CN109280038A - A kind of synthetic method of Sensiva SC50 ether - Google Patents
A kind of synthetic method of Sensiva SC50 ether Download PDFInfo
- Publication number
- CN109280038A CN109280038A CN201811081954.4A CN201811081954A CN109280038A CN 109280038 A CN109280038 A CN 109280038A CN 201811081954 A CN201811081954 A CN 201811081954A CN 109280038 A CN109280038 A CN 109280038A
- Authority
- CN
- China
- Prior art keywords
- isooctanol
- sensiva
- ether
- sodium
- epoxychloropropane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Abstract
The invention proposes a kind of synthetic methods of Sensiva SC50 ether comprising: isooctanol and sodium hydroxide are put into in container and heating, are stirred continuously in heating process, then negative pressure is dehydrated, to obtain isooctanol sodium solution；25~30 DEG C are cooled to, epoxychloropropane is added to the isooctanol sodium solution, and keeps the temperature 0.8-1.2 hours, slowly heating is to obtain Sensiva SC50 ether.Compared with prior art, the synthetic method of Sensiva SC50 ether provided by the invention, which has the following technical effect that, directly synthesizes target product using isooctanol sodium and epoxychloropropane, its reaction step is few, process route is short, and impurity and waste water will not be generated in synthesis process, it not only ensure that the quality of target product, but also reduce the pollution to environment.
Description
Technical field
The present invention relates to the field of chemical synthesis more particularly to a kind of synthetic methods of Sensiva SC50 ether.
Background technique chemistry
In the prior art, Sensiva SC50 ether first uses catalyst by ring generally using epoxychloropropane as raw material
Oxygen chloropropane open loop forms all intermediates by condensation, and then plus alkali closed loop forms glycerin ether.
There are reaction steps to cross for production technology in the prior art, process route is long, and is easy to produce in target product miscellaneous
Matter, to reduce the quality of target product.
Summary of the invention
In order to solve the above technical problems, the invention proposes a kind of synthetic method of completely new Sensiva SC50 ether,
Target product is directly synthesized using isooctanol sodium and epoxychloropropane, synthetic method craft of the invention is simple and will not generate
Impurity.
The specific technical solution of the present invention is as follows:
A kind of synthetic method of Sensiva SC50 ether comprising:
Isooctanol and sodium hydroxide are put into in container and heating, are stirred continuously in heating process, then negative pressure is dehydrated,
To obtain isooctanol sodium solution；
25~30 DEG C are cooled to, epoxychloropropane is added to the isooctanol sodium solution, and it is small to keep the temperature 0.8-1.2
When, slowly heating is to obtain Sensiva SC50 ether.
In a specific embodiment, the isooctanol, the sodium hydroxide mass ratio be 39:4.
Compared with prior art, the synthetic method of Sensiva SC50 ether provided by the invention has the following technical effect that
Target product is directly synthesized using isooctanol sodium and epoxychloropropane, reaction step is few, process route is short, and in synthesis process
Impurity and waste water will not be generated, not only ensure that the quality of target product, but also reduces the pollution to environment.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, With reference to embodiment
The present invention is described in further detail.
The present invention provides a kind of synthetic methods of Sensiva SC50 ether comprising:
Isooctanol and sodium hydroxide are put into container, and heating stirring is to obtain isooctanol sodium；
25~30 DEG C are cooled to, epoxychloropropane is added to the isooctanol sodium solution, and it is small to keep the temperature 0.8-1.2
When, slowly heating is to obtain Sensiva SC50 ether.
Wherein, further include negative pressure water removal phase to isooctanol sodium solution, to remove moisture therein.
The isooctanol, the sodium hydroxide mass ratio be 39:4.
Embodiment 1
195g isooctanol is added to flask, 20g sodium hydroxide is then added, heats and stirs, then carry out negative pressure
Dehydration, so that sodium hydroxide and isooctanol fully reacting, obtain isooctanol sodium solution.Then isooctanol sodium solution is cooled to 25
DEG C, and 46.25g epoxychloropropane is added, 1.2 hours are kept the temperature, is then slowly heated up until isooctanol sodium drop and epoxychloropropane
Fully reacting obtains Sensiva SC50 ether target product.
Embodiment 2
195g isooctanol is added to flask, 20g sodium hydroxide is then added, heats and stirs, then carry out negative pressure
Dehydration, so that sodium hydroxide and isooctanol fully reacting, obtain isooctanol sodium solution.Then isooctanol sodium solution is cooled to 28
DEG C, and 46.25g epoxychloropropane is added, 1 hour is kept the temperature, is then slowly heated up until isooctanol sodium drop is anti-with epoxychloropropane
Sensiva SC50 ether target product should be obtained completely.
Embodiment 3
195g isooctanol is added to flask, 20g sodium hydroxide is then added, heats and stirs, then carry out negative pressure
Dehydration, so that sodium hydroxide and isooctanol fully reacting, obtain isooctanol sodium solution.Then isooctanol sodium solution is cooled to 30
DEG C, and 46.25g epoxychloropropane is added, 0.8 hour is kept the temperature, is then slowly heated up until isooctanol sodium drop and epoxychloropropane
Fully reacting obtains Sensiva SC50 ether target product.
In the various embodiments described above, isooctanol and the reaction equation that the reacted dehydration of sodium hydroxide generates isooctanol sodium are as follows:
Into isooctanol sodium be added dropwise epoxychloropropane obtain iso-octyl glycidyl ether reaction equation it is as follows:
The description with certain particularity detailed enough has been carried out to the present invention above.Ordinary skill in fields
Personnel are it should be understood that the description in embodiment is only exemplary, before without departing from true spirit and scope of the present invention
Put make it is all change all should belong to protection scope of the present invention.Scope of the present invention is by the power
What sharp claim was defined, rather than limited by the foregoing description in embodiment.
Claims (2)
1. a kind of synthetic method of Sensiva SC50 ether, characterized in that it comprises:
Isooctanol and sodium hydroxide are put into in container and heating, are stirred continuously in heating process, then negative pressure is dehydrated, to obtain
Obtain isooctanol sodium solution；
25~30 DEG C are cooled to, epoxychloropropane is added to the isooctanol sodium solution, and keeps the temperature 0.8-1.2 hours, is delayed
Slow heating is to obtain Sensiva SC50 ether.
2. the synthetic method of Sensiva SC50 ether as described in claim 1, which is characterized in that the isooctanol, the hydrogen
The mass ratio of sodium oxide molybdena is 39:4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811081954.4A CN109280038A (en) | 2018-09-17 | 2018-09-17 | A kind of synthetic method of Sensiva SC50 ether |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811081954.4A CN109280038A (en) | 2018-09-17 | 2018-09-17 | A kind of synthetic method of Sensiva SC50 ether |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109280038A true CN109280038A (en) | 2019-01-29 |
Family
ID=65180905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811081954.4A Pending CN109280038A (en) | 2018-09-17 | 2018-09-17 | A kind of synthetic method of Sensiva SC50 ether |
Country Status (1)
| Country | Link |
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| CN (1) | CN109280038A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112759507A (en) * | 2020-12-21 | 2021-05-07 | 陕西省石油化工研究设计院 | Method for preparing ethylhexyl glycerol |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54115307A (en) * | 1978-02-24 | 1979-09-07 | Kanebo Ltd | Preparation of alkyl glycidyl ether |
| JPS56108781A (en) * | 1980-02-01 | 1981-08-28 | Kao Corp | Preparation of glycidyl ether |
| US20020004605A1 (en) * | 2000-05-01 | 2002-01-10 | Korea Research Institute Of Chemical Technology | Method of synthesizing glycidyl ether compounds in the absence of water and organic solvents |
-
2018
- 2018-09-17 CN CN201811081954.4A patent/CN109280038A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54115307A (en) * | 1978-02-24 | 1979-09-07 | Kanebo Ltd | Preparation of alkyl glycidyl ether |
| JPS56108781A (en) * | 1980-02-01 | 1981-08-28 | Kao Corp | Preparation of glycidyl ether |
| US20020004605A1 (en) * | 2000-05-01 | 2002-01-10 | Korea Research Institute Of Chemical Technology | Method of synthesizing glycidyl ether compounds in the absence of water and organic solvents |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112759507A (en) * | 2020-12-21 | 2021-05-07 | 陕西省石油化工研究设计院 | Method for preparing ethylhexyl glycerol |
| CN112759507B (en) * | 2020-12-21 | 2023-05-26 | 陕西省石油化工研究设计院 | Preparation method of ethylhexyl glycerol |
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Application publication date: 20190129 |