each other, be moved using micro-stepping
It is dynamic also to collect more accurate microwave data signal, promote the precision of microwave three-dimensional reconstruction algorithm.And data acquisition and biography
Defeated module, which is mainly responsible for, chooses proper signal as excitation antenna signal, and acquires the microwave signal of 1-3GHz, at the same also with
The host computer for being responsible for reconstructed image is docked, and mainly includes following components:
(a), it is responsible for the transmission of the logic level of electronic matrix switch module；By the incoming electricity of the logical sequence of host computer setting
Submatrix switch module is to control the low and high level switching of its hardware, so that controlling some microwave antenna carries out signal transmission and same
When control other microwave antennas carry out signal reception.
(b), power amplification acts on；For transmission signal to be amplified, the radiation intensity of signal is improved, microwave signal is promoted
Penetration depth.
(c), it is responsible for the down conversion process of radiofrequency signal, obtains the amplitude and phase information for receiving signal, and carries out modulus and turn
It changes for host computer processing.
In real work, host computer is acquired by data and transmission module is opened to microwave signal transceiver module and electronic matrix
It closes module and sends corresponding control signal, microwave signal transceiver module is worked.In the hair of microwave signal transceiver module
Port is penetrated, microwave electron signal is transferred to microwave antenna array port, microwave antenna transmitting by electronic matrix switch module
Microwave signal out, in the receiving port of microwave signal transceiver module, the microwave signal receiving end day of brain tissue's scattering
Line is received, and by electronic matrix switch module be passed to receiving port, according to electronic matrix switch module switch work when
Sequence completes the step, until the control sequential that host computer is transmitted is completed to acquire.At this point, host computer gives mechanical scanning rotating mould
Block transmission machine rotation instruction (including the instruction such as rotation speed, rotation stepping), mechanical motor will drive the rotation of microwave antenna array
Next angle is gone to, the working sequence of submatrix switch module of sending a telegram in reply of laying equal stress on repeats the above signal transmitting and receiving step until complete
The acquisition of microwave scattering data is completed.(more bases measurements and the physical location for changing microwave antenna) is operated by a series of,
The relationship capableing of between the precision of balanced microwave signal acquisition and system overall operation time.Host computer includes that image reconstruction is calculated
Method, the microwave scattering data that image reconstruction algorithm is obtained according to acquired in microwave antenna are thought using the algorithm of holographic Fourier transformation
Think, the spectrum information of microwave signal and space length information are constituted into corresponding relationship, to obtain because cerebral apoplexy leads to brain group
The spatial information that signal generates variation is knitted, the three-dimension space image of brain tissue is reconstructed, then according to the image of brain tissue
It can determine the position of the diseased region of patients with cerebral apoplexy and the type of lesion.Specifically, since human body different tissues have
Different electromagnetic properties, i.e. dielectric constant and conductivity, the difference of these parameters are also that microwave imaging can distinguish different tissues
The key factor of difference.After brain tissue generates lesion, the electromagnetic property different from normal tissue can be generated, brain function is extracted
After the electric constant of signal model, spectrum information can be formed, the algorithm idea of holographic Fourier transformation is recycled, by the frequency of signal
Spectrum information and space length constitute corresponding relationship, to obtain because of the space letter that cerebral apoplexy causes brain tissue signal to generate variation
Breath, reconstructs three-dimension space image, the preliminary image of patients with cerebral apoplexy brain available in this way.Because brain tissue is complicated
Property, the faint property of signal, reconstructed image necessarily includes unnecessary noise information.Therefore, image reconstruction algorithm utilizes computer
Noise reduction algorithm removes ambient noise, extracts this amount of the feature of image, carries out secondary image processing to reconstructed image, can be effective
Ground separates target object from background, finally constitutes the reconstructed image of the patients with cerebral apoplexy brain of high resolution, for suffering from
Person or medical staff test and analyze.
It is an a kind of specific embodiment process of the image reconstruction algorithm of brain imaging system in the present invention with reference to Fig. 4, Fig. 4
Figure, below illustrates image reconstruction algorithm:
1, host computer controls microwave antenna array by electronic matrix switch module and realizes more base measurements, microwave signal warp
After crossing brain tissue's scattering, microwave antenna array can get microwave scattering signal, and microwave antenna array is corresponded to covering surface
Product is on 36 positions in the grid (6*6) of 200mm*200mm, as shown in figure 5, Fig. 5 is a kind of brain imaging in the present invention
One specific embodiment position view of the microwave antenna array of system, microwave antenna array is with 36 microwave antennas in Fig. 5
Example, explanation below are also illustrated by taking 36 microwave antennas as an example.Microwave scattering signal include atmospheric reference reflection signal and
Signal is reflected in brain tissue, can obtain two groups of frequency domain datas, respectively E accordinglyXY(f) and BEXY(f), EXY(f) environment is indicated
With reference to reflectance data, BEXY(f) it indicates with the reflectance data under brain tissue's environment, with inverse fast fourier transform (IFFT)
By the frequency domain measurement E of aerial arrayXY(f) and BEXY(f) environment time-domain signal E is converted toXY(t) and brain tissue's time-domain signal
BEXY(t), wherein
EXY(t)=ifft (EXY(f)),
BEXY(t)=ifft (BEXY(f))。
2, according to environment time-domain signal EXY(t) and brain tissue's time-domain signal BEXY(t) the first calibration signal B is obtainedXY
(t), the first calibration signal BXYIt (t) is brain tissue's time-domain signal BEXY(t) with environment time-domain signal EXY(t) difference:
BXY(t)=BEXY(t)-EXY(t)。
3, in order to reduce environment and antenna coupled interference, host computer is to the first calibration signal BXY(t) denoising is carried out
To obtain the second calibration signal PXY(t), specific denoising method are as follows: showing 36 microwave antennas with microwave antenna array is
Example, to totally 36 B of 6*6 in the grid of Fig. 5XY(t) signal carries out every row handling averagely, by every row BXY(t) divided by this after being added
Capable data volume to get to equalization brain tissue's signal AX(t)；I.e.
N indicates the number of every row antenna, is herein definite value 6；Then AX(t) value is respectively A1(t)......A6(t)；
Then by each first calibration signal BXY(t) average brain tissue's signal A is subtractedX(t), the second calibration signal is obtained
PXY(t)；PXY(t)=BXY(t)-AX(t)；Obtain the second calibration signal P of one group of 6*6XY(t)。
4, microwave signal two-way time is obtained using synthetic focusing method；Specific acquisition methods are as follows:
(1) pixel is generated
In order to generate pixel at coordinate X, Y, the grid of usable floor area 300mm*300mm improves the resolution ratio of image,
As shown in fig. 6, Fig. 6 is an a kind of specific embodiment pixel position view of brain imaging system in the present invention；Such as Fig. 5 institute
Show, the position overlay area of microwave antenna is 200mm*200mm, in order to improve image resolution ratio, artificial setting pixel face
For product in the region of 300mm*300mm, the area of pixel can be larger or smaller, but excessive or too small, can cause figure
Image distortion or obscurity boundary.By taking 300mm*300mm as an example, then the position of microwave antenna is corresponded to from the region of 200mm*200mm
In the region of 300mm*300mm, it is equivalent to amplification.
(2) the round-trip distance from each microwave antenna position to each pixel is calculated
Each microwave antenna position X, the distance of Y to pixel are calculated with following formula:
Wherein, h is distance of the microwave antenna to cerebral haemorrhage point, xi、yjIt is the coordinate of pixel, microwave antenna position respectively
Setting coordinate is (X, Y), DXY(xi, yj) indicate that microwave antenna position (X, Y) arrives pixel (xi, yj) round-trip distance；Specifically,
It can use microwave radar antenna measurement and go out the different brain tissue blutpunkte of dielectric constant, the determination method of cerebral haemorrhage point is
The prior art repeats no more.
(3) microwave signal two-way time t is calculatedXY(xi,yj),
Wherein, c is microwave propagation speed, the i.e. light velocity；εrIt is the dielectric constant of propagation medium.
5, according to the second calibration signal PXY(t) and microwave signal two-way time tXY(xi,yj) obtain the strong of image slices vegetarian refreshments
Angle value；
Each pixel (xi, yj) intensity value i.e. be represented by
Wherein, r is the antenna number of each column microwave antenna；
C is the antenna number of every row microwave antenna；
I(xi,yj) it is pixel (xi, yj) intensity value.
6, brain image is reconstructed according to the intensity value of pixel.
So far, a kind of brain imaging system uses the integrated design of microwave signal Transmit-Receive Unit in the present invention, reduces
The volume of imaging system, while advanced three-dimensional imaging algorithm is used, accelerate the processing and analysis of imaging results, quick obtaining brain
The brain image of apoplexy patient reduces the cause of cerebral apoplexy to assist doctor quickly, effectively to carry out diagnoses and treatment to patients with cerebral apoplexy
Residual, lethality.
Embodiment 2
A kind of brain imaging method, comprising the following steps:
Microwave signal transceiving step using more bases measurement normal direction brain transmitting microwave signal and receives microwave scattering letter
Number；
Image-forming step, according to microwave scattering signal reconstruction brain image.
Using more bases measurement normal direction brain transmitting microwave signal and microwave scattering signal is received, is believed further according to microwave scattering
Number reconstruct brain image, overcomes that brain image acquisition methods are complicated in the prior art and are not easy the technical issues of realizing, quickly to obtain
Take the image of brain tissue；For patients with cerebral apoplexy, after the image for obtaining its brain tissue, doctor can be assisted to suffer from cerebral apoplexy
Person carries out diagnoses and treatment, reduces the disabling of patients with cerebral apoplexy, lethality.
Further, microwave scattering signal includes atmospheric reference reflection signal and brain tissue's reflection signal；Image-forming step
Include:
Time-domain signal obtains sub-step, reflects signal according to atmospheric reference and brain tissue's reflection signal acquisition is corresponding
Time-domain signal, corresponding time-domain signal are respectively environment time-domain signal and brain tissue's time-domain signal；
First calibration signal obtains sub-step, obtains the first calibration according to environment time-domain signal and brain tissue's time-domain signal
Signal, the first calibration signal are the difference of brain tissue's time-domain signal and environment time-domain signal；
Sub-step is denoised, denoising is carried out to the first calibration signal；
Microwave signal two-way time obtains sub-step, obtains microwave signal two-way time using synthetic focusing method；
Intensity value obtains sub-step, obtains the strong of image slices vegetarian refreshments according to the first calibration signal and microwave signal two-way time
Angle value；
Sub-step is imaged, brain image is reconstructed according to the intensity value of pixel.
Specific descriptions about microwave signal transceiving step and image-forming step please refer to the description in embodiment 1, no longer superfluous
It states.
Embodiment 3
A kind of brain imaging equipment, comprising:
At least one processor；And
The memory being connect at least one described processor communication；Wherein,
The memory is stored with the instruction that can be executed by least one described processor, and described instruction is by described at least one
A processor executes, so that at least one described processor is able to carry out the brain imaging method.About brain imaging side
The specific descriptions of method please refer to the description in embodiment 2, repeat no more.
Embodiment 4
A kind of computer readable storage medium, the computer-readable recording medium storage have computer executable instructions,
The computer executable instructions are used to that computer to be made to execute the brain imaging method.About the specific of brain imaging method
Description please refers to the description in embodiment 2, repeats no more.
It is to be illustrated to preferable implementation of the invention, but the invention is not limited to the implementation above
Example, those skilled in the art can also make various equivalent variations on the premise of without prejudice to spirit of the invention or replace
It changes, these equivalent deformations or replacement are all included in the scope defined by the claims of the present application.
Claims (10)
1. a kind of brain imaging method, which comprises the following steps:
Microwave signal transceiving step using more bases measurement normal direction brain transmitting microwave signal and receives microwave scattering signal；
Image-forming step, according to the microwave scattering signal reconstruction brain image.
2. brain imaging method according to claim 1, which is characterized in that the microwave scattering signal includes atmospheric reference
It reflects signal and signal is reflected in brain tissue；
The image-forming step includes:
Time-domain signal obtains sub-step, reflects signal according to the atmospheric reference and brain tissue reflection signal acquisition is opposite
The time-domain signal answered, respectively environment time-domain signal and brain tissue's time-domain signal；
First calibration signal obtains sub-step, obtains first according to the environment time-domain signal and brain tissue's time-domain signal
Calibration signal, first calibration signal are the difference of brain tissue's time-domain signal and the environment time-domain signal；
Microwave signal two-way time obtains sub-step, obtains microwave signal two-way time using synthetic focusing method；
Intensity value obtains sub-step, obtains image slices vegetarian refreshments according to first calibration signal and the microwave signal two-way time
Intensity value；
Sub-step is imaged, brain image is reconstructed according to the intensity value of the pixel.
3. brain imaging method according to claim 2, which is characterized in that the intensity value also wraps before obtaining sub-step
It includes:
Sub-step is denoised, denoising is carried out to first calibration signal.
4. a kind of brain imaging system characterized by comprising
Microwave signal Transmit-Receive Unit is believed for emitting microwave signal using more bases measurement normal direction brain and receiving microwave scattering
Number；
Imaging unit, for according to the microwave scattering signal reconstruction brain image.
5. brain imaging system according to claim 4, which is characterized in that the microwave scattering signal includes atmospheric reference
It reflects signal and signal is reflected in brain tissue；
The imaging unit includes:
Time-domain signal obtains module, for reflecting signal and brain tissue reflection signal acquisition phase according to the atmospheric reference
Corresponding time-domain signal, respectively environment time-domain signal and brain tissue's time-domain signal；
First calibration signal obtains module, for obtaining the according to the environment time-domain signal and brain tissue's time-domain signal
One calibration signal, first calibration signal are the difference of brain tissue's time-domain signal and the environment time-domain signal；
Microwave signal two-way time obtains module, for obtaining microwave signal two-way time using synthetic focusing method；
Intensity value obtains module, for obtaining image pixel according to first calibration signal and the microwave signal two-way time
The intensity value of point；
Image-forming module, for reconstructing brain image according to the intensity value of the pixel.
6. brain imaging system according to claim 5, which is characterized in that the imaging unit further include:
Module is denoised, for carrying out denoising to first calibration signal.
7. according to the described in any item brain imaging systems of claim 4 to 6, which is characterized in that the microwave signal transmitting-receiving is single
Member includes signal generating source, data acquisition and transmission module, microwave signal transceiver module, electronic matrix switch module and microwave day
Linear array, the output end of the signal generating source is acquired with the data and the input terminal of transmission module is connect, and the data are adopted
Collection and transmission module are all connected with the microwave signal transceiver module, the electronic matrix switch module, and the microwave signal is received
Hair module is connect with the electronic matrix switch module, and the electronic matrix switch module is connect with the microwave antenna array,
The imaging unit is acquired with the data and transmission module, the electronic matrix switch module are all connected with.
8. brain imaging system according to claim 7, which is characterized in that the microwave signal Transmit-Receive Unit further includes using
In the mechanical scanning rotary module of rotary microwave antenna, the microwave antenna array is connect with the mechanical scanning rotary module,
The imaging unit is connect with the mechanical scanning rotary module.
9. a kind of brain imaging equipment characterized by comprising
At least one processor；And
The memory being connect at least one described processor communication；Wherein,
The memory is stored with the instruction that can be executed by least one described processor, and described instruction is by described at least one
It manages device to execute, so that at least one described processor is able to carry out brain imaging side as described in any one of claims 1 to 3
Method.
10. a kind of computer readable storage medium, which is characterized in that the computer-readable recording medium storage has computer can
Execute instruction, the computer executable instructions for make computer execute brain as described in any one of claims 1 to 3 at
Image space method.
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