CN109254168A - A kind of sampling needle dual-axis driving device, analyzer and driving method - Google Patents

A kind of sampling needle dual-axis driving device, analyzer and driving method Download PDF

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Publication number
CN109254168A
CN109254168A CN201811314817.0A CN201811314817A CN109254168A CN 109254168 A CN109254168 A CN 109254168A CN 201811314817 A CN201811314817 A CN 201811314817A CN 109254168 A CN109254168 A CN 109254168A
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CN
China
Prior art keywords
axis
sampling needle
mounting plate
drive module
sampling
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Pending
Application number
CN201811314817.0A
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Chinese (zh)
Inventor
皮思
肖辉
闫红力
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Shenzhen Icubio Biotechnology Polytron Technologies Inc
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Shenzhen Icubio Biotechnology Polytron Technologies Inc
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Application filed by Shenzhen Icubio Biotechnology Polytron Technologies Inc filed Critical Shenzhen Icubio Biotechnology Polytron Technologies Inc
Priority to CN201811314817.0A priority Critical patent/CN109254168A/en
Publication of CN109254168A publication Critical patent/CN109254168A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/02Cleaning by the force of jets or sprays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices

Abstract

The invention discloses a kind of sampling needle dual-axis driving device, analyzer and driving method, sampling needle dual-axis driving device, including Y-direction drive module, Z-direction drive module and sampling module;Y-direction drive module includes Y-direction mounting plate (1), Y-direction slide rail (4) and Y-direction synchronous drive mechanism;The first stepper motor (3) for driving Y-direction synchronization mechanism is additionally provided on Y-direction mounting plate;Z-direction drive module is mounted on along the vertical direction on the Y-direction slide rail, and the Y-direction synchronous drive mechanism can drive Z-direction drive module to translate along Y-direction;Sampling module includes the sampling needle (18) in sampling needle fixing seat (5) and installation sampling needle fixing seat;Sampling module is arranged in Z-direction drive module, is driven by the Z-direction synchronization mechanism in Z-direction drive module;The sampling needle dual-axis driving device and analyzer mechanism are compact, and operation is smooth, easy to implement.

Description

A kind of sampling needle dual-axis driving device, analyzer and driving method
Technical field
The present invention relates to a kind of sampling needle dual-axis driving device, analyzer and driving method, particularly suitable for blood cell, In specific protein analysis instrument.
Background technique
Full-automatic blood cell, specific protein analyzer are the important analysis instruments being commonly used in clinical examination, it by pair The analysis of blood or other body fluid measures various biochemical indicators: such as hemoglobin, albumin, total protein, cholesterol, starch Enzyme etc..In conjunction with other clinical datas, comprehensive analysis is carried out, evaluation can be made to organ dysfunction with assisted diagnosis disease, determined modern Benchmark etc. is treated afterwards.
It is full-automatic blood cell, specific protein by the sampled part that " vertical movement+horizontal rectilinear motion " is sampled One of critical component in analyzer, it is responsible for blood sample to be detected, reagent, and cleaning solution is sent into reaction cup by the program of setting In.Current existing sampled part is all by guide supporting seat, two guide rails, and linear bearing or sliding bearing etc. form, this Kind scenario-frame is complicated, and components are more, and parts machining process requires height, requires height, Material Cost height etc. to assembly crewman.
Therefore, it is necessary to design a kind of sampling needle dual-axis driving device, analyzer and driving method.
In addition, sample is extracted from test tube by sampling needle in blood, Biochemical Analyzer, in order to guarantee the accurate of test Property, it needs to clean the surfaces externally and internally of sampling needle, removes remaining sample, and sampling needle device for cleaning just has cleaning Sampling needle inside and outside wall function.Currently, the cleaning device is using more structure: 1, having upper and lower cavities, feed liquor in apparatus main body Pipe is connected with upper lower inner cavity respectively with drain pipe, and structure needs in addition mating cover plate use up and down, material because processing or being opened limitation Higher cost, complex process;2, without accommodating chamber in apparatus main body, cleaning solution is injected cleaning device by inlet tube by syringe, Sampling needle will cause sampling needle outer wall washing not because the direction that cleaning solution injects every time is constant by moving back and forth cleaning outer wall Uniformly, and cleaning solution dosage is very big, higher cost.Therefore, it is necessary to design a kind of sampling needle cleaning device.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of sampling needle dual-axis driving device, analyzer and driving sides Method, the sampling needle dual-axis driving device and analyzer integrated level are high, compact-sized.
The technical solution of invention is as follows:
A kind of sampling needle dual-axis driving device includes Y-direction drive module, Z-direction drive module and sampling module;
Y-direction drive module includes Y-direction mounting plate (1), Y-direction slide rail (4) and Y-direction synchronous drive mechanism;Y-direction sliding is led Rail (4) and Y-direction synchronous drive mechanism are installed on Y-direction mounting plate, and Y-direction synchronous drive mechanism includes Y-direction timing belt (10), Y Axis driving wheel (2) and Y-axis idle pulley (11);Y-direction timing belt is located on Y-axis driving wheel and Y-axis idle pulley;It is also set on Y-direction mounting plate There is the first stepper motor (3) for driving Y-direction synchronization mechanism;
Z-direction drive module is mounted on along the vertical direction on the Y-direction slide rail, the Y-direction synchronous drive mechanism Z-direction drive module can be driven to translate along Y-direction;
Sampling module includes the sampling needle (18) in sampling needle fixing seat (5) and installation sampling needle fixing seat;Sampling module It is arranged in Z-direction drive module, is driven by the Z-direction synchronization mechanism in Z-direction drive module;
Y-direction mounting plate is equipped at least two Y-axis position sensor;
Z-direction drive module is equipped at least one Z axis position sensor, preferably one, is specifically located at Z-direction mounting plate Upper end.
Z-direction drive module includes Z axis fixing seat (21), Z-direction mounting plate (7), Z-direction synchronous drive mechanism and slide-and-guide block (22);
Z axis fixing seat is arranged on Y-direction slide rail, can slide along Y-direction slide rail;
Z-direction mounting plate is fixed in Z axis fixing seat;
Z-direction synchronization mechanism and slide-and-guide block are installed on Z-direction mounting plate;It is additionally provided on Z-direction mounting plate for driving Z To the second stepper motor (6) of synchronization mechanism;
Z-direction synchronization mechanism includes Z axis driving wheel (8), Z axis synchronous belt (14), Z axis driven wheel (15), and Z axis synchronous belt is set Between Z axis driving wheel and Z axis driven wheel.
Z-direction mounting plate is equipped with for the guide edge (24) for sampling needle fixing seat (5) guiding, and guide edge is properly termed as again Z-direction gib block or Z-direction guide plate can actually be a flangings of Z-direction mounting plate.
The Y-axis position sensor is Y-axis optoelectronic switch (13), and Z axis position sensor is Z axis optoelectronic switch (9).
Y-axis optoelectronic switch is 5, and 5 Y-axis optoelectronic switches are arranged in straight line.
The lower end of Z-direction mounting plate is fixed with needle developing room (17);The lower end of sampling needle vertically passes through the needle developing room.
Z-direction mounting plate is equipped with baffle, i.e. optoelectronic switch baffle causes light when baffle blocks the optical path of Y-axis optoelectronic switch The signal intensity of electric switch.Similarly, sampling needle fixing seat is equipped with baffle and causes when baffle blocks the optical path of Z axis optoelectronic switch The signal intensity of optoelectronic switch realizes position detection;
Optoelectronic switch is connected with MCU.
A kind of analyzer, specially protein analyzer, including the sampling needle dual-axis driving device.
Analyzer further includes the sampling needle cleaning device for clear sampling needle;
The sampling needle cleaning device has cleaning and guide function, compact-sized.
Sampling needle cleaning device includes developing room main body (31);
Vertical Channel is equipped in developing room main body;The Vertical Channel includes the upper channel being from top to bottom sequentially communicated (34), feed liquor minor air cell (38), intermediate channel (36), drainage chamber (37) and lower channel (35);
Feed pathway and apocenosis passage are additionally provided in developing room main body;Feed pathway is connected to feed liquor minor air cell;Drain is logical Road is connected to drainage chamber;
The diameter of upper channel, intermediate channel and lower channel is respectively d1, d2 and d3;D1 > d3, and d2 > d3;
The diameter d3 of lower channel is greater than or equal to the outside diameter d 4 of sampling needle, to allow sampling needle to pass through lower channel (in other words Across lower channel), and d3-d4 is less than k, k is preset value;It, can be close by lower channel when k can guarantee that sampling needle is inserted into lower channel Envelope, 0.05~0.1mm of value range of k guarantee the smooth movement of sampling needle energy, while being not in leakage in cleaning solution emptying Phenomenon.The preferred value of k is 0.06,0.07,0.08,0.09.
Liquid inlet joint (32) and draining connector (33) are respectively equipped at the outward opening of feed pathway and apocenosis passage;Feed liquor connects Head and draining connector are respectively used to dock with feed pathway and apocenosis passage, and are respectively used to that cleaning is inputted and be discharged by pipeline Liquid.
Outside is equipped with the liquid pump for being controlled by MCU, for being pumped into cleaning solution and extraction cleaning solution.
It is internal thread interface at the outward opening of feed pathway and apocenosis passage;The liquid inlet joint and draining connector is equal For male connection.Male connection can be described as external screw thread plug again.
Upper channel is identical with the diameter of intermediate channel.
The concentricity of d2 and d3 is less than 0.02mm.
The bottom of feed liquor minor air cell is bowl-type, is used to form vortex, promotes flush efficiency and improves flushing effect.
Feed pathway and apocenosis passage are vertical with the Vertical Channel.
Developing room main body is equipped with clamping mechanism, convenient for developing room main body to be fixed on external equipment (such as mounting plate).
The clamping mechanism is card slot.
A kind of sampling needle Two axle drive method, using sampling needle dual-axis driving device above-mentioned;
Using synchronous tape drive mechanism driving sampling needle in horizontal and vertical movement;It is opened using optoelectronic switch baffle and photoelectricity It closes and realizes position detection.In motion process, it is directly realized cleaning, clever structure.
The utility model has the advantages that
Sampling needle dual-axis driving device, analyzer and driving method of the invention is solid by horizontal frames and upright frame It is fixed, using y-axis stepper motor and Z axis stepper motor, position detection is realized using optoelectronic switch baffle and optoelectronic switch, using same Step band is used as transmission mechanism, runs smoothly;Positioned by optoelectronic switch, mechanical position limitation is protected, have it is compact-sized, Convenient for assembly, and part is easy to process, advantage at low cost.
The present invention is designed by reasonable structure, in the Y-axis direction, allows guiding on Y-direction slide rail and Y-direction mounting plate While to replace traditional guide shaft, to carry out positioning and guiding movement;In the Z-axis direction, the up and down motion of synchronous belt, Z-direction peace are utilized The guide edge of loading board replaces the guide shaft to carry out guide-localization, while sampling needle also has certain lead with the clearance fit of needle developing room To effect.Structure after optimization reduces part, simplifies structure, simplifies production technology and reduces Material Cost, simultaneously Also it is able to satisfy the precision of movement and the stability requirement of movement.
Cleaning solution is directly injected by sampling needle cleaning device using syringe by liquid inlet joint, because cleaning fluid pressure is larger, Vortex (arrow in Fig. 2 is seen in direction) is formed on bowl-type bottom in feed liquor minor air cell (38), and most of cleaning solution is logical along centre Road (36) is flowed downward with eddy currents, and when sampling needle pumps, sampling needle all directions are cleaned liquid and uniformly wrap It wraps up in, when cleaning solution reaches drainage chamber (7), vacuum pump generates negative pressure, will clean waste liquid and taken out from liquid inlet joint by hose It walks.Small part cleaning solution is flowed up along upper channel (34) when feed liquor, when kinetic energy is converted to gravitional force, along upper channel (34) The cleaning solution of flowing gradually decreases, when upper channel (34) length where appropriate, all cleaning solutions flowed up finally in gravity Under the action of can flow downwardly into drainage chamber (37).When drain, because lower channel (35) size d3 and sampling needle outer diameter almost It is identical, sealing function can be played, waste liquid does not flow through lower channel (35) discharge.
In addition, developing room main body can be directly buckled on instrument, convenient for fixing.
Moreover, Vertical Channel has both guide function.
To sum up, this cleaning device clever structure, manufacturing cost is low, economical and practical, easy to process, it is easily assembled, Easy to use, articulation efficiency is high, and clear effect can significantly improve, and is suitble to promotion and implementation.
Therefore, this analyzer has compact-sized, and feature-rich, flexibility is good, feature easy to implement, is suitble to promote Implement.
Detailed description of the invention
Fig. 1 is the general structure schematic diagram (forward direction perspective view) of sampling needle dual-axis driving device;
Fig. 2 is the general structure schematic diagram (side isometric view) of sampling needle dual-axis driving device;
Fig. 3 is the general structure schematic diagram (main view) of sampling needle cleaning device;
Fig. 4 is the schematic diagram of internal structure of sampling needle cleaning device;
Fig. 5 is the general structure schematic diagram (top view) of sampling needle cleaning device;
Fig. 6 is that display screen dims schematic diagram;
Fig. 7 is constant-current charge schematic diagram;
Fig. 8 is electrical equipment current detecting and control relay circuit figure;
Fig. 9 is amplification factor adjustable amplifier schematic diagram;
Label declaration: 1-Y is sampled to mounting plate, 2-Y axis driving wheel, the first stepper motor of 3-, 4-Y to slide rail, 5- Needle fixing seat, 6- second stepper motor, 7-Z is to mounting plate, 8-Z axis driving wheel, 9-Z axis optoelectronic switch, 10-Y to synchronous belt, 11-Y axis idle pulley, 12-Y pivot pin axis, 13-Y axis optoelectronic switch, 14-Z is to synchronous belt, 15-Z axis driven wheel, 16-Z axle suspension arm pin Axis, 17- needle developing room, 18- sampling needle, 19- sampling needle briquetting, 20-Z are slided to optoelectronic switch baffle, 21-Z axis fixing seat, 22- Action-oriented block, 23-Y is to optoelectronic switch baffle.
31- developing room main body, 32- liquid inlet joint, 33- draining connector, 34- upper channel, 35- lower channel, the centre 36- are logical Road, 37- drainage chamber, 38- feed liquor minor air cell, 39- groove.
Specific embodiment
The present invention is described in further details below with reference to the drawings and specific embodiments:
Embodiment 1: such as Fig. 1~2, a kind of sampling needle dual-axis driving device is equipped with Y-direction slide rail on Y-direction mounting plate 1 4,21 one end of Z axis fixing seat is fixed on Y-direction slide rail, and the other end is connected with Y-direction timing belt 10, in the first stepper motor 3 Drive under carry out transverse reciprocating movement, on Y-direction mounting plate 1 folding have a rib, carry out the protection of mechanical limit position.Another On one direction, slide-and-guide block 22 is matched with the guide edge on Y-direction mounting plate 1, under the drive of the first stepper motor, edge Guide edge laterally do gliding motility, play guiding and circumferentially positioned effect.Guiding movement and positioning on the two directions Guide shaft is added to add the motor pattern of linear bearing instead of existing guide shaft fixing seat.Y-axis optoelectronic switch 13 is fixed on Y-direction mounting plate On 1, the accurate positioning of specific position is carried out using optoelectronic switch.
Second stepper motor 6 is housed on Z-direction mounting plate 7, Z axis driving wheel 8 is housed on output shaft.Z axis cantilever pin shaft 16 are fixed on the other end, and Z axis driven wheel 15 is housed thereon.Z axis synchronous belt 14 is around mounted in Z axis driving wheel 8 and Z axis driven wheel 15 On.5 one end of sampling needle fixing seat is directly connected with Z axis synchronous belt 14, and the other end is matched with the guide edge of Z-direction mounting plate 7, Under the drive of motor, move up and down along guide edge.Sampling needle 18 is loaded in sampling needle fixing seat 5, with 17 phase of needle developing room Even, needle developing room 17 is directly anchored on Z-direction mounting plate 7, forms a guiding role.Such structure is instead of traditional Z-direction On add guide shaft to add the motion mode of linear bearing with guide shaft fixing seat, keep structure more terse and compact, stability is strong, and cost is more It is low.
First stepper motor 3 is fixed on one end of Y-direction mounting plate 1, and Y-axis driving wheel 2 is housed on output shaft, uses clamp screw Nail locking.Y-axis pin shaft 12 is fixed on the other end, and Y-axis idle pulley 11 is housed thereon, is locked with holding screw.Y-direction timing belt 10 installs around On Y-axis driving wheel 2 and Y-axis idle pulley 11.Y-direction slide rail 4 is mounted on Y-direction mounting plate 1, is fixed with M3 screw.Z axis is fixed 21 one end of seat are fixed with M3 screw with 4 phase of Y-direction slide rail, and the open slot of the other end sticks into Y-direction timing belt 10, solid with M3 screw It is fixed.Slide-and-guide block 22 is fixed on Z-direction mounting plate 7, and open slot cooperates with the guide edge of Y-direction mounting plate 1.Z-direction mounting plate 7 It is fixed in Z axis fixing seat 21 by M4 screw, with Z axis fixing seat horizontal movement.Second stepper motor 6 is fixed on Z-direction Z axis driving wheel 8 is fixed with holding screw on output shaft in one end of mounting plate 7.Z axis cantilever pin shaft 16 is fixed on the other end, Z axis driven wheel 15 is fixed with holding screw thereon.Simultaneously with M4*16 hexagon socket head cap screw from the M4 screw thread of 7 side of Z-direction mounting plate Across Z axis cantilever pin shaft 16 is held, play tensioning synchronous belt.Z axis synchronous belt 14 is around mounted in Z axis driving wheel 8 and Z axis driven wheel On 15.The slot open at one end of sampling needle fixing seat 5 sticks into Z axis synchronous belt 14, is fixed with M3 screw, and other end open slot is pacified with Z-direction The guide edge of loading board 7 cooperates, and moves up and down under the drive of Z axis synchronous belt 14.Sampling needle 18 is loaded in sampling needle fixing seat 5 On, it is connected with needle developing room 17.
The material of the Y-direction mounting plate is 5052 aluminium sheets of 2.0mm, is bent with guide edge thereon and places Y-direction sliding and leads The platform edges of rail, guide edge straightness are 0.02mm.
The material of the slide-and-guide block is that slide coefficient is small and the plastic cement of high abrasion.
The material of the Z-direction mounting plate is 5052 aluminium sheets of 2.0mm, is bent with guide edge thereon, guide edge straightness is 0.02mm。
The material of the sampling needle fixing seat is that slide coefficient is small and the plastic cement of high abrasion.
Such as Fig. 3~5, a kind of sampling needle cleaning device, including developing room main body 31;
Vertical Channel is equipped in developing room main body;The Vertical Channel includes the upper channel being from top to bottom sequentially communicated 34, feed liquor minor air cell 38, intermediate channel 36, drainage chamber 37 and lower channel 35;
Feed pathway and apocenosis passage are additionally provided in developing room main body;Feed pathway is connected to feed liquor minor air cell;Drain is logical Road is connected to drainage chamber;
The diameter of upper channel, intermediate channel and lower channel is respectively d1, d2 and d3;D1 > d3, and d2 > d3;
The diameter d3 of lower channel is greater than or equal to the outside diameter d 4 of sampling needle, to allow sampling needle to pass through lower channel (in other words Across lower channel), and d4-d3 is less than k, k is preset value;It, can be close by lower channel when k can guarantee that sampling needle is inserted into lower channel Envelope.
Liquid inlet joint 32 and draining connector 33 are respectively equipped at the outward opening of feed pathway and apocenosis passage;Liquid inlet joint and Draining connector is respectively used to dock with feed pathway and apocenosis passage, and is respectively used to that cleaning solution is inputted and be discharged by pipeline Body.Outside is equipped with the liquid pump for being controlled by MCU, for being pumped into cleaning solution and extraction cleaning solution.
It is internal thread interface at the outward opening of feed pathway and apocenosis passage;The liquid inlet joint and draining connector is equal For male connection.Male connection can be described as external screw thread plug again.
Upper channel is identical with the diameter of intermediate channel.
The concentricity of d2 and d3 is less than 0.02mm.
The bottom of feed liquor minor air cell is bowl-type, is used to form vortex, promotes flush efficiency and improves flushing effect.
Feed pathway and apocenosis passage are vertical with the Vertical Channel.
Developing room main body is equipped with clamping mechanism, convenient for developing room main body to be fixed on external equipment (such as mounting plate).
The clamping mechanism is card slot.
Liquid inlet joint and draining connector are fixed in developing room main body by smearing a small amount of screw thread glue.
The diameter of upper channel and intermediate channel is respectively d1 and d2, and the diameter of lower channel is d3, and requires d1 and d2 big It is slightly larger than the outer diameter of cleaned sampling needle in d3, d3.D1 size is connected through entire feed liquor minor air cell and with drainage chamber top, d2 Size is communicated with drainage chamber, and d2 and d3 need to guarantee 0.02 concentricity.
Feed liquor minor air cell 38 is characterized in that bottom shape is bowl-type, and drainage chamber 37 without specific requirement only needs that liquid can be accommodated Body.
Developing room main body includes retaining structure, and retaining structure is groove (such as dovetail groove), and the depth of groove can be according to tool Depending on mounting structure.
In addition, (one) such as Fig. 6, which also has the brightness regulation electricity for control panel display screen light emission luminance Road;The brightness regulating circuit includes MCU, LED light string, triode, potentiometer Rx and A/D converter;Triode is NPN type Triode;The fixed frame Shanghai of display screen is equipped with rotary switch and is coaxially connected with potentiometer Rx;
Potentiometer Rx and first resistor R1 concatenates to form partial pressure branch, and partial pressure branch one terminates positive pole Vcc, partial pressure branch The other end on road is grounded;The tie point of potentiometer Rx and first resistor R1 connect the input terminal of A/D converter;A/D converter it is defeated The data-in port of MCU is terminated out;
LED light string includes the LED light of multiple concatenations;The anode of LED light string meets positive pole Vcc;The cathode of LED light string connects The pole E of the pole C of triode, triode is grounded through second resistance R2;The output end for meeting MCU of the pole B of triode.Positive pole Vcc is 5V, and A/D converter is 8 Bits Serial output type converters.
(2) such as Fig. 7, it includes constant pressure driving for the constant-current charging circuit that lithium battery charges that analyzer, which uses lithium battery power supply, Chip and current feedback circuit;
(1) voltage output end of constant pressure driving chip is the positive output end VOUT+ of constant-current charging circuit;Constant pressure driving chip Negative output terminal ground connection;
Constant pressure driving chip is powered by DC-voltage supply end VIN+ and VIN-;
(2) current feedback circuit described in includes resistance R1, R2 and R5 and reference voltage end VREF+;
Reference voltage end VREF+ passes through resistance R1, R2 and R5 ground connection being sequentially connected in series;
The tie point of resistance R5 and R2 are the negative output terminal VOUT- of constant-current charging circuit;
The tie point of resistance R1 and R2 meet the feedback end FB of constant pressure driving chip.
Constant-current charging circuit further includes voltage feedback circuit;
Voltage feedback circuit includes resistance R3 and R4 and diode D1;
Resistance R3 and R4 series connection are followed by between the positive output end VOUT+ and ground of constant-current charging circuit;Resistance R3's and R4 Tie point connects the anode of diode D1;The cathode of diode D1 meets the feedback end FB of constant pressure driving chip.
(3), such as Fig. 8-9, the device current that analyzer also has detects and control relay circuit (also referred to as over-current detection And protection circuit) be described as follows:
Working principle: mutual by generating, current transformer in live alternating current wires insertion current transformer (or coil) Inducing current, live electric power is bigger, and mutual inducing current is also bigger, and live electric power is smaller, and mutual inducing current is also just smaller, because This utilizes voltage comparator, as soon as a signal waveform can be exported, master controller (MCU) can be showed by included AD acquisition The size of current information of field, to reach detection effect.It is by four rectifier diodes that AC mutual induction is electric in circuit design Circulation changes DC current into, output signal then there are two types of, one kind is analog quantity, is exported by VOUT, is output to MCU;There are also one kind For TTL low and high level, relay is directly controlled for being switched off and on the power supply of main power source.
Circuit description:
The output signal of current transformer obtains Vin through bridge rectifier;Comparator compares Vin and reference voltage Vref, If Vin > Vref, comparator exports low level, and control relay disconnects.
In addition, Vin is amplified into the port ADC of MCU through amplifier (i.e. with the port of A/D conversion function);
Since signal may be more faint, devise the amplifier of adjustable amplification factor;Physical circuit connection and work It is as follows to make principle:
The output end Vin of bridge rectifier is signal end, and the signal end meets operational amplifier LM393 through resistance R0's Inverting input terminal, the noninverting input of operational amplifier LM393 is grounded through resistance R0, and operational amplifier LM393's is in the same direction defeated Enter end and also connect 44 input channels for selecting a selector through 4 resistance R01-R04 respectively, 4 select the output channel of a selector to connect The output end vo ut, Vout of operational amplifier LM393 connects the end ADC of MCU;
In addition 2 output ports of MCU connect 4 respectively the channel of a selector are selected to select end A and B;
The calculation formula of Vout and Vin:
Vout=Vin* (Rx+R0)/R0;Wherein, Rx=R01, R02, R03 or R04;Selection is determined based on gated end AB Which resistance;And R01, R02, R03 and R04 are different;Preferred R04=5*R03=25*R02=100*R01;R01= 5*R0. realizes range and precision switching in which can be convenient.

Claims (10)

1. a kind of sampling needle dual-axis driving device, which is characterized in that including Y-direction drive module, Z-direction drive module and sampling mould Block;
Y-direction drive module includes Y-direction mounting plate (1), Y-direction slide rail (4) and Y-direction synchronous drive mechanism;Y-direction slide rail (4) it is installed on Y-direction mounting plate with Y-direction synchronous drive mechanism, Y-direction synchronous drive mechanism includes Y-direction timing belt (10), Y-axis Driving wheel (2) and Y-axis idle pulley (11);Y-direction timing belt is located on Y-axis driving wheel and Y-axis idle pulley;It is additionally provided on Y-direction mounting plate For driving the first stepper motor (3) of Y-direction synchronization mechanism;
Z-direction drive module is mounted on along the vertical direction on the Y-direction slide rail, and the Y-direction synchronous drive mechanism can drive Dynamic Z-direction drive module is translated along Y-direction;
Sampling module includes the sampling needle (18) in sampling needle fixing seat (5) and installation sampling needle fixing seat;Sampling module setting In Z-direction drive module, driven by the Z-direction synchronization mechanism in Z-direction drive module;
Y-direction mounting plate is equipped at least two Y-axis position sensor;
Z-direction drive module is equipped at least one Z axis position sensor.
2. according to sending out sampling needle dual-axis driving device described in claim 1, which is characterized in that Z-direction drive module includes that Z axis is solid Reservation (21), Z-direction mounting plate (7), Z-direction synchronous drive mechanism and slide-and-guide block (22);
Z axis fixing seat is arranged on Y-direction slide rail, can slide along Y-direction slide rail;
Z-direction mounting plate is fixed in Z axis fixing seat;
Z-direction synchronization mechanism and slide-and-guide block are installed on Z-direction mounting plate;It is additionally provided on Z-direction mounting plate for driving Z-direction same Walk the second stepper motor (6) of mechanism;
Z-direction synchronization mechanism includes Z axis driving wheel (8), Z axis synchronous belt (14), Z axis driven wheel (15), and Z axis synchronous belt is located at Z Between axis driving wheel and Z axis driven wheel.
3. according to sending out sampling needle dual-axis driving device as claimed in claim 2, which is characterized in that Z-direction mounting plate is equipped with and is used for For the guide edge (24) of sampling needle fixing seat (5) guiding.
4. according to sending out sampling needle dual-axis driving device described in claim 1, which is characterized in that the Y-axis position sensor For Y-axis optoelectronic switch (13), Z axis position sensor is Z axis optoelectronic switch (9).
5. according to sending out sampling needle dual-axis driving device described in claim 1, which is characterized in that Y-axis optoelectronic switch is 5,5 Y-axis optoelectronic switch is arranged in straight line.
6. according to sending out sampling needle dual-axis driving device as claimed in claim 2, which is characterized in that the lower end of Z-direction mounting plate is fixed There are needle developing room (17);The lower end of sampling needle vertically passes through the needle developing room.
7. a kind of analyzer, which is characterized in that including sampling needle dual-axis driving device described in any one of claims 1-6.
8. analyzer according to claim 7, which is characterized in that further include the sampling needle cleaning dress for clear sampling needle It sets;
Sampling needle cleaning device includes developing room main body (31);
Vertical Channel is equipped in developing room main body;The Vertical Channel includes the upper channel being from top to bottom sequentially communicated (34), feed liquor minor air cell (38), intermediate channel (36), drainage chamber (37) and lower channel (35);
Feed pathway and apocenosis passage are additionally provided in developing room main body;Feed pathway is connected to feed liquor minor air cell;Apocenosis passage with Drainage chamber connection;
The diameter of upper channel, intermediate channel and lower channel is respectively d1, d2 and d3;D1 > d3, and d2 > d3;
The diameter d3 of lower channel is greater than or equal to the outside diameter d 4 of sampling needle, and to allow sampling needle by lower channel, and d4-d3 is less than K, k are preset value;When k can guarantee that sampling needle is inserted into lower channel, lower channel can be sealed.
9. analyzer according to claim 8, which is characterized in that set respectively at the outward opening of feed pathway and apocenosis passage There are liquid inlet joint (32) and draining connector (33);Liquid inlet joint and draining connector are respectively used to and feed pathway and apocenosis passage pair It connects, and is respectively used to that cleaning liquid is inputted and be discharged by pipeline.
10. a kind of sampling needle Two axle drive method, which is characterized in that double using sampling needle described in any one of claims 1-6 Axial brake device;
Using synchronous tape drive mechanism driving sampling needle in horizontal and vertical movement;It is real using optoelectronic switch baffle and optoelectronic switch Existing position detection.
CN201811314817.0A 2018-11-06 2018-11-06 A kind of sampling needle dual-axis driving device, analyzer and driving method Pending CN109254168A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110161257A (en) * 2019-06-18 2019-08-23 广东优尼德生物科技有限公司 A kind of glycolated hemoglobin analysis

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104374935A (en) * 2014-10-28 2015-02-25 利多(香港)有限公司 Sampling device of fully automatic biochemical analyzer
CN104374933A (en) * 2014-10-28 2015-02-25 利多(香港)有限公司 Fully automatic biochemical analyzer
CN205484385U (en) * 2016-01-15 2016-08-17 深圳市帝迈生物技术有限公司 Autoinjection blood analyzer and pjncture needle positioner thereof
CN205496146U (en) * 2016-03-31 2016-08-24 深圳迈瑞生物医疗电子股份有限公司 Sample analytical equipment and sampling needle belt cleaning device
CN108177839A (en) * 2018-01-10 2018-06-19 长沙修恒信息科技有限公司 A kind of reaction tube label printing, transmission and affixing system
CN209028088U (en) * 2018-11-06 2019-06-25 深圳市库贝尔生物科技股份有限公司 A kind of sampling needle dual-axis driving device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104374935A (en) * 2014-10-28 2015-02-25 利多(香港)有限公司 Sampling device of fully automatic biochemical analyzer
CN104374933A (en) * 2014-10-28 2015-02-25 利多(香港)有限公司 Fully automatic biochemical analyzer
CN205484385U (en) * 2016-01-15 2016-08-17 深圳市帝迈生物技术有限公司 Autoinjection blood analyzer and pjncture needle positioner thereof
CN205496146U (en) * 2016-03-31 2016-08-24 深圳迈瑞生物医疗电子股份有限公司 Sample analytical equipment and sampling needle belt cleaning device
CN108177839A (en) * 2018-01-10 2018-06-19 长沙修恒信息科技有限公司 A kind of reaction tube label printing, transmission and affixing system
CN209028088U (en) * 2018-11-06 2019-06-25 深圳市库贝尔生物科技股份有限公司 A kind of sampling needle dual-axis driving device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110161257A (en) * 2019-06-18 2019-08-23 广东优尼德生物科技有限公司 A kind of glycolated hemoglobin analysis

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