CN109330748A - A kind of ankle prosthesis shin bone sidepiece part - Google Patents

A kind of ankle prosthesis shin bone sidepiece part Download PDF

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Publication number
CN109330748A
CN109330748A CN201811391123.7A CN201811391123A CN109330748A CN 109330748 A CN109330748 A CN 109330748A CN 201811391123 A CN201811391123 A CN 201811391123A CN 109330748 A CN109330748 A CN 109330748A
Authority
CN
China
Prior art keywords
side component
fixed
tibial side
shin bone
bearing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811391123.7A
Other languages
Chinese (zh)
Inventor
朱敏
唐康来
卢衍锦
林锦新
唐红
张臣科
谢美明
郭宇鹏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanfang Hospital
First Affiliated Hospital of PLA Military Medical University
Original Assignee
First Affiliated Hospital of PLA Military Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of PLA Military Medical University filed Critical First Affiliated Hospital of PLA Military Medical University
Priority to CN201811391123.7A priority Critical patent/CN109330748A/en
Publication of CN109330748A publication Critical patent/CN109330748A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4202Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for ankles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30721Accessories
    • A61F2/30728Collars; Bone edge protectors
    • A61F2002/30729Separate collars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30985Designing or manufacturing processes using three dimensional printing [3DP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/42Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes
    • A61F2/4202Joints for wrists or ankles; for hands, e.g. fingers; for feet, e.g. toes for ankles
    • A61F2002/4205Tibial components

Abstract

The invention discloses a kind of ankle prosthesis shin bone sidepiece parts, including titanium alloy tibial side component and fixed-bearing, the top of titanium alloy tibial side component is equipped with upper bearing surface, the quadrangle of upper bearing surface is fixed with the pin of four protrusions respectively, screw hole is equipped in the middle part of titanium alloy tibial side component, what four pins and tabernacle closed that screw is fixed as distal tibial on titanium alloy tibial side component after bearing surface and osteotomy is connected and fixed offer incipient stability, the surface of upper bearing surface is cancellous bone porous structure, with biological function, it provides stable again, it is grown convenient for prosthese and osteotomy surface rapid fusion;Fixed-bearing top is equipped with upper joint face, and the lower chimeric surface of upper joint face and titanium alloy tibial side component is connected and fixed, and fixed-bearing bottom end is equipped with lower slider face, and lower slider face matches with tibial prosthesis face;Upper bearing surface, lower chimeric surface, upper joint face, lower slider face are arc, and prosthese is made to be more in line with the real ankle joint structure of human body.

Description

A kind of ankle prosthesis shin bone sidepiece part
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of ankle prosthesis shin bone sidepiece parts.
Background technique
Artificial joint prosthesis is mainly used in the pain of ankle-joint caused by various wounds, autoimmune disease, degenerative disease Bitterly, the patient that deformity, function are lost.For ankle-joint, currently used ankle fusion can be such that patient loses almost The motor function of whole ankle-joints, ankle-joint replace the motor function that can retain most of ankle-joint, and thoroughly solve patient's Pain and lopsided problem.Home and abroad patent consulting is not the results show that the design of existing full ankle prosthesis is complete bionical symbol The real ankle-joint anatomical structure of human body is closed, biomethanics also changes, and does not meet the characteristics of motion and feature under physiological conditions. Therefore, prosthese revision rate, prosthetic loosening rate, unstability are high.More than half since the first generation manually full ankle-joint application Century, the stability and persistence of joint prosthesis are always to limit the main factor of its development.And patient is for quality of life It is required that increasingly increasing, so requiring also to increase therewith for ankle joint function.But current ankle prosthesis cannot still provide good In the case where stability well, persistence and good function, the design and invention for carrying out novel artificial ankle prosthesis can be mentioned For patient's preferably therapeutic modality, mitigate patient suffering, lowers patient's deformity, disabled probability, greatly improve the life of patient Quality.
Application No. is the Chinese patents of CN201710754997.3 to disclose a kind of anatomical form fixed-bearing ankle-joint before this Prosthese, there are full ankle prosthesis revision rate height, loosening rate are high and stable for disclosed anatomical form fixed-bearing ankle prosthesis The low defect of property, now improves its tibial side component, provides a kind of new ankle prosthesis shin bone sidepiece part.
Shin bone or other bones integrally remove displacement class operation the fusion growth of prosthese and other positions is generally used it is general Logical porous structure can satisfy requirement, but for the operation of femoral surface displacement etc, for melting for postoperative prosthese and shin bone The long requirement of symphysis is higher, higher to the requirement of femoral surface replacement prosthesis, and the femoral surface replacement prosthesis for needing one kind novel can Preferably and shin bone fusion growth is to mitigate patient suffering, lowers patient's deformity, disabled probability, greatly improves the life of patient Quality.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of ankle prosthesis shin bone sidepiece part, to solve in the prior art ?.
The present invention solves above-mentioned technical problem by following technological means:
A kind of ankle prosthesis shin bone sidepiece part, including tibial side component and fixed-bearing, the shape of the tibial side component Shape and individual patients are matched by damage femoral surface anatomical shape, and the top of the tibial side component is equipped with upper bearing surface, institute of institute The bottom for stating tibial side component is provided with lower chimeric surface, and the pin of four protrusions is fixed on the quadrangle of the upper bearing surface It is fixedly connected with the distal tibial after osteotomy, tabernacle is provided in the middle part of the tibial side component and closes screw, for reinforcing tibial side Component is fixedly connected with shin bone, and fixed-bearing is equipped on the lower chimeric surface, and the top of the fixed-bearing is equipped with upper Joint face, the upper joint face fit with lower chimeric surface, and the bottom of the fixed-bearing is provided with lower slider face, the upper branch The surface of bearing surface is porous structure, has biological function, the layout and shape of the porous structure on the upper bearing surface and trouble Person is accordingly matched by the trabecular bone structure of damage femoral surface concave and convex part.
The present invention carries out finite element analysis by the geometry to prosthese and experiment of machanics demonstrates the initial steady of prosthese Qualitative differences, and carried out in vitro by the exemplar to 3D printing individuation shin bone trabecular bone structure and the exemplar of common porous structure With intracorporal biocompatibility experiment, it was demonstrated that the stability again of prosthese.
Experiment in vitro of the invention be using adherency of the mescenchymal stem cell on the exemplar of different porous structures, proliferation, The biological behaviours such as differentiation, apoptosis, and observe, record the expression of its skeletonization coherent signal, to judge different porous structures Bio-compatible implementations;Experiment in vivo be by manufacture goat shin bone neuropathy model, take the prosthese of different porous structures into Line replacement observes the difference of Bone Ingrowth by Microct inspection and hard tissue slicing, to judge the biology of different porous structures Compatible implementations.The results show that the shin bone of the porous structure of individuation shin bone trabecular bone structure-prosthese interface Bone Ingrowth has Advantage.
Further, the upper bearing surface, lower chimeric surface, upper joint face, lower slider face are arc, meet model of human ankle Structure.
Further, it is hollow structure that the tabernacle, which closes screw, and is matched with the screw hole in tibial side component, the tabernacle Screw is closed to be mounted on inside screw hole.
Further, the tibial side component is made of titanium alloy.
Beneficial effects of the present invention:
The present invention can be improved the stability of prosthese, realizes the biomechanical function for quickly repairing, rebuilding ankle-joint, mitigates Patient suffering reduces patient's deformity, disabled probability.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of ankle prosthesis shin bone sidepiece part of the present invention;
Fig. 2 is a kind of structural schematic diagram of the tibial side component of ankle prosthesis shin bone sidepiece part of the present invention;
Fig. 3 is a kind of structural representation of the lower chimeric surface of the tibial side component of ankle prosthesis shin bone sidepiece part of the present invention Figure;
Fig. 4 is a kind of top view of the tibial side component of ankle prosthesis shin bone sidepiece part of the present invention;
Fig. 5 is a kind of structural schematic diagram of the fixed-bearing of ankle prosthesis shin bone sidepiece part of the present invention;
Fig. 6 is the structural schematic diagram that a kind of tabernacle of ankle prosthesis shin bone sidepiece part of the present invention closes screw;
Fig. 7 is the osteoblast number statistical chart of experiment in vitro of the invention;
Fig. 8 is alkaline phosphatase (ALP) content statistical chart of experiment in vitro of the invention;
Wherein, tibial side component 1, upper bearing surface 11, lower chimeric surface 12, screw hole 13, porous structure 14, fixed-bearing 2, Upper joint face 21, lower slider face 22, pin 3, tabernacle close screw 4, entity structure group A, bone trabecula porous structure group B, common porous Structure group C.
Specific embodiment
Below with reference to the drawings and specific embodiments, the present invention is described in detail:
As shown in figs 1 to 6, a kind of ankle prosthesis shin bone sidepiece part, including tibial side component 1 and fixed-bearing 2, institute The shape and individual patients for stating tibial side component 1 are matched by damage femoral surface anatomical shape, the top of the tibial side component 1 Equipped with upper bearing surface 11, the bottom of the tibial side component 1 be provided with lower chimeric surface 12, on the quadrangle of the upper bearing surface 11 The pin 3 for being fixed with four protrusions is fixedly connected with the distal tibial after osteotomy, the middle part setting of the tibial side component 1 There is tabernacle to close screw 4, for reinforcing being fixedly connected for tibial side component 1 and shin bone, fixed lining is installed on the lower chimeric surface 12 Pad 2, the upper joint face 21 that the top of the fixed-bearing 2 is equipped with, the upper joint face 21 fits with lower chimeric surface 12, described The bottom of fixed-bearing 2 is provided with lower slider face 22, and the surface of the upper bearing surface 11 is porous structure 14, has biology function Can, the layout and shape of the porous structure 14 on the upper bearing surface 11 and patient are by the bone trabecula of damage femoral surface concave and convex part Structure accordingly matches, and grows convenient for tibial side component 1 and osteotomy surface rapid fusion.
Upper bearing surface 11, lower chimeric surface 12, upper joint face 21, lower slider face 22 are arc, meet model of human ankle knot Structure.
Finite element analysis is carried out by the geometry to prosthese in the present embodiment and experiment of machanics demonstrates the first of prosthese Beginning stability difference, and carried out by the exemplar to 3D printing individuation shin bone trabecular bone structure and the exemplar of common porous structure The biocompatibility experiment of in vitro and in vivo, it was demonstrated that the stability again of prosthese.
Experiment in vitro is adherency, the increasing using mescenchymal stem cell on the exemplar of different porous structures in the present embodiment It grows, break up, the biological behaviours such as apoptosis, and observing, record the expression of its skeletonization coherent signal, to judge different porous structures Bio-compatible implementations;Experiment in vivo is the shin bone neuropathy model by manufacturing goat, takes the prosthese of different porous structures It is replaced, the difference of Bone Ingrowth is observed by Microct inspection and hard tissue slicing, to judge the life of different porous structures The compatible implementations of object.The results show that the shin bone of the porous structure of individuation shin bone trabecular bone structure-prosthese interface Bone Ingrowth has It is advantageous.
The stability again of bone and prosthese relies primarily on growing into for bone, and prosthese and bone fusion are integrated, and osteoblast is into The main cell of bone, alkaline phosphatase (ALP) etc. facilitate the relevant factor pair skeletonization adjustment effect of bone;Osteoblast is more, promotees Factor content into skeletonization is higher, and skeletonization is more obvious.
It is set in vitro experiment referring to Fig. 7 to measure the prosthese of different porous structures and the bio-compatible implementations of shin bone Determine three kinds of prostheses and done comparative experiments, is respectively as follows: entity structure group A, bone trabecula porous structure group B, common porous structure group C, Prosthese in entity structure group A does not open up porous structure, the vacation in bone trabecula porous structure group B on the surface of upper bearing surface 11 Body offers the porous structure to match with shin bone trabecular bone structure, common porous structure group C on the surface of upper bearing surface 11 In prosthese the porous structure of general structure is offered on the surface of upper bearing surface 11, in figure 5 it can be seen that bone trabecula porous structure Osteoclast number in group B is obviously than other more than two groups.
It is the alkaline phosphatase of the experiment in vitro of personalized femoral surface replacement prosthesis in the present embodiment referring to Fig. 8, Fig. 8 (ALP) content statistical chart, in figure 5 it can be seen that the skeletonization correlation factor ALP content in bone trabecula porous structure group B is obviously than other two Group is high.
Therefore, referring to Fig. 7 and Fig. 8 it can be proved that shin bone-prosthese circle of the porous structure of individuation shin bone trabecular bone structure The Bone Ingrowth in face has advantage, and the stability again of bone and prosthese is more preferable.
The above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to preferred embodiment to this hair It is bright to be described in detail, those skilled in the art should understand that, it can modify to technical solution of the present invention Or equivalent replacement should all cover without departing from the objective and range of technical solution of the present invention in claim of the invention In range.Technology not described in detail in the present invention, shape, construction portion are well-known technique.

Claims (4)

1. a kind of ankle prosthesis shin bone sidepiece part, it is characterised in that: described including tibial side component (1) and fixed-bearing (2) The shape and individual patients of tibial side component (1) are matched by damage femoral surface anatomical shape, the top of the tibial side component (1) Portion is equipped with upper bearing surface (11), the bottom of the tibial side component (1) be provided with lower chimeric surface (12), the upper bearing surface (11) pin (3) that four protrusions are fixed on quadrangle is fixedly connected with the distal tibial after osteotomy, the tibial side It is provided with tabernacle in the middle part of component (1) and closes screw (4), it is embedding under described for reinforcing being fixedly connected for tibial side component (1) and shin bone It is equipped on conjunction face (12) fixed-bearing (2), the upper joint face (21) that the top of the fixed-bearing (2) is equipped with, the upper company Junction (21) fits with lower chimeric surface (12), and the bottom of the fixed-bearing (2) is provided with lower slider face (22), the upper branch The surface of bearing surface (11) is porous structure (14), has biological function, the porous structure (14) on the upper bearing surface (11) Layout and shape and patient matched by the trabecular bone structure of damage femoral surface concave and convex part is corresponding.
2. a kind of ankle prosthesis shin bone sidepiece part according to claim 1, it is characterised in that: the upper bearing surface (11), lower chimeric surface (12), upper joint face (21), lower slider face (22) are arc, meet model of human ankle structure.
3. a kind of ankle prosthesis shin bone sidepiece part according to claim 2, it is characterised in that: the tabernacle closes screw (4) For hollow structure, and match with the screw hole (13) in the tibial side component (1), the tabernacle closes screw (4) and is mounted on Screw hole (13) is internal.
4. a kind of ankle prosthesis shin bone sidepiece part according to claim 1, it is characterised in that: the tibial side component (1) it is made of titanium alloy.
CN201811391123.7A 2018-11-20 2018-11-20 A kind of ankle prosthesis shin bone sidepiece part Pending CN109330748A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111920551A (en) * 2020-07-28 2020-11-13 北京市春立正达医疗器械股份有限公司 Primary total ankle joint prosthesis
WO2022088702A1 (en) * 2020-10-30 2022-05-05 嘉思特华剑医疗器材(天津)有限公司 Oxide layer-containing zirconium-niobium alloy ankle joint prosthetic system and manufacturing method

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* Cited by examiner, † Cited by third party
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CN105997307A (en) * 2016-05-10 2016-10-12 上海交通大学医学院附属瑞金医院 3D-printing-based restoration rebuilding method of large-range osteochondral lesions of talus
CN106473841A (en) * 2015-08-25 2017-03-08 瑞特医疗技术公司 Module astragalus fixing means and system
CN107374788A (en) * 2017-08-29 2017-11-24 中国人民解放军第三军医大学 A kind of anatomical form fixed-bearing ankle prosthesis
CN108289733A (en) * 2015-10-05 2018-07-17 孚美公司 Medical implant and fixed system for medical implant
CN108524063A (en) * 2018-04-25 2018-09-14 南方医科大学第三附属医院(广东省骨科研究院) A kind of 3D printing personalization astragalus surface replacement prosthesis
WO2018203991A1 (en) * 2017-05-04 2018-11-08 Wright Medical Technology, Inc. Bone implants with struts
CN209316157U (en) * 2018-11-20 2019-08-30 中国人民解放军陆军军医大学第一附属医院 A kind of ankle prosthesis shin bone sidepiece part

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106473841A (en) * 2015-08-25 2017-03-08 瑞特医疗技术公司 Module astragalus fixing means and system
CN108289733A (en) * 2015-10-05 2018-07-17 孚美公司 Medical implant and fixed system for medical implant
CN105997307A (en) * 2016-05-10 2016-10-12 上海交通大学医学院附属瑞金医院 3D-printing-based restoration rebuilding method of large-range osteochondral lesions of talus
WO2018203991A1 (en) * 2017-05-04 2018-11-08 Wright Medical Technology, Inc. Bone implants with struts
CN107374788A (en) * 2017-08-29 2017-11-24 中国人民解放军第三军医大学 A kind of anatomical form fixed-bearing ankle prosthesis
CN108524063A (en) * 2018-04-25 2018-09-14 南方医科大学第三附属医院(广东省骨科研究院) A kind of 3D printing personalization astragalus surface replacement prosthesis
CN209316157U (en) * 2018-11-20 2019-08-30 中国人民解放军陆军军医大学第一附属医院 A kind of ankle prosthesis shin bone sidepiece part

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111920551A (en) * 2020-07-28 2020-11-13 北京市春立正达医疗器械股份有限公司 Primary total ankle joint prosthesis
WO2022088702A1 (en) * 2020-10-30 2022-05-05 嘉思特华剑医疗器材(天津)有限公司 Oxide layer-containing zirconium-niobium alloy ankle joint prosthetic system and manufacturing method

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Application publication date: 20190215

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