CN109200471A - DBS location of operation head frame and its manufacturing method - Google Patents
DBS location of operation head frame and its manufacturing method Download PDFInfo
- Publication number
- CN109200471A CN109200471A CN201811323588.9A CN201811323588A CN109200471A CN 109200471 A CN109200471 A CN 109200471A CN 201811323588 A CN201811323588 A CN 201811323588A CN 109200471 A CN109200471 A CN 109200471A
- Authority
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- China
- Prior art keywords
- head frame
- dbs
- location
- positioning head
- positioning
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37514—Brain implants
Abstract
The present invention relates to the field of medical instrument technology, more particularly, to a kind of DBS location of operation head frame and its manufacturing method.The DBS location of operation head frame includes: positioning head frame ontology, and the positioning head frame ontology is manufactured using 3D printing technique；Fixation kit, the fixation kit are arranged on the positioning head frame ontology.The present invention can be directed to the different situations of different patients by 3D printing technique, and produce and the matched DBS location of operation head frame of patient of customization may be implemented accurately to position, and can effectively reduce operating time, reduce patients surgery risk.It is manufactured using 3D printing technique, can personalize manufacture, auxiliary that can be more accurate is implanted into brain stimulation element.
Description
Technical field
The present invention relates to the field of medical instrument technology, more particularly, to a kind of DBS location of operation head frame and its manufacturing method.
Background technique
DBS (Deep brain stimulation) therapy, is a kind of deep brain stimulation therapy, genetic for treating
Myodystony can obviously improve the state of an illness.Electrode is mainly implanted to patient's intracerebral by DBS therapy, is pierced with impulse generator
The certain nerve nucleus for swashing brain in patients deep, correct abnormal brain electricity loop, to mitigate these neurological symptoms.With
Some treatment methods (burn or radiotherapy) of permanent unadjustable and irreversible damaged brain are different, and DBS is not destroyed
Brain structure can permit further treatment from now on.
When carrying out DBS therapy, it is often necessary to use a kind of location of operation head frame.
Currently, the tridimensional orienting headstock that the fields such as well known neurosurgery and neurotomy use, structure is derived from more
In a plurality of tridimensional orienting headstocks of last century later half design, two types can be divided by positioning method tridimensional orienting headstock: arc
Target is placed in the center of direction finder arc bow by head frame (polar coordinate system)；Square spigot frame (rectangular coordinate system), passes through bilayer
Grid enters through side and volume approach.
Instantly the tridimensional orienting headstock manufactured, the microelectrode positioning being able to satisfy in DBS operation substantially, electrode insertion waited
Journey.But existing stereoscopic localized head frame can not match with the concrete condition of every patient, it is insufficient that there are positioning accuracies
Disadvantage.
Summary of the invention
The purpose of the present invention is to provide a kind of DBS location of operation head frame and its manufacturing methods, to solve in the prior art
The low technical problem of positioning head frame precision.
The present invention provides a kind of DBS location of operation head frame, comprising:
Positioning head frame ontology, the positioning head frame ontology are manufactured using 3D printing technique；
Fixation kit, the fixation kit are arranged on the positioning head frame ontology.
Further, the positioning head frame ontology includes frame and locating part, and the locating part is arranged on said frame,
The limit hole for being positioned to the brain stimulation element being inserted into is equipped in locating part.
Further, the locating part is one, and the locating part is arranged in left and right side the two of the frame
Wherein side；
Or the locating part is two, and one in two locating parts is arranged in the left side of the frame, and two
Another in a locating part is arranged on the right side of the frame.
Further, the frame is equipped with jack, the fixation kit and passes through the jack and the frame grafting.
Further, the fixation kit includes left fixing piece and the setting that positioning head frame ontology one end is arranged in
In the right fixing piece of the other end of the positioning head frame ontology.
Further, the fixation kit further includes the rear fixing piece that the rear side of the positioning head frame ontology is arranged in.
Further, the material of the fixation kit is titanium alloy.
The present invention also provides a kind of manufacturing methods of DBS location of operation head frame, include the following steps:
Step S1, the target spot of patient and the coordinate position of brain are determined；
Step S2, the coordinate position of the target spot of the patient and brain is converted into the 3D model of positioning head frame ontology；
Step S3, positioning head frame ontology is printed using 3D printing technique；
Step S4, fixation kit is assembled on positioning head frame ontology.
Further, step S1 obtains the target spot of patient and the coordinate position of brain using three-dimensional developing technique.
Further, in step S2, the 3D model of positioning head frame ontology is established using three-dimensional drafting instrument.
The present invention can be directed to the different situations of different patients by 3D printing technique, customization produce and patient
Matched DBS location of operation head frame, the DBS location of operation head frame that each patient uses are that specially had according to the head of the patient
Body situation custom-made, be not general popular positioning head frame, it is thereby achieved that accurately positioning, Ke Yiyou
The reduction operating time of effect reduces patients surgery risk.It is manufactured using 3D printing technique, can personalize manufacture, it can be more
Add accurate auxiliary implantation brain stimulation element.In addition, entire DBS location of operation head frame structure is simple, and it is easily manufactured, it is at low cost.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art
Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below
Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of DBS location of operation head frame provided in an embodiment of the present invention；
Fig. 2 is the structural schematic diagram of the location of operation head frame ontology in Fig. 1；
Fig. 3 is the structural schematic diagram of DBS location of operation head frame provided by Embodiment 2 of the present invention；
Fig. 4 is the structural schematic diagram for the DBS location of operation head frame that the embodiment of the present invention three provides；
Fig. 5 is the flow diagram of the manufacturing method of DBS location of operation head frame provided by the invention.
Appended drawing reference:
1, positioning head frame ontology；2, fixation kit；11, frame；12, locating part；13, jack；14, connecting plate；21, Zuo Gu
Determine part；22, right fixing piece；23, rear fixing piece；121, limit hole；131, left jack；132, right jack；133, rear jack；
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation
Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill
Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", "vertical",
The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to
Convenient for description the present invention and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation,
It is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
To be to be connected directly, the connection inside two elements can also be can be indirectly connected through an intermediary.For this field
For those of ordinary skill, the concrete meaning of above-mentioned term in the present invention can be understood with concrete condition.
Fig. 1 is the structural schematic diagram of DBS location of operation head frame provided in an embodiment of the present invention；Fig. 2 is that the operation in Fig. 1 is fixed
The structural schematic diagram of potential head frame ontology.
According to an aspect of the present invention, a kind of DBS location of operation head frame is provided, as depicted in figs. 1 and 2, comprising: positioning
Head frame ontology 1, the positioning head frame ontology 1 is manufactured using 3D printing technique；Fixation kit 2, the fixation kit 2 are arranged in institute
It states on positioning head frame ontology 1.
In use, positioning head frame ontology 1 to be set in the head of patient, using fixation kit 2 by head frame ontology and patient
Head is fixed, and prevents from loosening.
Manufacturing technology of the 3D printing as newest rise changes traditional machine and adds or mold molding mode, can be quick
Entity shaping after realizing modeling.DBS stereoscopic localized head frame is manufactured using 3D printing technique, producing for capable of customizing is high-precision
The positioning head frame of degree.It may make DBS operation more efficient, brain stimulation element (microstimulation needle, electrode etc.) is implanted into the position of target spot more
Accurately.Adjusting and improvement sufferer to postoperative stimulation parameter is more advantageous.
The present invention can be directed to the different situations of different patients by 3D printing technique, customization produce and patient
Matched DBS location of operation head frame, the DBS location of operation head frame that each patient uses are that specially had according to the head of the patient
Body situation custom-made, be not general popular positioning head frame, it is thereby achieved that accurately positioning, Ke Yiyou
The reduction operating time of effect reduces patients surgery risk.It is manufactured using 3D printing technique, cost is relatively low.In addition, entire DBS hand
Art positioning head frame structure is simple, easily manufactured, at low cost.
Specifically, as shown in Fig. 2, the positioning head frame ontology 1 includes frame 11 and locating part 12, the locating part 12 is set
It sets on the frame 11, the limit hole 121 for being positioned to the brain stimulation element being inserted into is equipped in locating part 12.It is logical
It crosses limit hole 121 and is inserted into brain stimulation element.Wherein, brain stimulation element, which can be, prays for that needle, electrode etc. is stimulated to be used for needed for operation
The element that patients head is stimulated.
In the present embodiment, frame 11 can be the frame of rectangle, or the frame of arc, it is preferable that frame 11
For the frame of arc, to be adapted with the contouring head of patient.Locating part 12 can be column, boss-shaped, such as locating part
12 can be the various suitable shapes such as cylindric, flat column.Frame 11 and locating part 12 are made into integration using 3D printing technique.
Preferably, locating part 12 is cylindric.
Limit hole 121 in locating part 12 can match with the outer profile for the brain stimulation element being inserted into, so as to accurate
Positioning.Preferably, limit hole 121 is circular hole
Preferably, locating part 12 and the fixation kit 2 are spaced apart, to avoid interfering.
Sufferer is divided into left side lesion, right side lesion or bilateral and lesion all occurs.According to the different situations of patient, the present invention is done
Different DBS location of operation head frame.
In one embodiment of the invention, a kind of single channel DBS location of operation head frame is provided, wherein the locating part
12 be one, and the wherein side in left and right side the two of the frame 11 is arranged in the locating part 12；It can be to unilateral side
The patient of lesion.
Specifically, referring to Fig. 3, locating part 12 be can be set in the left side of the positioning head frame ontology 1, form single channel
(left side) DBS location of operation head frame, the DBS location of operation head frame of this form are suitable for controlling the patient of left side lesion
It treats.
Referring to Fig. 1, locating part 12 be can be set on the right side of the positioning head frame ontology 1, form single channel (right side) DBS
Location of operation head frame, the DBS location of operation head frame of this form are suitable for treating the patient of right side lesion.
In the present embodiment, a kind of formation binary channels DBS location of operation head frame is provided, referring to fig. 4, the locating part 12 is
Two, one in two locating parts 12 be arranged in it is another in the left side of the frame 11, two locating parts 12
One is arranged on the right side of the frame 11, treats suitable for the patient to bilateral lesion.
To sum up, the present invention provides the DBS location of operation head frame of three kinds of specifications, it can satisfy different lesions type patient's
Demand.
In addition, as shown in Fig. 2, the frame 11 is equipped with jack 13, the fixation kit 2 with by the jack 13 with
11 grafting of frame.
In the present invention, remaining structure in addition to fixation kit 2 is all made of 3D printing technique manufacture, so that frame 11,
Limit hole 121 and jack 13 in locating part 12, locating part 12 etc., which are able to carry out, accurately to be manufactured, and ensure that positioning
Precision, meanwhile, 1 structure of positioning head frame ontology being made into integration using 3D printing technique is simple, at low cost, reliable performance.
Wherein, referring to Fig. 3, the fixation kit 2 includes the left fixing piece 21 that described 1 one end of positioning head frame ontology is arranged in
And the right fixing piece 22 of the other end of the positioning head frame ontology 1 is set.Left fixing piece 21 is used for the left side to patients head
Side is fixed, and right fixing piece 22 is used for being fixed on the right side of patients head.Pass through left fixing piece 21 and right fixing piece 22
DBS location of operation head frame can be fixed on to the head of patient well.
Specifically, jack 13 includes that the left jack 131 of the left end of positioning head frame ontology 1 is arranged in and is arranged in positioning head frame
The right jack 132 of the right end of ontology 1, left fixing piece 21 are plugged in left jack 131, and right fixing piece 22 is plugged on right jack 132
In.
In addition, the fixation kit 2 further includes the rear fixing piece 23 that the rear side of the positioning head frame ontology 1 is arranged in.Afterwards
Fixing piece 23 further fixes positioning head frame ontology 1 from the rear portion of patient.
In order to facilitate fixation, it is preferable that as shown in Fig. 2, the middle part of positioning head frame ontology 1 is equipped with connecting plate 14, the company
Fishplate bar 14 is equipped with rear jack 133, and rear fixing piece 23 is by being plugged in rear jack 133.
Fixation kit 2 (including left fixing piece 21, right fixing piece 22 and rear fixing piece 23) mentioned above can be fixation
The form of column.Specifically, positioning column can include the first inserting column and insertion jack outside jack 13 in step type, positioning column
The second inserting column in 13, the diameter of first inserting column are greater than the diameter of second inserting column.
Above-mentioned fixation kit 2 can individually customize manufacture, can also be made of standard component, and specification and size are fixed, with
It can prepare in batches, reduce manufacturing cost.
Further, the positioning head frame ontology 1 is printed using hard high molecular material, such as rigid plastics etc., in this way
1 structural rigidity of positioning head frame ontology printed is good, will not be deformed and move, can further increase positioning accuracy.
Further, the material of fixation kit 2 can be made of the stronger material of rigidity, to meet wanting for positioning accuracy
It asks.Optionally, the material of fixation kit 2 is titanium alloy, can further increase positioning accuracy.In addition, solid made of titanium alloy
It is high to determine 2 intensity of component, corrosion resistance is good, and light weight, is easy to use.
Fig. 5 is the flow diagram of the manufacturing method of DBS location of operation head frame provided by the invention.
As shown in figure 5, according to another aspect of the present invention, providing a kind of DBS location of operation head according to the present invention
The manufacturing method of frame, includes the following steps:
Step S1, the target spot of patient and the coordinate position on head are determined；
Step S2, the coordinate position of the target spot of the patient and head is converted into the 3D model of positioning head frame ontology 1；
Step S3, positioning head frame ontology 1 is printed using 3D printing technique；
Step S4, fixation kit 2 is assembled on positioning head frame ontology 1, forms complete DBS location of operation head frame.
When medically carrying out certain radiotherapies, radioactive ray irradiate from different directions, collect diseased region, this lesion
Position is called target spot.Wherein, locating part 12 is corresponding with target spot, that is, diseased region of patient.
Wherein it is determined that can determine the fixed bit of positioning head frame ontology 1 after the spatial coordinate location of stimulation target spot and brain
Set coordinate (i.e. 1 upper limit of positioning head frame ontology of (installation site of the fixation kit 2 i.e. on DBS location of operation head frame) and target spot
The position of position part 12).
Further, step S1 obtains the target spot of patient and the coordinate position on head using three-dimensional developing technique, in this way may be used
To improve the precision of the target spot of acquisition patient and the coordinate position on head, guarantee the high-precision of collected information.
Specifically, three-dimensional developing technique can be MRT (magnetic resonance imaging) Magnetic resonance imaging
Technology or CT (computerized tomographic scanning) computed tomography.
Further, in step S2, the 3D model of positioning head frame ontology 1 is established using three-dimensional drafting instrument.Wherein, three-dimensional
Drafting instrument can be 3DMAX, Pro/Engineer or Solidworks etc..Three-dimensional drafting instrument can be accurately by the trouble
The target spot of person and the coordinate position on head are converted into the 3D model of positioning head frame ontology 1；So that the 3D model accuracy established is high, this
The precision for the DBS location of operation head frame ontology 1 that sample prints is high.
In addition, in the present embodiment, the manufacturing method of DBS location of operation head frame further includes detecting step, positioning is produced
It after head frame ontology 1, is detected, detects the production quality of positioning head frame ontology 1, after up-to-standard, delivered hospital and use.Quality
It is underproof, it can give up.
Specifically, to the patient of suitable DBS operation, pass through stereotaxis Imaging Technology (MRI, CT etc.).Determine stimulation
The spatial coordinate location of target spot and brain determines fixation position (i.e. the position of fixation kit 2) and the target spot of positioning head frame ontology 1
Coordinate (i.e. the position of locating part 12), determine electrode implantation point coordinate position.The patient is established by D modeling tool
Positioning head frame ontology 1 model.Processing factory is fed back, by 3D printing technique, produces surgical head rest, detector frame system
Make quality, is delivered for use.It is constituted according to different patient's target spots and brain space coordinate, the limit hole 121 on locating part 12
Direction and distance apart from target spot generate corresponding variation.
The present invention determines the target spot of patient and the coordinate position on head first；Again by the seat of the target spot of the patient and head
Cursor position is converted into the 3D model of positioning head frame ontology 1；Then positioning head frame ontology 1 is printed using 3D printing technique.It can be with
According to the concrete condition of each patient, accurately customize out with the matched DBS location of operation head frame ontology 1 of the patient, may be implemented
It accurately positions, can effectively reduce operating time, reduce patients surgery risk.Manufactured using 3D printing technique, cost compared with
It is low.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of DBS location of operation head frame characterized by comprising
Positioning head frame ontology, the positioning head frame ontology are manufactured using 3D printing technique；
Fixation kit, the fixation kit are arranged on the positioning head frame ontology.
2. DBS location of operation head frame according to claim 1, which is characterized in that the positioning head frame ontology includes frame
And locating part, the locating part setting are equipped on said frame, in locating part for carrying out to the brain stimulation element being inserted into
The limit hole of positioning.
3. DBS location of operation head frame according to claim 2, which is characterized in that
The locating part is one, and the wherein side in left and right side the two of the frame is arranged in the locating part；
Or the locating part is two, one in two locating parts is arranged in the left side of the frame, two institutes
Another stated in locating part is arranged on the right side of the frame.
4. DBS location of operation head frame according to claim 2, which is characterized in that
The frame is equipped with jack, and the fixation kit passes through the jack and the frame grafting.
5. DBS location of operation head frame described in any one of -4 according to claim 1, which is characterized in that the fixation kit packet
It includes the left fixing piece that positioning head frame ontology one end is set and the right side of the other end of the positioning head frame ontology is set
Fixing piece.
6. DBS location of operation head frame according to claim 5, which is characterized in that the fixation kit further includes that setting exists
The rear fixing piece of the rear side of the positioning head frame ontology.
7. DBS location of operation head frame described in any one of -4 according to claim 1, which is characterized in that the fixation kit
Material is titanium alloy.
8. a kind of manufacturing method of DBS location of operation head frame described in any one of -7 according to claim 1, which is characterized in that
Include the following steps:
Step S1, the target spot of patient and the coordinate position of brain are determined；
Step S2, the coordinate position of the target spot of the patient and brain is converted into the 3D model of positioning head frame ontology；
Step S3, positioning head frame ontology is printed using 3D printing technique；
Step S4, fixation kit is assembled on positioning head frame ontology.
9. manufacturing method according to claim 8, which is characterized in that step S1 obtains patient's using three-dimensional developing technique
The coordinate position of target spot and brain.
10. manufacturing method according to claim 8, which is characterized in that in step S2, it is fixed to be established using three-dimensional drafting instrument
The 3D model of potential head frame ontology.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811323588.9A CN109200471A (en) | 2018-11-07 | 2018-11-07 | DBS location of operation head frame and its manufacturing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811323588.9A CN109200471A (en) | 2018-11-07 | 2018-11-07 | DBS location of operation head frame and its manufacturing method |
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| CN109200471A true CN109200471A (en) | 2019-01-15 |
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| CN201811323588.9A Pending CN109200471A (en) | 2018-11-07 | 2018-11-07 | DBS location of operation head frame and its manufacturing method |
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| US20170291044A1 (en) * | 2014-12-26 | 2017-10-12 | Shenzhen Institutes Of Advanced Technology Chinese Academy Of Sciences | Ultrasound deep brain stimulation method and system |
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| CN103690243A (en) * | 2013-12-20 | 2014-04-02 | 中国人民解放军第二军医大学 | Stereotactic head frame and surgery lying plate applicable to DSA (Digital Subtraction Angiography) machine minimally invasive surgery |
| US20170291044A1 (en) * | 2014-12-26 | 2017-10-12 | Shenzhen Institutes Of Advanced Technology Chinese Academy Of Sciences | Ultrasound deep brain stimulation method and system |
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