CN109340467B - Microfluidic pipeline, control method and manufacturing method of microfluidic pipeline - Google Patents
Microfluidic pipeline, control method and manufacturing method of microfluidic pipeline Download PDFInfo
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- CN109340467B CN109340467B CN201811211251.9A CN201811211251A CN109340467B CN 109340467 B CN109340467 B CN 109340467B CN 201811211251 A CN201811211251 A CN 201811211251A CN 109340467 B CN109340467 B CN 109340467B
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L9/00—Rigid pipes
- F16L9/17—Rigid pipes obtained by bending a sheet longitudinally and connecting the edges
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Abstract
The invention discloses a microfluidic pipeline, a control method and a manufacturing method of the microfluidic pipeline. The micro-fluidic pipeline comprises a pipe body and a fiber body; the fiber body comprises a first body and a second body along the length direction; the first body extends from the inner wall of the pipe body to the axial direction of the pipe body; the second body is provided with a head end and a tail end along the length direction, the head end is connected with the first body, and the second body can be switched between a first state and a second state; when the second body is in the first state, the tail end is positioned at one side of the head end, which is close to the axis; when the second body is in the second state, the tail end is positioned at one side of the head end, which is far away from the axis; the first and second bodies have different hydrophilicity and hydrophobicity. According to the invention, the first body and the second body with different hydrophily and hydrophobicity are arranged, and the second body can be switched between the first state and the second state, so that the hydrophily and hydrophobicity of the inner wall surface of the microfluidic pipeline is changed, and the flow of water or water-containing liquid in the microfluidic pipeline is controlled.
Description
Technical Field
The application relates to the field of microfluidics, in particular to a microfluidic pipeline, a control method of the microfluidic pipeline and a manufacturing method of the microfluidic pipeline.
Background
Microfluidics is a system that processes or manipulates minute fluids of nanoliter to picoliter volume using microchannels of tens to hundreds of microns in size. At present, the flow of water in a pipeline is not easy to control under a micro-scale environment.
Disclosure of Invention
The embodiment of the invention provides a micro-fluidic pipeline and a manufacturing method thereof, which can control water to flow in a pipe body.
According to a first aspect of embodiments of the present invention, a microfluidic channel is provided. It comprises a tube body and a fiber body;
the fibrous body comprises a first body and a second body along the length direction;
the first body extends from the inner wall of the pipe body to the axial direction of the pipe body, and one end, far away from the second body, of the first body is fixedly connected to the inner wall;
the second body is provided with a head end and a tail end along the length direction, the head end is connected with the first body, and the second body can be switched between a first state and a second state;
when the second body is in the first state, the tail end is positioned on one side of the head end close to the axis; when the second body is in the second state, the tail end is positioned on the side of the head end away from the axis;
the first body and the second body have different hydrophilicity and hydrophobicity.
Preferably, when the second body is in the second state, the fiber body is bent to form a break point close to the axis, and the break point is disposed on the first body.
Preferably, when the second body is located in the second state, the second body extends from the head end to the tail end in a direction away from the axial direction.
Preferably, the ratio of the length of the first body to the length of the second body is greater than 1; a ratio of a length of the first body to a length of the second body is greater than 3 and less than 8.
Preferably, the fibrous body quantity is a plurality of, a plurality of the fibrous body evenly set firmly in the inner wall of body.
Preferably, the second body has magnetism, or the second body and at least a part of the first body close to the second body have magnetism; so that under the action of magnetic force, the second body is switched between the first state and the second state.
Preferably, the first body is a hydrophilic material, and the second body is a hydrophobic material; or, the first body is made of hydrophobic material, and the second body is made of hydrophilic material.
Preferably, the ratio of the inner diameter of the tubular body to the length of the fibrous body is greater than 10.
According to a second aspect of the embodiments of the present invention, there is provided a method for controlling a microfluidic channel, the method being used for changing a state of a second body of the microfluidic channel, the microfluidic channel including an inlet and an outlet, the method comprising: the state of the second body is sequentially changed in a direction from the inlet to the outlet.
Preferably, the first body is a hydrophobic material, and the second body is a hydrophilic material;
when the first body is in the initial state, the second body is in the first state; the second body is sequentially changed from the first state to the second state in a direction from the inlet to the outlet.
Preferably, the second body has magnetism; the state of the second body is changed by changing the magnetic field outside the microfluidic channel.
According to a third aspect of the embodiments of the present invention, there is provided a method for manufacturing a microfluidic channel, including the steps of:
fixing a fiber body on the surface of the wall plate;
coating a magnetic solution on one end of the fiber body far away from the wallboard; and rendering the end of the fibrous body remote from the wall panel hydrophilic;
crimping the panel to form a tubular structure.
Preferably, the wall plate is an elastic substrate.
Preferably, the UV light irradiates an end of the fibrous body remote from the wall plate to make it hydrophilic.
The positive progress effects of the invention are as follows:
the invention provides a liquid crystal display device, which is provided with a first body and a second body which are different in hydrophilicity or hydrophobicity and can be switched between a first state and a second state. The water flows in the microfluidic pipeline and contacts one end of the fiber body close to the axis of the pipe body, namely the water can contact the first body or the second body, and the flow of the water in the microfluidic pipeline can be controlled because the first body and the second body have different hydrophilicity and hydrophobicity.
Drawings
Fig. 1 is a schematic structural diagram of a microfluidic channel according to a preferred embodiment of the present invention.
Fig. 2 is a schematic structural diagram of another view angle of the microfluidic channel according to the preferred embodiment of the present invention, when the second body is in the first state.
Fig. 3 is a schematic structural diagram of a microfluidic channel according to a preferred embodiment of the present invention, in which the second body is in a second state.
Fig. 4 is a simplified flow chart of a method for manufacturing a microfluidic channel according to a preferred embodiment of the present invention.
Fig. 5 is a partial schematic flow chart of a method for manufacturing a microfluidic channel according to a preferred embodiment of the present invention.
Description of the reference numerals
Head end 221
Receiving tank 500
Detailed Description
Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present invention. Rather, they are merely examples of apparatus and methods consistent with certain aspects of the invention, as detailed in the appended claims.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
It should be understood that the terms "first," "second," and the like as used in the description and in the claims, do not denote any order, quantity, or importance, but rather are used to distinguish one element from another. Also, the use of the terms "a" or "an" and the like do not denote a limitation of quantity, but rather denote the presence of at least one. Unless otherwise indicated, "front", "rear", "lower" and/or "upper" and the like are for convenience of description and are not limited to one position or one spatial orientation. The word "comprising" or "comprises", and the like, means that the element or item listed as preceding "comprising" or "includes" covers the element or item listed as following "comprising" or "includes" and its equivalents, and does not exclude other elements or items. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect. The present invention will be described in detail below with reference to the accompanying drawings. The features of the following examples and embodiments may be combined with each other without conflict.
As shown in fig. 1 to 3, the present invention discloses a microfluidic channel 10. The microfluidic control tube includes a tube body 100 and a fiber body 200. In fig. 2 and 3, the tubular body 100 is in an expanded shape, but the tubular body 100 is actually a tubular structure.
The fibrous bodies 200 are a plurality of, and a plurality of fibrous bodies 200 are evenly fixed in the tube 100, and one end of the fibrous body 200 is fixed in the inner wall 101 of the tube 100. As shown, one end of the fibrous body 200 near the axis of the tube body 100 forms an inner wall surface 102 of the microfluidic channel 10. When water or a liquid containing water flows in the microfluidic channel 10, the liquid contacts the inner wall surface 102 formed by the fibrous body 200, so that the hydrophilicity or hydrophobicity of the fibrous body 200 can control the flow of the liquid in the microfluidic channel 10.
As shown in fig. 2, the fiber body 200 includes a first body 210 and a second body 220 having different hydrophilicity or hydrophobicity along the length direction L. In the present embodiment, the first body 210 has hydrophobicity, and the second body 220 has hydrophilicity. Of course, the first body 210 may have a hydrophilic property, and the second body 220 may have a hydrophobic property.
The first body 210 extends from the inner wall 101 of the tube 100 to the axial direction of the tube 100, and one end of the first body 210 away from the second body 220 is fixedly connected to the inner wall 101.
As shown in fig. 2 and 3, the second body 220 has a head end 221 and a tail end 222 along a length direction, the head end 221 is connected with the first body 210, and the second body 220 is convertible between a first state 223 and a second state 224. When the second body 220 is in the first state 223, the tail end 222 is located on the side of the head end 221 near the axis. When the second body 220 is in the second state 224, the tail end 222 is located on the side of the head end 221 away from the axis. That is, when the second body 220 is in the second state 224, the second body 220 is bent away from the axis.
In the present embodiment, when the second body 220 is in the first state 223, the second body 220 having hydrophilicity forms the inner wall surface 102 of the microfluidic channel 10, and the microfluidic channel 10 has hydrophilicity. At this time, water or a liquid containing water can more smoothly enter the microfluidic channel 10. Meanwhile, water or a liquid containing water in the microfluidic channel 10 is more easily adsorbed to the inner wall surface 102 of the microfluidic channel 10, i.e., is not easily flowed in the microfluidic channel 10. When the second body 220 is in the second state 224, the inner wall surface 102 of the microfluidic channel 10 is formed by the first body 210 having hydrophobicity, and the microfluidic channel 10 has hydrophobicity. At this time, water or a liquid containing water cannot easily enter the microfluidic channel 10. Meanwhile, water or a liquid containing water in the microfluidic channel 10 is not easily adsorbed to the inner wall surface 102 of the microfluidic channel 10, i.e., the water or the liquid can smoothly flow in the microfluidic channel 10. When the second bodies 220 of the fibrous bodies 200 in the microfluidic channels 10 are not in the same state, part of the microfluidic channels 10 has hydrophilicity and part has hydrophobicity. When water or liquid containing water is located in the microfluidic channel 10, the hydrophobic microfluidic channel 10 generates repulsive force to the liquid, and pushes the liquid drop to the hydrophilic microfluidic channel 10, so as to accelerate the liquid to flow in the microfluidic channel 10. Of course, when the second body 220 is in the second state 224, the inner wall surface 102 may also be formed by a portion of the second body 220. At this time, the second body 220 has a larger bending range with respect to the first state 223, and the inner diameter of the microfluidic channel 10 is larger than that when the second body 220 is in the first state 223, so that water or a liquid containing water can flow through the microfluidic channel more smoothly when the second body 220 is in the second state 224 than in the first state 223.
Of course, in other embodiments, i.e., when the first body 210 has hydrophilicity and the second body 220 has hydrophobicity. When the second body 220 is in the first state 223, water or liquid containing water in the microfluidic channel 10 is not easily adsorbed on the inner wall surface 102 of the microfluidic channel 10, i.e., the water or liquid can smoothly flow in the microfluidic channel 10. When the second body 220 is in the second state 224, water or a liquid containing water in the microfluidic channel 10 is easily absorbed to the inner wall surface 102 of the microfluidic channel 10 and is not easily flowed in the microfluidic channel 10.
Preferably, when the second body 220 is in the second state 224, the fiber body 200 is bent to form a bending point 201 close to the axis, and the bending point 201 is disposed on the first body 210. The end of the fibrous body 200 away from the inner wall 101 of the tube 100 forms the inner wall surface 102 of the microfluidic channel 10, i.e. the break point 201 of the fibrous body 200 forms the inner wall surface 102 of the microfluidic channel 10, and the hydrophilicity or hydrophobicity at the break point 201 determines the hydrophilicity or hydrophobicity of the microfluidic channel 10. That is, when the second body 220 is in the second state 224, the inner wall surface 102 of the microfluidic channel 10 is formed only by the first body 210 having hydrophobicity. With this arrangement, the hydrophilicity and hydrophobicity of the microfluidic channel 10 can be changed by changing the state of the second body 220, thereby facilitating control of the flow of water or a liquid containing water in the channel.
When the second body 220 is in the second state 224, the second body 220 extends from the head end 221 to the tail end 222 in a direction away from the axis. Through such an arrangement, when the second body 220 is in the second state 224, that is, when the bent portion of the second body 220 can extend into the gap between two adjacent first bodies 210, the second body 220 does not cover one end of the adjacent first body 210 facing the axis when bent, so that the outer surface of the second body 220 forms the inner wall surface 102, and thus the hydrophilicity or hydrophobicity of the inner wall surface 102 cannot be changed.
When water or a liquid containing water needs to be sucked into the microfluidic channel 10, the second body 220 is in the first state 223, and the second body 220 having hydrophilicity can adsorb the liquid and suck the liquid into the microfluidic channel 10; or when water or liquid containing water is required to slowly flow in the microfluidic pipeline 10, the second body 220 is in the first state 223, that is, the second body 220 forms the inner wall surface 102 of the microfluidic pipeline 10, so that the liquid is more easily adsorbed on the inner wall surface 102 formed by the hydrophilic second body 220, the viscosity coefficient of the liquid in the flow process is enhanced, and the liquid is not easy to flow in the microfluidic pipeline. When water or liquid containing water rapidly flows in the microfluidic channel 10, the second body 220 is in the second state 224, that is, the second body 220 is bent, and the first body 210 forms the inner wall surface 102 of the microfluidic channel 10, so that the liquid is not easily adsorbed on the inner wall surface 102 formed by the hydrophobic second body 220, the viscosity coefficient of the liquid in the flowing process is reduced, and the liquid smoothly flows in the microfluidic channel.
In addition, a ratio of the length of the first body 210 to the length of the second body 220 is greater than 1. With this arrangement, when the second body 220 is in the second state 224, the second body 220 can be located in the gap of the first body 210, so that the hydrophilicity or hydrophobicity of the second body 220 does not affect the hydrophilicity or hydrophobicity of the inner wall surface 102. Preferably, the ratio of the length of the first body 210 to the length of the second body 220 is greater than 3 and less than 8, and in order to clearly show the structure of the first body 210 and the second body 220 in the drawings, the ratio of the length of the first body 210 to the length of the second body 220 of each fibrous body 200 in the drawings does not fully satisfy the requirement of greater than 3 and less than 8. By such an arrangement, when the second body 220 is in the second state 224, the second body 220 can be entirely disposed in the gap between two adjacent first bodies 210. Also, in the present embodiment, the ratio of the inner diameter of the tube 100 to the length of the fiber body 200 is greater than 10, and thus a flowing space is provided for the liquid in the microfluidic channel 10. In order to clearly show the connection relationship between the fiber body and the tube body, fig. 1 shows that the ratio of the inner diameters of the fiber body 200 and the tube body 101 does not satisfy a ratio of more than 10.
In the present embodiment, the second body 220 has magnetism. The second body 220 is switchable between a first state 223 and a second state 224 under the influence of a magnetic force. When no external magnetic field is applied around the microfluidic channel 10, the second body 220 is not bent, that is, the second body 220 is in the first state 223, and the second body 220 extends from the head end 221 to the tail end 222 in a radial direction of the microfluidic channel 10 toward the axis. The end surface of the second body 220 away from the tube 100 forms the inner wall surface 102 of the microfluidic channel 10, so the inner wall surface 102 of the microfluidic channel 10 has hydrophilicity. As shown in fig. 3, the magnet 400 is disposed around the tube 100, the magnet 400 forms a magnetic field around the microfluidic channel 10, the second body 220 is bent, that is, the second body 220 is converted into the second state 224, the tail end 222 is located on the side of the head end 221 away from the axis, meanwhile, any one second body 220 is disposed in the gap between two adjacent first bodies 210, the end surface of the inner wall 101 of the first body 210 away from the tube 100 forms the inner wall surface 102 of the microfluidic channel 10, and therefore the inner wall surface 102 of the microfluidic channel 10 has hydrophobicity.
Of course, at least a portion of the first body 210 near the second body 220 may also have magnetism, i.e., the second body 220 and at least a portion of the first body 210 near the second body 220 have magnetism. At this time, when there is no external magnetic field around the microfluidic channel 10, the first body 210 and the second body 220 have the same configuration as described above. When a magnetic field is applied around the microfluidic channel 10, the second body 220 and the magnetic portion of the first body 210 are bent together, i.e. the second body 220 is transformed into the second state 224. Through the arrangement, the fiber body 200 is bent to form a bending point 201 close to the axis and is positioned on the first body 210, the second body 220 and a part of the first body 210 are arranged in the gap between two adjacent first bodies 210, and the inner wall surface 102 of the microfluidic pipeline 10 is at least part of the first body 210. The inner wall surface 102 of the microfluidic channel 10 is ensured to have hydrophobicity.
The invention also discloses a control method of the microfluidic pipeline. The control method can change the state of the second body 220 of the microfluidic channel 10, and the microfluidic channel 10 includes an inlet and an outlet along the axial direction, and the state of the second body 220 is changed sequentially along the direction from the inlet to the outlet. The hydrophilicity and hydrophobicity of the microfluidic channel 10 can be changed by changing the state of the second body 220, that is, the states of the second bodies 220 in the microfluidic channel 10 can be changed in sequence, so that all the second bodies 220 in the microfluidic channel 10 can have two states at the same time, and the microfluidic channel 10 can also have hydrophilicity or hydrophobicity in different regions.
In this embodiment, the first body 210 is made of a hydrophobic material, and the second body 220 is made of a hydrophilic material. When in the initial state, the second bodies 220 of the microfluidic channels 10 are all in the first state 223, i.e. the microfluidic channels 10 are hydrophilic, and water or a liquid containing water can easily enter the microfluidic channels 10. Thereafter, the second body 220 is sequentially changed from the first state 223 to the second state 224 in a direction along the inlet to the outlet. I.e. the sequential switching from hydrophilic to hydrophobic in the microfluidic channel 10 in the inlet-to-outlet direction. At this time, the second body 220 close to the inlet is in the second state 224, the part of the microfluidic channel 10 has hydrophobicity, the contact angle of the liquid with the inner wall surface 102 having hydrophobicity is increased, and the adhesiveness is reduced, that is, the microfluidic channel 10 close to the inlet generates a repulsive force to the liquid. While the second body 220 near the outlet is in the first state 223, the portion of the microfluidic channel 10 that is hydrophilic and has good adhesion to the liquid, and the inner wall surface 102 near the outlet creates an attractive force on the liquid, thus forcing the liquid to flow toward the outlet. In this way, the flow of liquid in the microfluidic channel 10 is accelerated.
Preferably, the second body 220 has magnetism; by changing the magnetic field outside the microfluidic channel 10, the state of the second body 220 is changed. The magnetic field can be dynamically adjusted by an external electric field, such that the second body 220 is dynamically switched between the first state 223 and the second state 224. Of course, the microfluidic channel 10 may be divided into a plurality of regions along the direction from the inlet to the outlet, the hydrophilicity and hydrophobicity of each region may be changed by controlling the state of the second body 220 in the plurality of regions respectively through the variable magnetic field, and the water or the liquid containing water is subjected to repulsive and attractive forces applied to the liquid by the different regions due to the change in the hydrophilicity and hydrophobicity of the microfluidic channel 10, so that the liquid flows. To achieve such an objective, the magnetic field outside the microfluidic channel 10 needs to be independently controlled in different regions, so as to achieve real-time dynamic switching between the first state 223 and the second state 224 of the second body 220 located in different regions of the microfluidic channel 10. Of course, the magnet 400 may be disposed outside the microfluidic channel 10, and the state of the second body 220 may be sequentially changed by moving the magnet 400 disposed outside the microfluidic channel 10 in a direction from the inlet to the outlet.
As shown in fig. 4 and 5, the present invention further discloses a method for manufacturing the microfluidic channel 10, wherein the method for manufacturing the microfluidic channel 10 can manufacture a manufacturing method capable of changing the hydrophilicity or hydrophobicity of the inner wall surface 102 of the microfluidic channel 10, and the manufacturing method includes steps 1000, 2000 and 3000.
Wherein, as shown in fig. 4 and part (a) of fig. 5, step 1000: the fiber body 200 is fixed to the surface of the wall plate 300. Wherein a plurality of fiber bodies 200 are uniformly and fixedly arranged on the wall plate 300, and the fiber bodies 200 are densely arranged on the surface of the wall plate 300.
As shown in fig. 4, part (b) of fig. 5, and part (c) of fig. 5, step 2000: coating a magnetic solution on one end of the fiber body 200 away from the wall plate 300; and makes the end of the fibrous body 200 remote from the wall plate 300 hydrophilic. In this embodiment, the end of the fiber body is immersed in the holding tank 500 containing the magnetic solution. The magnetic solution may be a liquid containing a magnetic ionic liquid.
Step 3000: crimping wall panel 300 into a tubular configuration as shown in fig. 1, so that wall panel 300 becomes tubular body 100. The wall plate 300 is an elastic substrate, and may be made of Polydimethylsiloxane (PDMS), Polyurethane (PU) and polyurethane acrylate (PUA). With this arrangement, the wall plate 300 can be easily rolled to form the tubular body 100. At this time, an end of the fibrous body 200 away from the wall plate 300, that is, an end of the inner wall 101 of the tube 100 forms an inner wall surface 102 of the microfluidic channel 10.
In this embodiment, the end of the fiber body 200 away from the wall plate 300 is made hydrophilic by irradiating UV light on the end of the fiber body 200 away from the wall plate 300 to form a polymer film on the end of the fiber body 200 away from the wall plate 300, wherein the polymer film has hydrophilicity. Of course, the end of the fiber body 200 away from the wall plate 300 may be made hydrophilic in other ways. The second body 220 is formed at the end of the fibrous body 200 having hydrophilicity, and the first body 210 is formed at the end of the fibrous body having no hydrophilicity. The surface of the second body 220 is coated with the magnetic solution, the surface of the first body 210 may not be coated with the magnetic solution, and when the fiber body 200 is subjected to the action force of the magnetic field force, the second body 220 is only bent. The second body 220 is bent in a direction away from the axis and forms a bending point 201 on the fiber body 200, the bending point 201 may be located at a connection position between the second body 220 and the first body 210, or the second body 200 drives the first body 210 connected with the second body 220 to bend together when bending occurs, so that the bending point 201 is located on the first body 210. Of course, the surface of the second body 220 may be coated with the magnetic solution, at least a portion of the first body 210 is coated with the magnetic solution, and the portion of the first body 210 coated with the magnetic solution is a portion of the first body 210 close to the second body 220. When the fibrous body 200 is subjected to the action force of the magnetic field force, the second body 220 and a part of the first body 210 are bent, and a folding point 201 is formed on the fibrous body 200, wherein the folding point 201 is located on the first body 210. At this time, the break point 201 is an end of the fiber body 200 away from the wall plate 300, and forms the inner wall surface 102 of the microfluidic channel 10. The hydrophilicity and hydrophobicity at the break point 201 determines the hydrophilicity and hydrophobicity of the microfluidic channel 10.
Although the present invention has been described with reference to a preferred embodiment, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.
The disclosure of this patent document contains material which is subject to copyright protection. The copyright is owned by the copyright owner. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure, as it appears in the patent and trademark office official records and records.
Claims (15)
1. A microfluidic channel, comprising a tube body and a fibrous body;
the fibrous body comprises a first body and a second body along the length direction;
the first body extends from the inner wall of the pipe body to the axial direction of the pipe body, and one end, far away from the second body, of the first body is fixedly connected to the inner wall;
the second body is provided with a head end and a tail end along the length direction, the head end is connected with the first body, and the second body can be switched between a first state and a second state;
when the second body is in the first state, the tail end is positioned on one side of the head end close to the axis; when the second body is in the second state, the tail end is positioned on the side of the head end away from the axis;
the first body and the second body have different hydrophilicity and hydrophobicity.
2. The microfluidic channel of claim 1, wherein the fiber body bends to form a break point near the axis when the second body is in the second state, the break point being disposed on the first body.
3. The microfluidic channel of claim 2, wherein the second body extends away from the axis from the head end to the tail end when the second body is in the second state.
4. The microfluidic channel of claim 1, wherein a ratio of a length of the first body to a length of the second body is greater than 1.
5. The microfluidic channel of claim 4, wherein a ratio of the length of the first body to the length of the second body is greater than 3 and less than 8.
6. The microfluidic channel of claim 1, wherein the number of the fiber bodies is multiple, and the multiple fiber bodies are uniformly and fixedly arranged on the inner wall of the tube body.
7. The microfluidic channel of claim 1, wherein the ratio of the inner diameter of the tubular body to the length of the fibrous body is greater than 10.
8. The microfluidic channel of claim 1, wherein the second body is magnetic or at least portions of the second body and the first body adjacent to the second body are magnetic such that the second body is switchable between the first state and the second state by a magnetic force.
9. The microfluidic channel of any of claims 1-8, wherein the first body is a hydrophilic material and the second body is a hydrophobic material; or, the first body is made of hydrophobic material, and the second body is made of hydrophilic material.
10. A method of controlling a microfluidic channel for changing the state of a second body of the microfluidic channel according to any of claims 1 to 7, wherein the microfluidic channel comprises an inlet and an outlet, the method comprising: the state of the second body is sequentially changed in a direction from the inlet to the outlet.
11. The method of claim 10, wherein the first body is a hydrophobic material and the second body is a hydrophilic material;
when the first body is in the initial state, the second body is in the first state; the second body is sequentially changed from the first state to the second state in a direction from the inlet to the outlet.
12. The method of claim 10, wherein the second body is magnetic; the state of the second body is changed by changing the magnetic field outside the microfluidic channel.
13. A method of fabricating a microfluidic channel according to any of claims 1-9, comprising the steps of:
fixing a fiber body on the surface of the wall plate;
coating a magnetic solution on one end of the fiber body far away from the wallboard, and enabling the end of the fiber body far away from the wallboard to have hydrophilicity;
crimping the panel to form a tubular structure.
14. The method of claim 13, wherein the panel is a flexible substrate.
15. The method of claim 13 wherein UV light irradiates an end of the fibrous body remote from the wall panel to render it hydrophilic.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101553680A (en) * | 2006-09-21 | 2009-10-07 | 浦项工科大学校产学协力团 | Method for fabricating solid body having superhydrophobic surface structure and superhydrophobic tube using the same method |
| CN103127971A (en) * | 2011-12-02 | 2013-06-05 | 国家纳米科学中心 | Micro-flow pipe and preparation method |
| CN107971049A (en) * | 2017-09-29 | 2018-05-01 | 京东方科技集团股份有限公司 | Micro-fluidic chip and its driving method, micro-fluidic device and biology sensor |
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| JP2001346866A (en) * | 2000-06-06 | 2001-12-18 | Naisemu:Kk | Hybrid resin material and its manufacturing method |
| US20090137043A1 (en) * | 2007-11-27 | 2009-05-28 | North Carolina State University | Methods for modification of polymers, fibers and textile media |
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| CN101553680A (en) * | 2006-09-21 | 2009-10-07 | 浦项工科大学校产学协力团 | Method for fabricating solid body having superhydrophobic surface structure and superhydrophobic tube using the same method |
| CN103127971A (en) * | 2011-12-02 | 2013-06-05 | 国家纳米科学中心 | Micro-flow pipe and preparation method |
| CN107971049A (en) * | 2017-09-29 | 2018-05-01 | 京东方科技集团股份有限公司 | Micro-fluidic chip and its driving method, micro-fluidic device and biology sensor |
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