CN109248715A - Anion exchange resin and its preparation method and application - Google Patents
Anion exchange resin and its preparation method and application Download PDFInfo
- Publication number
- CN109248715A CN109248715A CN201811123064.5A CN201811123064A CN109248715A CN 109248715 A CN109248715 A CN 109248715A CN 201811123064 A CN201811123064 A CN 201811123064A CN 109248715 A CN109248715 A CN 109248715A
- Authority
- CN
- China
- Prior art keywords
- polymer
- exchange resin
- anion exchange
- microballoon
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/08—Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/12—Macromolecular compounds
- B01J41/13—Macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The invention discloses anion exchange resin and its preparation method and application.Wherein, the method for preparing anion exchange resin includes: that (1) will be mixed by the polymer microballoon of sulfonation processing with amine polymer, obtains the polymer microballoon for being adsorbed with the amine polymer；(2) polymer microballoon for being adsorbed with amine polymer is mixed with epoxide, obtains the anion exchange resin.The method and step for preparing anion exchange resin is simple, synthesis cycle is short, is suitable for large-scale volume production, and stable product quality is controllable.
Description
Technical field
The present invention relates to analytical chemistry fields, specifically, the present invention relates to the method, the yin that prepare anion exchange resin
The purposes of ion exchange resin and the anion exchange resin.
Background technique
Ion chromatography (Ion Chromatography, IC) is one kind of high performance liquid chromatography (HPLC), is analysis ion
A kind of liquid chromatography.Ion chromatography method be by the solute molecule of electrification with it is tradable in ion exchange stationary phase
The method that ion swapped and reached separation purpose.This method relies primarily on the interaction between charge, utilizes charged molecule
The fine difference of middle charge and separated, separation capacity with higher, its essence is analysis sample in ion, ion hand over
Change the connection between functional group and mobile phase three.Ion chromatographic column is the key that in ion chromatography.Traditional chromatography
Column preparation process is cumbersome, and method is complicated, largely uses reagent and high labor cost, the separation property of the chromatographic column filler of different batches
Energy difference is big, and repeatability is bad.
Chinese patent CN107497138A discloses a kind of semi-automatic synthetic method of online synthetic filling in chromatographic column,
It is raw materials used to generate linear polymer for butanediol diglycidyl ether and methylamine reaction, after Electrostatic Absorption to sulfonation
The surface PS/DVB, the molecular weight of polymer is not easy to control during being somebody's turn to do, it is difficult in microsphere surface uniform adsorption, lead to analytic process
Middle chromatography peak type broadens, and influences separating degree and column effect, and online synthesis is difficult to scale volume production.
Thus, the existing means for preparing ion chromatographic column filler still have much room for improvement.
Summary of the invention
The present invention is directed to solve at least some of the technical problems in related technologies.For this purpose, of the invention
One purpose is that proposition prepares the method for anion exchange resin, the use of anion exchange resin and the anion exchange resin
On the way.The method and step for preparing anion exchange resin is simple, synthesis cycle is short, is suitable for large-scale volume production, and product matter
It measures stably and controllable.
In one aspect of the invention, the invention proposes a kind of methods for preparing anion exchange resin.According to this hair
Bright embodiment is adsorbed this method comprises: (1) mixes the polymer microballoon handled by sulfonation with amine polymer
There is the polymer microballoon of the amine polymer；(2) by the polymer microballoon and epoxy compound for being adsorbed with amine polymer
Object mixing, obtains the anion exchange resin.This method is made using the polymer microballoon after sulfonation as skeleton by electrostatic interaction
Amine polymer is adsorbed on polymer microballoon surface, and microsphere surface is made to contain free amine groups.And then utilize epoxy compound
Amine at different levels in amine polymer are completely converted into quaternary amine by object, to make the polymer microballoon for being adsorbed with amine polymer to yin
Ion has retention, completes the preparation of anion exchange resin.This method is few without complex chemical reaction, reaction step, letter
It is single easy, and resin exchange capacity is controllable, is suitable for scale of mass production.
In addition, the method according to the above embodiment of the present invention for preparing anion exchange resin can also have following add
Technical characteristic:
In some embodiments of the invention, the polymer microballoon is polystyrene-divinyl benzene copolymer (PS/
DVB) microballoon or vinyl xylene, ethyl vinyl benzene-divinyl benzene copolymer microballoon.
In some embodiments of the invention, the partial size of the polymer microballoon is 3~20 μm, and the degree of cross linking is 1~90%,
The polymer microballoon is non-porous or aperture is
In some embodiments of the invention, the amine polymer is the polyethylene of polyethyleneimine or ethylenediamine end-blocking
Imines.The molecular weight of amine polymer is fixed as a result, it is easier to be adsorbed on polymer microballoon surface, the anion being prepared
Exchanger resin quality is more stable.
In some embodiments of the invention, the molecular weight of the amine polymer is 600~7000.
In some embodiments of the invention, the epoxide is selected from methyloxetane, epoxychloropropane, epoxy
At least one of vinylbenzene, glycidol and glycidyl propargyl ether.It is poly- that raising amine can be further conducive to as a result,
It closes amine at different levels in object and is converted into quaternary amine, to further increase the exchange capacity of anion exchange resin.
In some embodiments of the invention, in step (1), the time that the mixing carries out is 20~120min.As a result,
It can further improve adsorbance of the amine polymer on polymer microballoon.
In some embodiments of the invention, in step (2), described be blended under 50~90 degrees Celsius is carried out, progress
Time is 20~60min.Amine at different levels in amine polymer can be further conducive to as a result, and be converted into quaternary amine.
In another aspect of this invention, the invention proposes a kind of anion exchange resin.According to an embodiment of the invention,
The anion exchange resin is prepared by the method for preparing anion exchange resin of above-described embodiment.The yin as a result,
The preparation method of ion exchange resin is simple, and exchange capacity is stably and controllable, is suitable for scale of mass production.
In another aspect of the invention, the invention proposes the anion exchange resin of above-described embodiment as ion chromatography
Purposes of the column packing in Ion Chromatographic Method.By using the anion exchange resin of above-described embodiment as ion color
Column packing is composed, can further improve the separating property of ion chromatographic column.
Additional aspect and advantage of the invention will be set forth in part in the description, and will partially become from the following description
Obviously, or practice through the invention is recognized.
Detailed description of the invention
Above-mentioned and/or additional aspect of the invention and advantage will become from the description of the embodiment in conjunction with the following figures
Obviously and it is readily appreciated that, in which:
Fig. 1 is the electromicroscopic photograph for the anion exchange resin being prepared in embodiment 1；
Fig. 2 be the anion exchange resin that is prepared using embodiment 1 as filler ion chromatographic column to 7 kinds of yin from
The chromatogram that son is separated.
Specific embodiment
The embodiment of the present invention is described below in detail.The embodiments described below is exemplary, and is only used for explaining this hair
It is bright, and be not considered as limiting the invention.Particular technique or condition are not specified in embodiment, according to text in the art
It offers described technology or conditions or is carried out according to product description.Reagents or instruments used without specified manufacturer,
For can be with conventional products that are commercially available.
In one aspect of the invention, the invention proposes a kind of methods for preparing anion exchange resin.According to this hair
Bright embodiment is adsorbed this method comprises: (1) mixes the polymer microballoon handled by sulfonation with amine polymer
There is the polymer microballoon of amine polymer；(2) polymer microballoon for being adsorbed with amine polymer is mixed with epoxide, is obtained
To anion exchange resin.This method inhales amine polymer using the polymer microballoon after sulfonation as skeleton, by electrostatic interaction
It is attached to polymer microballoon surface, microsphere surface is made to contain free amine groups.And then amine is polymerize using epoxide
Amine at different levels in object are completely converted into quaternary amine, retain so that the polymer microballoon for being adsorbed with amine polymer be made to have anion
Effect completes the preparation of anion exchange resin.This method is few without complex chemical reaction, reaction step, simple and easy, and resin
Exchange capacity is controllable, is suitable for scale of mass production.
According to an embodiment of the invention, above-mentioned sulfonation processing concrete operations condition is not particularly restricted, it can be using this
The conventional method that sulfonation is carried out to polymer microballoon in field.Specific example according to the present invention, sulfonation are handled according to following step
It is rapid to carry out: by polymer microballoon with 80~98% concentrated sulfuric acids according to solid-to-liquid ratio 1g:(5~20) mL mixes, and reaction temperature, which is arranged, is
60~100 DEG C, react 0.5~12h, cool down after reaction, sulfonation post-consumer polymer microballoon is cleaned it is colourless to waste liquid, dry it is standby
With.Inventor has found in an experiment, by carrying out sulfonation to polymer microballoon, can significantly improve the reactivity of polymer microballoon
Can, and above-mentioned sulfonation treatment conditions are also that inventor optimizes and obtains by a large amount of experiment, are carried out except above-mentioned condition
Operation, may largely effect on the reactivity worth of polymer microballoon.For example, the solid-to-liquid ratio of polymer microballoon is too low to will lead to sulfonation
Degree not enough, reduces filler exchange capacity；Reaction temperature is excessively high, will lead to microballoon rupture, fragment is generated, to reduce filled column
Effect；Reaction time is too long, will lead to that sulfonation is excessive, influences the reservation of object.
According to an embodiment of the invention, being used to prepare the type of the polymer microballoon of anion exchange resin not by special
Limitation, as long as can sulfonation polymer microballoon, those skilled in the art can select according to actual needs.According to
Specific embodiments of the present invention, polymer microballoon can be polystyrene-divinyl benzene copolymer (PS/DVB) microballoon or second
Base vinyl benzene-divinyl benzene copolymer microballoon.Other common polymer microballoons relative to this field, PS/DVB microballoon and
Vinyl xylene, ethyl vinyl benzene-divinyl benzene copolymer microballoon source is more extensive, and cost of material is lower, and both microballoons are mechanical
Intensity is high, is suitble to higher filling pressure, to improve chromatographic column column effect；In addition, such polymer microballoon is to organic solvent
Tolerance is high, and reproducibility is strong, to extend service life indirectly.According to an embodiment of the invention, polymer microballoon
Partial size can be 3~20 μm, and the degree of cross linking can be 1~90%, and polymer microballoon can be for non-porous or aperture
Inventors have found that polymer microballoon can both use non-porous microspheres, can also be existed using apertureMicroballoon.It is non-porous
Microballoon exchange capacity is low, is suitble to quickly analysis；Porous microsphere exchange capacity is high, is suitble to the trace inspection of object in complex matrices
It surveys；Aperture is the bigger the better in principle, but the excessive reduction microballoon mechanical strength in aperture, causes to generate fragment during dress column, drop
Low column effect.Absorption of the amine polymer on polymer microballoon can be further conducive to as a result, improve the anion being prepared
The exchange capacity of exchanger resin.
According to an embodiment of the invention, the type of above-mentioned amine polymer is not particularly restricted, only containing number enough
The free amine groups for being used to be subsequently formed quaternary amine of amount.According to a particular embodiment of the invention, amine polymer can be with
Using polyethyleneimine or the polyethyleneimine of ethylenediamine end-blocking, wherein polyethyleneimine both can be sub- using linear polyethylene
Amine can also use nonlinear netted polyethyleneimine, it is preferred to use netted polyethyleneimine, the polyethyleneimine of reticular structure
Amine can more uniformly be adsorbed on polymer microballoon surface, possess more reaction bonded sites, can make the yin being prepared
Ion exchange resin exchange capacity greatly increases.
According to an embodiment of the invention, the molecular weight of above-mentioned amine polymer is 600~7000.Amine polymer as a result,
Molecular weight be suitable for and fixed, it is easier in polymer microballoon surface uniform adsorption, to guarantee that the anion being prepared is handed over
Resin is changed as ion chromatographic column filler in use, chromatographic column has the performances such as good separating degree and column effect.Molecular weight is too low
Amine polymer Effective quantum number is few in aqueous solution, weak with sulfonic group binding force, subsequent reactions site is insufficient, leads to filler
Separating degree is poor；And molecular weight it is excessively high amine substance quality it is excessive, it is difficult to be adsorbed on microsphere surface, be easy to fall off, cause subsequent
Reaction is difficult to carry out.
According to an embodiment of the invention, the type for the epoxide that amine groups react of dissociating with amine polymer
It is not particularly restricted, those skilled in the art can select according to actual needs.According to a particular embodiment of the invention,
Epoxide can be for selected from methyloxetane, epoxychloropropane, Styryl oxide, glycidol and glycidyl alkynes
At least one of propyl ether.It can further be conducive to improve amine at different levels in amine polymer as a result, and be converted into quaternary amine, thus into
The exchange capacity of one step raising anion exchange resin.
According to an embodiment of the invention, the mixing of sulfonation post-consumer polymer microballoon and amine polymer carries out in step (1)
Time can be 20~120min.It can further improve adsorbance of the amine polymer on polymer microballoon as a result,.According to
Specific example of the invention, can be by being added the amine polymer water that concentration is 1~80% for the polymer microballoon after sulfonation
In solution, 20~120min is stirred, to be adsorbed on amine polymer on polymer microballoon.If the amine polymer used
Concentration is too low or mixing time is too short, then not can guarantee effective absorption of the amine polymer on polymer microballoon, and then lead
Polymer microballoon is caused to decline as the performance of chromatographic column filler；If the amine polymer excessive concentration used will lead to material
Waste, mixing time is too long to will lead to whole synthesis technology extended time consumption, this is in the actual production process and undesirable.According to this
The embodiment of invention, in step (2), the polymer microballoon and reacting for epoxide for being adsorbed with amine polymer can be 50
It is carried out at~90 DEG C, the time of progress can be 20~60min.Amine at different levels in amine polymer can be further conducive to as a result,
It is converted into quaternary amine.Inventor has found that reaction temperature is too low or the reaction time is too short, and epoxide can not fill by many experiments
Divide ground to convert quaternary amine for the amine at different levels in amine polymer, causes the exchange capacity of product too low, influence column performance.Such as
Fruit reaction temperature is excessively high or the reaction time is too long, then may cause the oxidation of functional group and go bad, cause chromatographic column selective
It is deteriorated, separating degree reduces.Specific example according to the present invention, can by will be adsorbed with the polymer microballoon of amine polymer with
The epoxide aqueous solution that concentration is 1~30% mixes, and 20~60min is reacted at a temperature of 50~90 DEG C, utilizes epoxidation
The epoxy group closed in object is reacted with the largely free amine groups of microsphere surface, is translated into quaternary amines.
In summary, the method according to an embodiment of the present invention for preparing anion exchange resin, with the polymer after sulfonation
Microballoon is skeleton, so that amine polymer is adsorbed on polymer microballoon surface by electrostatic interaction, contains microsphere surface free
Amine groups.And then the amine at different levels in amine polymer are completely converted into quaternary amine using epoxide, to make to be adsorbed with
The polymer microballoon of amine polymer has retention to anion, completes the preparation of anion exchange resin.This method without
Complex chemical reaction, reaction step are few, simple and easy, and resin exchange capacity is controllable, are suitable for scale of mass production.
In another aspect of this invention, the invention proposes a kind of anion exchange resin.According to an embodiment of the invention,
The anion exchange resin is prepared by the method for preparing anion exchange resin of above-described embodiment.The yin as a result,
The preparation method of ion exchange resin is simple, and exchange capacity is stably and controllable, is suitable for scale of mass production.
It should be noted that equally suitable described previously for feature and advantage described in the method for anion exchange resin are prepared
For above-mentioned anion exchange resin, this is no longer going to repeat them.
In another aspect of the invention, the invention proposes the anion exchange resin of above-described embodiment as ion chromatography
Purposes of the column packing in Ion Chromatographic Method.By using the anion exchange resin of above-described embodiment as ion color
Column packing is composed, can further improve the separating property of ion chromatographic column.
Specific example according to the present invention, in the method that the anion exchange resin prepares ion chromatographic column as filler
In, dress column pressure can be 20~60MPa, and the dress column time can be 0.5~3h.
It should be noted that described previously for preparing described in the method for anion exchange resin, anion exchange resin
Feature and advantage are equally applicable to purposes of the above-mentioned anion exchange resin in Ion Chromatographic Method, herein no longer one by one
It repeats.
Below with reference to specific embodiment, present invention is described, it should be noted that these embodiments are only to describe
Property, without limiting the invention in any way.
Embodiment 1
Reagent: 10% polyethylenimine solution, 10% glycidol, from Shanghai Aladdin reagent purchase；PS/DVB is micro-
Ball, 8 μm of partial size, the degree of cross linking 55%, apertureBeneficial microballoon purchase is known from Wuxi；98% concentrated sulfuric acid, the purchase of Shanghai traditional Chinese medicines.Institute
Being not higher than with ultrapure water conductivity is 18.2M Ω, and reagent is that analysis is pure.
Instrument and equipment: three-necked flask, sand core funnel and its mating pumping and filtering device, mechanical agitator, 6100 ion of Anhui instrument
Chromatograph, packing column machine one.
Anion exchange resin is prepared according to the following steps:
1. weigh 8 μm of partial sizes of 3.4g, 55% degree of cross linking,The PS/DVB polymer microballoon in aperture is put into three mouthfuls of burnings
In bottle, measure 98% concentrated sulfuric acid of 34mL and be slowly added to, be arranged 90 DEG C of reaction temperature, react 1h under mechanical stirring, after it is cold
But, cleaning is colourless to waste liquid, is dried for standby.
2. the microballoon after above-mentioned sulfonation is placed in three-necked flask, the polyethyleneimine of 50mL 10% is added under stirring condition
Amine aqueous solution, adsorption reaction 1h at room temperature, after filtered and clean with a large amount of ultrapure waters.
3. continuing for filler to be put into three-necked flask, the glycidol aqueous solution that 50mL concentration is 10% is added, at 60 DEG C
Lower reaction 1h, after filter cleaning, and dry stand-by, obtain anion exchange resin, electromicroscopic photograph is as shown in Figure 1.
Embodiment 2
Performance of anion-exchange resin test
The anion exchange resin 3g being prepared in embodiment 1 is weighed, is placed in beaker, water 50mL, stirring ultrasound are added
5min pours into packing column machine homogenate tank and connects the void column pipe of 4.6*250mm, column 90min is filled under 50MPa pressure, after
It unloads chromatographic column and encapsulates.It is placed in ion chromatograph and tests separating property.
Test condition:
Test sample: 7 kinds of Common Anions (fluorine ion, chloride ion, sulfate ion, nitrite ion, bromide ion,
Nitrate ion, phosphate anion)；
Flow velocity: 1mL/min；
Eluent concentration: KOH 34mM；
Column temperature: 40 DEG C；
Chi Wen: 40 DEG C；
Inhibit electric current: 150mA；
Sample volume: 20 μ L
According to above-mentioned test condition, the chromatographic fractionation figure of common 7 kinds of anion is obtained, as shown in Figure 2, the results showed that, this
The anion exchange resin of invention as filler be prepared ion chromatographic column can to 7 kinds of Common Anions (fluorine ion, chlorine from
Son, sulfate ion, nitrite ion, bromide ion, nitrate ion, phosphate anion) realize separation well, separating degree
Properly, it trails smaller, the separation to this 7 kinds of anion can be realized in 10min or so, and accuracy is high.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not
It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office
It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field
Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples
It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, modifies, replacement and variant.
Claims (10)
1. a kind of method for preparing anion exchange resin characterized by comprising
(1) it will be mixed by the polymer microballoon of sulfonation processing with amine polymer, obtain being adsorbed with the amine polymer
Polymer microballoon；
(2) polymer microballoon for being adsorbed with amine polymer is mixed with epoxide, obtains the anion exchange
Resin.
2. the method according to claim 1, wherein the polymer microballoon is polystyrene-divinylbenzene
Copolymer microsphere or vinyl xylene, ethyl vinyl benzene-divinyl benzene copolymer microballoon.
3. according to the method described in claim 2, it is characterized in that, the partial size of the polymer microballoon be 3~20 μm, the degree of cross linking
It is 1~90%, the polymer microballoon is non-porous or aperture is 1~3000 angstrom.
4. the method according to claim 1, wherein the amine polymer is that polyethyleneimine or ethylenediamine seal
The polyethyleneimine at end.
5. according to the method described in claim 4, it is characterized in that, the molecular weight of the amine polymer is 600~7000.
6. the method according to claim 1, wherein the epoxide is selected from methyloxetane, epoxy
At least one of chloropropane, Styryl oxide, glycidol and glycidyl propargyl ether.
7. the method according to claim 1, wherein in step (1), the time that the mixing carries out is 20~
120min。
8. the method according to claim 1, wherein in step (2), it is described be blended under 50~90 degrees Celsius into
Row, the time of progress are 20~60min.
9. a kind of anion exchange resin, which is characterized in that the anion exchange resin is by any one of claim 1~8
What the method was prepared.
10. anion exchange resin as claimed in claim 9 is as ion chromatographic column filler in Ion Chromatographic Method
Purposes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811123064.5A CN109248715A (en) | 2018-09-26 | 2018-09-26 | Anion exchange resin and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811123064.5A CN109248715A (en) | 2018-09-26 | 2018-09-26 | Anion exchange resin and its preparation method and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109248715A true CN109248715A (en) | 2019-01-22 |
Family
ID=65048650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811123064.5A Pending CN109248715A (en) | 2018-09-26 | 2018-09-26 | Anion exchange resin and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109248715A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112756015A (en) * | 2020-12-11 | 2021-05-07 | 安徽皖仪科技股份有限公司 | Anion exchange resin and preparation method and application thereof |
| CN112756016A (en) * | 2020-12-11 | 2021-05-07 | 安徽皖仪科技股份有限公司 | Grafting type anion exchange resin chromatographic packing and preparation method thereof |
| CN113019349A (en) * | 2021-03-02 | 2021-06-25 | 河北欧润科学仪器股份有限公司 | Preparation method of anion chromatographic stationary phase |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4473664A (en) * | 1983-07-20 | 1984-09-25 | Sybron Corporation | Colored inert material for separation of anion and cation resin components |
| US5389449A (en) * | 1991-01-04 | 1995-02-14 | Perseptive Biosystems, Inc. | Sulfonamide bonded hydrophilic coatings |
| CN104945637A (en) * | 2015-06-24 | 2015-09-30 | 浙江大学 | Method for preparing grafting type strong preservation anion chromatographic packing |
| CN107413395A (en) * | 2017-08-30 | 2017-12-01 | 苏州明昊色谱技术有限公司 | A kind of agglomeration type high-hydrophilic strong anion exchanger, preparation method and its application in liquid chromatographic packing materials |
-
2018
- 2018-09-26 CN CN201811123064.5A patent/CN109248715A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4473664A (en) * | 1983-07-20 | 1984-09-25 | Sybron Corporation | Colored inert material for separation of anion and cation resin components |
| US5389449A (en) * | 1991-01-04 | 1995-02-14 | Perseptive Biosystems, Inc. | Sulfonamide bonded hydrophilic coatings |
| CN104945637A (en) * | 2015-06-24 | 2015-09-30 | 浙江大学 | Method for preparing grafting type strong preservation anion chromatographic packing |
| CN107413395A (en) * | 2017-08-30 | 2017-12-01 | 苏州明昊色谱技术有限公司 | A kind of agglomeration type high-hydrophilic strong anion exchanger, preparation method and its application in liquid chromatographic packing materials |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112756015A (en) * | 2020-12-11 | 2021-05-07 | 安徽皖仪科技股份有限公司 | Anion exchange resin and preparation method and application thereof |
| CN112756016A (en) * | 2020-12-11 | 2021-05-07 | 安徽皖仪科技股份有限公司 | Grafting type anion exchange resin chromatographic packing and preparation method thereof |
| CN113019349A (en) * | 2021-03-02 | 2021-06-25 | 河北欧润科学仪器股份有限公司 | Preparation method of anion chromatographic stationary phase |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109248715A (en) | Anion exchange resin and its preparation method and application | |
| CN104014320B (en) | A kind of aqueous metal organic frame molecular engram material of enriched with trace meta-tolyl-N-methylcarbamate (MTMC) | |
| Lei et al. | Hybrid monolithic columns with nanoparticles incorporated for capillary electrochromatography | |
| CN104941611B (en) | The preparation method of graft type high power capacity dendrimer chromatography of ions fixed phase stuffing | |
| Guo et al. | Polystyrene-divinylbenzene-glycidyl methacrylate stationary phase grafted with poly (amidoamine) dendrimers for ion chromatography | |
| Zhang et al. | Preparation of molecularly imprinted ordered mesoporous silica for rapid and selective separation of trace bisphenol A from water samples | |
| CN102935390B (en) | Preparation method of carbon nano tube latex agglomeration type anion chromatographic packing | |
| CN112756016A (en) | Grafting type anion exchange resin chromatographic packing and preparation method thereof | |
| CN107694539B (en) | Novel reversed phase/weak cation exchange mixed mode chromatographic stationary phase and preparation method thereof | |
| CN103949228B (en) | A kind of preparation method of molecular engram magnetic silica gel microball of surface and hydrophilic outer | |
| CN104945631A (en) | Preparation method of novel grafted dendritic macromolecular microspheres | |
| CN104945637A (en) | Method for preparing grafting type strong preservation anion chromatographic packing | |
| Lu et al. | Preparation and evaluation of ionic liquid-gold nanoparticles functionalized silica monolithic column for capillary electrochromatography | |
| WO2015139462A1 (en) | On-line solid-phase extraction column with mono-dispersion and high specific surface area and preparation method therefor | |
| Bruchet et al. | Synthesis and characterization of ammonium functionalized porous poly (glycidyl methacrylate-co-ethylene dimethacrylate) monoliths for microscale analysis and its application to DNA purification | |
| CN107029807A (en) | A kind of preparation method of quick anion chromatographic column packing | |
| CN104289209B (en) | A kind of WCX/HIC for Separation of Proteins difunctional mixed model polymeric matrix chromatographic stationary phases and preparation method thereof | |
| CN102941130B (en) | Preparation method of quaternized carbon nanotube agglomerated anionic chromatographic packing material | |
| CN103949227B (en) | A kind of preparation method of surface and hydrophilic outer hybridization compounding solid phase extraction adsorbents | |
| Carrasco-Correa et al. | Evaluation of 2, 3-epoxypropyl groups and functionalization yield in glycidyl methacrylate monoliths using gas chromatography | |
| Ma et al. | Sulfonated poly (styrene‐divinylbenzene) modified with amines and the application for pipette‐tip solid‐phase extraction of carbendazim in apples | |
| JP4761805B2 (en) | Zinc isotope separation method and apparatus | |
| CN103520955B (en) | Molecular-imprinting integral stirring and adsorbing bar and preparation method thereof | |
| CN106582579A (en) | Four-oxygen naphthalene mixed cup [2] arene [2] triazine bonded silica gel stationary phase and preparation method and application thereof | |
| CN112756015A (en) | Anion exchange resin and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190122 |