CN109331338A - The double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker and method - Google Patents

The double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker and method Download PDF

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CN109331338A
CN109331338A CN201811520752.5A CN201811520752A CN109331338A CN 109331338 A CN109331338 A CN 109331338A CN 201811520752 A CN201811520752 A CN 201811520752A CN 109331338 A CN109331338 A CN 109331338A
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signal
ventricle
ventricular pressure
circuit
processing unit
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王文硕
丛硕
魏来
王春生
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Zhongshan Hospital Fudan University
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Zhongshan Hospital Fudan University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/37Monitoring; Protecting
    • A61N1/3718Monitoring of or protection against external electromagnetic fields or currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/37Monitoring; Protecting
    • A61N1/3702Physiological parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/37Monitoring; Protecting
    • A61N1/371Capture, i.e. successful stimulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Electromagnetism (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The invention discloses a kind of double sensory perceptual systems of the ventricle of Implanted cardiac pacemaker electricity-ventricular pressure and methods.The system comprises magnetic field signal processing units, and artificial or spontaneous magnetic field strength is converted to logical signal and is input in central processing unit;Ventricle electricity aware circuit provides the perception of ventricular electrical signal, handles and be transferred to central processing unit;Ventricular pressure aware circuit provides the perception of ventricular pressure signal, handles and be transferred to central processing unit;Central processing unit is responsible for switching perception pacing mode program, and is interacted with pacemaker microprocessor;Under artificial or spontaneous high interference of electromagnetic field scene, this system magnetic field signal processing unit can know with automatic sensing changes of magnetic field and by pacing mode by ventricle inductance-ventricular pacing mode is switched to ventricular pressure perception-ventricular pacing mode, the effectively perceive and demand pacing to heart movement are maintained by ventricular pressure signal, the stabilization for guaranteeing cardiac hemodynamic, to greatly improve operation safety.

Description

The double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker and method
Technical field
The invention belongs to the field of medical instrument technology, and in particular to a kind of ventricle electricity-ventricle of Implanted cardiac pacemaker Press double sensory perceptual systems and method.
Background technique
The pacemaker (cardiac pacemaker) of implanted is that one kind is implanted in the intracorporal electronic therapy of people and sets It is standby.Pacemaker perceives the electrical activity of human heart itself by the electrode cable of implantation and evaluates heart itself working condition, Starting impulse generator when noting abnormalities generates low energy electric pulse stimulation heart and is allowed to that excitement and conduction function occurs, with mould The impulsion of pseudocardia occurs and the electrophysiological functions such as conduction, plays the mesh for treating certain arrhythmia caused cardiac dysfunctions 's.
With the continuous development and raising of Cardiac Pacing, the patient of more and more arrhythmia cordis receives cardiac pacing The treatment of device, the patient that permanent pacemaker is carried in surgical operation are also further common.However, being widely applied in surgical operation Electric knife, pacemaker can be caused greatly to interfere.Electric knife occurs by high-frequency electronic arc discharge in organism surface Extremely strong current density, makes bio-tissue be dispersed by Explosive evaporation, to achieve the purpose that cut tissue in surgical operation. The high-frequency current generated when its work will lead to pacemaker and perception disorder occurs, influence normally to pace work, induces patient and dislikes Property arrhythmia cordis, the ventricular fibrillation even serious consequences such as cardiac arrest.
Currently, for the patient for carrying Implanted cardiac pacemaker for needing to carry out surgical operation, in addition to during surgery It reduces the frequency of use of electric knife to the greatest extent, is used cooperatively ultrasound knife, reinforce in art outside safety nursing, most important measure is to use Magnet opens or closes the reed switch for being used to switch pacemaker mode of cardiac pacing, pacemaker by perception mode of cardiac pacing or its His program-controlled demand pacing mode is fixed frequency ventricular pacemaking mode, to guarantee beating and the protection pacemaker of patient's heart in art Perceptional function is without damage, and restores original mode pace-making after surgery.
Although above method can perform the operation to avoid electric knife to the interference of pace-making perception and the inhibition of pacemaker impulse Anesthesia start, entire operative process until again by pacemaker pattern recovery to preoperative operating mode be up to a few hours it In, pacemaker paces patient's heart by default fixed frequency ventricular pacing mode, can not perceive intrinsic ventricular telecommunications Number, this may cause competitive cardiac rhythm, induces arrhythmia cordis, causes irreversible damage to heart, and influence haemodynamics, seriously Person can jeopardize patient vitals.
At the same time, when patient is under powerful magnetic field environment, electrical effect caused by magnetic field can severe jamming pace-making Perception of the device to patient's ventricular electrical signal;And because of the presence in magnetic field, the reed of the pacemaker for switching ventricular electrical signal Switch possibly can not it is normally-open or close, cause pacemaker cannot normally perceive ventricular electrical signal and provide pulse, equally The malignant arrhythmia or cardiac arrest that patient may be caused, jeopardize patient vitals.
Summary of the invention
In view of the above drawbacks of the prior art, the present invention provides a kind of ventricle electricity-ventricle of Implanted cardiac pacemaker Press double sensory perceptual systems.Under artificial or spontaneous high interference of electromagnetic field scene, the processing of this system magnetic field signal is single for the invention Member can know with automatic sensing changes of magnetic field and by pacing mode by ventricle inductance-ventricular pacing mode is switched to ventricular pressure perception- Ventricular pacing mode maintains to overcome traditional pace-making to the effectively perceive and demand pacing of heart movement by ventricular pressure signal The competitive cardiac rhythm that device is likely to occur in this scenario with fixed frequency ventricular pacemaking, and arrhythmia cordis is induced, heart is caused not The phenomenon that reversible damage, guarantee the stabilization of cardiac hemodynamic, to greatly improve operation safety.Meanwhile the present invention mentions The double sensory perceptual systems of ventricle electricity-ventricular pressure out can cancel original pacemaker reed design, avoid using electric knife Surgical operation and the interference scenes such as high electromagnetic field under, reed switch possibly can not be normally-open or close, and lead to pacemaker not Ventricular electrical signal can normally be perceived and provide pulse, effective protection patient equipped with heart pacemaker.
Above-mentioned purpose of the invention is achieved through the following technical solutions:
A kind of double sensory perceptual systems of the ventricle electricity of Implanted cardiac pacemaker-ventricular pressure signal characterized by comprising magnetic Field signal processing unit is used for external magnetic field receptor, artificial or spontaneous magnetic field strength is converted to logical signal;The heart Room electricity aware circuit obtains the signal of ventricle electricity and carries out signal processing for the electrode terminal of external pacemaker;Ventricle pressure sensitivity Know circuit, is used for external pressure sensor, obtains the signal of ventricular pressure and carry out signal processing;Central processing unit, one letter Number end for connecting pacemaker microprocessor, remaining corresponding signal end is separately connected the magnetic field signal processing unit, ventricular pressure Aware circuit, ventricle electricity aware circuit receive the logical signal of magnetic field signal processing unit, the heart that ventricle electricity aware circuit provides The ventricular pressure signal that room electric signal and ventricular pressure aware circuit provide, and interacted with pacemaker microprocessor, it is responsible for switching perception Pacing mode is that ventricle inductance knows that pacing mode or ventricular pressure perceive pacing mode.
Further, the central processing unit includes: including perceiving pacing mode decision module, status register, instruction Register, communication module, the status register receive and store magnetic field letter for connecting the magnetic field signal processing unit The logical signal of number processing unit output is converted into the logic signal value of digital signal by analog signal;Described instruction register, The corresponding signal end of one end and perception pacing mode decision module is bi-directionally connected, and determines mould for storing from perception pacing mode The logical order value of block sending is simultaneously exported to communication module, while logical order value is fed back to perception pace-making mould with fixed frequency Formula decision module;The perception pacing mode decision module, one signal input part connect the output end of the status register, Remaining corresponding signal end is connected respectively ventricular pressure aware circuit, ventricle electricity aware circuit;For being connect to from command register It is corresponding that the logical order value that receives and the logic signal value transmitted from status register carry out unification, and by the logic after correspondence Instruction value is exported together with corresponding ventricular electrical signal or ventricular pressure signal to communication module;The communication module, two signal Output end of the end respectively with the output end of the perception pacing mode decision module, command register is correspondingly connected with, for obtaining Logical order value and corresponding ventricular electrical signal or ventricular pressure signal, another signal end are micro- for being bi-directionally connected the pacemaker The corresponding signal end of processor, for realizing the communication between central processing unit and pacemaker microprocessor.
Further, when the magnetic field strength is greater than the threshold value of setting, the logic signal value of status register is 1;Magnetic When field intensity is less than the threshold value of setting, the logic signal value of status register is 0.
Further, the logical order value is corresponding with the unification of the logic signal value, if referring to command register Logical order value it is consistent with the logic signal value of status register, then keep the logical order value of command register constant, if The logical order value of command register and the logic signal value of status register are inconsistent, then the logic for updating command register refers to Enable value.
Further, when the logical order value of described instruction register is 1, the signal of ventricle electricity aware circuit is interrupted, is opened With the signal of ventricular pressure aware circuit;When instruction value is 0, the signal of ventricular pressure aware circuit is interrupted, ventricle inductance is enabled and knows electricity The signal on road.
Further, the communication module uses Universal Serial Interface SPI protocol, master-slave mode, based on central processing unit Machine, pacemaker microprocessor are slave.
Further, the ventricle electricity aware circuit includes ventricle electrofiltration wave circuit, the electrically amplified circuit of ventricle, ventricle electricity mould Number converter, the ventricle electrofiltration wave circuit, the electrode terminal of external pacemaker are simultaneously electrically connected with the electrically amplified circuit of ventricle, are used for Output gives ventricle electrically amplified circuit after carrying out filtering clutter from the analog signal of the collected ventricle electricity of electrode terminal;The heart The electrically amplified circuit in room, two signal end are electrically connected with ventricle electrofiltration wave circuit and ventricle electricity analog-digital converter respectively, and being used for will The analog signal of the ventricle electricity received from ventricle electrofiltration wave circuit, which is amplified and exported, gives ventricle electricity analog-digital converter;The ventricle Electric analog-digital converter, two signal end are electrically connected with the electrically amplified circuit of ventricle and central processing unit respectively, and being used for will be from ventricle The analog signal for the ventricle electricity that electrically amplified circuit receives is converted into digital signal and exports to central processing unit.
Further, the magnetic field signal processing unit includes: magnetic field analog-digital converter, external magnetic field receptor and with number Word switch electrical connection, the analog signal for being generated with fixed frequency acquisition magnetic field receptor, and number is converted by analog signal Word signal is exported to digital switch;Digital switch is electrically connected with magnetic field analog-digital converter and central processing unit, for according to default The digital signal received is converted to logical signal, and logical signal is exported to the central processing unit by fixed threshold value.
Further, the ventricular pressure aware circuit includes: ventricular pressure filter circuit, external pressure sensor and and ventricle Amplifying circuit electrical connection is pressed, is pressed for that will be filtered out and be exported from the collected ventricular pressure signal of pressure sensor to ventricle Big circuit;Ventricular pressure amplifying circuit is electrically connected with ventricular pressure filter circuit and ventricular pressure analog-digital converter, and being used for will be from ventricular pressure The signal that filter circuit receives, which amplifies and exports, gives ventricular pressure analog-digital converter;Ventricular pressure analog-digital converter, presses with ventricle Big circuit and central processing unit electrical connection, for the analog signal received from ventricular pressure amplifying circuit to be converted into digital signal And it exports to central processing unit.
Further, the magnetic field signal processing unit includes magnetic field analog-digital converter, digital switch, the magnetic field modulus Converter, external magnetic field receptor are simultaneously electrically connected with digital switch, the mould for being generated with fixed frequency acquisition magnetic field receptor Quasi- signal, and convert digital signal for analog signal and export to digital switch;The digital switch, with magnetic field analog-digital converter It is electrically connected with central processing unit, for the digital signal received being converted to logical signal, and will according to presetting threshold value Logical signal is exported to the central processing unit.
Present invention simultaneously provides a kind of sides of the double sensory perceptual systems of the ventricle of Implanted cardiac pacemaker electricity-ventricular pressure signal Method characterized by comprising
Step 1, initialization directive register instruction value are 0, and ventricle inductance is selected to know pacing mode;
The logic signal value of step 2, fixed frequency read status register, the logic signal value are 0 or 1, execute step Rapid 3;
Step 3, the logical order value for reading command register at once, if the logical order value and shape of command register at this time The logic signal value of state register is inconsistent, executes step 4;If the logical order value of command register and patrolling for status register It is consistent to collect signal value, executes step 2;
Step 4, the logical order value for updating command register execute step 5;
Step 5, the logical order for executing instruction register at once simultaneously execute step 2.
In summary illustrate, the present invention provides a kind of double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker And method.Under artificial or spontaneous high interference of electromagnetic field scene, this system magnetic field signal processing unit can be with for the invention Automatic sensing changes of magnetic field and know pacing mode by ventricle inductance-ventricular pacing mode is switched to ventricular pressure perception-ventricle Mode of fighting overcomes conventional pacemaker herein by the maintenance of ventricular pressure signal to the effectively perceive and demand pacing of heart movement The competitive cardiac rhythm being likely to occur under scene with fixed frequency ventricular pacemaking, and arrhythmia cordis is induced, irreversible damage is caused to heart The phenomenon that hurting, guarantees the stabilization of cardiac hemodynamic, to greatly improve operation safety.
Meanwhile the double sensory perceptual systems of ventricle electricity-ventricular pressure proposed by the present invention can cancel original pacemaker reed and set Meter avoids under using interference scenes such as the surgical operation of electric knife and high electromagnetic fields, and reed switch is possibly can not be just normally opened It opens or closes, cause pacemaker that cannot normally perceive ventricular electrical signal and provide pulse, what effective protection was implanted a pacemaker Patient.
It is described further below with reference to technical effect of the attached drawing to design of the invention, specific structure and generation, with It is fully understood from the purpose of the present invention, feature and effect.
Detailed description of the invention
Fig. 1 is the structural block diagram of the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker of the invention.
Fig. 2 is magnetic field signal processing unit structural block diagram of the invention.
Fig. 3 is ventricular pressure aware circuit structural block diagram of the invention.
Fig. 4 is that ventricle inductance of the invention knows circuit structure block diagram.
Fig. 5 is central processing unit functional module structure block diagram of the invention.
Fig. 6 is the flow chart of magnetic field signal processing unit of the invention.
Fig. 7 is the flow chart of perception pacing mode decision of the invention.
Drawing reference numeral explanation:
Central processing unit 1, magnetic field signal processing unit 2, ventricular pressure aware circuit 3, ventricle electricity aware circuit 4, pacemaker Microprocessor 5, pressure sensor 6, electrode terminal 7, pacing circuitry 8, magnetic field receptor 9, digital switch 10, magnetic field analog-to-digital conversion Device 11, ventricular pressure analog-digital converter 12, ventricular pressure amplifying circuit 13, ventricular pressure filter circuit 14, ventricle electricity analog-digital converter 15, Ventricle electrically amplified circuit 16, status register 18, communication module 19, command register 20, perceives ventricle electrofiltration wave circuit 17 It fights mode decision module 21.
Specific embodiment
In the description of embodiments of the present invention, it is to be understood that term " on ", "lower", "front", "rear", " left side ", The orientation of the instructions such as " right side ", " vertical ", "horizontal", "top", "bottom", "inner", "outside", " clockwise ", " counterclockwise " or position are closed System is merely for convenience of description of the present invention and simplification of the description to be based on the orientation or positional relationship shown in the drawings, rather than indicates Or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot understand For limitation of the present invention.Attached drawing is schematic diagram or concept map, relationship and each section between each section thickness and width Between proportionate relationship etc., it is not completely the same with its actual value.
Below in conjunction with attached drawing to the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker proposed by the present invention into One step is described in detail.It should be noted that attached drawing uses the form of succinct overview, it is not covered by whole needed for realizing the control method Hardware information, only to convenient, the clearly aid illustration embodiment of the present invention the purpose.
Fig. 1 shows a kind of double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker proposed by the present invention Structural block diagram.This system includes that central processing unit 1, magnetic field signal processing unit 2, ventricular pressure aware circuit 3, ventricle inductance know electricity Road 4.The external magnetic field receptor 9 of magnetic field signal processing unit 2, is converted to logical signal for artificial or spontaneous magnetic field strength It is input in central processing unit 1;The external pressure sensor 6 of ventricular pressure aware circuit 3 provides perception, the processing of ventricular pressure signal And it is transferred to central processing unit 1;The electrode terminal 7 of the external pacemaker of ventricle electricity aware circuit 4, provides the sense of ventricular electrical signal Know, handle and is transferred to central processing unit 1;The external pacemaker microprocessor 5 of central processing unit 1, and respectively and at magnetic field signal Unit 2 is managed, ventricular pressure aware circuit 3 and ventricle electricity aware circuit 4 communicate, and central processing unit 1 is the double senses of ventricle electricity-ventricular pressure Know that system control provides perception pacing mode logical order and interacts with pacemaker microprocessor 5, the pace-making extraction of microprocessor 5 refers to It enables and after perceptual signal, controls pacing circuitry 8 and electric the end extremely 7 corresponding ventricular pacemaking of progress of son;The present invention passes through central processing Device improves implantable cardiac and rises to a variety of different types of information, such as the integrated treatment of ventricle electricity, ventricular pressure and magnetic field information Device fight to the accuracy of heart working state description, enhances pacemaker reliability and safety.
The connection relationship and effect of each component of the invention described further below.
As shown in Fig. 2, magnetic field signal processing unit 2 includes digital switch 10 and magnetic field analog-digital converter 11;Wherein magnetic field Analog-digital converter 11 is connected with magnetic field receptor 9 and digital switch 10 respectively;Digital switch 10 respectively with magnetic field analog-digital converter 11 are connected with central processing unit 1.Magnetic field analog-digital converter 11 is with the simulation letter of the generation of fixed frequency acquisition magnetic field receptor 9 Number, and convert digital signal for analog signal and export to digital switch 10;Digital switch 10 will connect according to presetting threshold value The digital signal received is converted to logical signal, and logical signal is exported to central processing unit 1.
In the present embodiment, if pacemaker carrier is in artificial or spontaneous interference of electromagnetic field scene, Artificially apply highfield outside liptinite when such as surgical operation, magnetic field receptor 9 extracts Magnetic Field, and output is given fixed frequency and adopted In the magnetic field analog-to-digital conversion device 11 of sample, as shown in fig. 6, to judge whether the magnetic field sampled value exceeds pre- for magnetic field signal processing unit 2 The threshold value first set, if beyond the threshold value that set logical signal as 1, if without departing from the threshold value logical signal set as 0, general The logical signal is sent in the status register 18 of central processing unit 1.
As shown in figure 3, ventricular pressure aware circuit 3 includes ventricular pressure filter circuit 14, ventricular pressure amplifying circuit 13 and ventricle Pressing mold number converter 12;Wherein ventricular pressure filter circuit 14 respectively with for incuding ventricle pressure sensor 6 and ventricle press Big circuit 13 is connected;Ventricular pressure analog-digital converter 12 is connected with central processing unit 1 and ventricular pressure amplifying circuit 13 respectively.Feeling of stress The ventricular pressure signal that receiver 6 is acquired with upper frequency is after ventricular pressure filter circuit 14, filtering interference signals, exports to ventricle Press amplifying circuit 13;Amplification by ventricular pressure amplifying circuit 13 to small signal will be put using ventricular pressure analog-digital converter 12 Ventricular pressure analog signal after big is converted into digital signal, exports to central processing unit 1.
As shown in figure 4, ventricle electricity aware circuit 4 includes ventricle electrofiltration wave circuit 17, the electrically amplified circuit 16 of ventricle and ventricle Electric analog-digital converter 15;Its centre chamber's electrofiltration wave circuit 17 respectively with the electrode terminal of pacemaker 7 and the electrically amplified circuit 16 of ventricle It is connected;Ventricle electricity analog-digital converter 15 is connected with central processing unit 1 and the electrically amplified circuit 16 of ventricle respectively.Pacemaker electrode terminal 7 ventricular electrical signals acquired with upper frequency after ventricle electrofiltration wave circuit 17, put to ventricle electricity by filtering interference signals, output Big circuit 16;Amplification by the electrically amplified circuit 16 of ventricle to small signal, after amplifying using ventricle electricity analog-digital converter 15 Ventricle electric analoging signal be converted into digital signal, export to central processing unit 1.
As shown in figure 5, the central processing unit is by perception pacing mode decision module 21, communication module 19, order register Device 20, status register 18 are constituted.
Particularly, status register 18 is electrically connected with magnetic field signal processing unit 2 and perception pacing mode decision module 21, For recording the logical message of the magnetic field signal processing unit 2 and being converted into logic signal value.
Command register 20, one end are bi-directionally connected with perception pacing mode decision module 21, for storing from perception The logical order value of mode decision module 21 of fighting sending is simultaneously exported to communication module 19, while by logical order value with fixed frequency Feed back to perception pacing mode decision module 21.
Perceive pacing mode decision module 21, the output end of one signal input part connection status register 18, remaining part Sub-signal end is separately connected command register 20, ventricular pressure aware circuit 4, ventricle electricity aware circuit 3 and communication module 19, receives The logical order value that the logical message value and command register 20 that status register 18 issues are fed back with fixed frequency, if instruction is posted The logical order value of storage 20 is consistent with the logic signal value of status register 18, then keeps the logical order of command register 20 Be worth it is constant, if the logical order value of command register 20 and the logic signal value of status register 18 are inconsistent, more new command The logical order value of register 20, the updated logical order value of command register 20 and the aware circuit signal selected will be by Communication module 19 is read.
Particularly, setting is known there are two types of pacing algorithm, respectively ventricle inductance is perceived in perception pacing mode decision module Pacing algorithm VVEI and ventricular pressure perceive pacing algorithm VVPI, in the present embodiment, two kinds of perception pacing algorithms and central processing unit 1 logical order value corresponding relationship is as follows:
Certainly, central processing unit logical order value 0 can also be defined as interrupting ventricle electricity aware circuit letter as needed Number, corresponding perception pacing mode program unit is VVPI, remaining corresponding relationship sequence adjust, and details are not described herein again.
Communication module 19, two signal end is corresponding to determine with 20 output end of command register and perception pacing mode The electrical connection of 21 output end of cover half block, for obtaining logical order value and corresponding perceptual signal information, the other end is for two-way Pacemaker microprocessor 5 is connected, for realizing information such as data, orders between central processing unit 1 and pacemaker microprocessor 5 Communication.Communication module 19 uses Universal Serial Interface SPI protocol, master-slave mode, and central processing unit 1 is host, and pacemaker is micro- Processor 5 is slave.
It is same by pacemaker microprocessor 5 after pacing 5 extraction logic instruction value of microprocessor and corresponding aware circuit signal Step executes programmed instructions VVEI, control pacing circuitry 8 and electric end extremely son 7 carry out corresponding ventricular pacemaking.
In addition, the double sensory perceptual systems of ventricle electricity-ventricular pressure based on above-mentioned Implanted cardiac pacemaker, the present invention also provides A kind of method of the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker, the specific steps are as follows:
Step 1, as shown in fig. 7, in the present embodiment, under initial situation, the command register 20 of central processing unit 1 is patrolled Collecting instruction initial value is 0, and perception pacing mode decision module 21 will interrupt 3 signal of ventricular pressure aware circuit and execute VVEI journey Sequence, and the initial order is interacted by communication module 19 to pacemaker microprocessor 5 with the signal of ventricle electricity aware circuit 4; After pacemaker microprocessor 5 extracts instruction and ventricular electrical signal, pacemaker microprocessor 5 is synchronous to execute programmed instructions VVEI, Control pacing circuitry 8 and electrode terminal 7 carry out corresponding ventricular pacemaking.
Step 2, as shown in fig. 7, the perception pacing mode decision module 21 of central processing unit 1 with fixed frequency reading state Logic signal value in register 18.
Step 3, as shown in fig. 7, if the logic signal value of status register 18 be 0, central processing unit 1 continue read instruction The information of register 20 keeps current perception pacing mode order constant if the logical order value of command register 20 is 0, Execute step 2;If the logical order value of command register 20 is 1, switches current perception pacing mode, execute step 1.
Step 4: if the logical signal of status register 18 is 1, being posted as shown in fig. 7, central processing unit 1 continues to read to instruct The information of storage 20: it if the logical order value of command register 20 is 1, keeps current perception pacing mode order constant, holds Row step 2;If the logical order value of command register 20 is 0;The logical order value for then updating command register is 1, and switching is worked as Preceding perception pacing mode, and execute step 5.
Step 5: as shown in fig. 7, in the command register 20 that status register signal value is 1 and central processing unit 1 In the case that logical order value is 0, the logical order value for updating command register is 1 and perception pacing mode decision module 21 will 4 signal of ventricle electricity aware circuit is interrupted, and the update instruction value is handed over 3 signal of ventricular pressure aware circuit by communication module 19 Mutually give pacemaker microprocessor 5;After pacing 5 extraction logic instruction value of microprocessor and ventricular pressure signal, pass through the micro- place of pacemaker Manage the synchronous execution programmed instructions VV of device 5PI, control pacing circuitry 8 and electric end extremely son 7 carry out corresponding ventricular pacemaking, and execute Step 2.
By above description, the present invention provides a kind of double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker And method.Under artificial or spontaneous high interference of electromagnetic field scene, this system magnetic field signal processing unit can be with for the invention Automatic sensing changes of magnetic field and know pacing mode by ventricle inductance-ventricular pacing mode is switched to ventricular pressure perception-ventricle Mode of fighting overcomes conventional pacemaker herein by the maintenance of ventricular pressure signal to the effectively perceive and demand pacing of heart movement The competitive cardiac rhythm being likely to occur under scene with fixed frequency ventricular pacemaking, and arrhythmia cordis is induced, irreversible damage is caused to heart The phenomenon that hurting, ensure that the stabilization of cardiac hemodynamic, to greatly improve operation safety.
Meanwhile the double sensory perceptual systems of ventricle electricity-ventricular pressure proposed by the present invention can cancel original pacemaker reed and set Meter avoids under the surgical operation and high interference of electromagnetic field scene using electric knife, and reed switch is possibly can not be normally-open Or close, cause pacemaker that cannot normally perceive ventricular electrical signal and provides pulse, the trouble that effective protection is implanted a pacemaker Person.
The preferred embodiment of the present invention has been described in detail above.It should be appreciated that those skilled in the art without It needs creative work according to the present invention can conceive and makes many modifications and variations.Therefore, all technologies in the art Personnel are available by logical analysis, reasoning, or a limited experiment on the basis of existing technology under this invention's idea Technical solution, all should be within the scope of protection determined by the claims.

Claims (10)

1. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker characterized by comprising
Magnetic field signal processing unit is used for external magnetic field receptor, artificial or spontaneous magnetic field strength is converted to logic Signal;
Ventricle electricity aware circuit obtains the signal of ventricle electricity and carries out signal processing for the electrode terminal of external pacemaker;
Ventricular pressure aware circuit is used for external pressure sensor, obtains the signal of ventricular pressure and carry out signal processing;
Central processing unit, for connecting pacemaker microprocessor, remaining corresponding signal end is separately connected described one signal end Magnetic field signal processing unit, ventricular pressure aware circuit, ventricle electricity aware circuit receive the logic letter of magnetic field signal processing unit Number, the ventricular pressure signal that provides of the ventricular electrical signal that provides of ventricle electricity aware circuit and ventricular pressure aware circuit, and and pacemaker Microprocessor interaction, being responsible for switching perception pacing mode is that ventricle inductance knows that pacing mode or ventricular pressure perceive pacing mode.
2. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as described in claim 1, which is characterized in that The central processing unit includes perception pacing mode decision module, status register, command register, communication module;
It is defeated to receive and store magnetic field signal processing unit for connecting the magnetic field signal processing unit for the status register Logical signal out is converted into the logic signal value of digital signal by analog signal;
The corresponding signal end of described instruction register, one end and perception pacing mode decision module is bi-directionally connected, for storing It from the logical order value for perceiving the sending of pacing mode decision module and exports to communication module, while by logical order value with fixation Frequency feedback gives perception pacing mode decision module;
The perception pacing mode decision module, one signal input part connect the output end of the status register, remaining phase Induction signal end is connected respectively ventricular pressure aware circuit, ventricle electricity aware circuit;For to receiving from command register It is corresponding that logical order value and the logic signal value transmitted from status register carry out unification, and by the logical order value after correspondence It exports together with corresponding ventricular electrical signal or ventricular pressure signal to communication module;
The communication module, two signal end respectively with it is described perception pacing mode decision module output end, order register The output end of device is correspondingly connected with, for obtaining logical order value and corresponding ventricular electrical signal or ventricular pressure signal, another letter The corresponding signal end for being bi-directionally connected the pacemaker microprocessor number is held, for realizing central processing unit and the micro- place of pacemaker Manage the communication between device.
3. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as claimed in claim 2, which is characterized in that When the magnetic field strength is greater than the threshold value of setting, the logic signal value of status register is 1;Magnetic field strength is less than the threshold of setting Value, the logic signal value of status register are 0.
4. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as claimed in claim 2, which is characterized in that The logical order value is corresponding with the unification of the logic signal value, if referring to the logical order value and state of command register The logic signal value of register is consistent, then keeps the logical order value of command register constant, if the logic of command register refers to It enables the logic signal value of value and status register inconsistent, then updates the logical order value of command register.
5. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as claimed in claim 2, which is characterized in that When the logical order value of described instruction register is 1, the signal of ventricle electricity aware circuit is interrupted, enables ventricular pressure aware circuit Signal;When instruction value is 0, the signal of ventricular pressure aware circuit is interrupted, enables the signal of ventricle electricity aware circuit.
6. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as claimed in claim 2, which is characterized in that The communication module uses Universal Serial Interface SPI protocol, and master-slave mode, central processing unit is host, pacemaker microprocessor For slave.
7. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as described in claim 1, which is characterized in that The ventricle electricity aware circuit includes ventricle electrofiltration wave circuit, the electrically amplified circuit of ventricle, ventricle electricity analog-digital converter;
The ventricle electrofiltration wave circuit, the electrode terminal of external pacemaker are simultaneously electrically connected with the electrically amplified circuit of ventricle, for will be from Output gives ventricle electrically amplified circuit after the analog signal of the collected ventricle electricity of electrode terminal carries out filtering clutter;
The electrically amplified circuit of ventricle, two signal end are electrically connected with ventricle electrofiltration wave circuit and ventricle electricity analog-digital converter respectively It connects, the analog signal of the ventricle electricity for will receive from ventricle electrofiltration wave circuit, which is amplified and exported, gives ventricle electricity analog-to-digital conversion Device;
The ventricle electricity analog-digital converter, two signal end are electrically connected with the electrically amplified circuit of ventricle and central processing unit respectively, The analog signal of ventricle electricity for will receive from the electrically amplified circuit of ventricle is converted into digital signal and exports to central processing Device.
8. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as described in claim 1, which is characterized in that The ventricular pressure aware circuit includes ventricular pressure filter circuit, ventricular pressure amplifying circuit, ventricular pressure analog-digital converter;
The ventricular pressure filter circuit, external pressure sensor are simultaneously electrically connected with ventricular pressure amplifying circuit, for that will pass from pressure The analog signal of the collected ventricular pressure of sensor, which is filtered out and exported, gives ventricular pressure amplifying circuit;
The ventricular pressure amplifying circuit, is electrically connected with ventricular pressure filter circuit and ventricular pressure analog-digital converter, and being used for will be from ventricle The analog signal for the ventricular pressure that filters pressing wave circuit receives, which is amplified and exported, gives ventricular pressure analog-digital converter;
The ventricular pressure analog-digital converter, is electrically connected with ventricular pressure amplifying circuit and central processing unit, for that will press from ventricle The analog signal for the ventricular pressure that big circuit receives is converted into digital signal and exports to central processing unit.
9. the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker as described in claim 1, which is characterized in that The magnetic field signal processing unit includes magnetic field analog-digital converter, digital switch;
The magnetic field analog-digital converter, external magnetic field receptor are simultaneously electrically connected with digital switch, for acquiring magnetic with fixed frequency The analog signal that field receptor generates, and convert digital signal for analog signal and export to digital switch;
The digital switch is electrically connected with magnetic field analog-digital converter and central processing unit, for will connect according to presetting threshold value The digital signal being subject to is converted to logical signal, and logical signal is exported to the central processing unit.
10. the method for the double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker characterized by comprising
Step 1, initialization directive register instruction value are 0, and ventricle inductance is selected to know pacing mode;
The logic signal value of step 2, fixed frequency read status register, the logic signal value are 0 or 1, are executed
Step 3;
Step 3, the logical order value for reading command register at once, if the logical order value of command register is posted with state at this time The logic signal value of storage is inconsistent, executes step 4;If the logical order value of command register and the logic of status register are believed Number value is consistent, executes step 2;
Step 4, the logical order value for updating command register execute step 5;
Step 5, the logical order for executing instruction register at once simultaneously execute step 2.
CN201811520752.5A 2018-12-12 2018-12-12 The double sensory perceptual systems of ventricle electricity-ventricular pressure of Implanted cardiac pacemaker and method Pending CN109331338A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5978710A (en) * 1998-01-23 1999-11-02 Sulzer Intermedics Inc. Implantable cardiac stimulator with safe noise mode
US20120277818A1 (en) * 2011-04-29 2012-11-01 Medtronic, Inc. Multiphasic pacing in the presence of electromagnetic interference
CN103068302A (en) * 2010-05-13 2013-04-24 合理医疗创新有限公司 Method and system for using distributed electromagnetic (EM) tissue(s) monitoring
US20140100624A1 (en) * 2012-10-09 2014-04-10 Medtronic, Inc. Cardiac pacing during medical procedures
US20160067490A1 (en) * 2014-09-08 2016-03-10 Medtronic, Inc. Dual chamber timing for leadless pacemakers using infrequent atrial signals and ventricular contractions
CN106029165A (en) * 2013-12-19 2016-10-12 拜克比特医疗公司 Methods and systems for controlling blood pressure by controlling atrial pressure
CN106474625A (en) * 2016-10-31 2017-03-08 乐普医学电子仪器股份有限公司 The method eliminating the High-frequency Interference of phase ventricular between Implanted cardiac pacemaker AV

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5978710A (en) * 1998-01-23 1999-11-02 Sulzer Intermedics Inc. Implantable cardiac stimulator with safe noise mode
CN103068302A (en) * 2010-05-13 2013-04-24 合理医疗创新有限公司 Method and system for using distributed electromagnetic (EM) tissue(s) monitoring
US20120277818A1 (en) * 2011-04-29 2012-11-01 Medtronic, Inc. Multiphasic pacing in the presence of electromagnetic interference
US20140100624A1 (en) * 2012-10-09 2014-04-10 Medtronic, Inc. Cardiac pacing during medical procedures
CN106029165A (en) * 2013-12-19 2016-10-12 拜克比特医疗公司 Methods and systems for controlling blood pressure by controlling atrial pressure
US20160067490A1 (en) * 2014-09-08 2016-03-10 Medtronic, Inc. Dual chamber timing for leadless pacemakers using infrequent atrial signals and ventricular contractions
CN106474625A (en) * 2016-10-31 2017-03-08 乐普医学电子仪器股份有限公司 The method eliminating the High-frequency Interference of phase ventricular between Implanted cardiac pacemaker AV

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