CN109316523A - A kind of medicinal material Dan semen armeniacae amarae processing procedure - Google Patents

A kind of medicinal material Dan semen armeniacae amarae processing procedure Download PDF

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Publication number
CN109316523A
CN109316523A CN201811161113.4A CN201811161113A CN109316523A CN 109316523 A CN109316523 A CN 109316523A CN 201811161113 A CN201811161113 A CN 201811161113A CN 109316523 A CN109316523 A CN 109316523A
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CN
China
Prior art keywords
semen armeniacae
armeniacae amarae
dan
medicinal material
processing procedure
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Pending
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CN201811161113.4A
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Chinese (zh)
Inventor
邱志江
蔡森贤
郑媛元
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Kangmei Pharmaceutical Co Ltd
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Kangmei Pharmaceutical Co Ltd
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Priority to CN201811161113.4A priority Critical patent/CN109316523A/en
Publication of CN109316523A publication Critical patent/CN109316523A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of medicinal material Dan semen armeniacae amarae processing procedures, comprising the following steps: 1) semen armeniacae amarae is put into boiling water Dan 5-5.5min, it is disposable to take out;2) using carefully choosing peeling after cold water shower 15-18s;3) paving disk is dried, and shower is less than 2h to dry time interval is started.The semen armeniacae amarae medicine materical crude slice that this method processes amarogentin content with higher, and in batch, stable content, individual deviation are small.In concocting process, water consumption is few, peeling is convenient, reduces energy consumption.

Description

A kind of medicinal material Dan semen armeniacae amarae processing procedure
Technical field
The present invention relates to processing technique of Chinese herbs field more particularly to a kind of medicinal material Dan semen armeniacae amarae processing procedures.
Background technique
Semen armeniacae amarae is rosaceous plant ansu apricot Prunus armeniaca L.var.ansu Maxim., Siberia apricot Prunus sibirica L., prunus mandshuricaKoehne Prunus mandshurica (Maxim.) Koehne or apricot Prunus armeniaca L. dry mature seed.Summer harvests ripening fruits, removes pulp and nucleocapsid, takes out seed, dries.
It is required according to Chinese Pharmacopoeia, Dan semen armeniacae amarae concocting method are as follows: take to stir a moment, Dan in processed product investment boiling water To kind of skin by shrinkage to unfold, easily rub with the hands go when, pull out, be put into cold water, remove kind of a skin, dry.
Medicine materical crude slice is described as in flat heart, long 1~1.9cm, wide 0.8~1.5cm, 0.5~0.8cm of thickness.Surface yellowish-brown is extremely Dark-brown, one end point, another end blunt circle, plump, left-right asymmetry, there is short-term shape hilum in tip side, has upwards at nose circle chalaza Most dark-brown veins.Kind thin skin, cotyledon 2, milky are High oleic.Gas is micro-, bitter.
Preparation process technique general at present is as follows:
1) semen armeniacae amarae 50kg is put into after water boiling, pulls that (take the dish out of the pot time 1- after Dan 3-4min out several times with strainer 1.5min), circulating water takes out after impregnating cooling 1.5-2min, and draining frames up;
2) filled in turnover box after thin choosing peeling, to produce by the gross after transfer to drying process paving disk drying, material big gun again Toast end is spaced 4-8 hours to drying is started.
There are the problem of include:
1) strainer drug several times is used, speed is slow, low efficiency;
2) time of the boiling water Dan short activity for not killing emulsin can promote amarogentin to hydrolyze, and it is long to impregnate cooling time Amarogentin is soluble easily in water to be caused to be lost;
3) dry that amarogentin is soluble easily in water causes to be lost not in time, big gun toast operation amarogentin loss is serious, detection Qualification rate is low.
Summary of the invention
That for overcome the deficiencies in the prior art, the purpose of the present invention is to provide a kind of active constituent contents is high, low energy consumption, The small medicinal material Dan semen armeniacae amarae processing procedure of individual content difference.
The purpose of the present invention adopts the following technical scheme that realization:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) semen armeniacae amarae is put into Dan 5-5.5min in boiling water, it is disposable to take out;
2) using carefully choosing peeling after cold water shower 15-18s;
3) paving disk is dried, and shower is less than 2h to dry time interval is started.
Further, in step 1), the mode disposably taken out is disposable using the mesh screen being previously placed in heating kettle It leaches.
Further, it in step 3), is dried in 45-50 DEG C of overturning.
Compared with prior art, the beneficial effects of the present invention are:
The present invention is offerd medicine by boiling water, the Dan time increases to 5-5.5min, using cold water elution, the immediately hands such as dry Section, effectively having inactivated emulsin, amarogentin is preferably saved simultaneously;When operation, when shortening discharging and cooling Between, reduce the content difference between same batch semen armeniacae amarae individual;It is dried immediately after decortication, amygdalate water can be efficiently reduced Solution.
Detailed description of the invention
Fig. 1 is the appearance schematic diagram of embodiment 1.
Specific embodiment
In the following, being described further in conjunction with attached drawing and specific embodiment to the present invention, it should be noted that not Under the premise of conflicting, new implementation can be formed between various embodiments described below or between each technical characteristic in any combination Example.
The present invention provides a kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) semen armeniacae amarae is put into Dan 5-5.5min in boiling water, it is disposable to take out;
2) using carefully choosing peeling after cold water shower 15-18s;
3) paving disk is dried, and shower is less than 2h to dry time interval is started.
The processing procedure is used as medicine by boiling water, the Dan time by original 3-4min extends to 5-5.5min, is effectively leached Amarogentin and the damage to other effective components is few;It is disposable to take out, stablize with quality amygdalate in batch, between individual Otherness is small;It using cold water shower, on the one hand can make the shock heating quick corrugation peeling of almond peel, on the other hand, effectively shorten cooling Time can prevent amarogentin to be lost;After thin choosing peeling, in drying in 30min, the hydrolysis loss of amarogentin can be effectively reduced.
Embodiment 1:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) 25kg semen armeniacae amarae is put into the heating kettle of boiling water of 100L, preset stainless steel screen in heating kettle;Dan system 5min disposably leaches semen armeniacae amarae by stainless steel screen;
2) using carefully choosing peeling, draining after 8 DEG C of cold water shower 15s of 80L;
3) disk is spread, 48 DEG C of overturnings in baking oven is immediately fed into and dries to moisture content less than 0.5%.
Medicinal material Dan semen armeniacae amarae medicine materical crude slice appearance schematic diagram that embodiment 1 obtains as shown in Figure 1, its with preferable integrality, Meat is sparkling and crystal-clear penetrating.
Embodiment 2:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) Dan 4min in the boiling water for the 120L for putting into 25kg semen armeniacae amarae is disposably taken out by stainless steel screen;
2) using carefully choosing peeling after 5 DEG C of cold water shower 20s of 60L;
3) disk is spread, is immediately fed into 45 DEG C of heated-air dryings of baking oven to moisture content less than 0.5%.
Embodiment 3:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) Dan 6min in the boiling water for the 80L for putting into 25kg semen armeniacae amarae, from filtering and discharging of reaction kettle bottom;
2) using carefully choosing peeling after 10 DEG C of cold water shower 20s of 60L;
3) disk is spread, is immediately fed into 50 DEG C of heated-air dryings of baking oven to moisture content less than 0.5%.
Comparative example 1:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) 25kg semen armeniacae amarae is put into 80L cold water, rear Dan 4min is boiled in heating;It is disposably dripped by stainless steel screen Semen armeniacae amarae out;
2) using carefully choosing peeling after 8 DEG C of cold water shower 15s of 60L;
3) disk is spread, is immediately fed into 48 DEG C of heated-air dryings of baking oven to moisture content less than 0.5%.
Comparative example 2:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) by the heating kettle of the boiling water of 25kg semen armeniacae amarae investment 100L, bitter apricot is pulled out in batches in Dan 4min, 1.5min Benevolence;
2) using carefully choosing peeling after 80L cold water soak 3min;
3) disk is spread, is immediately fed into 50 DEG C of heated-air dryings of baking oven to moisture content less than 0.5%.
Comparative example 3:
A kind of medicinal material Dan semen armeniacae amarae processing procedure, comprising the following steps:
1) by the heating kettle of the boiling water of 25kg semen armeniacae amarae 100L, preset stainless steel screen in heating kettle;Dan 5min leads to It crosses stainless steel screen and disposably leaches semen armeniacae amarae;
2) using carefully choosing peeling after 8 DEG C of cold water shower 15s of 60L;
3) after spreading disk 6h, in 45 DEG C of heated-air dryings of baking oven to moisture content less than 0.5%.
Performance detection and effect assessment
Medicine materical crude slice made of semen armeniacae amarae after Example 1-3 and comparative example 1-3 is dry, is recorded using Chinese Pharmacopoeia 2010 editions High performance liquid chromatography detection amarogentin content.As a result as shown in the table.
Embodiment 1 Embodiment 2 Embodiment 3
Content, % 3.14 2.81 2.77
Comparative example 1 Comparative example 2 Comparative example 3
Content, % 1.86 2.48 2.29
By the comparison of upper table it is found that using method provided by the invention, the content of the amarogentin of obtained medicine materical crude slice is obvious Higher than comparative example, and in process, water consumption is few, peeling is convenient, and manpower and energy cost has been reduced to a great extent.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto, The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention Claimed range.

Claims (3)

1. a kind of medicinal material Dan semen armeniacae amarae processing procedure, which comprises the following steps:
1) semen armeniacae amarae is put into Dan 5-5.5min in boiling water, it is disposable to take out;
2) using carefully choosing peeling after cold water shower 15-18s;
3) paving disk is dried, and shower is less than 2h to dry time interval is started.
2. medicinal material Dan semen armeniacae amarae processing procedure as described in claim 1, which is characterized in that in step 1), disposably take out Mode is disposably to be leached using the mesh screen being previously placed in heating kettle.
3. medicinal material Dan semen armeniacae amarae processing procedure as described in claim 1, which is characterized in that in step 3), overturn in 45-50 DEG C Drying.
CN201811161113.4A 2018-09-30 2018-09-30 A kind of medicinal material Dan semen armeniacae amarae processing procedure Pending CN109316523A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111529580A (en) * 2020-05-21 2020-08-14 安徽昌顺药业有限公司 Processing method for scalding bitter almonds
CN112755081A (en) * 2021-02-20 2021-05-07 杨成俊 Novel economic and environment-friendly processing method of clam powder fried medicinal material bitter almonds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104706680A (en) * 2014-09-24 2015-06-17 北京康仁堂药业有限公司 Scalding processing technology
CN107468779A (en) * 2017-06-16 2017-12-15 康美药业股份有限公司 A kind of processing method of Dan peach kernels medicine materical crude slice

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104706680A (en) * 2014-09-24 2015-06-17 北京康仁堂药业有限公司 Scalding processing technology
CN107468779A (en) * 2017-06-16 2017-12-15 康美药业股份有限公司 A kind of processing method of Dan peach kernels medicine materical crude slice

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
姚东云: "《中药炮制技术》", 31 January 2016, 重庆:重庆大学出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111529580A (en) * 2020-05-21 2020-08-14 安徽昌顺药业有限公司 Processing method for scalding bitter almonds
CN112755081A (en) * 2021-02-20 2021-05-07 杨成俊 Novel economic and environment-friendly processing method of clam powder fried medicinal material bitter almonds

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Application publication date: 20190212