CN109307543A - A kind of anti-liquid-detecting that drains off for solid-phase extracting instrument - Google Patents

A kind of anti-liquid-detecting that drains off for solid-phase extracting instrument Download PDF

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Publication number
CN109307543A
CN109307543A CN201811186634.5A CN201811186634A CN109307543A CN 109307543 A CN109307543 A CN 109307543A CN 201811186634 A CN201811186634 A CN 201811186634A CN 109307543 A CN109307543 A CN 109307543A
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CN
China
Prior art keywords
solid
phase extracting
liquid
extracting instrument
height
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811186634.5A
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Chinese (zh)
Inventor
王剑
官帅
赵玉华
邓立刚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Agricultural Quality Standards and Testing Technology of Shandong Academy of Agricultural Sciences
Original Assignee
Institute of Agricultural Quality Standards and Testing Technology of Shandong Academy of Agricultural Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Institute of Agricultural Quality Standards and Testing Technology of Shandong Academy of Agricultural Sciences filed Critical Institute of Agricultural Quality Standards and Testing Technology of Shandong Academy of Agricultural Sciences
Priority to CN201811186634.5A priority Critical patent/CN109307543A/en
Publication of CN109307543A publication Critical patent/CN109307543A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)

Abstract

The invention discloses a kind of anti-liquid-detectings that drains off for solid-phase extracting instrument, SPE column is installed on the solid-phase extracting instrument, solid-phase extracting instrument is connect by gas-guide tube with press pump is taken out, including mounting rack, controller, liquid level sensor, the connection of the upper end-face edge of the mounting rack and solid-phase extracting instrument, mounting rack is equipped with multiple height fixed links, height fixed link is slidably connected with mounting rack, height fixed link is set to the side of SPE column and parallel with SPE column, the height fixed link is equipped with fixed sliding block, the fixed sliding block is equipped with liquid level sensor, the controller respectively with liquid level sensor, take out press pump electrical connection, detect the liquid height in SPE column automatically by liquid level sensor, guarantee not continuing to extract after liquid level reaches certain altitude, prevent the dried liquid stream in SPE column, which solves The problem of needing staff to monitor liquid level always at present, ensure that extracting and purifying quality, improves the accuracy of experimental data.

Description

A kind of anti-liquid-detecting that drains off for solid-phase extracting instrument
Technical field
The present invention relates to experimental instrument technology, specially a kind of anti-liquid detecting dress that drains off for solid-phase extracting instrument It sets.
Background technique
Solid Phase Extraction is exactly to be adsorbed the target compound in fluid sample using solid absorbent, with the matrix of sample and Interfering compound separation, then uses elution or heating desorption again, achievees the purpose that separation and enrichment target compound.
When using solid-phase extracting instrument, fluid sample is added in SPE column, SPE column is then inserted in solid-phase extracting instrument On the connector of upper end, accelerate the extraction of liquid in SPE column by pressurizeing or taking out negative pressure, during the experiment due to staff It is busier or it is interim it is busy go out to will lead to the dried liquid stream in SPE column, cause clean-up effect to reduce, influence experiment knot Fruit, it is therefore desirable to which the liquid height that staff is stared at constantly in SPE column prevents the phenomenon that drains off, and causes staff can not Other work are carried out, working efficiency is reduced.
Summary of the invention
The present invention provides a kind of anti-liquid that drains off for solid-phase extracting instrument aiming at deficiencies of the prior art Body detection device, the installation detecting device on solid-phase extracting instrument, the liquid detected automatically in SPE column by liquid level sensor are high Degree, when liquid level reaches setting height, controller, which can automatically control to take out press pump and power off, to be stopped taking out pressure, guarantees that liquid level arrival is certain high It does not continue to extract after degree, it is therefore prevented that the dried liquid stream in SPE column, which solves need staff to monitor always at present The problem of liquid level, the constraint to staff is broken, staff can carry out other work in extraction process, mention High working efficiency, while dried liquid stream problem is avoided, it ensure that extracting and purifying quality, improve the accurate of experimental data Property.
To achieve the above object, invention provides the following technical solutions:
A kind of anti-liquid-detecting that drains off for solid-phase extracting instrument is equipped with SPE column on the solid-phase extracting instrument, Gu Phase abstraction instrument is connect by gas-guide tube with press pump is taken out, including mounting rack, controller, liquid level sensor, the mounting rack and solid phase The upper end-face edge of abstraction instrument connects, and mounting rack is equipped with multiple height fixed links, and height fixed link is slidably connected with mounting rack, high It spends fixed link and is set to the side of SPE column and parallel with SPE column, the height fixed link is equipped with fixed sliding block, described fixed sliding Block is equipped with liquid level sensor, and the controller is electrically connected with liquid level sensor, pumping press pump respectively.
Preferably, the mounting rack includes adjustable shelf, fixed frame, the fixed frame include fixing clip, the second connecting rod, Crossbeam, the crossbeam are arranged along the length direction of solid-phase extracting instrument, and crossbeam is set to the side of solid-phase extracting instrument, second connection Bar is arranged along the width direction of solid-phase extracting instrument, and one end of second connecting rod is connect with fixing clip, the second connecting rod The other end is vertical with one end of crossbeam to be connected, and the adjustable shelf includes movable clip block, first connecting rod, lantern ring, first connecting rod Parallel with the second connecting rod, one end of the first connecting rod is connect with movable clip block, the other end and lantern ring of first connecting rod Connection, the lantern ring are socketed on crossbeam, and lantern ring is equipped with clamping screw, and lantern ring and crossbeam are fixed by clamping screw.
Preferably, it is equipped with card slot on the inside of the movable clip block and fixing clip, the card slot and solid-phase extracting instrument Edge mate.
Preferably, the end of the crossbeam is equipped with horizontal stop block.
Preferably, the upper end side of the first connecting rod is vertically equipped with first support bar, the upper end of first support bar with Lantern ring connection, the upper end side of second connecting rod are vertically equipped with second support bar, the upper end of the second support bar and cross Beam connection, first support bar are identical as the height of second support bar.
Preferably, the upper end of the height fixed link is equipped with height limit block, and the side wall of the height fixed link is equipped with The lower end of graduation mark, height fixed link is equipped with sliding sleeve, the sliding sleeve and beam engagement.
Preferably, the fixed sliding block includes connecting plate, clamping plate, buckle, and the both ends of the connecting plate are connected with clamping plate, and two Block clamping plate is parallel to each other, and height fixed link is set between two clamping plates, and the inside of clamping plate is equipped with limit plate, the inner sidewall of limit plate It is connect with height fixed link, the end of two clamping plates is connected by threaded rod, and threaded rod is equipped with nut, one of clamping plate Side with snap connection, the buckle is connect with liquid level sensor.
Preferably, the liquid level sensor is capacitive approach switch.
Preferably, the controller is the single-chip microcontroller of model stm32f103, and controller is equipped with combined aural and visual alarm.
Compared with prior art, advantageous effect of the invention is:
1, present invention installation detecting device on solid-phase extracting instrument, the liquid in SPE column is detected by liquid level sensor automatically Body height, when liquid level reaches setting height, controller, which can automatically control, takes out press pump power-off stopping pumping pressure, guarantees that liquid level reaches one It does not continue to extract after determining height, it is therefore prevented that the dried liquid stream in SPE column, which solves need staff always at present The problem of monitoring liquid level, has broken the constraint to staff, staff can carry out other works in extraction process Make, improves work efficiency, while avoiding dried liquid stream problem, ensure that extracting and purifying quality, improve experimental data Accuracy.
2, mounting rack of the invention in use, is adjusted between movable clip block and fixing clip by sliding adjustable shelf Distance, be installed on various sizes of solid-phase extracting instrument so as to will test device, increase the versatility that device uses, Installation process is convenient, simple, quick, is fixed by clamping screw, guarantees secured, reliable in use process.
3, the present invention is respectively provided with card slot on the inside of fixing clip and movable clip block, directly the edge card of solid-phase extracting instrument Enter connection, prevents from slipping, use is relatively reliable.
4, horizontal stop block is arranged on crossbeam and can prevent from sliding in use process adjustable shelf and height fixed link by the present invention Crossbeam out, while can prevent when not in use, adjustable shelf and height fixed link are lost, and guarantee the integrality of equipment.
5, the present invention increases beam height by setting first support bar and second support bar, and it is fixed can to shorten height The height of bar, while guaranteeing the bottom that SPE column is able to detect that when liquid level sensor slides into bottom.
6, the present invention can prevent fixed sliding block from slipping in the upper end of height fixed link setting height limit block, guarantee to use In equipment safety, height fixed link lower end be arranged sliding sleeve, convenient for adjust height fixed link horizontal position, regulative mode Simply, conveniently.
7, limit plate is arranged in the present invention on the inside of clamping plate, on the one hand can play the role of being fixedly clamped to height fixed link, It can guarantee that fixed sliding block can only do upper and lower sliding along height fixed link simultaneously, while be pressed from both sides using nut and threaded rod to two When plate is locked, the curvature of clamping plate can be limited, prevent nut from tightening more degree damage clamping plates.
8, combined aural and visual alarm is arranged in the present invention on the controller, when liquid level reaches liquid level sensor detection position, control Device can control combined aural and visual alarm and issue alarm signal, remind staff, more convenient to use.
Detailed description of the invention
Fig. 1 is the structural schematic diagram one that the present invention is mounted on solid-phase extracting instrument;
Fig. 2 is the structural schematic diagram two that the present invention is mounted on solid-phase extracting instrument;
Fig. 3 is structural schematic diagram of the invention;
Fig. 4 is the structural schematic diagram of fixed sliding block;
Fig. 5 is adjustable shelf structural schematic diagram;
Fig. 6 is height fixed rod structure schematic diagram.
In figure: 1- solid-phase extracting instrument;2-SPE column;3- liquid level sensor;4- mounting rack;5- controller;6- height is fixed Bar;601- height limit block;602- graduation mark;603- sliding sleeve;7- fixes sliding block;701- connecting plate;702- clamping plate;703- spiral shell It is female;704- threaded rod;705- limit plate;706- buckle;8- adjustable shelf;801- movable clip block;802- first connecting rod;803- set Ring;804- clamping screw;805- first support bar;9- fixed frame;901- second support bar;The second connecting rod of 902-;903- is solid Clamp block;904- crossbeam;905- horizontal stop block.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
As shown in Figure 1, 2, a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument, on the solid-phase extracting instrument 1 SPE column 2 is installed, solid-phase extracting instrument 1 is connect by gas-guide tube with press pump is taken out, including mounting rack 4, controller 5, liquid level sensor 3, the mounting rack 4 is connect with the upper end-face edge of solid-phase extracting instrument 1, and mounting rack 4 is equipped with multiple height fixed links 6, and height is solid Fixed pole 6 is slidably connected with mounting rack 4, and height fixed link 6 is set to the side of SPE column 2 and parallel with SPE column 2, and the height is fixed Bar 6 is equipped with fixed sliding block 7, and the fixed sliding block 7 is equipped with liquid level sensor 3, the controller 5 respectively with liquid level sensor 3, press pump electrical connection is taken out, the liquid level sensor 5 is capacitive approach switch, and the controller 5 is model stm32f103 Single-chip microcontroller, controller 5 are equipped with combined aural and visual alarm.When liquid level reaches liquid level sensor 3 and detects position, controller 5 can be controlled Combined aural and visual alarm issues alarm signal, reminds staff, more convenient to use.
As shown in figure 3, the mounting rack 4 include adjustable shelf 8, fixed frame 9, the fixed frame 9 include fixing clip 903, Second connecting rod 902, crossbeam 904, the crossbeam 904 are arranged along the length direction of solid-phase extracting instrument 1, and crossbeam 904 is set to solid phase The side of abstraction instrument 1, second connecting rod 902 are arranged along the width direction of solid-phase extracting instrument 1, second connecting rod 902 One end connect with fixing clip 903, the other end of the second connecting rod 902 is vertical with one end of crossbeam 904 to be connect, crossbeam 904 The other end be equipped with horizontal stop block 905, can prevent from skidding off crossbeam 904 in use process adjustable shelf 8 and height fixed link 6, It can prevent when not in use simultaneously, adjustable shelf 8 and height fixed link 6 are lost, and guarantee the integrality of equipment.As shown in figure 5, institute Stating adjustable shelf 8 includes movable clip block 801, first connecting rod 802, lantern ring 803, and first connecting rod 802 and the second connecting rod 902 are flat Row, one end of the first connecting rod 802 are connect with movable clip block 801, and the other end and lantern ring 803 of first connecting rod 802 connect It connects, the lantern ring 803 is socketed on crossbeam 904, and lantern ring 803 is equipped with clamping screw 804, and lantern ring 803 and crossbeam 904 pass through lock Tight bolt 804 is fixed, and the movable clip block 801 and the inside of fixing clip 903 are equipped with card slot, the card slot and Solid Phase Extraction The edge of solid-phase extracting instrument 1 is directly caught in connection by the edge mate of instrument 1, prevents from slipping, use is relatively reliable.Mounting rack 4 exists In use process, the distance between movable clip block 801 and fixing clip 903 are adjusted by sliding adjustable shelf 8, so as to examine Survey device to be installed on various sizes of solid-phase extracting instrument, increase the versatility that device uses, installation process is convenient, it is simple, Quickly, it is fixed, is guaranteed secured, reliable in use process by clamping screw 804.
The upper end side of the first connecting rod 802 is vertically equipped with first support bar 805, the upper end of first support bar 805 It is connect with lantern ring 803, the upper end side of second connecting rod 902 is vertically equipped with second support bar 901, the second support bar 901 upper end is connect with crossbeam 904, and first support bar 805 is identical as the height of second support bar 901.
As shown in fig. 6, the upper end of the height fixed link 6 is equipped with height limit block 601, the side of the height fixed link 6 Wall is equipped with graduation mark 602, and the lower end of height fixed link 6 is equipped with sliding sleeve 603, and the sliding sleeve 603 cooperates with crossbeam 904.
As shown in figure 4, the fixed sliding block 7 includes connecting plate 701, clamping plate 702, buckles 706, the connecting plate 701 Both ends are connected with clamping plate 702, and two clamping plates 702 are parallel to each other, and height fixed link 6 is set between two clamping plates 702, clamping plate 702 Inside be equipped with limit plate 705, the inner sidewall of limit plate 705 connect with height fixed link 6, on the one hand can be to height fixed link 6 play the role of being fixedly clamped, while can guarantee that fixed sliding block 7 can only do upper and lower sliding, two clamping plates along height fixed link 6 702 end is connected by threaded rod 704, and threaded rod 704 is equipped with nut 703, is using nut 703 and threaded rod 704 When being locked to two clamping plates 702, the curvature of clamping plate 702 can be limited, prevent nut 703 from tightening more degree damage folders Plate 702.The side of one of clamping plate 702 is connect with buckle 706, and the buckle 706 is connect with liquid level sensor 3.
It is fixing clip 903 upper with solid-phase extracting instrument 1 in use, first connect mounting rack 4 with solid-phase extracting instrument 1 End margin connection, crossbeam 904 are arranged along the length direction of solid-phase extracting instrument 1, slide adjustable shelf 8, make movable clip block 801 and solid phase The upper end-face edge of abstraction instrument 1 is clamped, and then tightens clamping screw 804 and the position of adjustable shelf 8 is fixed, then sliding height Fixed link 6 makes liquid level sensor 3 be directed at SPE column 2, and a liquid level sensor 3 is directed at one, then by sliding fixed sliding block 7 The height of liquid level sensor 3 is adjusted, it is by tightening nut 703 that clamping plate 702 is fixed after setting height, it starts switch Start to extract, after the liquid in SPE column 2 is that height drops to the setting height of liquid level sensor 3,3 meeting of liquid level sensor at this time Signal is transmitted to controller 5, controller 5, which is closed, takes out press pump switch stopping pumping pressure, while alerting signal occurs for combined aural and visual alarm, mentions Staff's extraction of waking up finishes, and guarantees not continuing to extract after liquid level reaches certain altitude, it is therefore prevented that the liquid flow in SPE column 2 It is dry, which solves needing staff to monitor liquid level always at present, break the constraint to staff, Staff can carry out other work in extraction process, improve work efficiency, while avoid dried liquid stream problem, protect Extracting and purifying quality has been demonstrate,proved, the accuracy of experimental data is improved.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art Mind and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies Within, then the present invention is also intended to include these modifications and variations.

Claims (9)

1. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument, SPE column, solid phase are installed on the solid-phase extracting instrument Abstraction instrument is connect by gas-guide tube with press pump is taken out, it is characterised in that: including mounting rack, controller, liquid level sensor, the installation The connection of the upper end-face edge of frame and solid-phase extracting instrument, mounting rack are equipped with multiple height fixed links, and height fixed link and mounting rack are sliding Dynamic connection, height fixed link are set to the side of SPE column and parallel with SPE column, and the height fixed link is equipped with fixed sliding block, institute Fixed sliding block is stated equipped with liquid level sensor, the controller is electrically connected with liquid level sensor, pumping press pump respectively.
2. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as described in claim 1, it is characterised in that: described Mounting rack includes adjustable shelf, fixed frame, and the fixed frame includes fixing clip, the second connecting rod, crossbeam, and the crossbeam is along solid phase The length direction of abstraction instrument is arranged, and crossbeam is set to the side of solid-phase extracting instrument, width of second connecting rod along solid-phase extracting instrument Direction setting is spent, one end of second connecting rod is connect with fixing clip, the other end of the second connecting rod and one end of crossbeam Vertical connection, the adjustable shelf includes movable clip block, first connecting rod, lantern ring, and first connecting rod is parallel with the second connecting rod, institute The one end for stating first connecting rod is connect with movable clip block, and the other end of first connecting rod is connect with lantern ring, and the lantern ring is socketed in On crossbeam, lantern ring is equipped with clamping screw, and lantern ring and crossbeam are fixed by clamping screw.
3. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 2, it is characterised in that: described Card slot, the edge mate of the card slot and solid-phase extracting instrument are equipped on the inside of movable clip block and fixing clip.
4. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 2, it is characterised in that: described The end of crossbeam is equipped with horizontal stop block.
5. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 2, it is characterised in that: described The upper end side of first connecting rod is vertically equipped with first support bar, and the upper end of first support bar is connect with lantern ring, and described second connects The upper end side of extension bar is vertically equipped with second support bar, and the upper end of the second support bar is connect with crossbeam, first support bar with The height of second support bar is identical.
6. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 2, it is characterised in that: described The upper end of height fixed link is equipped with height limit block, and the side wall of the height fixed link is equipped with graduation mark, height fixed link Lower end is equipped with sliding sleeve, the sliding sleeve and beam engagement.
7. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 6, it is characterised in that: described Fixed sliding block includes connecting plate, clamping plate, buckle, and the both ends of the connecting plate are connected with clamping plate, and two clamping plates are parallel to each other, height Fixed link is set between two clamping plates, and the inside of clamping plate is equipped with limit plate, and the inner sidewall of limit plate is connect with height fixed link, and two The end of block clamping plate by threaded rod connect, and threaded rod be equipped with nut, the side of one of clamping plate with snap connection, institute Buckle is stated to connect with liquid level sensor.
8. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as claimed in claim 7, it is characterised in that: described Liquid level sensor is capacitive approach switch.
9. a kind of anti-liquid-detecting that drains off for solid-phase extracting instrument as described in claim 1, it is characterised in that: described Controller is the single-chip microcontroller of model stm32f103, and controller is equipped with combined aural and visual alarm.
CN201811186634.5A 2018-10-12 2018-10-12 A kind of anti-liquid-detecting that drains off for solid-phase extracting instrument Pending CN109307543A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112245970A (en) * 2020-09-16 2021-01-22 金华市农产品质量安全中心(金华市农业综合检验检测中心) Anti-shaking solid-phase extraction rack

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112245970A (en) * 2020-09-16 2021-01-22 金华市农产品质量安全中心(金华市农业综合检验检测中心) Anti-shaking solid-phase extraction rack

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