CN109224219A - A kind of novel aerosol drug delivery device and its working method by respiratory triggering - Google Patents
A kind of novel aerosol drug delivery device and its working method by respiratory triggering Download PDFInfo
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- CN109224219A CN109224219A CN201811382182.8A CN201811382182A CN109224219A CN 109224219 A CN109224219 A CN 109224219A CN 201811382182 A CN201811382182 A CN 201811382182A CN 109224219 A CN109224219 A CN 109224219A
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- 239000000443 aerosol Substances 0.000 title claims abstract description 44
- 238000012377 drug delivery Methods 0.000 title claims abstract description 44
- 230000000241 respiratory effect Effects 0.000 title claims abstract description 39
- 238000000034 method Methods 0.000 title claims abstract description 17
- 239000003814 drug Substances 0.000 claims abstract description 58
- 238000005507 spraying Methods 0.000 claims abstract description 44
- 239000007921 spray Substances 0.000 claims abstract description 22
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 15
- 238000010079 rubber tapping Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 4
- 238000007373 indentation Methods 0.000 claims description 2
- 229940079593 drug Drugs 0.000 abstract description 36
- 210000000214 mouth Anatomy 0.000 description 11
- 239000003380 propellant Substances 0.000 description 6
- 230000029058 respiratory gaseous exchange Effects 0.000 description 5
- -1 anti-infective Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 238000005381 potential energy Methods 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 2
- LERNTVKEWCAPOY-VOGVJGKGSA-N C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 Chemical compound C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 LERNTVKEWCAPOY-VOGVJGKGSA-N 0.000 description 2
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 description 2
- 239000000556 agonist Substances 0.000 description 2
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 2
- 230000001387 anti-histamine Effects 0.000 description 2
- 230000002924 anti-infective effect Effects 0.000 description 2
- 229940121363 anti-inflammatory agent Drugs 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 239000000739 antihistaminic agent Substances 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 229940092705 beclomethasone Drugs 0.000 description 2
- NBMKJKDGKREAPL-DVTGEIKXSA-N beclomethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O NBMKJKDGKREAPL-DVTGEIKXSA-N 0.000 description 2
- 229960004436 budesonide Drugs 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000812 cholinergic antagonist Substances 0.000 description 2
- 229960002714 fluticasone Drugs 0.000 description 2
- MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 description 2
- 229960002848 formoterol Drugs 0.000 description 2
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 2
- 230000008676 import Effects 0.000 description 2
- 229960001888 ipratropium Drugs 0.000 description 2
- OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 description 2
- 229960001664 mometasone Drugs 0.000 description 2
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 description 2
- 229960002052 salbutamol Drugs 0.000 description 2
- 229960000257 tiotropium bromide Drugs 0.000 description 2
- 108060003345 Adrenergic Receptor Proteins 0.000 description 1
- 102000017910 Adrenergic receptor Human genes 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
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- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000009115 maintenance therapy Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
Abstract
A kind of novel aerosol drug delivery device and its working method by respiratory triggering, drug delivery device include main body A and main body B, are equipped with drug-push lever component in the main body A and main body B；Main body C and main body D, the main body C are connected with main body B, are equipped with spraying medicinal cupping and spray nozzle assembly in the main body C and main body D, the spraying medicinal cupping is inserted in spray nozzle assembly；Suction nozzle cover, the suction nozzle cover are connected with main body D, are equipped with nozzle outlet in the suction nozzle cover and main body D, the spray nozzle assembly is set in nozzle outlet.The novel aerosol drug delivery device by respiratory triggering of the present invention, it is structurally reasonable, it is ingenious in design, securely and reliably, the use needs of user can not only be met, and be conducive to drug storage and take；Air intake passage reasonable pressed gas flow velocity when inhaling medicine, the dispersibility of drug is rationally.
Description
Technical field
The invention belongs to medical equipment technical fields, and in particular, to one kind is novel to be given by the aerosol of respiratory triggering
Medicine device and its working method.
Background technique
Currently, inhalation aerosol can be used in effective treatment to asthma, but many patients exist during clinical use
It is incorrect using method when aerosol.There are many documents to show both at home and abroad, more than half patient when in use, cannot will be effective
The drug delivery of dosage is to lung.Traditional delivery apparatus needs patient to suck inhalator, delivers medicine in inhalator of pressing
While object, does slow and deep air-breathing and hold one's breath the several seconds.This cooperation takes a long time to can be only achieved with multiple practice
Good matching.When cooperating inconsistent, drug can accidentally be delivered to oral cavity or throat, not reach the effect for the treatment of asthma and maintenance
Fruit.Clinically also reflect, patient's maloperation makes it, and confidence is had a greatly reduced quality in use, or even refusal reuses such
Drug affects patient in the maintenance therapy of stationary phase.
Therefore, the above problem is urgently to be resolved.
Summary of the invention
Goal of the invention: for overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of novel by breathing touching
The aerosol drug delivery device of hair and the working method of the drug delivery device.
Technical solution: the present invention provides a kind of novel aerosol drug delivery devices by respiratory triggering, including
Drug-push lever component is equipped in main body A and main body B, the main body A and main body B；
Main body C and main body D, the main body C are connected with main body B, are equipped with spraying medicinal cupping and spray in the main body C and main body D
Nozzle assembly, the spraying medicinal cupping are inserted in spray nozzle assembly；
Suction nozzle cover, the suction nozzle cover are connected with main body D, are equipped with nozzle outlet, the spraying nozzle in the suction nozzle cover and main body D
Component is set in nozzle outlet.
The novel aerosol drug delivery device by respiratory triggering of the present invention, it is structurally reasonable, it is ingenious in design, safely may be used
It leans on, the use needs of user can not only be met, and be conducive to drug storage and take；Air intake passage is reasonably pressed when inhaling medicine
Power gas flow rate, the dispersibility of drug is rationally.Since the patient compliance problem of aerosol products is all generally existing in the whole world
, therefore the aerosol drug delivery device of the present invention by respiratory triggering passes through patient using breathing active drive structure
Active inspiration triggers, to make driving structure itself active pressing aerosol inner canister to deliver drug, reach patient breaths and
Pressing delivers drug cooperation unanimously, solves the problems, such as that effective dose of medicine object is delivered to lung.And it is proper use of in patient
When aerosol, since it is with breathing active drive structure, can more significant raised accuracy, and be delivered to the agent of lung
It measures and is less than labeled dose.This completely new drug delivery device can preferably help patient using drug, and improve compliance
Problem can also help the clearer education patient of medical staff to use this kind of complication system of respiratory tract preparation in clinical use
Drug.By improving patient proper use of drug, precise delivery drug reaches better clinical efficacy.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, the drug-push lever component include pushing away
Medicine bar pedestal, rotating push rod, spring, spring base and self-tapping screw are respectively equipped with shape on the drug-push lever pedestal and rotating push rod
The adaptable inclined-plane of shape, the drug-push lever base sheath are set on rotating push rod；The spring is set on spring base, the spring base
It is fixed on rotating push rod by self-tapping screw.Drug-push lever modular construction is reasonable, can be realized the load and unloading of spring potential energy,
To drive the movement of spraying medicinal cupping.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, the spray nozzle assembly include turning
Dynamic frizzen, release link, medicine mouth lid and spraying nozzle main body, the rotation frizzen are arranged in spraying nozzle main body, the reset
Bar is articulated with rotation frizzen, and the medicine mouth lid is articulated with release link.Spraying nozzle modular construction is reasonable, can be controlled by its rotation
The work for making spraying medicinal cupping, realizes the ejection of drug.
Further, the nozzle of the above-mentioned novel aerosol drug delivery device by respiratory triggering, the spraying medicinal cupping is set
In in spray nozzle assembly, the rotation frizzen is in contact with the nozzle of spraying medicinal cupping；The medicine mouth lid is located in nozzle outlet.
Spraying medicinal cupping is the pressurized canister for accommodating the receiving drug of drug and propellant.Wherein, the drug is dissolved in the propulsion
In agent or the drug is suspended in the propellant.
Wherein, the drug can be selected from the combination being made of the following terms: anti-inflammatory agents, anticholinergic agents, β2-
Adrenoceptor agonists, anti-infective, antihistaminic and their combination.
In addition, the drug can also be selected from the combination being made of the following terms: salbutamol, Formoterol, Sha Mei
Special sieve, fluticasone, budesonide, Mometasone, beclomethasone, Tiotropium Bromide, ipratropium and their combination.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, further includes counting component, the meter
Array part is sheathed on drug-push lever component.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, the counter assembly include meter
Number device presses system, lid, rotary gear shaft, elastic slice, units runner, gear, tens runner and counter main body, the counter master
It is equipped with tens runner in vivo, the tens runner is engaged with gear respectively with units runner；Described cover lower sets respectively
There is counter to engage by system and rotary gear shaft, the rotary gear shaft with units runner, the rotary gear shaft and units runner
Between be additionally provided with elastic slice.Counter assembly is structurally reasonable, can show the pressurized canister for accommodating the receiving drug of drug and propellant
Middle residual drug discharge rate improves the convenience used, and can carry out in time convenient for users to understanding the surplus of drug in time
Drug supplement.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, the main body A are equipped with counter
Window, the counter window are located at units runner and tens runner.Counter window facilitates observation, in addition, conduct
The import of air cooperates nozzle outlet as drug delivery port, and the two limits air flow path together, and the drug of conveying is allocated in
In the air flow path.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering is additionally provided in the nozzle outlet
Push button.Push button can be used for manual releasing drug, easy to use.
The present invention also provides a kind of working methods of novel aerosol drug delivery device by respiratory triggering, including following step
It is rapid:
Main body A is rotated clockwise, main body A drives the rotation of drug-push lever component, and drug-push lever pedestal is rotated together with main body A, and rotation pushes away
Bar is rotated together with main body B, and rotating push rod with the cooperation of the inclined-plane of drug-push lever pedestal by moving down, by spring-compressed；
It is sucked by nozzle outlet or push button is pushed to open medicine mouth lid, release link rotational disengagement, rotation frizzen is overturn, spraying
Medicinal cupping and rotation frizzen disengage, and spraying medicinal cupping moves down spraying medicinal cupping under by the effect of spring strength, the spray of spraying medicinal cupping
Mouth is pressed into medicinal cupping, sprays medicament, is discharged by spraying nozzle main body and nozzle outlet.
The working method of aerosol drug delivery device of the present invention by respiratory triggering, method is reasonable, easy to use, tool
There is high market application prospect.
Further, the working method of the above-mentioned novel aerosol drug delivery device by respiratory triggering,
Main body A is rotated clockwise, rotating push rod drives counter to press downwards by system；
Main body A is rotated counterclockwise, push-rod assembly rotates backward, and rotating push rod is moved up by spring reset, and counter is upward by system
It resets and unclamps, the number shown in the counter window in main body A subtracts 1.Working method is reasonable, and application is convenient.
Further, the working method of the above-mentioned novel aerosol drug delivery device by respiratory triggering, the counter
When component operation, comprising the following steps: rotary gear shaft rotates half-space when counter is pressed by system, passes through elastic slice reset strap when release
Moving gear shaft is rotated further by half-space, while rotary gear shaft drives units runner to rotate a lattice, when units runner rotates ten lattice
When, drive tens runner to rotate a lattice by gear.Counter assembly working method is reasonable, and it is accurate to count.
Above-mentioned technical proposal can be seen that the invention has the following beneficial effects: of the present invention novel by breathing
The aerosol drug delivery device of triggering, it is structurally reasonable, using convenient, using spring potential energy loading structure and respiratory triggering structure,
Structure unloaded spring potential energy under the triggering of respiratory air flow pushes the check (non-return) valve of spraying medicinal cupping and discharges drug, reaches breathing
It controls the purpose that drug quantitatively discharges while recording access times, there is great market application prospect.
Detailed description of the invention
Fig. 1 is the schematic perspective view of the novel aerosol drug delivery device by respiratory triggering of the present invention；
Fig. 2 is the explosive view of the novel aerosol drug delivery device by respiratory triggering of the present invention；
Fig. 3 is the schematic diagram of the section structure of the novel aerosol drug delivery device by respiratory triggering of the present invention；
In figure: 1 main body A, 2 counting components, 2-1 counter are turned by system, 2-2 lid, 2-3 rotary gear shaft, 2-4 elastic slice, 2-5 units
Wheel, 2-6 gear, 2-7 tens runner, 2-8 counter main body, 3 drug-push lever components, 3-1 drug-push lever pedestal, 3-2 rotating push rod,
3-3 spring, 3-4 spring base, 3-5 self-tapping screw, 4 main body B, 5 main body C, 6 spraying medicinal cuppings, 7 spray nozzle assemblies, 7-1 rotation triggering
Bar, 7-2 release link, 7-3 medicine mouth lid, 7-4 spraying nozzle main body, 8 main body D, 9 nozzle outlets, 10 suction nozzle covers, 11 push buttons.
Specific embodiment
The embodiment of the present invention is described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning to end
Same or similar label indicates same or similar element or element with the same or similar functions.Below with reference to attached
The embodiment of figure description is exemplary, it is intended to is used to explain the present invention, and is not considered as limiting the invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", " clockwise ", " inverse
The orientation or positional relationship of the instructions such as hour hands " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description originally
Invention and simplified description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific side
Position construction and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more of the features.In the description of the present invention, unless otherwise indicated, the meaning of " plurality " is two
It is a or more than two, unless otherwise restricted clearly.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc.
Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can be machine
Tool connection, is also possible to be electrically connected；It can be directly connected, two members can also be can be indirectly connected through an intermediary
Connection inside part.For the ordinary skill in the art, above-mentioned term can be understood in this hair as the case may be
Concrete meaning in bright.
In the present invention unless specifically defined or limited otherwise, fisrt feature second feature "upper" or "lower"
It may include that the first and second features directly contact, also may include that the first and second features are not direct contacts but pass through it
Between other characterisation contact.Moreover, fisrt feature includes the first spy above the second feature " above ", " above " and " above "
Sign is right above second feature and oblique upper, or is merely representative of first feature horizontal height higher than second feature.Fisrt feature exists
Second feature " under ", " lower section " and " following " include that fisrt feature is directly below and diagonally below the second feature, or is merely representative of
First feature horizontal height is less than second feature.
Embodiment
The novel aerosol drug delivery device by respiratory triggering as shown in Figure 1, as Figure 2-3, including 1 He of main body A
Counting component 2 and drug-push lever component 3 are equipped in main body B4, the main body A 1 and main body B4, also, the counting component 2 is arranged
In on drug-push lever component 3.Wherein, the counter assembly 2 includes counter by 2-1 processed, lid 2-2, rotary gear shaft 2-3, elastic slice
It is set in 2-4, units runner 2-5, gear 2-6, tens runner 2-7 and counter main body 2-8, the counter main body 2-8
There are tens runner 2-7, the tens runner 2-7 to engage respectively with gear 2-6 with units runner 2-5；On the lid 2-2
Under be respectively equipped with counter by 2-1 processed and rotary gear shaft 2-3, the rotary gear shaft 2-3 is engaged with units runner 2-5, described
Elastic slice 2-4 is additionally provided between rotary gear shaft 2-3 and units runner 2-5.In addition, the drug-push lever component 3 includes drug-push lever bottom
Seat 3-1, rotating push rod 3-2, spring 3-3, spring base 3-4 and self-tapping screw 3-5, the drug-push lever pedestal 3-1 and rotating push rod
The adaptable inclined-plane of shape is respectively equipped on 3-2, the drug-push lever pedestal 3-1 is sheathed on rotating push rod 3-2；The spring 3-
3 are set on spring base 3-4, and the spring base 3-4 is fixed on rotating push rod 3-2 by self-tapping screw 3-5.
In addition, it is above-mentioned it is novel by the aerosol drug delivery device of respiratory triggering further include main body C5 and main body D8, the master
Body C5 is connected with main body B4, is equipped with spraying medicinal cupping 6 and spray nozzle assembly 7, the spray in the main body C5 and main body D8
Tank 6 is inserted in spray nozzle assembly 7.Wherein, the spray nozzle assembly 7 includes rotation frizzen 7-1, release link 7-2, medicine mouth lid
7-3 and spraying nozzle main body 7-4, the rotation frizzen 7-1 are arranged in spraying nozzle main body 7-4, and the release link 7-2 is articulated with
Frizzen 7-1 is rotated, the medicine mouth lid 7-3 is articulated with release link 7-2.Also, the nozzle of the spraying medicinal cupping 6 is set to spraying nozzle
In component 7, the rotation frizzen 7-1 is in contact with the nozzle of spraying medicinal cupping 6；The medicine mouth lid 7-3 is located at nozzle outlet 9
It is interior.Spraying medicinal cupping 6 is the pressurized canister for accommodating the receiving drug of drug and propellant.Wherein, the drug is dissolved in described
In propellant or the drug is suspended in the propellant.Wherein, the drug can be selected from and is made of the following terms
Combination: anti-inflammatory agents, anticholinergic agents, β2Adrenoceptor agonists, anti-infective, antihistaminic and they
Combination.In addition, the drug can also be selected from the combination being made of the following terms: salbutamol, Formoterol, Sha Meite
Sieve, fluticasone, budesonide, Mometasone, beclomethasone, Tiotropium Bromide, ipratropium and their combination.
In addition, it is above-mentioned it is novel by the aerosol drug delivery device of respiratory triggering further include suction nozzle cover 10, the suction nozzle cover
10 are connected with main body D8, are equipped with nozzle outlet 9 in the suction nozzle cover 10 and main body D8, the spray nozzle assembly 7 is set to suction nozzle
In channel 9.In addition, being additionally provided with push button 11 in the nozzle outlet 9.
Further, the above-mentioned novel aerosol drug delivery device by respiratory triggering, the main body A 1, which is equipped with, to be counted
Device window, the counter window are located at units runner 2-5 and tens runner 2-7.Counter window facilitates observation, this
Outside, as the import of air, nozzle outlet 9 is cooperated to be used as drug delivery port, the two limits air flow path, the medicine of conveying together
Object is allocated in the air flow path.
It is basic based on above structure including following when the above-mentioned novel aerosol drug delivery device by respiratory triggering works
Step:
Main body A 1 is rotated clockwise, main body A 1 drives drug-push lever component 3 to rotate, and drug-push lever pedestal 3-1 is rotated together with main body A 1,
Rotating push rod 3-2 is rotated together with main body B4, and rotating push rod 3-2 with the cooperation of the inclined-plane of drug-push lever pedestal 3-1 by moving down, by bullet
Spring 3-3 compression；Main body A 1 is rotated clockwise simultaneously, and rotating push rod 3-2 drives counter to press downwards by 2-1 processed；
Suck or push push button 11 to open medicine mouth lid 10 by nozzle outlet 9, release link 7-2 rotational disengagement rotates frizzen
7-1 overturning, spraying medicinal cupping 6 are disengaged with rotation frizzen 7-1, and spraying medicinal cupping 6 makes spraying medicinal cupping 6 under by the effect of spring 3-3 strength
It moves down, in the nozzle indentation medicinal cupping of spraying medicinal cupping 6, sprays medicament, pass through 9 row of spraying nozzle main body 7-4 and nozzle outlet
Out.
Main body A 1 is rotated counterclockwise, push-rod assembly 3 rotates backward, and rotating push rod 3-2 is moved up by the reset of spring 33, counts
Device resets release by 2-1 processed upwards, and the number shown in the counter window in main body A 1 subtracts 1.
When above-mentioned counter assembly 2 works, comprising the following steps: rotary gear shaft 2-3 is rotated when counter is pressed by 2-1 processed
Half-space is rotated further by half-space by elastic slice 2-4 reset strap moving gear shaft 2-3 when release, while rotary gear shaft 2-3 drives units
Runner 2-5 rotates a lattice, when units runner 2-5 rotates ten lattice, drives tens runner 2-7 rotation one by gear 2-6
Lattice.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the principle of the present invention, several improvement can also be made, these improvement also should be regarded as of the invention
Protection scope.
Claims (10)
1. a kind of novel aerosol drug delivery device by respiratory triggering, it is characterised in that: including
Main body A (1) and main body B(4), the main body A (1) and main body B(4) it is interior equipped with drug-push lever component (3)；
Main body C(5) and main body D(8), the main body C(5) it is connected with main body B(4), the main body C(5) and main body D(8) in
Equipped with spraying medicinal cupping (6) and spray nozzle assembly (7), spraying medicinal cupping (6) are inserted in spray nozzle assembly (7)；
Suction nozzle cover (10), the suction nozzle cover (10) are connected with main body D(8), the suction nozzle cover (10) and main body D(8) in be equipped with
Nozzle outlet (9), the spray nozzle assembly (7) are set in nozzle outlet (9).
2. the novel aerosol drug delivery device by respiratory triggering according to claim 1, it is characterised in that: described to push away medicine
Bar assembly (3) includes drug-push lever pedestal (3-1), rotating push rod (3-2), spring (3-3), spring base (3-4) and self-tapping screw (3-
5) the adaptable inclined-plane of shape, the drug-push lever bottom, are respectively equipped on the drug-push lever pedestal (3-1) and rotating push rod (3-2)
Seat (3-1) is sheathed on rotating push rod (3-2)；The spring (3-3) is set on spring base (3-4), and the spring base (3-4) is logical
Self-tapping screw (3-5) is crossed to be fixed on rotating push rod (3-2).
3. the novel aerosol drug delivery device by respiratory triggering according to claim 1, it is characterised in that: the spray
Nozzle assembly (7) includes rotating frizzen (7-1), release link (7-2), medicine mouth lid (7-3) and spraying nozzle main body (7-4), and described turn
Dynamic frizzen (7-1) is arranged in spraying nozzle main body (7-4), and the release link (7-2) is articulated with rotation frizzen (7-1), institute
It states medicine mouth lid (7-3) and is articulated with release link (7-2).
4. the novel aerosol drug delivery device by respiratory triggering according to claim 3, it is characterised in that: described spraying
The nozzle of medicinal cupping (6) is set in spray nozzle assembly (7), and rotation frizzen (7-1) connects with the nozzle of spraying medicinal cupping (6)
Touching；The medicine mouth lid (7-3) is located in nozzle outlet (9).
5. the novel aerosol drug delivery device by respiratory triggering according to claim 1-4, it is characterised in that:
It further include counting component (2), the counting component (2) is sheathed on drug-push lever component (3).
6. the novel aerosol drug delivery device by respiratory triggering according to claim 5, it is characterised in that: the counting
Device assembly (2) include counter by system (2-1), lid (2-2), rotary gear shaft (2-3), elastic slice (2-4), units runner (2-5),
Gear (2-6), tens runner (2-7) and counter main body (2-8), the counter main body (2-8) is interior to be turned equipped with tens
It takes turns (2-7), the tens runner (2-7) is engaged with gear (2-6) respectively with units runner (2-5)；On the lid (2-2)
Under be respectively equipped with counter by system (2-1) and rotary gear shaft (2-3), the rotary gear shaft (2-3) is nibbled with units runner (2-5)
It closes, is additionally provided with elastic slice (2-4) between the rotary gear shaft (2-3) and units runner (2-5).
7. the novel aerosol drug delivery device by respiratory triggering according to claim 1-4, it is characterised in that:
Push button (11) are additionally provided on the nozzle outlet (9).
8. a kind of working method of the novel aerosol drug delivery device by respiratory triggering, it is characterised in that: the following steps are included:
It rotates clockwise main body A (1), main body A (1) drives drug-push lever component (3) rotation, drug-push lever pedestal (3-1) same to main body A
(1) rotate together, rotating push rod (3-2) is rotated together with main body B(4), rotating push rod (3-2) by with drug-push lever pedestal (3-
1) inclined-plane cooperation moves down, and spring (3-3) is compressed；
It is sucked by nozzle outlet (9) or push button (11) is pushed to open medicine mouth lid (10), release link (7-2) rotational disengagement turns
Dynamic frizzen (7-1) overturning, spraying medicinal cupping (6) and rotation frizzen (7-1) disengage, and spraying medicinal cupping (6) are by spring (3-3) strength
It moves down spraying medicinal cupping (6) under effect, in the nozzle indentation medicinal cupping of spraying medicinal cupping (6), sprays medicament, pass through spraying nozzle
Main body (7-4) and nozzle outlet (9) discharge.
9. the working method of the novel aerosol drug delivery device by respiratory triggering according to claim 8, feature exist
In:
It rotates clockwise main body A (1), rotating push rod (3-2) drives counter to press downwards by system (2-1)；
It rotating counterclockwise main body A (1), push-rod assembly (3) rotates backward, and rotating push rod (3-2) is resetted by spring (33) to be moved up,
Counter is resetted upwards by system (2-1) and is unclamped, and the number shown in the counter window in main body A (1) subtracts 1.
10. the working method of the novel aerosol drug delivery device by respiratory triggering according to claim 9, feature exist
In: when the counter assembly (2) works, comprising the following steps: rotary gear shaft (2-3) turns when counter is pressed by system (2-1)
Dynamic half-space is rotated further by half-space, while rotary gear shaft (2-3) band by elastic slice (2-4) reset strap moving gear shaft (2-3) when release
Dynamic units runner (2-5) rotates a lattice, when units runner (2-5) rotates ten lattice, drives tens by gear (2-6)
Runner (2-7) rotates a lattice.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811382182.8A CN109224219A (en) | 2018-11-20 | 2018-11-20 | A kind of novel aerosol drug delivery device and its working method by respiratory triggering |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811382182.8A CN109224219A (en) | 2018-11-20 | 2018-11-20 | A kind of novel aerosol drug delivery device and its working method by respiratory triggering |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115025341A (en) * | 2022-05-28 | 2022-09-09 | 山东京卫制药有限公司 | Aerosol automatic pressing actuator, monitoring method and application |
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| US20140202458A1 (en) * | 2011-01-20 | 2014-07-24 | Pneumoflex Systems, Llc | Metered dose atomizer |
| CN207562183U (en) * | 2017-05-16 | 2018-07-03 | 詹枝华 | Inspiration trigger formula chemical spraying device |
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| US20130239956A1 (en) * | 2010-11-24 | 2013-09-19 | Pari Pharma Gmbh | Aerosol generator |
| US20140202458A1 (en) * | 2011-01-20 | 2014-07-24 | Pneumoflex Systems, Llc | Metered dose atomizer |
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