CN109259856A - Radio frequency heating probe device and radio frequency ablation equipment - Google Patents
Radio frequency heating probe device and radio frequency ablation equipment Download PDFInfo
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- CN109259856A CN109259856A CN201811061136.8A CN201811061136A CN109259856A CN 109259856 A CN109259856 A CN 109259856A CN 201811061136 A CN201811061136 A CN 201811061136A CN 109259856 A CN109259856 A CN 109259856A
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- 239000000523 sample Substances 0.000 title claims abstract description 125
- 238000010438 heat treatment Methods 0.000 title claims abstract description 37
- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 35
- 229910001338 liquidmetal Inorganic materials 0.000 claims abstract description 32
- 238000005086 pumping Methods 0.000 claims abstract description 22
- 238000005452 bending Methods 0.000 claims abstract description 10
- 239000003814 drug Substances 0.000 claims description 19
- 229940079593 drug Drugs 0.000 claims description 13
- 238000012377 drug delivery Methods 0.000 claims description 12
- 238000012545 processing Methods 0.000 claims description 12
- 230000001105 regulatory effect Effects 0.000 claims description 10
- 230000033228 biological regulation Effects 0.000 claims description 7
- 230000001276 controlling effect Effects 0.000 claims description 4
- 229910000846 In alloy Inorganic materials 0.000 claims description 3
- 229910001128 Sn alloy Inorganic materials 0.000 claims description 3
- 238000009413 insulation Methods 0.000 claims description 3
- 230000009123 feedback regulation Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 1
- 238000001816 cooling Methods 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 230000008859 change Effects 0.000 abstract description 2
- 230000007797 corrosion Effects 0.000 abstract 1
- 238000005260 corrosion Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 10
- 206010003658 Atrial Fibrillation Diseases 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 230000006870 function Effects 0.000 description 6
- 238000002679 ablation Methods 0.000 description 5
- 239000012267 brine Substances 0.000 description 5
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 5
- 238000013153 catheter ablation Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000002651 drug therapy Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 230000010412 perfusion Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000003763 carbonization Methods 0.000 description 2
- 239000000110 cooling liquid Substances 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- 229910018487 Ni—Cr Inorganic materials 0.000 description 1
- 206010049447 Tachyarrhythmia Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- VNNRSPGTAMTISX-UHFFFAOYSA-N chromium nickel Chemical compound [Cr].[Ni] VNNRSPGTAMTISX-UHFFFAOYSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000013546 non-drug therapy Methods 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- -1 polytetrafluoroethylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000012781 shape memory material Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
- A61B2018/00583—Coblation, i.e. ablation using a cold plasma
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Otolaryngology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The embodiment of the invention provides a radio frequency heating probe device and radio frequency ablation equipment, wherein the radio frequency heating probe device comprises: the probe comprises a probe head, liquid metal, a flexible probe conduit, a curvature adjusting part, a heat exchange part and a pumping part, wherein the liquid metal circularly flows in a loop formed by a flexible liquid inlet conduit, the probe head, a flexible liquid outlet conduit and the heat exchange part under the driving of the pumping part, and the curvature adjusting part is arranged in the flexible probe conduit and used for adjusting the curvature of the flexible probe conduit. According to the radio-frequency heating probe device and the radio-frequency ablation equipment provided by the embodiment of the invention, the flexible and bendable probe tube structure is adopted, and the bending degree of the probe tube is controlled through the temperature change of the resistance wire, so that the radio-frequency heating probe device and the radio-frequency ablation equipment can be better adapted to the heart environment of a human body; meanwhile, the liquid metal circulates in the guide pipe, the temperature of the probe head is effectively prevented from being too high, and the corrosion effect of the traditional cooling working medium on the probe head can be avoided.
Description
Technical field
The present embodiments relate to electricity to melt medical instruments field, more particularly, to a kind of radio frequency heating probe unit
And radio frequency ablation device.
Background technique
Heart atrial fibrillation is a kind of common tachy-arrhythmia illness, incidence with advancing age and gradually on
It rises.In the treatment of heart atrial fibrillation, drug therapy is a kind of common treatment means, it can alleviate disease to a certain extent
Shape also avoids the pain of patients surgery.But many times, the effect is unsatisfactory for drug therapy.And some atrial fibrillations are suffered from
Person cannot mitigate slight illness by the means of drug therapy due to various reasons.With the development of science and technology, non-drug therapy
Method is increasingly becoming emphasis concerned by people.Currently, most common method is in the non-pharmaceutical method for the treatment of heart atrial fibrillation
Radiofrequency catheter ablation, it has become one of radical cure paroxysmal heart atrial fibrillation most efficient method.Radiofrequency catheter ablation also because
Its highly-safe, few intercurrent disease, the advantages that effect is obvious, minimally invasive, are used widely in heart atrial fibrillation therapy.
In RF ablation, the heat of end of probe is exported as the increase of distance can rapid decrease.In clinical operation, it is
So that energy is exported at a distance, usually can be due to temperature excessively high and cause probe surrounding tissue to be carbonized, this is unfavorable for heart
The operation of the opposite fines such as atrial fibrillation.Also, the carbonization of probe surrounding tissue can also impact probe energy input, in turn
Influence therapeutic effect.Cold brine perfusion radiofrequency catheter can improve the excessively high caused carbonization problem of temperature.It passes through in probe
The micro perfusion hole injection correct termination electrode of cool brine of portion's setting is cooled down, to improve power output and reduce thrombus shape
At.
In this pouring type radiofrequency catheter device, the cooling working medium being related to is cool brine as coolant liquid, however this
Kind device will limit its function and effect there are certain disadvantage.The thermal conductivity of one side cool brine itself is not high, on the other hand
The metal material of its correct termination electrode of meeting during prolonged use slowly corrodes, and influences the electromagnetic wave energy of probe head end
Output performance, and then influence successive treatment effect.
In addition, RF catheter ablation operation in, conduit enter in heart need certain bending get to need
The specific site to be melted, but current some radiofrequency catheters, flexibility is not high, and bending degree is undesirable, in openheart surgery
In, especially ablative surgery, needing more accurately to bend makes conduit reach specified ablation site.
Summary of the invention
(1) technical problems to be solved
The purpose of the embodiment of the present invention is that providing a kind of radio frequency heating probe unit and RF ablation probe, solve existing
Radio frequency heating probe unit in not high, the perishable disadvantage of cooling working medium conductivity, while also achieving the spirit of probe device
Moving bend folding, improves the working efficiency and the scope of application of equipment.
(2) technical solution
In order to solve the above-mentioned technical problem, according to an aspect of an embodiment of the present invention, a kind of radio frequency heating probe is provided
Device, comprising: probe, liquid metal, flexible stylet conduit, curvature regulating member, heat exchanger components and pumping member, institute
The connecting pin for stating probe is separately connected flexible liquid inlet conduit and flexible eluate conduit, the flexible stylet conduit and the spy
The connecting pin of syringe needle is fixedly connected, and the flexibility liquid inlet conduit and flexible eluate conduit are nested in the flexible stylet conduit
Portion, it is described flexibility eluate conduit outlet end be connected to the arrival end of the heat exchanger components, the outlet end of the heat exchanger components and
The arrival end connection of the flexibility liquid inlet conduit, the pumping member are installed in the flexible liquid inlet conduit, the liquid gold
Belong under the driving of the pumping member through the flexible liquid inlet conduit, probe, flexible eluate conduit and heat exchanger components group
At circuit in circulate, the curvature regulating member is embedded in the flexible stylet conduit and described soft for adjusting
The curvature of property probe catheter.
Preferably, the curvature regulating member includes: more resistance wires, the more resistance wire parallel connection electrical connections and edge
The axially spaced-apart of the flexible stylet conduit is arranged, and shape memory member is equipped between adjacent two resistance wires, described soft
Property probe catheter be equipped with for control every resistance wire autonomous working regulation button.
Preferably, the flexible stylet conduit is equipped with probe handle, the regulation button far from one end of the probe
It is installed in the probe handle.
Preferably, the feed liquor circulation conduit and outside of liquid circulation conduit is enclosed with thermal insulation layer out.
Preferably, the pumping member is micro fluidic device, and it is soft that drug conveying is also nested in the flexible stylet conduit
Pipe, the outlet end of the drug delivery hose are located at the transmitting terminal of the probe, the arrival end of the drug delivery hose and
The micro fluidic device is connected to, and is also connected with medicine storing bag on the micro fluidic device, the drug in the medicine storing bag is described micro-
Outlet end outflow under the driving of flow control apparatus through the drug delivery hose.
Preferably, the liquid metal is gallium-indium alloy or gallium-indium-tin alloy.
Preferably, the transmitting terminal of the probe is equipped with miniature webcam and LED light source.
Preferably, the radio frequency heating probe unit further include: fan, the fan outer cover is equipped with radome fairing, described
The setting of heat exchanger components described in the face of fan position.
According to another aspect of an embodiment of the present invention, a kind of radio frequency ablation device is provided, comprising: auxiliary electrode, radio frequency hair
Radio frequency heating probe unit described in generating apparatus and first aspect of the embodiment of the present invention, the radio frequency generator, which is equipped with, to be used
In the RF energy output port for connecting liquid metal in the auxiliary electrode and the radio frequency heating probe unit.
Preferably, radio frequency ablation device further include: data acquisition processing device, the transmitting terminal of the probe with it is described soft
Property probe catheter side wall be equipped with multiple temperature sensors, the pumping member, fan, radio frequency generator and multiple temperature
Degree sensor is electrically connected with the data acquisition processing device, and the data acquisition processing device is passed according to the multiple temperature
The revolving speed of the power of pumping member, the frequency of radio frequency generator and fan described in the temperature data feedback regulation of sensor.
(3) beneficial effect
Radio frequency heating probe unit and radio frequency ablation device provided in an embodiment of the present invention, using the probe of flexible bendable
Pipe structure, and changed by the temperature of resistance wire to control the bending degree of probe tube, the heart of human body can be better adapted to
Dirty environment；Simultaneously by circulation of the liquid metal in conduit, effectively prevents probe temperature excessively high, tradition can also be avoided
Corrosiveness of the working medium that cools down for probe.
In addition, the medical camera and LED light source of probe head end, can provide visualization function, determine that conduit exists in real time
The completion quality of operation can be improved in position in heart.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is the present invention
Some embodiments for those of ordinary skill in the art without creative efforts, can also basis
These attached drawings obtain other attached drawings.
Fig. 1 is the structural schematic diagram of radio frequency heating probe in the embodiment of the present invention；
Fig. 2 is the internal structure chart of flexible stylet conduit in the embodiment of the present invention；
Fig. 3 is the sectional view of flexible liquid inlet conduit in the embodiment of the present invention；
Fig. 4 is the structural schematic diagram of radio frequency heating probe in another embodiment of the present invention；
Fig. 5 is the internal structure chart of flexible stylet conduit in another embodiment of the present invention；
Fig. 6 is the connection schematic diagram of radio frequency ablation device in the embodiment of the present invention；
Appended drawing reference:
1- probe；2- resistance wire；3- shape memory member；4- flexible stylet conduit；5- probe handle；6- adjusting is pressed
Button；7- pumping member；8- heat exchanger components；9- liquid metal；10- radio frequency generator；11- miniature webcam；12-LED light source；
13- data acquisition processing device；14- fan；15- radome fairing；16- computer；17- auxiliary electrode；18- temperature sensor；19-
Medicine storing bag；401- flexibility liquid inlet conduit；402- flexibility eluate conduit；403- drug delivery hose；404- insulating layer.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Implement below
Example is not intended to limit the scope of the invention for illustrating the present invention.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
To be mechanical connection, it is also possible to be electrically connected；It can be directly connected, can also can be indirectly connected through an intermediary
Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition
Concrete meaning in invention.
As shown in Figure 1 to Figure 3, the embodiment of the present invention provides a kind of radio frequency heating probe unit, specifically includes: probe 1,
Liquid metal 9, flexible stylet conduit 4, curvature regulating member, heat exchanger components 8 and pumping member 7.
Wherein, probe 1 can choose stainless steel production, and on the one hand it has certain hardness, and on the other hand it has good
Good electric conductivity.Probe 1 divides for transmitting terminal and connecting pin, and transmitting terminal is used for ablation process, connecting pin with thermal energy is generated
For fixed support and connect circulating cooling liquid.Specifically, probe 1 is equipped with liquid metal chamber close to the position of connecting pin
101, liquid metal chamber is connected to flexible liquid inlet conduit 401 and flexible eluate conduit 402, flexible liquid inlet conduit 401 and flexibility
Eluate conduit 402 may be configured as identical caliber, and liquid metal 9 flows into liquid metal chamber from flexible liquid inlet conduit 401
101, and flow out to heat exchanger components 8 from flexible eluate conduit 402 and cooled down.The connecting pin of probe 1 is installed in flexible stylet
The end of sheathed catheter 4, and flexible liquid inlet conduit 401 and flexible eluate conduit 402 are set in it by flexible stylet conduit 4
On the one hand there is the operation using probe in portion, on the other hand visit convenient for being adjusted by the curvature for controlling flexible stylet conduit 4
The position of needle.
In the above-described embodiments, the liquid metal 9 that heat exchanger components 8 are mainly used for flow out from probe 1 carries out cooling drop
Temperature is simultaneously recycled, and heat exchanger components 8 include arrival end and outlet end, and for flowing in and out for circulating cooling liquid, flexibility goes out liquid
The outlet end of conduit 402 is connected to the arrival end of heat exchanger components 8, and the outlet end of heat exchanger components 8 enters with flexible liquid inlet conduit 401
The connection of mouth end.Finned heat exchanger specifically can be used in heat exchanger components 8 in the present embodiment, and finned heat exchanger is that gas and liquid heat are handed over
The most widely used a kind of heat exchange equipment in parallel operation, it reaches augmentation of heat transfer by installing fin additional on common base tube
Purpose, heat exchange efficiency are high.
In the above-described embodiments, pumping member 7 is used to drive the flowing of liquid metal 9 in entire circulation loop, pump section
Mechanical pump or electromagnetic pump can be used in part 7, is specifically installed in the outlet end in flexible liquid inlet conduit 401 and close to heat exchanger components 8.Liquid
State metal 9 is filled in the circuit being made of flexible liquid inlet conduit 401, probe 1, flexible eluate conduit 402 and heat exchanger components 8
In, and circulated under the driving of pumping member 7, to cool down for probe 1.It is above-mentioned flexible liquid inlet conduit 401, flexible
Eluate conduit 402 and flexible stylet conduit 4 are that flexible material is made, and are conducive to the bending control of probe unit, flexible material
Material includes but is not limited to Thermostable flexible hose.The low melting point being in a liquid state under room temperature gold may be selected in liquid metal 9 in above-described embodiment
Belong to, such as gallium-indium alloy or gallium-indium-tin alloy.Compared with cold brine perfusion radiofrequency catheter, the thermal conductivity of liquid metal 9 is two big
The order of magnitude, big six orders of magnitude of conductivity, more traditional working medium, the probe catheter based on liquid metal can carry out more probe
Effective cooling, and there is no corrosiveness to the head end electrode of probe.It can in addition, having when liquid metal is as radio-frequency antenna
The features such as morphotropism and self-repairing capability, this makes its bent antenna material as function admirable, can readily pass through
Blood vessel enters into the human body, to treat to patient.
In the above-described embodiments, it in order to improve the flexibility of radio frequency heating probe unit, is equipped in flexible stylet conduit 4
Curvature regulating member, it is two sections that flexible stylet conduit 4 is divided to by curvature regulating member, for adjusting flexible stylet conduit 4
Bending degree and bending direction, flexible liquid inlet conduit 401 and flexible eluate conduit 402 inside flexible stylet conduit 4 are soft
Property material, thus also can synchronize realization bending, so as to be probe 1 accurately reaches specifically melt site.
The purpose of the embodiment of the present invention is mainly using liquid metal as the cooling working medium and radio-frequency antenna of probe, both
The heat that probe can be taken away prevents from burning, and can provide radio frequency energy as the antenna of radio frequency generator for probe
Amount, while can also be greatly improved with flexible conduit material buckles, the flexibility of application.
In the above-described embodiments, curvature regulating member specifically includes: more resistance wires 2, and more 2 parallel connections of resistance wire are electrically connected
It connects, and is arranged along the axially spaced-apart of flexible stylet conduit 4, shape memory member 3 is equipped between adjacent two resistance wires 2, quite
It is arranged in resistance wire 1 and 3 alternate intervals of shape memory member.It is equipped on flexible stylet conduit 4 for controlling every resistance wire 2
The regulation button 6 of autonomous working.Specifically, resistance wire 2 can choose nickel-chromium resistance wire, and 2 temperature of resistance wire increases, shape memory
Element 3 is bent, and wire temperature reduces shape memory member 3 and restores to the original state, and is added in this way by controlling different resistance wires 2
Heat can neatly control the bending degree of conduit device, realize the adjustable function of probe catheter camber.Wherein, shape is remembered
Recall element 3 to be made of shape-memory material, specifically usable marmem or shape memory high molecule material.
On the basis of the above embodiments, for the ease of the hand-held of flexible stylet conduit 4, in flexible stylet conduit 4
Probe handle 5 is installed in upper one end far from probe 1, and regulation button 6 is installed in probe handle, and regulation button 6 can visited
It is slided on needle handle 5, and is equipped with the identifier corresponding to different resistance wires 1 in probe handle 5, when adjusting knob 6 slides
When to corresponding resistance wire identifier position, corresponding resistance wire is started to work.Heat-resisting material may be selected in probe handle 5
Production, it is preferable that polytetrafluoroethylene material can be used.
In order to improve cooling efficiency, the liquid metal of low temperature and flexible eluate conduit 402 in flexible liquid inlet conduit 401 are prevented
The liquid metal of interior high temperature influences each other, and is enclosed in the outside of flexible liquid inlet conduit 401 and flexible eluate conduit 402 heat-insulated
Layer 404.The design of thermal insulation layer 404 can prevent the heat exchange of high temperature, low temperature liquid metal in flexible stylet conduit 4, from
And can effectively it cool down for probe 1.
On the basis of the various embodiments described above, miniature webcam 11 and LED light source are also embedded in the transmitting terminal of probe 1
12, miniature webcam 11 is mounted on inside the transmitting terminal of probe 1, with the property of transparent heat-barrier material protection miniature webcam 11
It can be not affected by high temperatures.Compared with the method for positioning probe position outside conventional bulk, on the one hand, this visualization probe can be shown in real time
Show the specific location of probe in vivo；On the other hand, intracorporal tissue blood vessel environment can also be shown by miniature webcam, made
It is more accurate to melt site.
On the basis of the various embodiments described above, with reference to Fig. 6, the radio frequency heating probe unit further include: fan 14, fan
14 outer covers are equipped with radome fairing 15, and for improving the fan thermal effect of fan, fan 14 is oppositely arranged with heat exchanger components 8, to improve
The cooling effect of heat exchanger components 8, and adjusted convenient for the subsequent linkage to probe temperature.
On the basis of the various embodiments described above, with reference to Fig. 4 and Fig. 5, radio frequency heating probe provided by the embodiment of the present invention
Difference in the structure and the various embodiments described above of device is that structure is more miniaturized, the system of pump liquid-state metal with it is micro-fluidic
Technology combine, using micro fluidic device as pumping member 7 come pump liquid-state metal 9, and in this example radio frequency heating spy
The function of release drug is also added into needle device.
Specifically, the probe diameter of probe catheter more tinyization compared with flexible liquid inlet conduit 401 is convenient for large area ablation
Afterwards, the cleaning and ablation of minimal disease.In addition, the transformation that pumping member 7 is also miniaturized, is pumped using micro fluidic device
A small amount of liquid metal 9 is sent, in whole device system, since probe unit is miniaturized, liquid metal 9 is in flexible liquid inlet conduit
401 is also less with the flow of flexible eluate conduit 402, so for the radio frequency heating probe unit after micromation, heat dissipation
Also become to be more easier.
In addition, also adding the function of drug delivery, there are also variations for the structure of corresponding probe catheter.Micro-fluidic
It in device, can include but is not limited to the structures such as Micropump, micro-valve, on the one hand can be the circulation of liquid metal 9 and passing for drug
Offer power is provided, on the other hand can control drug release and burst size.In addition, micro fluidic device is also connected with medicine storing bag 19,
Medicine storing bag 19 can be replaced flexibly, and the size of medicine storing bag 19 and the drug of loading can be selected artificially.Expand probe catheter
Application range in the treatment.Drug delivery hose 403, the outlet of drug delivery hose 403 are additionally provided in probe catheter
End is located at the transmitting terminal of probe 1, and the arrival end of drug delivery hose 403 is connected to micro fluidic device, in micro fluidic device
Under control, drug is flowed into the drug delivery hose 403 in flexible stylet conduit 4 from medicine storing bag 20, is conveyed by drug soft
The outlet end of pipe 403 is flowed out, and then is discharged into specific medicine-feeding part from the transmitting terminal of probe 1.In the present embodiment, Qi Tasuo
There are component and related work principle to carry out detailed and deep explanation in the above embodiments, therefore no longer superfluous
It states.
On the basis of the various embodiments described above, with reference to Fig. 6, the embodiment of the present invention provides a kind of radio frequency ablation device, radio frequency
Ablation apparatus includes the radio frequency heating probe unit in auxiliary electrode 17, radio frequency generator 10 and the various embodiments described above, is penetrated
The generating apparatus 10 that takes place frequently is the device that radio frequency occurs in operative treatment.It is defeated at least provided with two RF energies on radio frequency generator 10
Exit port can drive more radio frequency heating probes when there is multiple RF energy output ports on radio frequency generator 10 simultaneously
Device.Liquid metal 9 in flexible stylet conduit 4 is connect by transmission electric wire with one of RF energy output port, from
And RF energy is output to probe 1 using liquid metal 9；Auxiliary electrode 17 is penetrated by transmission electric wire with therein another
The connection of frequency energy output port, probe 1 and auxiliary electrode 17 form electrode pair, and the rf wave that radio frequency generator 10 issues swashs
Ion in hair tissue shakes, and thermal energy is converted by RF energy, to reach ablation purpose.
On the basis of the above embodiments, data acquisition processing device 13 connects each important portion in radio frequency ablation device
Part, including pumping member 7, radio frequency generator 10, computer 16, fan 14.Computer 16 is acquired as host computer and data
Processing unit electrical connection, controls the operating status of entire radio frequency ablation device.In the transmitting terminal and flexible stylet conduit of probe 1
4 side wall is equipped with multiple temperature sensors 18, and multiple temperature sensors 18 are for real-time monitoring radio frequency heating probe unit
Temperature change.Temperature sensor 18 is electrically connected with data acquisition processing device 13, the probe 1 that temperature sensor 18 detects with
The real time temperature data of flexible stylet conduit 4 are sent on data acquisition processing device 13, are analyzed by the data of computer 16,
Feed back to data acquisition processing device 13 and occurrence frequency and fan to the power of pumping member 7, radio frequency generator 10
14 revolving speed is controlled and is adjusted accordingly.In the present embodiment, can join about the specific structure of radio frequency heating probe unit
According to the content of the various embodiments described above, no longer it is described in detail herein.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of radio frequency heating probe unit characterized by comprising probe, liquid metal, flexible stylet conduit, bending
Spend regulating member, heat exchanger components and pumping member, the connecting pin of the probe is separately connected flexible liquid inlet conduit and soft
Property eluate conduit, the flexible stylet conduit is fixedly connected with the connecting pin of the probe, the flexibility liquid inlet conduit and soft
Property eluate conduit be nested in the flexible stylet catheter interior, the outlet end of the flexibility eluate conduit and the heat exchanger components
Arrival end connection, the outlet end of the heat exchanger components are connected to the arrival end of the flexible liquid inlet conduit, the pumping member dress
Be located in the flexible liquid inlet conduit, the liquid metal under the driving of the pumping member through the flexible liquid inlet conduit,
It is circulated in the circuit of probe, flexible eluate conduit and heat exchanger components composition, the curvature regulating member is embedded at
Curvature in the flexible stylet conduit and for adjusting the flexible stylet conduit.
2. radio frequency heating probe unit according to claim 1, which is characterized in that the curvature regulating member includes:
More resistance wires, the more resistance wire parallel connections are electrically connected and are arranged along the axially spaced-apart of the flexible stylet conduit, adjacent two
Shape memory member is equipped between resistance wire described in root, the flexible stylet conduit is equipped with for controlling every resistance wire independence
The regulation button of work.
3. radio frequency heating probe unit according to claim 2, which is characterized in that the flexible stylet conduit is far from described
One end of probe is equipped with probe handle, and the regulation button is installed in the probe handle.
4. radio frequency heating probe unit according to claim 3, which is characterized in that the feed liquor circulation conduit and liquid follows out
The outside of ring conduit is enclosed with thermal insulation layer.
5. according to claim 1 to the radio frequency heating probe unit any in 4, which is characterized in that the pumping member is
Micro fluidic device is also nested with drug delivery hose, the outlet end position of the drug delivery hose in the flexible stylet conduit
It is connected in the arrival end of the transmitting terminal of the probe, the drug delivery hose with the micro fluidic device, it is described micro-fluidic
Medicine storing bag is also connected on device, the drug in the medicine storing bag conveys under the driving of the micro fluidic device through the drug
It flows out the outlet end of hose.
6. radio frequency heating probe unit according to claim 5, which is characterized in that the liquid metal be gallium-indium alloy or
Gallium-indium-tin alloy.
7. radio frequency heating probe unit according to claim 5, which is characterized in that the transmitting terminal of the probe is equipped with micro-
Type camera and LED light source.
8. according to claim 1 to any radio frequency heating probe unit in 4, which is characterized in that further include: fan, institute
Fan outer cover is stated equipped with radome fairing, the fan is oppositely arranged with the heat exchanger components.
9. a kind of includes the radio frequency ablation device of the radio frequency heating probe unit as described in claim 1 to 8 is any, feature exists
In, comprising: radio frequency heating probe unit, auxiliary electrode and radio frequency generator, the radio frequency generator are equipped with and are used for
Connect the RF energy output port of liquid metal in the auxiliary electrode and the radio frequency heating probe unit.
10. radio frequency ablation device according to claim 9, which is characterized in that further include: data acquisition processing device, institute
The side wall of the transmitting terminal and the flexible stylet conduit of stating probe is equipped with multiple temperature sensors, the pumping member, wind
Fan, radio frequency generator and multiple temperature sensors are electrically connected with the data acquisition processing device, the data acquisition
Power, the radio frequency of processing unit pumping member according to the temperature data feedback regulation of the multiple temperature sensor fill
The revolving speed of the frequency and fan set.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201811061136.8A CN109259856A (en) | 2018-09-12 | 2018-09-12 | Radio frequency heating probe device and radio frequency ablation equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811061136.8A CN109259856A (en) | 2018-09-12 | 2018-09-12 | Radio frequency heating probe device and radio frequency ablation equipment |
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| CN109259856A true CN109259856A (en) | 2019-01-25 |
Family
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| CN201811061136.8A Pending CN109259856A (en) | 2018-09-12 | 2018-09-12 | Radio frequency heating probe device and radio frequency ablation equipment |
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| CN (1) | CN109259856A (en) |
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| CN112891056A (en) * | 2021-01-28 | 2021-06-04 | 云南科威液态金属谷研发有限公司 | Radio frequency thermotherapy system |
| WO2021239028A1 (en) * | 2020-05-27 | 2021-12-02 | 天津美电医疗科技有限公司 | Electric refrigeration-based ablation system employing flexible electric refrigeration probe and flexible electric refrigeration probe |
| CN115429423A (en) * | 2022-11-07 | 2022-12-06 | 海杰亚（北京）医疗器械有限公司 | Waterless microwave ablation needle and microwave ablation system |
| CN117192324A (en) * | 2023-11-07 | 2023-12-08 | 深圳市森美协尔科技有限公司 | Probe detection table |
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