CN109192308A - A kind of early screening system of peripheral arteriosclerosis - Google Patents

A kind of early screening system of peripheral arteriosclerosis Download PDF

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Publication number
CN109192308A
CN109192308A CN201811298283.7A CN201811298283A CN109192308A CN 109192308 A CN109192308 A CN 109192308A CN 201811298283 A CN201811298283 A CN 201811298283A CN 109192308 A CN109192308 A CN 109192308A
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module
result
data
pulse wave
wave signal
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辛宏
李程亮
张科林
王敏娟
蔡天志
王美雪
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First Affiliated Hospital Of Xi'an Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T17/00Three dimensional [3D] modelling, e.g. data description of 3D objects
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

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Abstract

The invention discloses a kind of early screening systems of peripheral arteriosclerosis, comprising: human-machine operation module, pulse wave signal acquisition module, blood flow signal acquisition module, data preprocessing module, human body artery model construction module, virtual actuator, virtual parameter module, simulation analysis module, forecast analysis module, inspection result display module, graphic plotting module, comparative analysis module and control prece decision-premaking module.The present invention realizes the building of artery threedimensional model by human body artery model construction module, healthcare givers is facilitated to the simulation analysis of testing result, to realize the conversion of diagnostic data, improve the comprehensive and accuracy of diagnostic result, and realize the prediction of artery future development situation and the decision-premaking of control prece;The visual presentation of testing result is realized, gets information about current artery state convenient for healthcare givers and patient.

Description

A kind of early screening system of peripheral arteriosclerosis
Technical field
The present invention relates to medical fields, and in particular to a kind of early screening system of peripheral arteriosclerosis.
Background technique
Artery sclerosis is to seriously affect the primary disease of human health status, passes through early stage accurate, noninvasive sieve for it It looks into and prevents to be to improve the measure that human life's mass is effective, easy, risk is small, inexpensive.At present frequently with by pulse Wave signal, blood flow signal etc. are handled, to obtain the index of artery sclerosis.However, being led at present in the processing of pulse wave signal In domain, whether existing commercialized product, or related theory is based on Time Domain Processing technology.Time Domain Processing is answered in clinic Although efficiently solving the case in portion artery sclerosis early screening in, it still has clinical use Limitation and contingency.For example, the development trend of disease, the initial stage for thrombosis and aortic smooth cannot be assessed accurately The variation of flesh early stage degeneration is difficult to find.
Summary of the invention
To solve the above problems, the present invention provides a kind of early screening system of peripheral arteriosclerosis,.
To achieve the above object, the technical scheme adopted by the invention is as follows:
A kind of early screening system of peripheral arteriosclerosis, comprising:
Human-machine operation module, for inputting patient basis and funduscopy result data;
Pulse wave signal acquisition module carries out patient body pulse wave signal everywhere based on infrared electro data pick-up Acquisition;
Blood flow signal acquisition module carries out adopting for lumen of vessels form and blood flow state data based on supersonic doppler detector Collection;
Data preprocessing module, by depth convolution model respectively to the funduscopy result data of acquisition, everywhere pulse Wave signal and lumen of vessels form and blood flow state data carry out feature extraction;
Human body artery model construction module according to the patient basis and extracts resulting spy based on Simulink Levy the building that data carry out human body artery model emulation model;
Virtual actuator is established with each element in human body artery model construction module and is closed for driving Parameters variation After system, parameter can be changed in specified range, be directed to different parameters so as to driving simulation analysis method Carry out calculating solution;And the position for changing transfering node, direction setting, it realizes human body artery model sport, decomposes, cuts It cuts, amplify and reduces;
Virtual parameter module, for the target that can directly acquire corresponding result or information being inserted into human body artery model Logic unit;
Simulation analysis module, the control command for being inputted according to human-computer interaction module drive corresponding simulation analysis algorithm To the virtual actuator, virtual actuator circulation executes the simulation analysis algorithm and result is fed back to simulation analysis module, The simulation analysis module automatically extracts target component and gives virtual parameter module, and the virtual parameter module is received and shown automatically Target component;
Forecast analysis module establishes short-term forecast unit using statistical regression and data-driven method, obtained by extracting Characteristic generate short-term artery and develop forecast information;
It further, further include an inspection result display module, by obtaining blood corresponding under different pulse wave signals Lumen form and blood flow state data establish pulse wave signal and lumen of vessels form and blood flow on the basis of gained pulse wave signal The PLSR model of status data obtains the pulse wave signal of each pixel on image, is made by way of being converted into color-values The pulse wave signal distribution situation of each pixel visualizes.
Further, further includes:
Graphic plotting module, for according to the funduscopy result data, everywhere pulse wave signal and lumen of vessels shape State and blood flow state data draw various visualized graphs;
Comparative analysis module will draw visualized graphs and visualized graphs and last inspection knot under normal circumstances The corresponding visualized graphs of fruit compare and analyze and predict that prediction result is analyzed in output.
Further, further includes:
Control prece decision-premaking module analyzes result for the typical human body artery model emulation model emulation of store various types And its corresponding control prece model, for each simulation analysis result received to be carried out similar degree pair with the data stored Than, and by comparison result according to similarity carry out ascending or descending order sequence after, be sent to human-machine operation module and shown.
Further, the graphic plotting module is used for the control command inputted according to human-machine operation module, calls corresponding Data source of the mapping program based on selection and drawing require, complete the automatic drafting of figure.
Further, the comparative analysis module is called for the control command for being inputted according to human-machine operation module Corresponding visualized graphs of the comparative analysis program based on selection, complete the automatic comparative analysis of multiple figures, and export analysis Prediction result.
Further, further include a three-dimensional display module, be situated between by moulding light modules, using phantom imaging film as imaging Optical imagery module, video display playing module, computer media module and the control module composition of matter, are erected at diagnosis and treatment doctor's It is dynamic for calling corresponding data to generate in materials database according to the resulting result of inspection result display module on desk Arteries and veins three-dimensional stereo model.
The invention has the following advantages:
The building that artery threedimensional model is realized by human body artery model construction module facilitates healthcare givers to detection As a result simulation analysis, to realize the conversion of diagnostic data, such as by pulse wave signal and lumen of vessels form and blood flow shape Condition data conversion is at data a possibility that thrombosis, by different zones pulse wave signal and blood flow state data conversion at blood Bolt is likely to form the prediction etc. of position, improves the comprehensive and accuracy of diagnostic result, and realizes artery future development feelings The prediction of condition and the decision-premaking of control prece;The visual presentation of testing result is realized, it is straight convenient for healthcare givers and patient The current artery state of the understanding of sight.
Detailed description of the invention
Fig. 1 is a kind of system block diagram of the early screening system of peripheral arteriosclerosis of the embodiment of the present invention.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention Protection scope.
As shown in Figure 1, a kind of early screening system of peripheral arteriosclerosis of the embodiment of the present invention, comprising:
Human-machine operation module, for inputting patient basis and funduscopy result data;
Pulse wave signal acquisition module carries out patient body pulse wave signal everywhere based on infrared electro data pick-up Acquisition;
Blood flow signal acquisition module carries out adopting for lumen of vessels form and blood flow state data based on supersonic doppler detector Collection;
Data preprocessing module, by depth convolution model respectively to the funduscopy result data of acquisition, everywhere pulse Wave signal and lumen of vessels form and blood flow state data carry out feature extraction;
Human body artery model construction module according to the patient basis and extracts resulting spy based on Simulink Levy the building that data carry out human body artery model emulation model;
Virtual actuator is established with each element in human body artery model construction module and is closed for driving Parameters variation After system, parameter can be changed in specified range, be directed to different parameters so as to driving simulation analysis method Carry out calculating solution;And the position for changing transfering node, direction setting, it realizes human body artery model sport, decomposes, cuts It cuts, amplify and reduces;
Virtual parameter module, for the target that can directly acquire corresponding result or information being inserted into human body artery model Logic unit;
Simulation analysis module, the control command for being inputted according to human-computer interaction module drive corresponding simulation analysis algorithm To the virtual actuator, virtual actuator circulation executes the simulation analysis algorithm and result is fed back to simulation analysis module, The simulation analysis module automatically extracts target component and gives virtual parameter module, and the virtual parameter module is received and shown automatically Target component;
Forecast analysis module establishes short-term forecast unit using statistical regression and data-driven method, obtained by extracting Characteristic generate short-term artery and develop forecast information;
Inspection result display module, by obtaining lumen of vessels form and blood flow state corresponding under different pulse wave signals Data establish the PLSR mould of pulse wave signal and lumen of vessels form and blood flow state data on the basis of gained pulse wave signal Type obtains the pulse wave signal of each pixel on image, the pulse of each pixel is made by way of being converted into color-values The visualization of wave signal distributions situation.
Graphic plotting module, for according to the funduscopy result data, everywhere pulse wave signal and lumen of vessels shape State and blood flow state data draw various visualized graphs;
Comparative analysis module will draw visualized graphs and visualized graphs and last inspection knot under normal circumstances The corresponding visualized graphs of fruit compare and analyze and predict that prediction result is analyzed in output.
Control prece decision-premaking module analyzes result for the typical human body artery model emulation model emulation of store various types And its corresponding control prece model, for each simulation analysis result received to be carried out similar degree pair with the data stored Than, and by comparison result according to similarity carry out ascending or descending order sequence after, be sent to human-machine operation module and shown;
Three-dimensional display module, by moulding light modules, using phantom imaging film as image forming medium optical imagery module, Video display playing module, computer media module and control module composition, are erected on the desk of diagnosis and treatment doctor, are used for basis The resulting result of inspection result display module calls corresponding data to generate artery three-dimensional stereo model in materials database;
Central processing unit, for coordinating above-mentioned each module work.
In the present embodiment, the graphic plotting module is used for the control command inputted according to human-machine operation module, calls phase Data source and draw requirement of the mapping program answered based on selection, complete the automatic drafting of figure.The comparative analysis module For the control command for inputting according to human-machine operation module, corresponding visualization of the comparative analysis program based on selection is called Figure, completes the automatic comparative analysis of multiple figures, and exports analysis prediction result.
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned Particular implementation, those skilled in the art can make a variety of changes or modify within the scope of the claims, this not shadow Ring substantive content of the invention.In the absence of conflict, the feature in embodiments herein and embodiment can any phase Mutually combination.

Claims (7)

1. a kind of early screening system of peripheral arteriosclerosis, it is characterised in that: include:
Human-machine operation module, for inputting patient basis and funduscopy result data;
Pulse wave signal acquisition module, carrying out patient body based on infrared electro data pick-up, pulse wave signal is adopted everywhere Collection;
Blood flow signal acquisition module carries out the acquisition of lumen of vessels form and blood flow state data based on supersonic doppler detector;
Data preprocessing module, by depth convolution model respectively to the funduscopy result data of acquisition, everywhere pulse wave believe Number and lumen of vessels form and blood flow state data carry out feature extraction;
Human body artery model construction module according to the patient basis and extracts resulting characteristic based on Simulink According to the building for carrying out human body artery model emulation model;
Virtual actuator, for driving Parameters variation, after each element opening relationships in human body artery model construction module, Parameter can be changed in specified range, be counted so as to driving simulation analysis method for different parameters It calculates and solves;And the position for changing transfering node, direction setting, realize human body artery model sport, decomposition, cutting, amplification And diminution;
Virtual parameter module is patrolling for the target that can directly acquire corresponding result or information being inserted into human body artery model Collect unit;
Simulation analysis module, the control command for being inputted according to human-computer interaction module drive corresponding simulation analysis algorithm to institute Virtual actuator is stated, virtual actuator circulation executes the simulation analysis algorithm and result is fed back to simulation analysis module, described Simulation analysis module automatically extracts target component and gives virtual parameter module, and the virtual parameter module receives and automatic displaying target Parameter;
Forecast analysis module establishes short-term forecast unit using statistical regression and data-driven method, utilizes the resulting spy of extraction It levies data and generates short-term artery development forecast information.
2. a kind of early screening system of peripheral arteriosclerosis as described in claim 1, it is characterised in that: further include an inspection As a result display module, by obtaining lumen of vessels form and blood flow state data corresponding under different pulse wave signals, in gained The PLSR model of pulse wave signal and lumen of vessels form and blood flow state data is established on the basis of pulse wave signal, is obtained on image The pulse wave signal of each pixel makes the pulse wave signal distribution situation of each pixel by way of being converted into color-values Visualization.
3. a kind of early screening system of peripheral arteriosclerosis as described in claim 1, it is characterised in that: further include:
Graphic plotting module, for according to the funduscopy result data, everywhere pulse wave signal and lumen of vessels form and Blood flow state data draw various visualized graphs;
Comparative analysis module, visualized graphs and last inspection result pair by drafting visualized graphs and under normal circumstances The visualized graphs answered compare and analyze and predict that prediction result is analyzed in output.
4. a kind of early screening system of peripheral arteriosclerosis as described in claim 1, it is characterised in that: further include:
Control prece decision-premaking module, for store various types typical human body artery model emulation model emulation analysis result and its Corresponding control prece model, for each simulation analysis result received to be carried out similar degree comparison with the data stored, And by comparison result according to similarity carry out ascending or descending order sequence after, be sent to human-machine operation module and shown.
5. a kind of early screening system of peripheral arteriosclerosis as claimed in claim 3, it is characterised in that: the graphic plotting Module is used for the control command that inputs according to human-machine operation module, call data source of the corresponding mapping program based on selection and It draws and requires, complete the automatic drafting of figure.
6. a kind of early screening system of peripheral arteriosclerosis as claimed in claim 3, it is characterised in that: the comparative analysis Module for control command for being inputted according to human-machine operation module, call corresponding comparative analysis program based on selection can Depending on changing figure, the automatic comparative analysis of multiple figures is completed, and export analysis prediction result.
7. a kind of early screening system of peripheral arteriosclerosis as described in claim 1, it is characterised in that: further include a three-dimensional Display module plays mould as the optical imagery module of image forming medium, video display by moulding light modules, using phantom imaging film Block, computer media module and control module composition, are erected on the desk of diagnosis and treatment doctor, for according to inspection result exhibition Show that the resulting result of module calls corresponding data to generate artery three-dimensional stereo model in materials database.
CN201811298283.7A 2018-10-26 2018-10-26 A kind of early screening system of peripheral arteriosclerosis Withdrawn CN109192308A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020168696A1 (en) * 2019-02-22 2020-08-27 未艾医疗技术(深圳)有限公司 Vrds 4d medical image-based artery and vein ai processing method and product
WO2021249034A1 (en) * 2020-06-08 2021-12-16 华为技术有限公司 Method and device for generating arteriosclerosis detection interface, terminal, and system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020168696A1 (en) * 2019-02-22 2020-08-27 未艾医疗技术(深圳)有限公司 Vrds 4d medical image-based artery and vein ai processing method and product
WO2021249034A1 (en) * 2020-06-08 2021-12-16 华为技术有限公司 Method and device for generating arteriosclerosis detection interface, terminal, and system
CN113838567A (en) * 2020-06-08 2021-12-24 华为技术有限公司 Arteriosclerosis detection interface generation method, device, terminal and system
CN113838567B (en) * 2020-06-08 2023-04-07 华为技术有限公司 Arteriosclerosis detection interface generation method, device, terminal and system

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